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Volumn 2, Issue 1, 2002, Pages 11-18

Scaling down imaging: Molecular mapping of cancer in mice

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; CARBON 11; DYSPROSIUM; FLUORESCENT DYE; FLUORINE 18; GADOLINIUM; INDIUM 111; IODINE; IRON OXIDE; LUCIFERIN; OXYGEN 15; TECHNETIUM 99M; TUMOR PROTEIN;

EID: 0036359767     PISSN: 1474175X     EISSN: None     Source Type: Journal    
DOI: 10.1038/nrc701     Document Type: Review
Times cited : (625)

References (69)
  • 1
    • 0034626769 scopus 로고    scopus 로고
    • The age of cancer
    • DePinho, R. A. The age of cancer Nature 408, 248-254 (2000).
    • (2000) Nature , vol.408 , pp. 248-254
    • DePinho, R.A.1
  • 2
    • 0033028043 scopus 로고    scopus 로고
    • The role of p53 in tumour suppression: Lessons from mouse models
    • Attardi, L. D. & Jacks, T. The role of p53 in tumour suppression: lessons from mouse models. Cell. Mol. Life Sci. 55, 48-63 (1999).
    • (1999) Cell. Mol. Life Sci. , vol.55 , pp. 48-63
    • Attardi, L.D.1    Jacks, T.2
  • 3
    • 0034632717 scopus 로고    scopus 로고
    • Telomere dysfunction promotes non-reciprocal translocations and epithelial cancers in mice
    • Artandi, S. et al. Telomere dysfunction promotes non-reciprocal translocations and epithelial cancers in mice. Nature 406, 641-645 (2000).
    • (2000) Nature , vol.406 , pp. 641-645
    • Artandi, S.1
  • 4
    • 0034006104 scopus 로고    scopus 로고
    • Applications of magnetic resonance in model systems: Tumor biology and physiology
    • Gillies, R. et al. Applications of magnetic resonance in model systems: tumor biology and physiology. Neoplasia 2, 139-151 (2000).
    • (2000) Neoplasia , vol.2 , pp. 139-151
    • Gillies, R.1
  • 5
    • 0032709714 scopus 로고    scopus 로고
    • In vivo assessment of vascular endothelial growth factor-induced angiogenesis
    • Lewin, M. et al. In vivo assessment of vascular endothelial growth factor-induced angiogenesis. Int. J. Cancer 83, 798-802 (1999).
    • (1999) Int. J. Cancer , vol.83 , pp. 798-802
    • Lewin, M.1
  • 6
    • 0032695525 scopus 로고    scopus 로고
    • MR imaging of tumor microcirculation: Promise for the new millennium
    • Taylor, J. S. et al. MR imaging of tumor microcirculation: promise for the new millennium. J. Magn. Reson. Imaging 10, 903-907 (1999).
    • (1999) J. Magn. Reson. Imaging , vol.10 , pp. 903-907
    • Taylor, J.S.1
  • 7
    • 0032145497 scopus 로고    scopus 로고
    • Mapping of tumor vascular and interstitial volume fractions non-invasively in vivo
    • Weissleder, R., Cheng, H., Marecos, E., Kwong, K. & Bogdanov, A. Mapping of tumor vascular and interstitial volume fractions non-invasively in vivo. Eur. J. Cancer 34, 1448-1454 (1998).
    • (1998) Eur. J. Cancer , vol.34 , pp. 1448-1454
    • Weissleder, R.1    Cheng, H.2    Marecos, E.3    Kwong, K.4    Bogdanov, A.5
  • 8
    • 0031895851 scopus 로고    scopus 로고
    • Dynamic functional imaging of relative cerebral blood volume during rat forepaw stimulation
    • Mandeville, J. B. et al. Dynamic functional imaging of relative cerebral blood volume during rat forepaw stimulation. Magn. Reson. Med. 39, 615-624 (1998).
    • (1998) Magn. Reson. Med. , vol.39 , pp. 615-624
    • Mandeville, J.B.1
  • 9
    • 0035042683 scopus 로고    scopus 로고
    • In vivo BOLD contrast MRI mapping of subcutaneous vascular function and maturation: Validation by intravital microscopy
    • Neeman, M., Dafni, H., Bukhan, O., Braun, R. D. & Dewhirst, M. W. In vivo BOLD contrast MRI mapping of subcutaneous vascular function and maturation: validation by intravital microscopy. Magn. Reson. Med. 45, 887-898 (2001).
