Nonfunctionalized nanocrystals can exploit a cell's active transport machinery delivering them to specific nuclear and cytoplasmic compartments

Nano Letters

Volumn 7, Issue 11, 2007, Pages 3452-3461

  Nabiev, Igor ^a   Mitchell, Siobhan ^b   Davies, Anthony ^b   Williams, Yvonne ^b   Kelleher, Dermot ^b   Moore, Richard ^b   Gun'ko, Yurii K ^b   Byrne, Stephen ^b   Rakovich, Yury P ^b   Donegan, John F ^b   Sukhanova, Alyona ^a   Conroy, Jennifer ^b   Cottell, David ^c   Gaponik, Nikolai ^d   Rogach, Andrey ^e   Volkov, Yuri ^b  

^a UNIVERSITÉ DE REIMS CHAMPAGNE ARDENNE   (France)

^b TRINITY COLLEGE DUBLIN   (Ireland)

^c UNIVERSITY COLLEGE DUBLIN   (Ireland)

^d DRESDEN UNIVERSITY OF TECHNOLOGY   (Germany)

^e UNIVERSITY OF MUNICH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

MACROPHAGES; SEMICONDUCTOR QUANTUM DOTS; TRANSMISSION ELECTRON MICROSCOPY;

CELLULAR TRANSPORT; CYTOPLASMIC COMPARTMENTS; CYTOPLASMIC TRANSPORT; FLUORESCENT IMAGING;

NANOCRYSTALS;

NANOPARTICLE; THAPSIGARGIN;

ACTIVE TRANSPORT; ARTICLE; BIOLOGICAL MODEL; CELL NUCLEUS; CHEMISTRY; CYTOPLASM; ENDOTHELIUM; EPITHELIUM CELL; HUMAN; MACROPHAGE; METABOLISM; METHODOLOGY; MONOCYTE; NANOTECHNOLOGY; PHAGOCYTOSIS; TRANSMISSION ELECTRON MICROSCOPY; VASCULAR ENDOTHELIUM;

BIOLOGICAL TRANSPORT, ACTIVE; CELL NUCLEUS; CYTOPLASM; ENDOTHELIUM; ENDOTHELIUM, VASCULAR; EPITHELIAL CELLS; HUMANS; MACROPHAGES; MICROSCOPY, ELECTRON, TRANSMISSION; MODELS, BIOLOGICAL; MONOCYTES; NANOPARTICLES; NANOTECHNOLOGY; PHAGOCYTOSIS; THAPSIGARGIN;

EID: 36749055209     PISSN: 15306984     EISSN: None     Source Type: Journal    
DOI: 10.1021/nl0719832     Document Type: Article

References (39)

