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Volumn 11, Issue 2, 2012, Pages 172-182

Induction of apoptosis of tumor cells by some potentiated homeopathic drugs: Implications on mechanism of action

Author keywords

apoptosis; DNA microarray; homeopathy

Indexed keywords

CARCINOSINUM 200C; CASPASE 3; COMPLEMENTARY DNA; COMPLEMENTARY RNA; DNA; HOMEOPATHIC AGENT; HYDRASTIS 200C; PROTEIN BCL 2; PROTEIN P53; RNA; RUTA 200C; THUJA 1M; THUJA 200C; UNCLASSIFIED DRUG;

EID: 84862010364     PISSN: 15347354     EISSN: 1552695X     Source Type: Journal    
DOI: 10.1177/1534735411400310     Document Type: Article
Times cited : (38)

References (41)
  • 2
    • 3242786586 scopus 로고    scopus 로고
    • Homeopathy in cancer care: Part I. An introduction to "like curing like."
    • Rosser C. Homeopathy in cancer care: part I. An introduction to "like curing like." Clin J Oncol Nurs. 2004;8:24-26.
    • (2004) Clin J Oncol Nurs , vol.8 , pp. 24-26
    • Rosser, C.1
  • 4
    • 0028178862 scopus 로고
    • Pursuit and practice of complementary therapies by cancer patients receiving conventional treatment
    • Downer SM, Cody MM, McCluskey P, et al. Pursuit and practice of complementary therapies by cancer patients receiving conventional treatment. BMJ. 1994;309:86-89.
    • (1994) BMJ , vol.309 , pp. 86-89
    • Downer, S.M.1    Cody, M.M.2    McCluskey, P.3
  • 5
    • 3042606421 scopus 로고    scopus 로고
    • Ruta 6 selectively induces cell death in brain cancer cells but proliferation in normal peripheral blood lymphocytes: A novel treatment for human brain cancer
    • Pathak S, Multani AS, Banerji P, Banerji P. Ruta 6 selectively induces cell death in brain cancer cells but proliferation in normal peripheral blood lymphocytes: a novel treatment for human brain cancer. Int J Oncol. 2003;23:975-982.
    • (2003) Int J Oncol , vol.23 , pp. 975-982
    • Pathak, S.1    Multani, A.S.2    Banerji, P.3    Banerji, P.4
  • 6
    • 0035055447 scopus 로고    scopus 로고
    • Intracranial cysticercosis: An effective treatment with alternative medicines
    • Banerji P, Banerji P. Intracranial cysticercosis: an effective treatment with alternative medicines. In Vivo. 2001;15:181-184. (Pubitemid 32328193)
    • (2001) In Vivo , vol.15 , Issue.2 , pp. 181-184
    • Banerji, P.1    Banerji, P.2
  • 9
    • 3042805454 scopus 로고    scopus 로고
    • Evaluation of protective potentials of a potentized homeopathic drug, Chelidonium majus, during azo dye induced hepatocarcinogenesis in mice
    • Biswas SJ, Khuda-Bukhsh AR. Evaluation of protective potentials of a potentized homeopathic drug Chelidonium majus during azo dye induced hepatocarcinogenesis in mice. Indian J Exp Biol. 2004;42:698-714. (Pubitemid 38889462)
    • (2004) Indian Journal of Experimental Biology , vol.42 , Issue.7 , pp. 698-714
    • Biswas, S.J.1    Khuda-Bukhsh, A.R.2
  • 10
    • 28444450816 scopus 로고    scopus 로고
    • Efficacy of the potentized homeopathic drug, Carcinosin 200, fed alone and in combination with another drug, Chelidonium 200, in amelioration of p-dimethylaminoazobenzene-induced hepatocarcinogenesis in mice
    • DOI 10.1089/acm.2005.11.839
