메뉴 건너뛰기




Volumn 55, Issue 4, 2003, Pages 519-548

Poly(alkylcyanoacrylates) as biodegradable materials for biomedical applications

Author keywords

Degradation; Nanoparticles; Poly(alkylcyanoacrylates); Polymerization; Therapeutic applications

Indexed keywords

BIODEGRADATION; DRUG THERAPY; NANOSTRUCTURED MATERIALS; TOXICITY;

EID: 0037466349     PISSN: 0169409X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0169-409X(03)00041-3     Document Type: Review
Times cited : (516)

References (171)
  • 1
    • 0018387102 scopus 로고
    • Polycyanoacrylate nanocapsules as potential lysosomotropic carriers: Preparation, morphological and sorptive properties
    • Couvreur P., Kante B., Roland M., Guiot P., Bauduin P., Speiser P. Polycyanoacrylate nanocapsules as potential lysosomotropic carriers: preparation, morphological and sorptive properties. J. Pharm. Pharmacol. 31:1979;331-332.
    • (1979) J. Pharm. Pharmacol. , vol.31 , pp. 331-332
    • Couvreur, P.1    Kante, B.2    Roland, M.3    Guiot, P.4    Bauduin, P.5    Speiser, P.6
  • 3
    • 0012952576 scopus 로고
    • Adhesive composition
    • Bikales N. New York: Wiley-Interscience
    • Skeist I., Miron J. Adhesive composition. Bikales N. Encyclopedia of Polymer Science and Engineering. Suppl. Vol. 2:1977;1-19 Wiley-Interscience, New York.
    • (1977) Encyclopedia of Polymer Science and Engineering , vol.2 , Issue.SUPPL. , pp. 1-19
    • Skeist, I.1    Miron, J.2
  • 5
    • 0033211537 scopus 로고    scopus 로고
    • Tissue adhesives: A new method of wound repair
    • King M.E., Kinney A.Y. Tissue adhesives: a new method of wound repair. Nurse Pract. 24:1999;66-73.
    • (1999) Nurse Pract. , vol.24 , pp. 66-73
    • King, M.E.1    Kinney, A.Y.2
  • 8
    • 0034865113 scopus 로고    scopus 로고
    • The use of cyanoacrylate adhesives in peripheral embolization
    • Pollak J.S., White R.I. Jr. The use of cyanoacrylate adhesives in peripheral embolization. J. Vasc. Interv. Radiol. 12:2001;907-913.
    • (2001) J. Vasc. Interv. Radiol. , vol.12 , pp. 907-913
    • Pollak, J.S.1    White R.I., Jr.2
  • 10
    • 0034182386 scopus 로고    scopus 로고
    • Nano and microparticles as controlled drug delivery devices
    • Kumar N.M.V.R. Nano and microparticles as controlled drug delivery devices. J. Pharm. Pharm. Sci. 3:2000;234-258.
    • (2000) J. Pharm. Pharm. Sci. , vol.3 , pp. 234-258
    • Kumar, N.M.V.R.1
  • 13
    • 0001890054 scopus 로고    scopus 로고
    • Nanoparticles as drug delivery systems
    • J. Swarbrick, & J.C. Boylan. New York: Marcel Dekker
    • Fattal E., Vauthier C. Nanoparticles as drug delivery systems. Swarbrick J., Boylan J.C. Encyclopedia of Pharmaceutical Technology. 2002;1874-1892 Marcel Dekker, New York.
    • (2002) Encyclopedia of Pharmaceutical Technology , pp. 1874-1892
    • Fattal, E.1    Vauthier, C.2
  • 14
    • 0043222251 scopus 로고    scopus 로고
    • Degradation of poly(alkylcyanoacrylates)
    • J.P. Matsumara, A. Steinbuchel, Miscellaneous Biopolymers and Biodegradation of Synthetic Polymers, Wiley-VHC, New York, in press
    • Vauthier C., Couvreur P. Degradation of poly(alkylcyanoacrylates). Matsumara J.P., Steinbuchel A. Miscellaneous Biopolymers and Biodegradation of Synthetic Polymers. Handbook of Biopolymers. Vol. 9:2002;Wiley-VHC, New York. in press.
    • (2002) Handbook of Biopolymers , vol.9
    • Vauthier, C.1    Couvreur, P.2
  • 17
    • 0019957083 scopus 로고
    • Toxicity of polyalkylcyanoacrylate nanoparticles. II. Doxorubicin-loaded nanoparticles
    • Couvreur P., Kante B., Grislain L., Roland M., Speiser P. Toxicity of polyalkylcyanoacrylate nanoparticles. II. Doxorubicin-loaded nanoparticles. J. Pharm. Sci. 71:1982;790-792.
    • (1982) J. Pharm. Sci. , vol.71 , pp. 790-792
    • Couvreur, P.1    Kante, B.2    Grislain, L.3    Roland, M.4    Speiser, P.5
  • 23
    • 0034960612 scopus 로고    scopus 로고
    • Stealth polycyanoacrylate nanoparticles as tumor necrosis factor-α carriers: Pharmacokinetics and anti-tumor effects
    • Li Y.P., Pei Y.Y., Zhou Z.H., Zhang X.Y., Gu Z.H., Ding J., Zhou J.J., Gao X.J., Zhu J.H. Stealth polycyanoacrylate nanoparticles as tumor necrosis factor-α carriers: pharmacokinetics and anti-tumor effects. Biol. Pharm. Bull. 24:2001;662-665.
    • (2001) Biol. Pharm. Bull. , vol.24 , pp. 662-665
    • Li, Y.P.1    Pei, Y.Y.2    Zhou, Z.H.3    Zhang, X.Y.4    Gu, Z.H.5    Ding, J.6    Zhou, J.J.7    Gao, X.J.8    Zhu, J.H.9
  • 24
    • 0002868932 scopus 로고
    • Anionic and zwitterionic polymerization of α-cyanoacrylates
    • Pepper D.C. Anionic and zwitterionic polymerization of α-cyanoacrylates. J. Polym. Sci. Polym. Symp. 62:1978;65-77.
    • (1978) J. Polym. Sci. Polym. Symp. , vol.62 , pp. 65-77
    • Pepper, D.C.1
  • 25
    • 0030556084 scopus 로고    scopus 로고
    • Novel sub-ceiling temperature rapid depolymerization-repolymerization reactions of cyanoacrylate polymers
    • Ryan B., McCann G. Novel sub-ceiling temperature rapid depolymerization-repolymerization reactions of cyanoacrylate polymers. Macromol. Rapid Commun. 17:1996;217-227.
    • (1996) Macromol. Rapid Commun. , vol.17 , pp. 217-227
    • Ryan, B.1    McCann, G.2
  • 26
    • 0012900558 scopus 로고    scopus 로고
    • Expanded applications for octyl-2-cyanoacrylate as a tissue adhesive
    • Hollock G.G. Expanded applications for octyl-2-cyanoacrylate as a tissue adhesive. Ann. Plast. Surg. 47:2001;576.
    • (2001) Ann. Plast. Surg. , vol.47 , pp. 576
    • Hollock, G.G.1
  • 27
    • 0035319326 scopus 로고    scopus 로고
    • Comparison of 2-octyl cyanoacrylate adhesive, fibrin glue, and suturing for wound closure in the porcine urinary tract
    • Marcovich R., Williams A.L., Rubin M.A., Wolf J.S. Comparison of 2-octyl cyanoacrylate adhesive, fibrin glue, and suturing for wound closure in the porcine urinary tract. Urology. 57:2001;806-810.
    • (2001) Urology , vol.57 , pp. 806-810
    • Marcovich, R.1    Williams, A.L.2    Rubin, M.A.3    Wolf, J.S.4
  • 28
    • 0037062223 scopus 로고    scopus 로고
    • Tissue adhesive and postoperative allergic meningitis
    • Kitoh A., Arima Y., Nishigori C., Kikuta K., Miyachi Y. Tissue adhesive and postoperative allergic meningitis. Lancet. 359:2002;1669-1670.
    • (2002) Lancet , vol.359 , pp. 1669-1670
    • Kitoh, A.1    Arima, Y.2    Nishigori, C.3    Kikuta, K.4    Miyachi, Y.5
  • 29
    • 0032482248 scopus 로고    scopus 로고
    • Base-activated latent fingerprints fumed with a cyanoacrylate monomer. A quantitative study using Fourrier-transformed infra-red spectroscopy
    • Burns D.T., Brown J.K., Dinsmore A., Harvey K. Base-activated latent fingerprints fumed with a cyanoacrylate monomer. A quantitative study using Fourrier-transformed infra-red spectroscopy. Anal. Chim. Acta. 362:1998;171-176.
