-
1
-
-
0032830639
-
Rett syndrome is caused by mutations in X-linked MeCP2 encoding methyl-CpG-binding protein 2
-
Amir, R. E., Van den Veyer, I. B., Wan, M., Tran, C. Q., Francke, U., Zoghbi, H. Y. (1999) Rett syndrome is caused by mutations in X-linked MeCP2 encoding methyl-CpG-binding protein 2. Nat Genet 23:185-188.
-
(1999)
Nat Genet
, vol.23
, pp. 185-188
-
-
Amir, R.E.1
Van Den Veyer, I.B.2
Wan, M.3
Tran, C.Q.4
Francke, U.5
Zoghbi, H.Y.6
-
2
-
-
0027141519
-
Number of CpG islands and genes in human and mouse
-
Antequera, F., Bird, A. (1993) Number of CpG islands and genes in human and mouse. Proc Natl Acad Sci USA 90:1195-1199.
-
(1993)
Proc Natl Acad Sci USA
, vol.90
, pp. 1195-1199
-
-
Antequera, F.1
Bird, A.2
-
3
-
-
0027981255
-
Predicting the total number of human genes
-
Antequera, F., Bird, A. (1994) Predicting the total number of human genes. Nat Genet 8:114.
-
(1994)
Nat Genet
, vol.8
, pp. 114
-
-
Antequera, F.1
Bird, A.2
-
4
-
-
0042329754
-
Structure, function and evolution of CpG island promoters
-
Antequera, F. (2003) Structure, function and evolution of CpG island promoters. Cellular and Molecular Life Sciences 60(8):1647-1658.
-
(2003)
Cellular and Molecular Life Sciences
, vol.60
, Issue.8
, pp. 1647-1658
-
-
Antequera, F.1
-
5
-
-
53649097070
-
recognition of hemi-methylated DNA by the SRA protein UHFR1 by a base-flipping mechanism
-
Arita, K., Ariyoshi, M., Tochio, H., Nakamura, Y., Shirakawa, M. (2008) recognition of hemi-methylated DNA by the SRA protein UHFR1 by a base-flipping mechanism. Nature 455:818-822.
-
(2008)
Nature
, vol.455
, pp. 818-822
-
-
Arita, K.1
Ariyoshi, M.2
Tochio, H.3
Nakamura, Y.4
Shirakawa, M.5
-
6
-
-
0037059080
-
RNA directed DNA methylation in Arabidopsis
-
Aufstatz, W., Mette, M. F., Van der Winden, J., Matzke, A. M., Matzke, M. (2002) RNA directed DNA methylation in Arabidopsis. Proc Natl Acad Sci USA 99:16499-16506.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 16499-16506
-
-
Aufstatz, W.1
Mette, M.F.2
van der Winden, J.3
Matzke, A.M.4
Matzke, M.5
-
7
-
-
0035228079
-
X-chromosome inactivation:counting, choice and initiation
-
Avner, P., Heard, E. (2001) X-chromosome inactivation:counting, choice and initiation. Nat Rev Genet 2:59-67.
-
(2001)
Nat Rev Genet
, vol.2
, pp. 59-67
-
-
Avner, P.1
Heard, E.2
-
8
-
-
33646831821
-
Telomeres, chromosome instability and cancer
-
Bailey, S. M., Murnane, J. P. (2006) Telomeres, chromosome instability and cancer. Nucl Acids Res 34(8):2408-2417.
-
(2006)
Nucl Acids Res
, vol.34
, Issue.8
, pp. 2408-2417
-
-
Bailey, S.M.1
Murnane, J.P.2
-
9
-
-
67649160614
-
Epigenetics:connecting environment and genotype to phenotype and disease
-
Barros, S. P., Offenbacher, S. (2009) Epigenetics:connecting environment and genotype to phenotype and disease. J Dent Res 88:400-408.
-
(2009)
J Dent Res
, vol.88
, pp. 400-408
-
-
Barros, S.P.1
Offenbacher, S.2
-
10
-
-
33644846509
-
Epigenetic gene silencing in cancer:a mechanism for early oncogenic pathway addiction?
-
Baylin, S. B., Ohm, J. E. (2006) Epigenetic gene silencing in cancer:a mechanism for early oncogenic pathway addiction? Nat rev Cancer 6:107-116.
-
(2006)
Nat rev Cancer
, vol.6
, pp. 107-116
-
-
Baylin, S.B.1
Ohm, J.E.2
-
11
-
-
0034744639
-
Aberrant patterns of DNA methylation, chromatin formation and gene expression in cancer
-
Baylin, S. B., Esteller, M., Rountree M. R., Bachman, K. E., Schuebel, K., Herman, J. G. (2001) Aberrant patterns of DNA methylation, chromatin formation and gene expression in cancer. Hum Mol Genet 10:687-692.
-
(2001)
Hum Mol Genet
, vol.10
, pp. 687-692
-
-
Baylin, S.B.1
Esteller, M.2
Rountree, M.R.3
Bachman, K.E.4
Schuebel, K.5
Herman, J.G.6
-
12
-
-
0032126345
-
Cytosine methylation of repeated sequences in eukaryotes:the role of DNA pairing
-
Bender, J. (1998) Cytosine methylation of repeated sequences in eukaryotes:the role of DNA pairing. Trends Biochem Sci 23(7):252-256.
-
(1998)
Trends Biochem Sci
, vol.23
, Issue.7
, pp. 252-256
-
-
Bender, J.1
-
13
-
-
33847032960
-
The mammalian epigenome
-
Bernstein, B. E., Meissner, A., Lander, E. S. (2007) The mammalian epigenome. Cell 128(4):669-681.
-
(2007)
Cell
, vol.128
, Issue.4
, pp. 669-681
-
-
Bernstein, B.E.1
Meissner, A.2
Lander, E.S.3
-
14
-
-
0033753779
-
The DNA methyltransferases of mammals
-
Bestor, T. H. (2000) The DNA methyltransferases of mammals. Hum Mol Genet 9(16):2395-2402.
-
(2000)
Hum Mol Genet
, vol.9
, Issue.16
, pp. 2395-2402
-
-
Bestor, T.H.1
-
15
-
-
0021086610
-
Two DNA methyltransferases from mourine erythroleukemia cells:purification, sequencing, specificity and mode of interaction with DNA
-
Bestor, T. H., Ingram, V. M. (1983) Two DNA methyltransferases from mourine erythroleukemia cells:purification, sequencing, specificity and mode of interaction with DNA. Proc Natl Acad Sci USA 80:5559-5563.
-
(1983)
Proc Natl Acad Sci USA
, vol.80
, pp. 5559-5563
-
-
Bestor, T.H.1
Ingram, V.M.2
-
17
-
-
0030115772
-
Creation of genomic methylation patterns
-
Bestor, T. H., Tycko, B. (1996) Creation of genomic methylation patterns. Nat Genet 12:363-367.
-
(1996)
Nat Genet
, vol.12
, pp. 363-367
-
-
Bestor, T.H.1
Tycko, B.2
-
18
-
-
0023701018
-
Cloning and sequencing of a cDNA encoding DNA methyltransferase of mouse cells
-
Bestor, T., Laudano, A., Mattaliano, R., Ingram, V. (1988) Cloning and sequencing of a cDNA encoding DNA methyltransferase of mouse cells. J Mol Biol 203:971.
-
(1988)
J Mol Biol
, vol.203
, pp. 971
-
-
Bestor, T.1
Laudano, A.2
Mattaliano, R.3
Ingram, V.4
-
19
-
-
44049120882
-
CpG islands in mammalian gene promoters are inheritently resistant to de novo methylation
-
Bestor, T. H., Gundersen, G., Kolsto, A. B., Prydz, H. (1992) CpG islands in mammalian gene promoters are inheritently resistant to de novo methylation. Genet Anal Tech Appl 9:48-53.
-
(1992)
Genet Anal Tech Appl
, vol.9
, pp. 48-53
-
-
Bestor, T.H.1
Gundersen, G.2
Kolsto, A.B.3
Prydz, H.4
-
20
-
-
0033580326
-
A mammalian protein with specific demethylase activity for mCpG DNA
-
Bhattacharaya, S. K., Ramchandani, S., Cervoni, N., Szyf, M. (1999) A mammalian protein with specific demethylase activity for mCpG DNA. Nature 397:579-583.
-
(1999)
Nature
, vol.397
, pp. 579-583
-
-
Bhattacharaya, S.K.1
Ramchandani, S.2
Cervoni, N.3
Szyf, M.4
-
21
-
-
84886193348
-
Unmasking a killer:DNA O-methylguanine and the cytotoxicity of methylationg agents
-
Bignani, M., O'Driscoll, M., Aquilina, G., Karran, P. (2005) Unmasking a killer:DNA O-methylguanine and the cytotoxicity of methylationg agents. Mutat Res 462(2-3):71-82.
-
(2005)
Mutat Res
, vol.462
, Issue.2-3
, pp. 71-82
-
-
Bignani, M.1
O'Driscoll, M.2
Aquilina, G.3
Karran, P.4
-
23
-
-
0022540321
-
CpG rich islands and the function of DNA methylation
-
Bird, A. P. (1986) CpG rich islands and the function of DNA methylation. Nature 321:209-213.
-
(1986)
Nature
, vol.321
, pp. 209-213
-
-
Bird, A.P.1
-
24
-
-
0028940587
-
Gene number, noise reduction, and biological complexity
-
Bird, A. P. (1995) Gene number, noise reduction, and biological complexity. Trends Genet 11:94.
-
(1995)
Trends Genet
, vol.11
, pp. 94
-
-
Bird, A.P.1
-
25
-
-
0035824504
-
Methylation talk between histones and DNA
-
Bird, A. (2001) Methylation talk between histones and DNA. Science 294(5549):2113-2115.
-
(2001)
Science
, vol.294
, Issue.5549
, pp. 2113-2115
-
-
Bird, A.1
-
26
-
-
0036144048
-
DNA methylation pattern and epigenetic memory
-
Bird, A. (2002) DNA methylation pattern and epigenetic memory. Genes Dev 16:6-21.
-
(2002)
Genes Dev
, vol.16
, pp. 6-21
-
-
Bird, A.1
-
29
-
-
0035929353
-
Switching and signaling at the telomere
-
Blackburn, E. H. (2001) Switching and signaling at the telomere. Cell 106(6):661-673.
-
(2001)
Cell
, vol.106
, Issue.6
, pp. 661-673
-
-
Blackburn, E.H.1
-
30
-
-
0025975985
-
DNA methylation inhibits transcription indirectly via a methyl-CpG-binding protein
-
Boyes, J., Bird, A. (1991) DNA methylation inhibits transcription indirectly via a methyl-CpG-binding protein. Cell 64:1123-1134.
-
(1991)
Cell
, vol.64
, pp. 1123-1134
-
-
Boyes, J.1
Bird, A.2
-
31
-
-
0028104109
-
Sp1 element protect CpG island from de novo methylation
-
Brandeis, M., Frank, D., Kechet, I., Siegfried, Z., Mendelsohn, M., Nemes, A., Temer, V., Razin, A., Cedar, H. (1994) Sp1 element protect CpG island from de novo methylation. Nature 371:435-438.
-
(1994)
Nature
, vol.371
, pp. 435-438
-
-
Brandeis, M.1
Frank, D.2
Kechet, I.3
Siegfried, Z.4
Mendelsohn, M.5
Nemes, A.6
Temer, V.7
Razin, A.8
Cedar, H.9
-
32
-
-
0032714089
-
Densely methylated sequences that are preferentially localized at telomere proximal regions of human chromosomes
-
Brock, G. J., Charlton, J., Bird, A. (1999) Densely methylated sequences that are preferentially localized at telomere proximal regions of human chromosomes. Gene 240(2):269-277.
-
(1999)
Gene
, vol.240
, Issue.2
, pp. 269-277
-
-
Brock, G.J.1
Charlton, J.2
Bird, A.3
-
33
-
-
33847250332
-
DNMT1 knockout delivers a strong blow to genome stability and cell viability
-
Brown, K. D., Robertson, K. D. (2007) DNMT1 knockout delivers a strong blow to genome stability and cell viability. Nat Genet 39(3):289-290.
-
(2007)
Nat Genet
, vol.39
, Issue.3
, pp. 289-290
-
-
Brown, K.D.1
Robertson, K.D.2
-
34
-
-
18444361838
-
DNA methylation and chromatin structure:the puzzling CpG islands
-
Caiafa, P., Zampieri, M. (2005) DNA methylation and chromatin structure:the puzzling CpG islands. J Cell Biochem 94:257-265.
-
(2005)
J Cell Biochem
, vol.94
, pp. 257-265
-
-
Caiafa, P.1
Zampieri, M.2
-
35
-
-
68149100569
-
The role of epigenetics in aging and age-related diseases
-
Calvanese, V., Lara, E., Kahn, A., Fraga, M. F. (2009) The role of epigenetics in aging and age-related diseases. Aging Res Rev 8:268-276.
-
(2009)
Aging Res Rev
, vol.8
, pp. 268-276
-
-
Calvanese, V.1
Lara, E.2
Kahn, A.3
Fraga, M.F.4
-
36
-
-
0022309434
-
The role of S-adenosylhomocysteine in the biological utilization of S-adenosymethionine
-
In:G. Cantoni and A. Razin (eds), Alan R. Liss, Inc., New York
-
Cantoni, G. (1985) The role of S-adenosylhomocysteine in the biological utilization of S-adenosymethionine. In:G. Cantoni and A. Razin (eds), Biochemistry and Biology of DNA Methylation. Alan R. Liss, Inc., New York, pp. 47-65.
-
(1985)
Biochemistry and Biology of DNA Methylation
, pp. 47-65
-
-
Cantoni, G.1
-
38
-
-
67349190247
-
Linking DNA methylation and histone modification:patterns and paradigms
-
Cedar, H., Bergman, Y. (2009) Linking DNA methylation and histone modification:patterns and paradigms. Nat Rev Genet 10(5):295-304.
