Comparison of the safety profiles of PLA50 and Me.PEG-PLA50 nanoparticles after single dose intravenous administration to rat

Colloids and Surfaces B: Biointerfaces

Volumn 16, Issue 1-4, 1999, Pages 173-183

  Plard, Jean Paul ^a   Bazile, Didier ^b  

^a SANOFI   (France)

^b Centre de Recherche   (France)

Author keywords

Coagulation; Intravenous toxicity; Nanoparticles; Poly(D,L lactic acid); Polyethylene glycol; Rat; Safety

Indexed keywords

DRUG CARRIER; MACROGOL; NANOPARTICLE; POLYLACTIC ACID;

ANIMAL EXPERIMENT; ARTICLE; DRUG DELIVERY SYSTEM; ENZYME ACTIVATION; INTRAVENOUS DRUG ADMINISTRATION; MALE; NONHUMAN; PARTIAL THROMBOPLASTIN TIME; PRIORITY JOURNAL; PROTHROMBIN TIME; RAT; RISK ASSESSMENT; THROMBOCYTOPENIA;

EID: 0032851387     PISSN: 09277765     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0927-7765(99)00068-5     Document Type: Article

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