    • (2001) Magn. Reson. Med. , vol.45 , pp. 887-898
    • Neeman, M.1    Dafni, H.2    Bukhan, O.3    Braun, R.D.4    Dewhirst, M.W.5
  • 10
    • 0031421953 scopus 로고    scopus 로고
    • Assessing tumor angiogenesis using macromolecular MR imaging contrast media
    • Brasch, R. et al. Assessing tumor angiogenesis using macromolecular MR imaging contrast media. J. Magn. Reson. Imaging 7, 68-74 (1997).
    • (1997) J. Magn. Reson. Imaging , vol.7 , pp. 68-74
    • Brasch, R.1
  • 11
    • 0031756068 scopus 로고    scopus 로고
    • NMR imaging of changes in vascular morphology due to tumor angiogenesis
    • Dennie, J. et al. NMR imaging of changes in vascular morphology due to tumor angiogenesis Magn. Reson. Med. 40, 793-799 (1998).
    • (1998) Magn. Reson. Med. , vol.40 , pp. 793-799
    • Dennie, J.1
  • 12
    • 0033756128 scopus 로고    scopus 로고
    • Magnetic resonance spectroscopic studies of the prostate
    • discussion 153
    • Koutcher, J. A., Zakian, K. & Hricak, H. Magnetic resonance spectroscopic studies of the prostate. Mol. Urol. 4, 143-152; discussion 153 (2000).
    • (2000) Mol. Urol. , vol.4 , pp. 143-152
    • Koutcher, J.A.1    Zakian, K.2    Hricak, H.3
  • 13
    • 0031862889 scopus 로고    scopus 로고
    • Detection of tumor angiogenesis in vivo by αVβ3-targeted magnetic resonance imaging
    • Sipkins, D. A. et al. Detection of tumor angiogenesis in vivo by αVβ3-targeted magnetic resonance imaging, Nature Med. 4, 623-626 (1998).
    • (1998) Nature Med. , vol.4 , pp. 623-626
    • Sipkins, D.A.1
  • 14
    • 0002808591 scopus 로고    scopus 로고
    • Oligomerization of paramagnetic substrates result in signal amplification and can be used for MR imaging of molecular targets
    • Bogdanov, A., Matuszewski, L., Bremer, C., Petrovsky, A. & Weissleder, R, Oligomerization of paramagnetic substrates result in signal amplification and can be used for MR imaging of molecular targets. Mol. Imaging 1, 1-9 (2001).
    • (2001) Mol. Imaging , vol.1 , pp. 1-9
    • Bogdanov, A.1    Matuszewski, L.2    Bremer, C.3    Petrovsky, A.4    Weissleder, R.5
  • 15
    • 0034062857 scopus 로고    scopus 로고
    • In vivo magnetic resonance imaging of transgene expression
    • Weissleder, R. et al. In vivo magnetic resonance imaging of transgene expression. Nature Med. 6, 351-355 (2000).
    • (2000) Nature Med. , vol.6 , pp. 351-355
    • Weissleder, R.1
  • 16
    • 0035801531 scopus 로고    scopus 로고
    • Magnetic nanosensors for the detection of oligonucleotide sequences
    • Josephson, L., Perez, M. & Weissleder, R. Magnetic nanosensors for the detection of oligonucleotide sequences. Angew. Chem. (Int Ed. Engl.) 40, 3204-3206 (2001). Describes the use of magnetic nanoparticles as sensors to read out DNA hybridization and, potentially, interactions between large and small molecules. Similar nanoparticles are also used for imaging of other molecular targets by high-resolution MRI.
    • (2001) Angew. Chem. (Int Ed. Engl.) , vol.40 , pp. 3204-3206
    • Josephson, L.1    Perez, M.2    Weissleder, R.3
  • 17
    • 0034006169 scopus 로고    scopus 로고
    • Tat peptide-derevatized magnetic nanoparticles allow in vivo tracking and recovery of progenitor cells
    • Lewin, M. et al. Tat peptide-derevatized magnetic nanoparticles allow in vivo tracking and recovery of progenitor cells. Nature Biotechnol. 18, 410-414 (2000). Describes a versatile magnetic label that can be used to image a variety of cell types in vivo. Labelled cells were isolated after intravenous injection using a magnetic separation column.
