Like cures like: A neuroimmunological model based on electromagnetic resonance

Electromagnetic Biology and Medicine

Volumn 32, Issue 4, 2013, Pages 508-526

  Shahabi, Shahram ^a   Kasariyans, Aditya ^b   Noorbakhsh, Farshid ^c  

^a URMIA UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^b Homeopath   (Iran)

^c TEHRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

Cholinergic anti inflammatory reflex; Extremely low frequency electromagnetic waves; Homeopathy; Nanostructures; Resonance

Indexed keywords

AMPLITUDE CHARACTERISTICS; ANTI-INFLAMMATORIES; ELECTROMAGNETIC RESONANCE; EXTREMELY LOW FREQUENCIES; HOMEOPATHIC MEDICINES; HOMEOPATHY; PHYSIOLOGICAL CONDITION; REGULATORY MECHANISM;

ELECTROMAGNETISM; NANOSTRUCTURES; NEURONS; PHYSIOLOGICAL MODELS; PHYSIOLOGY; RESONANCE;

ELECTROMAGNETIC WAVES;

ARTICLE; BIOLOGICAL MODEL; ELECTROMAGNETIC FIELD; HOMEOPATHY; HUMAN; IMMUNOLOGY; INFLAMMATION; METHODOLOGY; NEUROSCIENCE;

ELECTROMAGNETIC PHENOMENA; HOMEOPATHY; HUMANS; INFLAMMATION; MODELS, IMMUNOLOGICAL; NEUROSCIENCES;

EID: 84887872593     PISSN: 15368378     EISSN: 15368386     Source Type: Journal    
DOI: 10.3109/15368378.2012.743911     Document Type: Article

References (107)

