-
1
-
-
80055064689
-
Toll-8/Tollo negatively regulates antimicrobial response in the Drosophila respiratory epithelium
-
Akhouayri I., Turc C., Royet J., Charroux B. Toll-8/Tollo negatively regulates antimicrobial response in the Drosophila respiratory epithelium. PLoS Pathog. 2011, 7:e1002319.
-
(2011)
PLoS Pathog.
, vol.7
-
-
Akhouayri, I.1
Turc, C.2
Royet, J.3
Charroux, B.4
-
2
-
-
0021603716
-
Information for the dorsal-ventral pattern of the Drosophila embryo is stored as maternal mRNA
-
Anderson K.V., Nusslein V.C. Information for the dorsal-ventral pattern of the Drosophila embryo is stored as maternal mRNA. Nature 1984, 311:223-227.
-
(1984)
Nature
, vol.311
, pp. 223-227
-
-
Anderson, K.V.1
Nusslein, V.C.2
-
3
-
-
43149106745
-
NF-kappaB/rel-mediated regulation of the neural fate in Drosophila
-
Ayyar S., Pistillo D., Calleja M., Brookfield A., Gittins K., Goldstone C., Simpson P. NF-kappaB/rel-mediated regulation of the neural fate in Drosophila. PLoS One 2007, 2:e1178.
-
(2007)
PLoS One
, vol.2
-
-
Ayyar, S.1
Pistillo, D.2
Calleja, M.3
Brookfield, A.4
Gittins, K.5
Goldstone, C.6
Simpson, P.7
-
4
-
-
0029730738
-
A conserved signaling pathway: the Drosophila Toll-dorsal pathway
-
Belvin M.P., Anderson K.V. A conserved signaling pathway: the Drosophila Toll-dorsal pathway. Annu. Rev. Cell Dev. Biol. 1996, 12:393-416.
-
(1996)
Annu. Rev. Cell Dev. Biol.
, vol.12
, pp. 393-416
-
-
Belvin, M.P.1
Anderson, K.V.2
-
6
-
-
9244251126
-
Function of the Drosophila pattern-recognition receptor PGRP-SD in the detection of Gram-positive bacteria
-
Bischoff V., Vignal C., Boneca I.G., Michel T., Hoffmann J.A., Royet J. Function of the Drosophila pattern-recognition receptor PGRP-SD in the detection of Gram-positive bacteria. Nat. Immunol. 2004, 5:1175-1180.
-
(2004)
Nat. Immunol.
, vol.5
, pp. 1175-1180
-
-
Bischoff, V.1
Vignal, C.2
Boneca, I.G.3
Michel, T.4
Hoffmann, J.A.5
Royet, J.6
-
7
-
-
2442715852
-
Drosophila: the genetics of innate immune recognition and response
-
Brennan C.A., Anderson K.V. Drosophila: the genetics of innate immune recognition and response. Annu. Rev. Immunol. 2004, 22:457-483.
-
(2004)
Annu. Rev. Immunol.
, vol.22
, pp. 457-483
-
-
Brennan, C.A.1
Anderson, K.V.2
-
8
-
-
68149091551
-
A single modular serine protease integrates signals from pattern-recognition receptors upstream of the Drosophila Toll pathway
-
Buchon N., Poidevin M., Kwon H.M., Guillou A., Sottas V., Lee B.L., Lemaitre B. A single modular serine protease integrates signals from pattern-recognition receptors upstream of the Drosophila Toll pathway. Proc. Natl. Acad. Sci. USA 2009, 106:12442-12447.
-
(2009)
Proc. Natl. Acad. Sci. USA
, vol.106
, pp. 12442-12447
-
-
Buchon, N.1
Poidevin, M.2
Kwon, H.M.3
Guillou, A.4
Sottas, V.5
Lee, B.L.6
Lemaitre, B.7
-
9
-
-
84874023911
-
Dynamic evolution of Toll-like receptor multigene families in echinoderms
-
Buckley K.M., Rast J.P. Dynamic evolution of Toll-like receptor multigene families in echinoderms. Front. Immunol. 2012, 3:136.
-
(2012)
Front. Immunol.
, vol.3
, pp. 136
-
-
Buckley, K.M.1
Rast, J.P.2
-
10
-
-
34748841977
-
Extraordinary diversity among members of the large gene family, 185/333, from the purple sea urchin, Strongylocentrotus purpuratus
-
Buckley K.M., Smith L.C. Extraordinary diversity among members of the large gene family, 185/333, from the purple sea urchin, Strongylocentrotus purpuratus. BMC Mol. Biol. 2007, 8:68.
-
(2007)
BMC Mol. Biol.
, vol.8
, pp. 68
-
-
Buckley, K.M.1
Smith, L.C.2
-
11
-
-
34548071028
-
A kappaB sequence code for pathway-specific innate immune responses
-
Busse M.S., Arnold C.P., Towb P., Katrivesis J., Wasserman S.A. A kappaB sequence code for pathway-specific innate immune responses. EMBO J. 2007, 26:3826-3835.
-
(2007)
EMBO J.
, vol.26
, pp. 3826-3835
-
-
Busse, M.S.1
Arnold, C.P.2
Towb, P.3
Katrivesis, J.4
Wasserman, S.A.5
-
12
-
-
33748871187
-
The human adaptor SARM negatively regulates adaptor protein TRIF-dependent Toll-like receptor signaling
-
Carty M., Goodbody R., Schroder M., Stack J., Moynagh P.N., Bowie A.G. The human adaptor SARM negatively regulates adaptor protein TRIF-dependent Toll-like receptor signaling. Nat. Immunol. 2006, 7:1074-1081.
-
(2006)
Nat. Immunol.
, vol.7
, pp. 1074-1081
-
-
Carty, M.1
Goodbody, R.2
Schroder, M.3
Stack, J.4
Moynagh, P.N.5
Bowie, A.G.6
-
13
-
-
77957221590
-
Proteolytic cascades and their involvement in invertebrate immunity
-
Cerenius L., Kawabata S., Lee B.L., Nonaka M., Soderhall K. Proteolytic cascades and their involvement in invertebrate immunity. Trends Biochem. Sci. 2010, 35:575-583.
-
(2010)
Trends Biochem. Sci.
, vol.35
, pp. 575-583
-
-
Cerenius, L.1
Kawabata, S.2
Lee, B.L.3
Nonaka, M.4
Soderhall, K.5
-
14
-
-
0024965999
-
The role of Easter, an apparent serine protease, in organizing the dorsal-ventral pattern of the Drosophila embryo
-
Chasan R., Anderson K.V. The role of Easter, an apparent serine protease, in organizing the dorsal-ventral pattern of the Drosophila embryo. Cell 1989, 56:391-400.
-
(1989)
Cell
, vol.56
, pp. 391-400
-
-
Chasan, R.1
Anderson, K.V.2
-
15
-
-
84875236362
-
Regulation of NF-kappaB by ubiquitination
-
Chen J., Chen Z.J. Regulation of NF-kappaB by ubiquitination. Curr. Opin. Immunol. 2013, 25:4-12.
-
(2013)
Curr. Opin. Immunol.
, vol.25
, pp. 4-12
-
-
Chen, J.1
Chen, Z.J.2
-
16
-
-
0037066464
-
Requirement for a peptidoglycan recognition protein (PGRP) in relish activation and antibacterial immune responses in Drosophila
-
Choe K.M., Werner T., Stoven S., Hultmark D., Anderson K.V. Requirement for a peptidoglycan recognition protein (PGRP) in relish activation and antibacterial immune responses in Drosophila. Science 2002, 296:359-362.
-
(2002)
Science
, vol.296
, pp. 359-362
-
-
Choe, K.M.1
Werner, T.2
Stoven, S.3
Hultmark, D.4
Anderson, K.V.5
-
17
-
-
12844279852
-
Drosophila peptidoglycan recognition protein LC (PGRP-LC) acts as a signal-transducing innate immune receptor
-
Choe K.M., Lee H., Anderson K.V. Drosophila peptidoglycan recognition protein LC (PGRP-LC) acts as a signal-transducing innate immune receptor. Proc. Natl. Acad. Sci. USA 2005, 102:1122-1126.
-
(2005)
Proc. Natl. Acad. Sci. USA
, vol.102
, pp. 1122-1126
-
-
Choe, K.M.1
Lee, H.2
Anderson, K.V.3
-
18
-
-
12144283454
-
A Toll-interleukin 1 repeat protein at the synapse specifies asymmetric odorant receptor expression via ASK1 MAPKKK signaling
-
Chuang C.F., Bargmann C.I. A Toll-interleukin 1 repeat protein at the synapse specifies asymmetric odorant receptor expression via ASK1 MAPKKK signaling. Gene Dev. 2005, 19:270-281.
-
(2005)
Gene Dev.