    • (2000) Nature Biotechnol. , vol.18 , pp. 410-414
    • Lewin, M.1
  • 18
    • 0034111937 scopus 로고    scopus 로고
    • High resolution computed tomography and MRI for monitoring lung tumor growth in mice undergoing radioimmunotherapy: Correlation with histology
    • Kennel, S. J. et al. High resolution computed tomography and MRI for monitoring lung tumor growth in mice undergoing radioimmunotherapy: correlation with histology. Med. Phys. 27, 1101-1107 (2000).
    • (2000) Med. Phys. , vol.27 , pp. 1101-1107
    • Kennel, S.J.1
  • 19
    • 0035870103 scopus 로고    scopus 로고
    • Three-dimensional microimaging (MRmicrol and microCT), finite element modeling, and rapid prototyping provide unique insights into bone architecture in osteoporosis
    • Borah, B. et al. Three-dimensional microimaging (MRmicrol and microCT), finite element modeling, and rapid prototyping provide unique insights into bone architecture in osteoporosis. Anat. Rec. 265, 101-101 (2001).
    • (2001) Anat. Rec. , vol.265 , pp. 101-101
    • Borah, B.1
  • 20
    • 0034088968 scopus 로고    scopus 로고
    • High resolution X-ray computed tomography: An emerging tool for small animal cancer research
    • Paulus, M. J., Gleason, S. S., Kennel, S. J., Hunsicker, P. R. & Johnson, D. K. High resolution X-ray computed tomography: an emerging tool for small animal cancer research. Neoplasia 2, 62-70 (2000).
    • (2000) Neoplasia , vol.2 , pp. 62-70
    • Paulus, M.J.1    Gleason, S.S.2    Kennel, S.J.3    Hunsicker, P.R.4    Johnson, D.K.5
  • 21
    • 0035288499 scopus 로고    scopus 로고
    • A review of high-resolution X-ray computed tomography and other imaging modalities for small animal research
    • Paulus, M. J., Gleason, S. S., Easterly, M. E. & Foltz, C. J. A review of high-resolution X-ray computed tomography and other imaging modalities for small animal research. Lab. Anim. (NY) 30, 36-45 (2001).
    • (2001) Lab. Anim. (NY) , vol.30 , pp. 36-45
    • Paulus, M.J.1    Gleason, S.S.2    Easterly, M.E.3    Foltz, C.J.4
  • 22
    • 0029776386 scopus 로고    scopus 로고
    • Ultrasound backscatter microscope analysis of mouse melanoma progression
    • Turnbull, D. et al. Ultrasound backscatter microscope analysis of mouse melanoma progression. Ultrasound Med. Biol. 22, 845-853 (1996).
    • (1996) Ultrasound Med. Biol. , vol.22 , pp. 845-853
    • Turnbull, D.1
  • 23
    • 0034923763 scopus 로고    scopus 로고
    • Sonographic evaluation of orthopic bladder tumors in mice treated with, TNP-470, an angiogenesis inhibitor
    • Rooks, V., Beecken, W., Iordanescu, I. & Taylor, J. A. Sonographic evaluation of orthopic bladder tumors in mice treated with, TNP-470, an angiogenesis inhibitor. Acad. Radiol. 8, 121-127 (2001).
    • (2001) Acad. Radiol. , vol.8 , pp. 121-127
    • Rooks, V.1    Beecken, W.2    Iordanescu, I.3    Taylor, J.A.4
  • 24
    • 0034282515 scopus 로고    scopus 로고
    • Effects of PTK787/ZK 222584, a specific inhibitor of vascular endothelial growth factor receptor tyrosine kinases, on primary tumor, metastasis, vessel density, and blood flow in a murine renal cell carcinoma model
    • Drevs, J. et al. Effects of PTK787/ZK 222584, a specific inhibitor of vascular endothelial growth factor receptor tyrosine kinases, on primary tumor, metastasis, vessel density, and blood flow in a murine renal cell carcinoma model. Cancer Res. 60, 4819-4824 (2000).