    • Biswas SJ, Pathak S, Khuda-Bukhsh AR. Efficacy of a potentized homeopathic drug, Carcinosin-200, fed alone and in combination with another drug, Chelidonium 200, in amelioration of p-DAB induced hepatocarcinogenesis in mice. J Altern Complement Med. 2005;11:839-854. (Pubitemid 41739356)
    • (2005) Journal of Alternative and Complementary Medicine , vol.11 , Issue.5 , pp. 839-854
    • Biswas, S.J.1    Pathak, S.2    Bhattacharjee, N.3    Das, J.K.4    Khuda-Bukhsh, A.R.5
  • 11
    • 79953274036 scopus 로고    scopus 로고
    • Evidences of protective potentials of microdoses of ultra-high diluted arsenic trioxide in mice receiving repeated injections of arsenic trioxide
    • published online ahead of print February 25, doi:10.1093/ecam/nen090
    • Banerjee P, Bhattacharyya SS, Pathak S, Boujedaini N, Belon P, Khuda-Bukhsh AR. Evidences of protective potentials of microdoses of ultra-high diluted arsenic trioxide in mice receiving repeated injections of arsenic trioxide [published online ahead of print February 25, 2009]. Evid Based Complement Alternat Med. doi:10.1093/ecam/nen090.
    • (2009) Evid Based Complement Alternat Med
    • Banerjee, P.1    Bhattacharyya, S.S.2    Pathak, S.3    Boujedaini, N.4    Belon, P.5    Khuda-Bukhsh, A.R.6
  • 16
    • 3242692268 scopus 로고    scopus 로고
    • Inhibition of IL-1beta and TNF-alpha secretion from resting and activated human immunocytes by the homeopathic medication Traumeel S
    • DOI 10.1080/10446670410001722203
    • Porozov S, Cahalon L, Weisesr M, Branski D, Lider O, Oberbaum M. Inhibition of IL-1 beta and TNF-alpha secretion from resting and activated human immunocytes by homeopathic medication Traumeel S. Clin Dev Immunol. 2004;11: 143-149. (Pubitemid 38955071)
    • (2004) Clinical and Developmental Immunology , vol.11 , Issue.2 , pp. 143-149
    • Porozov, S.1    Cahalon, L.2    Weiser, M.3    Branski, D.4    Lider, O.5    Oberbaum, M.6
  • 17
    • 34249013687 scopus 로고    scopus 로고
    • Investigation of cytokine expression in human leukocyte cultures with two immune-modulatory homeopathic preparations
    • DOI 10.1089/acm.2007.6292
    • Ramachandran C, Raveendran Nair PK, Clèment RT, Melnick SJ. Investigation of cytokine expression in human leukocyte cultures with two immune-modulatory homeopathic preparations. J Altern Complement Med. 2007;13:403-407. (Pubitemid 46802344)
    • (2007) Journal of Alternative and Complementary Medicine , vol.13 , Issue.4 , pp. 403-407
    • Ramachandran, C.1    Nair, P.K.R.2    Clement, R.T.3    Melnick, S.J.4
  • 18
    • 33751574998 scopus 로고
    • Committee on Pharmacopoeia of the American Institute of Homeopathy. 6th ed. Boston, MA: Otis Clapp
    • Committee on Pharmacopoeia of the American Institute of Homeopathy. The Homeopathic Pharmacopoeia of the United States. 6th ed. Boston, MA: Otis Clapp; 1954.
    • (1954) The Homeopathic Pharmacopoeia of the United States
  • 20
    • 39049176427 scopus 로고    scopus 로고
    • Antitumor activity of Ruta graveolens extract
    • Preethi KC, Kuttan R. Antitumor activity of Ruta graveolens extract. Asian Pac J Cancer Prev. 2006;7:439-443.
    • (2006) Asian Pac J Cancer Prev , vol.7 , pp. 439-443
    • Preethi, K.C.1    Kuttan, R.2
  • 21
    • 35648983019 scopus 로고    scopus 로고
    • DNA binding suppresses human AIF-M2 activity and provides a connection between redox chemistry, reactive oxygen species, and apoptosis