    • (1998) Anal. Chim. Acta , vol.362 , pp. 171-176
    • Burns, D.T.1    Brown, J.K.2    Dinsmore, A.3    Harvey, K.4
  • 30
    • 0036119629 scopus 로고    scopus 로고
    • Closure of lacerations and incision with octylcyanoacrylate: A multicenter randomized controlled trial
    • Singer A.J., Quinn J.V., Clark R.E., Hollander J.E. Closure of lacerations and incision with octylcyanoacrylate: a multicenter randomized controlled trial. Surgery. 131:2002;270-276.
    • (2002) Surgery , vol.131 , pp. 270-276
    • Singer, A.J.1    Quinn, J.V.2    Clark, R.E.3    Hollander, J.E.4
  • 31
    • 0036163423 scopus 로고    scopus 로고
    • Variceal bleeding and portal hypertension: Much to learn, much to explore
    • Bahsin D.K., Malhi N.J. Variceal bleeding and portal hypertension: much to learn, much to explore. Endoscopy. 34:2002;119-128.
    • (2002) Endoscopy , vol.34 , pp. 119-128
    • Bahsin, D.K.1    Malhi, N.J.2
  • 32
    • 0001908894 scopus 로고
    • Optimization of polycyanoacrylate nanoparticle preparation: Influence of sulfur dioxide and pH on nanoparticle characteristics
    • Lescure F., Zimmer C., Roy D., Couvreur P. Optimization of polycyanoacrylate nanoparticle preparation: influence of sulfur dioxide and pH on nanoparticle characteristics. J. Colloid Interface Sci. 154:1992;77-86.
    • (1992) J. Colloid Interface Sci. , vol.154 , pp. 77-86
    • Lescure, F.1    Zimmer, C.2    Roy, D.3    Couvreur, P.4
  • 33
    • 0021830705 scopus 로고
    • Particle size and size distribution of poly(butyl 2-cyanoacrylate) nanoparticles. II. Influence of stabilizers
    • Douglas S.J., Illum L., Davis S.S. Particle size and size distribution of poly(butyl 2-cyanoacrylate) nanoparticles. II. Influence of stabilizers. J. Colloid Interface Sci. 103:1985;154-163.
    • (1985) J. Colloid Interface Sci. , vol.103 , pp. 154-163
    • Douglas, S.J.1    Illum, L.2    Davis, S.S.3
  • 34
    • 0025222443 scopus 로고
    • Joint effect of monomer and stabilizer concentrations on the physico-chemical characteristics of poly(butyl-2-cyanoacrylate) nanoparticles
    • Alonso M.J., Sanchez A., Torres D., Seijo B., Vila-Jato J.L. Joint effect of monomer and stabilizer concentrations on the physico-chemical characteristics of poly(butyl-2-cyanoacrylate) nanoparticles. J. Microencapsul. 7:1990;517-526.
    • (1990) J. Microencapsul. , vol.7 , pp. 517-526
    • Alonso, M.J.1    Sanchez, A.2    Torres, D.3    Seijo, B.4    Vila-Jato, J.L.5
  • 35
    • 0025277126 scopus 로고
    • Design of nanoparticles of less than 50 nm diameter: Preparation, characterization and drug loading
    • Seijo B., Fattal E., Roblot-Treupel L., Couvreur P. Design of nanoparticles of less than 50 nm diameter: preparation, characterization and drug loading. Int. J. Pharm. 62:1990;1-7.
    • (1990) Int. J. Pharm. , vol.62 , pp. 1-7
    • Seijo, B.1    Fattal, E.2    Roblot-Treupel, L.3    Couvreur, P.4
  • 36
    • 0035821412 scopus 로고    scopus 로고
    • Combined hydroxypropyl-beta-cyclodextrin and poly(alkylcyanoacrylate) nanoparticles intended for oral administration of saquinavir
    • Boudad H., Legrand P., Lebas G., Cheron M., Duchêne D., Ponchel G.G. Combined hydroxypropyl-beta-cyclodextrin and poly(alkylcyanoacrylate) nanoparticles intended for oral administration of saquinavir. Int. J. Pharm. 218:2001;113-124.
    • (2001) Int. J. Pharm. , vol.218 , pp. 113-124
    • Boudad, H.1    Legrand, P.2    Lebas, G.3    Cheron, M.4    Duchêne, D.5    Ponchel, G.G.6
  • 40
    • 0025744048 scopus 로고
    • Biodegradable nanospheres containing phthalocyanines and naphthalocyanines for targeted photodynamic tumor therapy
    • Labib A., Lenaerts V., Chouinard F., Leroux J.C., Ouellet R., Van Lier J.E. Biodegradable nanospheres containing phthalocyanines and naphthalocyanines for targeted photodynamic tumor therapy. Pharm. Res. 8:1991;1027-1031.
    • (1991) Pharm. Res. , vol.8 , pp. 1027-1031
    • Labib, A.1    Lenaerts, V.2    Chouinard, F.3    Leroux, J.C.4    Ouellet, R.5    Van Lier, J.E.6
  • 42
    • 0022630942 scopus 로고
    • Poly(butyl-2-cyanoacrylate) nanoparticles with differing surface charges
    • Douglas S.J., Illum L., Davis S.S. Poly(butyl-2-cyanoacrylate) nanoparticles with differing surface charges. J. Control. Release. 3:1986;15-23.
    • (1986) J. Control. Release , vol.3 , pp. 15-23
    • Douglas, S.J.1    Illum, L.2    Davis, S.S.3
  • 43
    • 0031553828 scopus 로고    scopus 로고
    • Development of sterically stabilized poly(isobutyl 2-cyanoacrylate) nanoparticles by chemical coupling of poly(ethylene glycol)
    • Peracchia M.T., Vauthier C., Puisieux F., Couvreur P. Development of sterically stabilized poly(isobutyl 2-cyanoacrylate) nanoparticles by chemical coupling of poly(ethylene glycol). J. Biomed. Mater. Res. 34:1997;317-326.
    • (1997) J. Biomed. Mater. Res. , vol.34 , pp. 317-326
    • Peracchia, M.T.1    Vauthier, C.2    Puisieux, F.3    Couvreur, P.4
  • 44
    • 0031544343 scopus 로고    scopus 로고
    • Investigation of the formation of sterically stabilized poly(ethylene glycol/isobutylcyanoacrylate) nanoparticles by chemical grafting of polyethylene glycol during the polymerization of isobutyl cyanoacrylate
    • Peracchia M.T., Vauthier C., Popa M.I., Puisieux F., Couvreur P. Investigation of the formation of sterically stabilized poly(ethylene glycol/isobutylcyanoacrylate) nanoparticles by chemical grafting of polyethylene glycol during the polymerization of isobutyl cyanoacrylate. S.T.P. Pharma Sci. 7:1997;513-520.
    • (1997) S.T.P. Pharma Sci. , vol.7 , pp. 513-520
    • Peracchia, M.T.1    Vauthier, C.2    Popa, M.I.3    Puisieux, F.4    Couvreur, P.5
  • 45
    • 0034096471 scopus 로고    scopus 로고
    • Formation of positively charged poly(butyl cyanoacrylate) nanoparticles stabilized by chitosan
    • Yang S.C., Ge H.X., Hu Y., Jiang X.Q., Yang C.Z. Formation of positively charged poly(butyl cyanoacrylate) nanoparticles stabilized by chitosan. Coll. Polym. Sci. 278:2000;285-292.
    • (2000) Coll. Polym. Sci. , vol.278 , pp. 285-292
    • Yang, S.C.1    Ge, H.X.2    Hu, Y.3    Jiang, X.Q.4    Yang, C.Z.5
  • 47
    • 0022607044 scopus 로고
    • Nanoparticles from microemulsions
    • Gasco M., Trotta M. Nanoparticles from microemulsions. Int. J. Pharm. 29:1986;267-268.
    • (1986) Int. J. Pharm. , vol.29 , pp. 267-268
    • Gasco, M.1    Trotta, M.2
  • 48
    • 0029833171 scopus 로고    scopus 로고
    • A new nanocapsule formulation with hydrophilic core: Application to the oral administration of salmon calcitonin in rats
    • Vranckx H., Demoustier M., Deleers M. A new nanocapsule formulation with hydrophilic core: application to the oral administration of salmon calcitonin in rats. Eur. J. Pharm. Biopharm. 42:1996;345-347.
    • (1996) Eur. J. Pharm. Biopharm. , vol.42 , pp. 345-347
    • Vranckx, H.1    Demoustier, M.2    Deleers, M.3
  • 49
    • 0033840158 scopus 로고    scopus 로고
    • Polyisobutylcyanoacrylate nanocapsules containing an aqueous core as a novel colloidal carrier for the delivery of oligonucleotides
    • Lambert G., Fattal E., Pinto-Alphandary H., Gulik A., Couvreur P. Polyisobutylcyanoacrylate nanocapsules containing an aqueous core as a novel colloidal carrier for the delivery of oligonucleotides. Pharm. Res. 17:2000;707-714.