    • (2000) Cancer Res. , vol.60 , pp. 4819-4824
    • Drevs, J.1
  • 25
    • 0032127782 scopus 로고    scopus 로고
    • Ultrasonic mapping of the microvasculature: Signal alignment
    • Zagar, B., Fornaris, R. & Ferrara, K. Ultrasonic mapping of the microvasculature: signal alignment. Ultrasound Med. Biol. 24, 809-824 (1998).
    • (1998) Ultrasound Med. Biol. , vol.24 , pp. 809-824
    • Zagar, B.1    Fornaris, R.2    Ferrara, K.3
  • 26
    • 0033770962 scopus 로고    scopus 로고
    • Evaluation of tumor angiogenesis with US: Imaging, Doppler, and contrast agents
    • Ferrara, K. W. et al. Evaluation of tumor angiogenesis with US: imaging, Doppler, and contrast agents. Acad. Radiol. 7, 824-839 (2000).
    • (2000) Acad. Radiol. , vol.7 , pp. 824-839
    • Ferrara, K.W.1
  • 28
    • 0032123510 scopus 로고    scopus 로고
    • Alteration of limb and brain patterning in early mouse embryos by ultrasound-guided injection of Shh-expressing cells
    • Liu, A., Joyner, A. L. & Turnbull, D. H. Alteration of limb and brain patterning in early mouse embryos by ultrasound-guided injection of Shh-expressing cells. Mech. Dev. 75, 107-115 (1998).
    • (1998) Mech. Dev. , vol.75 , pp. 107-115
    • Liu, A.1    Joyner, A.L.2    Turnbull, D.H.3
  • 29
    • 0035266374 scopus 로고    scopus 로고
    • Noninvasive imaging of α(v)β3 integrin expression using 18F-labeled RGD-containing glycopeptide and positron emission tomography
    • Haubner, R. et al. Noninvasive imaging of α(v)β3 integrin expression using 18F-labeled RGD-containing glycopeptide and positron emission tomography. Cancer Res. 61, 1781-1785 (2001).
    • (2001) Cancer Res. , vol.61 , pp. 1781-1785
    • Haubner, R.1
  • 30
    • 0031790264 scopus 로고    scopus 로고
    • 8F]FLT and positron emission tomography
    • 8F]FLT and positron emission tomography. Nature Med. 4, 1334-1336 (1998).
    • (1998) Nature Med. , vol.4 , pp. 1334-1336
    • Shields, A.F.1
  • 31
    • 0034072198 scopus 로고    scopus 로고
    • Positron emission tomography (PET) in diagnostic oncology: Is it a necessary tool today?
    • Price, R. Positron emission tomography (PET) in diagnostic oncology: is it a necessary tool today ? Eur. J. Cancer 36, 691-693 (2000).
    • (2000) Eur. J. Cancer , vol.36 , pp. 691-693
    • Price, R.1
  • 32
    • 6544233317 scopus 로고    scopus 로고
    • Repetitive, non-invasive imaging of the dopamine D2 receptor as a reporter gene in living animals
    • MacLaren, D. C. et al. Repetitive, non-invasive imaging of the dopamine D2 receptor as a reporter gene in living animals. Gene Ther. 6, 785-791 (1999).
    • (1999) Gene Ther. , vol.6 , pp. 785-791
    • MacLaren, D.C.1
  • 33
    • 0028304314 scopus 로고
    • Imaging, biodistribution and therapeutic potential of halogenated tamoxifen analogues
    • Yarg, D. et al. Imaging, biodistribution and therapeutic potential of halogenated tamoxifen analogues. Life Sci. 55, 53-67 (1994).
    • (1994) Life Sci. , vol.55 , pp. 53-67
    • Yarg, D.1
  • 34
    • 9544242826 scopus 로고    scopus 로고
    • Noninvasive imaging of herpes virus thymidine kinase gene transfer and expression: A pothential method for monitoring clinical gene therapy
    • Tjuvajev, J. G. et al. Noninvasive imaging of herpes virus thymidine kinase gene transfer and expression: a pothential method for monitoring clinical gene therapy. Cancer Res. 56, 4087-4095 (1996).