, vol.19
, pp. 270-281
-
-
Chuang, C.F.1
Bargmann, C.I.2
-
19
-
-
2442664007
-
TLR-independent control of innate immunity in Caenorhabditis elegans by the TIR domain adaptor protein TIR-1, an ortholog of human SARM
-
Couillault C., Pujol N., Reboul J., Sabatier L., Guichou J.F., Kohara Y., Ewbank J.J. TLR-independent control of innate immunity in Caenorhabditis elegans by the TIR domain adaptor protein TIR-1, an ortholog of human SARM. Nat. Immunol. 2004, 5:488-494.
-
(2004)
Nat. Immunol.
, vol.5
, pp. 488-494
-
-
Couillault, C.1
Pujol, N.2
Reboul, J.3
Sabatier, L.4
Guichou, J.F.5
Kohara, Y.6
Ewbank, J.J.7
-
20
-
-
0035940514
-
Genome-wide analysis of the Drosophila immune response by using oligonucleotide microarrays
-
De Gregorio E., Spellman P.T., Rubin G.M., Lemaitre B. Genome-wide analysis of the Drosophila immune response by using oligonucleotide microarrays. Proc. Natl. Acad. Sci. USA 2001, 98:12590-12595.
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 12590-12595
-
-
De Gregorio, E.1
Spellman, P.T.2
Rubin, G.M.3
Lemaitre, B.4
-
21
-
-
0037013856
-
The Toll and Imd pathways are the major regulators of the immune response in Drosophila
-
De Gregorio E., Spellman P.T., Tzou P., Rubin G.M., Lemaitre B. The Toll and Imd pathways are the major regulators of the immune response in Drosophila. EMBO J. 2002, 21:2568-2579.
-
(2002)
EMBO J.
, vol.21
, pp. 2568-2579
-
-
De Gregorio, E.1
Spellman, P.T.2
Tzou, P.3
Rubin, G.M.4
Lemaitre, B.5
-
22
-
-
56349115840
-
The DExD/H-box helicase Dicer-2 mediates the induction of antiviral activity in Drosophila
-
Deddouche S., Matt N., Budd A., Mueller S., Kemp C., Galiana-Arnoux D., Dostert C., Antoniewski C., Hoffmann J.A., Imler J.L. The DExD/H-box helicase Dicer-2 mediates the induction of antiviral activity in Drosophila. Nat. Immunol. 2008, 9:1425-1432.
-
(2008)
Nat. Immunol.
, vol.9
, pp. 1425-1432
-
-
Deddouche, S.1
Matt, N.2
Budd, A.3
Mueller, S.4
Kemp, C.5
Galiana-Arnoux, D.6
Dostert, C.7
Antoniewski, C.8
Hoffmann, J.A.9
Imler, J.L.10
-
23
-
-
0032033030
-
Proteolytic processing of the Drosophila Spatzle protein by Easter generates a dimeric NGF-like molecule with ventralising activity
-
DeLotto Y., DeLotto R. Proteolytic processing of the Drosophila Spatzle protein by Easter generates a dimeric NGF-like molecule with ventralising activity. Mech. Dev. 1998, 72:141-148.
-
(1998)
Mech. Dev.
, vol.72
, pp. 141-148
-
-
DeLotto, Y.1
DeLotto, R.2
-
24
-
-
0036230096
-
Screening the fruit fly immune system.
-
3, REVIEWS1010.
-
Dionne, M.S., Schneider, D.S., 2002. Screening the fruit fly immune system. Genome Biol. 3, REVIEWS1010.
-
(2002)
Genome Biol.
-
-
Dionne, M.S.1
Schneider, D.S.2
-
25
-
-
24944485547
-
The Jak-STAT signaling pathway is required but not sufficient for the antiviral response of Drosophila
-
Dostert C., Jouanguy E., Irving P., Troxler L., Galiana-Arnoux D., Hetru C., Hoffmann J.A., Imler J.L. The Jak-STAT signaling pathway is required but not sufficient for the antiviral response of Drosophila. Nat. Immunol. 2005, 6:946-953.
-
(2005)
Nat. Immunol.
, vol.6
, pp. 946-953
-
-
Dostert, C.1
Jouanguy, E.2
Irving, P.3
Troxler, L.4
Galiana-Arnoux, D.5
Hetru, C.6
Hoffmann, J.A.7
Imler, J.L.8
-
26
-
-
0031126767
-
The dorsoventral signal transduction pathway and the Rel-like transcription factors in Drosophila
-
Drier E.A., Steward R. The dorsoventral signal transduction pathway and the Rel-like transcription factors in Drosophila. Semin. Cancer Biol. 1997, 8:83-92.
-
(1997)
Semin. Cancer Biol.
, vol.8
, pp. 83-92
-
-
Drier, E.A.1
Steward, R.2
-
27
-
-
52549093726
-
Sensing of 'danger signals' and pathogen-associated molecular patterns defines binary signaling pathways 'upstream' of Toll
-
El Chamy L., Leclerc V., Caldelari I., Reichhart J.M. Sensing of 'danger signals' and pathogen-associated molecular patterns defines binary signaling pathways 'upstream' of Toll. Nat. Immunol. 2008, 9:1165-1170.
-
(2008)
Nat. Immunol.
, vol.9
, pp. 1165-1170
-
-
El Chamy, L.1
Leclerc, V.2
Caldelari, I.3
Reichhart, J.M.4
-
28
-
-
67649858793
-
Two roles for the Drosophila IKK complex in the activation of Relish and the induction of antimicrobial peptide genes
-
Erturk-Hasdemir D., Broemer M., Leulier F., Lane W.S., Paquette N., Hwang D., Kim C.H., Stoven S., Meier P., Silverman N. Two roles for the Drosophila IKK complex in the activation of Relish and the induction of antimicrobial peptide genes. Proc. Natl. Acad. Sci. USA 2009, 106:9779-9784.
-
(2009)
Proc. Natl. Acad. Sci. USA
, vol.106
, pp. 9779-9784
-
-
Erturk-Hasdemir, D.1
Broemer, M.2
Leulier, F.3
Lane, W.S.4
Paquette, N.5
Hwang, D.6
Kim, C.H.7
Stoven, S.8
Meier, P.9
Silverman, N.10
-
29
-
-
0028587829
-
Insect immunity. Septic injury of Drosophila induces the synthesis of a potent antifungal peptide with sequence homology to plant antifungal peptides
-
Fehlbaum P., Bulet P., Michaut L., Lagueux M., Broekaert W.F., Hetru C., Hoffmann J.A. Insect immunity. Septic injury of Drosophila induces the synthesis of a potent antifungal peptide with sequence homology to plant antifungal peptides. J. Biol. Chem. 1994, 269:33159-33163.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 33159-33163
-
-
Fehlbaum, P.1
Bulet, P.2
Michaut, L.3
Lagueux, M.4
Broekaert, W.F.5
Hetru, C.6
Hoffmann, J.A.7
-
30
-
-
0032473360
-
A drosomycin-GFP reporter transgene reveals a local immune response in Drosophila that is not dependent on the Toll pathway
-
Ferrandon D., Jung A.C., Criqui M., Lemaitre B., Uttenweiler-Joseph S., Michaut L., Reichhart J., Hoffmann J.A. A drosomycin-GFP reporter transgene reveals a local immune response in Drosophila that is not dependent on the Toll pathway. EMBO J. 1998, 17:1217-1227.
-
(1998)
EMBO J.
, vol.17
, pp. 1217-1227
-
-
Ferrandon, D.1
Jung, A.C.2
Criqui, M.3
Lemaitre, B.4
Uttenweiler-Joseph, S.5
Michaut, L.6
Reichhart, J.7
Hoffmann, J.A.8
-
31
-
-
35549006674
-
The Drosophila systemic immune response: sensing and signaling during bacterial and fungal infections
-
Ferrandon D., Imler J.L., Hetru C., Hoffmann J.A. The Drosophila systemic immune response: sensing and signaling during bacterial and fungal infections. Nat. Rev. Immunol. 2007, 7:862-874.
-
(2007)
Nat. Rev. Immunol.
, vol.7
, pp. 862-874
-
-
Ferrandon, D.1
Imler, J.L.2
Hetru, C.3
Hoffmann, J.A.4
-
32
-
-
79960379686
-
Spn1 regulates the GNBP3-dependent Toll signaling pathway in Drosophila melanogaster
-
Fullaondo A., Garcia-Sanchez S., Sanz-Parra A., Recio E., Lee S.Y., Gubb D. Spn1 regulates the GNBP3-dependent Toll signaling pathway in Drosophila melanogaster. Mol. Cell. Biol. 2011, 31:2960-2972.
-
(2011)
Mol. Cell. Biol.
, vol.31
, pp. 2960-2972
-
-
Fullaondo, A.1
Garcia-Sanchez, S.2
Sanz-Parra, A.3
Recio, E.4
Lee, S.Y.5
Gubb, D.6
-
33
-
-
79952757149
-
NF-kappaB/Rel proteins and the humoral immune responses of Drosophila melanogaster
-
Ganesan S., Aggarwal K., Paquette N., Silverman N. NF-kappaB/Rel proteins and the humoral immune responses of Drosophila melanogaster. Curr. Top. Microbiol. Immunol. 2011, 349:25-60.
