-
1
-
-
78650903043
-
Expanding role of ubiquitination in NF-kappaB signaling
-
Liu S., Chen Z.J. Expanding role of ubiquitination in NF-kappaB signaling. Cell Res 2011, 21:6-21.
-
(2011)
Cell Res
, vol.21
, pp. 6-21
-
-
Liu, S.1
Chen, Z.J.2
-
2
-
-
59649086030
-
Nonproteolytic functions of ubiquitin in cell signaling
-
Chen Z.J., Sun L.J. Nonproteolytic functions of ubiquitin in cell signaling. Mol Cell 2009, 33:275-286.
-
(2009)
Mol Cell
, vol.33
, pp. 275-286
-
-
Chen, Z.J.1
Sun, L.J.2
-
3
-
-
67650744586
-
The role of ubiquitin in NF-kappaB regulatory pathways
-
Skaug B., Jiang X., Chen Z.J. The role of ubiquitin in NF-kappaB regulatory pathways. Annu Rev Biochem 2009, 78:769-796.
-
(2009)
Annu Rev Biochem
, vol.78
, pp. 769-796
-
-
Skaug, B.1
Jiang, X.2
Chen, Z.J.3
-
5
-
-
38849199203
-
Shared principles in NF-kappaB signaling
-
Hayden M.S., Ghosh S. Shared principles in NF-kappaB signaling. Cell 2008, 132:344-362.
-
(2008)
Cell
, vol.132
, pp. 344-362
-
-
Hayden, M.S.1
Ghosh, S.2
-
6
-
-
0030004897
-
Site-specific phosphorylation of IkappaBalpha by a novel ubiquitination-dependent protein kinase activity
-
Chen Z.J., Parent L., Maniatis T. Site-specific phosphorylation of IkappaBalpha by a novel ubiquitination-dependent protein kinase activity. Cell 1996, 84:853-862.
-
(1996)
Cell
, vol.84
, pp. 853-862
-
-
Chen, Z.J.1
Parent, L.2
Maniatis, T.3
-
7
-
-
0029761275
-
TRAF6 is a signal transducer for interleukin-1
-
Cao Z., Xiong J., Takeuchi M., Kurama T., Goeddel D.V. TRAF6 is a signal transducer for interleukin-1. Nature 1996, 383:443-446.
-
(1996)
Nature
, vol.383
, pp. 443-446
-
-
Cao, Z.1
Xiong, J.2
Takeuchi, M.3
Kurama, T.4
Goeddel, D.V.5
-
8
-
-
10544243364
-
Identification of TRAF6, a novel tumor necrosis factor receptor-associated factor protein that mediates signaling from an amino-terminal domain of the CD40 cytoplasmic region
-
Ishida T., Mizushima S., Azuma S., Kobayashi N., Tojo T., Suzuki K., Aizawa S., Watanabe T., Mosialos G., Kieff E., et al. Identification of TRAF6, a novel tumor necrosis factor receptor-associated factor protein that mediates signaling from an amino-terminal domain of the CD40 cytoplasmic region. J Biol Chem 1996, 271:28745-28748.
-
(1996)
J Biol Chem
, vol.271
, pp. 28745-28748
-
-
Ishida, T.1
Mizushima, S.2
Azuma, S.3
Kobayashi, N.4
Tojo, T.5
Suzuki, K.6
Aizawa, S.7
Watanabe, T.8
Mosialos, G.9
Kieff, E.10
-
9
-
-
0034644474
-
Activation of the IkappaB kinase complex by TRAF6 requires a dimeric ubiquitin-conjugating enzyme complex and a unique polyubiquitin chain
-
Deng L., Wang C., Spencer E., Yang L., Braun A., You J., Slaughter C., Pickart C., Chen Z.J. Activation of the IkappaB kinase complex by TRAF6 requires a dimeric ubiquitin-conjugating enzyme complex and a unique polyubiquitin chain. Cell 2000, 103:351-361.
-
(2000)
Cell
, vol.103
, pp. 351-361
-
-
Deng, L.1
Wang, C.2
Spencer, E.3
Yang, L.4
Braun, A.5
You, J.6
Slaughter, C.7
Pickart, C.8
Chen, Z.J.9
-
10
-
-
0035913278
-
TAK1 is a ubiquitin-dependent kinase of MKK and IKK
-
Wang C., Deng L., Hong M., Akkaraju G.R., Inoue J., Chen Z.J. TAK1 is a ubiquitin-dependent kinase of MKK and IKK. Nature 2001, 412:346-351.
-
(2001)
Nature
, vol.412
, pp. 346-351
-
-
Wang, C.1
Deng, L.2
Hong, M.3
Akkaraju, G.R.4
Inoue, J.5
Chen, Z.J.6
-
11
-
-
70350015537
-
A ubiquitin replacement strategy in human cells reveals distinct mechanisms of IKK activation by TNFalpha and IL-1beta
-
Xu M., Skaug B., Zeng W., Chen Z.J. A ubiquitin replacement strategy in human cells reveals distinct mechanisms of IKK activation by TNFalpha and IL-1beta. Mol Cell 2009, 36:302-314.
