메뉴 건너뛰기




Volumn 4, Issue SEP, 2013, Pages

Modulation of the endocannabinoid system: Vulnerability factor and new treatment target for stimulant addiction

Author keywords

Addiction; Cannabinoids or endocannabinoids; Cannabis; Cocaine; Psychostimulants; Stimulants

Indexed keywords

1 (2,3 DICHLOROBENZOYL) 5 METHOXY 2 METHYL 3 (2 MORPHOLINOETHYL)INDOLE; 1 (2,4 DICHLOROPHENYL) 5 (4 IODOPHENYL) 4 METHYL N (1 PIPERIDYL) 1H PYRAZOLE 3 CARBOXAMIDE; 1 DEOXY 3 (1,1 DIMETHYLBUTYL) DELTA8 TETRAHYDROCANNABINOL; 2 ARACHIDONOYLGLYCEROL; 2,3 DIHYDRO 5 METHYL 3 (MORPHOLINOMETHYL) 6 (1 NAPHTHOYL)PYRROLO[1,2,3 DE][1,4]BENZOXAZINE; 4 (1,1 DIMETHYLHEPTYL) 1',2',3',4',5',6' HEXAHYDRO 2,3' DIHYDROXY 6' (3 HYDROXYPROPYL)BIPHENYL; ACYLGLYCEROL LIPASE; AMPHETAMINE; ANALGESIC AGENT; ANANDAMIDE; CANNABIDIOL; CANNABINOID 1 RECEPTOR; CANNABINOID 2 RECEPTOR; CANNABIS; COCAINE; CYCLOHEXYLCARBAMIC ACID 3' CARBAMOYLBIPHENYL 3 YL ESTER; DEXANABINOL; DRONABINOL; ENDOCANNABINOID; FATTY ACID AMIDASE; G PROTEIN COUPLED RECEPTOR; JZL 184; KETAMINE; N (4 HYDROXYPHENYL)ARACHIDONAMIDE; NEUROTRANSMITTER; PF 3845; PSYCHOSTIMULANT AGENT; RIMONABANT; UNCLASSIFIED DRUG; UNINDEXED DRUG; VANILLOID RECEPTOR 1;

EID: 84885349034     PISSN: None     EISSN: 16640640     Source Type: Journal    
DOI: 10.3389/fpsyt.2013.00109     Document Type: Article
Times cited : (38)

References (294)
  • 1
    • 77149172889 scopus 로고    scopus 로고
    • UNODC, Vienna: United Nations Office on Drugs and Crime
    • UNODC. World Drug Report 2009. Vienna: United Nations Office on Drugs and Crime (2009).
    • (2009) World Drug Report 2009
  • 3
    • 84855475193 scopus 로고    scopus 로고
    • Extent of illicit drug use and dependence, and their contribution to the global burden of disease
    • doi:10.1016/S0140-6736(11)61138-0
    • Degenhardt L, Hall W. Extent of illicit drug use and dependence, and their contribution to the global burden of disease. Lancet (2012) 379:55-70. doi:10.1016/S0140-6736(11)61138-0.
    • (2012) Lancet , vol.379 , pp. 55-70
    • Degenhardt, L.1    Hall, W.2
  • 4
    • 0003992201 scopus 로고    scopus 로고
    • UNODC, Vienna: United Nations Publication
    • UNODC. World Drug Report. Vienna: United Nations Publication (2012).
    • (2012) World Drug Report
  • 5
    • 0034603568 scopus 로고    scopus 로고
    • Chief health risks associated with intravenous heroin and cocaine abuse
    • Ben Diane MK, Feroni I, Poncet M, Obadia Y. Chief health risks associated with intravenous heroin and cocaine abuse. Presse Med (2000) 29:453-7.