    • (1996) Cancer Res. , vol.56 , pp. 4087-4095
    • Tjuvajev, J.G.1
  • 35
    • 13044260220 scopus 로고    scopus 로고
    • Imaging adenoviral-directed reporter gene expression in living animals with positron emission tomography
    • Gambhir, S. S. et al. Imaging adenoviral-directed reporter gene expression in living animals with positron emission tomography. Proc. Natl Acad. Sci. USA 96, 2333-2338 (1999).
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 2333-2338
    • Gambhir, S.S.1
  • 36
    • 0034917741 scopus 로고    scopus 로고
    • Beyond the genome: Molecular imaging in vivo with PET and SPECT
    • Luker, G. & Piwnica-Worms, D. Beyond the genome: molecular imaging in vivo with PET and SPECT. Acad. Radiol. 8, 4-14 (2001).
    • (2001) Acad. Radiol. , vol.8 , pp. 4-14
    • Luker, G.1    Piwnica-Worms, D.2
  • 37
    • 0034048929 scopus 로고    scopus 로고
    • Imaging transgene expression with radionuclide imaging technologies
    • Gambhir, S. et al. imaging transgene expression with radionuclide imaging technologies. Neoplasia 2, 118-138 (2000).
    • (2000) Neoplasia , vol.2 , pp. 118-138
    • Gambhir, S.1
  • 38
    • 0032797916 scopus 로고    scopus 로고
    • Assays for non-invasive imaging of reporter gene expression
    • Gambhir, S., Bardo, J., Herschman, H. & Phelps, M. Assays for non-invasive imaging of reporter gene expression. Nucl Med. Biol. 26, 481-490 (1999).
    • (1999) Nucl Med. Biol. , vol.26 , pp. 481-490
    • Gambhir, S.1    Bardo, J.2    Herschman, H.3    Phelps, M.4
  • 39
    • 0344564162 scopus 로고    scopus 로고
    • Imaging adenoviral-mediated herpes virus thymidine kinase gene transfer and expression in vivo
    • Tjuvajev, J. G. et al. Imaging adenoviral-mediated herpes virus thymidine kinase gene transfer and expression in vivo. Cancer Res. 59, 5186-5193 (1999).
    • (1999) Cancer Res. , vol.59 , pp. 5186-5193
    • Tjuvajev, J.G.1
  • 40
    • 0035979208 scopus 로고    scopus 로고
    • Imaging transcriptional regulation of p53-dependent genes with positron emission tomography in vivo
    • Doubrovin, M. et al. Imaging transcriptional regulation of p53-dependent genes with positron emission tomography in vivo. Proc. Natl Acad. Sci. USA 98, 9300-9305 (2001).
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , pp. 9300-9305
    • Doubrovin, M.1
  • 41
    • 0034234255 scopus 로고    scopus 로고
    • Adenovirus-mediated transfer of the thyroid sodium/iodide symporter gene into tumors for a targeted radiotherapy
    • Boland, A. et al. Adenovirus-mediated transfer of the thyroid sodium/iodide symporter gene into tumors for a targeted radiotherapy, Cancer Res. 60, 3484-3492 (2000).
    • (2000) Cancer Res. , vol.60 , pp. 3484-3492
    • Boland, A.1
  • 42
    • 0035108750 scopus 로고    scopus 로고
    • Single-photon emission computed tomography in the year 2001: Instrumentation and quality control
    • Groch, M. W. & Erwin W. D. Single-photon emission computed tomography in the year 2001: instrumentation and quality control. J. Nucl. Med. Technol. 29, 12-18 (2001).
    • (2001) J. Nucl. Med. Technol. , vol.29 , pp. 12-18
    • Groch, M.W.1    Erwin, W.D.2
  • 43
    • 13144305073 scopus 로고    scopus 로고
    • In vivo detection and imaging of phosphatidylserine expression during programmed cell death
    • Blankenberg, F. G. et al. In vivo detection and imaging of phosphatidylserine expression during programmed cell death. Proc. Natl Acad. Sci. USA 95, 6349-6354 (1998).