1. Assa J, Litime MH, Attias E, Benveniste J (1993). Molecular signaling at high dilution or by means of electronic circuitry. J. Immunol. 150:A146.
2. Anderson LE (1993). Biological effects of extremely low-frequency electromagnetic fields: in vivo studies. Am. Ind. Hyg. Assoc. J. 54:186-196.
3. Andrew D, Greenspan JD (1999). Mechanical and heat sensitization of cutaneous nociceptors after peripheral inflammation in the rat. J. Neurophysiol. 82:2649-2656.
4. Anelli M, Scheepers L, Sermeus G, Van Wassenhoven M (2002). Homeopathy and health related quality of life: A survey in six European countries. Homeopathy 91:18-21.
5. Bellamy JL, Cady RK, Durham PL (2006). Salivary levels of CGRP and VIP in rhinosinusitis and migraine patients. Headache 46:24-33.
6. Bellavite P, Conforti A, Piasere V, Ortolani R (2005). Immunology and homeopathy. 1. Historical background. Evid. Based Complement. Alternat. Med. 2:441-452.
7. Bellavite P, Ortolani R, Pontarollo F, Pitari G, Conforti A (2007). Immunology and homeopathy. 5. The rationale of the 'Simile'. Evid. Based Complement. Alternat. Med. 4:149-163.
8. Benveniste J, Assa J, Litime MH, Tsangaris G, Thomas Y (1994). Transfer of the molecular signal by electronic amplification. FASEB J. 8:A398.
9. Benveniste J, Ducot B, Spira A (1994). Memory of water revisited. Nature 370:322.
10. Bercik P, Verdu EF, Foster JA, Macri J, Potter M, Huang X, Malinowski P, et al. (2010). Chronic gastrointestinal inflammation induces anxiety-like behavior and alters central nervous system biochemistry in mice. Gastroenterology 139:2102-2112e1.
11. Bonamin LV, editor (2008). Signals and images: contributions and contradictions of high dilution research. Dordrecht: Springer.
12. Borovikova LV, Ivanova S, Zhang M, Yang H, Botchkina GI, Watkins LR, Wang H, et al. (2000). Vagus nerve stimulation attenuates the systemic inflammatory response to endotoxin. Nature 405:458-462.
13. Carrubba S, Frilot II, C, Chesson Jr, AL, Marino AA (2007). Evidence of a nonlinear human magnetic sense. Neuroscience 144:356-367.
14. Cifra M, Fields JZ, Farhadi A (2011). Electromagnetic cellular interactions. Prog. Biophys. Mol. Biol. 105: 223-246.
15. Cifra M, Pokorny J, Kucera O, Havelka D (2011). Role of Organized water in coherence of cellular electromagnetics. The Sixth Annual Water Conference: conference on the physics, chemistry and biology of water. Mount Snow Resort, Vermont, USA.
16. Coderre TJ, Katz J (1997). Peripheral and central hyperexcitability: differential signs and symptoms in persistent pain. Behav. Brain Sci. 20:404-419 discussion 435-513.
17. Collins SM, Bercik P (2009). The relationship between intestinal microbiota and the central nervous system in normal gastrointestinal function and disease. Gastroenterology 136:2003-2014.
18. Czura CJ, Tracey KJ (2005). Autonomic neural regulation of immunity. J. Intern. Med. 257:156-166.
19. Czura CJ, Rosas-Ballina M, Tracey KJ. Cholinergic regulation of inflammation. In: Ader R, editor. Psychoneuroimmunology. Amsterdam: Elsevier; (2007). pp 85-96.
20. Davenas E, Beauvais F, Amara J, Oberbaum M, Robinzon B, Miadonna A, Tedeschi A, et al. (1988). Human basophil degranulation triggered by very dilute antiserum against IgE. Nature 333: 816-818.
21. DeFerrariGM,Crijns HJ, Borggrefe M, SinovicG, Smid J,Zabel M,GavazziA, et al. (2011).Chronic vagus nerve stimulation: A new and promising therapeutic approach for chronic heart failure. Eur. Heart J. 32:847-855.
22. De Ferrari GM, Schwartz PJ (2011). Vagus nerve stimulation: from pre-clinical to clinical application: challenges and future directions. Heart Fail. Rev. 16:195-203.
23. De Herdt V, Puimege L, De Waele J, Raedt R, Wyckhuys T, El Tahry R, Libert C, et al. (2009). Increased rat serum corticosterone suggests immunomodulation by stimulation of the vagal nerve. J. Neuroimmunol. 212:102-105.
24. Demangeat J-L (2010). NMR relaxation evidence for solute-induced nanosized superstructures in ultramolecular aqueous dilutions of silica-lactose. J. Mol. Liquids 155:71-79.
25. de Tommaso M, Fiore P, Camporeale A, Guido M, Libro G, Losito L, Megna M, et al. (2003). High and low frequency transcutaneous electrical nerve stimulation inhibits nociceptive responses induced by CO2 laser stimulation in humans. Neurosci. Lett. 342:17-20.
26. Driban JB, Swanik CB, Huxel KC, Balsubramanian E (2007). Transient electric changes immediately after surgical trauma. J. Athl. Train. 42:524-529.
