-
2
-
-
51349158231
-
Signalling adaptors used by Toll-like receptors: An update
-
Kenny, E. F., and L. A. O'Neill. 2008. Signalling adaptors used by Toll-like receptors: an update. Cytokine 43: 342-349.
-
(2008)
Cytokine
, vol.43
, pp. 342-349
-
-
Kenny, E.F.1
O'Neill, L.A.2
-
3
-
-
75449093273
-
TIR-containing adaptors in Toll-like receptor signalling
-
Jenkins, K.A., and A. Mansell. 2009. TIR-containing adaptors in Toll-like receptor signalling. Cytokine 29: 237-244.
-
(2009)
Cytokine
, vol.29
, pp. 237-244
-
-
Jenkins, K.A.1
Mansell, A.2
-
4
-
-
0032133278
-
MyD88 is an adaptor protein in the hToll/IL-1 receptor family signaling pathways
-
Medzhitov, R., P. Preston-Hurlburt, E. Kopp, A. Stadlen, C. Chen, S. Ghosh, and C. A. Janeway, Jr. 1998. MyD88 is an adaptor protein in the hToll/IL-1 receptor family signaling pathways. Mol. Cell 2: 253-258.
-
(1998)
Mol. Cell
, vol.2
, pp. 253-258
-
-
Medzhitov, R.1
Preston-Hurlburt, P.2
Kopp, E.3
Stadlen, A.4
Chen, C.5
Ghosh, S.6
Janeway Jr., C.A.7
-
5
-
-
0035817925
-
Mal (MyD88-adapter-like) is required for Toll-like receptor-4 signal transduction
-
Fitzgerald, K. A., E. M. Palsson-McDermott, A. G. Bowie, C. A. Jefferies, A. S. Mansell, G. Brady, E. Brint, A. Dunne, P. Gray, M. T. Harte, et al. 2001. Mal (MyD88-adapter-like) is required for Toll-like receptor-4 signal transduction. Nature 413: 78-83.
-
(2001)
Nature
, vol.413
, pp. 78-83
-
-
Fitzgerald, K.A.1
Palsson-McDermott, E.M.2
Bowie, A.G.3
Jefferies, C.A.4
Mansell, A.S.5
Brady, G.6
Brint, E.7
Dunne, A.8
Gray, P.9
Harte, M.T.10
-
6
-
-
34547788305
-
The Troll in Toll: Mal and Tram as bridges for TLR2 and TLR4 signaling
-
Sheedy, F. J., and L. A. O'Neill. 2007. The Troll in Toll: Mal and Tram as bridges for TLR2 and TLR4 signaling. J. Leukoc. Biol. 82: 196-203.
-
(2007)
J. Leukoc. Biol.
, vol.82
, pp. 196-203
-
-
Sheedy, F.J.1
O'Neill, L.A.2
-
7
-
-
0037153191
-
Essential role for TIRAP in activation of the signalling cascade shared by TLR2 and TLR4
-
DOI 10.1038/nature01182
-
Yamamoto, M., S. Sato, H. Hemmi, H. Sanjo, S. Uematsu, T. Kaisho, K. Hoshino, O. Takeuchi, M. Kobayashi, T. Fujita, et al. 2002. Essential role for TIRAP in activation of the signalling cascade shared by TLR2 and TLR4. Nature 420: 324-329. (Pubitemid 35398188)
-
(2002)
Nature
, vol.420
, Issue.6913
, pp. 324-329
-
-
Yamamoto, M.1
Sato, S.2
Hemmi, H.3
Sanjo, H.4
Uematsu, S.5
Kaisho, T.6
Hoshino, K.7
Takeuchi, O.8
Kobayashi, M.9
Fujita, T.10
Takeda, K.11
Akira, S.12
-
8
-
-
2442605662
-
Mechanisms of the TRIF-induced interferon-stimulated response element and NF-kappaB activation and apoptosis pathways
-
Han, K. J., X. Su, L. G. Xu, L. H. Bin, J. Zhang, and H. B. Shu. 2004. Mechanisms of the TRIF-induced interferon-stimulated response element and NF-kappaB activation and apoptosis pathways. J. Biol. Chem. 279: 15652-15661.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 15652-15661
-
-
Han, K.J.1
Su, X.2
Xu, L.G.3
Bin, L.H.4
Zhang, J.5
Shu, H.B.6
-
9
-
-
40949134086
-
TRAM couples endocytosis of Toll-like receptor 4 to the induction of interferon-beta
-
Kagan, J. C., T. Su, T. Horng, A. Chow, S. Akira, and R. Medzhitov. 2008. TRAM couples endocytosis of Toll-like receptor 4 to the induction of interferon-beta. Nat. Immunol. 9: 361-368.