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 6349-6354
    • Blankenberg, F.G.1
  • 44
    • 0030873487 scopus 로고    scopus 로고
    • Localization of iodine-125-mIP-Des-Met14-bombesin (7-13)NH2 in ovarian carcinoma induced to express the gastrin releasing peptide receptor by adenoviral vector-mediated gene transfer
    • Rogers, B. et al. Localization of iodine-125-mIP-Des-Met14-bombesin (7-13)NH2 in ovarian carcinoma induced to express the gastrin releasing peptide receptor by adenoviral vector-mediated gene transfer J. Nucl. Med. 38, 1221-1229 (1997).
    • (1997) J. Nucl. Med. , vol.38 , pp. 1221-1229
    • Rogers, B.1
  • 46
    • 0028786434 scopus 로고
    • Technetium-99m labeling of DNA oligonucleotides
    • Hnatowich, D. J, et al. Technetium-99m labeling of DNA oligonucleotides. J. Nucl. Med. 36, 2306-2314 (1995).
    • (1995) J. Nucl. Med. , vol.36 , pp. 2306-2314
    • Hnatowich, D.J.1
  • 47
    • 0032709859 scopus 로고    scopus 로고
    • Radioiodinated antibody targeting of the HER-2/neu oncoprotein: Effects of labeling method on cellular processing and tissue distribution
    • Zalutsky, M. R. et al. Radioiodinated antibody targeting of the HER-2/ neu oncoprotein: effects of labeling method on cellular processing and tissue distribution. Nucl. Med. Biol. 26, 781-790 (1999).
    • (1999) Nucl. Med. Biol. , vol.26 , pp. 781-790
    • Zalutsky, M.R.1
  • 48
    • 0035057893 scopus 로고    scopus 로고
    • Simultaneous evaluation of dual gene transfer to adherent cells by gamma-ray imaging
    • Zinn, K. R., Chaudhudri, T. R., Buchsbaum, D. J., Mountz, J. M. & Rogers, B. E. Simultaneous evaluation of dual gene transfer to adherent cells by gamma-ray imaging. Nucl. Med. Biol. 28, 135-144 (2001).
    • (2001) Nucl. Med. Biol. , vol.28 , pp. 135-144
    • Zinn, K.R.1    Chaudhudri, T.R.2    Buchsbaum, D.J.3    Mountz, J.M.4    Rogers, B.E.5
  • 49
    • 0029071281 scopus 로고
    • Tumor receptor imaging: Proceedings of the National Cancer Institute workshop, review of current work, and prospective for further investigations
    • Katzenellenbogen, J. A. et al. Tumor receptor imaging: proceedings of the National Cancer Institute workshop, review of current work, and prospective for further investigations. Clin. Cancer Res. 1, 921-932 (1995).
    • (1995) Clin. Cancer Res. , vol.1 , pp. 921-932
    • Katzenellenbogen, J.A.1
  • 50
    • 0030808619 scopus 로고    scopus 로고
    • Technetium-99m-labeled receptor-specific small-molecule radiopharmaceuticals: Recent developments and encouraging results
    • Hom, R. K. & Katzenellenbogen, J. A. Technetium-99m-labeled receptor-specific small-molecule radiopharmaceuticals: recent developments and encouraging results. Nucl. Med. Biol. 24, 485-498 (1997).
    • (1997) Nucl. Med. Biol. , vol.24 , pp. 485-498
    • Hom, R.K.1    Katzenellenbogen, J.A.2
  • 51
    • 85031437205 scopus 로고    scopus 로고
    • Systemic distribution and tumor localization of adoptively transferred lymphocytes in mice: Comparison with physiologically based pharmacokinetic model
    • in the press
    • Melder, R. et al. Systemic distribution and tumor localization of adoptively transferred lymphocytes in mice: comparison with physiologically based pharmacokinetic model Neoplasia (in the press).
    • Neoplasia
    • Melder, R.1
  • 52
    • 0033759311 scopus 로고    scopus 로고
    • Quantitation of HSV mass distribution in a rodent brain tumor model
    • Schellingerhout, D., Rainov, N.,Breakefield, X. & Weissleder, R. Quantitation of HSV mass distribution in a rodent brain tumor model. Gene Ther. 7,1648-1655 (2000).