    • (2000) Presse Med , vol.29 , pp. 453-457
    • Ben Diane, M.K.1    Feroni, I.2    Poncet, M.3    Obadia, Y.4
  • 6
    • 79952700576 scopus 로고    scopus 로고
    • Mortality among individuals with cannabis, cocaine, amphetamine, MDMA, and opioid use disorders: a nationwide follow-up study of Danish substance users in treatment
    • doi:10.1016/j.drugalcdep.2010.09.013
    • Arendt M, Munk-Jorgensen P, Sher L, Jensen SO. Mortality among individuals with cannabis, cocaine, amphetamine, MDMA, and opioid use disorders: a nationwide follow-up study of Danish substance users in treatment. Drug Alcohol Depend (2011) 114(2-3):134-9. doi:10.1016/j.drugalcdep.2010.09.013.
    • (2011) Drug Alcohol Depend , vol.114 , Issue.2-3 , pp. 134-139
    • Arendt, M.1    Munk-Jorgensen, P.2    Sher, L.3    Jensen, S.O.4
  • 7
    • 79960312586 scopus 로고    scopus 로고
    • Cocaine-related medical and trauma problems: a consecutive series of 743 patients from a multicentre study in Italy
    • doi:10.1097/MEJ.0b013e3283440f25
    • Pavarin R, Lugoboni F, Mathewson S, Ferrari AM, Guizzardi G, Quaglio G. Cocaine-related medical and trauma problems: a consecutive series of 743 patients from a multicentre study in Italy. Eur J Emerg Med (2011) 18(4):208-14. doi:10.1097/MEJ.0b013e3283440f25.
    • (2011) Eur J Emerg Med , vol.18 , Issue.4 , pp. 208-214
    • Pavarin, R.1    Lugoboni, F.2    Mathewson, S.3    Ferrari, A.M.4    Guizzardi, G.5    Quaglio, G.6
  • 8
    • 3242755117 scopus 로고    scopus 로고
    • Agents in development for the management of cocaine abuse
    • doi:10.2165/00003495-200464140-00004
    • Gorelick DA, Gardner EL, Xi ZX. Agents in development for the management of cocaine abuse. Drugs (2004) 64:1547-73. doi:10.2165/00003495-200464140-00004.
    • (2004) Drugs , vol.64 , pp. 1547-1573
    • Gorelick, D.A.1    Gardner, E.L.2    Xi, Z.X.3
  • 9
    • 17844408702 scopus 로고    scopus 로고
    • Pharmacotherapy and other treatments for cocaine abuse and dependence
    • doi:10.1097/01.yco.0000165596.98552.02
    • Vocci FJ, Elkashef A. Pharmacotherapy and other treatments for cocaine abuse and dependence. Curr Opin Psychiatry (2005) 18:265-70. doi:10.1097/01.yco.0000165596.98552.02.
    • (2005) Curr Opin Psychiatry , vol.18 , pp. 265-270
    • Vocci, F.J.1    Elkashef, A.2
  • 11
    • 84879829682 scopus 로고    scopus 로고
    • Rational development of addiction pharmacotherapies: successes, failures, and prospects
    • doi:10.1101/cshperspect.a012880
    • Christopher Pierce R, O'Brien CP, Kenny PJ, Vanderschuren LJ. Rational development of addiction pharmacotherapies: successes, failures, and prospects. Cold Spring Harb Perspect Med (2012) 2:a012880. doi:10.1101/cshperspect.a012880.
    • (2012) Cold Spring Harb Perspect Med , vol.2
    • Christopher Pierce, R.1    O'Brien, C.P.2    Kenny, P.J.3    Vanderschuren, L.J.4
  • 15
    • 67349196145 scopus 로고    scopus 로고
    • Hypothesis-driven medication discovery for the treatment of psychostimulant addiction
    • doi:10.2174/1874473710801030303
    • Xi ZX, Gardner EL. Hypothesis-driven medication discovery for the treatment of psychostimulant addiction. Curr Drug Abuse Rev (2008) 1:303-27. doi:10.2174/1874473710801030303.