-
(2008)
Nat. Immunol.
, vol.9
, pp. 361-368
-
-
Kagan, J.C.1
Su, T.2
Horng, T.3
Chow, A.4
Akira, S.5
Medzhitov, R.6
-
10
-
-
0035367786
-
A novel human gene (SARM) at chromosome 17q11 encodes a protein with a SAM motif and structural similarity to Armadillo/beta-catenin that is conserved in mouse, Drosophila, and Caenorhabditis elegans
-
DOI 10.1006/geno.2001.6548
-
Mink, M., B. Fogelgren, K. Olszewski, P. Maroy, and K. Csiszar. 2001. A novel human gene (SARM) at chromosome 17q11 encodes a protein with a SAM motif and structural similarity to Armadillo/beta-catenin that is conserved in mouse, Drosophila, and Caenorhabditis elegans. Genomics 74: 234-244. (Pubitemid 32550145)
-
(2001)
Genomics
, vol.74
, Issue.2
, pp. 234-244
-
-
Mink, M.1
Fogelgren, B.2
Olszewski, K.3
Maroy, P.4
Csiszar, K.5
-
11
-
-
2442664007
-
TLR-independent control of innate immunity in Caenorhabditis elegans by the TIR domain adaptor protein TIR-1, an ortholog of human SARM
-
Couillault, C., N. Pujol, J. Reboul, L. Sabatier, J. F. Guichou, Y. Kohara, and J. J. Ewbank. 2004. TLR-independent control of innate immunity in Caenorhabditis elegans by the TIR domain adaptor protein TIR-1, an ortholog of human SARM. Nat. Immunol. 5: 488-494.
-
(2004)
Nat. Immunol.
, vol.5
, pp. 488-494
-
-
Couillault, C.1
Pujol, N.2
Reboul, J.3
Sabatier, L.4
Guichou, J.F.5
Kohara, Y.6
Ewbank, J.J.7
-
12
-
-
37849004968
-
A conserved Toll-like receptor is required for Caenorhabditis elegans innate immunity
-
Tenor, J. L., and A. Aballay. 2008. A conserved Toll-like receptor is required for Caenorhabditis elegans innate immunity. EMBO Rep. 9: 103-109.
-
(2008)
EMBO Rep.
, vol.9
, pp. 103-109
-
-
Tenor, J.L.1
Aballay, A.2
-
13
-
-
33748871187
-
The human adaptor SARM negatively regulates adaptor protein TRIF-dependent Toll-like receptor signaling
-
Carty, M., R. Goodbody, M. Schröder, J. Stack, P. N. Moynagh, and A. G. Bowie. 2006. The human adaptor SARM negatively regulates adaptor protein TRIF-dependent Toll-like receptor signaling. Nat. Immunol. 7: 1074-1081.
-
(2006)
Nat. Immunol.