-
(2009)
Mol Cell
, vol.36
, pp. 302-314
-
-
Xu, M.1
Skaug, B.2
Zeng, W.3
Chen, Z.J.4
-
12
-
-
59649103156
-
Involvement of linear polyubiquitylation of NEMO in NF-kappaB activation
-
Tokunaga F., Sakata S., Saeki Y., Satomi Y., Kirisako T., Kamei K., Nakagawa T., Kato M., Murata S., Yamaoka S., et al. Involvement of linear polyubiquitylation of NEMO in NF-kappaB activation. Nat Cell Biol 2009, 11:123-132.
-
(2009)
Nat Cell Biol
, vol.11
, pp. 123-132
-
-
Tokunaga, F.1
Sakata, S.2
Saeki, Y.3
Satomi, Y.4
Kirisako, T.5
Kamei, K.6
Nakagawa, T.7
Kato, M.8
Murata, S.9
Yamaoka, S.10
-
13
-
-
79953237668
-
SHARPIN is a component of the NF-kappaB-activating linear ubiquitin chain assembly complex
-
Tokunaga F., Nakagawa T., Nakahara M., Saeki Y., Taniguchi M., Sakata S., Tanaka K., Nakano H., Iwai K. SHARPIN is a component of the NF-kappaB-activating linear ubiquitin chain assembly complex. Nature 2011, 471:633-636.
-
(2011)
Nature
, vol.471
, pp. 633-636
-
-
Tokunaga, F.1
Nakagawa, T.2
Nakahara, M.3
Saeki, Y.4
Taniguchi, M.5
Sakata, S.6
Tanaka, K.7
Nakano, H.8
Iwai, K.9
-
14
-
-
79953240109
-
Linear ubiquitination prevents inflammation and regulates immune signalling
-
Gerlach B., Cordier S.M., Schmukle A.C., Emmerich C.H., Rieser E., Haas T.L., Webb A.I., Rickard J.A., Anderton H., Wong W.W., et al. Linear ubiquitination prevents inflammation and regulates immune signalling. Nature 2011, 471:591-596.
-
(2011)
Nature
, vol.471
, pp. 591-596
-
-
Gerlach, B.1
Cordier, S.M.2
Schmukle, A.C.3
Emmerich, C.H.4
Rieser, E.5
Haas, T.L.6
Webb, A.I.7
Rickard, J.A.8
Anderton, H.9
Wong, W.W.10
-
15
-
-
79953239980
-
SHARPIN forms a linear ubiquitin ligase complex regulating NF-kappaB activity and apoptosis
-
Ikeda F., Deribe Y.L., Skanland S.S., Stieglitz B., Grabbe C., Franz-Wachtel M., van Wijk S.J., Goswami P., Nagy V., Terzic J., et al. SHARPIN forms a linear ubiquitin ligase complex regulating NF-kappaB activity and apoptosis. Nature 2011, 471:637-641.
-
(2011)
Nature
, vol.471
, pp. 637-641
-
-
Ikeda, F.1
Deribe, Y.L.2
Skanland, S.S.3
Stieglitz, B.4
Grabbe, C.5
Franz-Wachtel, M.6
van Wijk, S.J.7
Goswami, P.8
Nagy, V.9
Terzic, J.10
-
16
-
-
84869429707
-
Immunodeficiency, autoinflammation and amylopectinosis in humans with inherited HOIL-1 and LUBAC deficiency
-
Boisson B., Laplantine E., Prando C., Giliani S., Israelsson E., Xu Z., Abhyankar A., Israel L., Trevejo-Nunez G., Bogunovic D., et al. Immunodeficiency, autoinflammation and amylopectinosis in humans with inherited HOIL-1 and LUBAC deficiency. Nat Immunol 2012, 13:1178-1186.
-
(2012)
Nat Immunol
, vol.13
, pp. 1178-1186
-
-
Boisson, B.1
Laplantine, E.2
Prando, C.3
Giliani, S.4
Israelsson, E.5
Xu, Z.6
Abhyankar, A.7
Israel, L.8
Trevejo-Nunez, G.9
Bogunovic, D.10
-
17
-
-
84862761186
-
Diverse ubiquitin signaling in NF-kappaB activation
-
Iwai K. Diverse ubiquitin signaling in NF-kappaB activation. Trends Cell Biol 2012, 22:355-364.
-
(2012)
Trends Cell Biol
, vol.22
, pp. 355-364
-
-
Iwai, K.1
-
18
-
-
33645703930
-
Sensing of Lys 63-linked polyubiquitination by NEMO is a key event in NF-kappaB activation [corrected]
-
Wu C.J., Conze D.B., Li T., Srinivasula S.M., Ashwell J.D. Sensing of Lys 63-linked polyubiquitination by NEMO is a key event in NF-kappaB activation [corrected]. Nat Cell Biol 2006, 8:398-406.
-
(2006)
Nat Cell Biol
, vol.8
, pp. 398-406
-
-
Wu, C.J.1
Conze, D.B.2
Li, T.3
Srinivasula, S.M.4
Ashwell, J.D.5
-
19
-
-
70350020147
-
NEMO specifically recognizes K63-linked poly-ubiquitin chains through a new bipartite ubiquitin-binding domain
-
Laplantine E., Fontan E., Chiaravalli J., Lopez T., Lakisic G., Veron M., Agou F., Israel A. NEMO specifically recognizes K63-linked poly-ubiquitin chains through a new bipartite ubiquitin-binding domain. EMBO J 2009, 28:2885-2895.
