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Volumn 8, Issue 3, 2013, Pages 220-234

Patents on brain permeable nanoparticles

Author keywords

Blood brain barrier; Nanoparticles; Neurotherapeutics; Neurotoxicity; Patents; Polymeric nanoparticles

Indexed keywords

CENTRAL NERVOUS SYSTEM AGENTS; CYANOACRYLATE DERIVATIVE; NANOPARTICLE; POLYGLACTIN; POLYLACTIC ACID; POLYMER; PRODRUG; SOLVENT;

EID: 84892545161     PISSN: 15748898     EISSN: None     Source Type: Journal    
DOI: 10.2174/1574889808666131128105141     Document Type: Article
Times cited : (6)

References (203)
  • 1
    • 21344451667 scopus 로고    scopus 로고
    • Colloidal carriers and blood-brain barrier (BBB) translocation: A way to deliver drugs to the brain
    • Garcia-Garcia E, Andrieux K, Gil S, Couvreur P. Colloidal carriers and blood-brain barrier (BBB) translocation: A way to deliver drugs to the brain. Int J Pharm 2005; 298: 274-92.
    • (2005) Int J Pharm , vol.298 , pp. 274-292
    • Garcia-Garcia, E.1    Andrieux, K.2    Gil, S.3    Couvreur, P.4
  • 3
    • 0034794883 scopus 로고    scopus 로고
    • Restricted transport of anti-transferrin receptor antibody (OX26) through the blood-brain barrier in the rat
    • Moos T, Morgan EH. Restricted transport of anti-transferrin receptor antibody (OX26) through the blood-brain barrier in the rat. J Neurochem 2001; 79: 119-29.
    • (2001) J Neurochem , vol.79 , pp. 119-129
    • Moos, T.1    Morgan, E.H.2
  • 5
    • 0033526158 scopus 로고    scopus 로고
    • Recent advances in the brain targeting of neuropharmaceuticals by chemical delivery systems
    • Bodor N, Buchwald P. Recent advances in the brain targeting of neuropharmaceuticals by chemical delivery systems. Adv Drug Deliv Rev 1999; 36: 229-54.
    • (1999) Adv Drug Deliv Rev , vol.36 , pp. 229-254
    • Bodor, N.1    Buchwald, P.2
  • 6
    • 0033526186 scopus 로고    scopus 로고
    • The blood-brain barrier efflux transporters as a detoxifying system for the brain
    • Terasaki T, Hosoya K. The blood-brain barrier efflux transporters as a detoxifying system for the brain. Adv Drug Deliv Rev 1999; 36: 195-209.
    • (1999) Adv Drug Deliv Rev , vol.36 , pp. 195-209
    • Terasaki, T.1    Hosoya, K.2
  • 7
    • 27744599588 scopus 로고    scopus 로고
    • Targeted nanoparticles for drug delivery through the blood-brain barrier for Alzheimer's disease
    • Roney C, Kulkarni P, Arora V, Antich P, Bonte F, Wu A et al. Targeted nanoparticles for drug delivery through the blood-brain barrier for Alzheimer's disease. J Control Release 2005; 108: 193-214.
    • (2005) J Control Release , vol.108 , pp. 193-214
    • Roney, C.1    Kulkarni, P.2    Arora, V.3    Antich, P.4    Bonte, F.5    Wu, A.6
  • 8
    • 77949851032 scopus 로고    scopus 로고
    • Blood Brain Barriers: Smuggling Past the Barricades
    • Chivukula V, Chhabria MT. Blood Brain Barriers: Smuggling Past the Barricades. Ind J Pharm Sci 2004; 66: 259-64.
    • (2004) Ind J Pharm Sci , vol.66 , pp. 259-264
    • Chivukula, V.1    Chhabria, M.T.2
  • 9
    • 0023835077 scopus 로고
    • Chemotherapy for malignant gliomas
    • Kornblith PL, Walker M. Chemotherapy for malignant gliomas. J Neurosurg 1988; 68: 1-17.
    • (1988) J Neurosurg , vol.68 , pp. 1-17
    • Kornblith, P.L.1    Walker, M.2
  • 10
    • 24644474375 scopus 로고    scopus 로고
    • Drug delivery across the bloodbrain barrier
    • Chen Y, Dalwadi G, Benson HAE. Drug delivery across the bloodbrain barrier. Curr Drug Deliv 2004; 1: 361-76.
    • (2004) Curr Drug Deliv , vol.1 , pp. 361-376
    • Chen, Y.1    Dalwadi, G.2    Benson, H.A.E.3
  • 11
    • 34347387938 scopus 로고    scopus 로고
    • Strategies to improve drug delivery across the blood-brain barrier
    • De Boer AG, Gaillard PJ. Strategies to improve drug delivery across the blood-brain barrier. Clin Pharmacokinet 2007; 46: 553-76.
    • (2007) Clin Pharmacokinet , vol.46 , pp. 553-576
    • De Boer, A.G.1    Gaillard, P.J.2
  • 12
    • 0021346836 scopus 로고
    • Modification of the blood-brain-barrier and the chemotherapy of malignant brain tumors
    • Neuwelt EA, Rapoport SI. Modification of the blood-brain-barrier and the chemotherapy of malignant brain tumors. Fed Proc 1984; 43: 214-19.
    • (1984) Fed Proc , vol.43 , pp. 214-219
    • Neuwelt, E.A.1    Rapoport, S.I.2
  • 13
    • 0032504604 scopus 로고    scopus 로고
    • Central analgesic actions of loperamide following transient permeation of the blood-brain barrier with Cereport (RMP-7)
    • Emerich DF, Snodgrass P, Pink M, Bloom F, Bartus RT. Central analgesic actions of loperamide following transient permeation of the blood-brain barrier with Cereport (RMP-7). Brain Res 1998; 801: 259-66.
    • (1998) Brain Res , vol.801 , pp. 259-266
    • Emerich, D.F.1    Snodgrass, P.2    Pink, M.3    Bloom, F.4    Bartus, R.T.5
  • 16
    • 0025315810 scopus 로고
    • Arecoline, but not haloperidol, induces changes in the permeability of the blood-brain barrier in the rat
    • Saija A, Princi P, De Pasquale A, Costa G. Arecoline, but not haloperidol, induces changes in the permeability of the blood-brain barrier in the rat. J Pharm Pharmacol 1990; 42: 135-8.
    • (1990) J Pharm Pharmacol , vol.42 , pp. 135-138
    • Saija, A.1    Princi, P.2    De Pasquale, A.3    Costa, G.4
  • 21
    • 0035074592 scopus 로고    scopus 로고
    • The development of the bradykinin agonist labradimil as a means to increase the permeability of the blood-brain barrier: From concept to clinical evaluation
    • Emerich DF, Dean RL, Osborn C, Bartus RT. The development of the bradykinin agonist labradimil as a means to increase the permeability of the blood-brain barrier: From concept to clinical evaluation. Clin Pharmacokinet 2001; 40: 105-23.
    • (2001) Clin Pharmacokinet , vol.40 , pp. 105-123
    • Emerich, D.F.1    Dean, R.L.2    Osborn, C.3    Bartus, R.T.4
  • 22
    • 0033962411 scopus 로고    scopus 로고
    • Inflammatory mediators and modulation of blood-brain barrier permeability
    • Abbott NJ. Inflammatory mediators and modulation of blood-brain barrier permeability. Cellular Mol Neurobiol 2000; 20:131-47.
    • (2000) Cellular Mol Neurobiol , vol.20 , pp. 131-147
    • Abbott, N.J.1
  • 30
    • 0141620181 scopus 로고    scopus 로고
    • Peptide transport and delivery into the central nervous system
    • In: Prokai, L, Prokai-Tatrai K, Eds, Birkhauser Verlag
    • Begley D, Brightman MW. In: Prokai, L, Prokai-Tatrai K, Eds. Peptide transport and delivery into the central nervous system. Progress in drug research. Birkhauser Verlag 2003: 39-78.
    • (2003) Progress in drug research , pp. 39-78
    • Begley, D.1    Brightman, M.W.2
  • 31
    • 1642536206 scopus 로고    scopus 로고
    • Brain-targeted drug delivery: Experiences to date
    • Bodor N, Buchwald P. Brain-targeted drug delivery: Experiences to date. Am J Drug Targ 2003; 1:13-26.
    • (2003) Am J Drug Targ , vol.1 , pp. 13-26
    • Bodor, N.1    Buchwald, P.2
  • 32
    • 1642454475 scopus 로고    scopus 로고
    • ABC transporters and the blood-brain barrier
    • Begley D. ABC transporters and the blood-brain barrier. Curr Pharm Design 2004; 10:1295-312.
    • (2004) Curr Pharm Design , vol.10 , pp. 1295-1312
    • Begley, D.1
  • 33
    • 0021346836 scopus 로고
    • Modification of the blood-brain-barrier and the chemotherapy of malignant brain tumors
    • Neuwelt EA, Rapoport SI. Modification of the blood-brain-barrier and the chemotherapy of malignant brain tumors. Fed Proc 1984; 43: 214-19.
    • (1984) Fed Proc , vol.43 , pp. 214-219
    • Neuwelt, E.A.1    Rapoport, S.I.2
  • 34
    • 0343724706 scopus 로고    scopus 로고
    • Prodrugs for improved CNS delivery
    • Anderson BD. Prodrugs for improved CNS delivery. Adv Drug Deliv Rev 1996; 19: 171-202.
