Efficacy of surface charge in targeting pegylated nanoparticles of sulpiride to the brain

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 74, Issue 3, 2010, Pages 442-450

  Parikh, Tapan ^a   Bommana, Murali Mohan ^a   Squillante III, Emilio ^a  

^a ST JOHN'S UNIVERSITY   (United States)

Author keywords

Adsorption; Albumin; Blood brain barrier; Cationized bovine serum albumin; CNS; Drug targeting; Microscopy; Nanoparticles; Pegylation; Sulpiride; Surface charge

Indexed keywords

BOVINE SERUM ALBUMIN; MACROGOL DERIVATIVE; MALEIMIDE; NANOPARTICLE; RHODAMINE B; SULPIRIDE;

ANIMAL EXPERIMENT; ARTICLE; DRUG ACCUMULATION; DRUG ACTIVITY; DRUG BLOOD LEVEL; DRUG BRAIN LEVEL; DRUG CLEARANCE; DRUG CONJUGATION; DRUG DELIVERY SYSTEM; DRUG DISTRIBUTION; DRUG EXCRETION; DRUG FORMULATION; DRUG RETENTION; DRUG UPTAKE; DRUG URINE LEVEL; EMULSION; FLUORESCENCE ANALYSIS; FLUORESCENCE MICROSCOPE; MALE; NONHUMAN; PARTICLE SIZE; POLYMERIZATION; RAT; SOLVENT EFFECT; SPRAGUE DAWLEY RAT; ZETA POTENTIAL;

ANIMALS; BRAIN; CATTLE; DRUG CARRIERS; DRUG COMPOUNDING; DRUG DELIVERY SYSTEMS; INJECTIONS, INTRAVENOUS; MALE; MALEIMIDES; MICROSCOPY, ELECTRON, SCANNING; NANOPARTICLES; PARTICLE SIZE; POLYESTERS; POLYETHYLENE GLYCOLS; RATS; RATS, SPRAGUE-DAWLEY; SERUM ALBUMIN, BOVINE; SULPIRIDE; SURFACE PROPERTIES; TISSUE DISTRIBUTION;

EID: 77649192717     PISSN: 09396411     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejpb.2009.11.001     Document Type: Article

References (32)

