Interactions of poly(lactic acid) and poly(lactic acid-co-ethylene oxide) nanoparticles with the plasma factors of the coagulation system

Biomaterials

Volumn 18, Issue 4, 1997, Pages 281-288

  Sahli, Hamid ^b   Tapon Bretaudière, Jacqueline ^b   Fischer, Anne Marie ^b   Sternberg, Claude ^b   Spenlehauer, Gilles ^c   Verrecchia, Thierry ^c   Labarre, Denis ^a  

^a UNIV PARIS SUD   (France)

^b HÔPITAL NECKER ENFANTS MALADES   (France)

^c Departement de Sci Pharmaceutiques   (France)

Author keywords

Coagulation factors; Drug carriers; Nanoparticles; Poly(lactic acid); Poly(lactic acid co ethylene oxide); Steric repulsion

Indexed keywords

BIOPOLYMERS; BLOOD; COAGULATION; DRUG INTERACTIONS; NANOSTRUCTURED MATERIALS; PARTICLES (PARTICULATE MATTER); PROTEINS; SURFACE ACTIVE AGENTS; SUSPENSIONS (FLUIDS);

COAGULATION CASCADES; DRUG CARRIERS; NANOPARTICLE SUSPENSIONS; PLASMA FACTORS; PLATELET POOR PLASMA; POLYLACTIC ACID; POLYLACTIC ACID COETHYLENE OXIDE; STERIC REPULSION;

BIOMATERIALS;

CHOLIC ACID; DRUG CARRIER; NANOPARTICLE; POLYLACTIC ACID;

ARTICLE; BLOOD CLOTTING; BLOOD CLOTTING TIME; CLEARANCE; DRUG CLEARANCE; DRUG TRANSPORT; PLASMA FACTOR; PRIORITY JOURNAL; SUSPENSION;

BLOOD COAGULATION; BLOOD COAGULATION FACTORS; BLOOD PROTEINS; CALCIUM; CHEMISTRY, PHYSICAL; HUMANS; LACTIC ACID; PARTICLE SIZE; PHOSPHOLIPIDS; POLYETHYLENE GLYCOLS; POLYMERS; SUSPENSIONS; THROMBIN;

EID: 0031081070     PISSN: 01429612     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0142-9612(96)00146-9     Document Type: Article

References (10)

1. 1. Vittaz, M., Bazile, D., Spenlehauer, G., Verrecchia, T., Veillard, M., Puisieux, F. and Labarre, D., Effect of PEO surface density on long-circulating PLA-PEO nanoparticles which are very low complement activators. Biomaterials, 1996, 17, 1515-1581.
2. 2. Verrecchia, T., Spenlehauer, G., Bazile, D.V., Murry-Brelier, A., Archimbaud, Y. and Veillard, M., Nonstealth poly(lactic acid/albumin) and stealth poly(lactic acid-polyethylene glycol) nanoparticles as injectable drug carriers. J Controlled Release, 1995, 36, 49-61.
3. 3. Bazile, D., Michalon, J. P., Prud'homme, C., Spenlehauer, G. and Veillard, M., Nanoparticules ayant un temps de capture par le système réticulo-endothélial allongé. French Patent 08,041, 1991.
4. 4. Bazile, D., Prud'homme, C., Bassoullet, M. T., Marlard, M., Spenlehauer, G. and Veillard, M., Stealth Me.PEG-PLA nanoparticles avoid uptake by the mononuclear phagocytes system. J Pharm Sci, 1995, 84, 493-498.
5. 5. Gref, R., Minamitake, Y., Peracchia, M. T., Trubetskoy, V., Torchilin, V. and Langer, R., Biodegradable long-circulating polymeric nanospheres. Science, 1994, 263, 1600-1603.
6. 6. Jeon, S. I., Lee, J. H., Andrade, J. D. and De Gennes, P. G., Protein-surface interactions in the presence of polyethylene oxide; 1. Simplified theory. J Colloid Interf Sci, 1991, 142, 149-158.
7. 7. Jeon, S.I. and Andrade, J.D., Protein-surface interactions in the presence of polyethylene oxide; 2. Effect of protein size. J Colloid Interf Sci, 1991, 142, 159-166.
8. 8. Baleux, B., Dosage colorimétrique d'agents de surface non ioniques polyoxyéthylène à l'aide d'une solution iodo-iodurée. CR Acad Sci Paris, 1972, 274, C1617-C1619.
9. 9. Sims, G. E. E. and Snape, T. J. A., Method for the estimation of polyethylene glycol in plasma protein fractions. Anal Biochem, 1980, 107, 60-63.
10. 10. Laurell, C.B., Quantitative estimation of proteins by electrophoresis in agarose gels containing antibodies. Anal Biochem, 1966, 15, 45-52.