    • (1996) Adv Drug Deliv Rev , vol.19 , pp. 171-202
    • Anderson, B.D.1
  • 35
    • 0035114794 scopus 로고    scopus 로고
    • A prodrug of NMDA/glycine site antagonist, L-703,717 with improved BBB permeability: 4-Acetoxy derivative and its positronemitter labeled analog
    • Haradahira T, Zhang MR, Maeda J, Okauchi T, Kida T, Kawabe K et al. A prodrug of NMDA/glycine site antagonist, L-703,717 with improved BBB permeability: 4-Acetoxy derivative and its positronemitter labeled analog. Chem Pharm Bull 2001; 49:147-50.
    • (2001) Chem Pharm Bull , vol.49 , pp. 147-150
    • Haradahira, T.1    Zhang, M.R.2    Maeda, J.3    Okauchi, T.4    Kida, T.5    Kawabe, K.6
  • 48
    • 0029874655 scopus 로고    scopus 로고
    • Increasing volume of distribution to the brain with interstitial infusion: Dose, rather than convection, might be the most important factor
    • Kroll RA, Pagel MA, Muldoon LL, Roman GS, Neuwelt EA. Increasing volume of distribution to the brain with interstitial infusion: Dose, rather than convection, might be the most important factor. Neurosurg 1996; 38: 752-4.
    • (1996) Neurosurg , vol.38 , pp. 752-754
    • Kroll, R.A.1    Pagel, M.A.2    Muldoon, L.L.3    Roman, G.S.4    Neuwelt, E.A.5
  • 49
    • 0036812216 scopus 로고    scopus 로고
    • Trafficking of intracerebroventricularly injected antisense oligonucleotides in the mouse brain
    • Chauhan NB. Trafficking of intracerebroventricularly injected antisense oligonucleotides in the mouse brain. Nucl Acid Drug Dev 2002; 12: 353-7.
    • (2002) Nucl Acid Drug Dev , vol.12 , pp. 353-357
    • Chauhan, N.B.1
  • 52
    • 14644431736 scopus 로고    scopus 로고
    • Cerebral edema associated with Gliadel wafers: Two case studies
    • Weber EL, Goebel EA. Cerebral edema associated with Gliadel wafers: Two case studies. Neuro-oncol 2005; 7: 84-9.
    • (2005) Neuro-oncol , vol.7 , pp. 84-89
    • Weber, E.L.1    Goebel, E.A.2
  • 53
    • 0035821406 scopus 로고    scopus 로고
    • Prolonged hypoglycemic effect of insulin-loaded polybutylcyanoacrylate nanoparticles after pulmonary administration to normal rats
    • Zhang Q, Shen Z, Nagai T. Prolonged hypoglycemic effect of insulin-loaded polybutylcyanoacrylate nanoparticles after pulmonary administration to normal rats. Int J Pharm 2001; 218: 75-80.
    • (2001) Int J Pharm , vol.218 , pp. 75-80
    • Zhang, Q.1    Shen, Z.2    Nagai, T.3
  • 54
    • 0037459005 scopus 로고    scopus 로고
    • Nasal drug delivery-possibilities, problems and solutions
    • Illum L. Nasal drug delivery-possibilities, problems and solutions. J Control Release 2003; 87: 187-98.
    • (2003) J Control Release , vol.87 , pp. 187-198
    • Illum, L.1
  • 55
    • 0031740593 scopus 로고    scopus 로고
    • Nasal route for direct delivery of solutes to the central nervous system: Fact or fiction?
    • Mathison S, Nagilla R, Kompella UB. Nasal route for direct delivery of solutes to the central nervous system: Fact or fiction? J Drug Target 1998; 5: 415-41.
    • (1998) J Drug Target , vol.5 , pp. 415-441
    • Mathison, S.1    Nagilla, R.2    Kompella, U.B.3
  • 56
    • 0000517316 scopus 로고
    • Drainage of cerebral interstitial fluid into deep cervical lymph of the rabbit
    • Bradbury MW, Cserr HF, Westrop RJ. Drainage of cerebral interstitial fluid into deep cervical lymph of the rabbit. Am J Physiol 1981; 240: F329-36.
    • (1981) Am J Physiol , vol.240 , pp. 329-336
    • Bradbury, M.W.1    Cserr, H.F.2    Westrop, R.J.3
  • 57
    • 0025944792 scopus 로고
    • The transport of a drug to the cerebrospinal fluid directly from the nasal cavity: The relation to the lipophilicity of the drug
    • Sakane T, Akizuki M, Yamashita S, Nadai T, Hashida M, Sezaki H. The transport of a drug to the cerebrospinal fluid directly from the nasal cavity: The relation to the lipophilicity of the drug. Chem Pharm Bull 1991; 39: 2456-8.
    • (1991) Chem Pharm Bull , vol.39 , pp. 2456-2458
    • Sakane, T.1    Akizuki, M.2    Yamashita, S.3    Nadai, T.4    Hashida, M.5    Sezaki, H.6
  • 60
    • 2942706032 scopus 로고    scopus 로고
    • Intranasal delivery: An approach to bypass the blood brain barrier
    • Talegaonkar S, Mishra PR. Intranasal delivery: An approach to bypass the blood brain barrier. Ind J Pharmacol 2004; 36: 140-7.
    • (2004) Ind J Pharmacol , vol.36 , pp. 140-147
    • Talegaonkar, S.1    Mishra, P.R.2
  • 61
    • 0033956526 scopus 로고    scopus 로고
    • Biomaterials in drug delivery and tissue engineering: One laboratory's experience
    • Langer R. Biomaterials in drug delivery and tissue engineering: One laboratory's experience. Acc Chem Res 2000; 33: 94-101.
    • (2000) Acc Chem Res , vol.33 , pp. 94-101
    • Langer, R.1
  • 68
    • 12344262085 scopus 로고    scopus 로고
    • Drug transport to brain with targeted liposomes
    • Schynder A, Huwyler J. Drug transport to brain with targeted liposomes. NeuroRx 2005; 2: 99-107.
    • (2005) NeuroRx , vol.2 , pp. 99-107
    • Schynder, A.1    Huwyler, J.2
  • 73
    • 8344223879 scopus 로고    scopus 로고
    • Lipid mediated transport and carrier mediated transport of small molecules
    • Cambridge University Press
    • Pardridge WM. Lipid mediated transport and carrier mediated transport of small molecules. In: Drug targeting: The future of brain drug. Cambridge University Press. 2001; 36-81.
    • (2001) Drug targeting: The future of brain drug , pp. 36-81
    • Pardridge, W.M.1
  • 75
    • 0033956526 scopus 로고    scopus 로고
    • Biomaterials in drug delivery and tissue engineering: One laboratory's experience
    • Langer R. Biomaterials in drug delivery and tissue engineering: One laboratory's experience. Acc Chem Res 2000; 33: 94-101.
    • (2000) Acc Chem Res , vol.33 , pp. 94-101
    • Langer, R.1
  • 76
  • 77
    • 30544446478 scopus 로고    scopus 로고
    • Long-circulating polymeric nanovectors for tumor-selective gene delivery
    • Kommareddy S, Tiwari SB, Amiji MM. Long-circulating polymeric nanovectors for tumor-selective gene delivery. Technol Cancer Res Treat 2005; 4: 615-25.
    • (2005) Technol Cancer Res Treat , vol.4 , pp. 615-625
    • Kommareddy, S.1    Tiwari, S.B.2    Amiji, M.M.3
  • 78
    • 17644395943 scopus 로고    scopus 로고
    • Polyethylene glycol-conjugated copolymers for plasmid DNA delivery
    • Lee M, Kim SW. Polyethylene glycol-conjugated copolymers for plasmid DNA delivery. Pharm Res 2005; 22: 1-10.
    • (2005) Pharm Res , vol.22 , pp. 1-10
    • Lee, M.1    Kim, S.W.2
  • 79
    • 0000812919 scopus 로고
    • Nanoparticles
    • In Kreuter J, Ed, Marcel Dekker
    • Kreuter J. Nanoparticles. In Kreuter J, Ed. Colloidal drug delivery systems, Marcel Dekker 1994: 219-342.
    • (1994) Colloidal drug delivery systems , pp. 219-342
    • Kreuter, J.1
  • 80
    • 29144504424 scopus 로고    scopus 로고
    • Nanomaterials and supercritical fluids
    • Reverchon E, Adami R. Nanomaterials and supercritical fluids. J Supercrit Fluids 2006; 37: 1-22.
    • (2006) J Supercrit Fluids , vol.37 , pp. 1-22
    • Reverchon, E.1    Adami, R.2
  • 82
    • 29244456217 scopus 로고    scopus 로고
    • Poly (lactic acid) nanoparticles for sustained release of budesonide
    • Kompella UB, Bandi N, Ayalasomayajula SP. Poly (lactic acid) nanoparticles for sustained release of budesonide. Drug Deliv Technol 2001; 1: 1-7.
    • (2001) Drug Deliv Technol , vol.1 , pp. 1-7
    • Kompella, U.B.1    Bandi, N.2    Ayalasomayajula, S.P.3
  • 83
    • 0347761356 scopus 로고    scopus 로고
    • Preparation an characterization of cationic PLGA nanospheres as DNA carriers
    • Ravi MN, Bakowsky U, Lehr CM. Preparation an characterization of cationic PLGA nanospheres as DNA carriers. Biomat 2004; 25: 1771-7.