-
(2011)
Curr. Top. Microbiol. Immunol.
, vol.349
, pp. 25-60
-
-
Ganesan, S.1
Aggarwal, K.2
Paquette, N.3
Silverman, N.4
-
34
-
-
47249114405
-
Structural insight into the mechanism of activation of the Toll receptor by the dimeric ligand Spatzle
-
Gangloff M., Murali A., Xiong J., Arnot C.J., Weber A.N., Sandercock A.M., Robinson C.V., Sarisky R., Holzenburg A., Kao C., Gay N.J. Structural insight into the mechanism of activation of the Toll receptor by the dimeric ligand Spatzle. J. Biol. Chem. 2008, 283:14629-14635.
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 14629-14635
-
-
Gangloff, M.1
Murali, A.2
Xiong, J.3
Arnot, C.J.4
Weber, A.N.5
Sandercock, A.M.6
Robinson, C.V.7
Sarisky, R.8
Holzenburg, A.9
Kao, C.10
Gay, N.J.11
-
35
-
-
84872153469
-
Functional insights from the crystal structure of the N-terminal domain of the prototypical Toll receptor
-
Gangloff M., Arnot C.J., Lewis M., Gay N.J. Functional insights from the crystal structure of the N-terminal domain of the prototypical Toll receptor. Structure 2013, 21:143-153.
-
(2013)
Structure
, vol.21
, pp. 143-153
-
-
Gangloff, M.1
Arnot, C.J.2
Lewis, M.3
Gay, N.J.4
-
36
-
-
18044400563
-
Drosophila immune deficiency (IMD) is a death domain protein that activates antibacterial defense and can promote apoptosis
-
Georgel P., Naitza S., Kappler C., Ferrandon D., Zachary D., Swimmer C., Kopczynski C., Duyk G., Reichhart J.M., Hoffmann J.A. Drosophila immune deficiency (IMD) is a death domain protein that activates antibacterial defense and can promote apoptosis. Dev. Cell 2001, 1:503-514.
-
(2001)
Dev. Cell
, vol.1
, pp. 503-514
-
-
Georgel, P.1
Naitza, S.2
Kappler, C.3
Ferrandon, D.4
Zachary, D.5
Swimmer, C.6
Kopczynski, C.7
Duyk, G.8
Reichhart, J.M.9
Hoffmann, J.A.10
-
37
-
-
0345731463
-
Dual activation of the Drosophila Toll pathway by two pattern recognition receptors
-
Gobert V., Gottar M., Matskevich A.A., Rutschmann S., Royet J., Belvin M., Hoffmann J.A., Ferrandon D. Dual activation of the Drosophila Toll pathway by two pattern recognition receptors. Science 2003, 302:2126-2130.
-
(2003)
Science
, vol.302
, pp. 2126-2130
-
-
Gobert, V.1
Gottar, M.2
Matskevich, A.A.3
Rutschmann, S.4
Royet, J.5
Belvin, M.6
Hoffmann, J.A.7
Ferrandon, D.8
-
38
-
-
33845666959
-
Dual detection of fungal infections in Drosophila via recognition of glucans and sensing of virulence factors
-
Gottar M., Gobert V., Matskevich A.A., Reichhart J.M., Wang C., Butt T.M., Belvin M., Hoffmann J.A., Ferrandon D. Dual detection of fungal infections in Drosophila via recognition of glucans and sensing of virulence factors. Cell 2006, 127:1425-1437.
-
(2006)
Cell
, vol.127
, pp. 1425-1437
-
-
Gottar, M.1
Gobert, V.2
Matskevich, A.A.3
Reichhart, J.M.4
Wang, C.5
Butt, T.M.6
Belvin, M.7
Hoffmann, J.A.8
Ferrandon, D.9
-
39
-
-
65249150241
-
Innate immunity in Drosophila: pathogens and pathways
-
Govind S. Innate immunity in Drosophila: pathogens and pathways. Insect Sci. 2008, 15:29-43.
-
(2008)
Insect Sci.
, vol.15
, pp. 29-43
-
-
Govind, S.1
-
40
-
-
0032126846
-
The Toll pathway is required in the epidermis for muscle development in the Drosophila embryo
-
Halfon M.S., Keshishian H. The Toll pathway is required in the epidermis for muscle development in the Drosophila embryo. Dev. Biol. 1998, 199:164-174.
-
(1998)
Dev. Biol.
, vol.199
, pp. 164-174
-
-
Halfon, M.S.1
Keshishian, H.2
-
41
-
-
0033597935
-
Interaction and specificity of Rel-related proteins in regulating Drosophila immunity gene expression
-
Han Z.S., Ip Y.T. Interaction and specificity of Rel-related proteins in regulating Drosophila immunity gene expression. J. Biol. Chem. 1999, 274:21355-21361.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 21355-21361
-
-
Han, Z.S.1
Ip, Y.T.2
-
42
-
-
34548569929
-
NF-kappaB, IkappaB, and IRAK control glutamate receptor density at the Drosophila NMJ
-
Heckscher E.S., Fetter R.D., Marek K.W., Albin S.D., Davis G.W. NF-kappaB, IkappaB, and IRAK control glutamate receptor density at the Drosophila NMJ. Neuron 2007, 55:859-873.
-
(2007)
Neuron
, vol.55
, pp. 859-873
-
-
Heckscher, E.S.1
Fetter, R.D.2
Marek, K.W.3
Albin, S.D.4
Davis, G.W.5
-
43
-
-
2442670518
-
Differential activation of the NF-kappaB-like factors Relish and Dif in Drosophila melanogaster by fungi and Gram-positive bacteria.
-
Hedengren-Olcott, M., Olcott, M.C., Mooney, D.T., Ekengren, S., Geller, B.L., Taylor, B.J., 2004. Differential activation of the NF-kappaB-like factors Relish and Dif in Drosophila melanogaster by fungi and Gram-positive bacteria. J. Biol. Chem. 279, 21121-21127.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 21121-21127
-
-
Hedengren-Olcott, M.1
Olcott, M.C.2
Mooney, D.T.3
Ekengren, S.4
Geller, B.L.5
Taylor, B.J.6
-
44
-
-
0035940499
-
Drosophila MyD88 is an adapter in the Toll signaling pathway
-
Horng T., Medzhitov R. Drosophila MyD88 is an adapter in the Toll signaling pathway. Proc. Natl. Acad. Sci. USA 2001, 98:12654-12658.
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 12654-12658
-
-
Horng, T.1
Medzhitov, R.2
-
45
-
-
77952382637
-
Endocytic pathway is required for Drosophila Toll innate immune signaling
-
Huang H.R., Chen Z.J., Kunes S., Chang G.D., Maniatis T. Endocytic pathway is required for Drosophila Toll innate immune signaling. Proc. Natl. Acad. Sci. USA 2010, 107:8322-8327.
-
(2010)
Proc. Natl. Acad. Sci. USA
, vol.107
, pp. 8322-8327
-
-
Huang, H.R.1
Chen, Z.J.2
Kunes, S.3
Chang, G.D.4
Maniatis, T.5
-
46
-
-
8344288192
-
Toll-dependent and Toll-independent immune responses in Drosophila
-
Imler J.L., Ferrandon D., Royet J., Reichhart J.M., Hetru C., Hoffmann J.A. Toll-dependent and Toll-independent immune responses in Drosophila. J. Endotoxin Res. 2004, 10:241-246.
-
(2004)
J. Endotoxin Res.
, vol.10
, pp. 241-246
-
-
Imler, J.L.1
Ferrandon, D.2
Royet, J.3
Reichhart, J.M.4
Hetru, C.5
Hoffmann, J.A.6
-
47
-
-
0026089246
-
The dorsal morphogen is a sequence-specific DNA-binding protein that interacts with a long-range repression element in Drosophila
-
Ip Y.T., Kraut R., Levine M., Rushlow C.A. The dorsal morphogen is a sequence-specific DNA-binding protein that interacts with a long-range repression element in Drosophila. Cell 1991, 64:439-446.
-
(1991)
Cell
, vol.64
, pp. 439-446
-
-
Ip, Y.T.1
Kraut, R.2
Levine, M.3
Rushlow, C.A.4
-
48
-
-
0027443688
-
Dif, a dorsal-related gene that mediates an immune response in Drosophila
-
Ip Y.T., Reach M., Engstrom Y., Kadalayil L., Cai H., Gonzalez-Crespo S., Tatei K., Levine M. Dif, a dorsal-related gene that mediates an immune response in Drosophila. Cell 1993, 75:753-763.
