Proteomics-based allergen analysis in plants

Journal of Proteomics

Volumn 93, Issue , 2013, Pages 40-49

  Nakamura, Rika ^a   Teshima, Reiko ^a  

^a NATIONAL INSTITUTE OF HEALTH SCIENCES   (Japan)

Author keywords

Allergenomics; Allergens; Genetically modified foods; IgE; Plant proteomics

Indexed keywords

ALLERGEN; AMINE; AMYLASE INHIBITOR; ARA H 2 PROTEIN; ARA H PROTEIN; AVENIN; BETA AMYLASE; ELONGATION FACTOR 2; ENOLASE; FRUCTOSE BISPHOSPHATE ALDOLASE; GLIADIN; GLUTENIN; HEAT SHOCK PROTEIN; IMMUNOGLOBULIN E; ISOFLAVONE; MALATE DEHYDROGENASE; OVOMUCOID; PEPTIDYLPROLYL ISOMERASE; POLYGALACTURONASE; POLYVINYLIDENE FLUORIDE; PROFILIN; PROTEINASE; PROTEINASE INHIBITOR; SERINE PROTEINASE INHIBITOR; THIOREDOXIN; THIOREDOXIN H; TRYPSIN INHIBITOR; UNCLASSIFIED DRUG; UNINDEXED DRUG; VEGETABLE PROTEIN; VICILIN;

ALLERGENICITY; ALLERGIC REACTION; ALMOND; AMINO ACID SEQUENCE; BERMUDA; CROSS REACTION; CUPRESSUS; EXPRESSED SEQUENCE TAG; FRUIT; GEL CHROMATOGRAPHY; GRASS POLLEN; HAZELNUT; IMMUNOBLOTTING; IMMUNOCHEMISTRY; ISOELECTRIC FOCUSING; LIQUID CHROMATOGRAPHY; MAIZE; MASS SPECTROMETRY; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; MILK; NONHUMAN; PEANUT; PHOENIX (PLANT); PLANT GENETICS; POLYACRYLAMIDE GEL ELECTROPHORESIS; POTATO; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN MICROARRAY; PROTEOMICS; RADIOALLERGOSORBENT TEST; REVIEW; RICE; SEQUENCE ANALYSIS; SEQUOIA; SESAME; SOYBEAN; SWEET ORANGE; TOMATO; WALNUT; WHEAT;

ALLERGENOMICS; ALLERGENS; GENETICALLY MODIFIED FOODS; IGE; PLANT PROTEOMICS;

ALLERGENS; ANTIGENS, PLANT; FOOD HYPERSENSITIVITY; HUMANS; HYPERSENSITIVITY; IMMUNOGLOBULIN E; MASS SPECTROMETRY; MAST CELLS; PLANTS, GENETICALLY MODIFIED; POLLEN; PROTEOMICS;

EID: 84888022500     PISSN: 18743919     EISSN: 18767737     Source Type: Journal    
DOI: 10.1016/j.jprot.2013.03.018     Document Type: Review

References (91)