    • (2004) Biomat , vol.25 , pp. 1771-1777
    • Ravi, M.N.1    Bakowsky, U.2    Lehr, C.M.3
  • 84
    • 0035962385 scopus 로고    scopus 로고
    • PEGylated polycyanoacrylate nanoparticles as tumor necrosis factor-[alpha] carriers
    • Li YP, Pei YY, Zhou ZH, Zhang XY, Gu ZH, Ding J, et al. PEGylated polycyanoacrylate nanoparticles as tumor necrosis factor-[alpha] carriers. J Control Release 2001; 71: 287-96.
    • (2001) J Control Release , vol.71 , pp. 287-296
    • Li, Y.P.1    Pei, Y.Y.2    Zhou, Z.H.3    Zhang, X.Y.4    Gu, Z.H.5    Ding, J.6
  • 86
    • 0032472391 scopus 로고    scopus 로고
    • Influence of experimental parameters on the characteristics of poly (lactic acid) nanoparticles prepared by double emulsion method
    • Zambaux MF, Bonneaux F, Gref R, Maincent P, Dellacherie E, Alonso MJ, et al. Influence of experimental parameters on the characteristics of poly (lactic acid) nanoparticles prepared by double emulsion method. J Control Release 1998; 50: 31-40.
    • (1998) J Control Release , vol.50 , pp. 31-40
    • Zambaux, M.F.1    Bonneaux, F.2    Gref, R.3    Maincent, P.4    Dellacherie, E.5    Alonso, M.J.6
  • 87
    • 0027155794 scopus 로고
    • Preparation of biodegradable nanoparticles of water-soluble and insoluble drugs with D, Llactide/ glycolide copolymer by a novel spontaneous emulsification solvent diffusion method, and the drug release behavior
    • Niwa T, Takeuchi H, Hino T, Kunou N, Kawashima Y. Preparation of biodegradable nanoparticles of water-soluble and insoluble drugs with D, Llactide/ glycolide copolymer by a novel spontaneous emulsification solvent diffusion method, and the drug release behavior. J Control Release 1993; 25: 89-98.
    • (1993) J Control Release , vol.25 , pp. 89-98
    • Niwa, T.1    Takeuchi, H.2    Hino, T.3    Kunou, N.4    Kawashima, Y.5
  • 88
    • 0035821406 scopus 로고    scopus 로고
    • Prolonged hypoglycemic effect of insulin-loaded polybutylcyanoacrylate nanoparticles after pulmonary administration to normal rats
    • Zhang Q, Shen Z, Nagai T. Prolonged hypoglycemic effect of insulin-loaded polybutylcyanoacrylate nanoparticles after pulmonary administration to normal rats. Int J Pharm 2001; 218: 75-80.
    • (2001) Int J Pharm , vol.218 , pp. 75-80
    • Zhang, Q.1    Shen, Z.2    Nagai, T.3
  • 89
    • 0035821412 scopus 로고    scopus 로고
    • Combined hydroxypropyl-[beta]-cyclodextrin and poly(alkylcyanoacrylate) nanoparticles intended for oral administration of saquinavir
    • Boudad H, Legrand P, Lebas G, Cheron M, Duchene D, Ponchel G. Combined hydroxypropyl-[beta]-cyclodextrin and poly(alkylcyanoacrylate) nanoparticles intended for oral administration of saquinavir. Int J Pharm 2001; 218: 113-24.
    • (2001) Int J Pharm , vol.218 , pp. 113-124
    • Boudad, H.1    Legrand, P.2    Lebas, G.3    Cheron, M.4    Duchene, D.5    Ponchel, G.6
  • 90
    • 0028791550 scopus 로고
    • Influence of the preparation conditions on poly(ethylcyanoacrylate) nanocapsule formation
    • Puglisi G, Fresta M, Giammona G, Ventura CA. Influence of the preparation conditions on poly(ethylcyanoacrylate) nanocapsule formation. Int J Pharm 1995; 125: 283-87.
    • (1995) Int J Pharm , vol.125 , pp. 283-287
    • Puglisi, G.1    Fresta, M.2    Giammona, G.3    Ventura, C.A.4
  • 91
    • 0031550212 scopus 로고    scopus 로고
    • Novel hydrophilic chitosan-polyethylene oxide nanoprticles as protein carriers
    • Calvo P, Remunan-Lopez C, Vila-Jato JL, Alonso MJ. Novel hydrophilic chitosan-polyethylene oxide nanoprticles as protein carriers. J Appl Polymer Sci 1997; 63: 125-32.
    • (1997) J Appl Polymer Sci , vol.63 , pp. 125-132
    • Calvo, P.1    Remunan-Lopez, C.2    Vila-Jato, J.L.3    Alonso, M.J.4
  • 92
    • 0030779190 scopus 로고    scopus 로고
    • Chitosan and chitosan/ethylene oxide-propylene oxide block copolymer nanoparticles as novel carriers for proteins and vaccines
    • Calvo P, Remunan-Lopez C, Vila-Jato JL, Alonso MJ. Chitosan and chitosan/ethylene oxide-propylene oxide block copolymer nanoparticles as novel carriers for proteins and vaccines. Pharm Res 1997; 14: 1431-6.
    • (1997) Pharm Res , vol.14 , pp. 1431-1436
    • Calvo, P.1    Remunan-Lopez, C.2    Vila-Jato, J.L.3    Alonso, M.J.4
  • 93
    • 0034964315 scopus 로고    scopus 로고
    • Particle design using supercritical fluids: Literature and patent survey
    • Jung J, Perrut M. Particle design using supercritical fluids: Literature and patent survey. J Supercritic Fluids 2001; 20: 179-219.
    • (2001) J Supercritic Fluids , vol.20 , pp. 179-219
    • Jung, J.1    Perrut, M.2
  • 94
    • 33745017344 scopus 로고    scopus 로고
    • Formation of nanoparticles of a hydrophilic drug using supercritical carbon dioxide and microencapsulation for sustained release
    • Thote AJ, Gupta RB. Formation of nanoparticles of a hydrophilic drug using supercritical carbon dioxide and microencapsulation for sustained release. Nanomedicine: Nanotech Biol Med 2005; 1: 85-90.
    • (2005) Nanomedicine: Nanotech Biol Med , vol.1 , pp. 85-90
    • Thote, A.J.1    Gupta, R.B.2
  • 95
    • 0020615103 scopus 로고
    • Pharmacokinetics and distribution of a biodegradable drug carrier
    • Grislain L, Couvrer P, Lenaerts V. Pharmacokinetics and distribution of a biodegradable drug carrier. Int J Pharm 1983; 15: 333-45.
    • (1983) Int J Pharm , vol.15 , pp. 333-345
    • Grislain, L.1    Couvrer, P.2    Lenaerts, V.3
  • 96
    • 0030448509 scopus 로고    scopus 로고
    • Nanoparticles and micro particles for drug and vaccine delivery
    • Kreuter J. Nanoparticles and micro particles for drug and vaccine delivery. J Anat 1996; 189: 503-5.
    • (1996) J Anat , vol.189 , pp. 503-505
    • Kreuter, J.1
  • 97
    • 0025300990 scopus 로고
    • Modification of the body distribution of poly (methyl methyl methylacrylate) nanoparticles by coating with surfactants
    • Troster SD, Muller U, Kreuter J. Modification of the body distribution of poly (methyl methyl methylacrylate) nanoparticles by coating with surfactants. Int J Pharm 1990; 61: 85-100.
    • (1990) Int J Pharm , vol.61 , pp. 85-100
    • Troster, S.D.1    Muller, U.2    Kreuter, J.3
  • 102
    • 0033427851 scopus 로고    scopus 로고
    • Indirect evidence that drug brain targeting using polysorbate 80-coated polybutylcyanoacrylate nanoparticles is related to toxicity
    • Olivier JC, Fenart L, Chauvet R, Pariat C, Cecchelli R, Couet W. Indirect evidence that drug brain targeting using polysorbate 80-coated polybutylcyanoacrylate nanoparticles is related to toxicity. Pharm Res 1999; 16: 1836-42.
    • (1999) Pharm Res , vol.16 , pp. 1836-1842
    • Olivier, J.C.1    Fenart, L.2    Chauvet, R.3    Pariat, C.4    Cecchelli, R.5    Couet, W.6
  • 105
    • 0023242385 scopus 로고
    • Biodistribution of poly (butyl 2-cyanoacrylate) nanoparticles in rabbits
    • Douglas SJ, Davis SS, Illum L. Biodistribution of poly (butyl 2-cyanoacrylate) nanoparticles in rabbits. Int J Pharm 1986; 34: 145-52.
    • (1986) Int J Pharm , vol.34 , pp. 145-152
    • Douglas, S.J.1    Davis, S.S.2    Illum, L.3
  • 106
    • 0023232633 scopus 로고
    • Localization of colloidal particles (liposomes, hexylcyanoacrylate nanoparticles and albumin nanoparticles) by histology and autoradiography in mice
    • Waser PG, Muller U, Kreuter S, Munz K, Kaiser E, Pfluger B. Localization of colloidal particles (liposomes, hexylcyanoacrylate nanoparticles and albumin nanoparticles) by histology and autoradiography in mice. Int J Pharm 1987; 39: 213-27.
