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Volumn , Issue , 2011, Pages 75-104

Biodistribution and Pharmacokinetics of Nanoprobes

Author keywords

Nanoparticle based technology factors affecting nanoprobe biodistribution and pharmacokinetics, as size, shape, surface functionality coating and charge; Nanoprobe biodistribution and pharmacokinetics nanoprobe toxicity, in biomedical and clinical applications; Theragnostic nanoprobes, and nanoparticle delivery systems therapeutic vehicle with multiple examples approved by FDA for therapy

Indexed keywords


EID: 84886029723     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1002/9780470767047.ch4     Document Type: Chapter
Times cited : (12)

References (183)
  • 1
    • 11144323939 scopus 로고    scopus 로고
    • Quantum dot nanocrystals for in vivo molecular and cellular imaging
    • Smith, A. M.; Gao, X.; Nie, S. Quantum dot nanocrystals for in vivo molecular and cellular imaging. Photochem. Photobiol. 2004, 80, 377-385.
    • (2004) Photochem. Photobiol. , vol.80 , pp. 377-385
    • Smith, A.M.1    Gao, X.2    Nie, S.3
  • 2
    • 20144379798 scopus 로고    scopus 로고
    • Quantum dot bioconjugates for imaging labelling and sensing
    • Medintz, I. L.; Uyeda, H. T.; Goldman, E. R.; Mattoussi, H. Quantum dot bioconjugates for imaging, labelling and sensing. Nat. Mater. 2005, 4, 435-446.
    • (2005) Nat. Mater. , vol.4 , pp. 435-446
    • Medintz, I.L.1    Uyeda, H.T.2    Goldman, E.R.3    Mattoussi, H.4
  • 4
    • 33646145311 scopus 로고    scopus 로고
    • Quantum dot surfaces for use in vivo and in vitro
    • Ballou, B. Quantum dot surfaces for use in vivo and in vitro. Curr. Top. Dev. Biol. 2005, 70, 103-120.
    • (2005) Curr. Top. Dev. Biol. , vol.70 , pp. 103-120
    • Ballou, B.1
  • 5
    • 36349021941 scopus 로고    scopus 로고
    • Single-molecule measurements with a single quantum dot
    • Kaji, N.; Tokeshi, M.; Baba, Y. Single-molecule measurements with a single quantum dot. Chem. Rec. (N.Y.) 2007, 7, 295-304.
    • (2007) Chem. Rec. (N.Y.) , vol.7 , pp. 295-304
    • Kaji, N.1    Tokeshi, M.2    Baba, Y.3
  • 6
    • 3543022686 scopus 로고    scopus 로고
    • In vivo cancer targeting and imaging with semiconductor quantum dots
    • Gao, X.; Cui, Y.; Levenson, R. M.; Chung, L. W.; Nie, S. In vivo cancer targeting and imaging with semiconductor quantum dots. Nat. Biotechnol. 2004, 22, 969-976.
    • (2004) Nat. Biotechnol. , vol.22 , pp. 969-976
    • Gao, X.1    Cui, Y.2    Levenson, R.M.3    Chung, L.W.4    Nie, S.5
  • 8
    • 34247179477 scopus 로고    scopus 로고
    • Magnetic nanoparticles: synthesis protection functionalization and application
    • Lu, A. H.; Salabas, E. L.; Schuth, F. Magnetic nanoparticles: synthesis, protection, functionalization, and application. Angew. Chem. Int. Ed. 2007, 46, 1222-1244.
    • (2007) Angew. Chem. Int. Ed. , vol.46 , pp. 1222-1244
    • Lu, A.H.1    Salabas, E.L.2    Schuth, F.3
  • 9
    • 34249795767 scopus 로고    scopus 로고
    • Recent advances on surface engineering of magnetic iron oxide nanoparticles and their biomedical applications
    • Gupta, A. K.; Naregalkar, R. R.; Vaidya, V. D.; Gupta, M. Recent advances on surface engineering of magnetic iron oxide nanoparticles and their biomedical applications. Nanomedicine (London) 2007, 2, 23-39.
    • (2007) Nanomedicine (London) , vol.2 , pp. 23-39
    • Gupta, A.K.1    Naregalkar, R.R.2    Vaidya, V.D.3    Gupta, M.4
  • 10
    • 27644542061 scopus 로고    scopus 로고
    • Medical application of functionalized magnetic nanoparticles
    • Ito, A.; Shinkai, M.; Honda, H.; Kobayashi, T. Medical application of functionalized magnetic nanoparticles. J. Biosci. Bioeng. 2005, 100, 1-11.
    • (2005) J. Biosci. Bioeng. , vol.100 , pp. 1-11
    • Ito, A.1    Shinkai, M.2    Honda, H.3    Kobayashi, T.4
  • 11
    • 33751410697 scopus 로고    scopus 로고
    • Recent advances in iron oxide nanocrystal technology for medical imaging
    • Corot, C.; Robert, P.; Idee, J. M.; Port, M. Recent advances in iron oxide nanocrystal technology for medical imaging. Adv. Drug Deliv. Rev. 2006, 58, 1471-1504.
    • (2006) Adv. Drug Deliv. Rev. , vol.58 , pp. 1471-1504
    • Corot, C.1    Robert, P.2    Idee, J.M.3    Port, M.4
  • 12
    • 7244256234 scopus 로고    scopus 로고
    • Carbon nanotube electron sources and applications
    • de Jonge, N.; Bonard, J. M. Carbon nanotube electron sources and applications. Philos. Trans. 2004, 362, 2239-2266.
    • (2004) Philos. Trans. , vol.362 , pp. 2239-2266
    • de Jonge, N.1    Bonard, J.M.2
  • 14
    • 67651233657 scopus 로고    scopus 로고
    • Gold nanoparticles in nanomedicine: preparations imaging diagnostics therapies and toxicity
    • Boisselier, E.; Astruc, D. Gold nanoparticles in nanomedicine: preparations, imaging, diagnostics, therapies and toxicity. Chem. Soc. Rev. 2009, 38, 1759-1782.
    • (2009) Chem. Soc. Rev. , vol.38 , pp. 1759-1782
    • Boisselier, E.1    Astruc, D.2
  • 16
    • 0742321804 scopus 로고    scopus 로고
    • Gold nanoparticles: assembly supramolecular chemistry quantumsize- related properties and applications toward biology catalysis and nanotechnology
    • Daniel, M. C.; Astruc, D. Gold nanoparticles: assembly, supramolecular chemistry, quantumsize- related properties, and applications toward biology, catalysis, and nanotechnology. Chem. Rev. 2004, 104, 293-346.
    • (2004) Chem. Rev. , vol.104 , pp. 293-346
    • Daniel, M.C.1    Astruc, D.2
  • 17
    • 37249089714 scopus 로고    scopus 로고
    • Gold nanoparticles: interesting optical properties and recent applications in cancer diagnostics and therapy
    • Huang, X.; Jain, P. K.; El-Sayed, I. H.; El-Sayed, M. A. Gold nanoparticles: interesting optical properties and recent applications in cancer diagnostics and therapy. Nanomedicine (London) 2007, 2, 681-693.
    • (2007) Nanomedicine(London) , vol.2 , pp. 681-693
    • Huang, X.1    Jain, P.K.2    El-Sayed, I.H.3    El-Sayed, M.A.4
  • 18
    • 42449123160 scopus 로고    scopus 로고
    • Past present and future of gold nanoparticles
    • Jennings, T.; Strouse, G. Past, present, and future of gold nanoparticles. Adv. Exp. Med. Biol. 2007, 620, 34-47.
    • (2007) Adv. Exp. Med. Biol. , vol.620 , pp. 34-47
    • Jennings, T.1    Strouse, G.2
  • 21
    • 46749132642 scopus 로고    scopus 로고
    • Multifunctional magnetic nanoparticles for targeted imaging and therapy
    • McCarthy, J. R.; Weissleder, R. Multifunctional magnetic nanoparticles for targeted imaging and therapy. Adv. Drug Deliv. Rev. 2008, 60, 1241-1251.