-
(1993)
Cell
, vol.75
, pp. 753-763
-
-
Ip, Y.T.1
Reach, M.2
Engstrom, Y.3
Kadalayil, L.4
Cai, H.5
Gonzalez-Crespo, S.6
Tatei, K.7
Levine, M.8
-
49
-
-
0035909905
-
A genome-wide analysis of immune responses in Drosophila
-
Irving P., Troxler L., Heuer T.S., Belvin M., Kopczynski C., Reichhart J.M., Hoffmann J.A., Hetru C. A genome-wide analysis of immune responses in Drosophila. Proc. Natl. Acad. Sci. USA 2001, 98:15119-15124.
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 15119-15124
-
-
Irving, P.1
Troxler, L.2
Heuer, T.S.3
Belvin, M.4
Kopczynski, C.5
Reichhart, J.M.6
Hoffmann, J.A.7
Hetru, C.8
-
50
-
-
0026791975
-
The immune system evolved to discriminate infectious non-self from noninfectious self
-
Janeway C.A. The immune system evolved to discriminate infectious non-self from noninfectious self. Immunol. Today 1992, 13:11-16.
-
(1992)
Immunol. Today
, vol.13
, pp. 11-16
-
-
Janeway, C.A.1
-
51
-
-
29744438644
-
A Spatzle-processing enzyme required for toll signaling activation in Drosophila innate immunity
-
Jang I.H., Chosa N., Kim S.H., Nam H.J., Lemaitre B., Ochiai M., Kambris Z., Brun S., Hashimoto C., Ashida M., Brey P.T., Lee W.J. A Spatzle-processing enzyme required for toll signaling activation in Drosophila innate immunity. Dev. Cell 2006, 10:45-55.
-
(2006)
Dev. Cell
, vol.10
, pp. 45-55
-
-
Jang, I.H.1
Chosa, N.2
Kim, S.H.3
Nam, H.J.4
Lemaitre, B.5
Ochiai, M.6
Kambris, Z.7
Brun, S.8
Hashimoto, C.9
Ashida, M.10
Brey, P.T.11
Lee, W.J.12
-
52
-
-
84855266350
-
Duox, Flotillin-2, and Src42A are required to activate or delimit the spread of the transcriptional response to epidermal wounds in Drosophila
-
Juarez M.T., Patterson R.A., Sandoval-Guillen E., McGinnis W. Duox, Flotillin-2, and Src42A are required to activate or delimit the spread of the transcriptional response to epidermal wounds in Drosophila. PLoS Genet. 2011, 7:e1002424.
-
(2011)
PLoS Genet.
, vol.7
-
-
Juarez, M.T.1
Patterson, R.A.2
Sandoval-Guillen, E.3
McGinnis, W.4
-
53
-
-
33646908228
-
Phosphoinositide-mediated adaptor recruitment controls Toll-like receptor signaling
-
Kagan J.C., Medzhitov R. Phosphoinositide-mediated adaptor recruitment controls Toll-like receptor signaling. Cell 2006, 125:943-955.
-
(2006)
Cell
, vol.125
, pp. 943-955
-
-
Kagan, J.C.1
Medzhitov, R.2
-
54
-
-
33646037067
-
Drosophila immunity: a large-scale in vivo RNAi screen identifies five serine proteases required for Toll activation
-
Kambris Z., Brun S., Jang I.H., Nam H.J., Romeo Y., Takahashi K., Lee W.J., Ueda R., Lemaitre B. Drosophila immunity: a large-scale in vivo RNAi screen identifies five serine proteases required for Toll activation. Curr. Biol. 2006, 16:808-813.
-
(2006)
Curr. Biol.
, vol.16
, pp. 808-813
-
-
Kambris, Z.1
Brun, S.2
Jang, I.H.3
Nam, H.J.4
Romeo, Y.5
Takahashi, K.6
Lee, W.J.7
Ueda, R.8
Lemaitre, B.9
-
55
-
-
15944420868
-
Bacterial recognition and signaling by the Drosophila IMD pathway
-
Kaneko T., Silverman N. Bacterial recognition and signaling by the Drosophila IMD pathway. Cell Microbiol. 2005, 7:461-469.
-
(2005)
Cell Microbiol.
, vol.7
, pp. 461-469
-
-
Kaneko, T.1
Silverman, N.2
-
56
-
-
33745225236
-
PGRP-LC and PGRP-LE have essential yet distinct functions in the drosophila immune response to monomeric DAP-type peptidoglycan
-
Kaneko T., Yano T., Aggarwal K., Lim J.H., Ueda K., Oshima Y., Peach C., Erturk-Hasdemir D., Goldman W.E., Oh B.H., Kurata S., Silverman N. PGRP-LC and PGRP-LE have essential yet distinct functions in the drosophila immune response to monomeric DAP-type peptidoglycan. Nat. Immunol. 2006, 7:715-723.
-
(2006)
Nat. Immunol.
, vol.7
, pp. 715-723
-
-
Kaneko, T.1
Yano, T.2
Aggarwal, K.3
Lim, J.H.4
Ueda, K.5
Oshima, Y.6
Peach, C.7
Erturk-Hasdemir, D.8
Goldman, W.E.9
Oh, B.H.10
Kurata, S.11
Silverman, N.12
-
57
-
-
76049127722
-
Dynamics of the Dorsal morphogen gradient
-
Kanodia J.S., Rikhy R., Kim Y., Lund V.K., DeLotto R., Lippincott-Schwartz J., Shvartsman S.Y. Dynamics of the Dorsal morphogen gradient. Proc. Natl. Acad. Sci. USA 2009, 106:21707-21712.
-
(2009)
Proc. Natl. Acad. Sci. USA
, vol.106
, pp. 21707-21712
-
-
Kanodia, J.S.1
Rikhy, R.2
Kim, Y.3
Lund, V.K.4
DeLotto, R.5
Lippincott-Schwartz, J.6
Shvartsman, S.Y.7
-
58
-
-
0033996762
-
The IκB kinase (IKK) and NF-κB: key elements of proinflammatory signaling
-
Karin M., Delhase M. The IκB kinase (IKK) and NF-κB: key elements of proinflammatory signaling. Semin. Immunol. 2000, 12:85-98.
-
(2000)
Semin. Immunol.
, vol.12
, pp. 85-98
-
-
Karin, M.1
Delhase, M.2
-
59
-
-
79956300649
-
Toll-like receptors and their crosstalk with other innate receptors in infection and immunity
-
Kawai T., Akira S. Toll-like receptors and their crosstalk with other innate receptors in infection and immunity. Immunity 2011, 34:637-650.
-
(2011)
Immunity
, vol.34
, pp. 637-650
-
-
Kawai, T.1
Akira, S.2
-
60
-
-
51349158231
-
Signaling adaptors used by Toll-like receptors: an update
-
Kenny E.F., O'Neill L.A. Signaling adaptors used by Toll-like receptors: an update. Cytokine 2008, 43:342-349.
-
(2008)
Cytokine
, vol.43
, pp. 342-349
-
-
Kenny, E.F.1
O'Neill, L.A.2
-
61
-
-
20444438434
-
Overview of innate immunity in Drosophila
-
Kim T., Kim Y.J. Overview of innate immunity in Drosophila. J. Biochem. Mol. Biol. 2005, 38:121-127.
-
(2005)
J. Biochem. Mol. Biol.
, vol.38
, pp. 121-127
-
-
Kim, T.1
Kim, Y.J.2
-
62
-
-
77953449985
-
A large-scale RNAi screen identifies Deaf1 as a regulator of innate immune responses in Drosophila
-
Kuttenkeuler D., Pelte N., Ragab A., Gesellchen V., Schneider L., Blass C., Axelsson E., Huber W., Boutros M. A large-scale RNAi screen identifies Deaf1 as a regulator of innate immune responses in Drosophila. J. Innate Immun. 2010, 2:181-194.
-
(2010)
J. Innate Immun.
, vol.2
, pp. 181-194
-
-
Kuttenkeuler, D.1
Pelte, N.2
Ragab, A.3
Gesellchen, V.4
Schneider, L.5
Blass, C.6
Axelsson, E.7
Huber, W.8
Boutros, M.9
-
63
-
-
34047268684
-
The host defense of Drosophila melanogaster
-
Lemaitre B., Hoffmann J. The host defense of Drosophila melanogaster. Annu. Rev. Immunol. 2007, 25:697-743.
-
(2007)
Annu. Rev. Immunol.
, vol.25
, pp. 697-743
-
-
Lemaitre, B.1
Hoffmann, J.2
-
64
-
-
0028865526
-
A recessive mutation, immune deficiency (imd), defines two distinct control pathways in the Drosophila host defense
-
Lemaitre B., Kromer-Metzger E., Michaut L., Nicolas E., Meister M., Georgel P., Reichhart J.M., Hoffmann J.A. A recessive mutation, immune deficiency (imd), defines two distinct control pathways in the Drosophila host defense. Proc. Natl. Acad. Sci. USA 1995, 92:9465-9469.