-
(2009)
Nat Rev Genet
, vol.10
, Issue.5
, pp. 295-304
-
-
Cedar, H.1
Bergman, Y.2
-
39
-
-
0034780410
-
Reduced rates of gene loss, gene silencing and gene mutations in Dnmt1-deficient embryonic stem cells
-
Chan, M. F., van Amerongen, R., Nijjar, T., Cupper, E., Jones, P. A., Laird, P. W. (2001) Reduced rates of gene loss, gene silencing and gene mutations in Dnmt1-deficient embryonic stem cells. Moll Cell Biol 21(22):7587-7600.
-
(2001)
Moll Cell Biol
, vol.21
, Issue.22
, pp. 7587-7600
-
-
Chan, M.F.1
Van Amerongen, R.2
Nijjar, T.3
Cupper, E.4
Jones, P.A.5
Laird, P.W.6
-
40
-
-
0009922867
-
The composition of the desoxypentose nucleic acids of thymus and spleen
-
Chargaff, E., Vischer, E., Doniger, R., Green, C., Misani, F. (1949) The composition of the desoxypentose nucleic acids of thymus and spleen. J Biol Chem 177:405-416.
-
(1949)
J Biol Chem
, vol.177
, pp. 405-416
-
-
Chargaff, E.1
Vischer, E.2
Doniger, R.3
Green, C.4
Misani, F.5
-
41
-
-
0028946713
-
DNA modification by methyltransferases
-
Cheng, X. (1995) DNA modification by methyltransferases. Curr Opin Struct Biol 5(1):4-10.
-
(1995)
Curr Opin Struct Biol
, vol.5
, Issue.1
, pp. 4-10
-
-
Cheng, X.1
-
42
-
-
0035883736
-
AdoMet-dependent methylation, DNA methyltransferases and base flipping
-
Cheng, X., Roberts, R. J. (2001) AdoMet-dependent methylation, DNA methyltransferases and base flipping. Nucl Acids Res 29(18):3784-3795.
-
(2001)
Nucl Acids Res
, vol.29
, Issue.18
, pp. 3784-3795
-
-
Cheng, X.1
Roberts, R.J.2
-
43
-
-
0026316928
-
Direct identification of the active site nucleophile in a DNA (cytosine-5)-methyltransferase
-
Chen, L., Macmillan, A. M., Chang, W., Ezaz-Nikpay, K., Lane, W. S., Verdine, G. L. (1991) Direct identification of the active site nucleophile in a DNA (cytosine-5)-methyltransferase. Biochemistry 30:11018-11025.
-
(1991)
Biochemistry
, vol.30
, pp. 11018-11025
-
-
Chen, L.1
Macmillan, A.M.2
Chang, W.3
Ezaz-Nikpay, K.4
Lane, W.S.5
Verdine, G.L.6
-
44
-
-
0027338134
-
Crystal structure of the HhaI DNA methyltransferase complexed with S-adenosyl-L-methionine
-
Cheng, X., Kumar, S., Posfai, P, Pflugrath, J., Roberts, R. (1993) Crystal structure of the HhaI DNA methyltransferase complexed with S-adenosyl-L-methionine. Cell 74:299-310.
-
(1993)
Cell
, vol.74
, pp. 299-310
-
-
Cheng, X.1
Kumar, S.2
Posfai, P.3
Pflugrath, J.4
Roberts, R.5
-
45
-
-
0030770835
-
Human DNA (cytosine-5) methyltransferase-PCNA complex as a target for p21WAF1
-
Chuang, L. S., Ian, H. I., Koh, T. W., Ng, H. H., Xu, G., Li, B. F. (1997) Human DNA (cytosine-5) methyltransferase-PCNA complex as a target for p21WAF1. Science 277:1996-2000.
-
(1997)
Science
, vol.277
, pp. 1996-2000
-
-
Chuang, L.S.1
Ian, H.I.2
Koh, T.W.3
Ng, H.H.4
Xu, G.5
Li, B.F.6
-
46
-
-
0018185292
-
Molecular basis of base substitution hotspots in
-
Colondre, C., Miller, J. H., Farabaugh, P. J., Gilbert, W. (1978) Molecular basis of base substitution hotspots in . Nature 274:775-780.
-
(1978)
Nature
, vol.274
, pp. 775-780
-
-
Colondre, C.1
Miller, J.H.2
Farabaugh, P.J.3
Gilbert, W.4
-
47
-
-
0035031279
-
Methylation matters
-
Costello, F., Plass, C. (2001) Methylation matters. J Med Genet 38:285-303.
-
(2001)
J Med Genet
, vol.38
, pp. 285-303
-
-
Costello, F.1
Plass, C.2
-
49
-
-
0028340280
-
Purification of CpG islands using a methylated DNA binding column
-
Cross, S. H., Charlton, J. A., Nan, X., Bird, A. P. (1994) Purification of CpG islands using a methylated DNA binding column. Nat Genet 6:236-244.
-
(1994)
Nat Genet
, vol.6
, pp. 236-244
-
-
Cross, S.H.1
Charlton, J.A.2
Nan, X.3
Bird, A.P.4
-
50
-
-
33750688857
-
Epigenetic t̂ete-a-t̂ete:the bilateral relationship between chromatin modifications and DNA methylation
-
D'Alessio, A. C., Szyf, M. (2006) Epigenetic t̂ete-a-t̂ete:the bilateral relationship between chromatin modifications and DNA methylation. Biochem Cell Biol 84(4):463-476.
-
(2006)
Biochem Cell Biol
, vol.84
, Issue.4
, pp. 463-476
-
-
D'Alessio, A.C.1
Szyf, M.2
-
51
-
-
35649018164
-
Acetylation-induced transcription is required for active DNA demethylation in methylation-silenced genes
-
D'Alessio, A. C., Weaver, I. C. G., Szyf, M. (2007) Acetylation-induced transcription is required for active DNA demethylation in methylation-silenced genes.Mol Cell Biol 27(21):7462-7474.
-
(2007)
Mol Cell Biol
, vol.27
, Issue.21
, pp. 7462-7474
-
-
D'Alessio, A.C.1
Weaver, I.C.G.2
Szyf, M.3
-
52
-
-
21544446158
-
On the biological significance of DNA methylation
-
Doerfler, W. (2005) On the biological significance of DNA methylation. Biochemistry (Moskow) 70:505-524.
-
(2005)
Biochemistry (Moskow)
, vol.70
, pp. 505-524
-
-
Doerfler, W.1
-
53
-
-
33645958291
-
De novo methylation, long-term promoter silencing, methylation patterns in the human genome and consequences of foreign DNA insertion
-
In:W. Doerfler and P. Bohm (eds), Springer, Berlin Heidelberg
-
Doerfler, W. (2006) De novo methylation, long-term promoter silencing, methylation patterns in the human genome and consequences of foreign DNA insertion. In:W. Doerfler and P. Bohm (eds), DNA Methylation Basic Mechanisms. Springer, Berlin Heidelberg, pp. 125-175.
-
(2006)
DNA Methylation Basic Mechanisms
, pp. 125-175
-
-
Doerfler, W.1
-
54
-
-
0019198357
-
Mutagenic deamination of cytidine residues in DNA
-
Duncan, B. K., Miller, J. H. (1980) Mutagenic deamination of cytidine residues in DNA. Nature 287:560-561.
-
(1980)
Nature
, vol.287
, pp. 560-561
-
-
Duncan, B.K.1
Miller, J.H.2
-
55
-
-
12144255958
-
Replication-independent chromatin loading of Dnmt1 during G2 and M phases
-
Easwaran, HP, Schermeleck, L., Leonardt, H., Cardoso, M. C. (2004) Replication-independent chromatin loading of Dnmt1 during G2 and M phases. EMBO Rep 5(12):1181-1186.
-
(2004)
EMBO Rep
, vol.5
, Issue.12
, pp. 1181-1186
-
-
Easwaran, H.P.1
Schermeleck, L.2
Leonardt, H.3
Cardoso, M.C.4
-
56
-
-
2642531973
-
Epigenetics in human disease and prospects for epigenetic therapy
-
Egger, G., Liang, G., Aparicio, A., Jones, P. A. (2004) Epigenetics in human disease and prospects for epigenetic therapy. Nature 429:457-463.
-
(2004)
Nature
, vol.429
, pp. 457-463
-
-
Egger, G.1
Liang, G.2
Aparicio, A.3
Jones, P.A.4
-
57
-
-
33748998743
-
Identification of DNMT1 (DNA methyltransferase 1) hypomorphs in somatic knockouts suggests an essential role for DNMT1 in cell survival
-
Egger, G., Jeong, S., Escobar, S. G., Cortez, C. C., Li, T. N. H., Saito, Y., Yoo, C. B., Jones, P. A., Liang, G. (2006) Identification of DNMT1 (DNA methyltransferase 1) hypomorphs in somatic knockouts suggests an essential role for DNMT1 in cell survival. Proc Natl Acad Sci USA 103(38):14080-14085.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, Issue.38
, pp. 14080-14085
-
-
Egger, G.1
Jeong, S.2
Escobar, S.G.3
Cortez, C.C.4
Li, T.N.H.5
Saito, Y.6
Yoo, C.B.7
Jones, P.A.8
Liang, G.9
-
58
-
-
0020489781
-
Amount and distribution of 5-methylcytosine in human DNA from different types of tissues or cells
-
Ehrlich, M. (1982) Amount and distribution of 5-methylcytosine in human DNA from different types of tissues or cells. Nucl Acids Res 10:2709-2721.
-
(1982)
Nucl Acids Res
, vol.10
, pp. 2709-2721
-
-
Ehrlich, M.1
-
59
-
-
0036324032
-
DNA hypomethylation, cancer, the immunodeficiency, centromeric region instability, facial anomalies syndrome and chromosomal rearrangements
-
Ehrlich, M. (2002) DNA hypomethylation, cancer, the immunodeficiency, centromeric region instability, facial anomalies syndrome and chromosomal rearrangements. J Nutr 132:2424S-2429S.
-
(2002)
J Nutr
, vol.132
-
-
Ehrlich, M.1
-
60
-
-
0142216231
-
The ICF syndrome, a DNA methyltransferase 3B deficiency and immunodeficiency disease
-
Ehrlich, M. (2003) The ICF syndrome, a DNA methyltransferase 3B deficiency and immunodeficiency disease. Clin Immunol 109:17-28.
-
(2003)
Clin Immunol
, vol.109
, pp. 17-28
-
-
Ehrlich, M.1
-
61
-
-
65449186589
-
A systemic search for DNA methyltransferase polymorphisms reveals a rare DNMT3L variant associated with subtelomeric hypomethylation
-
El-Maarri, O., Kareta, M. S., Mikeska, T., Becker, T., Diaz-Laava, A., Junen, J., Nusgen, N., Behne, F., Wienker, T., Waha, A., Oldenburg, J., Chedin, F. (2009) A systemic search for DNA methyltransferase polymorphisms reveals a rare DNMT3L variant associated with subtelomeric hypomethylation. Hum Mol Genet 18:1755-1768.
-
(2009)
Hum Mol Genet
, vol.18
, pp. 1755-1768
-
-
El-Maarri, O.1
Kareta, M.S.2
Mikeska, T.3
Becker, T.4
Diaz-Laava, A.5
Junen, J.6
Nusgen, N.7
Behne, F.8
Wienker, T.9
Waha, A.10
Oldenburg, J.11
Chedin, F.12
-
62
-
-
0027881738
-
Enzymatic DNA methylation through a locally impaired intermediate
-
Erlanson, D., Dhen, L., Verdine, G. L. (1993) Enzymatic DNA methylation through a locally impaired intermediate. J Am Chem Soc 115:12583-12584.
-
(1993)
J Am Chem Soc
, vol.115
, pp. 12583-12584
-
-
Erlanson, D.1
Dhen, L.2
Verdine, G.L.3
-
63
-
-
13844320649
-
Aberrant DNA methylation as a cancer-inducing mechanism
-
Esteller, M. (2005) Aberrant DNA methylation as a cancer-inducing mechanism. Annu Rev Pharmacol Toxicol 45:629-656.
-
(2005)
Annu Rev Pharmacol Toxicol
, vol.45
, pp. 629-656
-
-
Esteller, M.1
-
64
-
-
33947315736
-
Cancer epigenomics:DNA methylomes and histone-modification maps
-
Esteller, M. (2007) Cancer epigenomics:DNA methylomes and histone-modification maps. Nat Rev Genet 8(4):286-298.
-
(2007)
Nat Rev Genet
, vol.8
, Issue.4
, pp. 286-298
-
-
Esteller, M.1
-
65
-
-
40849139208
-
Epigenetics in cancer
-
Esteller, M. (2008) Epigenetics in cancer. N Engl J Med 358(11):1148-1159.
-
(2008)
N Engl J Med
, vol.358
, Issue.11
, pp. 1148-1159
-
-
Esteller, M.1
-
67
-
-
0035870248
-
A gene hypermethylation profile of human cancer
-
Esteller, M., Corn, P. G., Baylin, S. B., Herman, J. G. (2001a) A gene hypermethylation profile of human cancer. Cancer Res 8:3225-3229.
-
(2001)
Cancer Res
, vol.8
, pp. 3225-3229
-
-
Esteller, M.1
Corn, P.G.2
Baylin, S.B.3
Herman, J.G.4
-
68
-
-
18244388241
-
DNA methylation patterns in hereditary human cancers mimic sporadic tumorigenesis
-
Esteller, M., Fraga, M. F., Guo, M., Garcia-Foncillas, J., Hedenfalk, I., Godwin, A. K., Trojan, J., Vaurs-Barrière, C., Bignon, Y.-J., Ramus, S., Benitez, J., Caldes, T., Akiyama, Y., Yuasa, Y., Launonen, V., Canal, M. J., Rodriguez, R., Capella, G., Peinado, M. A., Borg, A., Aaltonen, L. A., Ponder, B. A., Baylin, S. B., Herman, J. G. (2001b) DNA methylation patterns in hereditary human cancers mimic sporadic tumorigenesis. Hum Mol Genet 10(26):3001-3007.
