A histone H3 methyltransferase controls DNA methylation in Neurospora crassa

Nature

Volumn 414, Issue 6861, 2001, Pages 277-283

  Tamaru, H ^a   Selker, E U ^a  

^a UNIVERSITY OF OREGON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHROMOSOMES; MUTAGENS; PROTEINS;

TRANSPOSONS;

DNA;

DNA; GENE PRODUCT; HISTONE H3; METHYLTRANSFERASE; PROTEIN DIM2; PROTEIN DIM5; RECOMBINANT PROTEIN; UNCLASSIFIED DRUG;

DNA;

ARTICLE; DNA METHYLATION; ENZYME REGULATION; FUNGAL GENETICS; GENE SILENCING; GENETIC TRANSFORMATION; GENOME IMPRINTING; HETEROCHROMATIN; NEUROSPORA CRASSA; NONHUMAN; NONSENSE MUTATION; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN DOMAIN; SILENCER GENE; STRAIN DIFFERENCE; TRANSPOSON; X CHROMOSOME INACTIVATION;

AMINO ACID SEQUENCE; ANIMALS; CHROMOSOMAL PROTEINS, NON-HISTONE; CHROMOSOME MAPPING; CHROMOSOMES, FUNGAL; CODON, NONSENSE; DNA METHYLATION; DNA, FUNGAL; EUKARYOTIC CELLS; GENE EXPRESSION REGULATION, FUNGAL; GENE SILENCING; HETEROCHROMATIN; HISTONE-LYSINE N-METHYLTRANSFERASE; HISTONES; LYSINE; METHYLTRANSFERASES; MOLECULAR SEQUENCE DATA; NEUROSPORA CRASSA; OPEN READING FRAMES; PROTEIN STRUCTURE, TERTIARY; PROTEINS; SEQUENCE ALIGNMENT; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTORS; TRANSGENES;

NEUROSPORA; NEUROSPORA CRASSA;

EID: 0035891265     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/35104508     Document Type: Article

References (50)

1. Targeted mutation of the DNA methyltransferase gene results in embryonic lethality
2. DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development
3. Chromosome instability and immunodeficiency syndrome caused by mutations in a DNA methyltransferase gene
4. Transcriptional gene silencing mutants
5. Abnormal chromosome behavior in Neurospora mutants defective in DNA methylation
6. Dim-2 encodes a DNA-methyltransferase responsible for all known cytosine methylation in Neurospora
7. DNA methylation inhibits elongation but not initiation of transcription in Neurospora crassa
8. Epigenetic control of a transposon-inactivated gene in Neurospora is dependent on DNA methylation
9. Reduced levels and altered patterns of DNA methylation caused by mutations in Neurospora crassa
10. A methylated Neurospora 5S rRNA pseudogene contains a transposable element inactivated by RIP
11. Premeiotic instability of repeated sequences in Neurospora crassa
12. The chromo and SET domains of the Clr 4 protein are essential for silencing in fission yeast
13. The protein encoded by the Drosophila position-effect variegation suppressor gene Su(var)3- 9 combines domains of antagonistic regulators of homeotic gene complexes
14. Mutations derepressing silent centromeric domains in fission yeast disrupt chromosome segregation
15. Transgene silencing of the al-1 gene in vegetative cells of Neurospora is mediated by a cytoplasmic effector and does not depend on DNA-DNA interactions or DNA methylation
16. Re-SET-ting heterochromatin by histone methyltransferases
17. Regulation of chromatin structure by site-specific histone H3 methyltransferases
18. Role of histone H3 lysine 9 methylation in epigenetic control of heterochromatin assembly
19. Isolation and characterization of Suv39h2, a second histone H3 methyltransferase gene that displays testis-specific expression
20. The genes coding for histone H3 and H4 in Neurospora crassa are unique and contain intervening sequences
21. Heterochromatin
22. Mutation in a heterochromatin-specific chromosomal protein is associated with suppression of position-effect variegation in Drosophila melanogaster
23. Mutations in the Drosophila melanogaster gene encoding S-adenosylmethionine suppress position-effect variegation
24. Selective recognition of methylated lysine 9 on histone H3 by the HP1 chromo domain
25. Methylation of histone H3 lysine 9 creates a binding site for HP1 proteins
26. Structure of the chromosome VII centromere region in Neurospora crassa: Degenerate transposons and simple repeats
27. Eukaryotic DNA methylation as an evolutionary device
28. DNA (cytosine-5)-methyltransferases in mouse cells and tissues. Studies with a mechanism-based probe
29. ATP-dependent remodeling and acetylation as regulators of chromatin fluidity
30. Maintenance of genomic methylation requires a SWI2/SNF2-like protein
31. The language of covalent histone modifications
32. Emerging connections between DNA methylation and histone acetylation
33. Trichostatin A causes selective loss of DNA methylation in Neurospora
34. Histone deacetylase homologs regulate epigenetic inheritance of transcriptional silencing and chromosome segregation in fission yeast
35. Transient inhibition of histone deacetylation alters the structural and functional imprint at fission yeast centromeres
36. Creation of genomic methylation patterns
37. DNA methylation associated with repeat-induced point mutation in Neurospora crassa
38. Short TpA-rich segments of the zeta-eta region induce DNA methylation in Neurospora crassa
39. Dense non-symmetrical DNA methylation resulting from repeat-induced point mutation (RIP) in Neurospora
40. Kinetics of core histones in living human cells. Little exchange of h3 and h4 and some rapid exchange of h2b
41. The phenomenon of position effect
42. Position effect variegation at fission yeast centromeres
43. Chromosomal inheritance of epigenetic states in fission yeast during mitosis and meiosis
44. SET domain-containing protein, G9a, is a novel lysine-preferring mammalian histone methyltransferase with hyperactivity and specific selectivity to lysines 9 and 27 of histone H3
45. Requirement of Chromomethylase 3 for maintenance of CpXpG methylation
46. Improved plasmids for gene targeting at the his-3 locus of Neurospora crassa by electroporation
47. Cloning and characterization of the gene for β-tubulin from a benomyl-resistant mutant of Neurospora crassa and its use as a dominant selectable marker
48. Cytosine methylation associated with repeat-induced point mutation causes epigenetic gene silencing in Neurospora crassa
49. Non-CpG methylation is prevalent in embryonic stem cells and may be mediated by DNA methyltransferase 3a