Ubiquitylation of the initiator caspase DREDD is required for innate immune signalling

EMBO Journal

Volumn 31, Issue 12, 2012, Pages 2770-2783

  Meinander, Annika ^a,c   Runchel, Christopher ^a   Tenev, Tencho ^a   Chen, Li ^b   Kim, Chan Hee ^b   Ribeiro, Paulo S ^a,d   Broemer, Meike ^a,e   Leulier, Francois ^a,f   Zvelebil, Marketa ^a   Silverman, Neal ^b   Meier, Pascal ^a  

^a INSTITUTE OF CANCER RESEARCH   (United Kingdom)

^b UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

^c ÅBO AKADEMI UNIVERSITY   (Finland)

^d IMPERIAL CANCER RESEARCH FUND   (United Kingdom)

^e UNIVERSITY OF BONN   (Germany)

^f AIX MARSEILLE UNIVERSITÉ   (France)

Author keywords

caspase; Drosophila; IAP; innate immunity; ubiquitin

Indexed keywords

ACTIN; ALPHA ACTIN; CASPASE; FAS ASSOCIATED DEATH DOMAIN PROTEIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PATTERN RECOGNITION RECEPTOR; PROTEIN DED1; PROTEIN DED2; PROTEIN DIAP2; PROTEIN DREDD; PROTEIN P120; PROTEIN P20; UBIQUITIN; UBIQUITIN PROTEIN LIGASE; UNCLASSIFIED DRUG;

ANIMAL CELL; APOPTOSIS; ARTICLE; BACTERIAL INFECTION; CELL KILLING; CONTROLLED STUDY; DROSOPHILA; ENZYME ACTIVATION; GENE EXPRESSION; GRAM NEGATIVE BACTERIUM; IMMUNOREGULATION; INNATE IMMUNITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN PROCESSING; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; UBIQUITINATION;

ANIMALS; ANTIMICROBIAL CATIONIC PEPTIDES; CARRIER PROTEINS; CASPASES; DROSOPHILA; DROSOPHILA PROTEINS; GENE EXPRESSION REGULATION; GRAM-NEGATIVE BACTERIA; IMMUNITY, INNATE; INHIBITOR OF APOPTOSIS PROTEINS; MODELS, BIOLOGICAL; NF-KAPPA B; TRANSCRIPTION FACTORS; UBIQUITINATION;

NEGIBACTERIA;

EID: 84862189464     PISSN: 02614189     EISSN: 14602075     Source Type: Journal    
DOI: 10.1038/emboj.2012.121     Document Type: Article

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