-
(2001)
Hum Mol Genet
, vol.10
, pp. 3001-3007
-
-
Esteller, M.1
Fraga, M.F.2
Guo, M.3
Garcia-Foncillas, J.4
Hedenfalk, I.5
Godwin, A.K.6
Trojan, J.7
Vaurs-Barrière, C.8
Bignon, Y.-J.9
Ramus, S.10
Benitez, J.11
Caldes, T.12
Akiyama, Y.13
Yuasa, Y.14
Launonen, V.15
Canal, M.J.16
Rodriguez, R.17
Capella, G.18
Peinado, M.A.19
Borg, A.20
Aaltonen, L.A.21
Ponder, B.A.22
Baylin, S.B.23
Herman, J.G.24
more..
-
69
-
-
18544364773
-
Cancer epigenetics and methylation
-
Esteller, M., Fraga, M. F., Paz, M. F., Campo, E., Colomer, D., Novo, F. J., Calasanz, M. J., Galm, O., Guo, M., Menitez, J., Herman, J. G. (2002) Cancer epigenetics and methylation. Science 297(5588):1807-1808.
-
(2002)
Science
, vol.297
, Issue.5588
, pp. 1807-1808
-
-
Esteller, M.1
Fraga, M.F.2
Paz, M.F.3
Campo, E.4
Colomer, D.5
Novo, F.J.6
Calasanz, M.J.7
Galm, O.8
Guo, M.9
Menitez, J.10
Herman, J.G.11
-
70
-
-
33751209468
-
Direct interaction between DNMT1 and G9a coordinates DNA and histone methylation during replication
-
Estève, P.-O., Chin, H. G., Smallwood, A., Feehery, G. R., Gangisetty, O., Karpf, A. R., Carey, M. F., Pradhan, S. (2006) Direct interaction between DNMT1 and G9a coordinates DNA and histone methylation during replication. Genes Dev 20:3089-3103.
-
(2006)
Genes Dev
, vol.20
, pp. 3089-3103
-
-
Estève, P.-O.1
Chin, H.G.2
Smallwood, A.3
Feehery, G.R.4
Gangisetty, O.5
Karpf, A.R.6
Carey, M.F.7
Pradhan, S.8
-
71
-
-
0035933336
-
The activity of the murine DNA methyltransferase Dnmt1 is controlled by interaction of the catalytic domain with the N-terminal part of the enzyme leading to an allosteric activation of the enzyme after binding to methylated DNA
-
Fatemi, M., Hermann, A., Pradhan, S., Jeltsch, A. (2001) The activity of the murine DNA methyltransferase Dnmt1 is controlled by interaction of the catalytic domain with the N-terminal part of the enzyme leading to an allosteric activation of the enzyme after binding to methylated DNA. J Mol Biol 309(5):1189-99.
-
(2001)
J Mol Biol
, vol.309
, Issue.5
, pp. 1189-1199
-
-
Fatemi, M.1
Hermann, A.2
Pradhan, S.3
Jeltsch, A.4
-
72
-
-
0002450504
-
Structure and evolution of AdoMet-dependent methyltransferases
-
In:X. Cheng and R. M. Blumethal (eds), World Scientific Publishing, NJ
-
Fauman, E. B., Blumetnthal, R. M., Cheng, X. (1999) Structure and evolution of AdoMet-dependent methyltransferases. In:X. Cheng and R. M. Blumethal (eds), AdoMet-dependent Methyltransferases:Structures and Functions. World Scientific Publishing, NJ, pp. 1-38.
-
(1999)
AdoMet-dependent Methyltransferases:Structures and Functions
, pp. 1-38
-
-
Fauman, E.B.1
Blumetnthal, R.M.2
Cheng, X.3
-
73
-
-
5444255150
-
The epigenetics of cancer etiology
-
Feinberg, A. P. (2004) The epigenetics of cancer etiology. Semin Cancer Biol 14:427-432.
-
(2004)
Semin Cancer Biol
, vol.14
, pp. 427-432
-
-
Feinberg, A.P.1
-
74
-
-
34249275353
-
Phenotypic plasticity and the epigenetics of human disease
-
Feinberg, A. P. (2007) Phenotypic plasticity and the epigenetics of human disease. Nature 447:433-440.
-
(2007)
Nature
, vol.447
, pp. 433-440
-
-
Feinberg, A.P.1
-
75
-
-
1042278765
-
The history of cancer epigenetics
-
Feinberg, A., P., Tycko, B. (2004) The history of cancer epigenetics. Nat Rev Cancer 4:143-153.
-
(2004)
Nat Rev Cancer
, vol.4
, pp. 143-153
-
-
Feinberg, A.P.1
Tycko, B.2
-
76
-
-
70449093724
-
Np95 interacts with de novo DNA methyltransferases Dnmt3a and Dnmt3b and mediates epigenetic silencing
-
Fellinger, K., Meilinger, D., Bultmann, S., Bonapace I. M., Klinkert W. F. F., Spada, F., Leonhardt, H. (2009a) Np95 interacts with de novo DNA methyltransferases Dnmt3a and Dnmt3b and mediates epigenetic silencing. EMBO Rep 10:1259-1264.
-
(2009)
EMBO Rep
, vol.10
, pp. 1259-1264
-
-
Fellinger, K.1
Meilinger, D.2
Bultmann, S.3
Bonapace, I.M.4
Klinkert, W.F.F.5
Spada, F.6
Leonhardt, H.7
-
77
-
-
62649172171
-
Dimerization of DNA methyltransferase 1 is mediated by its regulatory domain
-
Fellinger, K., Rothbauer, U., Felle, M., Längst, G., Leonhardt, H. (2009b) Dimerization of DNA methyltransferase 1 is mediated by its regulatory domain. J Cellular Biochem 106(4):521-528.
-
(2009)
J Cellular Biochem
, vol.106
, Issue.4
, pp. 521-528
-
-
Fellinger, K.1
Rothbauer, U.2
Felle, M.3
Längst, G.4
Leonhardt, H.5
-
78
-
-
63449135035
-
Gene expression divergence in yeast is coupled to evolution of DNA encoded nucleosome organization
-
Field, Y., Fondufe-Mittendorf, Y., Moore, I. K., Mieczkowski, P., Kaplan, N., Lubling, Y., Lieb, J. D., Widom, J., Segal, E. (2009) Gene expression divergence in yeast is coupled to evolution of DNA encoded nucleosome organization. Nat Genet 41:438-445.
-
(2009)
Nat Genet
, vol.41
, pp. 438-445
-
-
Field, Y.1
Fondufe-Mittendorf, Y.2
Moore, I.K.3
Mieczkowski, P.4
Kaplan, N.5
Lubling, Y.6
Lieb, J.D.7
Widom, J.8
Segal, E.9
-
79
-
-
23044514669
-
Epigenetic differences arise during the lifetime of monozygotic twins
-
Fraga, M. F., Ballestar, E., Paz, M. F., Santiago, R., Setien, F., Ballestar, M. L., Heine-Suner, D., Cigudosa, J. C., Urioste, M., Benitez, J., Boix-Chornet, M., Sanchez-Aguilera, A., Charlotte, L., Carlsson, E., Poulsen, P., Vaag, A., Stephan, Z., Spector, T. D., Wu, Y.-Z., Plass, C., Esteller, M. (2005) Epigenetic differences arise during the lifetime of monozygotic twins. Proc Natl Acad Sci USA 102:10604-10609.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 10604-10609
-
-
Fraga, M.F.1
Ballestar, E.2
Paz, M.F.3
Santiago, R.4
Setien, F.5
Ballestar, M.L.6
Heine-Suner, D.7
Cigudosa, J.C.8
Urioste, M.9
Benitez, J.10
Boix-Chornet, M.11
Sanchez-Aguilera, A.12
Charlotte, L.13
Carlsson, E.14
Poulsen, P.15
Vaag, A.16
Stephan, Z.17
Spector, T.D.18
Wu, Y.-Z.19
Plass, C.20
Esteller, M.21
more..
-
80
-
-
0025716284
-
Demethylation of genes in animal cells
-
Frank, D., Lichtenstein, M., Paroush, Z., Bergman, Y., Shani, M., Razin, A., Cedar, H. (1990) Demethylation of genes in animal cells. Philos Trans R Soc Lond B Biol Sci 326:241-251.
-
(1990)
Philos Trans R Soc Lond B Biol Sci
, vol.326
, pp. 241-251
-
-
Frank, D.1
Lichtenstein, M.2
Paroush, Z.3
Bergman, Y.4
Shani, M.5
Razin, A.6
Cedar, H.7
-
81
-
-
39649122136
-
Cancer epigenetics:modifications, screening and therapy
-
Gal-Yam, E. N., Saito, Y., Egger, G., Jones, P. (2008) Cancer epigenetics:modifications, screening and therapy. Annu Rev Med 59:267-280.
-
(2008)
Annu Rev Med
, vol.59
, pp. 267-280
-
-
Gal-Yam, E.N.1
Saito, Y.2
Egger, G.3
Jones, P.4
-
82
-
-
0023216891
-
CpG islands in vertebrate genomes
-
Gardiner-Garden, M., Frommer, M. (1987) CpG islands in vertebrate genomes. J Mol Biol 196:261-282.
-
(1987)
J Mol Biol
, vol.196
, pp. 261-282
-
-
Gardiner-Garden, M.1
Frommer, M.2
-
83
-
-
0242584449
-
Induction of tumors in mice by genomic hypomethylation
-
Gaudet, F., Hodgson, J. G., Eden, A., Jackson-Grusby, L., Dausman, J., Gray, J. W., Leonhards, H., Jaenisch, R. (2003) Induction of tumors in mice by genomic hypomethylation. Science 300:489-492.
-
(2003)
Science
, vol.300
, pp. 489-492
-
-
Gaudet, F.1
Hodgson, J.G.2
Eden, A.3
Jackson-Grusby, L.4
Dausman, J.5
Gray, J.W.6
Leonhards, H.7
Jaenisch, R.8
-
84
-
-
59249109669
-
DNA demethylation by DNA repair
-
Gehring, M., Reik, W., Henikiff, S. (2009) DNA demethylation by DNA repair. Trends Genet 25(2):82-90.
-
(2009)
Trends Genet
, vol.25
, Issue.2
, pp. 82-90
-
-
Gehring, M.1
Reik, W.2
Henikiff, S.3
-
85
-
-
38449115628
-
DNA methylation profile at the DNMT3L promoter:a potential biomarker for cervical cancer
-
Gokul, G., Guatami, B., Malathi, S., Sowjanya, A. P., Poli, U. R., Jain, M., Ramakrishna, G., Khoshla, S. (2007) DNA methylation profile at the DNMT3L promoter:a potential biomarker for cervical cancer. Epigenetics 2(2):80-85.
-
(2007)
Epigenetics
, vol.2
, Issue.2
, pp. 80-85
-
-
Gokul, G.1
Guatami, B.2
Malathi, S.3
Sowjanya, A.P.4
Poli, U.R.5
Jain, M.6
Ramakrishna, G.7
Khoshla, S.8
-
86
-
-
33847047461
-
Epigenetics:a landscape takes shape
-
GEN
-
Goldberg, A. D., Allis, C. D., Bernstein, E. (2007) Epigenetics:a landscape takes shape. Cell 128:635-638. (GEN).
-
(2007)
Cell
, vol.128
, pp. 635-638
-
-
Goldberg, A.D.1
Allis, C.D.2
Bernstein, E.3
-
87
-
-
15744401773
-
Eukaryotic cytosine methyltransferases
-
Goll, M. G., Bestor, T. H. (2005) Eukaryotic cytosine methyltransferases. Annu Rev Biochem 74:481-514.
-
(2005)
Annu Rev Biochem
, vol.74
, pp. 481-514
-
-
Goll, M.G.1
Bestor, T.H.2
-
88
-
-
31144449613
-
Methylation of tRNAAsp by the DNA methyltransferase homolog Dnmt2
-
Goll, M. G., Kirpekar, F., Maggert, K. A., Yoder, J. A., Hsieh, C.-H., Zhang, X., Golic, K. G., Jacobsen, S. E., Bestor, T. H. (2006) Methylation of tRNAAsp by the DNA methyltransferase homolog Dnmt2. Science 311(5759):395-398.
-
(2006)
Science
, vol.311
, Issue.5759
, pp. 395-398
-
-
Goll, M.G.1
Kirpekar, F.2
Maggert, K.A.3
Yoder, J.A.4
Hsieh, C.-H.5
Zhang, X.6
Golic, K.G.7
Jacobsen, S.E.8
Bestor, T.H.9
-
89
-
-
33645702660
-
DNA methyltransferases control telomere length and telomerase recombination in mammalian cells
-
Gonzalo, S., Jaco, I., Fraga, M. H., Chen, T., Li, E., Esteller, M., Blasco, M. A. (2006) DNA methyltransferases control telomere length and telomerase recombination in mammalian cells. Nature Cell Biol 8:416-424.
-
(2006)
Nature Cell Biol
, vol.8
, pp. 416-424
-
-
Gonzalo, S.1
Jaco, I.2
Fraga, M.H.3
Chen, T.4
Li, E.5
Esteller, M.6
Blasco, M.A.7
-
90
-
-
17144369504
-
Mechanism of stimulation of catalytic activity of Dnmt3A and Dnmt3B DNA-(cytosine-C5)-methyltransferases by Dnmt3L
-
Gowher, H., Liebert, K., Hermann, A., Xu, G., Jeltsch, A. (2005) Mechanism of stimulation of catalytic activity of Dnmt3A and Dnmt3B DNA-(cytosine-C5)-methyltransferases by Dnmt3L. J Biol Chem 280:13341-13348.