    • (2008) Curr Drug Abuse Rev , vol.1 , pp. 303-327
    • Xi, Z.X.1    Gardner, E.L.2
  • 16
    • 78951469965 scopus 로고    scopus 로고
    • Efficacy of indirect dopamine agonists for psychostimulant dependence: a systematic review and meta-analysis of randomized controlled trials
    • doi:10.1016/j.jsat.2010.08.012
    • Perez-Mana C, Castells X, Vidal X, Casas M, Capella D. Efficacy of indirect dopamine agonists for psychostimulant dependence: a systematic review and meta-analysis of randomized controlled trials. J Subst Abuse Treat (2011) 40:109-22. doi:10.1016/j.jsat.2010.08.012.
    • (2011) J Subst Abuse Treat , vol.40 , pp. 109-122
    • Perez-Mana, C.1    Castells, X.2    Vidal, X.3    Casas, M.4    Capella, D.5
  • 17
    • 70349690285 scopus 로고    scopus 로고
    • Cocaine vaccine for the treatment of cocaine dependence in methadone-maintained patients: a randomized, double-blind, placebo-controlled efficacy trial
    • doi:10.1001/archgenpsychiatry.2009.128
    • Martell BA, Orson FM, Poling J, Mitchell E, Rossen RD, Gardner T, et al. Cocaine vaccine for the treatment of cocaine dependence in methadone-maintained patients: a randomized, double-blind, placebo-controlled efficacy trial. Arch Gen Psychiatry (2009) 66:1116-23. doi:10.1001/archgenpsychiatry.2009.128.
    • (2009) Arch Gen Psychiatry , vol.66 , pp. 1116-1123
    • Martell, B.A.1    Orson, F.M.2    Poling, J.3    Mitchell, E.4    Rossen, R.D.5    Gardner, T.6
  • 19
    • 20444398090 scopus 로고    scopus 로고
    • Endocannabinoid signaling system and brain reward: emphasis on dopamine
    • doi:10.1016/j.pbb.2005.01.032
    • Gardner EL. Endocannabinoid signaling system and brain reward: emphasis on dopamine. Pharmacol Biochem Behav (2005) 81:263-84. doi:10.1016/j.pbb.2005.01.032.
    • (2005) Pharmacol Biochem Behav , vol.81 , pp. 263-284
    • Gardner, E.L.1
  • 20
    • 67651173255 scopus 로고    scopus 로고
    • Endocannabinoid signaling and long-term synaptic plasticity
    • doi:10.1146/annurev.physiol.010908.163149
    • Heifets BD, Castillo PE. Endocannabinoid signaling and long-term synaptic plasticity. Annu Rev Physiol (2009) 71:283-306. doi:10.1146/annurev.physiol.010908.163149.
    • (2009) Annu Rev Physiol , vol.71 , pp. 283-306
    • Heifets, B.D.1    Castillo, P.E.2
  • 21
    • 59349084762 scopus 로고    scopus 로고
    • Endocannabinoid signals in the control of emotion
    • doi:10.1016/j.coph.2008.12.001
    • Lutz B. Endocannabinoid signals in the control of emotion. Curr Opin Pharmacol (2009) 9:46-52. doi:10.1016/j.coph.2008.12.001.
    • (2009) Curr Opin Pharmacol , vol.9 , pp. 46-52
    • Lutz, B.1
  • 22
    • 77951096725 scopus 로고    scopus 로고
    • Cannabis use correlates of syringe sharing among injection drug users
    • doi:10.1111/j.1521-0391.2010.00031.x
    • Jutras-Aswad D, Zang G, Bruneau J. Cannabis use correlates of syringe sharing among injection drug users. Am J Addict (2010) 19:231-7. doi:10.1111/j.1521-0391.2010.00031.x.