-
(2009)
EMBO J
, vol.28
, pp. 2885-2895
-
-
Laplantine, E.1
Fontan, E.2
Chiaravalli, J.3
Lopez, T.4
Lakisic, G.5
Veron, M.6
Agou, F.7
Israel, A.8
-
20
-
-
62549155321
-
Specific recognition of linear ubiquitin chains by NEMO is important for NF-kappaB activation
-
Rahighi S., Ikeda F., Kawasaki M., Akutsu M., Suzuki N., Kato R., Kensche T., Uejima T., Bloor S., Komander D., et al. Specific recognition of linear ubiquitin chains by NEMO is important for NF-kappaB activation. Cell 2009, 136:1098-1109.
-
(2009)
Cell
, vol.136
, pp. 1098-1109
-
-
Rahighi, S.1
Ikeda, F.2
Kawasaki, M.3
Akutsu, M.4
Suzuki, N.5
Kato, R.6
Kensche, T.7
Uejima, T.8
Bloor, S.9
Komander, D.10
-
21
-
-
79960419007
-
NF-kappaB essential modulator (NEMO) interaction with linear and lys-63 ubiquitin chains contributes to NF-kappaB activation
-
Hadian K., Griesbach R.A., Dornauer S., Wanger T.M., Nagel D., Metlitzky M., Beisker W., Schmidt-Supprian M., Krappmann D. NF-kappaB essential modulator (NEMO) interaction with linear and lys-63 ubiquitin chains contributes to NF-kappaB activation. J Biol Chem 2011, 286:26107-26117.
-
(2011)
J Biol Chem
, vol.286
, pp. 26107-26117
-
-
Hadian, K.1
Griesbach, R.A.2
Dornauer, S.3
Wanger, T.M.4
Nagel, D.5
Metlitzky, M.6
Beisker, W.7
Schmidt-Supprian, M.8
Krappmann, D.9
-
22
-
-
33646034316
-
Activation of IKK by TNFalpha requires site-specific ubiquitination of RIP1 and polyubiquitin binding by NEMO
-
Ea C.K., Deng L., Xia Z.P., Pineda G., Chen Z.J. Activation of IKK by TNFalpha requires site-specific ubiquitination of RIP1 and polyubiquitin binding by NEMO. Mol Cell 2006, 22:245-257.
-
(2006)
Mol Cell
, vol.22
, pp. 245-257
-
-
Ea, C.K.1
Deng, L.2
Xia, Z.P.3
Pineda, G.4
Chen, Z.J.5
-
23
-
-
78650300883
-
C-IAP1 and UbcH5 promote K11-linked polyubiquitination of RIP1 in TNF signalling
-
Dynek J.N., Goncharov T., Dueber E.C., Fedorova A.V., Izrael-Tomasevic A., Phu L., Helgason E., Fairbrother W.J., Deshayes K., Kirkpatrick D.S., et al. c-IAP1 and UbcH5 promote K11-linked polyubiquitination of RIP1 in TNF signalling. EMBO J 2010, 29:4198-4209.
-
(2010)
EMBO J
, vol.29
, pp. 4198-4209
-
-
Dynek, J.N.1
Goncharov, T.2
Dueber, E.C.3
Fedorova, A.V.4
Izrael-Tomasevic, A.5
Phu, L.6
Helgason, E.7
Fairbrother, W.J.8
Deshayes, K.9
Kirkpatrick, D.S.10
-
24
-
-
33744951304
-
Ubiquitination of RIP is required for tumor necrosis factor alpha-induced NF-kappaB activation
-
Li H., Kobayashi M., Blonska M., You Y., Lin X. Ubiquitination of RIP is required for tumor necrosis factor alpha-induced NF-kappaB activation. J Biol Chem 2006, 281:13636-13643.
-
(2006)
J Biol Chem
, vol.281
, pp. 13636-13643
-
-
Li, H.1
Kobayashi, M.2
Blonska, M.3
You, Y.4
Lin, X.5
-
25
-
-
76749132616
-
RIPK1 is not essential for TNFR1-induced activation of NF-kappaB
-
Wong W.W., Gentle I.E., Nachbur U., Anderton H., Vaux D.L., Silke J. RIPK1 is not essential for TNFR1-induced activation of NF-kappaB. Cell Death Differ 2010, 17:482-487.
-
(2010)
Cell Death Differ
, vol.17
, pp. 482-487
-
-
Wong, W.W.1
Gentle, I.E.2
Nachbur, U.3
Anderton, H.4
Vaux, D.L.5
Silke, J.6
-
26
-
-
69949093459
-
Direct activation of protein kinases by unanchored polyubiquitin chains
-
Xia Z.P., Sun L., Chen X., Pineda G., Jiang X., Adhikari A., Zeng W., Chen Z.J. Direct activation of protein kinases by unanchored polyubiquitin chains. Nature 2009, 461:114-119.