    • (1987) Int J Pharm , vol.39 , pp. 213-227
    • Waser, P.G.1    Muller, U.2    Kreuter, S.3    Munz, K.4    Kaiser, E.5    Pfluger, B.6
  • 107
    • 0023907683 scopus 로고
    • Tissue distribution of polybutylcyanoacrylate nanoparticles carrying spin-labelled nitrosourea
    • Simeonova M, Ivanova T, Raikova E, Georgieva M, Raikov Z. Tissue distribution of polybutylcyanoacrylate nanoparticles carrying spin-labelled nitrosourea. Int J Pharm 1988; 43: 267-71.
    • (1988) Int J Pharm , vol.43 , pp. 267-271
    • Simeonova, M.1    Ivanova, T.2    Raikova, E.3    Georgieva, M.4    Raikov, Z.5
  • 108
  • 109
    • 0032472296 scopus 로고    scopus 로고
    • Body distribution of azidothymidine bound to hexyl-cyanoacrylate nanoparticles after i.v. injection to rats
    • Lobenberg R, Araujo L, von Briesen H, Rodgers E, Kreuter J. Body distribution of azidothymidine bound to hexyl-cyanoacrylate nanoparticles after i.v. injection to rats. J Control Release 1998; 50: 21-30.
    • (1998) J Control Release , vol.50 , pp. 21-30
    • Lobenberg, R.1    Araujo, L.2    von Briesen, H.3    Rodgers, E.4    Kreuter, J.5
  • 112
    • 0030993566 scopus 로고    scopus 로고
    • Delivery of loperamide across the blood-brain barrier with polysorbate 80-coated polybutylcyanoacrylate nanoparticles
    • Alyautdin RN, Petrov VE, Langer K, Berthold A, Kharkevich DA, Kreuter J. Delivery of loperamide across the blood-brain barrier with polysorbate 80-coated polybutylcyanoacrylate nanoparticles. Pharm Res 1997; 14: 325-8.
    • (1997) Pharm Res , vol.14 , pp. 325-328
    • Alyautdin, R.N.1    Petrov, V.E.2    Langer, K.3    Berthold, A.4    Kharkevich, D.A.5    Kreuter, J.6
  • 114
    • 0035937595 scopus 로고    scopus 로고
    • Nanoparticulate systems for brain delivery of drugs
    • Kreuter J. Nanoparticulate systems for brain delivery of drugs. Adv Drug Deliv Rev 2001; 47: 65-81.
    • (2001) Adv Drug Deliv Rev , vol.47 , pp. 65-81
    • Kreuter, J.1
  • 115
    • 0031281885 scopus 로고    scopus 로고
    • Kinetics of blood component adsorption on poly(D, L-lactic acid) nanoparticles: Evidence of complement C3 component involvement
    • Allemann E, Gravel P, Leroux JC, Balant L, Gurny R. Kinetics of blood component adsorption on poly(D, L-lactic acid) nanoparticles: Evidence of complement C3 component involvement. J Biomed Mater Res 1997; 37: 229-34.
    • (1997) J Biomed Mater Res , vol.37 , pp. 229-234
    • Allemann, E.1    Gravel, P.2    Leroux, J.C.3    Balant, L.4    Gurny, R.5
  • 116
    • 0343191443 scopus 로고    scopus 로고
    • 'Stealth' corona-core nanoparticles surface modified by polyethylene glycol (PEG): Influences of the corona (PEG chain length and surface density) and of the core composition on phagocytic up take and plasma protein adsorption
    • Gref R, Lück M, Quellec P, Marchand M, Dellacherie E, Harnisch S. 'Stealth' corona-core nanoparticles surface modified by polyethylene glycol (PEG): Influences of the corona (PEG chain length and surface density) and of the core composition on phagocytic up take and plasma protein adsorption. Colloids Surfaces: Biointerfaces B 2000; 18: 301-13.
    • (2000) Colloids Surfaces: Biointerfaces B , vol.18 , pp. 301-313
    • Gref, R.1    Lück, M.2    Quellec, P.3    Marchand, M.4    Dellacherie, E.5    Harnisch, S.6
  • 117
    • 0034750955 scopus 로고    scopus 로고
    • Influence of surface-modifying surfactants on the pharmacokinetic behavior of 14C-poly(methylmethacrylate) nanoparticles in experimental tumor models
    • Lode J, Fichtner I, Kreuter J, Berndt A, Diederichs JE, Reszka R. Influence of surface-modifying surfactants on the pharmacokinetic behavior of 14C-poly(methylmethacrylate) nanoparticles in experimental tumor models. Pharm Res 2001; 18: 1613-19.
    • (2001) Pharm Res , vol.18 , pp. 1613-1619
    • Lode, J.1    Fichtner, I.2    Kreuter, J.3    Berndt, A.4    Diederichs, J.E.5    Reszka, R.6
  • 118
    • 0033807852 scopus 로고    scopus 로고
    • Influence of nanoparticles on the brain-to-serum distribution and the metabolism of valproic acid in mice
    • Darius J, Meyer FP, Sabel BA, Schroeder U. Influence of nanoparticles on the brain-to-serum distribution and the metabolism of valproic acid in mice. J Pharm Pharmacol 2000; 52: 1043-7.
    • (2000) J Pharm Pharmacol , vol.52 , pp. 1043-1047
    • Darius, J.1    Meyer, F.P.2    Sabel, B.A.3    Schroeder, U.4
  • 119
    • 0033649767 scopus 로고    scopus 로고
    • Body distribution of 3Hlabelled dalargin bound to poly (butyl cyanoacrylate) nanoparticles after i.v. injections to mice
    • Schroeder U, Schroeder H, Sabel BA. Body distribution of 3Hlabelled dalargin bound to poly (butyl cyanoacrylate) nanoparticles after i.v. injections to mice. Life Sci 2000; 66: 495-502.
    • (2000) Life Sci , vol.66 , pp. 495-502
    • Schroeder, U.1    Schroeder, H.2    Sabel, B.A.3
  • 120
    • 0034812929 scopus 로고    scopus 로고
    • Long-circulating PEGylated polycyanoacrylate nanoparticles as new drug carrier for brain delivery
    • Calvo PP, Gouritin B, Chacun H, Desmaële D, D'Angelo J, Noel JP et al. Long-circulating PEGylated polycyanoacrylate nanoparticles as new drug carrier for brain delivery. Pharm Res 2001; 18: 1157-66.
    • (2001) Pharm Res , vol.18 , pp. 1157-1166
    • Calvo, P.P.1    Gouritin, B.2    Chacun, H.3    Desmaële, D.4    D'Angelo, J.5    Noel, J.P.6
  • 121
    • 0021966380 scopus 로고
    • The distribution and elimination of methotrexate in mouse blood and brain after concurrent administration of polysorbate 80
    • Azmin MN, Stuart JF, Florence AT. The distribution and elimination of methotrexate in mouse blood and brain after concurrent administration of polysorbate 80. Cancer Chemother Pharmacol 1985; 14: 238-42.
    • (1985) Cancer Chemother Pharmacol , vol.14 , pp. 238-242
    • Azmin, M.N.1    Stuart, J.F.2    Florence, A.T.3
  • 122
    • 0033993565 scopus 로고    scopus 로고
    • Increase of the duration of the anticonvulsive activity of a novel NMDA receptor antagonist using poly (butylcyanoacrylate) nanoparticles as a parenteral controlled release system
    • Friese A, Seiller E, Quack G, Lorenz B, Kreuter J. Increase of the duration of the anticonvulsive activity of a novel NMDA receptor antagonist using poly (butylcyanoacrylate) nanoparticles as a parenteral controlled release system. Eur J Pharm Biopharm 2000; 49: 103-09.
    • (2000) Eur J Pharm Biopharm , vol.49 , pp. 103-109
    • Friese, A.1    Seiller, E.2    Quack, G.3    Lorenz, B.4    Kreuter, J.5
  • 123
    • 0032580450 scopus 로고    scopus 로고
    • Something new in the field of PLA/GA bioresorbable polymers
    • Vert M, Schwach G, Engel R, Coudane J. Something new in the field of PLA/GA bioresorbable polymers. J Control Release 1998; 53: 85-92.
    • (1998) J Control Release , vol.53 , pp. 85-92
    • Vert, M.1    Schwach, G.2    Engel, R.3    Coudane, J.4
  • 124
    • 0343247711 scopus 로고    scopus 로고
    • Biodegradation and biocompatibility of PLA and PLGA microspheres
    • Anderson JM, Shive MS. Biodegradation and biocompatibility of PLA and PLGA microspheres. Adv Drug Deliv Rev 1997; 28: 5-24.
    • (1997) Adv Drug Deliv Rev , vol.28 , pp. 5-24
    • Anderson, J.M.1    Shive, M.S.2
  • 125
    • 0032976670 scopus 로고    scopus 로고
    • Hydrolytic degradation characteristics of aliphatic polyesters derived from lactic and glycolic acids
    • Li S. Hydrolytic degradation characteristics of aliphatic polyesters derived from lactic and glycolic acids. J Biomed Mater Res 1999; 48: 342-53.
    • (1999) J Biomed Mater Res , vol.48 , pp. 342-353
    • Li, S.1
  • 126
    • 0031429762 scopus 로고    scopus 로고
    • Erosion of biodegradable block copolymers made of poly(D, L-lactic acid) and poly-(ethylene glycol)
    • Von Burkersroda F, Gref R, Gopferich A. Erosion of biodegradable block copolymers made of poly(D, L-lactic acid) and poly-(ethylene glycol). Biomat 1997; 18: 1599-607.