-
(2005)
J Biol Chem
, vol.280
, pp. 13341-13348
-
-
Gowher, H.1
Liebert, K.2
Hermann, A.3
Xu, G.4
Jeltsch, A.5
-
91
-
-
33644949412
-
Mutational analysis of the catalytic domain of the murine Dnmt3a DNA-(cytosine C5)-methyltransferase
-
Gowher, H., Loutchanwoot, P., Vorobjeva, O., Handa, V., Jurkowska, R. Z., Jurkowski, T. P., Jeltsch, A. (2006) Mutational analysis of the catalytic domain of the murine Dnmt3a DNA-(cytosine C5)-methyltransferase. J Mol Biol 357:928-941.
-
(2006)
J Mol Biol
, vol.357
, pp. 928-941
-
-
Gowher, H.1
Loutchanwoot, P.2
Vorobjeva, O.3
Handa, V.4
Jurkowska, R.Z.5
Jurkowski, T.P.6
Jeltsch, A.7
-
92
-
-
33644849860
-
Accuracy of methylation pattern preservation by the Dnmt1 methyltransferase
-
Goyal, R., Reinhardt, R., Jeltsch, A. (2006) Accuracy of methylation pattern preservation by the Dnmt1 methyltransferase. Nucl Acids Res 34:1182-1188.
-
(2006)
Nucl Acids Res
, vol.34
, pp. 1182-1188
-
-
Goyal, R.1
Reinhardt, R.2
Jeltsch, A.3
-
93
-
-
38749096640
-
On the mechanism of demethylation of 5-methylcytosine in DNA
-
Hamm, S., Just, G., Lacoste, N., Moitessier, N., Szyf, M., Mamer, O. (2007) On the mechanism of demethylation of 5-methylcytosine in DNA. Bioorg Med Chem Lett 18(3):1046-1049.
-
(2007)
Bioorg Med Chem Lett
, vol.18
, Issue.3
, pp. 1046-1049
-
-
Hamm, S.1
Just, G.2
Lacoste, N.3
Moitessier, N.4
Szyf, M.5
Mamer, O.6
-
94
-
-
0035233134
-
Thymine DNA glycosylase
-
Hardeland, U., Bentele, M., Lettieri, T., Steinacher, R., Jiricny, J., Schar, P. (2001) Thymine DNA glycosylase. Prog Nucleic Acid Res Mol Biol 68:235-252.
-
(2001)
Prog Nucleic Acid Res Mol Biol
, vol.68
, pp. 235-252
-
-
Hardeland, U.1
Bentele, M.2
Lettieri, T.3
Steinacher, R.4
Jiricny, J.5
Schar, P.6
-
95
-
-
53649089723
-
The SRA domain of UHRF1 flips 5-methylcytosine out of the DNA helix
-
Hashimoto, H., Horton, J. R., Zhang, X., Bostick, M., Jacobsen, S. E., Cheng, X. (2008) The SRA domain of UHRF1 flips 5-methylcytosine out of the DNA helix. Nature 826(455):826-830.
-
(2008)
Nature
, vol.826
, Issue.455
, pp. 826-830
-
-
Hashimoto, H.1
Horton, J.R.2
Zhang, X.3
Bostick, M.4
Jacobsen, S.E.5
Cheng, X.6
-
96
-
-
0035170113
-
Satellite 2 methylation patterns in normal and ICF syndrome cells and association of hypomethylation with advanced replication
-
Hassan, K. M., Norwood, T., Gimelli, G., Gartler, S. M., Hansen, R. S. (2001) Satellite 2 methylation patterns in normal and ICF syndrome cells and association of hypomethylation with advanced replication. Hum Genet 109(4):452-462.
-
(2001)
Hum Genet
, vol.109
, Issue.4
, pp. 452-462
-
-
Hassan, K.M.1
Norwood, T.2
Gimelli, G.3
Gartler, S.M.4
Hansen, R.S.5
-
97
-
-
0036333103
-
Dnmt3L cooperates with the Dnmt3 family of de novo DNA methyltrannsferases to establish maternal imprints in mice
-
Hata, K., Okano, M., Lei, H., Li, F. (2002) Dnmt3L cooperates with the Dnmt3 family of de novo DNA methyltrannsferases to establish maternal imprints in mice. Development 129:1983-1993.
-
(2002)
Development
, vol.129
, pp. 1983-1993
-
-
Hata, K.1
Okano, M.2
Lei, H.3
Li, F.4
-
98
-
-
0033575886
-
The thymine glycosylase MBD4 can bind to the product of deamination at methylated CpG sites
-
Hendrich, B., Hardeland, U., NG, H.-H., Jiricny, J., Bird, A. (1999) The thymine glycosylase MBD4 can bind to the product of deamination at methylated CpG sites. Nature 401:301-304.
-
(1999)
Nature
, vol.401
, pp. 301-304
-
-
Hendrich, B.1
Hardeland, U.2
Ng, H.-H.3
Jiricny, J.4
Bird, A.5
-
99
-
-
9744251005
-
Biochemistry and biology of DNA mammalian DNA methyltransferases
-
Hermann, A., Gowher, H., Jeltsch, A. (2004a) Biochemistry and biology of DNA mammalian DNA methyltransferases. Curr Mol Life Sci 61:2571-2587.
-
(2004)
Curr Mol Life Sci
, vol.61
, pp. 2571-2587
-
-
Hermann, A.1
Gowher, H.2
Jeltsch, A.3
-
100
-
-
9144256125
-
The Dnmt1 DNA -(cytosine C5)-methyltransferase methylates DNA processivly with high preference for hemimethylated target sites
-
Hermann, A., Goyal, R., Jeltsch, A. (2004b) The Dnmt1 DNA -(cytosine C5)-methyltransferase methylates DNA processivly with high preference for hemimethylated target sites. J Biol Chem 279:48350-48359.
-
(2004)
J Biol Chem
, vol.279
, pp. 48350-48359
-
-
Hermann, A.1
Goyal, R.2
Jeltsch, A.3
-
101
-
-
41549161985
-
The epigenetic origin of aneuploidy
-
Herrera, L. A., Prada, D., Andronegui, M. A., Duenaz-Gonzales, A. (2008) The epigenetic origin of aneuploidy. Curr Genomics 9:43-50.
-
(2008)
Curr Genomics
, vol.9
, pp. 43-50
-
-
Herrera, L.A.1
Prada, D.2
Andronegui, M.A.3
Duenaz-Gonzales, A.4
-
102
-
-
84883141105
-
Epigenetics:a historical overview
-
In:Heard, E. (ed)., The Biomedical & Life Sciences Collection. Henry Stewart Talks Ltd., London. Available at
-
Holliday, R. (2007) Epigenetics:a historical overview. In:Heard, E. (ed). Epigenetics:Concepts, Theories, Paradigms and Mechanisms. The Biomedical & Life Sciences Collection. Henry Stewart Talks Ltd., London. Available at:http://hstalks.com/bio.
-
(2007)
Epigenetics:Concepts, Theories, Paradigms and Mechanisms
-
-
Holliday, R.1
-
103
-
-
0016439429
-
DNA modification mechanisms and gene activity during development
-
Holliday, R., Pugh, J. E. (1975) DNA modification mechanisms and gene activity during development. Science 186:226-232.
-
(1975)
Science
, vol.186
, pp. 226-232
-
-
Holliday, R.1
Pugh, J.E.2
-
104
-
-
84957846754
-
The quantitative separation of purines, pyrimidines, and nucleosides by paper chromatography
-
Hotchkiss, R. D. (1948) The quantitative separation of purines, pyrimidines, and nucleosides by paper chromatography. J Biol Chem 175:315-332.
-
(1948)
J Biol Chem
, vol.175
, pp. 315-332
-
-
Hotchkiss, R.D.1
-
105
-
-
0034499304
-
Recognition and silencing of repeated DNA
-
Hsieh, J., Fire, A. (2000) Recognition and silencing of repeated DNA. Annu Rev Genet 34:187-204.
-
(2000)
Annu Rev Genet
, vol.34
, pp. 187-204
-
-
Hsieh, J.1
Fire, A.2
-
106
-
-
0003414163
-
Epigenetic Inheritance and Evolution:The Lamarckian Dimension
-
Oxford University Press, New York
-
Jablonka, E., Lamb, M. (1995) Epigenetic Inheritance and Evolution:The Lamarckian Dimension. Oxford University Press, New York.
-
(1995)
-
-
Jablonka, E.1
Lamb, M.2
-
107
-
-
0030743612
-
DNA methylation and imprinting:why bother?
-
Jaenisch R. (1997) DNA methylation and imprinting:why bother? Trends Genet 13:323-329.
-
(1997)
Trends Genet
, vol.13
, pp. 323-329
-
-
Jaenisch, R.1
-
108
-
-
0020283636
-
DNA methylation, retroviruses, and embryogenesis
-
Jaenisch, R., Harbers, K., Jahner, D., Stewart, C., Stuhlmann, H. (1982) DNA methylation, retroviruses, and embryogenesis. J Cell Biochem 20:331-336.
-
(1982)
J Cell Biochem
, vol.20
, pp. 331-336
-
-
Jaenisch, R.1
Harbers, K.2
Jahner, D.3
Stewart, C.4
Stuhlmann, H.5
-
109
-
-
0036326660
-
Elevation in S-adenosylhomocysteine and DNA hypomethylation:potential epigenetic mechanism for homocysteine-related pathology
-
James, S. J., Melnyk, S., Pogribna, M., Pogribny, I. P., Candill, M. A. (2002) Elevation in S-adenosylhomocysteine and DNA hypomethylation:potential epigenetic mechanism for homocysteine-related pathology. J Nutr 132:2361S-2366S.
-
(2002)
J Nutr
, vol.132
-
-
James, S.J.1
Melnyk, S.2
Pogribna, M.3
Pogribny, I.P.4
Candill, M.A.5
-
110
-
-
56349142882
-
Abnormal transmethylation/transsulfuration metabolism and DNA hypomethylation among parents of children with autism
-
James, S. J., Melnyk, S., Jernigan, S., Hubanks, A., Rose, S., Gaylor, D. W. (2008) Abnormal transmethylation/transsulfuration metabolism and DNA hypomethylation among parents of children with autism. J Autism Dev Disord 38:1966-1975.
-
(2008)
J Autism Dev Disord
, vol.38
, pp. 1966-1975
-
-
James, S.J.1
Melnyk, S.2
Jernigan, S.3
Hubanks, A.4
Rose, S.5
Gaylor, D.W.6
-
111
-
-
0037007175
-
Beyond Watson and Crick:DNA methylation and molecular enzymology of DNA methylases
-
Jeltsch, A. (2002) Beyond Watson and Crick:DNA methylation and molecular enzymology of DNA methylases. Chem Biol Chem 3:274-293.
-
(2002)
Chem Biol Chem
, vol.3
, pp. 274-293
-
-
Jeltsch, A.1
-
112
-
-
38449104412
-
On the enzymatic properties of Dnmt1:specificity, processivity, mechanism of linear diffusion and allosteric regulation of the enzyme
-
Jeltsch, A. (2006) On the enzymatic properties of Dnmt1:specificity, processivity, mechanism of linear diffusion and allosteric regulation of the enzyme. Epigenetics 1:63-66.
-
(2006)
Epigenetics
, vol.1
, pp. 63-66
-
-
Jeltsch, A.1
-
113
-
-
53549133654
-
Reading and writing methylation
-
Jeltsch, A. (2008) Reading and writing methylation. Nat Struct Mol Biol 15:1003-1004.
-
(2008)
Nat Struct Mol Biol
, vol.15
, pp. 1003-1004
-
-
Jeltsch, A.1
-
114
-
-
33745253953
-
Two substrates are better then one:dual specificities for Dnmt2 methylases
-
Jeltsch, A., Nellen, W., Lyko, F. (2006) Two substrates are better then one:dual specificities for Dnmt2 methylases. Trends Biochem Sci 31(6):306-308.
-
(2006)
Trends Biochem Sci
, vol.31
, Issue.6
, pp. 306-308
-
-
Jeltsch, A.1
Nellen, W.2
Lyko, F.3
-
115
-
-
0035839136
-
Translating the histone code
-
Jenuwein, T., Allis, C. D. (2001) Translating the histone code. Science 293(5532):1074-1080.
-
(2001)
Science
, vol.293
, Issue.5532
, pp. 1074-1080
-
-
Jenuwein, T.1
Allis, C.D.2
-
116
-
-
33947310031
-
Environmental epigenomics and disease susceptibility
-
Jirtle, R. L., Skinner, M. K. (2007) Environmental epigenomics and disease susceptibility. Nat Rev 8(4):253-262.
-
(2007)
Nat Rev
, vol.8
, Issue.4
, pp. 253-262
-
-
Jirtle, R.L.1
Skinner, M.K.2
-
117
-
-
0022032204
-
Altering gene expression with 5-azacytidine
-
Jones, P. A. (1985) Altering gene expression with 5-azacytidine. Cell 40:485-486.
-
(1985)
Cell
, vol.40
, pp. 485-486
-
-
Jones, P.A.1
-
118
-
-
0032960181
-
Cancer epigenetics comes of age
-
Jones, P. A., Laird, P. W. (1999) Cancer epigenetics comes of age. Natl Genet 21:163-167.
-
(1999)
Natl Genet
, vol.21
, pp. 163-167
-
-
Jones, P.A.1
Laird, P.W.2
-
119
-
-
0035839057
-
The role of DNA methylation in mammalian epigenetics
-
Jones, P. A., Takai, D. (2001) The role of DNA methylation in mammalian epigenetics. Science 293:1068-1070.
-
(2001)
Science
, vol.293
, pp. 1068-1070
-
-
Jones, P.A.1
Takai, D.2
-
120
-
-
0018860957
-
Cellular different cytidine analogues and DNA methylation
-
Jones, P. A., Taylor, S. M. (1980) Cellular different cytidine analogues and DNA methylation. Cell 20:185-193.