-
(2009)
Nature
, vol.461
, pp. 114-119
-
-
Xia, Z.P.1
Sun, L.2
Chen, X.3
Pineda, G.4
Jiang, X.5
Adhikari, A.6
Zeng, W.7
Chen, Z.J.8
-
27
-
-
81355150892
-
Direct, noncatalytic mechanism of IKK inhibition by A20
-
Skaug B., Chen J., Du F., He J., Ma A., Chen Z.J. Direct, noncatalytic mechanism of IKK inhibition by A20. Mol Cell 2011, 44:559-571.
-
(2011)
Mol Cell
, vol.44
, pp. 559-571
-
-
Skaug, B.1
Chen, J.2
Du, F.3
He, J.4
Ma, A.5
Chen, Z.J.6
-
28
-
-
84867025024
-
Ubiquitination and phosphorylation in the regulation of NOD2 signaling and NOD2-mediated disease
-
Tigno-Aranjuez J.T., Abbott D.W. Ubiquitination and phosphorylation in the regulation of NOD2 signaling and NOD2-mediated disease. Biochim Biophys Acta 2012, 1823:2022-2028.
-
(2012)
Biochim Biophys Acta
, vol.1823
, pp. 2022-2028
-
-
Tigno-Aranjuez, J.T.1
Abbott, D.W.2
-
29
-
-
84655176306
-
The role of ubiquitylation in immune defence and pathogen evasion
-
Jiang X., Chen Z.J. The role of ubiquitylation in immune defence and pathogen evasion. Nat Rev Immunol 2011, 12:35-48.
-
(2011)
Nat Rev Immunol
, vol.12
, pp. 35-48
-
-
Jiang, X.1
Chen, Z.J.2
-
30
-
-
34247341367
-
TRIM25 RING-finger E3 ubiquitin ligase is essential for RIG-I-mediated antiviral activity
-
Gack M.U., Shin Y.C., Joo C.H., Urano T., Liang C., Sun L., Takeuchi O., Akira S., Chen Z., Inoue S., et al. TRIM25 RING-finger E3 ubiquitin ligase is essential for RIG-I-mediated antiviral activity. Nature 2007, 446:916-920.
-
(2007)
Nature
, vol.446
, pp. 916-920
-
-
Gack, M.U.1
Shin, Y.C.2
Joo, C.H.3
Urano, T.4
Liang, C.5
Sun, L.6
Takeuchi, O.7
Akira, S.8
Chen, Z.9
Inoue, S.10
-
31
-
-
78650189572
-
The ubiquitin ligase Riplet is essential for RIG-I-dependent innate immune responses to RNA virus infection
-
Oshiumi H., Miyashita M., Inoue N., Okabe M., Matsumoto M., Seya T. The ubiquitin ligase Riplet is essential for RIG-I-dependent innate immune responses to RNA virus infection. Cell Host Microbe 2010, 8:496-509.
-
(2010)
Cell Host Microbe
, vol.8
, pp. 496-509
-
-
Oshiumi, H.1
Miyashita, M.2
Inoue, N.3
Okabe, M.4
Matsumoto, M.5
Seya, T.6
-
32
-
-
77951708374
-
Reconstitution of the RIG-I pathway reveals a signaling role of unanchored polyubiquitin chains in innate immunity
-
Zeng W., Sun L., Jiang X., Chen X., Hou F., Adhikari A., Xu M., Chen Z.J. Reconstitution of the RIG-I pathway reveals a signaling role of unanchored polyubiquitin chains in innate immunity. Cell 2010, 141:315-330.
-
(2010)
Cell
, vol.141
, pp. 315-330
-
-
Zeng, W.1
Sun, L.2
Jiang, X.3
Chen, X.4
Hou, F.5
Adhikari, A.6
Xu, M.7
Chen, Z.J.8
-
33
-
-
84862994793
-
Ubiquitin-induced oligomerization of the RNA sensors RIG-I and MDA5 activates antiviral innate immune response
-
Jiang X., Kinch L.N., Brautigam C.A., Chen X., Du F., Grishin N.V., Chen Z.J. Ubiquitin-induced oligomerization of the RNA sensors RIG-I and MDA5 activates antiviral innate immune response. Immunity 2012, 36:959-973.
-
(2012)
Immunity
, vol.36
, pp. 959-973
-
-
Jiang, X.1
Kinch, L.N.2
Brautigam, C.A.3
Chen, X.4
Du, F.5
Grishin, N.V.6
Chen, Z.J.7
-
34
-
-
3242876747
-
Cyclophilin A retrotransposition into TRIM5 explains owl monkey resistance to HIV-1
-
Sayah D.M., Sokolskaja E., Berthoux L., Luban J. Cyclophilin A retrotransposition into TRIM5 explains owl monkey resistance to HIV-1. Nature 2004, 430:569-573.
-
(2004)
Nature
, vol.430
, pp. 569-573
-
-
Sayah, D.M.1
Sokolskaja, E.2
Berthoux, L.3
Luban, J.4
-
35
-
-
1542288934
-
The cytoplasmic body component TRIM5alpha restricts HIV-1 infection in Old World monkeys
-
Stremlau M., Owens C.M., Perron M.J., Kiessling M., Autissier P., Sodroski J. The cytoplasmic body component TRIM5alpha restricts HIV-1 infection in Old World monkeys. Nature 2004, 427:848-853.