1. Cianferoni A., Muraro A. Food-induced anaphylaxis. Immunol Allergy Clin North Am 2012, 32:165-195.
2. Holowka D., Baird B. Antigen-mediated IgE receptor aggregation and signaling. Annu Rev Biophys Biomol Struct 1996, 25:79-112.
3. Akagawa M., Handoyo T., Ishii T., Kumazawa S., Morita N., Suyama K. Proteomic analysis of wheat flour allergens. J Agric Food Chem 2007, 55:6863-6870.
4. Yagami T., Haishima Y., Tsuchiya T., Tomitaka-Yagami A., Kano H., Matsunaga K. Proteomic analysis of putative latex allergens. Int Arch Allergy Immunol 2004, 135:3-11.
5. Picariello G., Mamone G., Addeo F., Ferranti P. The frontiers of mass spectrometry-based techniques in food allergenomics. J Chromatogr A 2011, 1218:7386-7398.
6. Wagner S., Radauer C., Bublin M., Hoffmann-Sommergruber K., Kopp T., Greisenegger E.K., et al. Naturally occurring hypoallergenic Bet v 1 isoforms fail to induce IgE responses in individuals with birch pollen allergy. J Allergy Clin Immunol 2008, 121:246-252.
7. Shahali Y., Sutra J.P., Haddad I., Vinh J., Guilloux L., Peltre G., et al. Proteomics of cypress pollen allergens using double and triple one-dimensional electrophoresis. Electrophoresis 2012, 33:462-469.
8. Kitta K., Ohnishi-Kameyama M., Moriyama T., Ogawa T., Kawamoto S. Detection of low-molecular weight allergens resolved on two-dimensional electrophoresis with acid-urea polyacrylamide gel. Anal Biochem 2006, 351:290-297.
9. Yano H., Kuroda S. Introduction of the disulfide proteome: application of a technique for the analysis of plant storage proteins as well as allergens. J Proteome Res 2008, 7:3071-3079.
10. Pastorello E.A., Pompei C., Pravettoni V., Brenna O., Farioli L., Trambaioli C., et al. Lipid transfer proteins and 2S albumins as allergens. Allergy 2001, 56(Suppl. 67):45-47.
11. Breiteneder H., Mills E.N. Molecular properties of food allergens. J Allergy Clin Immunol 2005, 115:14-23.
12. Radauer C., Breiteneder H. Evolutionary biology of plant food allergens. J Allergy Clin Immunol 2007, 120:518-525.
13. Breiteneder H., Radauer C. A classification of plant food allergens. J Allergy Clin Immunol 2004, 113:821-830.
14. Yagami T. Allergies to cross-reactive plant proteins. Latex-fruit syndrome is comparable with pollen-food allergy syndrome. Int Arch Allergy Immunol 2002, 128:271-279.
15. Kondo Y., Urisu A. Oral allergy syndrome. Allergol Int 2009, 58:485-491.
16. Ebisawa M., Ikematsu K., Imai T., Tachimoto H. Food allergy in Japan. J World Allergy Organ 2003, 15:214-217.
17. Jaggi K.S., Gangal S.V. Isolation and identification of pollen allergens of Artemisia scoparia. J Allergy Clin Immunol 1987, 80:562-572.
18. Gad El Rab M.O., Thatcher D.R., Kay A.B. Widespread IgE-mediated hypersensitivity in the Sudan to the 'green nimitti' midge, Cladotanytarsus lewisi (Diptera: Chironomidae) II. Identification of a major allergen. Clin Exp Immunol 1980, 41:389-396.
19. Bleumink E., Berrens L., Young E. Studies on the atopic allergen in ripe tomato fruits. I. Isolation and identification of the allergen. Int Arch Allergy Appl Immunol 1966, 30:132-145.
20. Beyer K., Grishina G., Bardina L., Grishin A., Sampson H.A. Identification of an 11S globulin as a major hazelnut food allergen in hazelnut-induced systemic reactions. J Allergy Clin Immunol 2002, 110:517-523.
21. Boldt A., Fortunato D., Conti A., Petersen A., Ballmer-Weber B., Lepp U., et al. Analysis of the composition of an immunoglobulin E reactive high molecular weight protein complex of peanut extract containing Ara h 1 and Ara h 3/4. Proteomics 2005, 5:675-686.
22. Postigo I., Guisantes J.A., Negro J.M., Rodríguez-Pacheco R., David-García D., Martínez J. Identification of 2 new allergens of Phoenix dactylifera using an immunoproteomics approach. J Investig Allergol Clin Immunol 2009, 19:504-507.