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 9465-9469
-
-
Lemaitre, B.1
Kromer-Metzger, E.2
Michaut, L.3
Nicolas, E.4
Meister, M.5
Georgel, P.6
Reichhart, J.M.7
Hoffmann, J.A.8
-
65
-
-
0028877993
-
Functional analysis and regulation of nuclear import of dorsal during the immune response in Drosophila
-
Lemaitre B., Meister M., Govind S., Georgel P., Steward R., Reichhart J.M., Hoffmann J.A. Functional analysis and regulation of nuclear import of dorsal during the immune response in Drosophila. EMBO J. 1995, 14:536-545.
-
(1995)
EMBO J.
, vol.14
, pp. 536-545
-
-
Lemaitre, B.1
Meister, M.2
Govind, S.3
Georgel, P.4
Steward, R.5
Reichhart, J.M.6
Hoffmann, J.A.7
-
66
-
-
0031446642
-
Drosophila host defense: differential induction of antimicrobial peptide genes after infection by various classes of microorganisms
-
Lemaitre B., Reichhart J.M., Hoffmann J.A. Drosophila host defense: differential induction of antimicrobial peptide genes after infection by various classes of microorganisms. Proc. Natl. Acad. Sci. USA 1997, 94:14614-14619.
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 14614-14619
-
-
Lemaitre, B.1
Reichhart, J.M.2
Hoffmann, J.A.3
-
67
-
-
0038664357
-
The Drosophila immune system detects bacteria through specific peptidoglycan recognition
-
Leulier F., Parquet C., Pili-Floury S., Ryu J.H., Caroff M., Lee W.J., Mengin-Lecreulx D., Lemaitre B. The Drosophila immune system detects bacteria through specific peptidoglycan recognition. Nat. Immunol. 2003, 4:478-484.
-
(2003)
Nat. Immunol.
, vol.4
, pp. 478-484
-
-
Leulier, F.1
Parquet, C.2
Pili-Floury, S.3
Ryu, J.H.4
Caroff, M.5
Lee, W.J.6
Mengin-Lecreulx, D.7
Lemaitre, B.8
-
68
-
-
0028884812
-
Metchnikowin, a novel immune-inducible proline-rich peptide from Drosophila with antibacterial and antifungal properties
-
Levashina E.A., Ohresser S., Bulet P., Reichhart J.M., Hetru C., Hoffmann J.A. Metchnikowin, a novel immune-inducible proline-rich peptide from Drosophila with antibacterial and antifungal properties. Eur. J. Biochem. 1995, 233:694-700.
-
(1995)
Eur. J. Biochem.
, vol.233
, pp. 694-700
-
-
Levashina, E.A.1
Ohresser, S.2
Bulet, P.3
Reichhart, J.M.4
Hetru, C.5
Hoffmann, J.A.6
-
69
-
-
0033578917
-
Constitutive activation of toll-mediated antifungal defense in serpin-deficient Drosophila
-
Levashina E.A., Langley E., Green C., Gubb D., Ashburner M., Hoffmann J.A., Reichhart J.M. Constitutive activation of toll-mediated antifungal defense in serpin-deficient Drosophila. Science 1999, 285:1917-1919.
-
(1999)
Science
, vol.285
, pp. 1917-1919
-
-
Levashina, E.A.1
Langley, E.2
Green, C.3
Gubb, D.4
Ashburner, M.5
Hoffmann, J.A.6
Reichhart, J.M.7
-
70
-
-
0036023960
-
Critical evaluation of the role of the Toll-like receptor 18-wheeler in the host defense of Drosophila
-
Ligoxygakis P., Bulet P., Reichhart J.M. Critical evaluation of the role of the Toll-like receptor 18-wheeler in the host defense of Drosophila. EMBO Rep. 2002, 3:666-673.
-
(2002)
EMBO Rep.
, vol.3
, pp. 666-673
-
-
Ligoxygakis, P.1
Bulet, P.2
Reichhart, J.M.3
-
71
-
-
0037025213
-
Activation of Drosophila Toll during fungal infection by a blood serine protease
-
Ligoxygakis P., Pelte N., Hoffmann J.A., Reichhart J.M. Activation of Drosophila Toll during fungal infection by a blood serine protease. Science 2002, 297:114-116.
-
(2002)
Science
, vol.297
, pp. 114-116
-
-
Ligoxygakis, P.1
Pelte, N.2
Hoffmann, J.A.3
Reichhart, J.M.4
-
72
-
-
77953714711
-
Helical assembly in the MyD88-IRAK4-IRAK2 complex in TLR/IL-1R signaling
-
Lin S.C., Lo Y.C., Wu H. Helical assembly in the MyD88-IRAK4-IRAK2 complex in TLR/IL-1R signaling. Nature 2010, 465:885-890.
-
(2010)
Nature
, vol.465
, pp. 885-890
-
-
Lin, S.C.1
Lo, Y.C.2
Wu, H.3
-
73
-
-
0035187882
-
The antibacterial arm of the drosophila innate immune response requires an IkappaB kinase
-
Lu Y., Wu L.P., Anderson K.V. The antibacterial arm of the drosophila innate immune response requires an IkappaB kinase. Genes Dev. 2001, 15:104-110.
-
(2001)
Genes Dev.
, vol.15
, pp. 104-110
-
-
Lu, Y.1
Wu, L.P.2
Anderson, K.V.3
-
74
-
-
78149245452
-
Endocytosis is required for Toll signaling and shaping of the Dorsal/NF-kappaB morphogen gradient during Drosophila embryogenesis
-
Lund V.K., DeLotto Y., DeLotto R. Endocytosis is required for Toll signaling and shaping of the Dorsal/NF-kappaB morphogen gradient during Drosophila embryogenesis. Proc. Natl. Acad. Sci. USA 2010, 107:18028-18033.
-
(2010)
Proc. Natl. Acad. Sci. USA
, vol.107
, pp. 18028-18033
-
-
Lund, V.K.1
DeLotto, Y.2
DeLotto, R.3
-
75
-
-
0034777255
-
Tehao functions in the Toll pathway in Drosophila melanogaster: possible roles in development and innate immunity
-
Luo C., Shen B., Manley J.L., Zheng L. Tehao functions in the Toll pathway in Drosophila melanogaster: possible roles in development and innate immunity. Insect Mol. Biol. 2001, 10:457-464.
-
(2001)
Insect Mol. Biol.
, vol.10
, pp. 457-464
-
-
Luo, C.1
Shen, B.2
Manley, J.L.3
Zheng, L.4
-
76
-
-
0033564614
-
A mosaic analysis in Drosophila fat body cells of the control of antimicrobial peptide genes by the Rel proteins Dorsal and DIF
-
Manfruelli P., Reichhart J.M., Steward R., Hoffmann J.A., Lemaitre B. A mosaic analysis in Drosophila fat body cells of the control of antimicrobial peptide genes by the Rel proteins Dorsal and DIF. EMBO J. 1999, 18:3380-3391.
-
(1999)
EMBO J.
, vol.18
, pp. 3380-3391
-
-
Manfruelli, P.1
Reichhart, J.M.2
Steward, R.3
Hoffmann, J.A.4
Lemaitre, B.5
-
77
-
-
84859985764
-
Phosphoinositide binding by the Toll adaptor dMyD88 controls antibacterial responses in Drosophila
-
Marek L.R., Kagan J.C. Phosphoinositide binding by the Toll adaptor dMyD88 controls antibacterial responses in Drosophila. Immunity 2012, 36:612-622.
-
(2012)
Immunity
, vol.36
, pp. 612-622
-
-
Marek, L.R.1
Kagan, J.C.2
-
78
-
-
24744466064
-
Sterile wounding is a minimal and sufficient trigger for a cellular immune response in Drosophila melanogaster
-
Markus R., Kurucz E., Rus F., Ando I. Sterile wounding is a minimal and sufficient trigger for a cellular immune response in Drosophila melanogaster. Immunol. Lett. 2005, 101:108-111.
-
(2005)
Immunol. Lett.
, vol.101
, pp. 108-111
-
-
Markus, R.1
Kurucz, E.2
Rus, F.3
Ando, I.4
-
79
-
-
76649110197
-
Drosophila Rel proteins are central regulators of a robust, multi-organ immune network
-
Matova N., Anderson K.V. Drosophila Rel proteins are central regulators of a robust, multi-organ immune network. J. Cell Sci. 2010, 123:627-633.
-
(2010)
J. Cell Sci.
, vol.123
, pp. 627-633
-
-
Matova, N.1
Anderson, K.V.2
-
80
-
-
77951740257
-
The Drosophila PRR GNBP3 assembles effector complexes involved in antifungal defenses independently of its Toll-pathway activation function
-
Matskevich A.A., Quintin J., Ferrandon D. The Drosophila PRR GNBP3 assembles effector complexes involved in antifungal defenses independently of its Toll-pathway activation function. Eur. J. Immunol. 2010, 40:1244-1254.
-
(2010)
Eur. J. Immunol.