    • (2010) Am J Addict , vol.19 , pp. 231-237
    • Jutras-Aswad, D.1    Zang, G.2    Bruneau, J.3
  • 24
    • 34250803880 scopus 로고    scopus 로고
    • Stress and drug-cue-induced craving in opioid-dependent individuals in naltrexone treatment
    • doi:10.1037/1064-1297.15.2.134
    • Hyman SM, Fox H, Hong KI, Doebrick C, Sinha R. Stress and drug-cue-induced craving in opioid-dependent individuals in naltrexone treatment. Exp Clin Psychopharmacol (2007) 15:134-43. doi:10.1037/1064-1297.15.2.134.
    • (2007) Exp Clin Psychopharmacol , vol.15 , pp. 134-143
    • Hyman, S.M.1    Fox, H.2    Hong, K.I.3    Doebrick, C.4    Sinha, R.5
  • 25
    • 0031914485 scopus 로고    scopus 로고
    • Conditioning factors in drug abuse: can they explain compulsion?
    • doi:10.1177/026988119801200103
    • O'Brien CP, Childress AR, Ehrman R, Robbins SJ. Conditioning factors in drug abuse: can they explain compulsion? J Psychopharmacol (1998) 12:15-22. doi:10.1177/026988119801200103.
    • (1998) J Psychopharmacol , vol.12 , pp. 15-22
    • O'Brien, C.P.1    Childress, A.R.2    Ehrman, R.3    Robbins, S.J.4
  • 26
    • 27744493937 scopus 로고    scopus 로고
    • Neural activity associated with stress-induced cocaine craving: a functional magnetic resonance imaging study
    • doi:10.1007/s00213-005-0147-8
    • Sinha R, Lacadie C, Skudlarski P, Fulbright RK, Rounsaville BJ, Kosten TR, et al. Neural activity associated with stress-induced cocaine craving: a functional magnetic resonance imaging study. Psychopharmacology (Berl) (2005) 183:171-80. doi:10.1007/s00213-005-0147-8.
    • (2005) Psychopharmacology (Berl) , vol.183 , pp. 171-180
    • Sinha, R.1    Lacadie, C.2    Skudlarski, P.3    Fulbright, R.K.4    Rounsaville, B.J.5    Kosten, T.R.6
  • 28
    • 0013249385 scopus 로고    scopus 로고
    • Addiction
    • doi:10.1146/annurev.psych.54.101601.145237
    • Robinson TE, Berridge KC. Addiction. Annu Rev Psychol (2003) 54:25-53. doi:10.1146/annurev.psych.54.101601.145237.
    • (2003) Annu Rev Psychol , vol.54 , pp. 25-53
    • Robinson, T.E.1    Berridge, K.C.2
  • 29
    • 17644374100 scopus 로고    scopus 로고
    • The neural basis of addiction: a pathology of motivation and choice
    • doi:10.1176/appi.ajp.162.8.1403
    • Kalivas PW, Volkow ND. The neural basis of addiction: a pathology of motivation and choice. Am J Psychiatry (2005) 162:1403-13. doi:10.1176/appi.ajp.162.8.1403.
    • (2005) Am J Psychiatry , vol.162 , pp. 1403-1413
    • Kalivas, P.W.1    Volkow, N.D.2
  • 30
    • 51449122303 scopus 로고    scopus 로고
    • Review. Neural mechanisms underlying the vulnerability to develop compulsive drug-seeking habits and addiction
    • doi:10.1098/rstb.2008.0089
    • Everitt BJ, Belin D, Economidou D, Pelloux Y, Dalley JW, Robbins TW. Review. Neural mechanisms underlying the vulnerability to develop compulsive drug-seeking habits and addiction. Philos Trans R Soc Lond B Biol Sci (2008) 363:3125-35. doi:10.1098/rstb.2008.0089.
