Designing the nanoparticle-biomolecule interface for "targeting and therapeutic delivery"

Journal of Controlled Release

Volumn 161, Issue 2, 2012, Pages 164-174

  Mahon, Eugene ^a   Salvati, Anna ^a   Baldelli Bombelli, Francesca ^a,b   Lynch, Iseult ^a   Dawson, Kenneth A ^a  

^a UNIVERSITY COLLEGE DUBLIN   (Ireland)

^b UNIVERSITY OF EAST ANGLIA   (United Kingdom)

Author keywords

Bio nano interface; Engineered interface; Nanoparticle targeting; Receptor recognition

Indexed keywords

ACTIVE TARGETING; BIOLOGICAL FLUIDS; CELLULAR MACHINERY; ENDOGENOUS PROCESS; IN-SITU; IN-VIVO; INTEGRATION OF KNOWLEDGE; LIVING ORGANISMS; NANO-SCALE MATERIALS; NANOARCHITECTURES; NANOSCALE INTERACTIONS; PHYSIO-CHEMICAL; RECEPTOR RECOGNITION; SELECTIVE TRANSPORT; SPECIFIC SITES; SPECIFIC SURFACE; SUB-CELLULAR; SURFACE ADSORPTION; SURROUNDING ENVIRONMENT; THERAPEUTIC DELIVERY; TRANSPORT MECHANISM;

BIOLOGY; BIOMOLECULES; DIAGNOSIS; DISEASE CONTROL; DRUG THERAPY; GENE THERAPY; MACHINERY; NANOTECHNOLOGY;

NANOPARTICLES;

APOLIPOPROTEIN A1; APOLIPOPROTEIN E; EPIDERMAL GROWTH FACTOR RECEPTOR; FOLIC ACID; GOLD NANOPARTICLE; INSULIN; LIGAND; MOLECULAR SCAFFOLD; NANOCOATING; NANOPARTICLE; PACLITAXEL; POLYSACCHARIDE; SCAFFOLD PROTEIN; SILICON DIOXIDE; SMALL MOLECULE TRANSPORT AGENT;

BODY FLUID; CELL FUNCTION; CHEMICAL STRUCTURE; CONFORMATIONAL TRANSITION; DRUG ABSORPTION; DRUG CONJUGATION; DRUG DELIVERY SYSTEM; DRUG TARGETING; DRUG TRANSPORT; ENVIRONMENT; GENE THERAPY; HUMAN; KNOWLEDGE; MOLECULAR RECOGNITION; MOLECULE; NANOMEDICINE; NONHUMAN; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; REVIEW; SURFACE PROPERTY;

DRUG DELIVERY SYSTEMS; DRUG DESIGN; NANOPARTICLES; PROTEIN BINDING; SURFACE PROPERTIES;

EID: 84862646346     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2012.04.009     Document Type: Review

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