23. Porterfield H.S., Murray K.S., Schlichting D.G., Chen X., Hansen K.C., Duncan M.W., et al. Effector activity of peanut allergens: a critical role for Ara h 2, Ara h 6, and their variants. Clin Exp Allergy 2009, 39:1099-1108.
24. Sotkovský P., Hubálek M., Hernychová L., Novák P., Havranová M., Setinová I., et al. Proteomic analysis of wheat proteins recognized by IgE antibodies of allergic patients. Proteomics 2008, 8:1677-1691.
25. Satoh R., Nakamura R., Komatsu A., Oshima M., Teshima R. Proteomic analysis of known and candidate rice allergens between non-transgenic and transgenic plants. Regul Toxicol Pharmacol 2011, 59:437-444.
26. Guo B., Liang X., Chung S.Y., Holbrook C.C., Maleki S.J. Proteomic analysis of peanut seed storage proteins and genetic variation in a potential peanut allergen. Protein Pept Lett 2008, 15:567-577.
27. Raftery M.J., Saldanha R.G., Geczy C.L., Kumar R.K. Mass spectrometric analysis of electrophoretically separated allergens and proteases in grass pollen diffusates. Respir Res 2003, 4:10.
28. Sheoran I.S., Ross A.R., Olson D.J., Sawhney V.K. Proteomic analysis of tomato (Lycopersicon esculentum) pollen. J Exp Bot 2007, 58:3525-3535.
29. De Canio M., D'Aguanno S., Sacchetti C., Petrucci F., Cavagni G., Nuccetelli M., et al. Novel IgE recognized components of Lolium perenne pollen extract: comparative proteomics evaluation of allergic patients sensitization profiles. J Proteome Res 2009, 8:4383-4391.
30. Kao S.H., Su S.N., Huang S.W., Tsai J.J., Chow L.P. Sub-proteome analysis of novel IgE-binding proteins from Bermuda grass pollen. Proteomics 2005, 5:3805-3813.
31. Hjernø K., Alm R., Canbäck B., Matthiesen R., Trajkovski K., Björk L., et al. Down-regulation of the strawberry Bet v 1-homologous allergen in concert with the flavonoid biosynthesis pathway in colorless strawberry mutant. Proteomics 2006, 6:1574-1587.
32. Alm R., Ekefjärd A., Krogh M., Häkkinen J., Emanuelsson C. Proteomic variation is as large within as between strawberry varieties. J Proteome Res 2007, 6:3011-3020.
33. Reuter A., Fortunato D., Garoffo L.P., Napolitano L., Scheurer S., Giuffrida M.G., et al. Novel isoforms of Pru av 1 with diverging immunoglobulin E binding properties identified by a synergistic combination of molecular biology and proteomics. Proteomics 2005, 5:282-289.
34. Pignataro V., Canton C., Spadafora A., Mazzuca S. Proteome from lemon fruit flavedo reveals that this tissue produces high amounts of the Cit s1 germin-like isoforms. J Agric Food Chem 2010, 58:7239-7244.
35. Nakamura R., Uchida Y., Higuchi M., Nakamura R., Tsuge I., Urisu A., et al. A convenient and sensitive allergy test: IgE crosslinking-induced luciferase expression in cultured mast cells. Allergy 2010, 65:1266-1273.
36. D'Amato A., Bachi A., Fasoli E., Boschetti E., Peltre G., Sénéchal H., et al. In-depth exploration of Hevea brasiliensis latex proteome and "hidden allergens" via combinatorial peptide ligand libraries. J Proteomics 2010, 73:1368-1380.
37. Scala E., Alessandri C., Palazzo P., Pomponi D., Liso M., Bernardi M.L., et al. IgE recognition patterns of profilin, PR-10, and tropomyosin panallergens tested in 3,113 allergic patients by allergen microarray-based technology. PLoS One 2011, 6:e24912.
38. Bublin M., Dennstedt S., Buchegger M., Antonietta Ciardiello M., Bernardi M.L., Tuppo L., et al. The performance of a component-based allergen microarray for the diagnosis of kiwifruit allergy. Clin Exp Allergy 2011, 41:129-136.
39. Vigh-Conrad K.A., Conrad D.F., Preuss D. A protein allergen microarray detects specific IgE to pollen surface, cytoplasmic, and commercial allergen extracts. PLoS One 2010, 5:e10174.
