CdSe quantum dots induce apoptosis in human neuroblastoma cells via mitochondrial-dependent pathways and inhibition of survival signals

Toxicology Letters

Volumn 167, Issue 3, 2006, Pages 191-200

  Chan, Wen Hsiung ^a   Shiao, Nion Heng ^a   Lu, Pin Zhen ^a  

^a CHUNG YUAN CHRISTIAN UNIVERSITY   (Taiwan)

Author keywords

Apoptosis; ERK; JNK; Quantum dot; ROS

Indexed keywords

CADMIUM; CASPASE 3; CASPASE 9; CYTOCHROME C; MITOGEN ACTIVATED PROTEIN KINASE; RAF PROTEIN; RAS PROTEIN; SELENIUM; ZINC SULFIDE;

APOPTOSIS; ARTICLE; BRAIN MITOCHONDRION; CANCER CELL CULTURE; CELL MEMBRANE POTENTIAL; CELL SURVIVAL; COATED PARTICLE; CONTROLLED STUDY; CYTOTOXICITY; ENZYME ACTIVATION; ENZYME INHIBITION; ENZYME RELEASE; HUMAN; HUMAN CELL; MITOCHONDRIAL MEMBRANE; MITOCHONDRIAL TOXICITY; NEUROBLASTOMA CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; QUANTUM DOT;

APOPTOSIS; CADMIUM COMPOUNDS; CASPASE 3; CASPASE 9; CELL LINE, TUMOR; CELL SURVIVAL; HSP90 HEAT-SHOCK PROTEINS; HUMANS; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MITOCHONDRIA; NEUROBLASTOMA; QUANTUM DOTS; REACTIVE OXYGEN SPECIES; SELENIUM COMPOUNDS; SIGNAL TRANSDUCTION;

EID: 33751184633     PISSN: 03784274     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.toxlet.2006.09.007     Document Type: Article

References (27)