1. Smith M., and Gumbleton M. Endocytosis at the blood-brain barrier: from basic understanding to drug delivery strategies. J. Drug. Target. 14 (2006) 191-214
2. Lu W., Zhang Y., Tan Y., Hu K., Jiang X., and Fu S. Cationic albumin-conjugated pegylated nanoparticles as novel drug carrier for brain delivery. J. Control Release 107 (2005) 428-448
3. Kreuter J. Colloidal Drug Delivery Systems. first ed. (1994), Marcel Dekker, Inc.
4. Stolnik S., Illum L., and Davis S. Long-circulating microparticulate drug carriers. Adv. Drug. Deliver Rev. 16 (1995) 195-214
5. Lu W., Wan J., She Z., and Jiang X. Brain delivery property and accelerated blood clearance of cationic albumin conjugated pegylated NPs. J. Control Release 118 (2007) 38-53
6. Lu W., Tan Y., and Jiang X. Cationic albumin conjugated pegylated NPs with its transcytosis ability and little toxicity against blood-brain barrier. Int. J. Pharm. 295 (2005) 247-260
7. Muller N., and Dessing R. European Drug Index. fourth ed. (1997), CRC Press
8. Wiesel F., Alfredsson G., Ehrnebo M., and Sedvall G. The pharmacokinetics of Intravenous and oral sulpiride in healthy human subjects. Euro. J. Clin. Pharmaco. 17 (1995) 385-391
9. Olivier J., Huertas R., Calon F., and Pardridge W. Synthesis of pegylated immunonanoparticles. Pharm. Res. 19 (2002) 1137-1143
10. Wadhwani K., and Rapoport S. Enhanced permeabilities of cationized-bovine serum albumins at the blood-nerve and blood-brain barriers in awake rats. J. Neurosci. Res. 32 (2004) 407-414
11. Futami J., Maeda T., Kitazoe M., Nukui T., and Seno M. Preparation of potent cytotoxic ribonuclease by cationization: enhanced cellular uptake and decreased interaction with ribonuclease inhibitor by chemical modification of carboxyl groups. Biochemistry (2001) 7518-7524
12. Tarentino A. 2-Iminothiolane: a reagent for the introduction of sulfhydryl groups into oligosaccharides derived from asparagine-linked glycans. Glycobiology 3 (1993) 279-285
13. Triantafilou K., Triantafilou M., and Fernandez N. Lipopolysaccharide (LPS) labeled with Alexa 488 hydrazide as a novel probe for LPS binding studies. Cytometry 41 (2000) 316-320
14. Hoare D., and Koshland Jr. A method for the quantitative modification and estimation of carboxylic acid groups in proteins. J. Biol. Chem. 242 (1967) 2447-2453
15. Jin S., Ban E., Kim Y., and Kim C. Development of HPLC method for the determination of levosulpiride in human plasma. J. Pharm. Biomed. Anal. 35 (2004) 929-936
16. Hatziantoniou S., Nikas Y., and Deli G. Scanning electron microscopy study on nanoemulsions and solid lipid nanoparticles containing high amounts of ceramides. Micron 38 (2007) 819-823
17. W. Pardridge, P. Schimmel, Cationized Antibodies for Delivery through the Blood-Brain Barrier, US Patent 5004697, 1989.
18. Bulaj G., Kortemme T., and Goldenberg D. Quantitation of sulfhydryl DTNB, Ellman's reagent. Biochemistry 37 (1998) 8965-8972
19. Gill S., and Hippel P. Calculation of protein extinction coefficients from amino acid sequence data. Anal. Biochem. 182 (1989) 319-326
20. S. Rogers, Biological Application of Fluorescence Microscopy, Technical Report 99-006, 1999, pp. 3-18.
21. Chawla J., and Amiji M. Biodegradable poly(ε-Caprolactone) nanoparticles for targeted delivery of tamoxifen. Int. J. Pharm. 249 (2002) 127-138
22. M. Evening, Color Management, Adobe Photoshop CS for Photographers, 2004, pp. 354-407.
23. Dong Y., and Feng S. Methoxy poly(ethylene glycol)-poly(lactide) nanoparticles for controlled delivery of anticancer drugs. Biomaterials 25 (2004) 2843-2849
24. Zhang Y., Zha L., Wang C., and Jiang S. Preparation characterization and application of pyrene-loaded methoxy poly(ethylene glycol)-poly(lactic acid) copolymer nanoparticles. Colloid Polym. Sci. 282 (2004) 1323-1328
25. G. Friedli, Interaction of Deamidated Soluble Wheat Protein with Other Food Proteins and Metals. Unpublished Results, 1996.
26. Dean J. Lange's Handbook of Chemistry. 14th ed. (1999), Mc Graw-Hill
27. Govender T., Stolnik S., and Illum L. PLGA Nanoparticles prepared by nanoprecipitation: drug loading and release studies of a water soluble drug. J. Control Release 57 (1999) 171-185
28. Liu J., Cao W., and Sun X. Determination of sulpiride by capillary electrophoresis with end-Column electro generated chemiluminescence detection. Clin. Chem. 48 (2002) 1049-1058
29. N. Bhatt, R. Gheewala, Optimization of Physicochemical Factors Affecting Drug Loading of Sulpiride Loaded Nanoparticles, Unpublished Results, Saint Johns University, NY, 2008.
30. Guss R., Johnson F., and Maurice D. Rhodamine B as a test molecule in intraocular Dynamics. Invest. Ophthalmol. 25 (1984) 758-762
31. Horton R., Moran L., Ochs R., Rawn J., and Scrimgeour K. Lipids and Membranes. third ed. (2002), Prentice Hall (Prin. Biochem)
32. Jallouli Y., Paillard A., Chang J., Sevin E., and Betbeder D. Influence of surface charge and inner composition of porous nanoparticles to cross blood-brain barrier in vitro. Int. J. Pharm. 344 (2007) 103-109