    • (2008) Philos Trans R Soc Lond B Biol Sci , vol.363 , pp. 3125-3135
    • Everitt, B.J.1    Belin, D.2    Economidou, D.3    Pelloux, Y.4    Dalley, J.W.5    Robbins, T.W.6
  • 31
    • 43449130075 scopus 로고    scopus 로고
    • The neurocircuitry of addiction: an overview
    • doi:10.1038/bjp.2008.51
    • Feltenstein MW, See RE. The neurocircuitry of addiction: an overview. Br J Pharmacol (2008) 154:261-74. doi:10.1038/bjp.2008.51.
    • (2008) Br J Pharmacol , vol.154 , pp. 261-274
    • Feltenstein, M.W.1    See, R.E.2
  • 32
    • 67651153041 scopus 로고    scopus 로고
    • The D(3) dopamine receptor inhibits dopamine release in PC-12/hD3 cells by autoreceptor signaling via PP-2B, CK1, and Cdk-5
    • doi:10.1111/j.1471-4159.2009.06209.x
    • Chen PC, Lao CL, Chen JC. The D(3) dopamine receptor inhibits dopamine release in PC-12/hD3 cells by autoreceptor signaling via PP-2B, CK1, and Cdk-5. J Neurochem (2009) 110:1180-90. doi:10.1111/j.1471-4159.2009.06209.x.
    • (2009) J Neurochem , vol.110 , pp. 1180-1190
    • Chen, P.C.1    Lao, C.L.2    Chen, J.C.3
  • 33
    • 0037010770 scopus 로고    scopus 로고
    • Nucleus accumbens shell and core dopamine: differential role in behavior and addiction
    • doi:10.1016/S0166-4328(02)00286-3
    • Di Chiara G. Nucleus accumbens shell and core dopamine: differential role in behavior and addiction. Behav Brain Res (2002) 137:75-114. doi:10.1016/S0166-4328(02)00286-3.
    • (2002) Behav Brain Res , vol.137 , pp. 75-114
    • Di Chiara, G.1
  • 34
    • 0030802011 scopus 로고    scopus 로고
    • Lesions of the basolateral amygdala abolish the ability of drug associated cues to reinstate responding during withdrawal from self-administered cocaine
    • doi:10.1016/S0166-4328(96)02270-X
    • Meil WM, See RE. Lesions of the basolateral amygdala abolish the ability of drug associated cues to reinstate responding during withdrawal from self-administered cocaine. Behav Brain Res (1997) 87:139-48. doi:10.1016/S0166-4328(96)02270-X.
    • (1997) Behav Brain Res , vol.87 , pp. 139-148
    • Meil, W.M.1    See, R.E.2
  • 36
    • 51449116801 scopus 로고    scopus 로고
    • Introduction. The neurobiology of drug addiction: new vistas
    • doi:10.1098/rstb.2008.0108
    • Robbins TW, Everitt BJ, Nutt DJ. Introduction. The neurobiology of drug addiction: new vistas. Philos Trans R Soc Lond B Biol Sci (2008) 363:3109-11. doi:10.1098/rstb.2008.0108.
    • (2008) Philos Trans R Soc Lond B Biol Sci , vol.363 , pp. 3109-3111
    • Robbins, T.W.1    Everitt, B.J.2    Nutt, D.J.3
  • 37
    • 0036787356 scopus 로고    scopus 로고
    • Drug addiction and its underlying neurobiological basis: neuroimaging evidence for the involvement of the frontal cortex
    • doi:10.1176/appi.ajp.159.10.1642
    • Goldstein RZ, Volkow ND. Drug addiction and its underlying neurobiological basis: neuroimaging evidence for the involvement of the frontal cortex. Am J Psychiatry (2002) 159:1642-52. doi:10.1176/appi.ajp.159.10.1642.