27. Endler PC, Pongratz W, Smith CW, Schulte J (1995). Non-molecular information transfer from thyroxine to frogs with regard to homeopathic toxicology. Vet. Hum. Toxicol. 37:259-260.
28. Fernandez-Cabezudo MJ, Lorke DE, Azimullah S, Mechkarska M, Hasan MY, Petroianu GA, al-Ramadi BK (2010). Cholinergic stimulation of the immune system protects against lethal infection by Salmonella enterica serovar Typhimurium. Immunology 130:388-398.
29. Frahm J, Lantow M, Lupke M, Weiss DG, Simkó M (2006). Alteration in cellular functions in mouse macrophages after exposure to 50 Hz magnetic fields. J. Cell Biochem. 99:168-177.
30. Giudice ED, Preparata G, Vitielo G (1988). Water as a free electric dipole laser. Phys. Rev. Lett. 61: 1085-1088.
31. Gopalkrishnan P, Sluka KA (2000). Effect of varying frequency, intensity, and pulse duration of transcutaneous electrical nerve stimulation on primary hyperalgesia in inflamed rats. Arch. Phys. Med. Rehabil. 81:984-990.
32. Grabia S, Ernst E (2003). Homeopathic aggravations: A systematic review of randomised, placebocontrolled clinical trials. Homeopathy 92:92-98.
33. Greaves MW (2007). Recent advances in pathophysiology and current management of itch. Ann. Acad. Med. Singapore 36:788-792.
34. Gross M, Goyal M (2007). Central therapeutic effects of peripheral vagus nerve stimulation. Am. J. Electroneurodiagnostic Technol. 47:47-52.
35. Guyton A, Hall J (2006). Textbook of medical physiology. Philadelphia, PA: Elsevier.
36. Hahnemann S (2004). Organon of medicine. New Delhi: B. Jain Publishers.
37. Hecht L (2011). New evidence for a non-particle view of life. E.I.R. 38:72-77.
38. Huston JM, Tracey KJ (2011). The pulse of inflammation: heart rate variability, the cholinergic antiinflammatory pathway and implications for therapy. J. Intern. Med. 269:45-53.
39. Hanggi P (2002). Stochastic resonance in biology. Eur. J. Chem. Phys. Phys. Chem. 3:285-290.
40. Jaradeh SS, Smith TL, Torrico L, Prieto TE, Loehrl TA, Darling RJ, Toohill RJ (2000). Autonomic nervous system evaluation of patients with vasomotor rhinitis. Laryngoscope 110:1828-1831.
41. Jarrett ME, Burr RL, Cain KC, Rothermel JD, Landis CA, Heitkemper MM (2008). Autonomic nervous system function during sleep among women with irritable bowel syndrome. Dig. Dis. Sci. 53:694-703.
42. Jenrow K, Liboff AR. Electromagnetic techniques in neural therapy. In: Rosch PJ, Markov MS, editors. Bioelectromagnetic medicine. New York: Marcel Dekker; (2004). pp 77-92.
43. Jonas WB, Ives JA, Rollwagen F, Denman DW, Hintz K, Hammer M, Crawford C (2006). Can specific biological signals be digitized FASEB J. 20:23-28.
44. Kaune WT, Stevens RG, Callahan NJ, Severson RK, Thomas DB (1987). Residential magnetic and electric fields. Bioelectromagnetics 8:315-335.
45. Khanaj VR (2006). Reperire: repertory simplified. New Delhi: Indian Books & Periodicals Publishers.
46. Kirchner A, Birklein F, Stefan H, Handwerker HO (2000). Left vagus nerve stimulation suppresses experimentally induced pain. Neurology 55:1167-1171.
47. Kirchner A, Stefan H, Bastian K, Birklein F (2006). Vagus nerve stimulation suppresses pain but has limited effects on neurogenic inflammation in humans. Eur. J. Pain 10:449-455.
48. Klein HU, Ferrari GM (2010). Vagus nerve stimulation: A new approach to reduce heart failure. Cardiol. J. 17:638-644.
49. Kox M, Hoedemaekers AW, Pickkers P, van der Hoeven JG, Pompe JC (2007). A possible role for the cholinergic anti-inflammatory pathway in increased mortality observed in critically ill patients receiving nicotine replacement therapy. Crit. Care Med. 35:2468-2469; author reply 2469.
50. Lacy-Hulbert A, Metcalfe JC, Hesketh R (1998). Biological responses to electromagnetic fields. FASEB J. 12: 395-420.
51. Lehner MD, Ittner J, Bundschuh DS, van Rooijen N, Wendel A, Hartung T (2001). Improved innate immunity of endotoxin-tolerant mice increases resistance to Salmonella enterica serovar Typhimurium infection despite attenuated cytokine response. Infect. Immun. 69:463-471.
52. Levine JD, Fields HL, Basbaum AI (1993). Peptides and the primary afferent nociceptor. J. Neurosci. 13: 2273-2286.
53. Levine JD, Reichling DB. Peripheral mechanisms of inflammatory pain. In: Wall PD, Melzack R, editors. Textbook of pain. Edinburgh: Churchill Livingston; (1999). pp 59-84.
54. Liboff AR. Signal shapes in electromagnetic therapies. In: Rosch PJ, Markov MS, editors. Bioelectromagnetic medicine. New York: Marcel Dekker; (2004). pp 77-92.