    • (2008) Adv. Drug Deliv. Rev. , vol.60 , pp. 1241-1251
    • McCarthy, J.R.1    Weissleder, R.2
  • 24
    • 34247475688 scopus 로고    scopus 로고
    • Nanomedicine for drug delivery and imaging: a promising avenue for cancer therapy and diagnosis using targeted functional nanoparticles
    • Liu, Y.; Miyoshi, H.; Nakamura, M. Nanomedicine for drug delivery and imaging: a promising avenue for cancer therapy and diagnosis using targeted functional nanoparticles. Int. J. Cancer 2007, 120, 2527-2537.
    • (2007) Int. J. Cancer , vol.120 , pp. 2527-2537
    • Liu, Y.1    Miyoshi, H.2    Nakamura, M.3
  • 25
    • 34547767133 scopus 로고    scopus 로고
    • Towards the use of nanoparticles in cancer therapy and imaging
    • Pauwels, E. K.; Erba, P. Towards the use of nanoparticles in cancer therapy and imaging. Drug News & Perspect. 2007, 20, 213-220.
    • (2007) Drug News & Perspect. , vol.20 , pp. 213-220
    • Pauwels, E.K.1    Erba, P.2
  • 26
    • 46749142847 scopus 로고    scopus 로고
    • Magnetic nanoparticles in MR imaging and drug delivery
    • Sun, C.; Lee, J. S.; Zhang, M. Magnetic nanoparticles in MR imaging and drug delivery. Adv. Drug Deliv. Rev. 2008, 60, 1252-1265.
    • (2008) Adv. Drug Deliv. Rev. , vol.60 , pp. 1252-1265
    • Sun, C.1    Lee, J.S.2    Zhang, M.3
  • 28
    • 34249803823 scopus 로고    scopus 로고
    • Functionalized gold nanoparticles for drug delivery
    • Han, G.; Ghosh, P.; Rotello, V. M. Functionalized gold nanoparticles for drug delivery. Nanomedicine (London) 2007, 2, 113-123.
    • (2007) Nanomedicine (London) , vol.2 , pp. 113-123
    • Han, G.1    Ghosh, P.2    Rotello, V.M.3
  • 29
    • 42449095051 scopus 로고    scopus 로고
    • Multi-functional gold nanoparticles for drug delivery
    • Han, G.; Ghosh, P.; Rotello, V. M. Multi-functional gold nanoparticles for drug delivery. Adv. Exp. Med. Biol. 2007, 620, 48-56.
    • (2007) Adv. Exp. Med. Biol. , vol.620 , pp. 48-56
    • Han, G.1    Ghosh, P.2    Rotello, V.M.3
  • 31
    • 41649110649 scopus 로고    scopus 로고
    • Imaging in the era of molecular oncology
    • Weissleder, R.; Pittet, M. J. Imaging in the era of molecular oncology. Nature 2008, 452, 580-589.
    • (2008) Nature , vol.452 , pp. 580-589
    • Weissleder, R.1    Pittet, M.J.2
  • 34
    • 0036359767 scopus 로고    scopus 로고
    • Scaling down imaging: molecular mapping of cancer in mice
    • Weissleder, R. Scaling down imaging: molecular mapping of cancer in mice. Nat. Rev. Cancer 2002, 2, 11-19.
    • (2002) Nat. Rev. Cancer , vol.2 , pp. 11-19
    • Weissleder, R.1
  • 35
    • 13844265749 scopus 로고    scopus 로고
    • Molecular imaging in the clinical arena
    • Jaffer, F. A.;Weissleder, R.Molecular imaging in the clinical arena. JAMA 2005, 293, 855-862.
    • (2005) JAMA , vol.293 , pp. 855-862
    • Jaffer, F.A.1    Weissleder, R.2
  • 36
    • 0035318612 scopus 로고    scopus 로고
    • clearer vision for in vivo imaging
    • Weissleder, R. A clearer vision for in vivo imaging. Nat. Biotechnol. 2001, 19, 316-317.
    • (2001) Nat. Biotechnol. , vol.19 , pp. 316-317
    • Weissleder, R.A.1
  • 38
    • 3543022686 scopus 로고    scopus 로고
    • In vivo cancer targeting and imaging with semiconductor quantum dots
    • Gao, X.; Cui, Y.; Levenson, R. M.; Chung, L. W.; Nie, S. In vivo cancer targeting and imaging with semiconductor quantum dots. Nat. Biotechnol. 2004, 22, 969-976.
    • (2004) Nat. Biotechnol. , vol.22 , pp. 969-976
    • Gao, X.1    Cui, Y.2    Levenson, R.M.3    Chung, L.W.4    Nie, S.5
  • 40
    • 46749091612 scopus 로고    scopus 로고
    • Bioconjugated quantum dots for in vivo molecular and cellular imaging
    • Smith, A.M.; Duan, H.; Mohs, A.M.; Nie, S. Bioconjugated quantum dots for in vivo molecular and cellular imaging. Adv. Drug Deliv. Rev. 2008, 60, 1226-1240.
    • (2008) Adv. Drug Deliv. Rev. , vol.60 , pp. 1226-1240
    • Smith, A.M.1    Duan, H.2    Mohs, A.M.3    Nie, S.4
  • 41
  • 46
    • 65249178345 scopus 로고    scopus 로고
    • Carbon nanotubes in biology and medicine: in vitro and in vivo detection imaging and drug delivery
    • Liu, Z.; Tabakman, S.;Welsher, K.; Dai, H. Carbon nanotubes in biology and medicine: in vitro and in vivo detection, imaging and drug delivery. Nano Res. 2009, 2, 85-120.
    • (2009) Nano Res. , vol.2 , pp. 85-120
    • Liu, Z.1    Tabakman, S.2    Welsher, K.3    Dai, H.4
  • 47
    • 33744914356 scopus 로고    scopus 로고
    • Multifunctional molecular carbon materials-from fullerenes to carbon nanotubes
    • Guldi, D. M.; Rahman, G. M.; Sgobba, V.; Ehli, C. Multifunctional molecular carbon materials-from fullerenes to carbon nanotubes. Chem. Soc. Rev. 2006, 35, 471-487.
    • (2006) Chem. Soc. Rev. , vol.35 , pp. 471-487
    • Guldi, D.M.1    Rahman, G.M.2    Sgobba, V.3    Ehli, C.4
  • 50
    • 55949126429 scopus 로고    scopus 로고
    • Clearance properties of nano-sized particles and molecules as imaging agents: considerations and caveats
    • Longmire, M.; Choyke, P. L.; Kobayashi, H. Clearance properties of nano-sized particles and molecules as imaging agents: considerations and caveats. Nanomedicine 2008, 3, 703-717.
    • (2008) Nanomedicine , vol.3 , pp. 703-717
    • Longmire, M.1    Choyke, P.L.2    Kobayashi, H.3
  • 53
    • 34547738928 scopus 로고    scopus 로고
    • Microarray detection of duplex and triplex DNA binders with DNA-modified gold nanoparticles
    • Lytton-Jean, A. K.; Han, M. S.; Mirkin, C. A. Microarray detection of duplex and triplex DNA binders with DNA-modified gold nanoparticles. Anal. Chem. 2007, 79, 6037-6041.
    • (2007) Anal. Chem. , vol.79 , pp. 6037-6041
    • Lytton-Jean, A.K.1    Han, M.S.2    Mirkin, C.A.3
  • 54
    • 0030768397 scopus 로고    scopus 로고
    • Selective colorimetric detection of polynucleotides based on the distance-dependent optical properties of gold nanoparticles
    • Elghanian, R.; Storhoff, J. J.; Mucic, R. C.; Letsinger, R. L.; Mirkin, C. A. Selective colorimetric detection of polynucleotides based on the distance-dependent optical properties of gold nanoparticles. Science (N.Y.) 1997, 277, 1078-1081.
    • (1997) Science (N.Y.) , vol.277 , pp. 1078-1081
    • Elghanian, R.1    Storhoff, J.J.2    Mucic, R.C.3    Letsinger, R.L.4    Mirkin, C.A.5
  • 55
    • 70349876880 scopus 로고    scopus 로고
    • Synthetically programmable DNA binding domains in aggregates of DNA-functionalized gold nanoparticles
    • Hurst, S. J.; Hill, H. D.; Macfarlane, R. J.; Wu, J.; Dravid, V. P.; Mirkin, C. A. Synthetically programmable DNA binding domains in aggregates of DNA-functionalized gold nanoparticles. Small 2009, 5, 2156-2161.