    • (2000) Pharm. Res. , vol.17 , pp. 707-714
    • Lambert, G.1    Fattal, E.2    Pinto-Alphandary, H.3    Gulik, A.4    Couvreur, P.5
  • 50
    • 0033849510 scopus 로고    scopus 로고
    • Preparation of biodegradable insulin nanocapsules from biocompatible microemulsions
    • Watnasirichaikul S., Davies N.M., Rades R., Tucker I.G. Preparation of biodegradable insulin nanocapsules from biocompatible microemulsions. Pharm. Res. 17:2000;684-689.
    • (2000) Pharm. Res. , vol.17 , pp. 684-689
    • Watnasirichaikul, S.1    Davies, N.M.2    Rades, R.3    Tucker, I.G.4
  • 52
    • 0031573490 scopus 로고    scopus 로고
    • Study of the mechanism of insulin encapsulation in poly(isobutylcyanoacrylate) nanocapsules obtained by interfacial polymerization
    • Aboubakar M., Puisieux F., Couvreur P., Deyme M., Vauthier C. Study of the mechanism of insulin encapsulation in poly(isobutylcyanoacrylate) nanocapsules obtained by interfacial polymerization. J. Biomed. Mater. Res. 47:1999;568-576.
    • (1999) J. Biomed. Mater. Res. , vol.47 , pp. 568-576
    • Aboubakar, M.1    Puisieux, F.2    Couvreur, P.3    Deyme, M.4    Vauthier, C.5
  • 53
    • 0342656493 scopus 로고    scopus 로고
    • Improved preparation and physical studies of polybutylcyanoacrylate nanocapsules
    • Wohlgemuth M., Mächtle W., Mayer C. Improved preparation and physical studies of polybutylcyanoacrylate nanocapsules. J. Microencapsul. 17:2000;437-448.
    • (2000) J. Microencapsul. , vol.17 , pp. 437-448
    • Wohlgemuth, M.1    Mächtle, W.2    Mayer, C.3
  • 54
    • 0028791550 scopus 로고
    • Influence of the preparation conditions in poly(ethylcyanoacrylate) nanocapsules formation
    • Puglisi G., Fresta M., Giammona G., Venture C.A. Influence of the preparation conditions in poly(ethylcyanoacrylate) nanocapsules formation. Int. J. Pharm. 125:1995;283-287.
    • (1995) Int. J. Pharm. , vol.125 , pp. 283-287
    • Puglisi, G.1    Fresta, M.2    Giammona, G.3    Venture, C.A.4
  • 55
    • 0030131010 scopus 로고    scopus 로고
    • Preparation and characterization of polyethyl-2-cyanoacrylate nanocapsules containing antiepileptic drugs
    • Fresta M., Cavallaro G., Giammona G., Wehrli E., Puglisi G. Preparation and characterization of polyethyl-2-cyanoacrylate nanocapsules containing antiepileptic drugs. Biomaterials. 17:1996;751-758.
    • (1996) Biomaterials , vol.17 , pp. 751-758
    • Fresta, M.1    Cavallaro, G.2    Giammona, G.3    Wehrli, E.4    Puglisi, G.5
  • 56
    • 0023856501 scopus 로고
    • New approach for oral administration of insulin with polyalkylcyanoacrylate nanocapsules as drug carrier
    • Damge C., Michel C., Aprahamian M., Couvreur P. New approach for oral administration of insulin with polyalkylcyanoacrylate nanocapsules as drug carrier. Diabetes. 37:1988;246-251.
    • (1988) Diabetes , vol.37 , pp. 246-251
    • Damge, C.1    Michel, C.2    Aprahamian, M.3    Couvreur, P.4
  • 57
    • 0026074310 scopus 로고
    • The effect of site of administration in the gastrointestinal tract on the absorption of insulin from nanocapsules in diabetic rats
    • Michel C., Aprahamian M., Defontaine L., Couvreur P., Damge C. The effect of site of administration in the gastrointestinal tract on the absorption of insulin from nanocapsules in diabetic rats. J. Pharm. Pharmacol. 43:1990;1-5.
    • (1990) J. Pharm. Pharmacol. , vol.43 , pp. 1-5
    • Michel, C.1    Aprahamian, M.2    Defontaine, L.3    Couvreur, P.4    Damge, C.5
  • 58
    • 0028283741 scopus 로고
    • Calcitonin and insulin in isobutylcyanoacrylate nanocapsules: Protection against proteases and effect on intestinal absorption in rats
    • Lowe P.J., Temple C.S. Calcitonin and insulin in isobutylcyanoacrylate nanocapsules: protection against proteases and effect on intestinal absorption in rats. J. Pharm. Pharmacol. 46:1994;547-552.
    • (1994) J. Pharm. Pharmacol. , vol.46 , pp. 547-552
    • Lowe, P.J.1    Temple, C.S.2
  • 59
    • 0001537043 scopus 로고
    • Block copolymer nanoparticles of ethylene oxide and isobutyl cyanoacrylate
    • Choi Y.K., Kim Y.H., Kim S.W. Block copolymer nanoparticles of ethylene oxide and isobutyl cyanoacrylate. Macromolecules. 28:1995;8419-8421.
    • (1995) Macromolecules , vol.28 , pp. 8419-8421
    • Choi, Y.K.1    Kim, Y.H.2    Kim, S.W.3
  • 60
    • 0031075105 scopus 로고    scopus 로고
    • Synthesis of a novel poly(MePEG cyanoacrylate-co-alkylcyanoacrylate) amphiphilic copolymer for nanoparticle technology
    • Peracchia M.T., Desmaële D., Couvreur P., D'Angelo J. Synthesis of a novel poly(MePEG cyanoacrylate-co-alkylcyanoacrylate) amphiphilic copolymer for nanoparticle technology. Macromolecules. 30:1997;846-851.
    • (1997) Macromolecules , vol.30 , pp. 846-851
    • Peracchia, M.T.1    Desmaële, D.2    Couvreur, P.3    D'Angelo, J.4
  • 61
    • 0013230147 scopus 로고    scopus 로고
    • Development of novel technologies for the synthesis of biodegradable pegylated nanoparticles
    • G. Gregoriadis, B. McCormack, Strategies for Stealth Therapeutic Systems, Plenum Press, New York
    • Peracchia M.T., Desmaële D., Vauthier C., Labarre D., Fattal E., D'Angelo J., Couvreur P. Development of novel technologies for the synthesis of biodegradable pegylated nanoparticles. Gregoriadis G., McCormack B. Strategies for Stealth Therapeutic Systems. Targeting of Drugs. Vol. 6:1998;225-239 Plenum Press, New York.
    • (1998) Targeting of Drugs , vol.6 , pp. 225-239
    • Peracchia, M.T.1    Desmaële, D.2    Vauthier, C.3    Labarre, D.4    Fattal, E.5    D'Angelo, J.6    Couvreur, P.7
  • 62
    • 0031954707 scopus 로고    scopus 로고
    • Pegylated nanoparticles from a novel methoxypolyethylene glycol cyanoacrylate-hexadecyl cyanoacrylate amphiphilic copolymer
    • Peracchia M.T., Vauthier C., Desmaële D., Gulik A., Dedieu J.C., Demoy M., D'Angelo J., Couvreur P. Pegylated nanoparticles from a novel methoxypolyethylene glycol cyanoacrylate-hexadecyl cyanoacrylate amphiphilic copolymer. Pharm. Res. 15:1998;548-554.
    • (1998) Pharm. Res. , vol.15 , pp. 548-554
    • Peracchia, M.T.1    Vauthier, C.2    Desmaële, D.3    Gulik, A.4    Dedieu, J.C.5    Demoy, M.6    D'Angelo, J.7    Couvreur, P.8
  • 68
    • 0028145461 scopus 로고
    • Characterization of polybutylcyanoacrylate nanoparticles: Quantification of PBCA polymer and dextran
    • Langer K., Seegmüller E., Zimmer A., Kreuter J. Characterization of polybutylcyanoacrylate nanoparticles: quantification of PBCA polymer and dextran. Int. J. Pharm. 110:1994;21-27.
    • (1994) Int. J. Pharm. , vol.110 , pp. 21-27
    • Langer, K.1    Seegmüller, E.2    Zimmer, A.3    Kreuter, J.4
  • 69
    • 0025124073 scopus 로고
    • In vitro model for the degradation of alkylcyanoacrylate nanoparticles
    • Müller R.H., Lherm C., Herbort J., Couvreur P. In vitro model for the degradation of alkylcyanoacrylate nanoparticles. Biomaterials. 11:1990;590-595.
