메뉴 건너뛰기




Volumn 2, Issue 5, 2008, Pages 928-938

High-content screening as a universal tool for fingerprinting of cytotoxicity of nanoparticles

Author keywords

Biocompatibility; High content assay; High content screening; Nanomedicine; Nanoparticles; Nanotoxicity; Quantum dots

Indexed keywords

CADMIUM; CADMIUM ALLOYS; CADMIUM COMPOUNDS; CALCIUM; CHEMOTHERAPY; CYTOTOXICITY; DIGITAL SIGNAL PROCESSING; DRUG DELIVERY; DRUG DOSAGE; DRUG THERAPY; GOLD; GOLD ALLOYS; IMAGING TECHNIQUES; MATERIALS PROPERTIES; NANOPARTICLES; NANOSTRUCTURED MATERIALS; NANOSTRUCTURES; NUCLEAR PROPULSION; PIGMENTS; QUANTUM ELECTRONICS; SEMICONDUCTING CADMIUM TELLURIDE; SEMICONDUCTOR QUANTUM DOTS; STABILIZERS (AGENTS); TELLURIUM COMPOUNDS;

EID: 45749083389     PISSN: 19360851     EISSN: 1936086X     Source Type: Journal    
DOI: 10.1021/nn7004393     Document Type: Article
Times cited : (166)

References (56)
  • 1
    • 34547273298 scopus 로고    scopus 로고
    • Simulations and Analysis of Self-Assembly of CdTe Nanoparticles into Wires and Sheets
    • Zhang, Z. L.; Tang, Z Y.; Kotov, N. A.; Glotzer, S. C. Simulations and Analysis of Self-Assembly of CdTe Nanoparticles into Wires and Sheets. Nano Lett. 2007, 7, 1670-1675.
    • (2007) Nano Lett , vol.7 , pp. 1670-1675
    • Zhang, Z.L.1    Tang, Z.Y.2    Kotov, N.A.3    Glotzer, S.C.4
  • 4
    • 20644449754 scopus 로고    scopus 로고
    • Oberdorster, G., Oberdorster, E.; Oberdorster, J. Nanotoxicology: An Emerging Discipline Evolving from Studies of Ultrafine Particles. Environ. Health Perspect. 2005, 113, 823-839.
    • Oberdorster, G., Oberdorster, E.; Oberdorster, J. Nanotoxicology: An Emerging Discipline Evolving from Studies of Ultrafine Particles. Environ. Health Perspect. 2005, 113, 823-839.
  • 5
    • 35448948988 scopus 로고    scopus 로고
    • Nanotoxicology - Signs of Stress
    • Stone, V.; Donaldson, K. Nanotoxicology - Signs of Stress. Nat. Nonotechnol. 2006, 1, 23-24.
    • (2006) Nat. Nonotechnol , vol.1 , pp. 23-24
    • Stone, V.1    Donaldson, K.2
  • 7
    • 33747502183 scopus 로고    scopus 로고
    • Quantum Dots in Biological and Biomedical Research: Recent Progress and Present Challenges
    • Klostranec, J. M.; Chan, W. C. W. Quantum Dots in Biological and Biomedical Research: Recent Progress and Present Challenges. Adv. Mater. 2006, 18, 1953-1964.
    • (2006) Adv. Mater , vol.18 , pp. 1953-1964
    • Klostranec, J.M.1    Chan, W.C.W.2
  • 9
    • 0842287342 scopus 로고    scopus 로고
    • Probing the Cytotoxicity of Semiconductor Quantum Dots
    • Derfus, A. M., Chan, W. C. W., Bhatia, S. N. Probing the Cytotoxicity of Semiconductor Quantum Dots. Nano Lett. 2004, 4, 11-18.
    • (2004) Nano Lett , vol.4 , pp. 11-18
    • Derfus, A.M.1    Chan, W.C.W.2    Bhatia, S.N.3
  • 10
    • 9644268826 scopus 로고    scopus 로고
    • Physicochemical Properties and Cellular Toxicity of Nanocrystal Quantum Dots Depend on Their Surface Modification
    • Hoshino, A.; Fujioka, K; Oku, T.; Suga, M., Sasaki, Y. F.; Ohta, T.; Yasuhara, M.; Suzuki, K; Yamamoto, K Physicochemical Properties and Cellular Toxicity of Nanocrystal Quantum Dots Depend on Their Surface Modification. Nano Lett. 2004, 4, 2163-2169.