    • (2009) Small , vol.5 , pp. 2156-2161
    • Hurst, S.J.1    Hill, H.D.2    Macfarlane, R.J.3    Wu, J.4    Dravid, V.P.5    Mirkin, C.A.6
  • 57
    • 0001249911 scopus 로고
    • Dextran-magnetite: a new relaxation reagent and its application to T2 measurements in gel systems
    • Ohgushi, M.; Nagayama, K.; Wada, A. Dextran-magnetite: a new relaxation reagent and its application to T2 measurements in gel systems. J. Magn. Reson. 1978, 29, 599-601.
    • (1978) J. Magn. Reson. , vol.29 , pp. 599-601
    • Ohgushi, M.1    Nagayama, K.2    Wada, A.3
  • 58
    • 0032426610 scopus 로고    scopus 로고
    • Superparamagnetic agents in magnetic resonance imaging.Physicochemical characteristics and clinical applications.A review
    • Bonnemain, B. Superparamagnetic agents in magnetic resonance imaging. Physicochemical characteristics and clinical applications. A review. J. Drug Targeting 1998, 6, 167-174.
    • (1998) J. Drug Targeting , vol.6 , pp. 167-174
    • Bonnemain, B.1
  • 62
    • 0025253906 scopus 로고
    • Ultrasmall superparamagnetic iron oxide: an intravenous contrast agent for assessing lymph nodes with MR imaging
    • Weissleder, R.; Elizondo, G.; Wittenberg, J.; Lee, A. S.; Josephson, L.; Brady, T. J. Ultrasmall superparamagnetic iron oxide: an intravenous contrast agent for assessing lymph nodes with MR imaging. Radiology 1990, 175, 494-498.
    • (1990) Radiology , vol.175 , pp. 494-498
    • Weissleder, R.1    Elizondo, G.2    Wittenberg, J.3    Lee, A.S.4    Josephson, L.5    Brady, T.J.6
  • 64
    • 40549091275 scopus 로고    scopus 로고
    • Magnetic nanoparticles for MR imaging: agents techniques and cardiovascular applications
    • Sosnovik, D. E.; Nahrendorf, M.; Weissleder, R. Magnetic nanoparticles for MR imaging: agents, techniques and cardiovascular applications. Basic Res. Cardiol. 2008, 103, 122- 130.
    • (2008) Basic Res. Cardiol. , vol.103 , pp. 122-130
    • Sosnovik, D.E.1    Nahrendorf, M.2    Weissleder, R.3
  • 65
    • 0030210255 scopus 로고    scopus 로고
    • Superparamagnetic agents: physicochemical characteristics and preclinical imaging evaluation
    • Benderbous, S.; Corot, C.; Jacobs, P.; Bonnemain, B. Superparamagnetic agents: physicochemical characteristics and preclinical imaging evaluation. Acad. Radiol. 1996, 3(Suppl 2), S292-S294.
    • (1996) Acad. Radiol. , vol.3 , Issue.SUPPL 2
    • Benderbous, S.1    Corot, C.2    Jacobs, P.3    Bonnemain, B.4
  • 68
    • 58149267870 scopus 로고    scopus 로고
    • Limitations and relative utility of screening assays to assess engineered nanoparticle toxicity in a human cell line
    • Monteiro-Riviere,N.A.; Inman, A. O.; Zhang, L.W. Limitations and relative utility of screening assays to assess engineered nanoparticle toxicity in a human cell line. Toxicol. Appl. Pharmacol. 2009, 234, 222-235.
    • (2009) Toxicol. Appl. Pharmacol. , vol.234 , pp. 222-235
    • Monteiro-Riviere, N.A.1    Inman, A.O.2    Zhang, L.W.3
  • 69
    • 65749087491 scopus 로고    scopus 로고
    • In vitro assessments of nanomaterial toxicity
    • Jones, C. F.; Grainger, D. W. In vitro assessments of nanomaterial toxicity. Adv. Drug Deliv. Rev. 2009, 61, 438-456.
    • (2009) Adv. Drug Deliv. Rev. , vol.61 , pp. 438-456
    • Jones, C.F.1    Grainger, D.W.2
  • 71
    • 67650481611 scopus 로고    scopus 로고
    • A microfluidic 3D hepatocyte chip for drug toxicity testing
    • Toh, Y. C.; Lim, T. C.; Tai, D.; Xiao, G.; van Noort, D.; Yu, H. A microfluidic 3D hepatocyte chip for drug toxicity testing. Lab on a Chip 2009, 9, 2026-2035.
    • (2009) Lab on a Chip , vol.9 , pp. 2026-2035
    • Toh, Y.C.1    Lim, T.C.2    Tai, D.3    Xiao, G.4    van Noort, D.5    Yu, H.6
  • 72
    • 67649871487 scopus 로고    scopus 로고
    • In vitro toxicity testing of nanoparticles in 3D cell culture
    • Lee, J.; Lilly, G. D.; Doty, R. C.; Podsiadlo, P.; Kotov, N. A. In vitro toxicity testing of nanoparticles in 3D cell culture. Small (Germany) 2009, 5, 1213-1221.
    • (2009) Small (Germany) , vol.5 , pp. 1213-1221
    • Lee, J.1    Lilly, G.D.2    Doty, R.C.3    Podsiadlo, P.4    Kotov, N.A.5
  • 73
    • 45749083389 scopus 로고    scopus 로고
    • High-content screening as a universal tool for fingerprinting of cytotoxicity of nanoparticles
    • Jan, E.; Byrne, S. J.; Cuddihy, M.; Davies, A. M.; Volkov, Y.; Gun'ko, Y. K.; Kotov, N. A. High-content screening as a universal tool for fingerprinting of cytotoxicity of nanoparticles. ACS Nano 2008, 2, 928-938.
    • (2008) ACS Nano , vol.2 , pp. 928-938
    • Jan, E.1    Byrne, S.J.2    Cuddihy, M.3    Davies, A.M.4    Volkov, Y.5    Gun'ko, Y.K.6    Kotov, N.A.7
  • 74
    • 33847607194 scopus 로고    scopus 로고
    • Long-term exposure to CdTe quantum dots causes functional impairments in live cells
    • Cho, S. J.; Maysinger, D.; Jain, M.; Roder, B.; Hackbarth, S.; Winnik, F. M. Long-term exposure to CdTe quantum dots causes functional impairments in live cells. Langmuir 2007, 23, 1974-1980.
    • (2007) Langmuir , vol.23 , pp. 1974-1980
    • Cho, S.J.1    Maysinger, D.2    Jain, M.3    Roder, B.4    Hackbarth, S.5    Winnik, F.M.6
  • 75
    • 33751245917 scopus 로고    scopus 로고
    • Evaluation of quantum dot cytotoxicity based on intracellular uptake13
    • Emmanuel Chang, N. T.; William, W. Y.; Vicki, L. C. R. D. Evaluation of quantum dot cytotoxicity based on intracellular uptake13. Small 2006, 2, 1412-1417.
    • (2006) Small , vol.2 , pp. 1412-1417
    • Emmanuel Chang, N.T.1    William, W.Y.2    Vicki, L.C.R.D.3
  • 76
    • 0842287342 scopus 로고    scopus 로고
    • Probing the cytotoxicity of semiconductor quantum dots
    • Derfus, A. M.; Chan,W. C.W.; Bhatia, S.N. Probing the cytotoxicity of semiconductor quantum dots. Nano Lett. 2004, 4, 11-18.
    • (2004) Nano Lett. , vol.4 , pp. 11-18
    • Derfus, A.M.1    Chan, W.C.W.2    Bhatia, S.N.3
  • 77
    • 34748905976 scopus 로고    scopus 로고
    • Persistent tissue kinetics and redistribution of nanoparticles quantum dot 705 in mice: ICP-MS quantitative assessment
    • Yang, R. S.; Chang, L. W.; Wu, J. P.; Tsai, M. H.; Wang, H. J.; Kuo, Y. C.; Yeh, T. K.; Yang, C. S.; Lin, P. Persistent tissue kinetics and redistribution of nanoparticles, quantum dot 705, in mice: ICP-MS quantitative assessment. Environ. Health Perspect. 2007, 115, 1339-1343.
