A nanomedicine transports a peptide caspase-3 inhibitor across the blood-brain barrier and provides neuroprotection

Journal of Neuroscience

Volumn 29, Issue 44, 2009, Pages 13761-13769

  Karatas, Hulya ^a   Aktas, Yesim ^a,d   Gursoy Ozdemir, Yasemin ^a   Bodur, Ebru ^a   Yemisci, Muge ^a   Caban, Secil ^a   Vural, Atay ^a   Pinarbasli, Onur ^a   Capan, Yilmaz ^a   Fernandez Megia, Eduardo ^b   Novoa Carballal, Ramon ^b   Riguera, Ricardo ^b   Andrieux, Karine ^c   Couvreur, Patrick ^c   Dalkara, Turgay ^a  

^a HACETTEPE UNIVERSITY   (Turkey)

^b UNIVERSITY OF SANTIAGO DE COMPOSTELA   (Spain)

^c UNIVERSITÉ PARIS SACLAY   (France)

^d ATATÜRK UNIVERSITY   (Turkey)

Author keywords

[No Author keywords available]

Indexed keywords

BENZYLOXYCARBONYLASPARTYLGLUTAMYLVALYLASPARTYL FLUOROMETHYL KETONE; CASPASE 3 INHIBITOR; CHITOSAN; MACROGOL; MONOCLONAL ANTIBODY; NANOSPHERE; TRANSFERRIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD BRAIN BARRIER; BRAIN BLOOD VESSEL; BRAIN INFARCTION SIZE; CELL DEATH; CEREBELLUM; CONTROLLED STUDY; DRUG ACCUMULATION; DRUG PENETRATION; DRUG RELEASE; DRUG TARGETING; DRUG TRANSPORT; DRUG UPTAKE; ENZYME ACTIVITY; FLUORESCENCE MICROSCOPY; ISCHEMIA; LIVER; MIDDLE CEREBRAL ARTERY OCCLUSION; MOUSE; NANOMEDICINE; NEUROLOGIC DISEASE; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; REPERFUSION INJURY; SPLEEN;

EID: 70449441249     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.4246-09.2009     Document Type: Article

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