, vol.40
, pp. 1244-1254
-
-
Matskevich, A.A.1
Quintin, J.2
Ferrandon, D.3
-
81
-
-
84862189464
-
Ubiquitylation of the initiator caspase DREDD is required for innate immune signaling
-
Meinander A., Runchel C., Tenev T., Chen L., Kim C.H., Ribeiro P.S., Broemer M., Leulier F., Zvelebil M., Silverman N., Meier P. Ubiquitylation of the initiator caspase DREDD is required for innate immune signaling. EMBO J. 2012, 31:2770-2783.
-
(2012)
EMBO J.
, vol.31
, pp. 2770-2783
-
-
Meinander, A.1
Runchel, C.2
Tenev, T.3
Chen, L.4
Kim, C.H.5
Ribeiro, P.S.6
Broemer, M.7
Leulier, F.8
Zvelebil, M.9
Silverman, N.10
Meier, P.11
-
82
-
-
0033118490
-
Toll receptor-mediated Drosophila immune response requires Dif, an NF-kappaB factor
-
Meng X., Khanuja B.S., Ip Y.T. Toll receptor-mediated Drosophila immune response requires Dif, an NF-kappaB factor. Genes Dev. 1999, 13:792-797.
-
(1999)
Genes Dev.
, vol.13
, pp. 792-797
-
-
Meng, X.1
Khanuja, B.S.2
Ip, Y.T.3
-
83
-
-
0035856990
-
Drosophila Toll is activated by Gram-positive bacteria through a circulating peptidoglycan recognition protein
-
Michel T., Reichhart J.M., Hoffmann J.A., Royet J. Drosophila Toll is activated by Gram-positive bacteria through a circulating peptidoglycan recognition protein. Nature 2001, 414:756-759.
-
(2001)
Nature
, vol.414
, pp. 756-759
-
-
Michel, T.1
Reichhart, J.M.2
Hoffmann, J.A.3
Royet, J.4
-
84
-
-
0035367786
-
A novel human gene (SARM) at chromosome 17q11 encodes a protein with a SAM motif and structural similarity to Armadillo/beta-catenin that is conserved in mouse, Drosophila, and Caenorhabditis elegans
-
Mink M., Fogelgren B., Olszewski K., Maroy P., Csiszar K. A novel human gene (SARM) at chromosome 17q11 encodes a protein with a SAM motif and structural similarity to Armadillo/beta-catenin that is conserved in mouse, Drosophila, and Caenorhabditis elegans. Genomics 2001, 74:234-244.
-
(2001)
Genomics
, vol.74
, pp. 234-244
-
-
Mink, M.1
Fogelgren, B.2
Olszewski, K.3
Maroy, P.4
Csiszar, K.5
-
85
-
-
57749089751
-
Assembly of oligomeric death domain complexes during Toll receptor signaling
-
Moncrieffe M.C., Grossmann J.G., Gay N.J. Assembly of oligomeric death domain complexes during Toll receptor signaling. J. Biol. Chem. 2008, 283:33447-33454.
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 33447-33454
-
-
Moncrieffe, M.C.1
Grossmann, J.G.2
Gay, N.J.3
-
86
-
-
69949161905
-
An oligomeric signaling platform formed by the Toll-like receptor signal transducers MyD88 and IRAK-4
-
Motshwene P.G., Moncrieffe M.C., Grossmann J.G., Kao C., Ayaluru M., Sandercock A.M., Robinson C.V., Latz E., Gay N.J. An oligomeric signaling platform formed by the Toll-like receptor signal transducers MyD88 and IRAK-4. J. Biol. Chem. 2009, 284:25404-25411.
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 25404-25411
-
-
Motshwene, P.G.1
Moncrieffe, M.C.2
Grossmann, J.G.3
Kao, C.4
Ayaluru, M.5
Sandercock, A.M.6
Robinson, C.V.7
Latz, E.8
Gay, N.J.9
-
87
-
-
0025606964
-
Proclotting enzyme from horseshoe crab hemocytes. cDNA cloning, disulfide locations, and subcellular localization
-
Muta T., Hashimoto R., Miyata T., Nishimura H., Toh Y., Iwanaga S. Proclotting enzyme from horseshoe crab hemocytes. cDNA cloning, disulfide locations, and subcellular localization. J. Biol. Chem. 1990, 265:22426-22433.
-
(1990)
J. Biol. Chem.
, vol.265
, pp. 22426-22433
-
-
Muta, T.1
Hashimoto, R.2
Miyata, T.3
Nishimura, H.4
Toh, Y.5
Iwanaga, S.6
-
88
-
-
84859991798
-
Virus recognition by Toll-7 activates antiviral autophagy in Drosophila
-
Nakamoto M., Moy R.H., Xu J., Bambina S., Yasunaga A., Shelly S.S., Gold B., Cherry S. Virus recognition by Toll-7 activates antiviral autophagy in Drosophila. Immunity 2012, 36:658-667.
-
(2012)
Immunity
, vol.36
, pp. 658-667
-
-
Nakamoto, M.1
Moy, R.H.2
Xu, J.3
Bambina, S.4
Yasunaga, A.5
Shelly, S.S.6
Gold, B.7
Cherry, S.8
-
89
-
-
79952239984
-
Lack of an antibacterial response defect in Drosophila Toll-9 mutant
-
Narbonne-Reveau K., Charroux B., Royet J. Lack of an antibacterial response defect in Drosophila Toll-9 mutant. PLoS One 2011, 6:e17470.
-
(2011)
PLoS One
, vol.6
-
-
Narbonne-Reveau, K.1
Charroux, B.2
Royet, J.3
-
90
-
-
0023659112
-
Determination of anteroposterior polarity in Drosophila
-
Nüsslein-Volhard C., Frohnhofer H.G., Lehmann R. Determination of anteroposterior polarity in Drosophila. Science 1987, 238:1675-1681.
-
(1987)
Science
, vol.238
, pp. 1675-1681
-
-
Nüsslein-Volhard, C.1
Frohnhofer, H.G.2
Lehmann, R.3
-
91
-
-
0036166242
-
The Drosophila Toll-9 activates a constitutive antimicrobial defense
-
Ooi J.Y., Yagi Y., Hu X., Ip Y.T. The Drosophila Toll-9 activates a constitutive antimicrobial defense. EMBO Rep. 2002, 3:82-87.
-
(2002)
EMBO Rep.
, vol.3
, pp. 82-87
-
-
Ooi, J.Y.1
Yagi, Y.2
Hu, X.3
Ip, Y.T.4
-
92
-
-
84864332905
-
DSarm/Sarm1 is required for activation of an injury-induced axon death pathway
-
Osterloh J.M., Yang J., Rooney T.M., Fox A.N., Adalbert R., Powell E.H., Sheehan A.E., Avery M.A., Hackett R., Logan M.A., MacDonald J.M., Ziegenfuss J.S., Milde S., Hou Y.J., Nathan C., Ding A., Brown R.H., Conforti L., Coleman M., Tessier-Lavigne M., Zuchner S., Freeman M.R. DSarm/Sarm1 is required for activation of an injury-induced axon death pathway. Science 2012, 337:481-484.
-
(2012)
Science
, vol.337
, pp. 481-484
-
-
Osterloh, J.M.1
Yang, J.2
Rooney, T.M.3
Fox, A.N.4
Adalbert, R.5
Powell, E.H.6
Sheehan, A.E.7
Avery, M.A.8
Hackett, R.9
Logan, M.A.10
MacDonald, J.M.11
Ziegenfuss, J.S.12
Milde, S.13
Hou, Y.J.14
Nathan, C.15
Ding, A.16
Brown, R.H.17
Conforti, L.18
Coleman, M.19
Tessier-Lavigne, M.20
Zuchner, S.21
Freeman, M.R.22
more..
-
93
-
-
20344389060
-
Toll-like receptors: linking innate and adaptive immunity
-
Pasare C., Medzhitov R. Toll-like receptors: linking innate and adaptive immunity. Adv. Exp. Med. Biol. 2005, 560:11-18.
-
(2005)
Adv. Exp. Med. Biol.
, vol.560
, pp. 11-18
-
-
Pasare, C.1
Medzhitov, R.2
-
94
-
-
77953315434
-
SARM inhibits both TRIF- and MyD88-mediated AP-1 activation
-
Peng J., Yuan Q., Lin B., Panneerselvam P., Wang X., Luan X.L., Lim S.K., Leung B.P., Ho B., Ding J.L. SARM inhibits both TRIF- and MyD88-mediated AP-1 activation. Eur. J. Immunol. 2010, 40:1738-1747.
-
(2010)
Eur. J. Immunol.
, vol.40
, pp. 1738-1747
-
-
Peng, J.1
Yuan, Q.2
Lin, B.3
Panneerselvam, P.4
Wang, X.5
Luan, X.L.6
Lim, S.K.7
Leung, B.P.8
Ho, B.9
Ding, J.L.10
-
95
-
-
29244478349
-
Crystal structure of a clip-domain serine protease and functional roles of the clip domains
-
Piao S., Song Y.L., Kim J.H., Park S.Y., Park J.W., Lee B.L., Oh B.H., Ha N.C. Crystal structure of a clip-domain serine protease and functional roles of the clip domains. EMBO J. 2005, 24:4404-4414.
