MicroPET-based biodistribution of quantum dots in living mice

Journal of Nuclear Medicine

Volumn 48, Issue 9, 2007, Pages 1511-1518

  Schipper, Meike L ^a   Cheng, Zhen ^a   Lee, Sheen Woo ^a   Bentolila, Laurent A ^b   Iyer, Gopal ^b   Rao, Jianghong ^a   Chen, Xiaoyuan ^a   Wu, Anna M ^b   Weiss, Shimon ^b   Gambhir, Sanjiv S ^a  

^a STANFORD UNIVERSITY   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Biodistribution; Molecular imaging; Nanoparticle; PET; Quantum dot

Indexed keywords

1,4,7,10 TETRAAZACYCLODODECANE 1,4,7,10 TETRAACETIC ACID; CADMIUM DERIVATIVE; CADMIUM SELENIDE; COPPER 64; MACROGOL; NANOPARTICLE; QUANTUM DOT; SELENIDE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; BONE; DRUG CLEARANCE; LIVER; MOLECULAR IMAGING; MOUSE; NONHUMAN; PARTICLE SIZE; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; RADIOISOTOPE DISTRIBUTION; SPLEEN; TISSUE DISTRIBUTION; URINARY EXCRETION;

ANIMALS; BONE AND BONES; CADMIUM COMPOUNDS; COPPER RADIOISOTOPES; LIVER; MICE; MICE, NUDE; POLYETHYLENE GLYCOLS; POSITRON-EMISSION TOMOGRAPHY; QUANTUM DOTS; SELENIUM COMPOUNDS; SPLEEN; TISSUE DISTRIBUTION; ZINC COMPOUNDS;

EID: 34548593380     PISSN: 01615505     EISSN: None     Source Type: Journal    
DOI: 10.2967/jnumed.107.040071     Document Type: Article

References (24)

1. Michalet X, Pinaud FF, Bentolila LA, et al. Quantum dots for live cells, in vivo imaging, and diagnostics. Science. 2005;307:538-544.
2. Gao X, Yang L, Petros JA, Marshall FF, Simons JW, Nie S. In vivo molecular and cellular imaging with quantum dots. Curr Opin Biotechnol. 2005;16:63-72.
3. Gao X, Cui Y, Levenson RM, Chung LW, Nie S. In vivo cancer targeting and imaging with semiconductor quantum dots. Nat Biotechnol. 2004;22:969-976.
4. Chu TC, Shieh F, Lavery LA, et al. Labeling tumor cells with fluorescent nanocrystal-aptamer bioconjugates. Biosens Bioelectron. 2006;21:1859-1866.
5. Akerman ME, Chan WC, Laakkonen P, Bhatia SN, Ruoslahti E. Nanocrystal targeting in vivo. Proc Natl Acad Sci USA. 2002;99:12617-12621.
6. Cai W, Shin DW, Chen K, et al. Peptide-labeled near-infrared quantum dots for imaging tumor vasculature in living subjects. Nano Lett. 2006;6:669-676.
7. Bharali DJ, Lucey DW, Jayakumar H, Pudavar HE, Prasad PN. Folate-receptor-mediated delivery of InP quantum dots for bioimaging using confocal and two-photon microscopy. J Am Chem Soc. 2005;127:11364-11371.
8. Stroh M, Zimmer JP, Duda DG, et al. Quantum dots spectrally distinguish multiple species within the tumor milieu in vivo. Nat Med. 2005;11:678-682.
9. Allen C, Dos Santos N, Gallagher R, et al. Controlling the physical behavior and biological performance of liposome formulations through use of surface grafted poly(ethylene glycol). Biosci Rep. 2002;22:225-250.
10. Owens DE III, Peppas NA. Opsonization, biodistribution, and pharmacokinetics of polymeric nanoparticles. Int J Pharm. 2006;307:93-102.
11. Parungo CP, Ohnishi S, Kim SW, et al. Intraoperative identification of esophageal sentinel lymph nodes with near-infrared fluorescence imaging. J Thorac Cardiovasc Surg. 2005;129:844-850.
12. Soltesz EG, Kim S, Kim SW, et al. Sentinel lymph node mapping of the gastrointestinal tract by using invisible light. Ann Surg Oncol. 2006;13:386-396.
13. Zimmer JP, Kim SW, Ohnishi S, Tanaka E, Frangioni JV, Bawendi MG. Size series of small indium arsenide-zinc selenide core-shell nanocrystals and their application to in vivo imaging. J Am Chem Soc. 2006;128:2526-2527.
14. Thorne RG, Nicholson C. In vivo diffusion analysis with quantum dots and dextrans predicts the width of brain extracellular space. Proc Natl Acad Sci USA. 2006;103:5567-5572.
15. Ballou B, Lagerholm BC, Ernst LA, Bruchez MP, Waggoner AS. Noninvasive imaging of quantum dots in mice. Bioconjug Chem. 2004;15:79-86.
16. Comsa DC, Farrell TJ, Patterson MS. Quantification of bioluminescence images of point source objects using diffusion theory models. Phys Med Biol. 2006;51:3733-3746.
17. So MK, Xu C, Loening AM, Gambhir SS, Rao J. Self-illuminating quantum dot conjugates for in vivo imaging. Nat Biotechnol. 2006;24:339-343.
18. 18F-fluorothymidine microPET studies in tumor xenografts in mice. J Nucl Med. 2005;46:1851-1857.
19. Knoess C, Siegel S, Smith A, et al. Performance evaluation of the microPET R4 PET scanner for rodents. Eur J Nucl Med Mol Imaging. 2003;30:737-747.
20. Loening AM, Gambhir SS. AMIDE: a free software tool for multimodality medical image analysis. Mol Imaging. 2003;2:131-137.
21. Moghimi SM, Szebeni J. Stealth liposomes and long circulating nanoparticles: critical issues in pharmacokinetics, opsonization and protein-binding properties. Prog Lipid Res. 2003;42:463-478.
22. Laverman P, Boerman OC, Oyen WJG, Corstens FHM, Storm G. In vivo applications of PEG liposomes: unexpected observations. Crit Rev Ther Drug Carrier Syst. 2001;18:551-566.
23. Laverman P, Brouwers AH, Dams ET, et al. Preclinical and clinical evidence for disappearance of long-circulating characteristics of polyethylene glycol liposomes at low lipid dose. J Pharmacol Exp Ther. 2000;293:996-1001.
24. Laverman P, Carstens MG, Boerman OC, et al. Factors affecting the accelerated blood clearance of polyethylene glycol-liposomes upon repeated injection. J Pharmacol Exp Ther. 2001;298:607-612.