    • (1990) Biomaterials , vol.11 , pp. 590-595
    • Müller, R.H.1    Lherm, C.2    Herbort, J.3    Couvreur, P.4
  • 70
    • 0028127992 scopus 로고
    • Influence of enzymes on the stability of polybutylcyanoacrylate nanoparticles
    • Scherer D., Robinson J.R., Kreuter J. Influence of enzymes on the stability of polybutylcyanoacrylate nanoparticles. Int. J. Pharm. 101:1994;165-168.
    • (1994) Int. J. Pharm. , vol.101 , pp. 165-168
    • Scherer, D.1    Robinson, J.R.2    Kreuter, J.3
  • 71
    • 0026653682 scopus 로고
    • II. Cytotoxicity of cyanoacrylate nanoparticles with different alkyl chain length
    • Lherm C., Muller R., Puisieux F., Couvreur P. II. Cytotoxicity of cyanoacrylate nanoparticles with different alkyl chain length. Int. J. Pharm. 84:1992;13-22.
    • (1992) Int. J. Pharm. , vol.84 , pp. 13-22
    • Lherm, C.1    Muller, R.2    Puisieux, F.3    Couvreur, P.4
  • 72
    • 0015338378 scopus 로고
    • Degradation of poly(methylcyanoacrylates)
    • Wade C.W., Leonard F. Degradation of poly(methylcyanoacrylates). J. Biomed. Mater. Res. 6:1972;215-220.
    • (1972) J. Biomed. Mater. Res. , vol.6 , pp. 215-220
    • Wade, C.W.1    Leonard, F.2
  • 73
    • 0018991673 scopus 로고
    • In vitro heterogenous degradation of poly(n-alkyl α-cyanoacrylates)
    • Vezin W.R., Florence A.T. In vitro heterogenous degradation of poly(n-alkyl α-cyanoacrylates). J. Biomed. Mater. Res. 14:1980;93-106.
    • (1980) J. Biomed. Mater. Res. , vol.14 , pp. 93-106
    • Vezin, W.R.1    Florence, A.T.2
  • 74
    • 0023855375 scopus 로고
    • Effects of isobutyl-2-cyanoacrylate polymer on cultured cells derived from murine cerebral microvessels
    • Vinters H.V., Ho H.W. Effects of isobutyl-2-cyanoacrylate polymer on cultured cells derived from murine cerebral microvessels. Toxicol. In Vitro. 2:1988;37-41.
    • (1988) Toxicol. In Vitro , vol.2 , pp. 37-41
    • Vinters, H.V.1    Ho, H.W.2
  • 75
    • 0025341818 scopus 로고
    • Modification of the synthesis and investigation of properties for 2-cyanoacrylates
    • Tseng Y.C., Hyon S.H., Ikada Y. Modification of the synthesis and investigation of properties for 2-cyanoacrylates. Biomaterials. 11:1990;73-79.
    • (1990) Biomaterials , vol.11 , pp. 73-79
    • Tseng, Y.C.1    Hyon, S.H.2    Ikada, Y.3
  • 77
    • 0002642023 scopus 로고
    • Etude du mécanisme de dégradation des nanoparticules de polycyanoacrylate d'alkyle
    • Ley D., Couvreur P., Lenaerts V., Roland M., Speiser P. Etude du mécanisme de dégradation des nanoparticules de polycyanoacrylate d'alkyle. Labo Pharma-Probl. Tech. 32:1984;100-104.
    • (1984) Labo Pharma-Probl. Tech. , vol.32 , pp. 100-104
    • Ley, D.1    Couvreur, P.2    Lenaerts, V.3    Roland, M.4    Speiser, P.5
  • 79
  • 82
    • 0026536219 scopus 로고
    • Polyalkylcyanoacrylate nanoparticles as polymeric carriers for antisense oligonucleotides
    • Chavany C., Ledoan T., Couvreur P., Puisieux F., Helene C. Polyalkylcyanoacrylate nanoparticles as polymeric carriers for antisense oligonucleotides. Pharm. Res. 9:1992;441-449.
    • (1992) Pharm. Res. , vol.9 , pp. 441-449
    • Chavany, C.1    Ledoan, T.2    Couvreur, P.3    Puisieux, F.4    Helene, C.5
  • 86
    • 0025312405 scopus 로고
    • Hepatic tissue distribution of doxorubicin-loaded nanoparticles after i.v. administration in reticulosarcoma M 5076 metastasis-bearing mice
    • Chiannilkulchai N., Ammoury N., Caillou B., Devissaguet J.P., Couvreur P. Hepatic tissue distribution of doxorubicin-loaded nanoparticles after i.v. administration in reticulosarcoma M 5076 metastasis-bearing mice. Cancer Chemother. Pharmacol. 26:1990;122-126.
    • (1990) Cancer Chemother. Pharmacol. , vol.26 , pp. 122-126
    • Chiannilkulchai, N.1    Ammoury, N.2    Caillou, B.3    Devissaguet, J.P.4    Couvreur, P.5
  • 89
    • 0024950991 scopus 로고
    • Physicochemical characterization of polymeric nanocapsules and in vitro release of indomethacin as a drug model
    • Ammoury N., Fessi H., Devissaguet J.P., Puisieux F., Benita S. Physicochemical characterization of polymeric nanocapsules and in vitro release of indomethacin as a drug model. S.T.P. Pharma. 5:1989;642-646.
    • (1989) S.T.P. Pharma , vol.5 , pp. 642-646
    • Ammoury, N.1    Fessi, H.2    Devissaguet, J.P.3    Puisieux, F.4    Benita, S.5
  • 90
    • 0024448619 scopus 로고
    • Toxicité des nanoparticles à base de polycyanoacrylates d'alkyle
    • Couvreur P., Vranckx H., Brasseur F., Roland M. Toxicité des nanoparticles à base de polycyanoacrylates d'alkyle. S.T.P. Pharma Sci. 5:1989;31-37.
    • (1989) S.T.P. Pharma Sci. , vol.5 , pp. 31-37
    • Couvreur, P.1    Vranckx, H.2    Brasseur, F.3    Roland, M.4
  • 91
    • 0027474788 scopus 로고
    • Cell cultures for the assessment of toxicity and uptake of polymeric drug carriers
    • Maassen S., Fattal E., Muller R., Couvreur P. Cell cultures for the assessment of toxicity and uptake of polymeric drug carriers. S.T.P. Pharma Sci. 3:1993;11-22.
    • (1993) S.T.P. Pharma Sci. , vol.3 , pp. 11-22
    • Maassen, S.1    Fattal, E.2    Muller, R.3    Couvreur, P.4
  • 94
    • 0024457952 scopus 로고
    • Increased cytotoxicity of nanoparticle-carried adriamycin in vitro and potentiation by verapamil and amiodarone
    • Kubiak C., Couvreur P., Manil L., Clausse B. Increased cytotoxicity of nanoparticle-carried adriamycin in vitro and potentiation by verapamil and amiodarone. Biomaterials. 10:1989;553-556.
    • (1989) Biomaterials , vol.10 , pp. 553-556
    • Kubiak, C.1    Couvreur, P.2    Manil, L.3    Clausse, B.4
  • 95
    • 0002448548 scopus 로고
    • The effects of poly(alkylcynoacrylate) nanoparticles on human normal and malignant mesenchymal cells in vitro
    • Gipps E., Groscurt P., Kreuter J., Speiser P.P. The effects of poly(alkylcynoacrylate) nanoparticles on human normal and malignant mesenchymal cells in vitro. Int. J. Pharm. 40:1987;23-31.
    • (1987) Int. J. Pharm. , vol.40 , pp. 23-31
    • Gipps, E.1    Groscurt, P.2    Kreuter, J.3    Speiser, P.P.4
  • 96
    • 0026717840 scopus 로고
    • Macrophage activation by polymeric nanoparticles of polyalkylcyanoacrylates: Activity against intracellular Leishmania donovani associated with hydrogen peroxide production
    • Gaspar R., Preat V., Opperdoes F.R., Roland M. Macrophage activation by polymeric nanoparticles of polyalkylcyanoacrylates: activity against intracellular Leishmania donovani associated with hydrogen peroxide production. Pharm. Res. 9:1992;782-787.
    • (1992) Pharm. Res. , vol.9 , pp. 782-787
    • Gaspar, R.1    Preat, V.2    Opperdoes, F.R.3    Roland, M.4
  • 98
    • 0031105909 scopus 로고    scopus 로고
    • Evaluation of hepatic antioxidant systems after intravenous administration of polymeric nanoparticles
    • Fernandez-Urrusuno R., Fattal E., Féger J., Couvreur P., Théron P. Evaluation of hepatic antioxidant systems after intravenous administration of polymeric nanoparticles. Biomaterials. 18:1997;511-517.