    • (2000) Gene Ther. , vol.7 , pp. 1648-1655
    • Schellingerhout, D.1    Rainov, N.2    Breakefield, X.3    Weissleder, R.4
  • 53
    • 0032697682 scopus 로고    scopus 로고
    • Near-infrared optical imaging of protease activity for tumor detection
    • Mahmood, U., Tung, C. H., Bogdanov, A., Jr & Weissleder, R. Near-infrared optical imaging of protease activity for tumor detection. Radiology 213, 866-870 (1999).
    • (1999) Radiology , vol.213 , pp. 866-870
    • Mahmood, U.1    Tung, C.H.2    Bogdanov A., Jr.3    Weissleder, R.4
  • 54
    • 0035878874 scopus 로고    scopus 로고
    • Detection of peritoneal micrometastases of gastric carcinoma with green fluorescent protein and carcinoembryonic antigen promoter
    • Kaneko, K. et al. Detection of peritoneal micrometastases of gastric carcinoma with green fluorescent protein and carcinoembryonic antigen promoter. Cancer Res. 61, 5570-5574 (2001).
    • (2001) Cancer Res. , vol.61 , pp. 5570-5574
    • Kaneko, K.1
  • 55
    • 0035066562 scopus 로고    scopus 로고
    • Receptor targeted optical imaging of tumors with near infrared flurorescent ligands
    • Becker, A. et al. Receptor targeted optical imaging of tumors with near infrared flurorescent ligands. Nature Biotechnol. 19, 327-331 (2001).
    • (2001) Nature Biotechnol. , vol.19 , pp. 327-331
    • Becker, A.1
  • 56
    • 0028225314 scopus 로고
    • Antibody-indocyanin conjugates for immunophotodetection of human squamous cell carcinoma in nude mice
    • Folli, S. et al. Antibody-indocyanin conjugates for immunophotodetection of human squamous cell carcinoma in nude mice. Cancer Res. 54, 2643-2649 (1994).
    • (1994) Cancer Res. , vol.54 , pp. 2643-2649
    • Folli, S.1
  • 57
    • 0032951071 scopus 로고    scopus 로고
    • In vivo imaging of tumors with protease-activated near-infrared fluorescent probes
    • Weissleder, R., Tung, C. H. Mahmood, U. & Bogdanov, A. Jr. in vivo imaging of tumors with protease-activated near-infrared fluorescent probes. Nature Biotechnol. 17, 375-378 (1999).
    • (1999) Nature Biotechnol. , vol.17 , pp. 375-378
    • Weissleder, R.1    Tung, C.H.2    Mahmood, U.3    Bogdanov A., Jr.4
  • 58
    • 0034954524 scopus 로고    scopus 로고
    • In vivo molecular target assessment of matrix metalloproteinase inhibition
    • Bremer, C., Tung, C. H. & Weissleder, R. In vivo molecular target assessment of matrix metalloproteinase inhibition. Nature Med. 7, 743-748 (2001). Describes novel fluorescent sensors that are specific for proteinases, and explains how they can be used to image therapeutic proteanase inhibition in vivo.
    • (2001) Nature Med. , vol.7 , pp. 743-748
    • Bremer, C.1    Tung, C.H.2    Weissleder, R.3
  • 59
    • 0034283034 scopus 로고    scopus 로고
    • In vivo imaging of proteolytic enzyme activity using a novel molecular reporter
    • Tung, C. H., Mahmood, U., Bredow, S. & Weissleder, R. In vivo imaging of proteolytic enzyme activity using a novel molecular reporter. Cancer Res. 60, 4953-4958 (2000).
    • (2000) Cancer Res. , vol.60 , pp. 4953-4958
    • Tung, C.H.1    Mahmood, U.2    Bredow, S.3    Weissleder, R.4
  • 60
    • 0032837028 scopus 로고    scopus 로고
    • Broad antitumor and antiangiogenic activities of AG 3340, a potent and selective MMP inhibitor undergoing advanced oncology clinical trials
    • Shalinsky, D. R. et al. Broad antitumor and antiangiogenic activities of AG3340, a potent and selective MMP inhibitor undergoing advanced oncology clinical trials. Ann. NY Acad. Sci. 878, 236-270 (1999).
