Antitumor activity of two gelsemine metabolites in rat liver microsomes

Journal of Asian Natural Products Research

Volumn 12, Issue 9, 2010, Pages 731-739

  Zhao, Qing Chun ^a   Hua, Wei ^a   Zhang, Lin ^a   Guo, Tao ^a   Zhao, Ming Hong ^a   Yan, Ming ^a   Shi, Guo Bing ^a   Wu, Li Jun ^a  

^a SHENYANG NORTHERN HOSPITAL   (China)

Author keywords

21 oxogelsemine; 4 N demethylgelsemine; antitumor; gelsemine; liver microsomes

Indexed keywords

21 OXOGELSEMINE; 4 NORGELSEMINE; ALKALOID; DRUG METABOLITE; GELSEMINE; PHENOBARBITAL; PLANT EXTRACT; SILICA GEL; UNCLASSIFIED DRUG; 21-OXOGELSEMINE; 4-N-DEMETHYLGELSEMINE; ANTINEOPLASTIC AGENT;

ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ARTICLE; CELL STRAIN HEPG2; CONTROLLED STUDY; DRUG ISOLATION; GELSEMIUM; HELA CELL; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN TISSUE; IN VITRO STUDY; LIVER MICROSOME; MASS SPECTROMETRY; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; RAT; ANIMAL; CHEMICAL STRUCTURE; CHEMISTRY; DRUG EFFECTS; DRUG SCREENING; HELA CELL LINE; HEPG2 CELL LINE; ISOLATION AND PURIFICATION; METABOLISM; NUCLEAR MAGNETIC RESONANCE; SPRAGUE DAWLEY RAT;

GELSEMIUM ELEGANS; RATTUS;

ALKALOIDS; ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DRUG SCREENING ASSAYS, ANTITUMOR; GELSEMIUM; HELA CELLS; HEP G2 CELLS; HUMANS; MICROSOMES, LIVER; MOLECULAR STRUCTURE; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; RATS; RATS, SPRAGUE-DAWLEY;

EID: 77956625775     PISSN: 10286020     EISSN: 14772213     Source Type: Journal    
DOI: 10.1080/10286020.2010.492951     Document Type: Article

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