    • (1997) Biomaterials , vol.18 , pp. 511-517
    • Fernandez-Urrusuno, R.1    Fattal, E.2    Féger, J.3    Couvreur, P.4    Théron, P.5
  • 101
    • 0024420455 scopus 로고
    • Treatment of experimental salmonellosis in mice with ampicillin-bound nanoparticles
    • Fattal E., Youssef M., Couvreur P., Andremont A. Treatment of experimental salmonellosis in mice with ampicillin-bound nanoparticles. Antimicrob. Agents Chemother. 33:1989;1540-1543.
    • (1989) Antimicrob. Agents Chemother. , vol.33 , pp. 1540-1543
    • Fattal, E.1    Youssef, M.2    Couvreur, P.3    Andremont, A.4
  • 103
    • 0026666177 scopus 로고
    • Effect of nanoparticle-bound ampicillin on the survival of Listeria monocytogenes in mouse peritoneal macrophages
    • Forestier F., Gerrier P., Chaumard C., Quero A.M., Couvreur P., Labarre C. Effect of nanoparticle-bound ampicillin on the survival of Listeria monocytogenes in mouse peritoneal macrophages. J. Antimicrob. Chemother. 30:1992;173-179.
    • (1992) J. Antimicrob. Chemother. , vol.30 , pp. 173-179
    • Forestier, F.1    Gerrier, P.2    Chaumard, C.3    Quero, A.M.4    Couvreur, P.5    Labarre, C.6
  • 104
    • 0028204890 scopus 로고
    • The uptake of ampicillin-loaded nanoparticles by murine macrophages infected with Salmonella typhimurium
    • Balland O., Pinto-Alphandary H., Pecquet S., Andremont A., Couvreur P. The uptake of ampicillin-loaded nanoparticles by murine macrophages infected with Salmonella typhimurium. J. Antimicrob. Chemother. 33:1994;509-522.
    • (1994) J. Antimicrob. Chemother. , vol.33 , pp. 509-522
    • Balland, O.1    Pinto-Alphandary, H.2    Pecquet, S.3    Andremont, A.4    Couvreur, P.5
  • 105
    • 0028009676 scopus 로고
    • Intracellular visualization of ampicillin-loaded nanoparticles in peritoneal macrophages infected in vitro with Salmonella typhimurium
    • Pinto-Alphandary H., Balland O., Laurent M., Andremont A., Puisieux F., Couvreur P. Intracellular visualization of ampicillin-loaded nanoparticles in peritoneal macrophages infected in vitro with Salmonella typhimurium. Pharm. Res. 11:1994;38-46.
    • (1994) Pharm. Res. , vol.11 , pp. 38-46
    • Pinto-Alphandary, H.1    Balland, O.2    Laurent, M.3    Andremont, A.4    Puisieux, F.5    Couvreur, P.6
  • 106
    • 0025830323 scopus 로고
    • Inhibition of macrophage phagosome-lysosome fusion by Salmonella typhimurium
    • Buchmeier N.A., Heffron F. Inhibition of macrophage phagosome-lysosome fusion by Salmonella typhimurium. Infect. Immun. 59:1991;2232-2238.
    • (1991) Infect. Immun. , vol.59 , pp. 2232-2238
    • Buchmeier, N.A.1    Heffron, F.2
  • 107
    • 0031947364 scopus 로고    scopus 로고
    • Drug targeting by polyalkylcyanoacrylate nanoparticles is not efficient against persistent Salmonella
    • Page-Clisson M.E., Pinto-Alphandary H., Chachaty E., Couvreur P., Andremont A. Drug targeting by polyalkylcyanoacrylate nanoparticles is not efficient against persistent Salmonella. Pharm. Res. 15:1998;544-549.
    • (1998) Pharm. Res. , vol.15 , pp. 544-549
    • Page-Clisson, M.E.1    Pinto-Alphandary, H.2    Chachaty, E.3    Couvreur, P.4    Andremont, A.5
  • 108
    • 0026507069 scopus 로고
    • Drug targeting with polyalkylcyanoacrylate nanoparticles - In vitro activity of primaquine-loaded nanoparticles against intracellular Leishmania donovani
    • Gaspar R., Opperdoes F.R., Preat V., Roland M. Drug targeting with polyalkylcyanoacrylate nanoparticles - in vitro activity of primaquine-loaded nanoparticles against intracellular Leishmania donovani. Ann. Trop. Med. Parasitol. 86:1992;782-787.
    • (1992) Ann. Trop. Med. Parasitol. , vol.86 , pp. 782-787
    • Gaspar, R.1    Opperdoes, F.R.2    Preat, V.3    Roland, M.4
  • 109
    • 0024573406 scopus 로고
    • Development of dehydroemetine nanoparticles for the treatment of visceral leishmaniasis
    • Fouarge M., Dewulf M., Couvreur P., Roland M., Vranckx H. Development of dehydroemetine nanoparticles for the treatment of visceral leishmaniasis. J. Microencapsul. 6:1989;29-34.
    • (1989) J. Microencapsul. , vol.6 , pp. 29-34
    • Fouarge, M.1    Dewulf, M.2    Couvreur, P.3    Roland, M.4    Vranckx, H.5
  • 112
    • 0029041515 scopus 로고
    • Liposomal doxorubicin-induced toxicity: Depletion and impairment of phagocytic activity of liver macrophages
    • Daemen T., Hofstede G., Ten Kate M.T., Bakker-Woudenberg I.A., Scherphof G.L. Liposomal doxorubicin-induced toxicity: depletion and impairment of phagocytic activity of liver macrophages. Int. J. Cancer. 61:1995;716-721.
    • (1995) Int. J. Cancer , vol.61 , pp. 716-721
    • Daemen, T.1    Hofstede, G.2    Ten Kate, M.T.3    Bakker-Woudenberg, I.A.4    Scherphof, G.L.5
  • 114
    • 0021852930 scopus 로고
    • Detection of P-glycoprotein in multidrug-resistant cell lines by monoclonal antibodies
    • Kartner N., Evernden-Porelle D., Bradley G., Ling V. Detection of P-glycoprotein in multidrug-resistant cell lines by monoclonal antibodies. Nature. 316:1985;820-823.
    • (1985) Nature , vol.316 , pp. 820-823
    • Kartner, N.1    Evernden-Porelle, D.2    Bradley, G.3    Ling, V.4
  • 115
    • 0025871344 scopus 로고
    • Vectorisation of doxorubicin in nanospheres and reversion of pleiotropic resistance of tumor cells
    • Treupel L., Poupon M.F., Couvreur P., Puisieux F. Vectorisation of doxorubicin in nanospheres and reversion of pleiotropic resistance of tumor cells. C.R. Acad. Sci. III. 313:1991;171-174.
    • (1991) C.R. Acad. Sci. III , vol.313 , pp. 171-174
    • Treupel, L.1    Poupon, M.F.2    Couvreur, P.3    Puisieux, F.4
  • 117
    • 0028036158 scopus 로고
    • Enhanced cytotoxicity of doxorubicin encapsulated in polyisohexylcyanoacrylate nanospheres against multidrug-resistant tumour cells in culture
    • Bennis S., Chapey C., Couvreur P., Robert J. Enhanced cytotoxicity of doxorubicin encapsulated in polyisohexylcyanoacrylate nanospheres against multidrug-resistant tumour cells in culture. Eur. J. Cancer. 1:1994;89-93.
    • (1994) Eur. J. Cancer , vol.1 , pp. 89-93
    • Bennis, S.1    Chapey, C.2    Couvreur, P.3    Robert, J.4
  • 118
    • 0028107382 scopus 로고
    • Some parameters influencing cytotoxicity of free doxorubicin loaded nanoparticles in sensitive and multidrug resistant leucemic murine cells: Incubation time, number of particles per cell
    • Nemati F., Dubernet C., Colin de Verdière A., Poupon M.F., Treupel Acar L., Puisieux F., Couvreur P. Some parameters influencing cytotoxicity of free doxorubicin loaded nanoparticles in sensitive and multidrug resistant leucemic murine cells: incubation time, number of particles per cell. Int. J. Pharm. 102:1994;55-62.
    • (1994) Int. J. Pharm. , vol.102 , pp. 55-62
    • Nemati, F.1    Dubernet, C.2    Colin de Verdière, A.3    Poupon, M.F.4    Treupel Acar, L.5    Puisieux, F.6    Couvreur, P.7
  • 122
    • 0032734851 scopus 로고    scopus 로고
    • Ability of doxorubicin-loaded nanoparticles to overcome multidrug resistance of tumor cells after their capture by macrophages
    • Soma C.E., Dubernet C., Barratt G., Nemati F., Appel M., Benita S., Couvreur P. Ability of doxorubicin-loaded nanoparticles to overcome multidrug resistance of tumor cells after their capture by macrophages. Pharm. Res. 16:1999;1710-1716.