    • (2007) Environ. Health Perspect. , vol.115 , pp. 1339-1343
    • Yang, R.S.1    Chang, L.W.2    Wu, J.P.3    Tsai, M.H.4    Wang, H.J.5    Kuo, Y.C.6    Yeh, T.K.7    Yang, C.S.8    Lin, P.9
  • 78
  • 79
    • 0030952030 scopus 로고    scopus 로고
    • The integrity of the liver among people environmentally exposed to cadmium at various levels
    • Ikeda, M.;Watanabe, T.; Zhang, Z.W.;Moon, C. S.; Shimbo, S. The integrity of the liver among people environmentally exposed to cadmium at various levels. Int. Arch.Occup. Environ. Health 1997, 69, 379-385.
    • (1997) Int. Arch.Occup. Environ. Health , vol.69 , pp. 379-385
    • Ikeda, M.1    Watanabe, T.2    Zhang, Z.W.3    Moon, C.S.4    Shimbo, S.5
  • 80
    • 33846811207 scopus 로고    scopus 로고
    • A meta-analysis of literature data relating to the relationships between cadmium intake and toxicity indicators in humans
    • Omarova, A.; Phillips, C. J. A meta-analysis of literature data relating to the relationships between cadmium intake and toxicity indicators in humans. Environ. Res. 2007, 103, 432-440.
    • (2007) Environ. Res. , vol.103 , pp. 432-440
    • Omarova, A.1    Phillips, C.J.2
  • 81
    • 70349100115 scopus 로고    scopus 로고
    • Biocompatible near-infrared quantum dots as ultrasensitive probes for long-term in vivo imaging applications
    • Yong, K. T.; Roy, I.; Ding, H.; Bergey, E. J.; Prasad, P. N. Biocompatible near-infrared quantum dots as ultrasensitive probes for long-term in vivo imaging applications. Small (Germany) 2009, 5, 1997-2004.
    • (2009) Small(Germany) , vol.5 , pp. 1997-2004
    • Yong, K.T.1    Roy, I.2    Ding, H.3    Bergey, E.J.4    Prasad, P.N.5
  • 82
    • 27744516368 scopus 로고    scopus 로고
    • Unmodified cadmium telluride quantum dots induce reactive oxygen species formation leading to multiple organelle damage and cell death
    • Lovric, J.; Cho, S. J.; Winnik, F. M.; Maysinger, D. Unmodified cadmium telluride quantum dots induce reactive oxygen species formation leading to multiple organelle damage and cell death. Chem. Biol. 2005, 12, 1227-1234.
    • (2005) Chem. Biol. , vol.12 , pp. 1227-1234
    • Lovric, J.1    Cho, S.J.2    Winnik, F.M.3    Maysinger, D.4
  • 84
    • 33750087538 scopus 로고    scopus 로고
    • Time-dependent photoluminescence blue shift of the quantum dots in living cells: effect of oxidation by singlet oxygen
    • Zhang, Y.; He, J.; Wang, P.-N.; Chen, J.-Y.; Lu, Z.-J.; Lu, D.-R.; Guo, J.; Wang, C.-C.; Yang, W.-L. Time-dependent photoluminescence blue shift of the quantum dots in living cells: effect of oxidation by singlet oxygen. J. Am. Chem. Soc. 2006, 128, 13396-13401.
    • (2006) J. Am. Chem. Soc. , vol.128 , pp. 13396-13401
    • Zhang, Y.1    He, J.2    Wang, P.-N.3    Chen, J.-Y.4    Lu, Z.-J.5    Lu, D.-R.6    Guo, J.7    Wang, C.-C.8    Yang, W.-L.9
  • 85
    • 33751184633 scopus 로고    scopus 로고
    • CdSe quantum dots induce apoptosis in human neuroblastoma cells via mitochondrial-dependent pathways and inhibition of survival signals
    • Chan, W. H.; Shiao, N. H.; Lu, P. Z. CdSe quantum dots induce apoptosis in human neuroblastoma cells via mitochondrial-dependent pathways and inhibition of survival signals. Toxicol. Lett. 2006, 167, 191-200.
    • (2006) Toxicol. Lett. , vol.167 , pp. 191-200
    • Chan, W.H.1    Shiao, N.H.2    Lu, P.Z.3
  • 86
    • 27744548967 scopus 로고    scopus 로고
    • On the generation of free radical species from quantum dots13
    • Binil Itty Ipe, M. L.; Christof, M. N. On the generation of free radical species from quantum dots13. Small 2005, 1, 706-709.
    • (2005) Small , vol.1 , pp. 706-709
    • Binil Itty Ipe, M.L.1    Christof, M.N.2
  • 87
    • 0035850521 scopus 로고    scopus 로고
    • Photochemical instability of CdSe nanocrystals coated by hydrophilic thiols
    • Aldana, J.; Wang, Y. A.; Peng, X. Photochemical instability of CdSe nanocrystals coated by hydrophilic thiols. J. Am. Chem. Soc. 2001, 123, 8844-8850.
    • (2001) J. Am. Chem. Soc. , vol.123 , pp. 8844-8850
    • Aldana, J.1    Wang, Y.A.2    Peng, X.3
  • 88
    • 33749667441 scopus 로고    scopus 로고
    • A systematic examination of surface coatings on the optical and chemical properties of semiconductor quantum dots
    • Smith, A. M.; Duan, H.; Rhyner, M. N.; Ruan, G.; Nie, S. A systematic examination of surface coatings on the optical and chemical properties of semiconductor quantum dots. Phys. Chem. Chem. Phys. 2006, 8, 3895-3903.
    • (2006) Phys. Chem. Chem. Phys. , vol.8 , pp. 3895-3903
    • Smith, A.M.1    Duan, H.2    Rhyner, M.N.3    Ruan, G.4    Nie, S.5
  • 90
    • 34548170316 scopus 로고    scopus 로고
    • Real-time imaging of astrocyte response to quantum dots: in vivo screening model system for biocompatibility of nanoparticles
    • Maysinger, D.; Behrendt, M.; Lalancette-Hebert, M.; Kriz, J. Real-time imaging of astrocyte response to quantum dots: in vivo screening model system for biocompatibility of nanoparticles. Nano Lett. 2007, 7, 2513-2520.
    • (2007) Nano Lett. , vol.7 , pp. 2513-2520
    • Maysinger, D.1    Behrendt, M.2    Lalancette-Hebert, M.3    Kriz, J.4
  • 91
    • 12744273180 scopus 로고    scopus 로고
    • Semiconductor quantum dots and free radical induced DNA nicking
    • Green, M.; Howman, E. Semiconductor quantum dots and free radical induced DNA nicking. Chem. Commun. 2005, 121-123.
    • (2005) Chem. Commun. , pp. 121-123
    • Green, M.1    Howman, E.2
  • 92
    • 23044459574 scopus 로고    scopus 로고
    • Differences in subcellular distribution and toxicity of green and red emitting CdTe quantum dots
    • Lovric, J.; Bazzi, H. S.; Cuie, Y.; Fortin, G. R.; Winnik, F. M.; Maysinger, D. Differences in subcellular distribution and toxicity of green and red emitting CdTe quantum dots. J. Mol. Med. 2005, 83, 377-385.
    • (2005) J. Mol. Med. , vol.83 , pp. 377-385
    • Lovric, J.1    Bazzi, H.S.2    Cuie, Y.3    Fortin, G.R.4    Winnik, F.M.5    Maysinger, D.6
  • 93
    • 33847099979 scopus 로고    scopus 로고
    • Study on DNA damage induced by CdSe quantum dots using nucleic acid molecular "light switches" as probe
    • Liang, J.; He, Z.; Zhang, S.; Huang, S.; Ai, X.; Yang, H.; Han, H. Study on DNA damage induced by CdSe quantum dots using nucleic acid molecular "light switches" as probe. Talanta 2007, 71, 1675-1678.