, vol.7
, pp. 1074-1081
-
-
Carty, M.1
Goodbody, R.2
Schröder, M.3
Stack, J.4
Moynagh, P.N.5
Bowie, A.G.6
-
14
-
-
38949205955
-
SARM: A novel Toll-like receptor adaptor, is functionally conserved from arthropod to human
-
Belinda, L. W., W. X. Wei, B. T. Hanh, L. X. Lei, H. Bow, and D. J. Ling. 2008. SARM: a novel Toll-like receptor adaptor, is functionally conserved from arthropod to human. Mol. Immunol. 45: 1732-1742.
-
(2008)
Mol. Immunol.
, vol.45
, pp. 1732-1742
-
-
Belinda, L.W.1
Wei, W.X.2
Hanh, B.T.3
Lei, L.X.4
Bow, H.5
Ling, D.J.6
-
15
-
-
34548424488
-
MyD88-5 links mitochondria, microtubules, and JNK3 in neurons and regulates neuronal survival
-
Kim, Y., P. Zhou, L. Qian, J. Z. Chuang, J. Lee, C. Li, C. Iadecola, C. Nathan, and A. Ding. 2007. MyD88-5 links mitochondria, microtubules, and JNK3 in neurons and regulates neuronal survival. J. Exp. Med. 204: 2063-2074.
-
(2007)
J. Exp. Med.
, vol.204
, pp. 2063-2074
-
-
Kim, Y.1
Zhou, P.2
Qian, L.3
Chuang, J.Z.4
Lee, J.5
Li, C.6
Iadecola, C.7
Nathan, C.8
Ding, A.9
-
16
-
-
69449098052
-
The immune adaptor molecule SARM modulates tumor necrosis factor alpha production and microglia activation in the brainstem and restricts West Nile Virus pathogenesis
-
Szretter, K. J., M. A. Samuel, S. Gilfillan, A. Fuchs, M. Colonna, and M. S. Diamond. 2009. The immune adaptor molecule SARM modulates tumor necrosis factor alpha production and microglia activation in the brainstem and restricts West Nile Virus pathogenesis. J. Virol. 83: 9329-9338.
-
(2009)
J. Virol.
, vol.83
, pp. 9329-9338
-
-
Szretter, K.J.1
Samuel, M.A.2
Gilfillan, S.3
Fuchs, A.4
Colonna, M.5
Diamond, M.S.6
-
17
-
-
0032619101
-
Wholemount in situ hybridization to amphioxus embryos
-
Holland, P. W. 1999. Wholemount in situ hybridization to amphioxus embryos. Methods Mol. Biol. 97: 641-644.
-
(1999)
Methods Mol. Biol.
, vol.97
, pp. 641-644
-
-
Holland, P.W.1
-
18
-
-
70449717530
-
Genomic and functional uniqueness of the TNF receptor-associated factor gene family in amphioxus, the basal chordate
-
Yuan, S., T. Liu, S. Huang, T. Wu, L. Huang, H. Liu, X. Tao, M. Yang, K. Wu, Y. Yu, et al. 2009. Genomic and functional uniqueness of the TNF receptor-associated factor gene family in amphioxus, the basal chordate. J. Immunol. 183: 4560-4568.
-
(2009)
J. Immunol.
, vol.183
, pp. 4560-4568
-
-
Yuan, S.1
Liu, T.2
Huang, S.3
Wu, T.4
Huang, L.5
Liu, H.6
Tao, X.7
Yang, M.8
Wu, K.9
Yu, Y.10
-
19
-
-
39549085742
-
Human prohibitin 1 maintains the organization and stability of the mitochondrial nucleoids
-
Kasashima, K., M. Sumitani, M. Satoh, and H. Endo. 2008. Human prohibitin 1 maintains the organization and stability of the mitochondrial nucleoids. Exp. Cell Res. 314: 988-996.
-
(2008)
Exp. Cell Res.