    • (1997) Biomat , vol.18 , pp. 1599-1607
    • Von Burkersroda, F.1    Gref, R.2    Gopferich, A.3
  • 127
    • 0032188874 scopus 로고    scopus 로고
    • Protein encapsulation within polyethylene glycol-coated nanospheres. I. Physicochemical characterization
    • Quellec P, Gref R, Perrin L, Dellacherie E, Sommer F, Verbavatz JM, et al. Protein encapsulation within polyethylene glycol-coated nanospheres. I. Physicochemical characterization. J Biomed Mater Res 1998; 42: 45-54.
    • (1998) J Biomed Mater Res , vol.42 , pp. 45-54
    • Quellec, P.1    Gref, R.2    Perrin, L.3    Dellacherie, E.4    Sommer, F.5    Verbavatz, J.M.6
  • 128
    • 0030209082 scopus 로고    scopus 로고
    • Effect of PEO surface density on long-circulating PLA-PEO nanoparticles which are very low complement activators
    • Vittaz M, Bazile D, Spenlehauer G, Verrecchia T, Veillard M, Puisieux F, et al. Effect of PEO surface density on long-circulating PLA-PEO nanoparticles which are very low complement activators. Biomaterials 1996; 17: 1575-81.
    • (1996) Biomaterials , vol.17 , pp. 1575-1581
    • Vittaz, M.1    Bazile, D.2    Spenlehauer, G.3    Verrecchia, T.4    Veillard, M.5    Puisieux, F.6
  • 129
    • 0033527924 scopus 로고    scopus 로고
    • Protein encapsulation within polyethylene glycol-coated nanospheres. II. Controlled release properties
    • Quellec P, Gref R, Dellacherie E, Sommer F, Tran MD, Alonso MJ. Protein encapsulation within polyethylene glycol-coated nanospheres. II. Controlled release properties. J Biomed Mater Res 1999; 47: 388-95.
    • (1999) J Biomed Mater Res , vol.47 , pp. 388-395
    • Quellec, P.1    Gref, R.2    Dellacherie, E.3    Sommer, F.4    Tran, M.D.5    Alonso, M.J.6
  • 130
    • 0035808245 scopus 로고    scopus 로고
    • Protein C-loaded monomethoxypoly (ethylene oxide)-poly(lactic acid) nanoparticles
    • Zambaux MF, Bonneaux F, Gref R, Dellacherie E, Vigneron C. Protein C-loaded monomethoxypoly (ethylene oxide)-poly(lactic acid) nanoparticles. Int J Pharm 2001; 212: 1-9.
    • (2001) Int J Pharm , vol.212 , pp. 1-9
    • Zambaux, M.F.1    Bonneaux, F.2    Gref, R.3    Dellacherie, E.4    Vigneron, C.5
  • 131
    • 0347170869 scopus 로고    scopus 로고
    • Safety of poly (ethylene glycol) and poly (ethylene glycol) derivatives. In: Poly (ethylene glycol): Chemistry and biological applications ACS Symposium Series
    • Working PK, Newman MS, Johnson J, Cornacoff JB. Safety of poly (ethylene glycol) and poly (ethylene glycol) derivatives. In: Poly (ethylene glycol): chemistry and biological applications ACS Symposium Series. American Chemical Society 1997; 680: 45-57.
    • (1997) American Chemical Society , vol.680 , pp. 45-57
    • Working, P.K.1    Newman, M.S.2    Johnson, J.3    Cornacoff, J.B.4
  • 132
    • 0030298086 scopus 로고    scopus 로고
    • Stability study of nanoparticles of poly(epsiloncaprolactone), poly(D, L-lactide) and poly (D, L-lactide-coglycolide)
    • Lemoine D, Francois C, Kedzierewicz F, Preat V, Hoffman M, Maincent P. Stability study of nanoparticles of poly(epsiloncaprolactone), poly(D, L-lactide) and poly (D, L-lactide-coglycolide). Biomat 1996; 17: 2191-7.
    • (1996) Biomat , vol.17 , pp. 2191-2197
    • Lemoine, D.1    Francois, C.2    Kedzierewicz, F.3    Preat, V.4    Hoffman, M.5    Maincent, P.6
  • 133
    • 0032851387 scopus 로고    scopus 로고
    • Comparison of the safety profiles of PLA50 and Me. PEG-PLA50 nanoparticles after single dose intravenous administration to rat
    • Plard JP, Didier B. Comparison of the safety profiles of PLA50 and Me. PEG-PLA50 nanoparticles after single dose intravenous administration to rat. Colloids Surfaces B: Biointerfaces 1999; 16: 173-83.
    • (1999) Colloids Surfaces B: Biointerfaces , vol.16 , pp. 173-183
    • Plard, J.P.1    Didier, B.2
  • 134
    • 0028116078 scopus 로고
    • Surface modification of poly (lactide-co-glycolide) nanospheres by biodegradable poly(lactide)-poly(ethylene glycol) copolymers
    • Stolnik S, Dunn SE, Garnett MC, Davies MC, Coombes AG, Taylor DC, et al. Surface modification of poly (lactide-co-glycolide) nanospheres by biodegradable poly(lactide)-poly(ethylene glycol) copolymers. Pharm Res 1994; 11: 1800-8.
    • (1994) Pharm Res , vol.11 , pp. 1800-1808
    • Stolnik, S.1    Dunn, S.E.2    Garnett, M.C.3    Davies, M.C.4    Coombes, A.G.5    Taylor, D.C.6
  • 135
    • 0029091362 scopus 로고
    • Non-stealth (poly(lactic acid/albumin) and stealth (poly(lactic acid-polyethylene glycol) nanoparticles as injectable drug carriers
    • Verrecchia T, Spenlehauer G, Bazile DV, Murry-Brelier A, Archimbaud Y, Veillard M. Non-stealth (poly(lactic acid/albumin) and stealth (poly(lactic acid-polyethylene glycol) nanoparticles as injectable drug carriers. J Control Release 1995; 36: 49-61.
    • (1995) J Control Release , vol.36 , pp. 49-61
    • Verrecchia, T.1    Spenlehauer, G.2    Bazile, D.V.3    Murry-Brelier, A.4    Archimbaud, Y.5    Veillard, M.6
  • 136
    • 0028203956 scopus 로고
    • Fate of [14C] poly (-lactide-co-glycolide) nanoparticles after intravenous and oral administration to mice
    • Le Ray AM, Vert M, Gautier JC, Benoi{dotless}̂t JP. Fate of [14C] poly (-lactide-co-glycolide) nanoparticles after intravenous and oral administration to mice. Int J Pharm 1994; 106: 201-11.
    • (1994) Int J Pharm , vol.106 , pp. 201-211
    • Le Ray, A.M.1    Vert, M.2    Gautier, J.C.3    Benoît, J.P.4
  • 137
    • 0035795022 scopus 로고    scopus 로고
    • PEGylated PLGA nanoparticles as protein carriers: Synthesis, preparation and biodistribution in rats
    • Li Y, Pei Y, Zhang X, Gu Z, Zhou Z, Yuan W, et al. PEGylated PLGA nanoparticles as protein carriers: Synthesis, preparation and biodistribution in rats. J Control Release 2001; 71: 203-11.
    • (2001) J Control Release , vol.71 , pp. 203-211
    • Li, Y.1    Pei, Y.2    Zhang, X.3    Gu, Z.4    Zhou, Z.5    Yuan, W.6
  • 138
    • 0034996764 scopus 로고    scopus 로고
    • Long-circulating and targetspecific nanoparticles: Theory to practice
    • Moghimi SM, Hunter AC, Murray JC. Long-circulating and targetspecific nanoparticles: Theory to practice. Pharmacol Rev 2001; 53: 283-318.
    • (2001) Pharmacol Rev , vol.53 , pp. 283-318
    • Moghimi, S.M.1    Hunter, A.C.2    Murray, J.C.3
  • 139
    • 0031081070 scopus 로고    scopus 로고
    • Interactions of poly(lactic acid) and poly(lactic acid-co-ethylene oxide) nanoparticles with the plasma factors of the coagulation system
    • Sahli H, Tapon-Bretaudière J, Fischer AM, Sternberg C, Spenlehauer G, Verrecchia T, et al. Interactions of poly(lactic acid) and poly(lactic acid-co-ethylene oxide) nanoparticles with the plasma factors of the coagulation system. Biomat 1997; 18: 281-88.
    • (1997) Biomat , vol.18 , pp. 281-288
    • Sahli, H.1    Tapon-Bretaudière, J.2    Fischer, A.M.3    Sternberg, C.4    Spenlehauer, G.5    Verrecchia, T.6
  • 141
    • 0034017403 scopus 로고    scopus 로고
    • Involvement of neutrophilic granulocytes in the uptake of biodegradable non-stealth and stealth nanoparticles in guinea pig
    • Zambaux MF, Faivre-Fiorina B, Bonneau F, Marchal S, Merlin JL, Dellacherie E, et al. Involvement of neutrophilic granulocytes in the uptake of biodegradable non-stealth and stealth nanoparticles in guinea pig. Biomat 2000; 21: 975-80.
    • (2000) Biomat , vol.21 , pp. 975-980
    • Zambaux, M.F.1    Faivre-Fiorina, B.2    Bonneau, F.3    Marchal, S.4    Merlin, J.L.5    Dellacherie, E.6
  • 143
    • 84886946569 scopus 로고    scopus 로고
    • Image guided drug delivery to the brain using nanotechnology
    • doi: 10.1016/j.drudis.2013.06.010. [Epub ahead of print]
    • Ding H, Wu F, Nair MP. Image guided drug delivery to the brain using nanotechnology. Drug Discov Today 2013; doi: 10.1016/j.drudis.2013.06.010. [Epub ahead of print].