-
(1980)
Cell
, vol.20
, pp. 185-193
-
-
Jones, P.A.1
Taylor, S.M.2
-
121
-
-
0031837109
-
Methylated DNA and MeCP2 recruit histone deacetylase to repress transcription
-
Jones, P. L., Veenestra, G. J., Wade, P. A., Vermaak, D., Kass, S. U., Landsberger, N., Strouboulis, J., Wolffe, A. P. (1998) Methylated DNA and MeCP2 recruit histone deacetylase to repress transcription. Nat Genet 19:187-191.
-
(1998)
Nat Genet
, vol.19
, pp. 187-191
-
-
Jones, P.L.1
Veenestra, G.J.2
Wade, P.A.3
Vermaak, D.4
Kass, S.U.5
Landsberger, N.6
Strouboulis, J.7
Wolffe, A.P.8
-
122
-
-
0027310491
-
Nuclear extracts of chicken embryos promote an active demethylation of DNA by excision repair of 5-methylcytidine
-
Jost, J. P. (1993) Nuclear extracts of chicken embryos promote an active demethylation of DNA by excision repair of 5-methylcytidine. Proc Natl Acad Sci USA 90:4684-4688.
-
(1993)
Proc Natl Acad Sci USA
, vol.90
, pp. 4684-4688
-
-
Jost, J.P.1
-
123
-
-
0028934977
-
Mechanisms of DNA demethylation in chicken embryos
-
Purification and properties of a 5-methylcytosine-DNA glycosylase
-
Jost, J. P., Siegmann, M., Sun, L., Leung, R., (1995) Mechanisms of DNA demethylation in chicken embryos. Purification and properties of a 5-methylcytosine-DNA glycosylase. J Biol Chem 270(17):9734-9739.
-
(1995)
J Biol Chem
, vol.270
, Issue.17
, pp. 9734-9739
-
-
Jost, J.P.1
Siegmann, M.2
Sun, L.3
Leung, R.4
-
124
-
-
47949107313
-
Human DNMT2 methylates tRNA(Asp) molecules using a DNA methylase-like catalytic mechanism
-
Jurkowski, T. P., Mensburger, M., Phalke, S., Helm, M., Nellen, W., Reuter, G., Jeltsch, A. (2008) Human DNMT2 methylates tRNA(Asp) molecules using a DNA methylase-like catalytic mechanism. RNA 14(8):1663-1670.
-
(2008)
RNA
, vol.14
, Issue.8
, pp. 1663-1670
-
-
Jurkowski, T.P.1
Mensburger, M.2
Phalke, S.3
Helm, M.4
Nellen, W.5
Reuter, G.6
Jeltsch, A.7
-
125
-
-
3042584653
-
Essential role for de novo DNA methyltransferase Dnmt3a in paternal and maternal imprinting
-
Kaneda, M., Okano, M., Hata, K., Sado, T., Tsujimoto, N., Li, E., Sasaki, H. (2004) Essential role for de novo DNA methyltransferase Dnmt3a in paternal and maternal imprinting. Nature 429(6994):900-903.
-
(2004)
Nature
, vol.429
, Issue.6994
, pp. 900-903
-
-
Kaneda, M.1
Okano, M.2
Hata, K.3
Sado, T.4
Tsujimoto, N.5
Li, E.6
Sasaki, H.7
-
126
-
-
0030038608
-
A role for nuclear NF-kappaB in B-cell-specific demethylation of the Igkappa locus
-
Kirillov, A., Kistler, B., Mostoslavsky, R., Cedar, H., Wirth, T., Bergman, Y. (1996) A role for nuclear NF-kappaB in B-cell-specific demethylation of the Igkappa locus. Nat Genet 13:435-441.
-
(1996)
Nat Genet
, vol.13
, pp. 435-441
-
-
Kirillov, A.1
Kistler, B.2
Mostoslavsky, R.3
Cedar, H.4
Wirth, T.5
Bergman, Y.6
-
127
-
-
0028010888
-
HhaI methyltransferase flips its target base out of the DNA helix
-
Klimasauskas, S., Kumar, S., Roberts, R. J., Cheng, X. (1994) HhaI methyltransferase flips its target base out of the DNA helix. Cell 76(2):357-369.
-
(1994)
Cell
, vol.76
, Issue.2
, pp. 357-369
-
-
Klimasauskas, S.1
Kumar, S.2
Roberts, R.J.3
Cheng, X.4
-
128
-
-
32344450824
-
Genomic DNA methylation:the mark and its mediators
-
Klose, R. J., Bird, A. P. (2006) Genomic DNA methylation:the mark and its mediators. Trends Biochem Sci 31:89-97.
-
(2006)
Trends Biochem Sci
, vol.31
, pp. 89-97
-
-
Klose, R.J.1
Bird, A.P.2
-
129
-
-
0028226225
-
The DNA (cytosine-5) methyltransferases
-
Kumar, S., Cheng, X., Klimasauskas, S., Mi, S., Posfai, J., Roberts, R. J., Wilson, G. G. (1994) The DNA (cytosine-5) methyltransferases. Nucleic Acids Res 22(1):1-10.
-
(1994)
Nucleic Acids Res
, vol.22
, Issue.1
, pp. 1-10
-
-
Kumar, S.1
Cheng, X.2
Klimasauskas, S.3
Mi, S.4
Posfai, J.5
Roberts, R.J.6
Wilson, G.G.7
-
130
-
-
0242550723
-
A Dnmt2-like protein mediates DNA methylation in Drosophila Development
-
Kunert, N., Marhold, J., Stanke, J., Stach, D., Lyko, F. (2003) A Dnmt2-like protein mediates DNA methylation in Drosophila Development 130(21):5083-5090.
-
(2003)
, vol.130
, Issue.21
, pp. 5083-5090
-
-
Kunert, N.1
Marhold, J.2
Stanke, J.3
Stach, D.4
Lyko, F.5
-
131
-
-
0038576158
-
The power and the promise of DNA methylation markers
-
Laird, P.W. (2003) The power and the promise of DNA methylation markers. Nat Rev Cancer 3:253.
-
(2003)
Nat Rev Cancer
, vol.3
, pp. 253
-
-
Laird, P.W.1
-
132
-
-
2042437650
-
Initial sequencing and analysis of the human genome
-
Lander E. S., Linton L. M., Birren B., Nusbaum C., Zody M. C., Baldwin J., Devon K., Dewar K., Doyle M., Fitzhugh W., et al. (2001) Initial sequencing and analysis of the human genome. Nature 409:860-921.
-
(2001)
Nature
, vol.409
, pp. 860-921
-
-
Lander, E.S.1
Linton, L.M.2
Birren, B.3
Nusbaum, C.4
Zody, M.C.5
Baldwin, J.6
Devon, K.7
Dewar, K.8
Doyle, M.9
Fitzhugh, W.10
-
133
-
-
10744230544
-
Suv39h-mediated histone H3 lysine 9 methylation directs DNA methylation to major satellite repeats at pericentromeric heterochromatic
-
Lehnertz, B., Ueda, Y., Derijck, A. A., Braunschweig, U., Perez-Burgos, L., Kubicek, S., Chen, T., Li, E., Jenuwein, T., Peters, A. H. (2003) Suv39h-mediated histone H3 lysine 9 methylation directs DNA methylation to major satellite repeats at pericentromeric heterochromatic. Curr Biol 13:1192-1200.
-
(2003)
Curr Biol
, vol.13
, pp. 1192-1200
-
-
Lehnertz, B.1
Ueda, Y.2
Derijck, A.A.3
Braunschweig, U.4
Perez-Burgos, L.5
Kubicek, S.6
Chen, T.7
Li, E.8
Jenuwein, T.9
Peters, A.H.10
-
134
-
-
0026439115
-
A targeting sequence directs DNA methyltransferase to sites of DNA replication in mammalian nuclei
-
Leonhardt, H., Page, A. W., Weier, H.-U., Bestor, T. H. (1992) A targeting sequence directs DNA methyltransferase to sites of DNA replication in mammalian nuclei. Cell 71:865-874.
-
(1992)
Cell
, vol.71
, pp. 865-874
-
-
Leonhardt, H.1
Page, A.W.2
Weier, H.-U.3
Bestor, T.H.4
-
135
-
-
34249111173
-
DNA methylation in mammals
-
In:D. C. Allis, T. Jenuwein, D. Reinberg, and M.-L. Caparros (eds), Epigenetics. Cold Spring Harbor Laboratory Press, New York
-
Li, E., Bird, A. P. (2007) DNA methylation in mammals. In:D. C. Allis, T. Jenuwein, D. Reinberg, and M.-L. Caparros (eds) Epigenetics. Cold Spring Harbor Laboratory Press, New York.
-
(2007)
-
-
Li, E.1
Bird, A.P.2
-
136
-
-
0026708177
-
Targeted mutation of the DNA methyltransferase gene results in embryonic lethality
-
Li, E., Bestor, T. H., Jaenisch, R. (1992) Targeted mutation of the DNA methyltransferase gene results in embryonic lethality. Cell 69:915-926.
-
(1992)
Cell
, vol.69
, pp. 915-926
-
-
Li, E.1
Bestor, T.H.2
Jaenisch, R.3
-
137
-
-
33846909036
-
Association of Dnmt3a and thymine DNA glycosylase links DNA methylation with base-excision repair
-
Li, Y.-Q., Zhou, P.-Z., Zheng, X.-D., Walsh, C. P., Xu, G.-L. (2006) Association of Dnmt3a and thymine DNA glycosylase links DNA methylation with base-excision repair. Nucl Acids Res 35(2):390-400.
-
(2006)
Nucl Acids Res
, vol.35
, Issue.2
, pp. 390-400
-
-
Li, Y.-Q.1
Zhou, P.-Z.2
Zheng, X.-D.3
Walsh, C.P.4
Xu, G.-L.5
-
138
-
-
0000476915
-
An N-glycosylase from Escherichia coli that releases free uracyl from DNA containing deaminated cytosine residues
-
Lindahl, T. (1974) An N-glycosylase from Escherichia coli that releases free uracyl from DNA containing deaminated cytosine residues. Proc Natl Acad Sci USA 71:3649-3653.
-
(1974)
Proc Natl Acad Sci USA
, vol.71
, pp. 3649-3653
-
-
Lindahl, T.1
-
139
-
-
70450217879
-
Human DNA methylomes at base resolution show widespread epigenomic differences
-
Lister, R., Pelizzola, M., Dowen, R. H., Hawkins, R. D., Hon, G., Tonti-Filippini, J., Nery, J. R., Lee, L., Ye, Z., Ngo, Q.-M., Edsall, L., Antosiewicz-Bourget, J., Stewart, R., Ruotti, V., Millar, A. H., Thomson, J. A., Ren, B., Ecker, J. R. (2009) Human DNA methylomes at base resolution show widespread epigenomic differences. Nature 462:315-322.
-
(2009)
Nature
, vol.462
, pp. 315-322
-
-
Lister, R.1
Pelizzola, M.2
Dowen, R.H.3
Hawkins, R.D.4
Hon, G.5
Tonti-Filippini, J.6
Nery, J.R.7
Lee, L.8
Ye, Z.9
Ngo, Q.-M.10
Edsall, L.11
Antosiewicz-Bourget, J.12
Stewart, R.13
Ruotti, V.14
Millar, A.H.15
Thomson, J.A.16
Ren, B.17
Ecker, J.R.18
-
140
-
-
0035831505
-
The dynamics of myogenin site-specific demethylation is strongly correlated with its expression and with muscle differentiation
-
Lucarelli, M., Fuso, A., Strom, R., Scarpa, S. (2001) The dynamics of myogenin site-specific demethylation is strongly correlated with its expression and with muscle differentiation. J Biol Chem 276:7500-7506.
-
(2001)
J Biol Chem
, vol.276
, pp. 7500-7506
-
-
Lucarelli, M.1
Fuso, A.2
Strom, R.3
Scarpa, S.4
-
141
-
-
0034735780
-
DNA methylation in Drosophila melanogaster
-
Lyko, F., Ramsahoe, B. H., Jaenisch, R. (2000) DNA methylation in Drosophila melanogaster. Nature 408:538-540.
-
(2000)
Nature
, vol.408
, pp. 538-540
-
-
Lyko, F.1
Ramsahoe, B.H.2
Jaenisch, R.3
-
142
-
-
0035148664
-
Lowering S-adenosylmethionine levels in Escherichia coli modulates C-to-T transition mutations
-
Macinyre, G., Atwood, C. V., Cupples, C. G. (2001) Lowering S-adenosylmethionine levels in Escherichia coli modulates C-to-T transition mutations. J Bacteriol 183(3):921-927.
-
(2001)
J Bacteriol
, vol.183
, Issue.3
, pp. 921-927
-
-
Macinyre, G.1
Atwood, C.V.2
Cupples, C.G.3
-
143
-
-
0028120256
-
Enzymatic DNA methylation as a mechanism of aging
-
Mazin, A. L. (1994) Enzymatic DNA methylation as a mechanism of aging. Mol Biol 28(1):21-52.
-
(1994)
Mol Biol
, vol.28
, Issue.1
, pp. 21-52
-
-
Mazin, A.L.1
-
144
-
-
0029162202
-
Life span prediction from the rate of age-related DNA demethylation in normal and cancer cell lines
-
Mazin, A. L. (1995) Life span prediction from the rate of age-related DNA demethylation in normal and cancer cell lines. Exp Gerontol 30(5):475-485.
-
(1995)
Exp Gerontol
, vol.30
, Issue.5
, pp. 475-485
-
-
Mazin, A.L.1
-
145
-
-
69049086542
-
Suicidal function of DNA methylation in age-dependent genome disintegration
-
Mazin, A. L. (2009) Suicidal function of DNA methylation in age-dependent genome disintegration. Ageing Res Rev 8(4):314-327.
-
(2009)
Ageing Res Rev
, vol.8
, Issue.4
, pp. 314-327
-
-
Mazin, A.L.1
-
146
-
-
0024342686
-
Identification of a mammalian protein that binds specifically to DNA containing methylated CpGs
-
Meehan, R. R., Lewis, J. D., Mc Kay, S., Kleiner, E. L., Bird, A. P. (1989) Identification of a mammalian protein that binds specifically to DNA containing methylated CpGs. Cell 58:499-507.