-
(2004)
Nature
, vol.427
, pp. 848-853
-
-
Stremlau, M.1
Owens, C.M.2
Perron, M.J.3
Kiessling, M.4
Autissier, P.5
Sodroski, J.6
-
36
-
-
79955377543
-
TRIM5 is an innate immune sensor for the retrovirus capsid lattice
-
Pertel T., Hausmann S., Morger D., Zuger S., Guerra J., Lascano J., Reinhard C., Santoni F.A., Uchil P.D., Chatel L., et al. TRIM5 is an innate immune sensor for the retrovirus capsid lattice. Nature 2011, 472:361-365.
-
(2011)
Nature
, vol.472
, pp. 361-365
-
-
Pertel, T.1
Hausmann, S.2
Morger, D.3
Zuger, S.4
Guerra, J.5
Lascano, J.6
Reinhard, C.7
Santoni, F.A.8
Uchil, P.D.9
Chatel, L.10
-
37
-
-
84862818454
-
The Shigella flexneri effector OspI deamidates UBC13 to dampen the inflammatory response
-
Sanada T., Kim M., Mimuro H., Suzuki M., Ogawa M., Oyama A., Ashida H., Kobayashi T., Koyama T., Nagai S., et al. The Shigella flexneri effector OspI deamidates UBC13 to dampen the inflammatory response. Nature 2012, 483:623-626.
-
(2012)
Nature
, vol.483
, pp. 623-626
-
-
Sanada, T.1
Kim, M.2
Mimuro, H.3
Suzuki, M.4
Ogawa, M.5
Oyama, A.6
Ashida, H.7
Kobayashi, T.8
Koyama, T.9
Nagai, S.10
-
38
-
-
84855764312
-
Cysteine methylation disrupts ubiquitin-chain sensing in NF-kappaB activation
-
Zhang L., Ding X., Cui J., Xu H., Chen J., Gong Y.N., Hu L., Zhou Y., Ge J., Lu Q., et al. Cysteine methylation disrupts ubiquitin-chain sensing in NF-kappaB activation. Nature 2012, 481:204-208.
-
(2012)
Nature
, vol.481
, pp. 204-208
-
-
Zhang, L.1
Ding, X.2
Cui, J.3
Xu, H.4
Chen, J.5
Gong, Y.N.6
Hu, L.7
Zhou, Y.8
Ge, J.9
Lu, Q.10
-
39
-
-
84867898782
-
A20: linking a complex regulator of ubiquitylation to immunity and human disease
-
Ma A., Malynn B.A. A20: linking a complex regulator of ubiquitylation to immunity and human disease. Nat Rev Immunol 2012, 12:774-785.
-
(2012)
Nat Rev Immunol
, vol.12
, pp. 774-785
-
-
Ma, A.1
Malynn, B.A.2
-
40
-
-
0034730713
-
Failure to regulate TNF-induced NF-kappaB and cell death responses in A20-deficient mice
-
Lee E.G., Boone D.L., Chai S., Libby S.L., Chien M., Lodolce J.P., Ma A. Failure to regulate TNF-induced NF-kappaB and cell death responses in A20-deficient mice. Science 2000, 289:2350-2354.
-
(2000)
Science
, vol.289
, pp. 2350-2354
-
-
Lee, E.G.1
Boone, D.L.2
Chai, S.3
Libby, S.L.4
Chien, M.5
Lodolce, J.P.6
Ma, A.7
-
41
-
-
50449103533
-
Multiple polymorphisms in the TNFAIP3 region are independently associated with systemic lupus erythematosus
-
Musone S.L., Taylor K.E., Lu T.T., Nititham J., Ferreira R.C., Ortmann W., Shifrin N., Petri M.A., Kamboh M.I., Manzi S., et al. Multiple polymorphisms in the TNFAIP3 region are independently associated with systemic lupus erythematosus. Nat Genet 2008, 40:1062-1064.
-
(2008)
Nat Genet
, vol.40
, pp. 1062-1064
-
-
Musone, S.L.1
Taylor, K.E.2
Lu, T.T.3
Nititham, J.4
Ferreira, R.C.5
Ortmann, W.6
Shifrin, N.7
Petri, M.A.8
Kamboh, M.I.9
Manzi, S.10
-
42
-
-
84863596116
-
A20 (Tnfaip3) deficiency in myeloid cells protects against influenza A virus infection
-
Maelfait J., Roose K., Bogaert P., Sze M., Saelens X., Pasparakis M., Carpentier I., van Loo G., Beyaert R. A20 (Tnfaip3) deficiency in myeloid cells protects against influenza A virus infection. PLoS Pathog 2012, 8:e1002570.
-
(2012)
PLoS Pathog
, vol.8
-
-
Maelfait, J.1
Roose, K.2
Bogaert, P.3
Sze, M.4
Saelens, X.5
Pasparakis, M.6
Carpentier, I.7
van Loo, G.8
Beyaert, R.9
-
43
-
-
77955917771
-
The ubiquitin modifying enzyme A20 restricts B cell survival and prevents autoimmunity
-
Tavares R.M., Turer E.E., Liu C.L., Advincula R., Scapini P., Rhee L., Barrera J., Lowell C.A., Utz P.J., Malynn B.A., et al. The ubiquitin modifying enzyme A20 restricts B cell survival and prevents autoimmunity. Immunity 2010, 33:181-191.