    • (2004) Nano Lett , vol.4 , pp. 2163-2169
    • Hoshino, A.1    Fujioka, K.2    Oku, T.3    Suga, M.4    Sasaki, Y.F.5    Ohta, T.6    Yasuhara, M.7    Suzuki, K.8    Yamamoto, K.9
  • 11
    • 32044451341 scopus 로고    scopus 로고
    • A Toxicologic Review of Quantum Dots: Toxicity Depends on Physicochemical and Environmental Factors
    • Hardman, R. A Toxicologic Review of Quantum Dots: Toxicity Depends on Physicochemical and Environmental Factors. Environ. Health Perspect. 2006, 774, 165-172.
    • (2006) Environ. Health Perspect , vol.774 , pp. 165-172
    • Hardman, R.1
  • 13
    • 22544448136 scopus 로고    scopus 로고
    • High Content Screening - Emerging Importance of Novel Reagents/Probes and Pathway Analysis
    • Comley, J. High Content Screening - Emerging Importance of Novel Reagents/Probes and Pathway Analysis. Drug Discovery World 2005, 31-53.
    • (2005) Drug Discovery World , pp. 31-53
    • Comley, J.1
  • 14
    • 33646398886 scopus 로고    scopus 로고
    • Cellular Effect of High Doses of Silica-Coated Quantum Dot Profiled with High Throughput Gene Expression Analysis and High Content Cellomics Measurements
    • Zhang, T. T.; Stilwell, J. L; Gerion, D., Ding, L H.; Elboudwarej, O.; Cooke, P. A.; Gray, J. W., Alivisatos, A. P.; Chen, F. F. Cellular Effect of High Doses of Silica-Coated Quantum Dot Profiled with High Throughput Gene Expression Analysis and High Content Cellomics Measurements. Nano Lett. 2006, 6, 800-808.
    • (2006) Nano Lett , vol.6 , pp. 800-808
    • Zhang, T.T.1    Stilwell, J.L.2    Gerion, D.3    Ding, L.H.4    Elboudwarej, O.5    Cooke, P.A.6    Gray, J.W.7    Alivisatos, A.P.8    Chen, F.F.9
  • 16
    • 0348087040 scopus 로고    scopus 로고
    • Long-Term Multiple Color Imaging of Live Cells Using Quantum Dot Bloconjugates
    • Jaiswal, J. K.; Mattoussi, H.; Mauro, J. M., Simon, S. M. Long-Term Multiple Color Imaging of Live Cells Using Quantum Dot Bloconjugates. Nat. Biotechnol. 2003, 21, 47-51.
    • (2003) Nat. Biotechnol , vol.21 , pp. 47-51
    • Jaiswal, J.K.1    Mattoussi, H.2    Mauro, J.M.3    Simon, S.M.4
  • 18
    • 20144379798 scopus 로고    scopus 로고
    • Quantum Dot Bioconjugates for Imaging, Labelling and Sensing
    • Medintz, I. L.; Uyeda, H. T.; Goldman, E. R.; Mattoussi, H. Quantum Dot Bioconjugates for Imaging, Labelling and Sensing. Nat. Mater. 2005, 4, 435-446.
    • (2005) Nat. Mater , vol.4 , pp. 435-446
    • Medintz, I.L.1    Uyeda, H.T.2    Goldman, E.R.3    Mattoussi, H.4
  • 19
    • 0041923880 scopus 로고    scopus 로고
    • Conjugation to Gold Nanoparticles Enhances Polyethylenimine's Transfer of Plasmid DNA into Mammalian Cells
    • Thomas, M.; Klibanov, A. M. Conjugation to Gold Nanoparticles Enhances Polyethylenimine's Transfer of Plasmid DNA into Mammalian Cells. Proc. Natl. Acad. Sci. U.S.A. 2003, 100, 9138-9143.
    • (2003) Proc. Natl. Acad. Sci. U.S.A , vol.100 , pp. 9138-9143
    • Thomas, M.1    Klibanov, A.M.2
  • 21
    • 25144494830 scopus 로고    scopus 로고
    • Chen, J., Wiley, B., Li, Z. Y.; Campbell, D., Saeki, F.; Cang, H.; Au, L.; Lee, J.; Li, X.; Xia, Y. Gold Nanocages: Engineering Their Structure for Biomedical Applications. Adv. Mater. 2005, 17, 2255-2261.
    • Chen, J., Wiley, B., Li, Z. Y.; Campbell, D., Saeki, F.; Cang, H.; Au, L.; Lee, J.; Li, X.; Xia, Y. Gold Nanocages: Engineering Their Structure for Biomedical Applications. Adv. Mater. 2005, 17, 2255-2261.