40. Constantin C., Quirce S., Poorafshar M., Touraev A., Niggemann B., Mari A., et al. Micro-arrayed wheat seed and grass pollen allergens for component-resolved diagnosis. Allergy 2009, 64:1030-1037.
41. Gadermaier G., Wopfner N., Wallner M., Egger M., Didierlaurent A., Regl G., et al. Array-based profiling of ragweed and mugwort pollen allergens. Allergy 2008, 63:1543-1549.
42. Cretich M., Di Carlo G., Giudici C., Pokoj S., Lauer I., Scheurer S., et al. Detection of allergen specific immunoglobulins by microarrays coupled to microfluidics. Proteomics 2009, 9:2098-2107.
43. Cretich M., Breda D., Damin F., Borghi M., Sola L., Unlu S.M., et al. Allergen microarrays on high-sensitivity silicon slides. Anal Bioanal Chem 2010, 398:1723-1733.
44. Sakai S., Adachi R., Akiyama H., Teshima R. Validation of quantitative and qualitative methods for detecting allergenic ingredients in processed foods in Japan. J Agric Food Chem Oct. 5 2012, [Epub ahead of print].
45. Kirsch S., Fourdrilis S., Dobson R., Scippo M.L., Maghuin-Rogister G., De Pauw E. Quantitative methods for food allergens: a review. Anal Bioanal Chem 2009, 395:57-67.
46. Sakai S., Adachi R., Akiyama H., Teshima R., Doi H., Shibata H. Determination of walnut protein in processed foods by enzyme-linked immunosorbent assay: interlaboratory study. J AOAC Int 2010, 93:1255-1261.
47. Holzhauser T., Stephan O., Vieths S. Detection of potentially allergenic hazelnut (Corylus avellana) residues in food: a comparative study with DNA PCR-ELISA and protein sandwich-ELISA. J Agric Food Chem 2002, 50:5808-5815.
48. Careri M., Mangia A., Musci M. Applications of liquid chromatography-mass spectrometry interfacing systems in food analysis: pesticide, drug and toxic substance residues. J Chromatogr A 1996, 727:153-184.
49. Careri M., Costa A., Elviri L., Lagos J.B., Mangia A., Terenghi M., et al. Use of specific peptide biomarkers for quantitative confirmation of hidden allergenic peanut proteins Ara h 2 and Ara h 3/4 for food control by liquid chromatography-tandem mass spectrometry. Anal Bioanal Chem 2007, 389:1901-1907.
50. Pedreschi R., Nørgaard J., Maquet A. Current challenges in detecting food allergens by shotgun and targeted proteomic approaches: a case study on traces of peanut allergens in baked cookies. Nutrients 2012, 4:132-150.
51. Chassaigne H., Nørgaard J.V., Hengel A.J. Proteomics-based approach to detect and identify major allergens in processed peanuts by capillary LC-Q-TOF (MS/MS). J Agric Food Chem 2007, 55:4461-4473.
52. Newsome G.A., Scholl P.F. Quantification of allergenic bovine milk α(S1)-casein in baked goods using an intact (15)N-labeled protein internal standard. J Agric Food Chem 2013, [in press].
53. Ansari P., Stoppacher N., Rudolf J., Schuhmacher R., Baumgartner S. Selection of possible marker peptides for the detection of major ruminant milk proteins in food by liquid chromatography-tandem mass spectrometry. Anal Bioanal Chem 2011, 399:1105-1115.
54. Lutter P., Parisod V., Weymuth H. Development and validation of a method for the quantification of milk proteins in food products based on liquid chromatography with mass spectrometric detection. J AOAC Int 2011, 94:1043-1059.
55. Lee J.Y., Kim C.J. Determination of allergenic egg proteins in food by protein-, mass spectrometry-, and DNA-based methods. J AOAC Int 2010, 93:462-477.
56. Houston N.L., Lee D.G., Stevenson S.E., Ladics G.S., Bannon G.A., McClain S., et al. Quantitation of soybean allergens using tandem mass spectrometry. J Proteome Res 2011, 10:763-773.