    • DOI 10.1074/jbc.M703713200
    • Gong SM, Hay S, Marshall KR, Munro AW, Scrutton NS. DNA binding suppresses human AIF-M2 activity and provides a connection between redox chemistry, reactive oxygen species, and apoptosis. J Biol Chem. 2007;282:30331-30340. (Pubitemid 350035262)
    • (2007) Journal of Biological Chemistry , vol.282 , Issue.41 , pp. 30331-30340
    • Gong, M.1    Hay, S.2    Marshall, K.R.3    Munro, A.W.4    Scrutton, N.S.5
  • 22
    • 0036090902 scopus 로고    scopus 로고
    • Polyphenols in red wine inhibit the proliferation and induce apoptosis of LNCaP cells
    • DOI 10.1046/j.1464-410X.2002.02790.x
    • Romero I, Páez A, Ferruelo A, Luján M, Berenguer A. Polyphenols in red wine inhibit the proliferation and induce apoptosis of LNCaP cells. BJU Int. 2002;89:950-954. (Pubitemid 34535434)
    • (2002) BJU International , vol.89 , Issue.9 , pp. 950-954
    • Romero, I.1    Paez, A.2    Ferruelo, A.3    Lujan, M.4    Berenguer, A.5
  • 23
    • 27844549408 scopus 로고    scopus 로고
    • Effect of phenols on natural killer (NK) cell-mediated death in the K562 human leukemic cell line
    • DOI 10.1016/j.cellbi.2005.07.006, PII S1065699505001642
    • Dedoussis GV, Kaliora AC, Andrikopoulos NK. Effect of phenols on natural killer (NK) cell-mediated death in the K562 human leukemic cell line. Cell Biol Int. 2005;29:884-889. (Pubitemid 41654791)
    • (2005) Cell Biology International , vol.29 , Issue.11 , pp. 884-889
    • Dedoussis, G.V.Z.1    Kaliora, A.C.2    Andrikopoulos, N.K.3
  • 24
    • 75449107545 scopus 로고    scopus 로고
    • Cytotoxic effects of ultra-diluted remedies on breast cancer cells
    • Frenkel M, Mishra BM, Sen S, et al. Cytotoxic effects of ultra-diluted remedies on breast cancer cells. Int J Oncol. 2010;36:395-402.
    • (2010) Int J Oncol , vol.36 , pp. 395-402
    • Frenkel, M.1    Mishra, B.M.2    Sen, S.3
  • 25
    • 34247200969 scopus 로고    scopus 로고
    • RhoA/Rho kinase up-regulate Bax to activate a mitochondrial death pathway and induce cardiomyocyte apoptosis
    • DOI 10.1074/jbc.M604298200
    • Del Re DP, Miyamoto S, Brown JH. RhoA/Rho kinase upregulate Bax to activate a mitochondrial death pathway and induce cardiomyocyte apoptosis. J Biol Chem. 2007;282:8069-8078. (Pubitemid 47093605)
    • (2007) Journal of Biological Chemistry , vol.282 , Issue.11 , pp. 8069-8078
    • Del, R.D.P.1    Miyamoto, S.2    Brown, J.H.3
  • 27
    • 0033936787 scopus 로고    scopus 로고
    • Bax, Bid and the permeabilization of the mitochondrial outer membrane in apoptosis
    • DOI 10.1016/S0955-0674(00)00110-1
    • Crompton M. Bax, Bid and the permeabilization of the mitochondrial outer membrane in apoptosis. Curr Opin Cell Biol. 2000;12:414-419. (Pubitemid 30453590)
    • (2000) Current Opinion in Cell Biology , vol.12 , Issue.4 , pp. 414-419
    • Crompton, M.1
  • 28
    • 0033521741 scopus 로고    scopus 로고
    • Molecular characterization of mitochondrial apoptosis-inducing factor
    • Susin SA, Lorenzo HK, Zamzami N, et al. Molecular characterization of mitochondrial apoptosis-inducing factor. Nature. 1999;397:441-446.
    • (1999) Nature , vol.397 , pp. 441-446
    • Susin, S.A.1    Lorenzo, H.K.2    Zamzami, N.3
  • 29
    • 0034617449 scopus 로고    scopus 로고
