Antianxiety activity of Gelsemium sempervirens

Pharmaceutical Biology

Volumn 48, Issue 10, 2010, Pages 1091-1096

  Dutt, Vandana ^a   Dhar, V J ^b   Sharma, Anupam ^c  

^a Guru Gobind Singh College of Pharmacy   (India)

^b Swift School of Pharmacy   (India)

^c PANJAB UNIVERSITY   (India)

Author keywords

Anxiolytic; Bioactivity directed fractionation; Column chromatography; Elevated plus maze test; Gelsemium sempervirens; Yellow jasmine

Indexed keywords

ALKALOID; ANXIOLYTIC AGENT; CHLOROFORM; DIAZEPAM; GELSEMIUM SEMPERVIRENS EXTRACT; IRIDOID; METHANOL; PETROLEUM ETHER; PLANT EXTRACT; STEROID; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; BEHAVIOR DISORDER; COLUMN CHROMATOGRAPHY; CONTROLLED STUDY; DOSE RESPONSE; DRUG DETERMINATION; DRUG EFFECT; DRUG ISOLATION; DRUG MECHANISM; DRUG SCREENING; FEMALE; FRACTIONATION; GELSEMIUM; GELSEMIUM SEMPERVIRENS; MALE; MAZE TEST; MOTOR COORDINATION; MOUSE; NONHUMAN; PHYTOCHEMISTRY; PLANT ROOT; RHIZOME; TOXICITY TESTING; TRANQUILIZING ACTIVITY;

ANIMALS; ANTI-ANXIETY AGENTS; ANXIETY; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; GELSEMIUM; MALE; MAZE LEARNING; MICE; PHYTOTHERAPY; PLANT EXTRACTS; PLANT ROOTS;

GELSEMIUM SEMPERVIRENS; JASMINUM ODORATISSIMUM; LOGANIACEAE; MUS;

EID: 77957039630     PISSN: 13880209     EISSN: 17445116     Source Type: Journal    
DOI: 10.3109/13880200903490521     Document Type: Article

References (25)

1. Bhattamisra SK, Khanna VK, Aggarwal AK, Singh PN, Singh SK (2008): Antidepressant activity of standardized extract of Marsilea minuta Linn. J Ethnopharmacol. 117: 51-57.
2. Calarasu C (1989): Pharmaceutical containing diphenhydramine and Echinaceae and Eupatorium and Gelsemium and Lachesris for the treatment of psoriasis and neurodermititis. German Patent No. 3641220, 4, 1988. Chem Abstr. 110: 141559.
3. Dhawan K, Kumar S, Sharma A (2001): Antianxiety studies on extract of Passiflora incarnata Linneaus. J Ethnopharmacol. 78: 165-170.
4. Dunham MW, Miya TS (1957): A note on a simple apparatus for detecting neurological deficits in rats and mice. J Am Pharm Assoc Sci. 46: 208-209.
5. Emamghoreishi M, Khasaki M, Aazam MF (2005): Coriandrum sativum: Evaluation of its anxiolytic effect in the elevated plusmaze. J Ethnopharmacol. 96: 365-370.
6. Farnsworth NR (1966): Biological and phytochemical screening of plants. J Pharm Sci. 55: 225-286.
7. Felter HW, Lloyd JU (1983): Gelsemium (U.S.P.) - Gelsemium. In: Kings American Dispensatory [online]. Avaliable at: http:// www.ibilio.org/herbmed/ kings/gelsemium.htm. Accessed 23 August 2006.
8. Hoggs S (1996): A review of the validity and variability of the elevated plus maze as an animal model of anxiety. Pharmacol Biochem Behav. 54: 21-30.
9. Jensen SR, Kirk O, Nielsen BJ, Norrestam R (1987): 9-Hydroxy substituted iridiods from Gelsemium sempervirens. Phytochemistry. 26: 1725-1731.
10. Kogure N, Nishiya C, Kitajima M, Takayama H (2005): Six new indole alkaloids from G. sempervirens Ait. Tetrahedron Lett. 46: 5857-5861.
11. Kulkarni SK, Reddy DS (1996): Animal behavioural models for testing antianxiety agents. Method Findings Exp Clin Pharmacol.18: 219-230.
12. Kumar S, Sharma A (2006): Apigenin - the anxiolytic constituent of Turnera aphrodisiaca Ward. Pharm Biol. 44: 84-90.
13. Lister RG (1987): The use of a plus maze to measure anxiety in the mouse. Psychopharmacology. 92: 180-185.
14. Mitte K, Noack P, Steil R, Hautzinger M (2005): A meta-analytic review of the efficacy of drug treatment in generalized anxiety disorder. J Clin Psychopharmacol. 25: 141-150.
15. Nebera SA, Nebera OA, Pakhomova NN (2003): Homoeopathic preparation for treating myopia. RU Patent No. 2203674. Chem Abst. 139: 219298.
16. OECD (1996). Test No. 423: Acute oral toxicity - acute toxic class method. In: OECD Guidelines for the Testing of Chemicals. Paris, OECD.
17. Pellow S, Chopin P, File SE, Briley M (1985): Validation of open:closed arm entries in an elevated plus-maze as a measure of anxiety in the rat. J Neurosci Methods. 14: 149-176.
18. Peng W, Hsieh M, Lee Y, Lin Y, Liao J (2000): Anxiolytic effect of seed of Ziziphus jujube in mouse models of anxiety. J Ethnopharmacol. 72: 435-441.
19. Rabbani M, Sajjadi SE, Jafarian A, Vaseghi G (2005): Anxiolytic effect of Salvia reuterana Bioss on the elevated plus maze model of anxiety in mice. J Ethnopharmacol. 101: 100-103.
20. Raupp IM, Sereniki A, Virtuoso S, Ghislandi C, Cavalcanti e Silva EL, Trebien HA, Miguel OG, Andreatini R (2008): Anxiolytic-like effects of chronic treatments with Erythrina velutina extract in the elevated plus-maze test. J Ethnopharmacol. 118: 295-299.
21. Reynolds EH (2003): Brain and mind: A challenge for WHO. Lancet. 361: 1924-1925.
22. Rodgers RJ (1997): Animal model of anxiety: Where next? Behav Pharmacol 8: 477-496.
23. Voorhees J, Nachman L (2002): Herbal composition for treating symptoms of influenza. United States Patent No. 64550703. Chem Abstr. 137: 159364.
24. Wenkert E, Chang CJ, Corchan DW, Polliccari R (1972): 13C nuclear magnetic resonance spectroscopy of naturally occurring substances, VIII. Structure of gelsevirine. Experientia. 28: 377-379.
25. WHO (2001): The world health report 2001 - Mental health: New understanding, new hope. Geneva, WHO.