, vol.314
, pp. 988-996
-
-
Kasashima, K.1
Sumitani, M.2
Satoh, M.3
Endo, H.4
-
20
-
-
67349276674
-
An amphioxus TLR with dynamic embryonic expression pattern responses to pathogens and activates NF-kappaB pathway via MyD88
-
Yuan, S., S. Huang, W. Zhang, T. Wu, M. Dong, Y. Yu, T. Liu, K. Wu, H. Liu, M. Yang, et al. 2009. An amphioxus TLR with dynamic embryonic expression pattern responses to pathogens and activates NF-kappaB pathway via MyD88. Mol. Immunol. 46: 2348-2356.
-
(2009)
Mol. Immunol.
, vol.46
, pp. 2348-2356
-
-
Yuan, S.1
Huang, S.2
Zhang, W.3
Wu, T.4
Dong, M.5
Yu, Y.6
Liu, T.7
Wu, K.8
Liu, H.9
Yang, M.10
-
21
-
-
36348932904
-
IRAK-2 participates in multiple toll-like receptor signaling pathways to NFkappaB via activation of TRAF6 ubiquitination
-
Keating, S. E., G. M. Maloney, E. M. Moran, and A. G. Bowie. 2007. IRAK-2 participates in multiple toll-like receptor signaling pathways to NFkappaB via activation of TRAF6 ubiquitination. J. Biol. Chem. 282: 33435-33443.
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 33435-33443
-
-
Keating, S.E.1
Maloney, G.M.2
Moran, E.M.3
Bowie, A.G.4
-
22
-
-
4444258208
-
Mal interacts with tumor necrosis factor receptor-associated factor (TRAF)-6 to mediate NF-kappaB activation by toll-like receptor (TLR)-2 and TLR4
-
Mansell, A., E. Brint, J. A. Gould, L. A. O'Neill, and P. J. Hertzog. 2004. Mal interacts with tumor necrosis factor receptor-associated factor (TRAF)-6 to mediate NF-kappaB activation by toll-like receptor (TLR)-2 and TLR4. J. Biol. Chem. 279: 37227-37230.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 37227-37230
-
-
Mansell, A.1
Brint, E.2
Gould, J.A.3
O'Neill, L.A.4
Hertzog, P.J.5
-
23
-
-
12144283454
-
AToll-interleukin 1 repeat protein at the synapse specifies asymmetric odorant receptor expression via ASK1 MAPKKK signaling
-
Chuang, C. F., and C. I. Bargmann. 2005. AToll-interleukin 1 repeat protein at the synapse specifies asymmetric odorant receptor expression via ASK1 MAPKKK signaling. Genes Dev. 19: 270-281.
-
(2005)
Genes Dev.
, vol.19
, pp. 270-281
-
-
Chuang, C.F.1
Bargmann, C.I.2
-
24
-
-
38449116840
-
Studies of SARM1 uncover similarities between immune and neuronal responses to danger
-
Dalod, M. 2007. Studies of SARM1 uncover similarities between immune and neuronal responses to danger. Sci. STKE 2007: pe73.
-
(2007)
Sci. STKE
, vol.2007
-
-
Dalod, M.1
-
25
-
-
33746287716
-
Using non-mammalian hosts to study fungal virulence and host defense
-
Fuchs, B. B., and E. Mylonakis. 2006. Using non-mammalian hosts to study fungal virulence and host defense. Curr. Opin. Microbiol. 9: 346-351.
-
(2006)
Curr. Opin. Microbiol.
, vol.9
, pp. 346-351
-
-
Fuchs, B.B.1
Mylonakis, E.2
-
26
-
-
34748826813
-
Caenorhabditis elegans pgp-5 is involved in resistance to bacterial infection and heavy metal and its regulation requires TIR-1 and a p38 map kinase cascade
-
Kurz, C. L., M. Shapira, K. Chen, D. L. Baillie, and M. W. Tan. 2007. Caenorhabditis elegans pgp-5 is involved in resistance to bacterial infection and heavy metal and its regulation requires TIR-1 and a p38 map kinase cascade. Biochem. Biophys. Res. Commun. 363: 438-443.
-
(2007)
Biochem. Biophys. Res. Commun.