-
(2005)
EMBO J.
, vol.24
, pp. 4404-4414
-
-
Piao, S.1
Song, Y.L.2
Kim, J.H.3
Park, S.Y.4
Park, J.W.5
Lee, B.L.6
Oh, B.H.7
Ha, N.C.8
-
96
-
-
0032509295
-
Defective LPS signaling in C3H/HeJ and C57BL/10ScCr mice: mutations in Tlr4 gene
-
Poltorak A., He X., Smirnova I., Liu M.Y., Huffel C.V., Du X., Birdwell D., Alejos E., Silva M., Galanos C., Freudenberg M., Ricciardi-Castagnoli P., Layton B., Beutler B. Defective LPS signaling in C3H/HeJ and C57BL/10ScCr mice: mutations in Tlr4 gene. Science 1998, 282:2085-2088.
-
(1998)
Science
, vol.282
, pp. 2085-2088
-
-
Poltorak, A.1
He, X.2
Smirnova, I.3
Liu, M.Y.4
Huffel, C.V.5
Du, X.6
Birdwell, D.7
Alejos, E.8
Silva, M.9
Galanos, C.10
Freudenberg, M.11
Ricciardi-Castagnoli, P.12
Layton, B.13
Beutler, B.14
-
97
-
-
0031748547
-
A role for the Drosophila Toll/Cactus pathway in larval hematopoiesis
-
Qiu P., Pan P.C., Govind S. A role for the Drosophila Toll/Cactus pathway in larval hematopoiesis. Development 1998, 125:1909-1920.
-
(1998)
Development
, vol.125
, pp. 1909-1920
-
-
Qiu, P.1
Pan, P.C.2
Govind, S.3
-
98
-
-
0034303573
-
Role of Drosophila IKK gamma in a Toll-independent antibacterial immune response
-
Rutschmann S., Jung A.C., Zhou R., Silverman N., Hoffmann J.A., Ferrandon D. Role of Drosophila IKK gamma in a Toll-independent antibacterial immune response. Nat. Immunol. 2000, 1:342-347.
-
(2000)
Nat. Immunol.
, vol.1
, pp. 342-347
-
-
Rutschmann, S.1
Jung, A.C.2
Zhou, R.3
Silverman, N.4
Hoffmann, J.A.5
Ferrandon, D.6
-
99
-
-
0028182623
-
A processed form of the Spatzle protein defines dorsal-ventral polarity in the Drosophila embryo
-
Schneider D.S., Jin Y., Morisato D., Anderson K.V. A processed form of the Spatzle protein defines dorsal-ventral polarity in the Drosophila embryo. Development 1994, 120:1243-1250.
-
(1994)
Development
, vol.120
, pp. 1243-1250
-
-
Schneider, D.S.1
Jin, Y.2
Morisato, D.3
Anderson, K.V.4
-
100
-
-
0037383779
-
Induction of neuron-specific glycosylation by Tollo/Toll-8, a Drosophila Toll-like receptor expressed in non-neural cells
-
Seppo A., Matani P., Sharrow M., Tiemeyer M. Induction of neuron-specific glycosylation by Tollo/Toll-8, a Drosophila Toll-like receptor expressed in non-neural cells. Development 2003, 130:1439-1448.
-
(2003)
Development
, vol.130
, pp. 1439-1448
-
-
Seppo, A.1
Matani, P.2
Sharrow, M.3
Tiemeyer, M.4
-
101
-
-
64049114864
-
Autophagy is an essential component of Drosophila immunity against vesicular stomatitis virus
-
Shelly S., Lukinova N., Bambina S., Berman A., Cherry S. Autophagy is an essential component of Drosophila immunity against vesicular stomatitis virus. Immunity 2009, 30:588-598.
-
(2009)
Immunity
, vol.30
, pp. 588-598
-
-
Shelly, S.1
Lukinova, N.2
Bambina, S.3
Berman, A.4
Cherry, S.5
-
102
-
-
0034287444
-
A Drosophila IkappaB kinase complex required for Relish cleavage and antibacterial immunity
-
Silverman N., Zhou R., Stoven S., Pandey N., Hultmark D., Maniatis T. A Drosophila IkappaB kinase complex required for Relish cleavage and antibacterial immunity. Genes Dev. 2000, 14:2461-2471.
-
(2000)
Genes Dev.
, vol.14
, pp. 2461-2471
-
-
Silverman, N.1
Zhou, R.2
Stoven, S.3
Pandey, N.4
Hultmark, D.5
Maniatis, T.6
-
103
-
-
1542571463
-
Immune activation of NF-kappaB and JNK requires Drosophila TAK1
-
Silverman N., Zhou R., Erlich R.L., Hunter M., Bernstein E., Schneider D., Maniatis T. Immune activation of NF-kappaB and JNK requires Drosophila TAK1. J. Biol. Chem. 2003, 278:48928-48934.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 48928-48934
-
-
Silverman, N.1
Zhou, R.2
Erlich, R.L.3
Hunter, M.4
Bernstein, E.5
Schneider, D.6
Maniatis, T.7
-
104
-
-
0037184519
-
Whole-genome analysis of dorsal-ventral patterning in the Drosophila embryo
-
Stathopoulos A., Van Drenth M., Erives A., Markstein M., Levine M. Whole-genome analysis of dorsal-ventral patterning in the Drosophila embryo. Cell 2002, 111:687-701.
-
(2002)
Cell
, vol.111
, pp. 687-701
-
-
Stathopoulos, A.1
Van Drenth, M.2
Erives, A.3
Markstein, M.4
Levine, M.5
-
105
-
-
0026202063
-
Establishment of dorsal-ventral and terminal pattern in the Drosophila embryo
-
Stein D.S., Stevens L.M. Establishment of dorsal-ventral and terminal pattern in the Drosophila embryo. Curr. Opin. Genet. Dev. 1991, 1:247-254.
-
(1991)
Curr. Opin. Genet. Dev.
, vol.1
, pp. 247-254
-
-
Stein, D.S.1
Stevens, L.M.2
-
106
-
-
0019386682
-
Sequence and specificity of two antibacterial proteins involved in insect immunity
-
Steiner H., Hultmark D., Engstrom A., Bennich H., Boman H.G. Sequence and specificity of two antibacterial proteins involved in insect immunity. Nature 1981, 292:246-248.
-
(1981)
Nature
, vol.292
, pp. 246-248
-
-
Steiner, H.1
Hultmark, D.2
Engstrom, A.3
Bennich, H.4
Boman, H.G.5
-
107
-
-
0023619362
-
Dorsal, an embryonic polarity gene in Drosophila, is homologous to the vertebrate proto-oncogene, c-rel
-
Steward R. Dorsal, an embryonic polarity gene in Drosophila, is homologous to the vertebrate proto-oncogene, c-rel. Science 1987, 238:692-694.
-
(1987)
Science
, vol.238
, pp. 692-694
-
-
Steward, R.1
-
108
-
-
0038284956
-
Caspase-mediated processing of the Drosophila NF-kappaB factor Relish
-
Stoven S., Silverman N., Junell A., Hedengren-Olcott M., Erturk D., Engstrom Y., Maniatis T., Hultmark D. Caspase-mediated processing of the Drosophila NF-kappaB factor Relish. Proc. Natl. Acad. Sci. USA 2003, 100:5991-5996.
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 5991-5996
-
-
Stoven, S.1
Silverman, N.2
Junell, A.3
Hedengren-Olcott, M.4
Erturk, D.5
Engstrom, Y.6
Maniatis, T.7
Hultmark, D.8
-
109
-
-
0036791016
-
A heterotrimeric death domain complex in Toll signaling
-
Sun H., Bristow B.N., Qu G., Wasserman S.A. A heterotrimeric death domain complex in Toll signaling. Proc. Natl. Acad. Sci. USA 2002, 99:12871-12876.
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 12871-12876
-
-
Sun, H.1
Bristow, B.N.2
Qu, G.3
Wasserman, S.A.4
-
110
-
-
0842307067
-
Regulated assembly of the Toll signaling complex drives Drosophila dorsoventral patterning
-
Sun H., Towb P., Chiem D.N., Foster B.A., Wasserman S.A. Regulated assembly of the Toll signaling complex drives Drosophila dorsoventral patterning. EMBO J. 2004, 23:100-110.
-
(2004)
EMBO J.
, vol.23
, pp. 100-110
-
-
Sun, H.1
Towb, P.2
Chiem, D.N.3
Foster, B.A.4
Wasserman, S.A.5
-
111
-
-
34250221179
-
Toll and IMD pathways synergistically activate an innate immune response in Drosophila melanogaster
-
Tanji T., Hu X., Weber A.N., Ip Y.T. Toll and IMD pathways synergistically activate an innate immune response in Drosophila melanogaster. Mol. Cell. Biol. 2007, 27:4578-4588.
-
(2007)
Mol. Cell. Biol.