    • (1999) Pharm. Res. , vol.16 , pp. 1710-1716
    • Soma, C.E.1    Dubernet, C.2    Barratt, G.3    Nemati, F.4    Appel, M.5    Benita, S.6    Couvreur, P.7
  • 123
    • 0034632936 scopus 로고    scopus 로고
    • Investigation of the role of macrophages on the cytotoxicity of doxorubicin and doxorubicin-loaded nanoparticles on M5076 cells in vitro
    • Soma C.E., Dubernet C., Barratt G., Benita S., Couvreur P. Investigation of the role of macrophages on the cytotoxicity of doxorubicin and doxorubicin-loaded nanoparticles on M5076 cells in vitro. J. Control. Release. 68:2000;283-289.
    • (2000) J. Control. Release , vol.68 , pp. 283-289
    • Soma, C.E.1    Dubernet, C.2    Barratt, G.3    Benita, S.4    Couvreur, P.5
  • 124
    • 0032881090 scopus 로고    scopus 로고
    • Antisense oligonucleotide delivery with polyhexylcyanoacrylate nanoparticles as carriers
    • Zimmer A. Antisense oligonucleotide delivery with polyhexylcyanoacrylate nanoparticles as carriers. Methods: A Companion to Methods in Enzymology. 18:1999;286-295.
    • (1999) Methods: A Companion to Methods in Enzymology , vol.18 , pp. 286-295
    • Zimmer, A.1
  • 125
    • 0027935614 scopus 로고
    • Adsorption of oligonucleotides onto polyisohexylcyanoacrylate nanoparticles protects them against nucleases and increases their cellular uptake
    • Chavany C., Saison-Behmoaras T., Le Doan T., Puisieux F., Couvreur P., Helene C. Adsorption of oligonucleotides onto polyisohexylcyanoacrylate nanoparticles protects them against nucleases and increases their cellular uptake. Pharm. Res. 11:1994;1370-1378.
    • (1994) Pharm. Res. , vol.11 , pp. 1370-1378
    • Chavany, C.1    Saison-Behmoaras, T.2    Le Doan, T.3    Puisieux, F.4    Couvreur, P.5    Helene, C.6
  • 126
    • 0029983418 scopus 로고    scopus 로고
    • Pharmacokinetics and biodistribution of oligonucleotide adsorbed onto poly(isobutylcyanoacrylate) nanoparticles after intravenous administration in mice
    • Nakada Y., Fattal E., Foulquier M., Couvreur P. Pharmacokinetics and biodistribution of oligonucleotide adsorbed onto poly(isobutylcyanoacrylate) nanoparticles after intravenous administration in mice. Pharm. Res. 13:1996;38-43.
    • (1996) Pharm. Res. , vol.13 , pp. 38-43
    • Nakada, Y.1    Fattal, E.2    Foulquier, M.3    Couvreur, P.4
  • 127
    • 0028037219 scopus 로고
    • Antisense oligonucleotides adsorbed to polyalkylcyanoacrylate nanoparticles specifically inhibit mutated Ha-ras-mediated cell proliferation and tumorigenicity in nude mice
    • Schwab G., Chavany C., Duroux I., Goubin G., Lebeau J., Helene C., Saison-Behmoaras T. Antisense oligonucleotides adsorbed to polyalkylcyanoacrylate nanoparticles specifically inhibit mutated Ha-ras-mediated cell proliferation and tumorigenicity in nude mice. Proc. Natl. Acad. Sci. USA. 91:1994;10460-10464.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 10460-10464
    • Schwab, G.1    Chavany, C.2    Duroux, I.3    Goubin, G.4    Lebeau, J.5    Helene, C.6    Saison-Behmoaras, T.7
  • 128
    • 0032293435 scopus 로고    scopus 로고
    • Effect of polyisobutylcyanoacrylate nanoparticles and lipofectin loaded with oligonucleotides on cell viability and PKC alpha neosynthesis in HepG2 cells
    • Lambert G., Fattal E., Brehier A., Feger J., Couvreur P. Effect of polyisobutylcyanoacrylate nanoparticles and lipofectin loaded with oligonucleotides on cell viability and PKC alpha neosynthesis in HepG2 cells. Biochimie. 80:1998;969-976.
    • (1998) Biochimie , vol.80 , pp. 969-976
    • Lambert, G.1    Fattal, E.2    Brehier, A.3    Feger, J.4    Couvreur, P.5
  • 129
    • 0035910876 scopus 로고    scopus 로고
    • Polyisobutylcyanoacrylate nanocapsules containing an aqueous core for the delivery of oligonucleotides
    • Lambert G., Fattal E., Pinto-Alphandary H., Gulik A., Couvreur P. Polyisobutylcyanoacrylate nanocapsules containing an aqueous core for the delivery of oligonucleotides. Int. J. Pharm. 214:2001;13-16.
    • (2001) Int. J. Pharm. , vol.214 , pp. 13-16
    • Lambert, G.1    Fattal, E.2    Pinto-Alphandary, H.3    Gulik, A.4    Couvreur, P.5
  • 131
    • 0031025207 scopus 로고    scopus 로고
    • EWS-Fli1 antisense oligodeoxynucleotide inhibits proliferation of human Ewing's sarcoma and primitive neuroectodermal tumor cells
    • Tanaka K., Iwakuma T., Harimaya K., Sato H., Iwamoto Y. EWS-Fli1 antisense oligodeoxynucleotide inhibits proliferation of human Ewing's sarcoma and primitive neuroectodermal tumor cells. J. Clin. Invest. 99:1997;239-247.
    • (1997) J. Clin. Invest. , vol.99 , pp. 239-247
    • Tanaka, K.1    Iwakuma, T.2    Harimaya, K.3    Sato, H.4    Iwamoto, Y.5
  • 132
    • 0029943679 scopus 로고    scopus 로고
    • Phosphorothioate antisense oligodeoxynucleotides: Questions of specificity
    • Stein C.A. Phosphorothioate antisense oligodeoxynucleotides: questions of specificity. Biotechnology. 14:1996;47-149.
    • (1996) Biotechnology , vol.14 , pp. 47-149
    • Stein, C.A.1
  • 133
    • 0035937595 scopus 로고    scopus 로고
    • Nanoparticulate systems for brain delivery of drugs
    • Kreuter J. Nanoparticulate systems for brain delivery of drugs. Adv. Drug Deliv. Rev. 47:2001;65-81.
    • (2001) Adv. Drug Deliv. Rev. , vol.47 , pp. 65-81
    • Kreuter, J.1
  • 134
    • 0028911362 scopus 로고
    • Passage of peptides through the blood-brain barrier with colloidal polymer particles (nanoparticles)
    • Kreuter J., Alyautdin R.N., Kharkevich D.A., Ivanov A.A. Passage of peptides through the blood-brain barrier with colloidal polymer particles (nanoparticles). Brain Res. 674:1995;171-174.
    • (1995) Brain Res. , vol.674 , pp. 171-174
    • Kreuter, J.1    Alyautdin, R.N.2    Kharkevich, D.A.3    Ivanov, A.A.4
  • 135
    • 0030993566 scopus 로고    scopus 로고
    • Delivery of loperamide across the blood-brain barrier with polysorbate 80-coated polybutylcyanoacrylate nanoparticles
    • Alyautdin R.N., Petrov V.E., Langer K., Berthold A., Kharkevich D.A., Kreuter J. Delivery of loperamide across the blood-brain barrier with polysorbate 80-coated polybutylcyanoacrylate nanoparticles. Pharm. Res. 14:1997;325-328.
    • (1997) Pharm. Res. , vol.14 , pp. 325-328
    • Alyautdin, R.N.1    Petrov, V.E.2    Langer, K.3    Berthold, A.4    Kharkevich, D.A.5    Kreuter, J.6
  • 136
    • 0031962120 scopus 로고    scopus 로고
    • Significant entry of tubocurarine into the brain of rats by adsorption to polysorbate 80-coated polybutylcyanoacrylate nanoparticles: An in situ brain perfusion study
    • Alyautdin R.N., Tezikov E.B., Ramge P., Kharkevich D.A., Begley D.J., Kreuter J. Significant entry of tubocurarine into the brain of rats by adsorption to polysorbate 80-coated polybutylcyanoacrylate nanoparticles: an in situ brain perfusion study. J. Microencapsul. 15:1998;67-74.