55. McKenna D, Beverstein G, Reichelderfer M, Gaumnitz E, Gould J (2008). Gastric electrical stimulation is an effective and safe treatment for medically refractory gastroparesis. Surgery 144:566-572 ; discussion 572-564.
56. Medzhitov R (2008). Origin and physiological roles of inflammation. Nature 454:428-435.
57. Mesirca P (2007). Electrical activity in neurons exposed to low level electromagnetic fields. Theory and experiments. Bologna: Università degli Studi di Bologna.
58. Meyer RA, Campbell JN (1981). Myelinated nociceptive afferents account for the hyperalgesia that follows a burn to the hand. Science 213:1527-1529.
59. Michaelis M, Vogel C, Blenk KH, Arnarson A, Janig W (1998). Inflammatory mediators sensitize acutely axotomized nerve fibers to mechanical stimulation in the rat. J. Neurosci. 18:7581-7587.
60. Millan MJ (1999). The induction of pain: An integrative review. Prog. Neurobiol. 57:1-164.
61. Millan MJ (2002). Descending control of pain. Prog. Neurobiol. 66:355-474.
62. Miller AH, Maletic V, Raison CL (2009). Inflammation and its discontents: The role of cytokines in the pathophysiology of major depression. Biol. Psychiatry 65:732-741.
63. Mishra N, Muraleedharan KC, Paranjpe AS, Munta DK, Singh H, Nayak C (2011). An exploratory study on scientific investigations in homeopathy using medical analyzer. J. Altern. Complement. Med. 17: 705-710.
64. Montagnier L, Aissa J, Ferris S, Montagnier J-L, Lavallée C (2009). Electromagnetic signals are produced by aqueous nanostructures derived from bacterial DNA sequences. Interdiscip. Sci. 1:81-90.
65. Montagnier L, Aissa J, Lavallee C, Mbamy M, Varon J, Chenal H (2009). Electromagnetic detection of HIV DNA in the blood of AIDS patients treated by antiretroviral therapy. Interdiscip. Sci. 1:245-253.
66. Nakamizo S, Egawa G, Miyachi Y, Kabashima K (2012). Cholinergic urticaria: pathogenesis-based categorization and its treatment options. J. Eur. Acad. Dermatol. Venereol 26:114-116.
67. Oke SL, Tracey KJ (2008). From CNI-1493 to the immunological homunculus: physiology of the inflammatory reflex. J. Leukoc. Biol. 83:512-517.
68. Oke SL, Tracey KJ (2009). The inflammatory reflex and the role of complementary and alternative medical therapies. Ann. NY Acad. Sci. 1172:172-180.
69. Oschman J. Recent developments in bioelectromagnetic medicine. In: Rosch PJ, Markov MS, editors. Bioelectromagnetic medicine. New York: Marcel Dekker; (2004). pp 77-92.
70. Pan X, Yu X, Qin L, Zhang P (2010). "Old drugs" for the treatment of rheumatoid arthritis: will the cholinergic anti-inflammatory pathway and anti-nociceptive pathway work Inflamm. Res. 59: 1005-1007.
71. Pan XH, Zhang J, Yu X, Qin L, Kang L, Zhang P (2010). New therapeutic approaches for the treatment of rheumatoid arthritis may rise from the cholinergic anti-inflammatory pathway and antinociceptive pathway. ScientificWorldJournal 10:2248-2253.
72. Pavlov VA, Wang H, Czura CJ, Friedman SG, Tracey KJ (2003). The cholinergic anti-inflammatory pathway: A missing link in neuroimmunomodulation. Mol. Med. 9:125-134.
73. Pokorny J, Vedruccio C, Cifra M, Kucera O (2011). Cancer physics: diagnostics based on damped cellular elastoelectrical vibrations in microtubules. Eur. Biophys. J. 40:747-759.
74. Porges SW (2003). The Polyvagal theory: phylogenetic contributions to social behavior. Physiol. Behav. 79: 503-513.
75. Proctor ML, Smith CA, Farquhar CM, Stones RW (2002). Transcutaneous electrical nerve stimulation and acupuncture for primary dysmenorrhoea. Cochrane Database Syst. Rev. 1:CD002123.
76. Raja SN, Meyer RA, Ringkamp M, Campbell JN. Peripheral neural mechanisms of nociception. In: Wall PD, Melzack R, editors. Textbook of pain. Edinburgh: Churchill Livingston; (1999). pp 11-57.
77. Rosch PJ (2009). Bioelectromagnetic and subtle energy medicine: The interface between mind and matter. Ann. NY Acad. Sci. 1172:297-311.
78. Sandkuhler J. Lang-lasting analgesia following TENS and acupuncture: spinal mechanisms beyond gate control. In: Devor M, Rowbotham MC, Hallin ZW, editors. The 9th World Congress on Pain, Progress in Pain Research and Management. Vienna: IASP Press; (1999). pp 359-369.
79. Sandkuhler J, Chen JG, Cheng G, Randić M (1997). Low-frequency stimulation of afferent Adelta-fibers induces long-term depression at primary afferent synapses with substantia gelatinosa neurons in the rat. J. Neurosci. 17:6483-6491.
80. Schepper LD (2006). Achieving and maintaining the simillimum. New Delhi: B Jain Publishers.