  • 22
    • 34547579612 scopus 로고    scopus 로고
    • High Sensitivity of In Vivo Detection of Gold Nanorods Using a Laser Optoacoustic Imaging System
    • Eghtedari, M.; Oraevsky, A.; Copland, J. A., Kotov, N. A.; Conjusteau, A.; Motamedi, M. High Sensitivity of In Vivo Detection of Gold Nanorods Using a Laser Optoacoustic Imaging System. Nano Lett. 2007, 7, 1914-1918.
    • (2007) Nano Lett , vol.7 , pp. 1914-1918
    • Eghtedari, M.1    Oraevsky, A.2    Copland, J.A.3    Kotov, N.A.4    Conjusteau, A.5    Motamedi, M.6
  • 23
    • 4544306615 scopus 로고    scopus 로고
    • Bioconjugated Gold Nanoparticles as a Molecular Based Contrast Agent: Implications for Imaging of Deep Tumors Using Optoacoustic Tomography
    • Copland, J. A.; Eghtedari, M.; Popov, V. L.; Kotov, N.; Mamedova, N.; Motamedi, M.; Craevsky, A. A. Bioconjugated Gold Nanoparticles as a Molecular Based Contrast Agent: Implications for Imaging of Deep Tumors Using Optoacoustic Tomography. Mol. Imaging Biol. 2004, 6, 341-349.
    • (2004) Mol. Imaging Biol , vol.6 , pp. 341-349
    • Copland, J.A.1    Eghtedari, M.2    Popov, V.L.3    Kotov, N.4    Mamedova, N.5    Motamedi, M.6    Craevsky, A.A.7
  • 25
    • 33644533247 scopus 로고    scopus 로고
    • Quantum Dot Applications to Neuroscience: New Tools for Probing Neurons and Glia
    • Pathak, S.; Cao, E.; Davidson, M. C.; Jin, S. H.; Silva, G. A. Quantum Dot Applications to Neuroscience: New Tools for Probing Neurons and Glia. J. Neurosci. 2006, 26, 1893-1895.
    • (2006) J. Neurosci , vol.26 , pp. 1893-1895
    • Pathak, S.1    Cao, E.2    Davidson, M.C.3    Jin, S.H.4    Silva, G.A.5
  • 26
    • 18144391953 scopus 로고    scopus 로고
    • Peptide-Conjugated Quantum Dots Activate Neuronal Receptors and Initiate Downstream Signaling of Neurite Growth
    • Vu, T. Q., Maddipati, R.; Blute, T. A.; Nehilla, B. J.; Nusblat, L.; Desai, T. A. Peptide-Conjugated Quantum Dots Activate Neuronal Receptors and Initiate Downstream Signaling of Neurite Growth. Nano Lett. 2005, 5, 603-607.
    • (2005) Nano Lett , vol.5 , pp. 603-607
    • Vu, T.Q.1    Maddipati, R.2    Blute, T.A.3    Nehilla, B.J.4    Nusblat, L.5    Desai, T.A.6
  • 29
    • 23344441028 scopus 로고    scopus 로고
    • In Quantum Dots for Electrical Stimulation of Neural Cells
    • Nanobiophotonics and Biomedical Applications II
    • Winter, J. O.; Gomez, N.; Korgel, B. A., Schmidt, C. E. In Quantum Dots for Electrical Stimulation of Neural Cells. Proc. SPEI-Int. Soc. Opt. Eng. 2005, 5705, 235-246. (Nanobiophotonics and Biomedical Applications II)
    • (2005) Proc. SPEI-Int. Soc. Opt. Eng , vol.5705 , pp. 235-246
    • Winter, J.O.1    Gomez, N.2    Korgel, B.A.3    Schmidt, C.E.4
  • 30
    • 0035900533 scopus 로고    scopus 로고
    • Recognition Molecule Directed Interfacing between Semiconductor Quantum Dots and Nerve Cells
    • Winter, J. O.; Liu, T. Y.; Korgel, B. A.; Schmidt, C. E. Recognition Molecule Directed Interfacing between Semiconductor Quantum Dots and Nerve Cells. Adv. Mater. 2001, 13, 1673-1677.