    • (1998) J. Microencapsul. , vol.15 , pp. 67-74
    • Alyautdin, R.N.1    Tezikov, E.B.2    Ramge, P.3    Kharkevich, D.A.4    Begley, D.J.5    Kreuter, J.6
  • 137
    • 0033993565 scopus 로고    scopus 로고
    • Increase of the duration of the anticonvulsive activity of a novel NMDA receptor antagonist using poly(butylcyanoacrylate) nanoparticles as a parenteral controlled release system
    • Friese A., Seiller E., Quack G., Lorenz B., Kreuter J. Increase of the duration of the anticonvulsive activity of a novel NMDA receptor antagonist using poly(butylcyanoacrylate) nanoparticles as a parenteral controlled release system. Eur. J. Pharm. Biopharm. 49:2000;103-109.
    • (2000) Eur. J. Pharm. Biopharm. , vol.49 , pp. 103-109
    • Friese, A.1    Seiller, E.2    Quack, G.3    Lorenz, B.4    Kreuter, J.5
  • 138
    • 0036196112 scopus 로고    scopus 로고
    • Neuroprotective activity of a nanoparticulate formulation of the glycine B site antagonist MRZ 2/576 in transient focal ischaemia in rats
    • Sopala M., Schweizer S., Schafer N., Nurnberg E., Kreuter J., Seiller E., Danysz W. Neuroprotective activity of a nanoparticulate formulation of the glycine B site antagonist MRZ 2/576 in transient focal ischaemia in rats. Arzneimittelforschung. 52:2002;168-174.
    • (2002) Arzneimittelforschung , vol.52 , pp. 168-174
    • Sopala, M.1    Schweizer, S.2    Schafer, N.3    Nurnberg, E.4    Kreuter, J.5    Seiller, E.6    Danysz, W.7
  • 139
  • 140
    • 0037168963 scopus 로고    scopus 로고
    • Toxicological studies of doxorubicin bound to polysorbate 80-coated poly(butyl cyanoacrylate) nanoparticles in healthy rats and rats with intracranial glioblastoma
    • Gelperina S.E., Khalansky A.S., Skidan I.N., Smirnova Z.S., Bobruskin A.I., Severin S.E., Turowski B., Zanella F.E., Kreuter J. Toxicological studies of doxorubicin bound to polysorbate 80-coated poly(butyl cyanoacrylate) nanoparticles in healthy rats and rats with intracranial glioblastoma. Toxicol. Lett. 126:2002;131-141.
    • (2002) Toxicol. Lett. , vol.126 , pp. 131-141
    • Gelperina, S.E.1    Khalansky, A.S.2    Skidan, I.N.3    Smirnova, Z.S.4    Bobruskin, A.I.5    Severin, S.E.6    Turowski, B.7    Zanella, F.E.8    Kreuter, J.9
  • 141
    • 0034118297 scopus 로고    scopus 로고
    • Polysorbate-80 coating enhances uptake of polybutylcyanoacrylate (PBCA)-nanoparticles by human and bovine primary brain capillary endothelial cells
    • Ramge P., Unger R.E., Oltrogge J.B., Zenker D., Begley D., Kreuter J., Von Briesen H. Polysorbate-80 coating enhances uptake of polybutylcyanoacrylate (PBCA)-nanoparticles by human and bovine primary brain capillary endothelial cells. Eur. J. Neurosci. 12:2000;1931-1940.
    • (2000) Eur. J. Neurosci. , vol.12 , pp. 1931-1940
    • Ramge, P.1    Unger, R.E.2    Oltrogge, J.B.3    Zenker, D.4    Begley, D.5    Kreuter, J.6    Von Briesen, H.7
  • 142
    • 0034887157 scopus 로고    scopus 로고
    • Interaction of poly(butylcyanoacrylate) nanoparticles with the blood-brain barrier in vivo and in vitro
    • Alyaudtin R.N., Reichel A., Lobenberg R., Ramge P., Kreuter J., Begley D.J. Interaction of poly(butylcyanoacrylate) nanoparticles with the blood-brain barrier in vivo and in vitro. J. Drug Target. 9:2001;209-221.
    • (2001) J. Drug Target. , vol.9 , pp. 209-221
    • Alyaudtin, R.N.1    Reichel, A.2    Lobenberg, R.3    Ramge, P.4    Kreuter, J.5    Begley, D.J.6
  • 143
    • 0345280812 scopus 로고    scopus 로고
    • Influence of the surfactant concentration on the body distribution of nanoparticles
    • Araujo L., Lobenberg R., Kreuter J. Influence of the surfactant concentration on the body distribution of nanoparticles. J. Drug Target. 6:1999;373-385.
    • (1999) J. Drug Target. , vol.6 , pp. 373-385
    • Araujo, L.1    Lobenberg, R.2    Kreuter, J.3
  • 144
    • 0033427851 scopus 로고    scopus 로고
    • Indirect evidence that drug brain targeting using polysorbate 80-coated polybutylcyanoacrylate nanoparticles is related to toxicity
    • Olivier J.C., Fenart L., Chauvet R., Pariat C., Cecchelli R., Couet W. Indirect evidence that drug brain targeting using polysorbate 80-coated polybutylcyanoacrylate nanoparticles is related to toxicity. Pharm. Res. 16:1999;1836-1842.
    • (1999) Pharm. Res. , vol.16 , pp. 1836-1842
    • Olivier, J.C.1    Fenart, L.2    Chauvet, R.3    Pariat, C.4    Cecchelli, R.5    Couet, W.6
  • 145
    • 0036460265 scopus 로고    scopus 로고
    • Quantification and localization of PEGylated polycyanoacrylate nanoparticles in brain and spinal cord during experimental allergic encephalomyelitis in the rat
    • Calvo P., Gouritin B., Villarroya H., Eclancher F., Giannavola C., Klein C., Andreux J.P., Couvreur P. Quantification and localization of PEGylated polycyanoacrylate nanoparticles in brain and spinal cord during experimental allergic encephalomyelitis in the rat. Eur. J. Neurosci. 15:2002;1317-1326.
    • (2002) Eur. J. Neurosci. , vol.15 , pp. 1317-1326
    • Calvo, P.1    Gouritin, B.2    Villarroya, H.3    Eclancher, F.4    Giannavola, C.5    Klein, C.6    Andreux, J.P.7    Couvreur, P.8
  • 146
    • 0024953407 scopus 로고
    • The uptake and translocation of latex nanospheres and microspheres after oral administration to rats
    • Jani P., Halbert G.W., Langridge J., Florence A.T. The uptake and translocation of latex nanospheres and microspheres after oral administration to rats. J. Pharm. Pharmacol. 41:1989;809-812.
    • (1989) J. Pharm. Pharmacol. , vol.41 , pp. 809-812
    • Jani, P.1    Halbert, G.W.2    Langridge, J.3    Florence, A.T.4
  • 147
    • 0021858721 scopus 로고
    • Retention of ingested latex particles in Peyers patches of gerinfree and conventional mice
    • Le Fevre H.E., Joel D.D., Shidlousky G. Retention of ingested latex particles in Peyers patches of gerinfree and conventional mice. Soc. Exp. Biol. Med. 179:1985;522-528.
    • (1985) Soc. Exp. Biol. Med. , vol.179 , pp. 522-528
    • Le Fevre, H.E.1    Joel, D.D.2    Shidlousky, G.3
  • 149
    • 0035478442 scopus 로고    scopus 로고
    • Transcytosis of nanoparticle and dendrimer delivery systems: Evolving vistas
    • Florence A.T., Hussain N. Transcytosis of nanoparticle and dendrimer delivery systems: evolving vistas. Adv. Drug Deliv. Rev. 50:2001;S69-S89.
    • (2001) Adv. Drug Deliv. Rev. , vol.50
    • Florence, A.T.1    Hussain, N.2
  • 150
    • 0024443602 scopus 로고
    • Quantitative and microautoradiographic study on mouse intestinal distribution of polycyanoacrylate nanoparticles
    • Kreuter J., Muller V., Munz K. Quantitative and microautoradiographic study on mouse intestinal distribution of polycyanoacrylate nanoparticles. Int. J. Pharm. 55:1989;39-45.
    • (1989) Int. J. Pharm. , vol.55 , pp. 39-45
    • Kreuter, J.1    Muller, V.2    Munz, K.3
  • 151
    • 0023578342 scopus 로고
    • Transmucosal passage of polyalkylcyanoacrylate nanocapsules as a new drug carrier in the small intestine
    • Aprahamian M., Michel C., Humbert W., Devissaguet J.P., Damge C. Transmucosal passage of polyalkylcyanoacrylate nanocapsules as a new drug carrier in the small intestine. Biol. Cell. 61:1987;69-76.