81. Schiepers OJ, Wichers MC, Maes M (2005). Cytokines and major depression. Prog. Neuropsychopharmacol. Biol. Psychiatry 29:201-217.
82. Schwacha MG, Chaudry IH (2002). The cellular basis of post-burn immunosuppression: macrophages and mediators. Int. J. Mol. Med. 10:239-243.
83. Senekowitsch F, Endler PC, Pongratz W, Smith CW (1995). Hormone effects by CD record/replay. FASEB J. 9:A392.
84. Shahabi S (2006). Evaluation of the effect of post-burn heating on healing of burned skin and burn-induced immunosuppression in Balb/c mice. Tehran: Tarbiat Modarres University.
85. Shahabi S, Hashemi M, Hassan ZM, Javan M, Bathaie SZ, Toraihi T, Zakeri Z, et al. (2006). The effect of post-burn local hyperthermia on the reducing burn injury: The possible role of opioids. Int. J. Hyperthermia 22:421-431.
86. Shahabi S, Hassan ZM, Jazani NH (2009). Post heat shock tolerance: A neuroimmunological antiinflammatory phenomenon. J. Inflamm. (Lond.) 6:7.
87. Siegel A, Zalcman SS, editors (2008). The neuroimmunological basis of behavior and mental disorders. New York: Springer.
88. Simko M, Mattsson MO (2004). Extremely low frequency electromagnetic fields as effectors of cellular responses in vitro: possible immune cell activation. J. Cell Biochem. 93:83-92.
89. Slawinska D, Polewski K (1992). The stress-induced electromagnetic emission from biosystems: chemiluminescence response of plants to mechanical and chemical damage. Bioelectrochem. Bioenerg. 28:483-488.
90. Slawinski J (2005). Photon emission from perturbed and dying organisms: biomedical perspectives. Forsch. Komplementarmed. Klass. Naturheilkd. 12:90-95.
91. Slawinski J, Ezzahir A, Godlewski M, Kwiecinska T, Rajfur Z, Sitko D, Wierzuchowska D (1992). Stressinduced photon emission from perturbed organisms. Experientia 48:1041-1058.
92. Sluka KA, Vance CG, Lisi TL (2005). High-frequency, but not low-frequency, transcutaneous electrical nerve stimulation reduces aspartate and glutamate release in the spinal cord dorsal horn. J. Neurochem. 95:1794-1801.
93. Sonnier H, Marino AA (2001). Sensory transduction as a proposed model for biological detection of electromagnetic fields. Electromagn. Biol. Med. 20:153-175.
94. Sternberg EM (1997). Neural-immune interactions in health and disease. J. Clin. Invest. 100:2641-2647.
95. Sternberg EM, Hill JM, Chrousos GP, Kamilaris T, Listwak SJ, Gold PW, Wilder RL (1989). Inflammatory mediator-induced hypothalamic-pituitary-adrenal axis activation is defective in streptococcal cell wall arthritis-susceptible Lewis rats. Proc. Natl. Acad. Sci. U.S.A. 86:2374-2378.
96. Swayne J (2000). International dictionary of homeopathy. Edinburgh: Churchill Livingstone.
97. Thomas Y, Schiff M, Belkadi L, Jurgens P, Kahhak L, Benveniste J (2000). Activation of human neutrophils by electronically transmitted phorbol-myristate acetate. Med. Hypotheses 54:33-39.
98. Tracey KJ (2002). The inflammatory reflex. Nature 420:853-859.
99. Tracey KJ (2005). Fat meets the cholinergic antiinflammatory pathway. J. Exp. Med. 202:1017-1021.
100. Tracey KJ (2007). Physiology and immunology of the cholinergic antiinflammatory pathway. J. Clin. Invest. 117:289-296.
101. Van Wijk R, Van Wijk EP, Wiegant FA, Ives J (2008). Free radicals and low-level photon emission in human pathogenesis: state of the art. Indian J. Exp. Biol. 46:273-309.
102. Vianale G, Reale M, Amerio P, Stefanachi M, Di Luzio S, Muraro R (2008). Extremely low frequency electromagnetic field enhances human keratinocyte cell growth and decreases proinflammatory chemokine production. Br. J. Dermatol. 158:1189-1196.
103. Watkins LR, Maier SF (1999). Implications of immune-to-brain communication for sickness and pain. Proc. Natl. Acad. Sci. U.S.A. 96:7710-7713.
104. Wolf FI, Torsello A, Tedesco B, Fasanella S, Boninsegna A, D'Ascenzo M, Grassi C, et al. (2005). 50-Hz extremely low frequency electromagnetic fields enhance cell proliferation and DNA damage: possible involvement of a redox mechanism. Biochim. Biophys. Acta 1743:120-129.
105. Xiong J, Xue FS, Yuan YJ, Wang Q, Liao X, Wang WL (2010). Cholinergic anti-inflammatory pathway: A possible approach to protect against myocardial ischemia reperfusion injury. Chin. Med. J. (Engl.) 123: 2720-2726.
106. Zabara J, Chaffee Jr, RB, Tansy MF (1972). Neuroinhibition in the regulation of emesis. Space Life Sci. 3: 282-292.
107. Zhang M, Borovikova LV, Wang H, Metz C, Tracey KJ (1999). Spermine inhibition of monocyte activation and inflammation. Mol. Med. 5:595-605.