    • (2002) Am J Psychiatry , vol.159 , pp. 1642-1652
    • Goldstein, R.Z.1    Volkow, N.D.2
  • 38
    • 0024209765 scopus 로고
    • The functional output of the mesolimbic dopamine system
    • doi:10.1111/j.1749-6632.1988.tb42108.x
    • Koob GF, Swerdlow NR. The functional output of the mesolimbic dopamine system. Ann N Y Acad Sci (1988) 537:216-27. doi:10.1111/j.1749-6632.1988.tb42108.x.
    • (1988) Ann N Y Acad Sci , vol.537 , pp. 216-227
    • Koob, G.F.1    Swerdlow, N.R.2
  • 39
    • 0030995126 scopus 로고    scopus 로고
    • Relationship between subjective effects of cocaine and dopamine transporter occupancy
    • doi:10.1038/386827a0
    • Volkow ND, Wang GJ, Fischman MW, Foltin RW, Fowler JS, Abumrad NN, et al. Relationship between subjective effects of cocaine and dopamine transporter occupancy. Nature (1997) 386:827-30. doi:10.1038/386827a0.
    • (1997) Nature , vol.386 , pp. 827-830
    • Volkow, N.D.1    Wang, G.J.2    Fischman, M.W.3    Foltin, R.W.4    Fowler, J.S.5    Abumrad, N.N.6
  • 40
    • 0034966465 scopus 로고    scopus 로고
    • 11 Cocaine: PET studies of cocaine pharmacokinetics, dopamine transporter availability and dopamine transporter occupancy
    • doi:10.1016/S0969-8051(01)00211-6
    • Fowler JS, Volkow ND, Wang GJ, Gatley SJ, Logan J. [(11)]Cocaine: PET studies of cocaine pharmacokinetics, dopamine transporter availability and dopamine transporter occupancy. Nucl Med Biol (2001) 28:561-72. doi:10.1016/S0969-8051(01)00211-6.
    • (2001) Nucl Med Biol , vol.28 , pp. 561-572
    • Fowler, J.S.1    Volkow, N.D.2    Wang, G.J.3    Gatley, S.J.4    Logan, J.5
  • 41
    • 0034613214 scopus 로고    scopus 로고
    • Differential effects of stimulants on monoaminergic transporters: pharmacological consequences and implications for neurotoxicity
    • doi:10.1016/S0014-2999(00)00639-7
    • Fleckenstein AE, Gibb JW, Hanson GR. Differential effects of stimulants on monoaminergic transporters: pharmacological consequences and implications for neurotoxicity. Eur J Pharmacol (2000) 406:1-13. doi:10.1016/S0014-2999(00)00639-7.
    • (2000) Eur J Pharmacol , vol.406 , pp. 1-13
    • Fleckenstein, A.E.1    Gibb, J.W.2    Hanson, G.R.3
  • 42
    • 0242576358 scopus 로고    scopus 로고
    • Monoamine transporters and psychostimulant drugs
    • doi:10.1016/j.ejphar.2003.08.054
    • Rothman RB, Baumann MH. Monoamine transporters and psychostimulant drugs. Eur J Pharmacol (2003) 479:23-40. doi:10.1016/j.ejphar.2003.08.054.
    • (2003) Eur J Pharmacol , vol.479 , pp. 23-40
    • Rothman, R.B.1    Baumann, M.H.2
  • 43
    • 0027364736 scopus 로고
    • From synapse to vesicle: the reuptake and storage of biogenic amine neurotransmitters
    • doi:10.1016/0005-2728(93)90109-S
    • Rudnick G, Clark J. From synapse to vesicle: the reuptake and storage of biogenic amine neurotransmitters. Biochim Biophys Acta (1993) 1144:249-63. doi:10.1016/0005-2728(93)90109-S.
    • (1993) Biochim Biophys Acta , vol.1144 , pp. 249-263
    • Rudnick, G.1    Clark, J.2
  • 44
    • 36849051843 scopus 로고    scopus 로고
    • Monoamine transporters and psychostimulant addiction
    • doi:10.1016/j.bcp.2007.08.003
    • Howell LL, Kimmel HL. Monoamine transporters and psychostimulant addiction. Biochem Pharmacol (2008) 75:196-217. doi:10.1016/j.bcp.2007.08.003.