    • (1987) Biol. Cell , vol.61 , pp. 69-76
    • Aprahamian, M.1    Michel, C.2    Humbert, W.3    Devissaguet, J.P.4    Damge, C.5
  • 153
    • 0031446134 scopus 로고    scopus 로고
    • Poly(alkyl cyanoacrylate) nanospheres for oral administration of insulin
    • Damge C., Vranckx H., Balschmidt P., Couvreur P. Poly(alkyl cyanoacrylate) nanospheres for oral administration of insulin. J. Pharm. Sci. 86:1997;1403-1409.
    • (1997) J. Pharm. Sci. , vol.86 , pp. 1403-1409
    • Damge, C.1    Vranckx, H.2    Balschmidt, P.3    Couvreur, P.4
  • 154
    • 0036222307 scopus 로고    scopus 로고
    • In-vitro release and oral bioavailability in diabetic rats of insulin using nanocapsules dispersed in biocompatible microemulsion
    • Watnasirichaikul S., Rades T., Tucker I.G., Davies N.M. In-vitro release and oral bioavailability in diabetic rats of insulin using nanocapsules dispersed in biocompatible microemulsion. J. Pharm. Pharmacol. 54:2002;473-480.
    • (2002) J. Pharm. Pharmacol. , vol.54 , pp. 473-480
    • Watnasirichaikul, S.1    Rades, T.2    Tucker, I.G.3    Davies, N.M.4
  • 155
    • 0030691084 scopus 로고    scopus 로고
    • Poly(alkyl cyanoacrylate) nanocapsules as a delivery system in the rat for octreotide, a long-acting somatostatin analogue
    • Damge C., Vonderscher J., Marbach P., Pinget M. Poly(alkyl cyanoacrylate) nanocapsules as a delivery system in the rat for octreotide, a long-acting somatostatin analogue. J. Pharm. Pharmacol. 49:1997;949-954.
    • (1997) J. Pharm. Pharmacol. , vol.49 , pp. 949-954
    • Damge, C.1    Vonderscher, J.2    Marbach, P.3    Pinget, M.4
  • 156
    • 0034087415 scopus 로고    scopus 로고
    • Transmucosal delivery systems for calcitonin: A review
    • Torres-Lugo M., Peppas N.A. Transmucosal delivery systems for calcitonin: a review. Biomaterials. 21:2000;1191-1196.
    • (2000) Biomaterials , vol.21 , pp. 1191-1196
    • Torres-Lugo, M.1    Peppas, N.A.2
  • 157
    • 0024380946 scopus 로고
    • Poly(butyl-2-cyanoacrylate) particles as adjuvant for oral immunization
    • O'Hagan D.T., Palin K., Davis S.S. Poly(butyl-2-cyanoacrylate) particles as adjuvant for oral immunization. Vaccine. 7:1989;213-216.
    • (1989) Vaccine , vol.7 , pp. 213-216
    • O'Hagan, D.T.1    Palin, K.2    Davis, S.S.3
  • 158
    • 0023235537 scopus 로고
    • Bioadhesive analysis of the controlled-release systems. III. Fracture and interpenetration analysis in poly(acrylic acid) containing systems
    • Ponchel G., Touchard F., Duchene D., Peppas N.A. Bioadhesive analysis of the controlled-release systems. III. Fracture and interpenetration analysis in poly(acrylic acid) containing systems. J. Control. Release. 5:1987;129-141.
    • (1987) J. Control. Release , vol.5 , pp. 129-141
    • Ponchel, G.1    Touchard, F.2    Duchene, D.3    Peppas, N.A.4
  • 159
    • 0032403467 scopus 로고    scopus 로고
    • Specific and non-specific bioadhesive particulate systems for oral delivery to the gastrointestinal tract
    • Ponchel G., Irache J. Specific and non-specific bioadhesive particulate systems for oral delivery to the gastrointestinal tract. Adv. Drug Deliv. Rev. 34:1998;191-219.
    • (1998) Adv. Drug Deliv. Rev. , vol.34 , pp. 191-219
    • Ponchel, G.1    Irache, J.2
  • 160
    • 0035937594 scopus 로고    scopus 로고
    • Mucoadhesive nanoparticulate systems for peptide drug delivery
    • Takeuchi H., Yamamoto H., Kawashima Y.Y. Mucoadhesive nanoparticulate systems for peptide drug delivery. Adv. Drug Deliv. Rev. 47:2001;39-54.
    • (2001) Adv. Drug Deliv. Rev. , vol.47 , pp. 39-54
    • Takeuchi, H.1    Yamamoto, H.2    Kawashima, Y.Y.3
  • 161
    • 0026531651 scopus 로고
    • Effect of various poloxamer coatings on in vitro adhesion of isohexylcyanoacrylate nanospheres to rat ileal segments under liquid flow
    • Pimienta C., Chouinard F., Labib A., Lenaerts V. Effect of various poloxamer coatings on in vitro adhesion of isohexylcyanoacrylate nanospheres to rat ileal segments under liquid flow. Int. J. Pharm. 80:1992;1-8.
    • (1992) Int. J. Pharm. , vol.80 , pp. 1-8
    • Pimienta, C.1    Chouinard, F.2    Labib, A.3    Lenaerts, V.4
  • 162
    • 0012950243 scopus 로고
    • Nanoparticles as a gastrointestinal drug delivery system
    • V. Lenaerts, & R. Gurny. Boca Raton, FL: CRC Press
    • Lenaerts V., Couvreur P., Grislain L., Maincent P. Nanoparticles as a gastrointestinal drug delivery system. Lenaerts V., Gurny R. Bioadhesive Drug Delivery Systems. 1990;94-104 CRC Press, Boca Raton, FL.
    • (1990) Bioadhesive Drug Delivery Systems , pp. 94-104
    • Lenaerts, V.1    Couvreur, P.2    Grislain, L.3    Maincent, P.4
  • 163
    • 0022966767 scopus 로고
    • Disposition kinetics and oral bioavailability of vincamine-loaded polyalkyl cyanoacrylate nanoparticles
    • Maincent P., Le Verge R., Sado P., Couvreur P., Devissaguet J.P. Disposition kinetics and oral bioavailability of vincamine-loaded polyalkyl cyanoacrylate nanoparticles. J. Pharm. Sci. 75:1986;955-958.
    • (1986) J. Pharm. Sci. , vol.75 , pp. 955-958
    • Maincent, P.1    Le Verge, R.2    Sado, P.3    Couvreur, P.4    Devissaguet, J.P.5
  • 165
    • 0025854457 scopus 로고
    • The preparation and acute antihypertensive effects of a nanocapsular form of darodipine, a dihydropyridine calcium entry blocker
    • Hubert B., Atkinson J., Guerret M., Hoffman M., Devissaguet J.P., Maincent P. The preparation and acute antihypertensive effects of a nanocapsular form of darodipine, a dihydropyridine calcium entry blocker. Pharm. Res. 8:1991;734-738.
    • (1991) Pharm. Res. , vol.8 , pp. 734-738
    • Hubert, B.1    Atkinson, J.2    Guerret, M.3    Hoffman, M.4    Devissaguet, J.P.5    Maincent, P.6
  • 168
    • 0025937924 scopus 로고
    • Studies on the transport pathway of PBCA nanoparticles in ocular tissues
    • Zimmer A., Kreuter J., Robinson J.R. Studies on the transport pathway of PBCA nanoparticles in ocular tissues. J. Microencapsul. 8:1991;497-504.
    • (1991) J. Microencapsul. , vol.8 , pp. 497-504
    • Zimmer, A.1    Kreuter, J.2    Robinson, J.R.3
  • 170
    • 0034303241 scopus 로고    scopus 로고
    • Pluronic F127-based ocular delivery systems containing biodegradable polyisobutylcyanoacrylate nanocapsules of pilocarpine
    • Desai S.D., Blanchard J. Pluronic F127-based ocular delivery systems containing biodegradable polyisobutylcyanoacrylate nanocapsules of pilocarpine. J. Deliv. Target. Ther. Agents. 7:2000;201-207.
    • (2000) J. Deliv. Target. Ther. Agents , vol.7 , pp. 201-207
    • Desai, S.D.1    Blanchard, J.2
  • 171
    • 0035090503 scopus 로고    scopus 로고
    • Ocular tolerability and in vivo bioavailability of poly(ethylene glycol) (PEG)-coated polyethyl-2-cyanoacrylate nanospheres-encapsulated acyclovir
    • Fresta M., Fontana G., Bucolo C., Cavallaro G., Giammona G., Puglisi G. Ocular tolerability and in vivo bioavailability of poly(ethylene glycol) (PEG)-coated polyethyl-2-cyanoacrylate nanospheres-encapsulated acyclovir. J. Pharm. Sci. 90:2001;288-297.
    • (2001) J. Pharm. Sci. , vol.90 , pp. 288-297
    • Fresta, M.1    Fontana, G.2    Bucolo, C.3    Cavallaro, G.4    Giammona, G.5    Puglisi, G.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.