    • (2007) Talanta , vol.71 , pp. 1675-1678
    • Liang, J.1    He, Z.2    Zhang, S.3    Huang, S.4    Ai, X.5    Yang, H.6    Han, H.7
  • 96
    • 33646397592 scopus 로고    scopus 로고
    • Determining the size and shape dependence of gold nanoparticle uptake into mammalian cells
    • Chithrani, B. D.; Ghazani, A. A.; Chan, W. C. W. Determining the size and shape dependence of gold nanoparticle uptake into mammalian cells. Nano Lett. 2006, 6, 662-668.
    • (2006) Nano Lett. , vol.6 , pp. 662-668
    • Chithrani, B.D.1    Ghazani, A.A.2    Chan, W.C.W.3
  • 97
    • 39649115201 scopus 로고    scopus 로고
    • Particle size-dependent organ distribution of gold nanoparticles after intravenous administration
    • De Jong, W. H.; Hagens, W. I.; Krystek, P.; Burger, M. C.; Sips, A. J.; Geertsma, R. E. Particle size-dependent organ distribution of gold nanoparticles after intravenous administration. Biomaterials 2008, 29, 1912-1919.
    • (2008) Biomaterials , vol.29 , pp. 1912-1919
    • De Jong, W.H.1    Hagens, W.I.2    Krystek, P.3    Burger, M.C.4    Sips, A.J.5    Geertsma, R.E.6
  • 99
    • 25444448098 scopus 로고    scopus 로고
    • Gold nanoparticles are taken up by human cells but do not cause acute cytotoxicity
    • Ellen, E. C.; Judith, M.; Anand, G.; Catherine, J. M.; Michael, D. W. Gold nanoparticles are taken up by human cells but do not cause acute cytotoxicity. Small 2005, 1, 325-327.
    • (2005) Small , vol.1 , pp. 325-327
    • Ellen, E.C.1    Judith, M.2    Anand, G.3    Catherine, J.M.4    Michael, D.W.5
  • 100
    • 69049115300 scopus 로고    scopus 로고
    • Toxicity assessments of multisized gold and silver nanoparticles in zebrafish embryos
    • Ofek, B.-I.; Ralph, M. A.; Valerie, E. F.; Darin, Y. F. Toxicity assessments of multisized gold and silver nanoparticles in zebrafish embryos. Small 2009, 5, 1897-1910.
    • (2009) Small , vol.5 , pp. 1897-1910
    • Ofek, B.-I.1    Ralph, M.A.2    Valerie, E.F.3    Darin, Y.F.4
  • 101
    • 58149164878 scopus 로고    scopus 로고
    • Detoxification of gold nanorods by treatment with polystyrenesulfonate
    • Leonov, A. P.; Zheng, J.; Clogston, J. D.; Stern, S. T.; Patri, A. K.; Wei, A. Detoxification of gold nanorods by treatment with polystyrenesulfonate. ACS Nano 2008, 2, 2481-2488.
    • (2008) ACS Nano , vol.2 , pp. 2481-2488
    • Leonov, A.P.1    Zheng, J.2    Clogston, J.D.3    Stern, S.T.4    Patri, A.K.5    Wei, A.6
  • 103
    • 33646752642 scopus 로고    scopus 로고
    • Cellular uptake and toxicity of Au55 clusters
    • Maria, T. H. K.; Wolfgang, B.; Helmut, E.; Günter, S. Cellular uptake and toxicity of Au55 clusters. Small 2005, 1, 841-844.
    • (2005) Small , vol.1 , pp. 841-844
    • Maria, T.H.K.1    Wolfgang, B.2    Helmut, E.3    Günter, S.4
  • 105
    • 34248208920 scopus 로고    scopus 로고
    • Carbon nanotubes as nanomedicines: from toxicology to pharmacology
    • Lacerda, L.; Bianco, A.; Prato, M.; Kostarelos, K. Carbon nanotubes as nanomedicines: from toxicology to pharmacology. Adv. Drug Deliv. Rev. 2006, 58, 1460-1470.
    • (2006) Adv. Drug Deliv. Rev. , vol.58 , pp. 1460-1470
    • Lacerda, L.1    Bianco, A.2    Prato, M.3    Kostarelos, K.4
  • 106
    • 1542726626 scopus 로고    scopus 로고
    • Pulmonary toxicity of single-wall carbon nanotubes in mice 7 and 90 days after intratracheal instillation
    • Lam, C. W.; James, J. T.; McCluskey, R.; Hunter, R. L. Pulmonary toxicity of single-wall carbon nanotubes in mice 7 and 90 days after intratracheal instillation. Toxicol. Sci. 2004, 77, 126-134.
    • (2004) Toxicol. Sci. , vol.77 , pp. 126-134
    • Lam, C.W.1    James, J.T.2    McCluskey, R.3    Hunter, R.L.4
  • 107
    • 33645744010 scopus 로고    scopus 로고
    • A review of carbon nanotube toxicity and assessment of potential occupational and environmental health risks
    • Lam, C. W.; James, J. T.; McCluskey, R.; Arepalli, S.; Hunter, R. L. A review of carbon nanotube toxicity and assessment of potential occupational and environmental health risks. Crit. Rev. Toxicol. 2006, 36, 189-217.
    • (2006) Crit. Rev. Toxicol. , vol.36 , pp. 189-217
    • Lam, C.W.1    James, J.T.2    McCluskey, R.3    Arepalli, S.4    Hunter, R.L.5
  • 111
    • 50849144653 scopus 로고    scopus 로고
    • Exploring the immunotoxicity of carbon nanotubes
    • Yu, Y.; Zhang, Q.; Mu, Q.; Zhang, B.; Yan, B. Exploring the immunotoxicity of carbon nanotubes. Nanoscale Res. Lett. 2008, 3, 271-277.
    • (2008) Nanoscale Res. Lett. , vol.3 , pp. 271-277
    • Yu, Y.1    Zhang, Q.2    Mu, Q.3    Zhang, B.4    Yan, B.5
  • 113
    • 34848828552 scopus 로고    scopus 로고
    • Reviewing the environmental and human health knowledge base of carbon nanotubes
    • Helland, A.; Wick, P.; Koehler, A.; Schmid, K.; Som, C. Reviewing the environmental and human health knowledge base of carbon nanotubes. Environ. Health Perspect. 2007, 115, 1125-1131.
    • (2007) Environ. Health Perspect. , vol.115 , pp. 1125-1131
    • Helland, A.1    Wick, P.2    Koehler, A.3    Schmid, K.4    Som, C.5
  • 114
    • 3042818668 scopus 로고    scopus 로고
    • Nanotube molecular transporters: internalization of carbon nanotube-protein conjugates into mammalian cells
    • Shi Kam, N. W.; Jessop, T. C.; Wender, P. A.; Dai, H. Nanotube molecular transporters: internalization of carbon nanotube-protein conjugates into mammalian cells. J. Am. Chem. Soc. 2004, 126, 6850-6851.
    • (2004) J. Am. Chem. Soc. , vol.126 , pp. 6850-6851
    • Shi Kam, N.W.1    Jessop, T.C.2    Wender, P.A.3    Dai, H.4
  • 116
    • 49849106093 scopus 로고    scopus 로고
    • Biocompatible carbon nanotubes generated by functionalization with glycodendrimers
    • Wu, P.; Chen, X.; Hu, N.; Tam, U. C.; Blixt, O.; Zettl, A.; Bertozzi, C. R. Biocompatible carbon nanotubes generated by functionalization with glycodendrimers. Angew. Chem. Int. Ed. 2008, 47, 5022-5025.
    • (2008) Angew. Chem. Int. Ed. , vol.47 , pp. 5022-5025
    • Wu, P.1    Chen, X.2    Hu, N.3    Tam, U.C.4    Blixt, O.5    Zettl, A.6    Bertozzi, C.R.7
  • 117
    • 52049100604 scopus 로고    scopus 로고
    • Long-term accumulation and low toxicity of single-walled carbon nanotubes in intravenously exposed mice
    • Yang, S.-T.; Wang, X.; Jia, G.; Gu, Y.; Wang, T.; Nie, H.; Ge, C.; Wang, H.; Liu, Y. Long-term accumulation and low toxicity of single-walled carbon nanotubes in intravenously exposed mice. Toxicol. Lett. 2008, 181, 182-189.