-
(1989)
Cell
, vol.58
, pp. 499-507
-
-
Meehan, R.R.1
Lewis, J.D.2
Mc Kay, S.3
Kleiner, E.L.4
Bird, A.P.5
-
147
-
-
70449093724
-
Np95 interacts with de novo DNA methyltransferases, Dnmt3a and Dnmt3b, and mediates epigenetic silencing of viral CMV promoter in embryonic stem cells
-
Meilinger, D., Fellinger, K., Bultmann, S., Rothbauer, U., Bonapace, I. M., Klinkert,W. E. F., Spada, F., Leonhardt, H. (2009) Np95 interacts with de novo DNA methyltransferases, Dnmt3a and Dnmt3b, and mediates epigenetic silencing of viral CMV promoter in embryonic stem cells. Eur Mol Biol Org 10(11):1259-1264.
-
(2009)
Eur Mol Biol Org
, vol.10
, Issue.11
, pp. 1259-1264
-
-
Meilinger, D.1
Fellinger, K.2
Bultmann, S.3
Rothbauer, U.4
Bonapace, I.M.5
Klinkert, W.E.F.6
Spada, F.7
Leonhardt, H.8
-
148
-
-
40449123137
-
Cyclical DNA methylation of transcriptionally active promoter
-
Metivier, R., Gallais, R., Tiffoche, C., LE Peron, C., Kurkowska, R. Z., Carmouche, R. P., Ibberson, D., Barath, P., Demay, F., Reid, G., Benes, V., Jeltsch, A., Gannon, F., salbert, G. (2008) Cyclical DNA methylation of transcriptionally active promoter. Nature 452(7183):45-50.
-
(2008)
Nature
, vol.452
, Issue.7183
, pp. 45-50
-
-
Metivier, R.1
Gallais, R.2
Tiffoche, C.3
Le Peron, C.4
Kurkowska, R.Z.5
Carmouche, R.P.6
Ibberson, D.7
Barath, P.8
Demay, F.9
Reid, G.10
Benes, V.11
Jeltsch, A.12
Gannon, F.13
Salbert, G.14
-
149
-
-
84956807857
-
Five not four:history and significance of the fifth base
-
In:S. Beck and A. Olek (eds),, Wiley Academic Press, New York
-
Millar, D. S., Holliday, R., Grigg, G. W. (2003) Five not four:history and significance of the fifth base. In:S. Beck and A. Olek (eds), The Epigenome:Molecular Hide and Seek. Wiley Academic Press, New York, pp. 1-18.
-
(2003)
The Epigenome:Molecular Hide and Seek
, pp. 1-18
-
-
Millar, D.S.1
Holliday, R.2
Grigg, G.W.3
-
150
-
-
17444409344
-
Epigenetic reprogramming in mammals
-
Morgan, H. D., Santos, F., Green, K., Dean, W., Reik, W. (2005) Epigenetic reprogramming in mammals. Hum Mol Genet 14(1):R47-R58.
-
(2005)
Hum Mol Genet
, vol.14
, Issue.1
-
-
Morgan, H.D.1
Santos, F.2
Green, K.3
Dean, W.4
Reik, W.5
-
151
-
-
0032574977
-
Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex
-
Nan, X., Ng, H. H., Johnson, C. A., Laherty, C. D., Turner, B. M., Eisenman, R. N., Bird, A. (1998) Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex. Nature 393(6683):386-389.
-
(1998)
Nature
, vol.393
, Issue.6683
, pp. 386-389
-
-
Nan, X.1
Ng, H.H.2
Johnson, C.A.3
Laherty, C.D.4
Turner, B.M.5
Eisenman, R.N.6
Bird, A.7
-
152
-
-
15844419144
-
Cloning and expression of human G/T mismatch-specific thymine DNA glycosylase
-
Nedermann, P., Gallinari, P., Lettieri, T. (1996) Cloning and expression of human G/T mismatch-specific thymine DNA glycosylase. J Biol Chem 271:12767-12774.
-
(1996)
J Biol Chem
, vol.271
, pp. 12767-12774
-
-
Nedermann, P.1
Gallinari, P.2
Lettieri, T.3
-
153
-
-
0032871399
-
MBD2 is a transcriptional repressor belonging to the MeCP1 histone deacetylase complex
-
Ng, H. H., Zhang, Y., Hendrich, B., Johnson, C. A., Turner, B. M., Erdjument-Bromage, H., Tempst, P., Reinberg, D., Bird, A. (1999) MBD2 is a transcriptional repressor belonging to the MeCP1 histone deacetylase complex. Nat Genet 23(1):58-61.
-
(1999)
Nat Genet
, vol.23
, Issue.1
, pp. 58-61
-
-
Ng, H.H.1
Zhang, Y.2
Hendrich, B.3
Johnson, C.A.4
Turner, B.M.5
Erdjument-Bromage, H.6
Tempst, P.7
Reinberg, D.8
Bird, A.9
-
154
-
-
0036327615
-
Diet, methyl donors and DNA methylation:interactions between dietary folate, methionine and choline
-
Niculescu, M. D., Zeisel S. H. (2002) Diet, methyl donors and DNA methylation:interactions between dietary folate, methionine and choline. J Nutr 132(8):2333S.
-
(2002)
J Nutr
, vol.132
, Issue.8
-
-
Niculescu, M.D.1
Zeisel, S.H.2
-
155
-
-
30744479491
-
Dietary choline deficiency alters global and gene-specific DNA methylation in the developing hippocampus of mouse fetal brains
-
Niculescu, M. D., Craciunescu, C. N., Zeisel, S. H. (2006) Dietary choline deficiency alters global and gene-specific DNA methylation in the developing hippocampus of mouse fetal brains. FASEB J 20:43-49.
-
(2006)
FASEB J
, vol.20
, pp. 43-49
-
-
Niculescu, M.D.1
Craciunescu, C.N.2
Zeisel, S.H.3
-
156
-
-
60549088692
-
Active demethylation and DNA repair
-
Niehs, C. (2009) Active demethylation and DNA repair. Differentiation 77(1):1-11.
-
(2009)
Differentiation
, vol.77
, Issue.1
, pp. 1-11
-
-
Niehs, C.1
-
157
-
-
0031860739
-
Cloning and caracterisation of a family of novel mammalian DNA(cytosine-5)methyltransferases
-
Okano, M., Xie, S., Li, E. (1998) Cloning and caracterisation of a family of novel mammalian DNA(cytosine-5)methyltransferases. Nat Genet 19:219-220.
-
(1998)
Nat Genet
, vol.19
, pp. 219-220
-
-
Okano, M.1
Xie, S.2
Li, E.3
-
158
-
-
0033615717
-
DNA methyl transferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development
-
Okano, M., Bell, D. W., Haber, D. A., Li, E. (1999) DNA methyl transferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development. Cell 99:247-257.
-
(1999)
Cell
, vol.99
, pp. 247-257
-
-
Okano, M.1
Bell, D.W.2
Haber, D.A.3
Li, E.4
-
159
-
-
45449114804
-
The colorful history of active DNA demethylation
-
Ooi, S. K. T., Bestor, T. H. (2008) The colorful history of active DNA demethylation. Cell 133:1145-1148.
-
(2008)
Cell
, vol.133
, pp. 1145-1148
-
-
Ooi, S.K.T.1
Bestor, T.H.2
-
160
-
-
0025637814
-
Dynamics of demethylation and activation of the alpha-actin gene in myoblasts
-
Paroush, Z., Keshet, I., Yisraeli, J., Cedar, H. (1990) Dynamics of demethylation and activation of the alpha-actin gene in myoblasts. Cell 63:1220-1237.
-
(1990)
Cell
, vol.63
, pp. 1220-1237
-
-
Paroush, Z.1
Keshet, I.2
Yisraeli, J.3
Cedar, H.4
-
161
-
-
34250857552
-
DNA study forces rethink of what it means to be a gene
-
Pennisi, E. (2007) DNA study forces rethink of what it means to be a gene. Science 316(5831):1556-1557.
-
(2007)
Science
, vol.316
, Issue.5831
, pp. 1556-1557
-
-
Pennisi, E.1
-
162
-
-
10044235379
-
Hyperhomocysteinemia and the cardiovascular disease of uremia
-
Perna, A. F., Satta, E., Lombardi, C., Acanfora, F., Ingrosso, D., Desanto, N. G. (2004) Hyperhomocysteinemia and the cardiovascular disease of uremia. Nutr Res 24(10):839-849.
-
(2004)
Nutr Res
, vol.24
, Issue.10
, pp. 839-849
-
-
Perna, A.F.1
Satta, E.2
Lombardi, C.3
Acanfora, F.4
Ingrosso, D.5
Desanto, N.G.6
-
163
-
-
0345256406
-
Long range silencing and position effects at telomeres and centromeres:parallels and differences
-
Perrod, S., Gasser, S. M. (2003) Long range silencing and position effects at telomeres and centromeres:parallels and differences. Cell Mol Life Sci 60:2303-2318.
-
(2003)
Cell Mol Life Sci
, vol.60
, pp. 2303-2318
-
-
Perrod, S.1
Gasser, S.M.2
-
164
-
-
0035283058
-
Human morbid genetics revisited:relevance of epigenetics
-
Petronis, A. (2001) Human morbid genetics revisited:relevance of epigenetics. Trends Genet 17:142-146.
-
(2001)
Trends Genet
, vol.17
, pp. 142-146
-
-
Petronis, A.1
-
165
-
-
0035260633
-
Confounded cytosine! Tinckering and the evolution of DNA
-
Poole, A., Penny, D., Sjoberg, B.-M. (2001) Confounded cytosine! Tinckering and the evolution of DNA. Nat RevMol Cell Biol 2:147-151.
-
(2001)
Nat RevMol Cell Biol
, vol.2
, pp. 147-151
-
-
Poole, A.1
Penny, D.2
Sjoberg, B.-M.3
-
166
-
-
0032722062
-
Recombinant human DNA (cytosine-5) methyltransferase
-
Pradhan, S., Bacolla, A., Wells, R. D., Roberts, R. J. (1999) Recombinant human DNA (cytosine-5) methyltransferase. I. Expression, purification, and comparison of de novo and maintenance methylation. J Biol Chem 274:33002-33010.
-
(1999)
I. Expression, purification, and comparison of de novo and maintenance methylation. J Biol Chem
, vol.274
, pp. 33002-33010
-
-
Pradhan, S.1
Bacolla, A.2
Wells, R.D.3
Roberts, R.J.4
-
167
-
-
38149019842
-
Pericentric heterochromatin:dynamic organization during early development in mammals
-
Probst, A. V., Almouzni, G. (2008) Pericentric heterochromatin:dynamic organization during early development in mammals. Differentiation 76:15-23.
-
(2008)
Differentiation
, vol.76
, pp. 15-23
-
-
Probst, A.V.1
Almouzni, G.2
-
168
-
-
57649196594
-
DNA demethylation in zebrafish involves the coupling of a deaminase, a glycosylase and Gadd45
-
Rai, K., Huggins, IJ., James, S. R., Karpf, A. R., Jones, D. A., Cairns, B. R. (2008) DNA demethylation in zebrafish involves the coupling of a deaminase, a glycosylase and Gadd45. Cell 135:1200-1212.
-
(2008)
Cell
, vol.135
, pp. 1200-1212
-
-
Rai, K.1
Huggins, I.J.2
James, S.R.3
Karpf, A.R.4
Jones, D.A.5
Cairns, B.R.6
-
169
-
-
0032991506
-
DNA methylation is a reversible biological signal
-
Ramachandani, S., Bhatthacharaya, S. K., Cervoni, N., Szyf, M. (1999) DNA methylation is a reversible biological signal. Proc Natl Acad Sci USA 76:6107-6112.
-
(1999)
Proc Natl Acad Sci USA
, vol.76
, pp. 6107-6112
-
-
Ramachandani, S.1
Bhatthacharaya, S.K.2
Cervoni, N.3
Szyf, M.4
-
170
-
-
0033805888
-
Genomic DNA methylation decreases in response to moderate folate depletion in elderly women
-
Rampersaud, G., Kauwell, G. P. A., Hutson, A. D., Cerda, J. J., Bailey, L. B. (2000) Genomic DNA methylation decreases in response to moderate folate depletion in elderly women. Am J Clin Nutr 72(4):998-1003.
-
(2000)
Am J Clin Nutr
, vol.72
, Issue.4
, pp. 998-1003
-
-
Rampersaud, G.1
Kauwell, G.P.A.2
Hutson, A.D.3
Cerda, J.J.4
Bailey, L.B.5
-
171
-
-
0034625064
-
Non-CpG methylation is prevalent in embryonic stem cells and may be mediated by DNA methyltransferase 3a
-
Ramsahoye, B. H., Biniszkiewicz, D., Lyko, F., Clark, V., Bird, A. P., Jaenisch, R. (2000) Non-CpG methylation is prevalent in embryonic stem cells and may be mediated by DNA methyltransferase 3a. Proc Natl Acad Sci USA 97:5237-5242.
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 5237-5242
-
-
Ramsahoye, B.H.1
Biniszkiewicz, D.2
Lyko, F.3
Clark, V.4
Bird, A.P.5
Jaenisch, R.6
-
172
-
-
33645389087
-
N6-methyladenine:the other methylated base of DNA
-
Ratel, D., Ravanat, J. L., Berger, F., Wion, D. (2006) N6-methyladenine:the other methylated base of DNA. BioEssays 28:309-315.
-
(2006)
BioEssays
, vol.28
, pp. 309-315
-
-
Ratel, D.1
Ravanat, J.L.2
Berger, F.3
Wion, D.4
-
173
-
-
23444446431
-
DNA methylation epigenetic control of gene expression
-
Razin, A., Kantor, B. (2005) DNA methylation epigenetic control of gene expression. Prog Mol Subcell Biol 38:151-167.