    • (2013) Drug Discov Today
    • Ding, H.1    Wu, F.2    Nair, M.P.3
  • 145
    • 77955466238 scopus 로고    scopus 로고
    • Nanoparticle-mediated brain-specific drug delivery, imaging, and diagnosis
    • Yang H. Nanoparticle-mediated brain-specific drug delivery, imaging, and diagnosis. Pharm Res 2010; 27: 1759-71.
    • (2010) Pharm Res , vol.27 , pp. 1759-1771
    • Yang, H.1
  • 146
    • 84886311462 scopus 로고    scopus 로고
    • Nanoparticles for Brain Drug Delivery
    • Article ID 238428
    • Masserini M. Nanoparticles for Brain Drug Delivery. ISRN Biochemistry 2013; 2013: Article ID 238428, 18.
    • (2013) ISRN Biochemistry 2013 , pp. 18
    • Masserini, M.1
  • 147
    • 79959790434 scopus 로고    scopus 로고
    • Neurotoxicity of silica nanoparticles: Brain localization and dopaminergic neurons damage pathways
    • Wu J, Wang C, Sun J, Xue Y. Neurotoxicity of silica nanoparticles: Brain localization and dopaminergic neurons damage pathways. ACS Nano 2011; 5: 4476-89.
    • (2011) ACS Nano , vol.5 , pp. 4476-4489
    • Wu, J.1    Wang, C.2    Sun, J.3    Xue, Y.4
  • 148
    • 84880287247 scopus 로고    scopus 로고
    • Molecular mechanism of titanium dioxide nanoparticles-induced oxidative injury in the brain of mice
    • Ze Y, Zheng L, Zhao X, Gui S, Sang X, Su J, et al. Molecular mechanism of titanium dioxide nanoparticles-induced oxidative injury in the brain of mice. Chemosphere 2013; 92:1183-9.
    • (2013) Chemosphere , vol.92 , pp. 1183-1189
    • Ze, Y.1    Zheng, L.2    Zhao, X.3    Gui, S.4    Sang, X.5    Su, J.6
  • 150
    • 84555220669 scopus 로고    scopus 로고
    • In vivo specific delivery of c-Met siRNA to glioblastoma using cationic solid lipid nanoparticles
    • Jin J, Bae KH, Yang H, Lee SJ, Kim H, Kim Y, et al. In vivo specific delivery of c-Met siRNA to glioblastoma using cationic solid lipid nanoparticles. Bioconjugate Chemistry 2011; 22: 2568-72.
    • (2011) Bioconjugate Chemistry , vol.22 , pp. 2568-2572
    • Jin, J.1    Bae, K.H.2    Yang, H.3    Lee, S.J.4    Kim, H.5    Kim, Y.6
  • 151
    • 0036001387 scopus 로고    scopus 로고
    • Pharmaceutical strategies utilizing recombinant human serum albumin
    • Chuang VTG, Kragh-Hansen U, Otagiri M. Pharmaceutical strategies utilizing recombinant human serum albumin. Pharm Res 2002; 19: 569-77.
    • (2002) Pharm Res , vol.19 , pp. 569-577
    • Chuang, V.T.G.1    Kragh-Hansen, U.2    Otagiri, M.3
  • 152
    • 77649192717 scopus 로고    scopus 로고
    • Efficacy of surface charge in targeting pegylated nanoparticles of sulpiride to the brain
    • Parikh T, Bommana MM, Squillante E. Efficacy of surface charge in targeting pegylated nanoparticles of sulpiride to the brain. Eur J Pharm Biopharm 2010; 74: 442-50.
    • (2010) Eur J Pharm Biopharm , vol.74 , pp. 442-450
    • Parikh, T.1    Bommana, M.M.2    Squillante, E.3
  • 153
    • 84868482671 scopus 로고    scopus 로고
    • Protective effects of cationic bovine serum albumin-conjugated PEGylated tanshinone IIA nanoparticles on cerebral ischemia
    • Liu X, An C, Jin P, Liu X, Wang L. Protective effects of cationic bovine serum albumin-conjugated PEGylated tanshinone IIA nanoparticles on cerebral ischemia. Biomat 2013; 34: 817-30.
    • (2013) Biomat , vol.34 , pp. 817-830
    • Liu, X.1    An, C.2    Jin, P.3    Liu, X.4    Wang, L.5
  • 154
    • 50849094554 scopus 로고    scopus 로고
    • TAT-conjugated nanoparticles for the CNS delivery of anti HIV drugs
    • Rao KS, Reddy MK, Horning JL, Labhasetwar V. TAT-conjugated nanoparticles for the CNS delivery of anti HIV drugs. Biomat 2008; 29: 4429-38.
    • (2008) Biomat , vol.29 , pp. 4429-4438
    • Rao, K.S.1    Reddy, M.K.2    Horning, J.L.3    Labhasetwar, V.4
  • 155
    • 34249895458 scopus 로고    scopus 로고
    • Trans-activating transcriptional activator (TAT) peptide-mediated brain drug delivery
    • Rao KS, Labhasetwar V. Trans-activating transcriptional activator (TAT) peptide-mediated brain drug delivery. J Biomed Nanotech 2006; 2: 173-85.
    • (2006) J Biomed Nanotech , vol.2 , pp. 173-185
    • Rao, K.S.1    Labhasetwar, V.2
  • 156
    • 58149185965 scopus 로고    scopus 로고
    • Polymeric micelles anchored with TAT for delivery of antibiotics across the blood brain barrier
    • Liu L, Venkatraman SS, Yang YY, Guo K, Lu J, He B, et al. Polymeric micelles anchored with TAT for delivery of antibiotics across the blood brain barrier. Biopolym 2008; 90: 617-23.
    • (2008) Biopolym , vol.90 , pp. 617-623
    • Liu, L.1    Venkatraman, S.S.2    Yang, Y.Y.3    Guo, K.4    Lu, J.5    He, B.6
  • 157
    • 80054814424 scopus 로고    scopus 로고
    • Efficacy of CG (3) R (6) TAT nanoparticles self-assembled from a novel antimicrobial peptide for the treatment of Candida albicans meningitis in rabbits
    • Xu K, Wang H, Liu L, Xu W, Sheng J, Fan W, et al. Efficacy of CG (3) R (6) TAT nanoparticles self-assembled from a novel antimicrobial peptide for the treatment of Candida albicans meningitis in rabbits. Chemoth 2011; 57: 417-25.
    • (2011) Chemoth , vol.57 , pp. 417-425
    • Xu, K.1    Wang, H.2    Liu, L.3    Xu, W.4    Sheng, J.5    Fan, W.6
  • 158
    • 84865778361 scopus 로고    scopus 로고
    • Penetratinfunctionalized PEGPLA nanoparticles for brain drug delivery
    • Xia H, Gao X, Gu G, Liu Z, Hu Q, Tu Y, et al. Penetratinfunctionalized PEGPLA nanoparticles for brain drug delivery. Int J Pharmacol 2012; 436: 840-50.
    • (2012) Int J Pharmacol , vol.436 , pp. 840-850
    • Xia, H.1    Gao, X.2    Gu, G.3    Liu, Z.4    Hu, Q.5    Tu, Y.6
  • 159
    • 77955640333 scopus 로고    scopus 로고
    • Polymeric carriers for gene delivery: Chitosan and poly (amidoamine) dendrimers
    • Xu Q, Wang CH, Pack DW. Polymeric carriers for gene delivery: Chitosan and poly (amidoamine) dendrimers. Curr Pharm Design 2010; 16: 2350-68.
    • (2010) Curr Pharm Design , vol.16 , pp. 2350-2368
    • Xu, Q.1    Wang, C.H.2    Pack, D.W.3
  • 160
    • 84864933593 scopus 로고    scopus 로고
    • OX26 modified hyper branched polyglycerol-conjugated poly (lactic-co-glycolic acid) nanoparticles: Synthesis, characterization and evaluation of its brain delivery ability
    • Bao H, Jin X, Li L, Lv F, Liu T. OX26 modified hyper branched polyglycerol-conjugated poly (lactic-co-glycolic acid) nanoparticles: synthesis, characterization and evaluation of its brain delivery ability. J Mater Sci 2012; 23: 1891-901.
    • (2012) J Mater Sci , vol.23 , pp. 1891-1901
    • Bao, H.1    Jin, X.2    Li, L.3    Lv, F.4    Liu, T.5
  • 161
    • 84864313094 scopus 로고    scopus 로고
    • Delivery of gold nanoparticles to the brain by conjugation with a peptide that recognizes the transferrin receptor
    • Prades R, Guerrero S, Araya E, Molina C, Salas E, Zurita E, et al. Delivery of gold nanoparticles to the brain by conjugation with a peptide that recognizes the transferrin receptor. Biomat 2012; 33: 7194-205.
    • (2012) Biomat , vol.33 , pp. 7194-7205
    • Prades, R.1    Guerrero, S.2    Araya, E.3    Molina, C.4    Salas, E.5    Zurita, E.6
  • 162
  • 163
    • 70449441249 scopus 로고    scopus 로고
    • A nanomedicine transports a peptide caspase-3 inhibitor across the blood-brain barrier and provides neuroprotection
    • Karatas H, Aktas Y, Gursoy-Ozdemir Y, Bodur E, Yemisci M, Caban S, et al. A nanomedicine transports a peptide caspase-3 inhibitor across the blood-brain barrier and provides neuroprotection. J Neurosci 2009; 29: 13761-9.