1. Alivisatos, P. Nat. Biotechnol 2004, 22, 47.
2. Smith, A. M.; Dave, S.; Nie, S.; True, L.; Gao, X. Expert Rev. Mol. Diagn. 2006, 6, 231.
3. Smith, A. M.; Ruan, G.; Rhyner, M. N.; Nie, S. Ann. Biomed. Eng. 2006, 34, 3.
4. Alivisatos, A. P.; Gu, W.; Larabell, C. Annu. Rev. Biomed. Eng. 2005, 7, 55.
5. Sukhanova, A.; et al. Anal. Biochem. 2004, 324, 60.
6. Chen, F.; Gerion, D. Nano Lett. 2004, 4, 1827.
7. Jaiswal, J. K.; Matoussi, H.; Mauro, J. M.; Simon, S. M. Nat. Biotechnol. 2003, 21, 47.
8. Knight, V. B.; Serrano, E. E. Proc. SPIE 2006, 6096, 60960Y.
9. Duan, H.; Nie, S. J. Am. Chem. Soc. 2007, 129, 3333.
10. Ryman-Rasmussen, J. P.; Riviere, J. E.; Monteiro-Riviere, N. A. J. Invest. Dermatol. 2007, 127, 143.
11. Shiohara, A.; Hoshino, A.; Hanaki, K.-I.; Suzuki, K.; Yamamoto, K. Microbiol. Immunol. 2004, 48, 669.
12. Lovrić, J.; et al. J. Mol. Med. 2005, 83, 377.
13. Lovrić, J.; et al. Chem. Biol. 2005, 12, 1227.
14. Cho, S. J.; Maysinger, D.; Jain, M.; Roder, B.; Hackbarth, S.; Winnik, F. M. Langmuir 2007, 23, 1974.
15. Cook, A.; Bono, F.; Jinek, M.; Conti, E. Annu. Rev. Biochem. 2007, 76, 647.
16. Murray, S. Nat. Rev. Mol. Cell Biol. 2007, 8, 195.
17. Lusk, C. P.; Blobel, G.; King, M. C Nat. Rev. Mol. Cell Biol. 2007, 8, 414.
18. Mukherjee, S.; Ghosh, R. N.; Maxfield, F. R. Physiol. Rev. 1997, 77, 759.
19. Boussif, O.; Lezoualc'h, F.; Zanta, M. A.; Mergny, M. D.; Scherman, D.; Demeneix, B.; Behr, J. P. Proc. Natl. Acad. Sci. U.S.A. 1995, 92, 7297.
20. Panyam, J.; Zhou, W. Z.; Prabha, S.; Sahoo, S. K.; Labhasetwar, V. FASEB J. 2002, 16, 1217.
21. Stolnik, S.; Garnett, M. C.; Davies, M. C.; Ilium, L.; Bousta, M.; Vert, M.; Davis, S. S. Colloids Surf., A 1995, 97, 235.
22. Susha, A. S.; Javier, A. M.; Parak, W. J.; Rogach, A. L. Colloids Surf., A 2006, 281, 40.
23. Gao, M.; Kirstein, S.; Mölhwald, H.; Rogach, A. L.; Kornowski, A.; Eychmüller, A.; Weller, H. J. Phys. Chem. B 1998, 102, 8360.
24. Shitara, Y.; Kato, Y.; Sugiyama, Y. J. Controlled Release 1998, 55, 35.
25. Perez-Terzic, C.; Pyle, J.; Jaconi, M.; Stehno-Bittel, L.; Clapham, D. E. Science 1996, 273, 1875.
26. Information on size of commercially available Qdot samples of the Invitrogen Corporation: http://probes.invitrogen.com/products/qdot/.
27. Baranov, A.; et al. Phys. Rev. B 2003, 68, 1653061.
28. Aderem, A.; Underhill, D. M. Annu. Rev. Immunol. 1999, 17, 593.
29. Vosper, H.; et al. J. Biol. Chem. 2001, 276, 44258.
30. Iwashima, Y.; et al. Biochem. Biophys. Res. Commun. 2000, 277, 368.
31. Metz, S.; et al. Eur. Radiol. 2006, 16, 598.
32. Greenspan, P.; Ryu, B. H.; Mao, F.; Gutman, R. L. Biochim. Biophys. Acta 1995, 1257, 257.
33. Magnusson, K. E.; Stendahl, O.; Stjernstrom, I.; Edebo, L. Immunology 1979, 36, 439.
34. Kilhstrom, E. Am. J. Clin. Nutr. 1980, 33, 2491.
35. Vyas, J. M.; Kim, Y. M.; Artavanis-Tsakonas, K.; Love, J. C.; Van der Veen, A. G.; Ploegh, H. L. J. Immunol. 2007, 178, 7199.
36. Mazzanti, M.; Bustamante, J. O.; Oberleithner, H. Physiol. Rev. 2001, 81, 1.
37. Jenuwein, T.; Allis, C. D. Science 2001, 293, 1074.
38. Gaponik, N.; et al. J. Phys. Chem. B 2002, 106, 7177.
39. Rogach, A. L.; Franzl, T.; Klar, T. A.; Feldmann, J.; Gaponik, N.; Lesnyak, V.; Shavel, A.; Eychmüller, A.; Rakovich, Y. P.; Donegan, J. F. J. Phys. Chem. C 2007, 111, 14628.