-
(2005)
Prog Mol Subcell Biol
, vol.38
, pp. 151-167
-
-
Razin, A.1
Kantor, B.2
-
174
-
-
0019318994
-
DNA methylation and gene function
-
Razin, A., Riggs, A. D. (1980) DNA methylation and gene function. Science 210(4470):604-610.
-
(1980)
Science
, vol.210
, Issue.4470
, pp. 604-610
-
-
Razin, A.1
Riggs, A.D.2
-
176
-
-
34249279527
-
Stability and flexibility of epigenetic gene reprogramming in mammalian development
-
Reik, W. (2007) Stability and flexibility of epigenetic gene reprogramming in mammalian development. Nature 447:425-432.
-
(2007)
Nature
, vol.447
, pp. 425-432
-
-
Reik, W.1
-
177
-
-
0035234557
-
Genomic imprinting:parental influence on the genome
-
Reik, W., Walter, J. (2001) Genomic imprinting:parental influence on the genome. Nat Rev Genet. 2:21-32.
-
(2001)
Nat Rev Genet.
, vol.2
, pp. 21-32
-
-
Reik, W.1
Walter, J.2
-
178
-
-
0035839126
-
Epigenetic reprogramming in mammalian development
-
Reik, W., Dean, W., Walter, J. (2001) Epigenetic reprogramming in mammalian development. Science 293(5532):1089-1093.
-
(2001)
Science
, vol.293
, Issue.5532
, pp. 1089-1093
-
-
Reik, W.1
Dean, W.2
Walter, J.3
-
179
-
-
33646193822
-
Inherited epigenetic variation-revisiting soft inheritance
-
Richards, E. J. (2006) Inherited epigenetic variation-revisiting soft inheritance. Nat Rev Genet 7:395-401.
-
(2006)
Nat Rev Genet
, vol.7
, pp. 395-401
-
-
Richards, E.J.1
-
180
-
-
52949098309
-
Human telomere structure and biology
-
Riethman, H. (2008) Human telomere structure and biology. Annu Rev Genomics Hum Genet 9:1-19.
-
(2008)
Annu Rev Genomics Hum Genet
, vol.9
, pp. 1-19
-
-
Riethman, H.1
-
181
-
-
0016692220
-
X inactivation, differentiation and DNA methylation
-
Riggs, A. D. (1975) X inactivation, differentiation and DNA methylation. Cytogenet Cell Genet 14:9-25.
-
(1975)
Cytogenet Cell Genet
, vol.14
, pp. 9-25
-
-
Riggs, A.D.1
-
182
-
-
0347719444
-
Methylation and epigenetic fidelity
-
Riggs, A. D., Xiong, Z. (2004) Methylation and epigenetic fidelity. Proc Natl Acad Sci USA 101(10):4-5.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, Issue.10
, pp. 4-5
-
-
Riggs, A.D.1
Xiong, Z.2
-
184
-
-
0037068372
-
DNA methylation and chromatin-unraveling the tangled web
-
Robertson, K. D. (2002) DNA methylation and chromatin-unraveling the tangled web. Oncogene 22(35):5361-5379.
-
(2002)
Oncogene
, vol.22
, Issue.35
, pp. 5361-5379
-
-
Robertson, K.D.1
-
186
-
-
0033153303
-
The human DNA methyltransferases (DNMTs) 1, 3a and 3b:coordinate mRNA expression in normal tissues and overexpression in tumors
-
Robertson, K. D., Uzvolgi, E., Lian, G., Talmage, C., Sumegi, J., Gonzales, F. A., Jones, P. A. (1999) The human DNA methyltransferases (DNMTs) 1, 3a and 3b:coordinate mRNA expression in normal tissues and overexpression in tumors. Nucleic Acids Res 27(11):2291-2298.
-
(1999)
Nucleic Acids Res
, vol.27
, Issue.11
, pp. 2291-2298
-
-
Robertson, K.D.1
Uzvolgi, E.2
Lian, G.3
Talmage, C.4
Sumegi, J.5
Gonzales, F.A.6
Jones, P.A.7
-
187
-
-
0020582853
-
On the mechanism of the inhibition of DNA-cytosine methyltransferase by cytosine analogs
-
Santi, D. V., Garrett, C. E., Barr, P. Y. (1983) On the mechanism of the inhibition of DNA-cytosine methyltransferase by cytosine analogs. Cell 33:9-10.
-
(1983)
Cell
, vol.33
, pp. 9-10
-
-
Santi, D.V.1
Garrett, C.E.2
Barr, P.Y.3
-
188
-
-
26644445688
-
The prima donna of epigenetics:the regulation of gene expression by DNA methylation
-
Santos, K. F., Mazzola, T. N., Carvalho, H. F. (2005) The prima donna of epigenetics:the regulation of gene expression by DNA methylation. Braz J Med Biol Res 38(10):1531-1541.
-
(2005)
Braz J Med Biol Res
, vol.38
, Issue.10
, pp. 1531-1541
-
-
Santos, K.F.1
Mazzola, T.N.2
Carvalho, H.F.3
-
189
-
-
0015060276
-
The control of gene function in cell differentiation and embryogenesis
-
Scarano, E. (1971) The control of gene function in cell differentiation and embryogenesis. Adv Cytopharmacol 1:13-24.
-
(1971)
Adv Cytopharmacol
, vol.1
, pp. 13-24
-
-
Scarano, E.1
-
190
-
-
74049130225
-
Solving the Dnmt2 enigma
-
Schaefer, M., Lyko, F. (2010) Solving the Dnmt2 enigma. Chromosoma 119:35-40.
-
(2010)
Chromosoma
, vol.119
, pp. 35-40
-
-
Schaefer, M.1
Lyko, F.2
-
191
-
-
70350234722
-
Azacytidine inhibits RNA methylation at DNMT2 target sites in human cancer cell lines
-
Schaefer, M., Hagemann, S., Hanna, K., Lyko, F. (2009) Azacytidine inhibits RNA methylation at DNMT2 target sites in human cancer cell lines. Cancer Res 69:8127-8132.
-
(2009)
Cancer Res
, vol.69
, pp. 8127-8132
-
-
Schaefer, M.1
Hagemann, S.2
Hanna, K.3
Lyko, F.4
-
192
-
-
34548130797
-
Global hypomethylation of peripheral leukocyte DNA in male patients with schizophrenia:a potential link between epigenetics and schizophrenia
-
Schimabukuro, M., Sasaki, T., Imamura, A., Tsujita, T., Fuke, C., Umekage, T., Tochigi, M., Hiramatsu, K., Miyazaki, T., Oda, T., Sugimoto, J., Jibbo, Y., Okazaki, Y. (2007) Global hypomethylation of peripheral leukocyte DNA in male patients with schizophrenia:a potential link between epigenetics and schizophrenia. J Psychiatr Res 41(12):1042-1046.
-
(2007)
J Psychiatr Res
, vol.41
, Issue.12
, pp. 1042-1046
-
-
Schimabukuro, M.1
Sasaki, T.2
Imamura, A.3
Tsujita, T.4
Fuke, C.5
Umekage, T.6
Tochigi, M.7
Hiramatsu, K.8
Miyazaki, T.9
Oda, T.10
Sugimoto, J.11
Jibbo, Y.12
Okazaki, Y.13
-
193
-
-
8644287437
-
Evidence for Eviction and Rapid Deposition of Histones upon Transcriptional Elongation by RNA Polymerase II
-
Schwabish, M. A., Struhl, K. (2004) Evidence for Eviction and Rapid Deposition of Histones upon Transcriptional Elongation by RNA Polymerase II. Molecular and Cellular Biology 24(23):10111-10117.
-
(2004)
Molecular and Cellular Biology
, vol.24
, Issue.23
, pp. 10111-10117
-
-
Schwabish, M.A.1
Struhl, K.2
-
194
-
-
33750353597
-
Structural and functional dynamics of human centromeric chromatin
-
Schueler, M. G., Sullivan, B. A. (2006) Structural and functional dynamics of human centromeric chromatin. Annu Rev Genomics Hum Genet 7:301-313.
-
(2006)
Annu Rev Genomics Hum Genet
, vol.7
, pp. 301-313
-
-
Schueler, M.G.1
Sullivan, B.A.2
-
195
-
-
36849072573
-
The SRA protein Np95 mediates epigenetic inheritance by recruiting Dnmt1 to methylated DNA
-
Sharif, J., Muto, M., Takebayashi, S., Suetake, I., Iwamatsu, A., Endo, T. A., Shinga, J., Mizutani-Koseki, Y., Toyoda, T., Okamurakoseki, K., Tajima, S., Mitsuya, K., Okana, M., Koseki, H. (2007) The SRA protein Np95 mediates epigenetic inheritance by recruiting Dnmt1 to methylated DNA. Nature 450:908-912.
-
(2007)
Nature
, vol.450
, pp. 908-912
-
-
Sharif, J.1
Muto, M.2
Takebayashi, S.3
Suetake, I.4
Iwamatsu, A.5
Endo, T.A.6
Shinga, J.7
Mizutani-Koseki, Y.8
Toyoda, T.9
Okamurakoseki, K.10
Tajima, S.11
Mitsuya, K.12
Okana, M.13
Koseki, H.14
-
196
-
-
0028358421
-
The rate of hydrolytic deamination of 5-methylcytosine in double-stranded DNA
-
Shen, J. C., Rideout, W. M., Jones, P. A. (1994) The rate of hydrolytic deamination of 5-methylcytosine in double-stranded DNA. Nucleic Acids Res 22(6):972-976.
-
(1994)
Nucleic Acids Res
, vol.22
, Issue.6
, pp. 972-976
-
-
Shen, J.C.1
Rideout, W.M.2
Jones, P.A.3
-
197
-
-
3242772090
-
DNA methylation profiles of CpG islands for cellular differentiation and development in mammals
-
Shiota, K. (2004) DNA methylation profiles of CpG islands for cellular differentiation and development in mammals. Cytogenet Genome Res 105:325-334.
-
(2004)
Cytogenet Genome Res
, vol.105
, pp. 325-334
-
-
Shiota, K.1
-
198
-
-
20344385787
-
Epigenetic transgenerational actions of endocrine disruptors and male fertility
-
Skinner, M. K. (2005) Epigenetic transgenerational actions of endocrine disruptors and male fertility. Science 308:1466-1469.
-
(2005)
Science
, vol.308
, pp. 1466-1469
-
-
Skinner, M.K.1
-
199
-
-
33947303168
-
Transposable elements and the epigenetic regulation of the genome
-
Slotkin, K. R., Martienssen, R. (2007) Transposable elements and the epigenetic regulation of the genome. Nat Rev Genet 8(4):272-285.
-
(2007)
Nat Rev Genet
, vol.8
, Issue.4
, pp. 272-285
-
-
Slotkin, K.R.1
Martienssen, R.2
-
200
-
-
0026523796
-
Mechanism of human methyl-directed DNA methyltransferase and the fidelity of cytosine methylation
-
Smith, S. S., Bruce, E. K., Sowers, L. C., Newman, E. M. (1992) Mechanism of human methyl-directed DNA methyltransferase and the fidelity of cytosine methylation. Proc Natl Acad Sci USA 89:4744-4748.
-
(1992)
Proc Natl Acad Sci USA
, vol.89
, pp. 4744-4748
-
-
Smith, S.S.1
Bruce, E.K.2
Sowers, L.C.3
Newman, E.M.4
-
201
-
-
33847348016
-
DNMT1 but not its interaction with the replication machinery is required for maintenance of DNA methylation in human cells
-
Spada, F., Haemmer, A., Kuch, D., Rothbauer, U., Schermrllrh, L., Kremmer, E., Carell, T., Langst, G., Leonhardt, H. (2007) DNMT1 but not its interaction with the replication machinery is required for maintenance of DNA methylation in human cells. J Cell Biol 176(5):565-571.
-
(2007)
J Cell Biol
, vol.176
, Issue.5
, pp. 565-571
-
-
Spada, F.1
Haemmer, A.2
Kuch, D.3
Rothbauer, U.4
Schermrllrh, L.5
Kremmer, E.6
Carell, T.7
Langst, G.8
Leonhardt, H.9
-
202
-
-
0026299037
-
DNA methylation patterns:an additional level of information?
-
Szyf, M. (1991) DNA methylation patterns:an additional level of information? Biochem Cell Biol 69(12):764-771.
-
(1991)
Biochem Cell Biol
, vol.69
, Issue.12
, pp. 764-771
-
-
Szyf, M.1
-
203
-
-
53349163022
-
The role of DNA hypermethylation and demethylation in cancer and cancer therapy
-
Szyf, M. (2008) The role of DNA hypermethylation and demethylation in cancer and cancer therapy. Curr Oncol 15(2):2-5.
-
(2008)
Curr Oncol
, vol.15
, Issue.2
, pp. 2-5
-
-
Szyf, M.1
-
204
-
-
65249157050
-
Epigenetics, DNA methylation and chromatin modifying drugs
-
Szyf, M. (2009) Epigenetics, DNA methylation and chromatin modifying drugs. Annu Rev Pharmacol Toxicol 49:243-263.
-
(2009)
Annu Rev Pharmacol Toxicol
, vol.49
, pp. 243-263
-
-
Szyf, M.1
-
205
-
-
0035891265
-
A histone H3 methyltransferase controls DNA methylation in Neurospora crassa
-
Tamaru, H., Selker, E. U. (2001) A histone H3 methyltransferase controls DNA methylation in Neurospora crassa. Nature 414:277-283.
-
(2001)
Nature
, vol.414
, pp. 277-283
-
-
Tamaru, H.1
Selker, E.U.2
-
206
-
-
0141706713
-
The eukaryotic Dnmt2 genes encode a new class of cytosine-5 DNA methyltransferases
-
Tang, L. Y., Reddy, M. N., Rasheva, V., Lee, T. L., Lin, M. J., Hung, M. S., Shen, C. K. (2003) The eukaryotic Dnmt2 genes encode a new class of cytosine-5 DNA methyltransferases. J Biol Chem 278(36):33613-33616.
