Bacillus anthracis cell wall produces injurious inflammation but paradoxically decreases the lethality of anthrax lethal toxin in a rat model

Intensive Care Medicine

Volumn 36, Issue 1, 2010, Pages 148-156

  Cui, Xizhong ^a   Su, Junwu ^a   Li, Yan ^a   Shiloach, Joseph ^b   Solomon, Steven ^a   Kaufman, Jeanne B ^b   Mani, Haresh ^c   Fitz, Yvonne ^a   Weng, Jia ^a   Altaweel, Laith ^a   Besch, Virginia ^a   Eichacker, Peter Q ^a  

^a NATIONAL INSTITUTES OF HEALTH   (United States)

^b NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

^c NATIONAL CANCER INSTITUTE   (United States)

Author keywords

Bacillus anthracis; Cardiopulmonary dysfunction; Cell wall; Cytokine release; Inflammation

Indexed keywords

ANTHRAX TOXIN; CYTOKINE; DILUENT; LIPOPOLYSACCHARIDE; NITRIC OXIDE;

ANIMAL CELL; ANIMAL MODEL; ANTHRAX; ARTICLE; BACILLUS ANTHRACIS; BACTERIAL CELL WALL; COMPARATIVE STUDY; CONTROLLED STUDY; HYPOTENSION; HYPOXEMIA; INFLAMMATION; INFUSION; LETHALITY; NEUTROPHIL; NONHUMAN; PATHOGENICITY; RAT; SPRAGUE DAWLEY RAT; STAPHYLOCOCCUS AUREUS; THROMBOCYTE;

ANIMALS; BACILLUS ANTHRACIS; BACTERIAL INFECTIONS; BACTERIAL TOXINS; BLOOD PLATELETS; CELL WALL; DISEASE MODELS, ANIMAL; KAPLAN-MEIERS ESTIMATE; LYMPHOCYTES; NEUTROPHILS; RANDOM ALLOCATION; RATS; RATS, SPRAGUE-DAWLEY; STAPHYLOCOCCUS AUREUS; TIME FACTORS;

EID: 76549089581     PISSN: 03424642     EISSN: 14321238     Source Type: Journal    
DOI: 10.1007/s00134-009-1643-9     Document Type: Article

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