-
(2010)
Immunity
, vol.33
, pp. 181-191
-
-
Tavares, R.M.1
Turer, E.E.2
Liu, C.L.3
Advincula, R.4
Scapini, P.5
Rhee, L.6
Barrera, J.7
Lowell, C.A.8
Utz, P.J.9
Malynn, B.A.10
-
44
-
-
3943054838
-
De-ubiquitination and ubiquitin ligase domains of A20 downregulate NF-kappaB signalling
-
Wertz I.E., O'Rourke K.M., Zhou H., Eby M., Aravind L., Seshagiri S., Wu P., Wiesmann C., Baker R., Boone D.L., et al. De-ubiquitination and ubiquitin ligase domains of A20 downregulate NF-kappaB signalling. Nature 2004, 430:694-699.
-
(2004)
Nature
, vol.430
, pp. 694-699
-
-
Wertz, I.E.1
O'Rourke, K.M.2
Zhou, H.3
Eby, M.4
Aravind, L.5
Seshagiri, S.6
Wu, P.7
Wiesmann, C.8
Baker, R.9
Boone, D.L.10
-
45
-
-
78649292467
-
Ubiquitin binding to A20 ZnF4 is required for modulation of NF-kappaB signaling
-
Bosanac I., Wertz I.E., Pan B., Yu C., Kusam S., Lam C., Phu L., Phung Q., Maurer B., Arnott D., et al. Ubiquitin binding to A20 ZnF4 is required for modulation of NF-kappaB signaling. Mol Cell 2010, 40:548-557.
-
(2010)
Mol Cell
, vol.40
, pp. 548-557
-
-
Bosanac, I.1
Wertz, I.E.2
Pan, B.3
Yu, C.4
Kusam, S.5
Lam, C.6
Phu, L.7
Phung, Q.8
Maurer, B.9
Arnott, D.10
-
46
-
-
77649225756
-
Inhibition of NF-kappaB signaling by A20 through disruption of ubiquitin enzyme complexes
-
Shembade N., Ma A., Harhaj E.W. Inhibition of NF-kappaB signaling by A20 through disruption of ubiquitin enzyme complexes. Science 2010, 327:1135-1139.
-
(2010)
Science
, vol.327
, pp. 1135-1139
-
-
Shembade, N.1
Ma, A.2
Harhaj, E.W.3
-
47
-
-
84867043680
-
Specific recognition of linear polyubiquitin by A20 zinc finger 7 is involved in NF-kappaB regulation
-
Tokunaga F., Nishimasu H., Ishitani R., Goto E., Noguchi T., Mio K., Kamei K., Ma A., Iwai K., Nureki O. Specific recognition of linear polyubiquitin by A20 zinc finger 7 is involved in NF-kappaB regulation. EMBO J 2012, 31:3856-3870.
-
(2012)
EMBO J
, vol.31
, pp. 3856-3870
-
-
Tokunaga, F.1
Nishimasu, H.2
Ishitani, R.3
Goto, E.4
Noguchi, T.5
Mio, K.6
Kamei, K.7
Ma, A.8
Iwai, K.9
Nureki, O.10
-
48
-
-
84867062977
-
A20 inhibits LUBAC-mediated NF-kappaB activation by binding linear polyubiquitin chains via its zinc finger 7
-
Verhelst K., Carpentier I., Kreike M., Meloni L., Verstrepen L., Kensche T., Dikic I., Beyaert R. A20 inhibits LUBAC-mediated NF-kappaB activation by binding linear polyubiquitin chains via its zinc finger 7. EMBO J 2012, 31:3845-3855.
-
(2012)
EMBO J
, vol.31
, pp. 3845-3855
-
-
Verhelst, K.1
Carpentier, I.2
Kreike, M.3
Meloni, L.4
Verstrepen, L.5
Kensche, T.6
Dikic, I.7
Beyaert, R.8
-
49
-
-
34548405689
-
Essential role for TAX1BP1 in the termination of TNF-alpha-, IL-1- and LPS-mediated NF-kappaB and JNK signaling
-
Shembade N., Harhaj N.S., Liebl D.J., Harhaj E.W. Essential role for TAX1BP1 in the termination of TNF-alpha-, IL-1- and LPS-mediated NF-kappaB and JNK signaling. EMBO J 2007, 26:3910-3922.
-
(2007)
EMBO J
, vol.26
, pp. 3910-3922
-
-
Shembade, N.1
Harhaj, N.S.2
Liebl, D.J.3
Harhaj, E.W.4
-
50
-
-
39449083378
-
The E3 ligase Itch negatively regulates inflammatory signaling pathways by controlling the function of the ubiquitin-editing enzyme A20
-
Shembade N., Harhaj N.S., Parvatiyar K., Copeland N.G., Jenkins N.A., Matesic L.E., Harhaj E.W. The E3 ligase Itch negatively regulates inflammatory signaling pathways by controlling the function of the ubiquitin-editing enzyme A20. Nat Immunol 2008, 9:254-262.