    • (2008) Toxicol. Lett. , vol.181 , pp. 182-189
    • Yang, S.-T.1    Wang, X.2    Jia, G.3    Gu, Y.4    Wang, T.5    Nie, H.6    Ge, C.7    Wang, H.8    Liu, Y.9
  • 119
    • 40349112868 scopus 로고    scopus 로고
    • Circulation and long-term fate of functionalized biocompatible single-walled carbon nanotubes in mice probed by Raman spectroscopy
    • Liu, Z.; Davis, C.; Cai,W.; He, L.; Chen, X.; Dai, H. Circulation and long-term fate of functionalized, biocompatible single-walled carbon nanotubes in mice probed by Raman spectroscopy. Proc. Natl. Acad. Sci. U.S.A. 2008, 105, 1410-1415.
    • (2008) Proc. Natl. Acad. Sci. U.S.A. , vol.105 , pp. 1410-1415
    • Liu, Z.1    Davis, C.2    Cai, W.3    He, L.4    Chen, X.5    Dai, H.6
  • 121
    • 0022628856 scopus 로고
    • Hemochromatosis: how much iron is too much
    • Tavill, A. S.; Bacon, B. R. Hemochromatosis: how much iron is too much? Hepatology 1986, 6, 142-145.
    • (1986) Hepatology , vol.6 , pp. 142-145
    • Tavill, A.S.1    Bacon, B.R.2
  • 123
    • 0027452550 scopus 로고
    • Regulating the fate of mRNA: the control of cellular iron metabolism
    • Klausner, R. D.; Rouault, T. A.; Harford, J. B. Regulating the fate of mRNA: the control of cellular iron metabolism. Cell 1993, 72, 19-28.
    • (1993) Cell , vol.72 , pp. 19-28
    • Klausner, R.D.1    Rouault, T.A.2    Harford, J.B.3
  • 124
    • 0038756705 scopus 로고    scopus 로고
    • Ferucarbotran (Resovist): a new clinically approved RES-specific contrast agent for contrast-enhanced MRI of the liver: properties clinical development and applications
    • Reimer, P.; Balzer, T. Ferucarbotran (Resovist): a new clinically approved RES-specific contrast agent for contrast-enhanced MRI of the liver: properties, clinical development, and applications. Eur. Radiol. 2003, 13, 1266-1276.
    • (2003) Eur. Radiol. , vol.13 , pp. 1266-1276
    • Reimer, P.1    Balzer, T.2
  • 125
    • 0037690119 scopus 로고    scopus 로고
    • Newtypes of silica-fortified magnetic nanoparticles as tools for molecular biology applications
    • Grüttner, C.; Teller, J. Newtypes of silica-fortified magnetic nanoparticles as tools for molecular biology applications. J. Magn. Magn. Mater. 1999, 194, 8-15.
    • (1999) J. Magn. Magn. Mater. , vol.194 , pp. 8-15
    • Grüttner, C.1    Teller, J.2
  • 126
    • 0037767617 scopus 로고    scopus 로고
    • Functionalisation of magnetic nanoparticles for applications in biomedicine
    • Berry, C. C.; Curtis, A. S. G. Functionalisation of magnetic nanoparticles for applications in biomedicine. J. Phys. D: Appl. Phys. 2003, 36, R198-R206.
    • (2003) J. Phys. D: Appl. Phys. , vol.36
    • Berry, C.C.1    Curtis, A.S.G.2
  • 127
    • 42549152143 scopus 로고    scopus 로고
    • Biodistribution clearance and biocompatibility of iron oxide magnetic nanoparticles in rats
    • Jain, T. K.; Reddy, M. K.; Morales, M. A.; Leslie-Pelecky, D. L.; Labhasetwar, V. Biodistribution, clearance, and biocompatibility of iron oxide magnetic nanoparticles in rats. Mol. Pharmacol. 2008, 5, 316-327.
    • (2008) Mol. Pharmacol. , vol.5 , pp. 316-327
    • Jain, T.K.1    Reddy, M.K.2    Morales, M.A.3    Leslie-Pelecky, D.L.4    Labhasetwar, V.5
  • 129
    • 0028020159 scopus 로고
    • imaging with iron oxides: toward consensus and clinical practice
    • Weissleder, R. Liver MR imaging with iron oxides: toward consensus and clinical practice. Radiology 1994, 193, 593-595.
    • (1994) Radiology , vol.193 , pp. 593-595
    • Weissleder, R.1    Liver, M.R.2
  • 130
    • 33645278623 scopus 로고    scopus 로고
    • Preoperative esophageal cancer staging: magnetic resonance imaging of lymph node with ferumoxtran- 10 an ultrasmall superparamagnetic iron oxide
    • Nishimura, H.; Tanigawa, N.;Hiramatsu,M.; Tatsumi,Y.; Matsuki,M.; Narabayashi, I. Preoperative esophageal cancer staging: magnetic resonance imaging of lymph node with ferumoxtran- 10, an ultrasmall superparamagnetic iron oxide. J. Am. Coll. Surg. 2006, 202, 604-611.
    • (2006) J. Am. Coll. Surg. , vol.202 , pp. 604-611
    • Nishimura, H.1    Tanigawa, N.2    Hiramatsu, M.3    Tatsumi, Y.4    Matsuki, M.5    Narabayashi, I.6
  • 132
    • 20644449754 scopus 로고    scopus 로고
    • Nanotoxicology: an emerging discipline evolving from studies of ultrafine particles
    • Oberdorster, G.; Oberdorster, E.; Oberdorster, J. Nanotoxicology: an emerging discipline evolving from studies of ultrafine particles. Environ. Health Perspect. 2005, 113, 823-839.
    • (2005) Environ. Health Perspect. , vol.113 , pp. 823-839
    • Oberdorster, G.1    Oberdorster, E.2    Oberdorster, J.3
  • 133
    • 0034000453 scopus 로고    scopus 로고
    • Tumor vascular permeability and the EPR effect in macromolecular therapeutics: a review
    • Maeda, H.; Wu, J.; Sawa, T.; Matsumura, Y.; Hori, K. Tumor vascular permeability and the EPR effect in macromolecular therapeutics: a review. J. Control. Release 2000, 65, 271- 284.
    • (2000) J. Control. Release , vol.65 , pp. 271-284
    • Maeda, H.1    Wu, J.2    Sawa, T.3    Matsumura, Y.4    Hori, K.5
  • 134
    • 0034993240 scopus 로고    scopus 로고
    • The enhanced permeability and retention (EPR) effect in tumor vasculature: the key role of tumor-selective macromolecular drug targeting
    • Maeda, H. The enhanced permeability and retention (EPR) effect in tumor vasculature: the key role of tumor-selective macromolecular drug targeting. Adv. Enzyme Regul. 2001, 41, 189- 207.
    • (2001) Adv. Enzyme Regul. , vol.41 , pp. 189-207
    • Maeda, H.1
  • 137
    • 33745913004 scopus 로고    scopus 로고
    • Pharmacokinetics of nanoscale quantum dots: in vivo distribution sequestration and clearance in the rat
    • Fischer, H. C.; Pang, K. S.; Chan,W. C.W. Pharmacokinetics of nanoscale quantum dots: in vivo distribution, sequestration, and clearance in the rat. Adv. Funct. Mater. 2006, 16, 1299-1305.
    • (2006) Adv. Funct. Mater. , vol.16 , pp. 1299-1305
    • Fischer, H.C.1    Pang, K.S.2    Chan, W.C.W.3
  • 138
    • 34247491556 scopus 로고    scopus 로고
    • Simultaneous two-color spectral fluorescence lymphangiography with near infrared quantum dots to map two lymphatic flows from the breast and the upper extremity
    • Hama, Y.; Koyama, Y.; Urano, Y.; Choyke, P. L.;Kobayashi, H. Simultaneous two-color spectral fluorescence lymphangiography with near infrared quantum dots to map two lymphatic flows from the breast and the upper extremity. Breast Cancer Res. Treat. 2007, 103, 23-28.