    • (2008) Biochem Pharmacol , vol.75 , pp. 196-217
    • Howell, L.L.1    Kimmel, H.L.2
  • 47
    • 0032560560 scopus 로고    scopus 로고
    • Cocaine reward models: conditioned place preference can be established in dopamine- and in serotonin-transporter knockout mice
    • doi:10.1073/pnas.95.13.7699
    • Sora I, Wichems C, Takahashi N, Li XF, Zeng Z, Revay R, et al. Cocaine reward models: conditioned place preference can be established in dopamine- and in serotonin-transporter knockout mice. Proc Natl Acad Sci U S A (1998) 95:7699-704. doi:10.1073/pnas.95.13.7699.
    • (1998) Proc Natl Acad Sci U S A , vol.95 , pp. 7699-7704
    • Sora, I.1    Wichems, C.2    Takahashi, N.3    Li, X.F.4    Zeng, Z.5    Revay, R.6
  • 48
    • 0038639618 scopus 로고    scopus 로고
    • Role of the hypothalamic-pituitary-adrenal axis in reinstatement of cocaine-seeking behavior in squirrel monkeys
    • doi:10.1007/s00213-003-1391-4
    • Lee B, Tiefenbacher S, Platt DM, Spealman RD. Role of the hypothalamic-pituitary-adrenal axis in reinstatement of cocaine-seeking behavior in squirrel monkeys. Psychopharmacology (Berl) (2003) 168:177-83. doi:10.1007/s00213-003-1391-4.
    • (2003) Psychopharmacology (Berl) , vol.168 , pp. 177-183
    • Lee, B.1    Tiefenbacher, S.2    Platt, D.M.3    Spealman, R.D.4
  • 49
    • 20444460343 scopus 로고    scopus 로고
    • The role of endocannabinoid transmission in cocaine addiction
    • doi:10.1016/j.pbb.2005.02.015
    • Arnold JC. The role of endocannabinoid transmission in cocaine addiction. Pharmacol Biochem Behav (2005) 81:396-406. doi:10.1016/j.pbb.2005.02.015.
    • (2005) Pharmacol Biochem Behav , vol.81 , pp. 396-406
    • Arnold, J.C.1
  • 50
    • 33645025726 scopus 로고    scopus 로고
    • Ionotropic and metabotropic glutamate receptor antagonism attenuates cue-induced cocaine seeking
    • doi:10.1038/sj.npp.1300845
    • Backstrom P, Hyytia P. Ionotropic and metabotropic glutamate receptor antagonism attenuates cue-induced cocaine seeking. Neuropsychopharmacology (2006) 31:778-86. doi:10.1038/sj.npp.1300845.
    • (2006) Neuropsychopharmacology , vol.31 , pp. 778-786
    • Backstrom, P.1    Hyytia, P.2
  • 51
    • 0037317346 scopus 로고    scopus 로고
    • Neurobiology of addiction and implications for treatment
    • doi:10.1192/bjp.182.2.97
    • Lingford-Hughes A, Nutt D. Neurobiology of addiction and implications for treatment. Br J Psychiatry (2003) 182:97-100. doi:10.1192/bjp.182.2.97.
    • (2003) Br J Psychiatry , vol.182 , pp. 97-100
    • Lingford-Hughes, A.1    Nutt, D.2
  • 52
    • 1842828872 scopus 로고    scopus 로고
    • Cocaine acts on accumbens monoamines and locomotor behavior via a 5-HT2A/2C receptor mechanism as shown by ketanserin: 24-h follow-up studies
    • doi:10.1016/j.pnpbp.2004.01.007
    • Broderick PA, Olabisi OA, Rahni DN, Zhou Y. Cocaine acts on accumbens monoamines and locomotor behavior via a 5-HT2A/2C receptor mechanism as shown by ketanserin: 24-h follow-up studies. Prog Neuropsychopharmacol Biol Psychiatry (2004) 28:547-57. doi:10.1016/j.pnpbp.2004.01.007.