    • (2009) J Neurosci , vol.29 , pp. 13761-13769
    • Karatas, H.1    Aktas, Y.2    Gursoy-Ozdemir, Y.3    Bodur, E.4    Yemisci, M.5    Caban, S.6
  • 164
    • 0029009048 scopus 로고
    • Human insulin receptor monoclonal antibody undergoes high affinity binding to human brain capillaries in vitro and rapid transcytosis through the blood-brain barrier in vivo in the primate
    • Pardridge WM, Kang YS, Buciak JL, Yang J. Human insulin receptor monoclonal antibody undergoes high affinity binding to human brain capillaries in vitro and rapid transcytosis through the blood-brain barrier in vivo in the primate. Pharm Res 1995; 12: 807-16.
    • (1995) Pharm Res , vol.12 , pp. 807-816
    • Pardridge, W.M.1    Kang, Y.S.2    Buciak, J.L.3    Yang, J.4
  • 165
    • 60549085837 scopus 로고    scopus 로고
    • Physiological pathway for low-density lipoproteins across the blood-brain barrier: Transcytosis through brain capillary endothelial cells in vitro
    • Candela P, Gosselet F, Miller F, Buee-Scherrer V, Torpier G, Cecchelli R, et al. Physiological pathway for low-density lipoproteins across the blood-brain barrier: Transcytosis through brain capillary endothelial cells in vitro. Endothelium 2008; 15: 254-64.
    • (2008) Endothelium , vol.15 , pp. 254-264
    • Candela, P.1    Gosselet, F.2    Miller, F.3    Buee-Scherrer, V.4    Torpier, G.5    Cecchelli, R.6
  • 166
    • 84862790727 scopus 로고    scopus 로고
    • A dual-targeting nano carrier based on poly (amidoamine) dendrimers conjugated with transferrin and tamoxifen for treating brain gliomas
    • Li Y, He H, Jia X, Lu WL, Lou J, Wei Y. A dual-targeting nano carrier based on poly (amidoamine) dendrimers conjugated with transferrin and tamoxifen for treating brain gliomas. Biomat 2012; 33: 3899-908.
    • (2012) Biomat , vol.33 , pp. 3899-3908
    • Li, Y.1    He, H.2    Jia, X.3    Lu, W.L.4    Lou, J.5    Wei, Y.6
  • 167
    • 18744413936 scopus 로고    scopus 로고
    • Polysorbate-stabilized solid lipid nanoparticles as colloidal carriers for intravenous targeting of drugs to the brain: Comparison of plasma protein adsorption patterns
    • Goppert TM, Muller RH. Polysorbate-stabilized solid lipid nanoparticles as colloidal carriers for intravenous targeting of drugs to the brain: Comparison of plasma protein adsorption patterns. J Drug Target 2005; 13: 179-87.
    • (2005) J Drug Target , vol.13 , pp. 179-187
    • Goppert, T.M.1    Muller, R.H.2
  • 169
    • 79960297652 scopus 로고    scopus 로고
    • Enhanced brain targeting of temozolomide in polysorbate-80 coated polybutylcyanoacrylate nanoparticles
    • Xin HT, Xiao NL, Feng W, Wei F, Zhi CH, Peng W, et al. Enhanced brain targeting of temozolomide in polysorbate-80 coated polybutylcyanoacrylate nanoparticles. Int J Nanomed 2011; 6: 445-52.
    • (2011) Int J Nanomed , vol.6 , pp. 445-452
    • Xin, H.T.1    Xiao, N.L.2    Feng, W.3    Wei, F.4    Zhi, C.H.5    Peng, W.6
  • 170
    • 33947630376 scopus 로고    scopus 로고
    • Translocation of poly (ethylene glycol-co-hexadecyl) cyanoacrylate nanoparticles into rat brain endothelial cells: Role of apolipoproteins on receptor-medicted endocytosis
    • Kim HR, Andrieux K, Gil S, Taverna M, Chacun H, Desmaële D, et al. Translocation of poly (ethylene glycol-co-hexadecyl) cyanoacrylate nanoparticles into rat brain endothelial cells: Role of apolipoproteins on receptor-medicted endocytosis. Biomacromolecules 2007; 8: 793-9.
    • (2007) Biomacromolecules , vol.8 , pp. 793-799
    • Kim, H.R.1    Andrieux, K.2    Gil, S.3    Taverna, M.4    Chacun, H.5    Desmaële, D.6
  • 171
    • 80053209371 scopus 로고    scopus 로고
    • Functionalization of liposomes with ApoE-derived peptides at different density affects cellular uptake and drug transport across a blood-brain barrier model
    • Re F, Cambianica I, Zona C, Sesana S, Gregori M, Rigolio R, et al. Functionalization of liposomes with ApoE-derived peptides at different density affects cellular uptake and drug transport across a blood-brain barrier model. Nanomedicine NBM 2011; 7: 551-9.
    • (2011) Nanomedicine NBM , vol.7 , pp. 551-559
    • Re, F.1    Cambianica, I.2    Zona, C.3    Sesana, S.4    Gregori, M.5    Rigolio, R.6
  • 172
    • 70350200866 scopus 로고    scopus 로고
    • Gene delivery targeted to the brain using an Angiopep-conjugated polyethylene glycol-modified polyamidoamine dendrimer
    • Ke W, Shao K, Huang R, Han L, Liu Y, Li J, et al. Gene delivery targeted to the brain using an Angiopep-conjugated polyethylene glycol-modified polyamidoamine dendrimer. Biomat 2009; 30: 6976-85.
    • (2009) Biomat , vol.30 , pp. 6976-6985
    • Ke, W.1    Shao, K.2    Huang, R.3    Han, L.4    Liu, Y.5    Li, J.6
  • 174
    • 69249209818 scopus 로고    scopus 로고
    • Characterization of endocytosis of transferrin-coated PLGA nanoparticles by the blood-brain barrier
    • Chang J, Jallouli Y, Kroubi M, Yuan XB, Feng W, Kang CS, et al. Characterization of endocytosis of transferrin-coated PLGA nanoparticles by the blood-brain barrier. Int J Pharm 2009; 379: 285-92.
    • (2009) Int J Pharm , vol.379 , pp. 285-292
    • Chang, J.1    Jallouli, Y.2    Kroubi, M.3    Yuan, X.B.4    Feng, W.5    Kang, C.S.6
  • 175
    • 84865340231 scopus 로고    scopus 로고
    • Comparative receptor based brain delivery of tramadolloaded poly (lacticco-glycolic acid) nanoparticles
    • Lalani J, Raichandani Y, Mathur R, Lalan M, Chutani K, Mishra AK, et al. Comparative receptor based brain delivery of tramadolloaded poly (lacticco-glycolic acid) nanoparticles. J Biomed Nanotech 2012; 8: 918-27.
    • (2012) J Biomed Nanotech , vol.8 , pp. 918-927
    • Lalani, J.1    Raichandani, Y.2    Mathur, R.3    Lalan, M.4    Chutani, K.5    Mishra, A.K.6
  • 176
    • 59649102668 scopus 로고    scopus 로고
    • Transferrin-and transferrin-receptor-antibody-modified nanoparticles enable drug delivery across the blood-brain barrier (BBB)
    • Ulbrich K, Hekmatara T, Herbert E, Kreuter J. Transferrin-and transferrin-receptor-antibody-modified nanoparticles enable drug delivery across the blood-brain barrier (BBB). Eur J Pharm Biopharm 2009; 71: 251-6.
    • (2009) Eur J Pharm Biopharm , vol.71 , pp. 251-256
    • Ulbrich, K.1    Hekmatara, T.2    Herbert, E.3    Kreuter, J.4
  • 177
    • 33750597937 scopus 로고    scopus 로고
    • MR imaging of relapsing multiple sclerosis patients using ultra-small-particle iron oxide and compared with gadolinium
    • Dousset V, Brochet B, Deloire MS, Lagoarde L, Barroso B, Caille JM, et al. MR imaging of relapsing multiple sclerosis patients using ultra-small-particle iron oxide and compared with gadolinium. Americ J Neuroradiol 2006; 27: 1000-5.
    • (2006) Americ J Neuroradiol , vol.27 , pp. 1000-1005
    • Dousset, V.1    Brochet, B.2    Deloire, M.S.3    Lagoarde, L.4    Barroso, B.5    Caille, J.M.6
  • 178
    • 32944464860 scopus 로고    scopus 로고
    • An exploratory study of ferumoxtran-10 nanoparticles as a blood-brain barrier imaging agent targeting phagocytic cells in CNS inflammatory lesions
    • Manninger SP, Muldoon LL, Nesbit G, Murillo T, Jacobs PM, Neuwelt EA. An exploratory study of ferumoxtran-10 nanoparticles as a blood-brain barrier imaging agent targeting phagocytic cells in CNS inflammatory lesions. Americ J Neuroradiol 2005; 26: 2290-300.
