Size and surface charge of gold nanoparticles determine absorption across intestinal barriers and accumulation in secondary target organs after oral administration

Nanotoxicology

Volumn 6, Issue 1, 2012, Pages 36-46

  Schleh, Carsten ^a   Semmler Behnke, Manuela ^a   Lipka, Jens ^a   Wenk, Alexander ^a   Hirn, Stephanie ^a   Schäffler, Martin ^a   Schmid, Günter ^b   Simon, Ulrich ^c   Kreyling, Wolfgang G ^a  

^a INSTITUTE OF EPIDEMIOLOGY   (Germany)

^b UNIVERSITY OF DUISBURG ESSEN   (Germany)

^c RWTH AACHEN UNIVERSITY   (Germany)

Author keywords

Absorption; Gastro intestinal tract; Gavage; Gold NP; in vivo biodistribution

Indexed keywords

GOLD NANOPARTICLE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BIOACCUMULATION; BRAIN; DRUG DELIVERY SYSTEM; DRUG INSTILLATION; FEMALE; HEART; INTESTINAL BARRIER; INTESTINE ABSORPTION; NONHUMAN; PARTICLE SIZE; PERMEABILITY BARRIER; PRIORITY JOURNAL; RAT; SURFACE CHARGE;

ADMINISTRATION, ORAL; ANIMALS; FEMALE; GASTROINTESTINAL CONTENTS; GASTROINTESTINAL TRACT; IMIDAZOLES; INTESTINAL ABSORPTION; LYSINE; METAL NANOPARTICLES; RATS; RATS, INBRED WKY; SURFACE PROPERTIES; TISSUE DISTRIBUTION;

RATTUS;

EID: 83955165727     PISSN: 17435390     EISSN: 17435404     Source Type: Journal    
DOI: 10.3109/17435390.2011.552811     Document Type: Article

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