-
(2008)
Nat Immunol
, vol.9
, pp. 254-262
-
-
Shembade, N.1
Harhaj, N.S.2
Parvatiyar, K.3
Copeland, N.G.4
Jenkins, N.A.5
Matesic, L.E.6
Harhaj, E.W.7
-
51
-
-
61949220270
-
The ubiquitin-editing enzyme A20 requires RNF11 to downregulate NF-kappaB signalling
-
Shembade N., Parvatiyar K., Harhaj N.S., Harhaj E.W. The ubiquitin-editing enzyme A20 requires RNF11 to downregulate NF-kappaB signalling. EMBO J 2009, 28:513-522.
-
(2009)
EMBO J
, vol.28
, pp. 513-522
-
-
Shembade, N.1
Parvatiyar, K.2
Harhaj, N.S.3
Harhaj, E.W.4
-
52
-
-
80051986818
-
The kinase IKKalpha inhibits activation of the transcription factor NF-kappaB by phosphorylating the regulatory molecule TAX1BP1
-
Shembade N., Pujari R., Harhaj N.S., Abbott D.W., Harhaj E.W. The kinase IKKalpha inhibits activation of the transcription factor NF-kappaB by phosphorylating the regulatory molecule TAX1BP1. Nat Immunol 2011, 12:834-843.
-
(2011)
Nat Immunol
, vol.12
, pp. 834-843
-
-
Shembade, N.1
Pujari, R.2
Harhaj, N.S.3
Abbott, D.W.4
Harhaj, E.W.5
-
53
-
-
18844464056
-
Identification of the familial cylindromatosis tumour-suppressor gene
-
Bignell G.R., Warren W., Seal S., Takahashi M., Rapley E., Barfoot R., Green H., Brown C., Biggs P.J., Lakhani S.R., et al. Identification of the familial cylindromatosis tumour-suppressor gene. Nat Genet 2000, 25:160-165.
-
(2000)
Nat Genet
, vol.25
, pp. 160-165
-
-
Bignell, G.R.1
Warren, W.2
Seal, S.3
Takahashi, M.4
Rapley, E.5
Barfoot, R.6
Green, H.7
Brown, C.8
Biggs, P.J.9
Lakhani, S.R.10
-
54
-
-
0041967054
-
The tumour suppressor CYLD negatively regulates NF-kappaB signalling by deubiquitination
-
Kovalenko A., Chable-Bessia C., Cantarella G., Israel A., Wallach D., Courtois G. The tumour suppressor CYLD negatively regulates NF-kappaB signalling by deubiquitination. Nature 2003, 424:801-805.
-
(2003)
Nature
, vol.424
, pp. 801-805
-
-
Kovalenko, A.1
Chable-Bessia, C.2
Cantarella, G.3
Israel, A.4
Wallach, D.5
Courtois, G.6
-
55
-
-
0042467558
-
CYLD is a deubiquitinating enzyme that negatively regulates NF-kappaB activation by TNFR family members
-
Trompouki E., Hatzivassiliou E., Tsichritzis T., Farmer H., Ashworth A., Mosialos G. CYLD is a deubiquitinating enzyme that negatively regulates NF-kappaB activation by TNFR family members. Nature 2003, 424:793-796.
-
(2003)
Nature
, vol.424
, pp. 793-796
-
-
Trompouki, E.1
Hatzivassiliou, E.2
Tsichritzis, T.3
Farmer, H.4
Ashworth, A.5
Mosialos, G.6
-
56
-
-
0042467554
-
Loss of the cylindromatosis tumour suppressor inhibits apoptosis by activating NF-kappaB
-
Brummelkamp T.R., Nijman S.M., Dirac A.M., Bernards R. Loss of the cylindromatosis tumour suppressor inhibits apoptosis by activating NF-kappaB. Nature 2003, 424:797-801.
-
(2003)
Nature
, vol.424
, pp. 797-801
-
-
Brummelkamp, T.R.1
Nijman, S.M.2
Dirac, A.M.3
Bernards, R.4
-
57
-
-
57649181391
-
Identification of a molecular signaling network that regulates a cellular necrotic cell death pathway
-
Hitomi J., Christofferson D.E., Ng A., Yao J., Degterev A., Xavier R.J., Yuan J. Identification of a molecular signaling network that regulates a cellular necrotic cell death pathway. Cell 2008, 135:1311-1323.
-
(2008)
Cell
, vol.135
, pp. 1311-1323
-
-
Hitomi, J.1
Christofferson, D.E.2
Ng, A.3
Yao, J.4
Degterev, A.5
Xavier, R.J.6
Yuan, J.7
-
58
-
-
80052049291
-
Ubiquitin-specific peptidase 20 targets TRAF6 and human T cell leukemia virus type 1 tax to negatively regulate NF-kappaB signaling
-
Yasunaga J., Lin F.C., Lu X., Jeang K.T. Ubiquitin-specific peptidase 20 targets TRAF6 and human T cell leukemia virus type 1 tax to negatively regulate NF-kappaB signaling. J Virol 2011, 85:6212-6219.
-
(2011)
J Virol
, vol.85
, pp. 6212-6219
-
-
Yasunaga, J.1
Lin, F.C.2
Lu, X.3
Jeang, K.T.4
-
59
-
-
84874332545
-
USP2a negatively regulates IL-1beta- and virus-induced NF-kappaB activation by deubiquitinating TRAF6
-
He X., Li Y., Li C., Liu L.J., Zhang X.D., Liu Y., Shu H.B. USP2a negatively regulates IL-1beta- and virus-induced NF-kappaB activation by deubiquitinating TRAF6. J Mol Cell Biol 2012, 10.1093/jmcb/mjs024.