    • (2005) Americ J Neuroradiol , vol.26 , pp. 2290-2300
    • Manninger, S.P.1    Muldoon, L.L.2    Nesbit, G.3    Murillo, T.4    Jacobs, P.M.5    Neuwelt, E.A.6
  • 179
    • 27544515520 scopus 로고    scopus 로고
    • In vivo detection of developing vessel occlusion in photothrombotic ischemic brain lesions in the rat by iron particle enhanced MRI
    • Kleinschnitz C, Schütz A, Nölte I, Horn T, Frank M, Solymosi L et al. In vivo detection of developing vessel occlusion in photothrombotic ischemic brain lesions in the rat by iron particle enhanced MRI. J Cereb Blood Flow Metabol 2005; 25: 1548-55.
    • (2005) J Cereb Blood Flow Metabol , vol.25 , pp. 1548-1555
    • Kleinschnitz, C.1    Schütz, A.2    Nölte, I.3    Horn, T.4    Frank, M.5    Solymosi, L.6
  • 180
    • 0034764183 scopus 로고    scopus 로고
    • Dynamic patterns of USPIO enhancement can be observed in macrophages after ischemic brain damage
    • Rausch M, Sauter A, Frohlich J, Neubacher U, Radu EW, Rudin M, Dynamic patterns of USPIO enhancement can be observed in macrophages after ischemic brain damage. Magn Reson Med 2001; 46:1018-22.
    • (2001) Magn Reson Med , vol.46 , pp. 1018-1022
    • Rausch, M.1    Sauter, A.2    Frohlich, J.3    Neubacher, U.4    Radu, E.W.5    Rudin, M.6
  • 181
    • 0035986054 scopus 로고    scopus 로고
    • In-vivo visualization of phagocytotic cells in rat brains after transient ischemia by USPIO
    • Rausch M, Baumann D, Neubacher U, Rudin M, In-vivo visualization of phagocytotic cells in rat brains after transient ischemia by USPIO. NMR Biomed 2002; 15: 278-83.
    • (2002) NMR Biomed , vol.15 , pp. 278-283
    • Rausch, M.1    Baumann, D.2    Neubacher, U.3    Rudin, M.4
  • 182
    • 3142560811 scopus 로고    scopus 로고
    • Histochemical detection of ultra-small super paramagnetic iron oxide (USPIO) contrast medium uptake in experimental brain ischemia
    • Schroeter M, Saleh A, Wiedermann D, Hoehn M, Jander S, Histochemical detection of ultra-small super paramagnetic iron oxide (USPIO) contrast medium uptake in experimental brain ischemia. Magn Reson Med 2004; 52: 403-6.
    • (2004) Magn Reson Med , vol.52 , pp. 403-406
    • Schroeter, M.1    Saleh, A.2    Wiedermann, D.3    Hoehn, M.4    Jander, S.5
  • 183
    • 60749134708 scopus 로고    scopus 로고
    • Effective trans vascular delivery of nanoparticles across the blood-brain tumor barrier into malignant glioma cells
    • Sarin H, Kanevsky AS, Wu H, Brimacombe KR, Fung SH, Sousa AA et al. Effective trans vascular delivery of nanoparticles across the blood-brain tumor barrier into malignant glioma cells. J Transl Med 2008; 6: 80.
    • (2008) J Transl Med , vol.6 , pp. 80
    • Sarin, H.1    Kanevsky, A.S.2    Wu, H.3    Brimacombe, K.R.4    Fung, S.H.5    Sousa, A.A.6
  • 184
    • 83955165727 scopus 로고    scopus 로고
    • Size and surface charge of gold nanoparticles determine absorption across intestinal barriers and accumulation in secondary target organs after oral administration
    • Schleh C, Semmler-Behnke M, Lipka J, Wenk A, Hirn S, Schäffler M et al. Size and surface charge of gold nanoparticles determine absorption across intestinal barriers and accumulation in secondary target organs after oral administration. Nanotoxicol 2012; 6: 36-46.
    • (2012) Nanotoxicol , vol.6 , pp. 36-46
    • Schleh, C.1    Semmler-Behnke, M.2    Lipka, J.3    Wenk, A.4    Hirn, S.5    Schäffler, M.6
  • 185
    • 67649205803 scopus 로고    scopus 로고
    • The potential for nanoparticle-based drug delivery to the brain: Overcoming the blood-brain barrier
    • Barbu E, Molnar E, Tsibouklis J, Gorecki DC, The potential for nanoparticle-based drug delivery to the brain: overcoming the blood-brain barrier. Expert Opin Drug Deliv 2009; 6: 553-65.
    • (2009) Expert Opin Drug Deliv , vol.6 , pp. 553-565
    • Barbu, E.1    Molnar, E.2    Tsibouklis, J.3    Gorecki, D.C.4
  • 186
    • 84862646346 scopus 로고    scopus 로고
    • Designing the nanoparticle-biomolecule interface for targeting and therapeutic delivery
    • Mahon E, Salvati A, Bombelli FB, Lynch I, Dawson KA, Designing the nanoparticle-biomolecule interface for targeting and therapeutic delivery. J Control Release 2012; 161: 164-74.
    • (2012) J Control Release , vol.161 , pp. 164-174
    • Mahon, E.1    Salvati, A.2    Bombelli, F.B.3    Lynch, I.4    Dawson, K.A.5
  • 187
    • 55949130305 scopus 로고    scopus 로고
    • Diffusion in brain extracellular space
    • Sykova E, Nicholson C, Diffusion in brain extracellular space. Physiological Reviews 2008; 88: 1277-340.
    • (2008) Physiological Reviews , vol.88 , pp. 1277-1340
    • Sykova, E.1    Nicholson, C.2
  • 188
    • 84877292573 scopus 로고    scopus 로고
    • Diffusion of macromolecules in the Brain: Implications for drug delivery
    • Wolak DJ, Thorne RG, Diffusion of macromolecules in the Brain: implications for drug delivery. Molecular Pharmacology 2013; 10: 1492-504.
    • (2013) Molecular Pharmacology , vol.10 , pp. 1492-1504
    • Wolak, D.J.1    Thorne, R.G.2
  • 189
    • 84857651878 scopus 로고    scopus 로고
    • Nano erythropoietin is 10-times more effective than regular erythropoietin in neuroprotection in a neonatal rat model of hypoxia-ischemia
    • Chen H, Spagnoli F, Burris M, Rolland WB, Fajilan A, Dou H et al. Nano erythropoietin is 10-times more effective than regular erythropoietin in neuroprotection in a neonatal rat model of hypoxia-ischemia. Stroke 2012; 43: 884-7.
    • (2012) Stroke , vol.43 , pp. 884-887
    • Chen, H.1    Spagnoli, F.2    Burris, M.3    Rolland, W.B.4    Fajilan, A.5    Dou, H.6
  • 199
    • 36148980124 scopus 로고    scopus 로고
    • Drug delivery to the spinal cord tagged with nanowire enhances neuroprotective efficacy and functional recovery following trauma to the rat spinal cord
    • Sharma HS, Ali SF, Dong W, Tian ZR, Patnaik R, Patnaik S, et al. Drug delivery to the spinal cord tagged with nanowire enhances neuroprotective efficacy and functional recovery following trauma to the rat spinal cord. Ann N Y Acad Sci 2007; 1122: 197-218.
    • (2007) Ann N Y Acad Sci , vol.1122 , pp. 197-218
    • Sharma, H.S.1    Ali, S.F.2    Dong, W.3    Tian, Z.R.4    Patnaik, R.5    Patnaik, S.6
  • 200
    • 37048999111 scopus 로고    scopus 로고
    • A select combination of neurotrophins enhances neuroprotection and functional recovery following spinal cord injury
    • Sharma HS. A select combination of neurotrophins enhances neuroprotection and functional recovery following spinal cord injury. Ann N Y Acad Sci 2007; 1122, 95-111.
    • (2007) Ann N Y Acad Sci , vol.1122 , pp. 95-111
    • Sharma, H.S.1
  • 201
    • 34548301692 scopus 로고    scopus 로고
    • Brain edema and breakdown of the blood brain barrier during methamphetamine induced hyperthermia
    • Kiyatkin EA, Brown PL, Sharma HS. Brain edema and breakdown of the blood brain barrier during methamphetamine induced hyperthermia. Eur. J Neurosci 2007; 26:1242-53.
    • (2007) Eur. J Neurosci , vol.26 , pp. 1242-1253
    • Kiyatkin, E.A.1    Brown, P.L.2    Sharma, H.S.3
  • 202
    • 0033427851 scopus 로고    scopus 로고
    • Indirect evidence that drug brain targeting using polysorbate 80-coated polybutylcyanoacrylate nanoparticles is related to toxicity
    • Olivier JC, Fenart L, Chauvet R, Pariat C, Cecchelli R, Couet W. Indirect evidence that drug brain targeting using polysorbate 80-coated polybutylcyanoacrylate nanoparticles is related to toxicity. Pharm Res 1999; 16: 1836-42.
    • (1999) Pharm Res , vol.16 , pp. 1836-1842
    • Olivier, J.C.1    Fenart, L.2    Chauvet, R.3    Pariat, C.4    Cecchelli, R.5    Couet, W.6
  • 203
    • 34447628891 scopus 로고    scopus 로고
    • Nanoparticles aggravate heat stress induced cognitive deficits, blood brain barrier disruption, edema formation and brain pathology
    • Sharma HS, Sharma A. Nanoparticles aggravate heat stress induced cognitive deficits, blood brain barrier disruption, edema formation and brain pathology. Prog Brain Res 2007; 162: 245-73.
    • (2007) Prog Brain Res , vol.162 , pp. 245-273
    • Sharma, H.S.1    Sharma, A.2


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