57. Heick J., Fischer M., Kerbach S., Tamm U., Popping B. Application of a liquid chromatography tandem mass spectrometry method for the simultaneous detection of seven allergenic foods in flour and bread and comparison of the method with commercially available ELISA test kits. J AOAC Int 2011, 94:1060-1068.
58. Downs M.L., Taylor S.L. Effects of thermal processing on the enzyme-linked immunosorbent assay (ELISA) detection of milk residues in a model food matrix. J Agric Food Chem 2010, 58:10085-10091.
59. Paschke A. Aspects of food processing and its effect on allergen structure. Mol Nutr Food Res 2009, 53:959-962.
60. Matthes A., Schmitz-Eiberger M. Apple (Malus domestica L. Borkh.) allergen Mal d 1: effect of cultivar, cultivation system, and storage conditions. J Agric Food Chem 2009, 57:10548-10553.
61. Sancho A.I., Foxall R., Rigby N.M., Browne T., Zuidmeer L., van Ree R., et al. Maturity and storage influence on the apple (Malus domestica) allergen Mal d 3, a nonspecific lipid transfer protein. J Agric Food Chem 2006, 54:5098-5104.
62. Ciardiello M.A., Giangrieco I., Tuppo L., Tamburrini M., Buccheri M., Palazzo P., et al. Influence of the natural ripening stage, cold storage, and ethylene treatment on the protein and IgE-binding profiles of green and gold kiwi fruit extracts. J Agric Food Chem 2009, 57:1565-1571.
63. Brenna O.V., Pastorello E.A., Farioli L., Pravettoni V., Pompei C. Presence of allergenic proteins in different peach (Prunus persica) cultivars and dependence of their content on fruit ripening. J Agric Food Chem 2004, 52:7997-8000.
64. Pedreschi R., Hertog M., Robben J., Lilley K.S., Karp N.A., Baggerman G., et al. Gel-based proteomics approach to the study of metabolic changes in pear tissue during storage. J Agric Food Chem 2009, 57:6997-7004.
65. Schmidt H., Gelhaus C., Latendorf T., Nebendahl M., Petersen A., Krause S., et al. 2-D DIGE analysis of the proteome of extracts from peanut variants reveals striking differences in major allergen contents. Proteomics 2009, 9:3507-3521.
66. Schmidt H., Gelhaus C., Nebendahl M., Janssen O., Petersen A. Characterization of Phleum pratense pollen extracts by 2-D DIGE and allergen immunoreactivity. Proteomics 2010, 10:4352-4362.
67. Guarino C., Arena S., De Simone L., D'Ambrosio C., Santoro S., Rocco M., et al. Proteomic analysis of the major soluble components in Annurca apple flesh. Mol Nutr Food Res 2007, 51:255-262.
68. Teshima R., Nakamura R., Satoh R., Nakamura R. 2D-DIGE analysis of rice proteins from different cultivars. Regul Toxicol Pharmacol 2010, 58:S30-S35.
69. Erler A., Hawranek T., Krückemeier L., Asam C., Egger M., Ferreira F., et al. Proteomic profiling of birch (Betula verrucosa) pollen extracts from different origins. Proteomics 2011, 11:1486-1498.
70. Liang X.Q., Luo M., Holbrook C.C., Guo B.Z. Storage protein profiles in Spanish and runner market type peanuts and potential markers. BMC Plant Biol 2006, 6:24.
71. Napoli A., Aiello D., Di Donna L., Moschidis P., Sindona G. Vegetable proteomics: the detection of Ole e 1 isoallergens by peptide matching of MALDI MS/MS spectra of underivatized and dansylated glycopeptides. J Proteome Res 2008, 7:2723-2732.
72. Fujimura T., Shigeta S., Kawamoto S., Aki T., Masubuchi M., Hayashi T., et al. Two-dimensional IgE-binding spectrum of Japanese cedar (Cryptomeria japonica) pollen allergens. Int Arch Allergy Immunol 2004, 133:125-135.
73. Zhang C., Ding Z., Xu X., Wang Q., Qin G., Tian S. Crucial roles of membrane stability and its related proteins in the tolerance of peach fruit to chilling injury. Amino Acids 2010, 39:181-194.
74. Šauliene I., Veriankaite L. Analysis of high allergenicity airborne pollen dispersion: common ragweed study case in Lithuania. Ann Agric Environ Med 2012, 19:415-419.