    • (2007) Breast Cancer Res. Treat. , vol.103 , pp. 23-28
    • Hama, Y.1    Koyama, Y.2    Urano, Y.3    Choyke, P.L.4    Kobayashi, H.5
  • 139
  • 140
    • 33644653853 scopus 로고    scopus 로고
    • Size series of small indium arsenide-zinc selenide core-shell nanocrystals and their application to in vivo imaging
    • Zimmer, J. P.; Kim, S.-W.; Ohnishi, S.; Tanaka, E.; Frangioni, J. V.; Bawendi, M. G. Size series of small indium arsenide-zinc selenide core-shell nanocrystals and their application to in vivo imaging. J. Am. Chem. Soc. 2006, 128, 2526-2527.
    • (2006) J. Am. Chem. Soc. , vol.128 , pp. 2526-2527
    • Zimmer, J.P.1    Kim, S.-W.2    Ohnishi, S.3    Tanaka, E.4    Frangioni, J.V.5    Bawendi, M.G.6
  • 142
    • 0030000488 scopus 로고    scopus 로고
    • Development of superparamagnetic nanoparticles for MRI: effect of particle size charge and surface nature on biodistribution
    • Chouly, C.; Pouliquen, D.; Lucet, I.; Jeune, J. J.; Jallet, P. Development of superparamagnetic nanoparticles for MRI: effect of particle size, charge and surface nature on biodistribution. J. Microencapsul. 1996, 13, 245-255.
    • (1996) J. Microencapsul. , vol.13 , pp. 245-255
    • Chouly, C.1    Pouliquen, D.2    Lucet, I.3    Jeune, J.J.4    Jallet, P.5
  • 143
    • 18144377999 scopus 로고    scopus 로고
    • Superparamagnetic nanoparticles for biomedical applications: possibilities and limitations of a new drug delivery system
    • Neuberger, T.; Schöpf, B.; Hofmann, H.; Hofmann, M.; von Rechenberg, B. Superparamagnetic nanoparticles for biomedical applications: possibilities and limitations of a new drug delivery system. J. Magn. Magn. Mater. 2005, 293, 483-496.
    • (2005) J. Magn. Magn. Mater. , vol.293 , pp. 483-496
    • Neuberger, T.1    Schöpf, B.2    Hofmann, H.3    Hofmann, M.4    von Rechenberg, B.5
  • 144
    • 42549152143 scopus 로고    scopus 로고
    • Biodistribution clearance and biocompatibility of iron oxide magnetic nanoparticles in rats
    • Jain, T. K.; Reddy, M. K.; Morales, M. A.; Leslie-Pelecky, D. L.; Labhasetwar, V. Biodistribution, clearance, and biocompatibility of iron oxide magnetic nanoparticles in rats. Mol. Pharmacol. 2008, 5, 316-327.
    • (2008) Mol. Pharmacol. , vol.5 , pp. 316-327
    • Jain, T.K.1    Reddy, M.K.2    Morales, M.A.3    Leslie-Pelecky, D.L.4    Labhasetwar, V.5
  • 145
    • 3042689597 scopus 로고    scopus 로고
    • Hepatic cellular distribution and degradation of iron oxide nanoparticles following single intravenous injection in rats: implications for magnetic resonance imaging
    • Briley-Saebo, K.; Bjornerud, A.; Grant, D.; Ahlstrom, H.; Berg, T.; Kindberg, G. M. Hepatic cellular distribution and degradation of iron oxide nanoparticles following single intravenous injection in rats: implications for magnetic resonance imaging. Cell Tissue Res. 2004, 316, 315-323.
    • (2004) Cell Tissue Res. , vol.316 , pp. 315-323
    • Briley-Saebo, K.1    Bjornerud, A.2    Grant, D.3    Ahlstrom, H.4    Berg, T.5    Kindberg, G.M.6
  • 148
    • 0015605437 scopus 로고
    • The role of the sinus wall in the passage of erythrocytes through the spleen
    • Chen, L.-T.; Weiss, L. The role of the sinus wall in the passage of erythrocytes through the spleen. Blood 1973, 41, 529-537.
    • (1973) Blood , vol.41 , pp. 529-537
    • Chen, L.-T.1    Weiss, L.2
  • 150
    • 38949174620 scopus 로고    scopus 로고
    • A generally adoptable radiotracing method for tracking carbon nanotubes in animals
    • Deng, X.; Yang, S.; Nie, H.; Wang, H.; Liu, Y. A generally adoptable radiotracing method for tracking carbon nanotubes in animals. Nanotechnology 2008, 19, 075101.
    • (2008) Nanotechnology , vol.19 , pp. 075101
    • Deng, X.1    Yang, S.2    Nie, H.3    Wang, H.4    Liu, Y.5
  • 153
    • 0035206137 scopus 로고    scopus 로고
    • Gastrointestinal persorption and tissue distribution of differently sized colloidal gold nanoparticles
    • Hillyer, J. F.; Albrecht, R. M. Gastrointestinal persorption and tissue distribution of differently sized colloidal gold nanoparticles. J. Pharm. Sci. 2001, 90, 1927-1936.
    • (2001) J. Pharm. Sci. , vol.90 , pp. 1927-1936
    • Hillyer, J.F.1    Albrecht, R.M.2
  • 154
    • 33847041884 scopus 로고    scopus 로고
    • Gum arabic as a phytochemical construct for the stabilization of gold nanoparticles: in vivo pharmacokinetics and X-ray-contrast-imaging studies
    • Vijaya, K.; Kavita, K.; Sharanya, B.; Evan, J. B.; Stan W. C.; Genevieve M. F.; David J. R.; Meera, C.; Raghuraman K.; Kattesh V. K. Gum arabic as a phytochemical construct for the stabilization of gold nanoparticles: in vivo pharmacokinetics and X-ray-contrast-imaging studies. Small 2007, 3, 333-341.
    • (2007) Small , vol.3 , pp. 333-341
    • Vijaya, K.1    Kavita, K.2    Sharanya, B.3    Evan, J.B.4    Stan, W.C.5    Genevieve, M.F.6    David, J.R.7    Meera, C.8    Raghuraman, K.9    Kattesh, V.K.10
  • 155
    • 57749207052 scopus 로고    scopus 로고
    • Intravascular delivery of particulate systems: does geometry really matter
    • Decuzzi, P.; Pasqualini, R.; Arap, W.; Ferrari, M. Intravascular delivery of particulate systems: does geometry really matter? Pharm. Res. 2009, 26, 235-243.
    • (2009) Pharm. Res. , vol.26 , pp. 235-243
    • Decuzzi, P.1    Pasqualini, R.2    Arap, W.3    Ferrari, M.4
  • 156
    • 57749178400 scopus 로고    scopus 로고
    • Shape induced inhibition of phagocytosis of polymer particles
    • Champion, J.; Mitragotri, S. Shape induced inhibition of phagocytosis of polymer particles. Pharm. Res. 2009, 26, 244-249.
    • (2009) Pharm. Res. , vol.26 , pp. 244-249
    • Champion, J.1    Mitragotri, S.2
  • 158
    • 63649101776 scopus 로고    scopus 로고
    • Comparison of quantum dot biodistribution with a blood-flow-limited physiologically based pharmacokinetic model
    • Lee, H. A.; Leavens, T. L.; Mason, S. E.;Monteiro-Riviere, N. A.; Riviere, J. E. Comparison of quantum dot biodistribution with a blood-flow-limited physiologically based pharmacokinetic model. Nano Lett. 2009, 9, 794-799.
    • (2009) Nano Lett. , vol.9 , pp. 794-799
    • Lee, H.A.1    Leavens, T.L.2    Mason, S.E.3    Monteiro-Riviere, N.A.4    Riviere, J.E.5
  • 161
    • 0037225979 scopus 로고    scopus 로고
    • Immunofluorescent labeling of cancer marker Her2 and other cellular targets with semiconductor quantum dots
    • Wu, X.; Liu, H.; Liu, J.; Haley, K. N.; Treadway, J. A.; Larson, J. P.; Ge, N.; Peale, F.; Bruchez, M. P. Immunofluorescent labeling of cancer marker Her2 and other cellular targets with semiconductor quantum dots. Nat. Biotechnol. 2003, 21, 41-46.