    • (2001) Adv. Mater , vol.13 , pp. 1673-1677
    • Winter, J.O.1    Liu, T.Y.2    Korgel, B.A.3    Schmidt, C.E.4
  • 31
    • 33847729958 scopus 로고    scopus 로고
    • Nanoscale Engineering of a Cellular Interface with Semiconductor Nanoparticle Films for Photoelectric Stimulation of Neurons
    • Pappas, T. C.; Wickramanyake, W. M. S.; Jan, E.; Motamedi, M.; Brodwick, M.; Kotov, N. A. Nanoscale Engineering of a Cellular Interface with Semiconductor Nanoparticle Films for Photoelectric Stimulation of Neurons. Nano Lett. 2007, 7, 513-519.
    • (2007) Nano Lett , vol.7 , pp. 513-519
    • Pappas, T.C.1    Wickramanyake, W.M.S.2    Jan, E.3    Motamedi, M.4    Brodwick, M.5    Kotov, N.A.6
  • 33
    • 33751184633 scopus 로고    scopus 로고
    • CdSe Quantum Dots Induce Apoptosis in Human Neuroblastoma Cells via Mitochondrial-Dependent Pathways and Inhibition of Survival Signals
    • Chan, W. H.; Shiao, N. H.; Lu, P. Z. CdSe Quantum Dots Induce Apoptosis in Human Neuroblastoma Cells via Mitochondrial-Dependent Pathways and Inhibition of Survival Signals. Toxicol. Lett. 2006, 167, 191-200.
    • (2006) Toxicol. Lett , vol.167 , pp. 191-200
    • Chan, W.H.1    Shiao, N.H.2    Lu, P.Z.3
  • 34
    • 0036639317 scopus 로고    scopus 로고
    • Applications of Hormesis in Toxicology, Risk Assessment and Chemotherapeutics
    • Calabrese, E. J.; Baldwin, L. A. Applications of Hormesis in Toxicology, Risk Assessment and Chemotherapeutics. Trends Pharmacol. Sci. 2002, 23, 331-337.
    • (2002) Trends Pharmacol. Sci , vol.23 , pp. 331-337
    • Calabrese, E.J.1    Baldwin, L.A.2
  • 36
    • 7444229195 scopus 로고    scopus 로고
    • Applications of Cytotoxicity Assays and Pre-lethal Mechanistic Assays for Assessment of Human Pepatotoxicity Potential
    • Xu, J. J.; Diaz, D.; O'Brien, P. J. Applications of Cytotoxicity Assays and Pre-lethal Mechanistic Assays for Assessment of Human Pepatotoxicity Potential. Chem.-Biol. Interact. 2004, 150, 115-128.
    • (2004) Chem.-Biol. Interact , vol.150 , pp. 115-128
    • Xu, J.J.1    Diaz, D.2    O'Brien, P.J.3
  • 37
    • 0032977356 scopus 로고    scopus 로고
    • Monitoring Simultaneous Subcellular Events In Vitro by Means of Coherent Multiprobe Fluorescence
    • Plymale, D. R.; Haskins, J. R.; Iglesia, F. A. d. I. Monitoring Simultaneous Subcellular Events In Vitro by Means of Coherent Multiprobe Fluorescence. Nat. Med. (N.Y.) 1999, 5, 351-355.
    • (1999) Nat. Med. (N.Y.) , vol.5 , pp. 351-355
    • Plymale, D.R.1    Haskins, J.R.2    Iglesia, F.A.D.I.3
  • 39
    • 4544264062 scopus 로고    scopus 로고
    • Mitochondrial Membrane Potential and Aging
    • Nicholls, D. G. Mitochondrial Membrane Potential and Aging. Aging Cell 2004, 3, 35-40.
    • (2004) Aging Cell , vol.3 , pp. 35-40
    • Nicholls, D.G.1
  • 41
    • 15944417512 scopus 로고    scopus 로고
    • Techniques: High-Throughput Measurement of Intracellular Ca2+-Back to Basics
    • Monteith, G. R.; Bird, G. S. J. Techniques: High-Throughput Measurement of Intracellular Ca2+-Back to Basics. Trends Pharmacol. Sci. 2005, 26, 218-223.
    • (2005) Trends Pharmacol. Sci , vol.26 , pp. 218-223
    • Monteith, G.R.1    Bird, G.S.J.2
  • 42
    • 34249092704 scopus 로고    scopus 로고
    • Calcium and Neurodegeneration
    • Mattson, M. P. Calcium and Neurodegeneration. Aging Cell 2007, 6, 337-350.