-
(2003)
J Biol Chem
, vol.278
, Issue.36
, pp. 33613-33616
-
-
Tang, L.Y.1
Reddy, M.N.2
Rasheva, V.3
Lee, T.L.4
Lin, M.J.5
Hung, M.S.6
Shen, C.K.7
-
207
-
-
72949099235
-
Epigenetic responses to environmental change and their evolutionary implications
-
Turner, B. M. (2009) Epigenetic responses to environmental change and their evolutionary implications. Philos Trans R Soc B 364:3403-3418.
-
(2009)
Philos Trans R Soc B
, vol.364
, pp. 3403-3418
-
-
Turner, B.M.1
-
208
-
-
0029736698
-
Partial purification and characterization of human 5-methylcytosine-DNA glycosylase
-
Vairapandi, M., Duker, N. J. (1993) Partial purification and characterization of human 5-methylcytosine-DNA glycosylase. Oncogene 13:933-938.
-
(1993)
Oncogene
, vol.13
, pp. 933-938
-
-
Vairapandi, M.1
Duker, N.J.2
-
209
-
-
25444436707
-
Enzymatic DNA methylation is an epigenetic control for genetic functions of the cell
-
Vanyushin, B. F. (2005) Enzymatic DNA methylation is an epigenetic control for genetic functions of the cell. Biochemistry (Moskow), 70(5):598-611.
-
(2005)
Biochemistry (Moskow)
, vol.70
, Issue.5
, pp. 598-611
-
-
Vanyushin, B.F.1
-
210
-
-
33749019342
-
DNA methylation and epigenetics
-
Vanyushin, B. F. (2006) DNA methylation and epigenetics. Russian J Genet 42(9):985-997.
-
(2006)
Russian J Genet
, vol.42
, Issue.9
, pp. 985-997
-
-
Vanyushin, B.F.1
-
211
-
-
0035542974
-
Methyl CpG-binding proteins and transcriptional repression
-
Wade, P. A. (2001) Methyl CpG-binding proteins and transcriptional repression. Bioessays 23:1131-1137.
-
(2001)
Bioessays
, vol.23
, pp. 1131-1137
-
-
Wade, P.A.1
-
212
-
-
33644751843
-
Epigenetics:environment instructions for the genome
-
Wade, P. A., Archer, T. K. (2006) Epigenetics:environment instructions for the genome. Environ Health Perspect 114(3):A140-A141.
-
(2006)
Environ Health Perspect
, vol.114
, Issue.3
-
-
Wade, P.A.1
Archer, T.K.2
-
213
-
-
0020493818
-
Heat and alkay induced deamination of 5-methylcytosine residues in DNA
-
Wang, R. Y.-H., Kuo, K. C., Gehrke, C. W., Huang, L.-H., Ehrlich, M. (1982) Heat and alkay induced deamination of 5-methylcytosine residues in DNA. Biochim Biophis Acta (BBA)-Gene Structure and expression 697(3):371-377.
-
(1982)
Biochim Biophis Acta (BBA)-Gene Structure and expression
, vol.697
, Issue.3
, pp. 371-377
-
-
Wang, R.Y.-H.1
Kuo, K.C.2
Gehrke, C.W.3
Huang, L.-H.4
Ehrlich, M.5
-
214
-
-
0043093697
-
Transposable elements:targets for early nutritional effects in epigenetic gene regulation
-
Waterland, R. A., Jirtle, R. L. (2003) Transposable elements:targets for early nutritional effects in epigenetic gene regulation.Mol Cell Biol 23:5293-5300.
-
(2003)
Mol Cell Biol
, vol.23
, pp. 5293-5300
-
-
Waterland, R.A.1
Jirtle, R.L.2
-
215
-
-
0036094163
-
Epigenetics comes of age in toxicology
-
Watson, R. E., Goodman, J. I. (2002) Epigenetics comes of age in toxicology. Toxicol Sci 64:11-16.
-
(2002)
Toxicol Sci
, vol.64
, pp. 11-16
-
-
Watson, R.E.1
Goodman, J.I.2
-
216
-
-
0024081657
-
Cytosine methylation prevents binding to DNA of a HeLa cell transcription factor required for optimal expression of the adenovirus major late promoter
-
Watt, F., Molloy, P. L. (1988) Cytosine methylation prevents binding to DNA of a HeLa cell transcription factor required for optimal expression of the adenovirus major late promoter. Genes Dev 2(9):1136-1143.
-
(1988)
Genes Dev
, vol.2
, Issue.9
, pp. 1136-1143
-
-
Watt, F.1
Molloy, P.L.2
-
217
-
-
34047116826
-
Distribution, silencing pattern and evolutionary impact of promoter DNA methylation in the genome
-
Weber, M., Hellmann, I., Stadler, M. B., Ramos, L., Paabo, S., Rebhan, M., Schubeler, D. (2007) Distribution, silencing pattern and evolutionary impact of promoter DNA methylation in the genome. Nat Genet 39:457-464.
-
(2007)
Nat Genet
, vol.39
, pp. 457-464
-
-
Weber, M.1
Hellmann, I.2
Stadler, M.B.3
Ramos, L.4
Paabo, S.5
Rebhan, M.6
Schubeler, D.7
-
218
-
-
33847357003
-
5-Methylcytosine the fifth base of DNA:the fifth wheel on a car or a highly promising diagnistic and therapeutic target in cancer?
-
Widschwendter, M. (2007) 5-Methylcytosine the fifth base of DNA:the fifth wheel on a car or a highly promising diagnistic and therapeutic target in cancer? Disease Markers 23(1-2):1-3.
-
(2007)
Disease Markers
, vol.23
, Issue.1-2
, pp. 1-3
-
-
Widschwendter, M.1
-
219
-
-
0019957879
-
Estrogen induces a demethylation at the 5'region of the chicken citellogenin gene
-
Wilks, A. F., Cozens, P. J., Mattaj, I. W., Jost, J. P. (1982) Estrogen induces a demethylation at the 5'region of the chicken citellogenin gene. Proc Natl Acad Sci USA 79:4252-4255.
-
(1982)
Proc Natl Acad Sci USA
, vol.79
, pp. 4252-4255
-
-
Wilks, A.F.1
Cozens, P.J.2
Mattaj, I.W.3
Jost, J.P.4
-
220
-
-
55949123748
-
Type I diabetes leads to tissue-specific DNA hypomethlation in male rats
-
Williams, K. T., Garrow, T. A., Schalinske, K. L. (2008) Type I diabetes leads to tissue-specific DNA hypomethlation in male rats. J Nutr 138(11):2064-2069.
-
(2008)
J Nutr
, vol.138
, Issue.11
, pp. 2064-2069
-
-
Williams, K.T.1
Garrow, T.A.2
Schalinske, K.L.3
-
221
-
-
0033569641
-
Epigenetics:regulation through repression
-
Wolffe, A. P., Matzke, M. A. (1999) Epigenetics:regulation through repression. Science 286(5439):481-486.
-
(1999)
Science
, vol.286
, Issue.5439
, pp. 481-486
-
-
Wolffe, A.P.1
Matzke, M.A.2
-
222
-
-
0035895504
-
Human DNA repair genes
-
Wood, R. D., Mitchell, M., Sgouros, J., Lindahl, T. (2001) Human DNA repair genes. Science 291(5507):1284-1289.
-
(2001)
Science
, vol.291
, Issue.5507
, pp. 1284-1289
-
-
Wood, R.D.1
Mitchell, M.2
Sgouros, J.3
Lindahl, T.4
-
223
-
-
77956095231
-
Active DNA demethylation:many roads lead to Rome
-
Wu, C. S., Zhang, Y. (2010) Active DNA demethylation:many roads lead to Rome. Nature Rev Mol Cell Biol 11:607-620.
-
(2010)
Nature Rev Mol Cell Biol
, vol.11
, pp. 607-620
-
-
Wu, C.S.1
Zhang, Y.2
-
224
-
-
0039454340
-
Recognition and estimation of 5methylcytosine in nucleic acids
-
Wyatt, G. R. (1951) Recognition and estimation of 5methylcytosine in nucleic acids. Biochemical J. 48:581-584.
-
(1951)
Biochemical J.
, vol.48
, pp. 581-584
-
-
Wyatt, G.R.1
-
225
-
-
33845726097
-
Methylating agents and DNA repair responses:methylated bases and sources of strand breaks
-
Wyatt, M. D., Pittman, D. L. (2006) Methylating agents and DNA repair responses:methylated bases and sources of strand breaks. Chem Res Toxicol 19(12):1580-1594.
-
(2006)
Chem Res Toxicol
, vol.19
, Issue.12
, pp. 1580-1594
-
-
Wyatt, M.D.1
Pittman, D.L.2
-
226
-
-
0027977001
-
Cytosine deaminations catalyzed by DNA cytosine methyltransferases are unlikely to be the major cause of mutational hotspots at sites of cytosine methylation in Escherichia coli
-
Wyszynski, M., Gabbara, S., Bhagwat, A. (1994) Cytosine deaminations catalyzed by DNA cytosine methyltransferases are unlikely to be the major cause of mutational hotspots at sites of cytosine methylation in Escherichia coli. Proc Natl Acad Sci USA 91:1574-1578.
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 1574-1578
-
-
Wyszynski, M.1
Gabbara, S.2
Bhagwat, A.3
-
227
-
-
0033547330
-
Chromosome instability and immunodeficiency syndrome caused by mutations in a DNA methyltransferase gene
-
Xu, G. L., Bestor, T. H., Bourc'his, D., Hsieh, C. L., Tommerup, N., Bugge, M., Hulten, M., Qu, X., Russo, J. J., Viegas-Péquignot, E. (1999) Chromosome instability and immunodeficiency syndrome caused by mutations in a DNA methyltransferase gene. Nature 402:187-191.
-
(1999)
Nature
, vol.402
, pp. 187-191
-
-
Xu, G.L.1
Bestor, T.H.2
Bourc'his, D.3
Hsieh, C.L.4
Tommerup, N.5
Bugge, M.6
Hulten, M.7
Qu, X.8
Russo, J.J.9
Viegas-Péquignot, E.10
-
228
-
-
0001857355
-
Gene methylation pattern and expression
-
In:A. Razin, H. Cedar, and A. D. Riggs (eds), Springer, New York
-
Yisraeli, J., Szyf, M. (1984) Gene methylation pattern and expression. In:A. Razin, H. Cedar, and A. D. Riggs (eds) DNA Methylation:Biochemistry and Biological Significance. Springer, New York, pp. 353-378.
-
(1984)
DNA Methylation:Biochemistry and Biological Significance
, pp. 353-378
-
-
Yisraeli, J.1
Szyf, M.2
-
229
-
-
0030840954
-
Cytosine methylation and the ecology if intragenomic parasites
-
Yoder, J. A., Walsh, C. P., Bestor, T. H. (1997) Cytosine methylation and the ecology if intragenomic parasites. Trends Genet 13:335-340.
-
(1997)
Trends Genet
, vol.13
, pp. 335-340
-
-
Yoder, J.A.1
Walsh, C.P.2
Bestor, T.H.3
-
230
-
-
33750107341
-
Choline:critical role during fetal development and dietary requirements in adulthood
-
Zeisl, S. H. (2006) Choline:critical role during fetal development and dietary requirements in adulthood. Annu Rev Nutr 26:229-250.
-
(2006)
Annu Rev Nutr
, vol.26
, pp. 229-250
-
-
Zeisl, S.H.1
-
231
-
-
0032569020
-
The unmethylated state of CpG islands in mouse fibroblast depends on the poly(ADP-ribosyl)ation process
-
Zardo, G., Caiafa, P. (1998) The unmethylated state of CpG islands in mouse fibroblast depends on the poly(ADP-ribosyl)ation process. J Biol Chem 273:16517-16520.
-
(1998)
J Biol Chem
, vol.273
, pp. 16517-16520
-
-
Zardo, G.1
Caiafa, P.2
-
232
-
-
0042388012
-
A role for poly(ADP-ribosyl)ation in DNA methylation
-
Zardo, G., Reale, A., De Matteis, G., Buontempo, S., Caiafa, P. (2003) A role for poly(ADP-ribosyl)ation in DNA methylation. Biochem Cell Biol 81:197-208.
-
(2003)
Biochem Cell Biol
, vol.81
, pp. 197-208
-
-
Zardo, G.1
Reale, A.2
De Matteis, G.3
Buontempo, S.4
Caiafa, P.5
-
233
-
-
77449083293
-
Epigenetics and the environmental regulation of the genome and its function
-
Zhang, T.-H., Meaney, M. J. (2010) Epigenetics and the environmental regulation of the genome and its function. Annu Rev Psychol 61:439-466.
-
(2010)
Annu Rev Psychol
, vol.61
, pp. 439-466
-
-
Zhang, T.-H.1
Meaney, M.J.2
-
234
-
-
73349104113
-
Active DNA demethylation mediated by DNA glycosylases
-
Zhu, J.-K. (2009) Active DNA demethylation mediated by DNA glycosylases. Annu Rev Genet 43:143-166.
-
(2009)
Annu Rev Genet
, vol.43
, pp. 143-166
-
-
Zhu, J.-K.1
-
235
-
-
0034326849
-
Overexpression of 5-methylcytosine DNA glycosylase in human embryonic kidney cells EcR293 demethylates the promoter of a hormone-regulated reporter gene
-
Zhu, B., Zhenh, Y., Agliker, H., Schwarz, S., Thiry, S., Siegmann, M., Jost, J-P. (2000) Overexpression of 5-methylcytosine DNA glycosylase in human embryonic kidney cells EcR293 demethylates the promoter of a hormone-regulated reporter gene. Nature Nucleic Acids Res 28(21):4157-4165.
-
(2000)
Nature Nucleic Acids Res
, vol.28
, Issue.21
, pp. 4157-4165
-
-
Zhu, B.1
Zhenh, Y.2
Agliker, H.3
Schwarz, S.4
Thiry, S.5
Siegmann, M.6
Jost, J.-P.7
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