, vol.363
, pp. 438-443
-
-
Kurz, C.L.1
Shapira, M.2
Chen, K.3
Baillie, D.L.4
Tan, M.W.5
-
27
-
-
46449138598
-
Genomic analysis of the immune gene repertoire of amphioxus reveals extraordinary innate complexity and diversity
-
DOI 10.1101/gr.069674.107
-
Huang, S., S. Yuan, L. Guo, Y. Yu, J. Li, T. Wu, T. Liu, M. Yang, K. Wu, H. Liu, et al. 2008. Genomic analysis of the immune gene repertoire of amphioxus reveals extraordinary innate complexity and diversity. Genome Res. 18: 1112-1126. (Pubitemid 351931162)
-
(2008)
Genome Research
, vol.18
, Issue.7
, pp. 1112-1126
-
-
Huang, S.1
Yuan, S.2
Guo, L.3
Yu, Y.4
Li, J.5
Wu, T.6
Liu, T.7
Yang, M.8
Wu, K.9
Liu, H.10
Ge, J.11
Yu, Y.12
Huang, H.13
Dong, M.14
Yu, C.15
Chen, S.16
Xu, A.17
-
28
-
-
67649865588
-
Structural basis for the multiple interactions of the MyD88 TIR domain in TLR4 signaling
-
Ohnishi, H., H. Tochio, Z. Kato, K. E. Orii, A. Li, T. Kimura, H. Hiroaki, N. Kondo, and M. Shirakawa. 2009. Structural basis for the multiple interactions of the MyD88 TIR domain in TLR4 signaling. Proc. Natl. Acad. Sci. USA 106: 10260-10265.
-
(2009)
Proc. Natl. Acad. Sci. USA
, vol.106
, pp. 10260-10265
-
-
Ohnishi, H.1
Tochio, H.2
Kato, Z.3
Orii, K.E.4
Li, A.5
Kimura, T.6
Hiroaki, H.7
Kondo, N.8
Shirakawa, M.9
-
29
-
-
57049090580
-
NMR studies of a heterotypic Sam-Sam domain association: The interaction between the lipid phosphatase Ship2 and the EphA2 receptor
-
Leone, M., J. Cellitti, and M. Pellecchia. 2008. NMR studies of a heterotypic Sam-Sam domain association: the interaction between the lipid phosphatase Ship2 and the EphA2 receptor. Biochemistry 47: 12721-12728.
-
(2008)
Biochemistry
, vol.47
, pp. 12721-12728
-
-
Leone, M.1
Cellitti, J.2
Pellecchia, M.3
-
30
-
-
54049133340
-
The RING domain and first zinc finger of TRAF6 coordinate signaling by interleukin-1, lipopolysaccharide, and RANKL
-
Lamothe, B., A. D. Campos, W. K. Webster, A. Gopinathan, L. Hur, and B. G. Darnay. 2008. The RING domain and first zinc finger of TRAF6 coordinate signaling by interleukin-1, lipopolysaccharide, and RANKL. J. Biol. Chem. 283: 24871-24880.
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 24871-24880
-
-
Lamothe, B.1
Campos, A.D.2
Webster, W.K.3
Gopinathan, A.4
Hur, L.5
Darnay, B.G.6
-
31
-
-
53049104824
-
TLR-4, IL-1R and TNF-R signaling to NF-kappaB: Variations on a common theme
-
Verstrepen, L., T. Bekaert, T. L. Chau, J. Tavernier, A. Chariot, and R. Beyaert. 2008. TLR-4, IL-1R and TNF-R signaling to NF-kappaB: variations on a common theme. Cell. Mol. Life Sci. 65: 2964-2978.
-
(2008)
Cell. Mol. Life Sci.
, vol.65
, pp. 2964-2978
-
-
Verstrepen, L.1
Bekaert, T.2
Chau, T.L.3
Tavernier, J.4
Chariot, A.5
Beyaert, R.6
|