How epigenetics integrates nuclear functions. Workshop on Epigenetics and Chromatin: Transcriptional Regulation and Beyond

EMBO Reports

Volumn 6, Issue 7, 2005, Pages 624-628

  Esteller, Manel ^a   Almouzni, Geneviève ^b  

^a Centro Nacional de Investigaciones Oncológicas   (Spain)

^b INSTITUT CURIE   (France)

Author keywords

Chromatin; DNA methylation; Histone modification; Insulator; Nucleosome

Indexed keywords

ARGININE; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN BINDING PROTEIN; DNA; HISTONE; HISTONE ACETYLTRANSFERASE; HISTONE DEACETYLASE; HYBRID PROTEIN; LYSINE; RETINOIC ACID RECEPTOR; SERINE; ZINC FINGER PROTEIN;

ACETYLATION; CANCER CELL; CARCINOGENESIS; CELL COMPARTMENTALIZATION; CELL FUNCTION; CELL NUCLEUS; CHROMATIN; CHROMATIN ASSEMBLY AND DISASSEMBLY; CHROMATIN STRUCTURE; CONFERENCE PAPER; DNA METHYLATION; DNA MODIFICATION; EPIGENETICS; GENE EXPRESSION; GENE MUTATION; GENE SILENCING; GENETIC CODE; GENETIC TRANSCRIPTION; HUMAN; LEUKEMOGENESIS; MALIGNANT TRANSFORMATION; METHYLATION; NUCLEOSOME; PRIORITY JOURNAL; PROMYELOCYTIC LEUKEMIA; PROTEIN MODIFICATION; PROTEIN PHOSPHORYLATION; PROTEIN PROCESSING; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION; WORKSHOP;

CELL NUCLEUS; CHROMATIN; CHROMATIN ASSEMBLY AND DISASSEMBLY; EPIGENESIS, GENETIC; GENE EXPRESSION REGULATION; HUMANS; NEOPLASMS; TRANSCRIPTION, GENETIC;

EID: 23744457857     PISSN: 1469221X     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.embor.7400456     Document Type: Conference Paper

References (24)

1. Bird AP, Wolffe AP (1999) Methylation-induced repression - belts, braces, and chromatin. Cell 99: 451-454
2. Chen WY, Zeng X, Carter MG, Morrell CN, Chiu Yen RW, Esteller M, Watkins DN, Herman JG, Mankowski JL, Baylin SB (2003) Heterozygous disruption of Hic1 predisposes mice to a gender-dependent spectrum of malignant tumors. Nat Genet 33: 197-202
3. Cuthbert GL et al (2004) Histone deimination antagonizes arginine methylation. Cell 118: 545-553
4. Emre NC et al (2005) Maintenance of low histone ubiquitylation by Ubp10 correlates with telomere-proximal Sir2 association and gene silencing. Mol Cell 17: 585-594
5. Espada J, Ballestar E, Fraga MF, Villar-Garea A, Juarranz A, Stockert JC, Robertson KD, Fuks F, Esteller M (2004) Human DNA methyltransferase 1 is required for maintenance of the histone H3 modification pattern. J Biol Chem 279: 37175-37184
6. Fraga MF et al (2005) Loss of acetylation at Lys16 and trimethylation at Lys20 of histone H4 is a common hallmark of human cancer. Nat Genet 37: 391-400
7. Gonzalo S et al (2005) Role of the RB1 family in stabilizing histone methylation at constitutive heterochromatin. Nat Cell Biol 7: 420-428
8. Henry KW, Wyce A, Lo WS, Duggan LJ, Emre NC, Kao CF, Pillus L, Shilatifard A, Osley MA, Berger SL (2003) Transcriptional activation via sequential histone H2B ubiquitylation and deubiquitylation, mediated by SAGA-associated Ubp8. Genes Dev 17: 2648-2663
9. Insinga A, Monestiroli S, Ronzoni S, Gelmetti V, Marchesi F, Viale A, Altucci L, Nervi C, Minucci S, Pelicci PG (2005) Inhibitors of histone deacetylases induce tumor-selective apoptosis through activation of the death receptor pathway. Nat Med 11: 71-76
10. Lee KK, Florens L, Swanson SK, Washburn MP, Workman JL (2005) The deubiquitylation activity of Ubp8 is dependent upon Sgf11 and its association with the SAGA complex. Mol Cell Biol 25: 1173-1182
11. Lewis A, Mitsuya K, Umlauf D, Smith F, Dean W, Walter J, Higgins M, Feil R, Reik W (2004) Imprinting on distal chromosome 7 in the placenta involves repressive histone methylation independent of DNA methylation. Nat Genet 36: 1291-1295
12. Martens JH, O'Sullivan RJ, Braunschweig U, Opravil S, Radolf M, Steinlein P, Jenuwein T (2005) The profile of repeat-associated histone lysine methylation states in the mouse epigenome. EMBO J 24: 800-812
13. Mason PB, Struhl K (2005) Distinction and relationship between elongation rate and processivity of RNA polymerase II in vivo. Mol Cell 17: 831-840
14. McKittrick E, Gafken PR, Ahmad K, Henikoff S (2004) Histone H3.3 is enriched in covalent modifications associated with active chromatin. Proc Natl Acad Sci USA 101: 1525-1530
15. Murrell A, Heeson S, Reik W (2004) Interaction between differentially methylated regions partitions the imprinted genes Igf2 and H19 into parent-specific chromatin loops. Nat Genet 36: 889-893
16. Peterson CL, Laniel MA (2004) Histones and histone modifications. Curr Biol 14: R546-R551
17. Quivy JP, Roche D, Kirschner D, Tagami H, Nakatani Y, Almouzni G (2004) A CAF-1 dependent pool of HP1 during heterochromatin duplication. EMBO J 23: 3516-3526
18. Reik W, Lewis A (2005) Co-evolution of X-chromosome inactivation and imprinting in mammals. Nat Rev Genet 6: 403-410
19. Shi Y, Lan F, Matson C, Mulligan P, Whetstine JR, Cole PA, Casero RA, Shi Y (2004) Histone demethylation mediated by the nuclear amine oxidase homolog LSD1. Cell 119: 941-953
20. Strahl BD, Allis CD (2000) The language of covalent histone modifications. Nature 403: 41-45
21. Turner BM (2000) Histone acetylation and an epigenetic code. Bioessays 22: 836-845
22. Turner BM (2005) Reading signals on the nucleosome with a new nomenclature for modified histones. Nat Struct Mol Biol 12: 110-112
23. Vicent GP, Nacht AS, Smith CL, Peterson CL, Dimitrov S, Beato M (2004) DNA instructed displacement of histones H2A and H2B at an inducible promoter. Mol Cell 16: 439-452
24. Wang Y et al (2004) Human PAD4 regulates histone arginine methylation levels via demethylimination. Science 306: 279-283