, vol.27
, pp. 4578-4588
-
-
Tanji, T.1
Hu, X.2
Weber, A.N.3
Ip, Y.T.4
-
112
-
-
77957078396
-
Heterodimers of NF-kappaB transcription factors DIF and Relish regulate antimicrobial peptide genes in Drosophila
-
Tanji T., Yun E.Y., Ip Y.T. Heterodimers of NF-kappaB transcription factors DIF and Relish regulate antimicrobial peptide genes in Drosophila. Proc. Natl. Acad. Sci. USA 2010, 107:14715-14720.
-
(2010)
Proc. Natl. Acad. Sci. USA
, vol.107
, pp. 14715-14720
-
-
Tanji, T.1
Yun, E.Y.2
Ip, Y.T.3
-
113
-
-
0027275490
-
A novel domain within the 55kd TNF receptor signals cell death
-
Tartaglia L.A., Ayres T.M., Wong G.H., Goeddel D.V. A novel domain within the 55kd TNF receptor signals cell death. Cell 1993, 74:845-853.
-
(1993)
Cell
, vol.74
, pp. 845-853
-
-
Tartaglia, L.A.1
Ayres, T.M.2
Wong, G.H.3
Goeddel, D.V.4
-
114
-
-
0034641738
-
Toll-related receptors and the control of antimicrobial peptide expression in Drosophila
-
Tauszig S., Jouanguy E., Hoffmann J.A., Imler J.L. Toll-related receptors and the control of antimicrobial peptide expression in Drosophila. Proc. Natl. Acad. Sci. USA 2000, 97:10520-10525.
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 10520-10525
-
-
Tauszig, S.1
Jouanguy, E.2
Hoffmann, J.A.3
Imler, J.L.4
-
115
-
-
0036141954
-
Drosophila MyD88 is required for the response to fungal and Gram-positive bacterial infections
-
Tauszig-Delamasure S., Bilak H., Capovilla M., Hoffmann J.A., Imler J.L. Drosophila MyD88 is required for the response to fungal and Gram-positive bacterial infections. Nat. Immunol. 2002, 3:91-97.
-
(2002)
Nat. Immunol.
, vol.3
, pp. 91-97
-
-
Tauszig-Delamasure, S.1
Bilak, H.2
Capovilla, M.3
Hoffmann, J.A.4
Imler, J.L.5
-
116
-
-
0031901916
-
Recruitment of Tube and Pelle to signaling sites at the surface of the Drosophila embryo
-
Towb P., Galindo R.L., Wasserman S.A. Recruitment of Tube and Pelle to signaling sites at the surface of the Drosophila embryo. Development 1998, 125:2443-2450.
-
(1998)
Development
, vol.125
, pp. 2443-2450
-
-
Towb, P.1
Galindo, R.L.2
Wasserman, S.A.3
-
117
-
-
77952370155
-
Tube Is an IRAK-4 homolog in a Toll pathway adapted for development and immunity
-
Towb P., Sun H., Wasserman S.A. Tube Is an IRAK-4 homolog in a Toll pathway adapted for development and immunity. J. Innate Immun. 2009, 1:309-321.
-
(2009)
J. Innate Immun.
, vol.1
, pp. 309-321
-
-
Towb, P.1
Sun, H.2
Wasserman, S.A.3
-
118
-
-
0037133259
-
Constitutive expression of a single antimicrobial peptide can restore wild-type resistance to infection in immunodeficient Drosophila mutants
-
Tzou P., Reichhart J.M., Lemaitre B. Constitutive expression of a single antimicrobial peptide can restore wild-type resistance to infection in immunodeficient Drosophila mutants. Proc. Natl. Acad. Sci. USA 2002, 99:2152-2157.
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 2152-2157
-
-
Tzou, P.1
Reichhart, J.M.2
Lemaitre, B.3
-
119
-
-
77953423842
-
Genome-wide RNA interference in Drosophila cells identifies G protein-coupled receptor kinase 2 as a conserved regulator of NF-kappaB signaling
-
Valanne S., Myllymaki H., Kallio J., Schmid M.R., Kleino A., Murumagi A., Airaksinen L., Kotipelto T., Kaustio M., Ulvila J., Esfahani S.S., Engstrom Y., Silvennoinen O., Hultmark D., Parikka M., Ramet M. Genome-wide RNA interference in Drosophila cells identifies G protein-coupled receptor kinase 2 as a conserved regulator of NF-kappaB signaling. J. Immunol. 2010, 184:6188-6198.
-
(2010)
J. Immunol.
, vol.184
, pp. 6188-6198
-
-
Valanne, S.1
Myllymaki, H.2
Kallio, J.3
Schmid, M.R.4
Kleino, A.5
Murumagi, A.6
Airaksinen, L.7
Kotipelto, T.8
Kaustio, M.9
Ulvila, J.10
Esfahani, S.S.11
Engstrom, Y.12
Silvennoinen, O.13
Hultmark, D.14
Parikka, M.15
Ramet, M.16
-
120
-
-
79251557500
-
The Drosophila Toll signaling pathway
-
Valanne S., Wang J.H., Ramet M. The Drosophila Toll signaling pathway. J. Immunol. 2011, 186:649-656.
-
(2011)
J. Immunol.
, vol.186
, pp. 649-656
-
-
Valanne, S.1
Wang, J.H.2
Ramet, M.3
-
121
-
-
53649108019
-
Molecular architecture of the fruit fly's airway epithelial immune system
-
Wagner C., Isermann K., Fehrenbach H., Roeder T. Molecular architecture of the fruit fly's airway epithelial immune system. BMC Genomics 2008, 9:446.
-
(2008)
BMC Genomics
, vol.9
, pp. 446
-
-
Wagner, C.1
Isermann, K.2
Fehrenbach, H.3
Roeder, T.4
-
123
-
-
0033860124
-
Toll signaling: the enigma variations
-
Wasserman S.A. Toll signaling: the enigma variations. Curr. Opin. Genet. Dev. 2000, 10:497-502.
-
(2000)
Curr. Opin. Genet. Dev.
, vol.10
, pp. 497-502
-
-
Wasserman, S.A.1
-
124
-
-
77953722967
-
Structural biology: immunity takes a heavy Toll
-
Wasserman S.A. Structural biology: immunity takes a heavy Toll. Nature 2010, 465:882-883.
-
(2010)
Nature
, vol.465
, pp. 882-883
-
-
Wasserman, S.A.1
-
125
-
-
34250314533
-
Role of the Spatzle Pro-domain in the generation of an active Toll receptor ligand
-
Weber A.N., Gangloff M., Moncrieffe M.C., Hyvert Y., Imler J.L., Gay N.J. Role of the Spatzle Pro-domain in the generation of an active Toll receptor ligand. J. Biol. Chem. 2007, 282:13522-13531.
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 13522-13531
-
-
Weber, A.N.1
Gangloff, M.2
Moncrieffe, M.C.3
Hyvert, Y.4
Imler, J.L.5
Gay, N.J.6
-
126
-
-
0030663332
-
The 18-wheeler mutation reveals complex antibacterial gene regulation in Drosophila host defense
-
Williams M.J., Rodriguez A., Kimbrell D.A., Eldon E.D. The 18-wheeler mutation reveals complex antibacterial gene regulation in Drosophila host defense. EMBO J. 1997, 16:6120-6130.
-
(1997)
EMBO J.
, vol.16
, pp. 6120-6130
-
-
Williams, M.J.1
Rodriguez, A.2
Kimbrell, D.A.3
Eldon, E.D.4
-
127
-
-
0033601077
-
Three-dimensional structure of a complex between the death domains of Pelle and Tube
-
Xiao T., Towb P., Wasserman S.A., Sprang S.R. Three-dimensional structure of a complex between the death domains of Pelle and Tube. Cell 1999, 99:545-555.
-
(1999)
Cell
, vol.99
, pp. 545-555
-
-
Xiao, T.1
Towb, P.2
Wasserman, S.A.3
Sprang, S.R.4
-
128
-
-
78650205357
-
Functional analysis of Toll-related genes in Drosophila
-
Yagi Y., Nishida Y., Ip Y.T. Functional analysis of Toll-related genes in Drosophila. Dev. Growth Differ. 2010, 52:771-783.
-
(2010)
Dev. Growth Differ.
, vol.52
, pp. 771-783
-
-
Yagi, Y.1
Nishida, Y.2
Ip, Y.T.3
-
129
-
-
77953642433
-
Amphioxus SARM involved in neural development may function as a suppressor of TLR signaling
-
Yuan S., Wu K., Yang M., Xu L., Huang L., Liu H., Tao X., Huang S., Xu A. Amphioxus SARM involved in neural development may function as a suppressor of TLR signaling. J. Immunol. 2010, 184:6874-6881.
-
(2010)
J. Immunol.
, vol.184
, pp. 6874-6881
-
-
Yuan, S.1
Wu, K.2
Yang, M.3
Xu, L.4
Huang, L.5
Liu, H.6
Tao, X.7
Huang, S.8
Xu, A.9
|