1. Anderson P. Kinase cascades regulating entry into apoptosis. Microbiol. Mol. Biol. Rev. 61 (1997) 33-46
2. Blagosklonny M.V. Hsp-90-associated oncoproteins: multiple targets of geldanamycin and its analogs. Leukemia 16 (2002) 455-462
3. Caraglia M., Abbruzzese A., Leardi A., Pepe S., Budillon A., Baldassare G., Selleri C., Lorenzo S.D., Fabbrocini A., Giuberti G., Vitale G., Lupoli G., Bianco A.R., and Tagliaferri P. Interferon-alpha induces apoptosis in human KB cells through a stress-dependent mitogen activated protein kinase pathway that is antagonized by epidermal growth factor. Cell Death Differ. 6 (1999) 773-780
4. Caraglia M., D'Alessandro A.M., Marra M., Giuberti G., Vitale G., Viscomi C., Colao A., Prete S.D., Tagliaferri P., Tassone P., Budillon A., Venuta S., and Abbruzzese A. The farnesyl transferase inhibitor R115777 (Zarnestra) synergistically enhances growth inhibition and apoptosis induced on epidermoid cancer cells by zoledronic acid (zometa) and pamidronate. Oncogene 23 (2004) 6900-6913
5. Caraglia M., Marra M., Pelaia G., Maselli R., Caputi M., Marsico S.A., and Abbruzzese A. Alpha-interferon and its effects on signal transduction pathways. J. Cell. Physiol. 202 (2005) 323-335
6. Caraglia M., Tagliaferri P., Marra M., Giuberti G., Budillon A., Gennaro E.D., Pepe S., Vitale G., Improta S., Tassone P., Venuta S., Bianco A.R., and Abbruzzese A. EGF activates an inducible survival response via the RAS-> Erk-1/2 pathway to counteract interferon-alpha-mediated apoptosis in epidermoid cancer cells. Cell Death Differ. 10 (2003) 218-229
7. Chan W.H. Effect of resveratrol on high glucose-induced stress in human leukemia K562 cells. J. Cell. Biochem. 94 (2005) 1267-1279
8. Chan W.H., Wu C.C., and Yu J.S. Curcumin inhibits UV irradiation-induced oxidative stress and apoptotic biochemical changes in human epidermoid carcinoma A431 cells. J. Cell. Biochem. 90 (2003) 327-338
9. Chan W.H., and Wu H.J. Anti-apoptotic effects of curcumin on photosensitized human epidermal carcinoma A431 cells. J. Cell. Biochem. 92 (2004) 200-212
10. Derfus A.M., Chan W.C.W., and Bhatia S.N. Probing the cytotoxicity of semiconductor quantum dots. Nano Lett. 4 (2004) 11-18
11. Erhardt P., and Cooper G.M. Activation of the CPP32 apoptotic protease by distinct signaling pathways with differential sensitivity to Bcl-xL. J. Biol. Chem. 271 (1996) 17601-17604
12. French P.W., Penny R., Laurence J.A., and McKenzie D.R. Mobile phones, heat shock proteins and cancer. Differentiation 67 (2001) 93-97
13. Goldman E.R., Balighian E.D., Mattoussi H., Kuno M.K., Mauro J.M., Tran P.T., and Anderson G.P. Avidin: a natural bridge for quantum dot-antibody conjugates. J. Am. Chem. Soc. 124 (2002) 6378-6382
14. Green D.R., and Reed J.C. Mitochondria and apoptosis. Science 281 (1998) 1309-1312
15. Hoshino A., Hanaki K., Suzuki K., and Yamamoto K. Applications of T-lymphoma labeled with fluorescent quantum dots to cell tracing markers in mouse body. Biochem. Biophys. Res. Commun. 314 (2004) 46-53
16. Hsieh Y.J., Wu C.C., Chang C.J., and Yu J.S. Subcellular localization of Photofrin determines the death phenotype of human epidermoid carcinoma A431 cells triggered by photodynamic therapy: when plasma membranes are the main targets. J. Cell. Physiol. 194 (2003) 363-375
17. Hsuuw Y.D., Chang C.K., Chan W.H., and Yu J.S. Curcumin prevents methylglyoxal-induced oxidative stress and apoptosis in mouse embryonic stem cells and blastocysts. J. Cell. Physiol. 205 (2005) 379-386
18. Kroemer G., Zamzami N., and Susin S.A. Mitochondrial control of apoptosis. Immunol. Today 18 (1997) 44-51
19. Leszczynski D., Joenvaara S., Reivinen J., and Kuokka R. Non-thermal activation of the hsp27/p38MAPK stress pathway by mobile phone radiation in human endothelial cells: molecular mechanism for cancer- and blood-brain barrier-related effects. Differentiation 70 (2002) 120-129
20. Martins L.M., Kottke T., Mesner P.W., Basi G.S., Sinha S., Frigon Jr. N., Tatar E., Tung J.S., Bryant K., Takahashi A., Svingen P.A., Madden B.J., McCormick D.J., Earnshaw W.C., and Kaufmann S.H. Activation of multiple interleukin-1beta converting enzyme homologues in cytosol and nuclei of HL-60 cells during etoposide-induced apoptosis. J. Biol. Chem. 272 (1997) 7421-7430
21. Mayer M.P., and Bukau B. Molecular chaperones: the busy life of Hsp90. Curr. Biol. 9 (1999) R322-R325
22. Murray C.B., Kagan C.R., and Bawendi M.G. Synthesis and characterization of monodisperse nanocrystals and close packed nanocrystal assemblies. Annu. Rev. Mater. Sci. 30 (2000) 545-610
23. Oh S.H., and Lim S.C. A rapid and transient ROS generation by cadmium triggers apoptosis via caspase-dependent pathway in HepG2 cells and this is inhibited through N-acetylcysteine-mediated catalase upregulation. Toxicol. Appl. Pharmacol. 212 (2006) 212-223
24. Pratt W.B., and Toft D.O. Regulation of signaling protein function and trafficking by the hsp90/hsp70-based chaperone machinery. Exp. Biol. Med. (Maywood) 228 (2003) 111-133
25. Seimiya H., Mashima T., Toho M., and Tsuruo T. c-Jun NH2-terminal kinase-mediated activation of interleukin-1beta converting enzyme/CED-3-like protease during anticancer drug-induced apoptosis. J. Biol. Chem. 272 (1997) 4631-4636
26. Tsujimoto Y., and Shimizu S. Bcl-2 family: life-or-death switch. FEBS Lett. 466 (2000) 6-10
27. Zhu N., and Wang Z. An assay for DNA fragmentation in apoptosis without phenol/chloroform extraction and ethanol precipitation. Anal. Biochem. 246 (1997) 155-158