    • Apoptosis-inducing factor (AIF): A ubiquitous mitochondrial oxidoreductase involved in apoptosis
    • DOI 10.1016/S0014-5793(00)01731-2, PII S0014579300017312
    • Daugas E, Nochy D, Ravagnan L, et al. Apoptosis-inducing factor (AIF): a ubiquitous mitochondrial oxidoreductase involved in apoptosis. FEBS Lett. 2000;476:118-123. (Pubitemid 30410801)
    • (2000) FEBS Letters , vol.476 , Issue.3 , pp. 118-123
    • Daugas, E.1    Nochy, D.2    Ravagnan, L.3    Loeffler, M.4    Susin, S.A.5    Zamzami, N.6    Kroemer, G.7
  • 30
    • 0037174180 scopus 로고    scopus 로고
    • Identification of a caspase 3-independent role of pro-apoptotic factor Bak in TNF-alphainduced apoptosis
    • Eigo S, Hiroaki K, Kazunari T. Identification of a caspase 3-independent role of pro-apoptotic factor Bak in TNF-alphainduced apoptosis. FEBS Lett. 2002;528:63-69.
    • (2002) FEBS Lett , vol.528 , pp. 63-69
    • Eigo, S.1    Hiroaki, K.2    Kazunari, T.3
  • 33
    • 18244379872 scopus 로고    scopus 로고
    • Homeodomaininteracting protein kinase-2 phosphorylates p53 at Ser 46 and mediates apoptosis
    • D'Orazi G, Cecchinelli B, Bruno T, et al. Homeodomaininteracting protein kinase-2 phosphorylates p53 at Ser 46 and mediates apoptosis. Nat Cell Biol. 2002;4:11-19.
    • (2002) Nat Cell Biol , vol.4 , pp. 11-19
    • D'Orazi, G.1    Cecchinelli, B.2    Bruno, T.3
  • 34
    • 33847067437 scopus 로고    scopus 로고
    • Upregulation of two BH3-only proteins, Bmf and Bim, during TGF beta-induced apoptosis
    • Ramjaun AR, Tomlinson S, Eddaoudi A, Downward J. Upregulation of two BH3-only proteins, Bmf and Bim, during TGF beta-induced apoptosis. Oncogene. 2007;26:970-981.
    • (2007) Oncogene , vol.26 , pp. 970-981
    • Ramjaun, A.R.1    Tomlinson, S.2    Eddaoudi, A.3    Downward, J.4
  • 35
    • 33748749185 scopus 로고    scopus 로고
    • The death domain kinase RIP has an important role in DNA damage-induced, p53-independent cell death
    • DOI 10.1074/jbc.M605577200
    • Hur GM, Kim YS, Won M, Choksi S, Liu ZG. The death domain kinase RIP has an important role in DNA damageinduced, p53-independent cell death. J Biol Chem. 2006;281: 25011-25017. (Pubitemid 44401889)
    • (2006) Journal of Biological Chemistry , vol.281 , Issue.35 , pp. 25011-25017
    • Gang, M.H.1    Kim, Y.-S.2    Won, M.3    Choksi, S.4    Liu, Z.-G.5
  • 40
    • 0142243234 scopus 로고    scopus 로고
    • Towards understanding molecular mechanisms of action of homeopathic drugs: An overview
    • DOI 10.1023/A:1026048907739
    • Khuda-Bukhsh AR. Towards understanding molecular mechanisms of action of homeopathic drugs: an overview. Mol Cell Biochem. 2003;253:339-345. (Pubitemid 37321741)
    • (2003) Molecular and Cellular Biochemistry , vol.253 , Issue.1-2 , pp. 339-345
    • Khuda-Bukhsh, A.R.1
  • 41
    • 0030970288 scopus 로고    scopus 로고
    • Potentized homeopathic drugs act through regulation of gene-expression: A hypothesis to explain their mechanism and pathways of action in vivo
    • Khuda-Bukhsh AR. Potentized homeopathic drugs act through regulation of gene-expression: a hypothesis to explain their mechanism and pathways of action in vivo. Complement Ther Med. 1997;5:43-46.
    • (1997) Complement Ther Med , vol.5 , pp. 43-46
    • Khuda-Bukhsh, A.R.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.