75. Codex Alimentarius Commission Alinorm 03/34: Joint FAO/WHO food Standard Programme, Codex Alimentarius Commission, Twenty-Fifth Session, Rome, 30 June-5 July, 2003. Appendix III, Guideline for the conduct of food safety assessment of foods derived from recombinant-DNA plants and Appendix IV, Annex on the assessment of possible allergenicity 2003, 47-60.
76. Batista R., Martins I., Jeno P., Ricardo C.P., Oliveira M.M. A proteomic study to identify soya allergens-the human response to transgenic versus non-transgenic soya samples. Int Arch Allergy Immunol 2007, 144:29-38.
77. Emami K., Morris N.J., Cockell S.J., Golebiowska G., Shu Q.Y., Gatehouse A.M. Changes in protein expression profiles between a low phytic acid rice (Oryza sativa L. ssp. japonica) line and its parental line: a proteomic and bioinformatic approach. J Agric Food Chem 2010, 58:6912-6922.
78. Nakamura R., Satoh R., Nakamura R., Shimazaki T., Kasuga M., Yamaguchi-Shinozaki K., et al. Immunoproteomic and two-dimensional difference gel electrophoresis analysis of Arabidopsis dehydration response element-binding protein 1A (DREB1A)-transgenic potato. Biol Pharm Bull 2010, 33(8):1418-1425.
79. Fonseca C., Planchon S., Renaut J., Oliveira M.M., Batista R. Characterization of maize allergens - MON810 vs. its non-transgenic counterpart. J Proteomics 2012, 75:2027-2037.
80. Stevenson S.E., Houston N.L., Thelen J.J. Evolution of seed allergen quantification-from antibodies to mass spectrometry. Regul Toxicol Pharmacol 2010, 58:S36-S41.
81. Stevenson S.E., Chu Y., Ozias-Akins P., Thelen J.J. Validation of gel-free, label-free quantitative proteomics approaches: applications for seed allergen profiling. J Proteomics 2009, 72:555-566.
82. Ren Y., Lv J., Wang H., Li L., Peng Y., Qu L.J. A comparative proteomics approach to detect unintended effects in transgenic Arabidopsis. J Genet Genomics 2009, 36:629-639.
83. Gong C.Y., Li Q., Yu H.T., Wang Z., Wang T. Proteomics insight into the biological safety of transgenic modification of rice as compared with conventional genetic breeding and spontaneous genotypic variation. Proteome Res 2012, 11(5):3019-3029.
84. Thelen J.J. Proteomics tools and resources for investigating protein allergens in oilseeds. Regul Toxicol Pharmacol 2009, 54:S41-S45.
85. Natarajan S.S. Natural variability in abundance of prevalent soybean proteins. Regul Toxicol Pharmacol 2010, 58:S26-S29.
86. Natarajan S., Xu C., Caperna T.J., Garrett W.M. Comparison of protein solubilization methods suitable for proteomic analysis of soybean seed proteins. Anal Biochem 2005, 342:214-220.
87. Beyer K., Bardina L., Grishina G., Sampson H.A. Identification of sesame seed allergens by 2-dimensional proteomics and Edman sequencing: seed storage proteins as common food allergens. J Allergy Clin Immunol 2002, 110:154-159.
88. Wagner S., Bublin M., Hafner C., Kopp T., Allwardt D., Seifert U., et al. Generation of allergen-enriched protein fractions of Hevea brasiliensis latex for in vitro and in vivo diagnosis. Int Arch Allergy Immunol 2007, 143:246-254.
89. Le L.Q., Lorenz Y., Scheurer S., Fötisch K., Enrique E., Bartra J., et al. Design of tomato fruits with reduced allergenicity by dsRNAi-mediated inhibition of ns-LTP (Lyc e 3) expression. Plant Biotechnol J 2006, 4:231-242.
90. Bässler O.Y., Weiss J., Wienkoop S., Lehmann K., Scheler C., Dölle S., et al. Evidence for novel tomato seed allergens: IgE-reactive legumin and vicilin proteins identified by multidimensional protein fractionation-mass spectrometry and in silico epitope modeling. J Proteome Res 2009, 8:1111-1122.
91. Fasoli E., Pastorello E.A., Farioli L., Scibilia J., Aldini G., Carini M., et al. Searching for allergens in maize kernels via proteomic tools. J Proteomics 2009, 72:501-510.