-
(2012)
J Mol Cell Biol
-
-
He, X.1
Li, Y.2
Li, C.3
Liu, L.J.4
Zhang, X.D.5
Liu, Y.6
Shu, H.B.7
-
60
-
-
74049114641
-
Ubiquitin-specific peptidase 21 inhibits tumor necrosis factor alpha-induced nuclear factor kappaB activation via binding to and deubiquitinating receptor-interacting protein 1
-
Xu G., Tan X., Wang H., Sun W., Shi Y., Burlingame S., Gu X., Cao G., Zhang T., Qin J., et al. Ubiquitin-specific peptidase 21 inhibits tumor necrosis factor alpha-induced nuclear factor kappaB activation via binding to and deubiquitinating receptor-interacting protein 1. J Biol Chem 2010, 285:969-978.
-
(2010)
J Biol Chem
, vol.285
, pp. 969-978
-
-
Xu, G.1
Tan, X.2
Wang, H.3
Sun, W.4
Shi, Y.5
Burlingame, S.6
Gu, X.7
Cao, G.8
Zhang, T.9
Qin, J.10
-
61
-
-
84859507872
-
Ubiquitin-specific protease 4 mitigates toll-like/interleukin-1 receptor signaling and regulates innate immune activation
-
Zhou F., Zhang X., van Dam H., Ten Dijke P., Huang H., Zhang L. Ubiquitin-specific protease 4 mitigates toll-like/interleukin-1 receptor signaling and regulates innate immune activation. J Biol Chem 2012, 287:11002-11010.
-
(2012)
J Biol Chem
, vol.287
, pp. 11002-11010
-
-
Zhou, F.1
Zhang, X.2
van Dam, H.3
Ten Dijke, P.4
Huang, H.5
Zhang, L.6
-
62
-
-
84857782898
-
Polyubiquitin-sensor proteins reveal localization and linkage-type dependence of cellular ubiquitin signaling
-
Sims J.J., Scavone F., Cooper E.M., Kane L.A., Youle R.J., Boeke J.D., Cohen R.E. Polyubiquitin-sensor proteins reveal localization and linkage-type dependence of cellular ubiquitin signaling. Nat Methods 2012, 9:303-309.
-
(2012)
Nat Methods
, vol.9
, pp. 303-309
-
-
Sims, J.J.1
Scavone, F.2
Cooper, E.M.3
Kane, L.A.4
Youle, R.J.5
Boeke, J.D.6
Cohen, R.E.7
-
63
-
-
84866300942
-
Fluorescence-based sensors to monitor localization and functions of linear and K63-linked ubiquitin chains in cells
-
van Wijk S.J., Fiskin E., Putyrski M., Pampaloni F., Hou J., Wild P., Kensche T., Grecco H.E., Bastiaens P., Dikic I. Fluorescence-based sensors to monitor localization and functions of linear and K63-linked ubiquitin chains in cells. Mol Cell 2012.
-
(2012)
Mol Cell
-
-
van Wijk, S.J.1
Fiskin, E.2
Putyrski, M.3
Pampaloni, F.4
Hou, J.5
Wild, P.6
Kensche, T.7
Grecco, H.E.8
Bastiaens, P.9
Dikic, I.10
-
64
-
-
80054694510
-
Global identification of modular cullin-RING ligase substrates
-
Emanuele M.J., Elia A.E., Xu Q., Thoma C.R., Izhar L., Leng Y., Guo A., Chen Y.N., Rush J., Hsu P.W., et al. Global identification of modular cullin-RING ligase substrates. Cell 2011, 147:459-474.
-
(2011)
Cell
, vol.147
, pp. 459-474
-
-
Emanuele, M.J.1
Elia, A.E.2
Xu, Q.3
Thoma, C.R.4
Izhar, L.5
Leng, Y.6
Guo, A.7
Chen, Y.N.8
Rush, J.9
Hsu, P.W.10
-
65
-
-
78651225388
-
Global analysis of lysine ubiquitination by ubiquitin remnant immunoaffinity profiling
-
Xu G., Paige J.S., Jaffrey S.R. Global analysis of lysine ubiquitination by ubiquitin remnant immunoaffinity profiling. Nat Biotechnol 2010, 28:868-873.
-
(2010)
Nat Biotechnol
, vol.28
, pp. 868-873
-
-
Xu, G.1
Paige, J.S.2
Jaffrey, S.R.3
-
66
-
-
82455179484
-
Systematic and quantitative assessment of the ubiquitin-modified proteome
-
Kim W., Bennett E.J., Huttlin E.L., Guo A., Li J., Possemato A., Sowa M.E., Rad R., Rush J., Comb M.J., et al. Systematic and quantitative assessment of the ubiquitin-modified proteome. Mol Cell 2011, 44:325-340.
-
(2011)
Mol Cell
, vol.44
, pp. 325-340
-
-
Kim, W.1
Bennett, E.J.2
Huttlin, E.L.3
Guo, A.4
Li, J.5
Possemato, A.6
Sowa, M.E.7
Rad, R.8
Rush, J.9
Comb, M.J.10
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