    • (1999) Ann. NY Acad. Sci. , vol.878 , pp. 236-270
    • Shalinsky, D.R.1
  • 61
    • 0036161155 scopus 로고    scopus 로고
    • Detection of dysplastic intestinal adenomas using enzyme sensing molecular beacons
    • in the press
    • Marten, K. et al. Detection of dysplastic intestinal adenomas using enzyme sensing molecular beacons. Gastroenterology (in the press).
    • Gastroenterology
    • Marten, K.1
  • 62
    • 0001273549 scopus 로고    scopus 로고
    • Experimental three-dimensional fluorescence reconstruction of diffuse media by use of a normalized Born approximation
    • Ntziachristos, V. & Weissleder, R. Experimental three-dimensional fluorescence reconstruction of diffuse media by use of a normalized Born approximation. Optics Lett. 26, 893-895 (2001).
    • (2001) Optics Lett. , vol.26 , pp. 893-895
    • Ntziachristos, V.1    Weissleder, R.2
  • 63
    • 0142206378 scopus 로고    scopus 로고
    • Can near-infrared fluorescence propagate through human organs for non-invasive clinical examinations?
    • in the press
    • Ntziachristos, V., Ripoll, J. & Weissleder, R. Can near-infrared fluorescence propagate through human organs for non-invasive clinical examinations? Optics Lett. (in the press).
    • Optics Lett.
    • Ntziachristos, V.1    Ripoll, J.2    Weissleder, R.3
  • 64
    • 0034646351 scopus 로고    scopus 로고
    • Concurrent MRI diffuse optical tomography of breast after indocyanine green enhancement
    • Ntziachristos, V., Yodh, A. G. Schnall, M. & Chance, B. Concurrent MRI and diffuse optical tomography of breast after indocyanine green enhancement. Proc. Natl Acad. Sci. USA 97, 2767-2772 (2000).
    • (2000) Proc. Natl. Acad. Sci. USA , vol.97 , pp. 2767-2772
    • Ntziachristos, V.1    Yodh, A.G.2    Schnall, M.3    Chance, B.4
  • 65
    • 0029619210 scopus 로고
    • Photonic detection of bacterial pathogens in living hosts
    • Contag, C. H. et al. Photonic detection of bacterial pathogens in living hosts. Mol. Microbiol. 18, 593-603 (1995).
    • (1995) Mol. Microbiol. , vol.18 , pp. 593-603
    • Contag, C.H.1
  • 66
    • 0034005650 scopus 로고    scopus 로고
    • Use of reporter genes for optical measurements of neoplastic disease in vivo
    • Contag, C. H., Jenkins, D., Contag, P. R. & Negrin R. S. Use of reporter genes for optical measurements of neoplastic disease in vivo, Neoplasia 2, 41-52 (2000).
    • (2000) Neoplasia , vol.2 , pp. 41-52
    • Contag, C.H.1    Jenkins, D.2    Contag, P.R.3    Negrin, R.S.4
  • 67
    • 0142206377 scopus 로고    scopus 로고
    • High throughput MR imaging for evaluating targeted magnetic nanoparticle probes
    • in the press
    • Hoegeman, D., Ntziachristos, V., Josephson, L. & Weissleder, R. High throughput MR imaging for evaluating targeted magnetic nanoparticle probes. Bioconj. Chem. (in the press).
    • Bioconj. Chem.
    • Hoegeman, D.1    Ntziachristos, V.2    Josephson, L.3    Weissleder, R.4
  • 68
    • 0342445413 scopus 로고    scopus 로고
    • In vivo visualization of gene expression using magnetic resonance imaging
    • Louie, A, Y. et al. In vivo visualization of gene expression using magnetic resonance imaging. Nature Biotechnol. 18, 321-325 (2000).
    • (2000) Nature Biotechnol. , vol.18 , pp. 321-325
    • Louie, A.Y.1
  • 69
    • 0030843681 scopus 로고    scopus 로고
    • A 'smart' magnetic resonance imaging agent that reports on specific enzymatic activity
    • Moats, R. A., Fraser, S. E. & Meade, T. J. A 'smart' magnetic resonance imaging agent that reports on specific enzymatic activity. Angew. Chem. Int. Ed. Engl. 36, 726-731 (1997).
    • (1997) Angew. Chem. Int. Ed. Engl. , vol.36 , pp. 726-731
    • Moats, R.A.1    Fraser, S.E.2    Meade, T.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.