    • (2003) Nat. Biotechnol. , vol.21 , pp. 41-46
    • Wu, X.1    Liu, H.2    Liu, J.3    Haley, K.N.4    Treadway, J.A.5    Larson, J.P.6    Ge, N.7    Peale, F.8    Bruchez, M.P.9
  • 162
    • 34250157121 scopus 로고    scopus 로고
    • Molecular profiling of single cancer cells and clinical tissue specimens with semiconductor quantum dots
    • Xing, Y.; Smith, A. M.; Agrawal, A.; Ruan, G.; Nie, S. Molecular profiling of single cancer cells and clinical tissue specimens with semiconductor quantum dots. Int. J. Nanomed. 2006, 1, 473-481.
    • (2006) Int. J. Nanomed. , vol.1 , pp. 473-481
    • Xing, Y.1    Smith, A.M.2    Agrawal, A.3    Ruan, G.4    Nie, S.5
  • 165
    • 0032566763 scopus 로고    scopus 로고
    • Quantum dot bioconjugates for ultrasensitive nonisotopic detection
    • Chan, W. C. W.; Nie, S. Quantum dot bioconjugates for ultrasensitive nonisotopic detection. Science (N.Y.) 1998, 281, 2016-2018.
    • (1998) Science (N.Y.) , vol.281 , pp. 2016-2018
    • Chan, W.C.W.1    Nie, S.2
  • 166
    • 34548730278 scopus 로고    scopus 로고
    • Specific integrin labeling in living cells using functionalized nanocrystals
    • Oliver, L.; Mnica L.-G.; Christine, S.; Jorg, A.; Horst, K.; Andreas R. B. Specific integrin labeling in living cells using functionalized nanocrystals. Small 2007, 3, 1560-1565.
    • (2007) Small , vol.3 , pp. 1560-1565
    • Oliver, L.1    Mnica, L.-G.2    Christine, S.3    Jorg, A.4    Horst, K.5    Andreas, R.B.6
  • 167
    • 34547579309 scopus 로고    scopus 로고
    • Characterization of the functional binding properties of antibody conjugated quantum dots
    • Pathak, S.; Davidson, M. C.; Silva, G. A. Characterization of the functional binding properties of antibody conjugated quantum dots. Nano Lett. 2007, 7, 1839-1845.
    • (2007) Nano Lett. , vol.7 , pp. 1839-1845
    • Pathak, S.1    Davidson, M.C.2    Silva, G.A.3
  • 168
    • 34648828733 scopus 로고    scopus 로고
    • Surface engineering of quantum dots for in vivo vascular imaging
    • Jayagopal, A.; Russ, P. K.; Haselton, F. R. Surface engineering of quantum dots for in vivo vascular imaging. Bioconjug. Chem. 2007, 18, 1424-1433.
    • (2007) Bioconjug. Chem. , vol.18 , pp. 1424-1433
    • Jayagopal, A.1    Russ, P.K.2    Haselton, F.R.3
  • 169
    • 0037109752 scopus 로고    scopus 로고
    • Interaction of anionic superparamagnetic nanoparticles with cells: kinetic analyses of membrane adsorption and subsequent internalization
    • Wilhelm, C.; Gazeau, F.; Roger, J.; Pons, J. N.; Bacri, J. C. Interaction of anionic superparamagnetic nanoparticles with cells: kinetic analyses of membrane adsorption and subsequent internalization. Langmuir 2002, 18, 8148-8155.
    • (2002) Langmuir , vol.18 , pp. 8148-8155
    • Wilhelm, C.1    Gazeau, F.2    Roger, J.3    Pons, J.N.4    Bacri, J.C.5
  • 171
    • 34250702267 scopus 로고    scopus 로고
    • Biodistribution of functionalized multiwall carbon nanotubes in mice
    • Jinxue, G.; Xiao, Z.; Qingnuan, L.; Wenxin, L. Biodistribution of functionalized multiwall carbon nanotubes in mice. Nucl. Med. Biol. 2007, 34, 579-583.
    • (2007) Nucl. Med. Biol. , vol.34 , pp. 579-583
    • Jinxue, G.1    Xiao, Z.2    Qingnuan, L.3    Wenxin, L.4
  • 172
    • 33846845060 scopus 로고    scopus 로고
    • In vivo biodistribution and highly efficient tumour targeting of carbon nanotubes in mice
    • Liu, Z.; Cai, W.; He, L.; Nakayama, N.; Chen, K.; Sun, X.; Chen, X.; Dai, H. In vivo biodistribution and highly efficient tumour targeting of carbon nanotubes in mice. Nat. Nano. 2007, 2, 47-52.
    • (2007) Nat. Nano. , vol.2 , pp. 47-52
    • Liu, Z.1    Cai, W.2    He, L.3    Nakayama, N.4    Chen, K.5    Sun, X.6    Chen, X.7    Dai, H.8
  • 176
    • 33747187479 scopus 로고    scopus 로고
    • A macrophage-targeted theranostic nanoparticle for biomedical applications
    • McCarthy, J. R.; Jaffer, F. A.; Weissleder, R. A macrophage-targeted theranostic nanoparticle for biomedical applications. Small (Germany) 2006, 2, 983-987.
    • (2006) Small (Germany) , vol.2 , pp. 983-987
    • McCarthy, J.R.1    Jaffer, F.A.2    Weissleder, R.3
  • 177
    • 67650300243 scopus 로고    scopus 로고
    • Optical and multimodality molecular imaging: insights into atherosclerosis
    • Jaffer, F. A.; Libby, P.; Weissleder, R. Optical and multimodality molecular imaging: insights into atherosclerosis. Arterioscler. Thromb. Vasc. Biol. 2009, 29, 1017-1024.
    • (2009) Arterioscler. Thromb. Vasc. Biol. , vol.29 , pp. 1017-1024
    • Jaffer, F.A.1    Libby, P.2    Weissleder, R.3
  • 178
    • 36248973801 scopus 로고    scopus 로고
    • Quantum dot-aptamer conjugates for synchronous cancer imaging therapy and sensing of drug delivery based on bi-fluorescence resonance energy transfer
    • Bagalkot, V.; Zhang, L.; Levy-Nissenbaum, E.; Jon, S.; Kantoff, P. W.; Langer, R.; Farokhzad, O. C. Quantum dot-aptamer conjugates for synchronous cancer imaging, therapy, and sensing of drug delivery based on bi-fluorescence resonance energy transfer. Nano Lett. 2007, 7, 3065-3070.
    • (2007) Nano Lett. , vol.7 , pp. 3065-3070
    • Bagalkot, V.1    Zhang, L.2    Levy-Nissenbaum, E.3    Jon, S.4    Kantoff, P.W.5    Langer, R.6    Farokhzad, O.C.7
  • 181
    • 69049104359 scopus 로고    scopus 로고
    • Drug/dye-loaded multifunctional iron oxide nanoparticles for combined targeted cancer therapy and dual optical/magnetic resonance imaging
    • Santimukul, S.; Charalambos, K.; Jan, G.; Perez, J. M. Drug/dye-loaded, multifunctional iron oxide nanoparticles for combined targeted cancer therapy and dual optical/magnetic resonance imaging. Small 2009, 5, 1862-1868.
    • (2009) Small , vol.5 , pp. 1862-1868
    • Santimukul, S.1    Charalambos, K.2    Jan, G.3    Perez, J.M.4
  • 182
    • 47349091366 scopus 로고    scopus 로고
    • Proton-sponge coated quantum dots for siRNA delivery and intracellular imaging
    • Yezhelyev, M. V.; Qi, L.; O'Regan, R.M.; Nie, S.; Gao, X. Proton-sponge coated quantum dots for siRNA delivery and intracellular imaging. J. Am. Chem. Soc. 2008, 130, 9006-9012.
    • (2008) J. Am. Chem. Soc. , vol.130 , pp. 9006-9012
    • Yezhelyev, M.V.1    Qi, L.2    O'Regan, R.M.3    Nie, S.4    Gao, X.5


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