    • (2007) Aging Cell , vol.6 , pp. 337-350
    • Mattson, M.P.1
  • 43
    • 0036181718 scopus 로고    scopus 로고
    • Distinct Effects of Different Calcium-Mobilizing Agents on Cell Death in NG108-15 Neuroblastoma X Glioma Cells
    • Chin, T.-Y.; Hwang, H.-M.; Chueh, S.-H. Distinct Effects of Different Calcium-Mobilizing Agents on Cell Death in NG108-15 Neuroblastoma X Glioma Cells. Mol. Pharmacol. 2002, 61, 486-494.
    • (2002) Mol. Pharmacol , vol.61 , pp. 486-494
    • Chin, T.-Y.1    Hwang, H.-M.2    Chueh, S.-H.3
  • 44
    • 3242666765 scopus 로고
    • Ca2+-Dependent Mechanisms of Cytotoxicity and Programmed Cell Death
    • Orrenius, S.; McCabe, M. J.; Nicotera, P. Ca2+-Dependent Mechanisms of Cytotoxicity and Programmed Cell Death. Toxicol. Lett. 1992, 64-65, 357-364.
    • (1992) Toxicol. Lett , vol.64-65 , pp. 357-364
    • Orrenius, S.1    McCabe, M.J.2    Nicotera, P.3
  • 45
    • 0016836315 scopus 로고
    • Gene Expression in Mouse Neuroblastoma Cells: Properties of the Genome
    • Zornetzer, M. S.; Stein, G. S. Gene Expression in Mouse Neuroblastoma Cells: Properties of the Genome. Proc. Natl. Acad Sci. U.S.A. 1975, 72, 3119-3123.
    • (1975) Proc. Natl. Acad Sci. U.S.A , vol.72 , pp. 3119-3123
    • Zornetzer, M.S.1    Stein, G.S.2
  • 46
    • 0032741629 scopus 로고    scopus 로고
    • Immortalized Dopamine Neurons: A Model to Study Neurotoxicity and Neuroprotection
    • Clarkson, E. D.; Edwards-Prasad, J.; Freed, C. R.; Prasad, K. N. Immortalized Dopamine Neurons: A Model to Study Neurotoxicity and Neuroprotection. Proc. Soc. Exp. Biol. Med. 1999, 222, 157-163.
    • (1999) Proc. Soc. Exp. Biol. Med , vol.222 , pp. 157-163
    • Clarkson, E.D.1    Edwards-Prasad, J.2    Freed, C.R.3    Prasad, K.N.4
  • 51
    • 4744371613 scopus 로고    scopus 로고
    • Inverted Colloidal Crystals as Three-Dimensional Cell Scaffolds
    • Kotov, N. A. Inverted Colloidal Crystals as Three-Dimensional Cell Scaffolds. Langmuir 2004, 20, 7887-7892.
    • (2004) Langmuir , vol.20 , pp. 7887-7892
    • Kotov, N.A.1
  • 52
    • 33748431207 scopus 로고    scopus 로고
    • Inverted Colloidal Crystals as Three-Dimensional Microenvironments for Cellular Co-Cultures
    • Lee, J.; Lee, J. Inverted Colloidal Crystals as Three-Dimensional Microenvironments for Cellular Co-Cultures. J. Mater. Chem. 2006, 16, 3558-3564.
    • (2006) J. Mater. Chem , vol.16 , pp. 3558-3564
    • Lee, J.1    Lee, J.2
  • 53
    • 20844451602 scopus 로고    scopus 로고
    • Dynamic Reassembly of Peptide RADA16 Nanofiber Scaffold
    • Yokoi, H.; Kinoshita, T.; Zhang, S. Dynamic Reassembly of Peptide RADA16 Nanofiber Scaffold. Proc. Natl. Acad. Sci. U.S.A. 2005, 102, 8414-8419.
    • (2005) Proc. Natl. Acad. Sci. U.S.A , vol.102 , pp. 8414-8419
    • Yokoi, H.1    Kinoshita, T.2    Zhang, S.3
  • 54
    • 14844286184 scopus 로고    scopus 로고
    • Bioactive Hydrogels with an Ordered Cellular Structure Combine Interconnected Macroporosity and Robust Mechanical Properties
    • Stachowiak, A. N.; Bershteyn, A.; Tzatzalos, E.; Irvine, D. J. Bioactive Hydrogels with an Ordered Cellular Structure Combine Interconnected Macroporosity and Robust Mechanical Properties. Adv. Mater. 2005, 17, 399-403.
    • (2005) Adv. Mater , vol.17 , pp. 399-403
    • Stachowiak, A.N.1    Bershteyn, A.2    Tzatzalos, E.3    Irvine, D.J.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.