    • (2004) Prog Neuropsychopharmacol Biol Psychiatry , vol.28 , pp. 547-557
    • Broderick, P.A.1    Olabisi, O.A.2    Rahni, D.N.3    Zhou, Y.4
  • 53
    • 18044377578 scopus 로고    scopus 로고
    • Role of serotonin (5-HT)2 receptors in cocaine self-administration and seeking behavior in rats
    • Filip M. Role of serotonin (5-HT)2 receptors in cocaine self-administration and seeking behavior in rats. Pharmacol Rep (2005) 57:35-46.
    • (2005) Pharmacol Rep , vol.57 , pp. 35-46
    • Filip, M.1
  • 54
    • 33645222439 scopus 로고    scopus 로고
    • Role of the increased noradrenergic neurotransmission in drug self-administration
    • doi:10.1016/j.drugalcdep.2005.09.002
    • Wee S, Wang Z, He R, Zhou J, Kozikowski AP, Woolverton WL. Role of the increased noradrenergic neurotransmission in drug self-administration. Drug Alcohol Depend (2006) 82:151-7. doi:10.1016/j.drugalcdep.2005.09.002.
    • (2006) Drug Alcohol Depend , vol.82 , pp. 151-157
    • Wee, S.1    Wang, Z.2    He, R.3    Zhou, J.4    Kozikowski, A.P.5    Woolverton, W.L.6
  • 55
    • 0035942241 scopus 로고    scopus 로고
    • Molecular mechanisms of cocaine reward: combined dopamine and serotonin transporter knockouts eliminate cocaine place preference
    • doi:10.1073/pnas.091039298
    • Sora I, Hall FS, Andrews AM, Itokawa M, Li XF, Wei HB, et al. Molecular mechanisms of cocaine reward: combined dopamine and serotonin transporter knockouts eliminate cocaine place preference. Proc Natl Acad Sci U S A (2001) 98:5300-5. doi:10.1073/pnas.091039298.
    • (2001) Proc Natl Acad Sci U S A , vol.98 , pp. 5300-5305
    • Sora, I.1    Hall, F.S.2    Andrews, A.M.3    Itokawa, M.4    Li, X.F.5    Wei, H.B.6
  • 56
    • 0037110603 scopus 로고    scopus 로고
    • Cocaine mechanisms: enhanced cocaine, fluoxetine and nisoxetine place preferences following monoamine transporter deletions
    • doi:10.1016/S0306-4522(02)00379-2
    • Hall FS, Li XF, Sora I, Xu F, Caron M, Lesch KP, et al. Cocaine mechanisms: enhanced cocaine, fluoxetine and nisoxetine place preferences following monoamine transporter deletions. Neuroscience (2002) 115:153-61. doi:10.1016/S0306-4522(02)00379-2.
    • (2002) Neuroscience , vol.115 , pp. 153-161
    • Hall, F.S.1    Li, X.F.2    Sora, I.3    Xu, F.4    Caron, M.5    Lesch, K.P.6
  • 57
    • 0033850835 scopus 로고    scopus 로고
    • Stress-induced relapse to heroin and cocaine seeking in rats: a review
    • doi:10.1016/S0165-0173(00)00024-2
    • Shaham Y, Erb S, Stewart J. Stress-induced relapse to heroin and cocaine seeking in rats: a review. Brain Res Brain Res Rev (2000) 33:13-33. doi:10.1016/S0165-0173(00)00024-2.
    • (2000) Brain Res Brain Res Rev , vol.33 , pp. 13-33
    • Shaham, Y.1    Erb, S.2    Stewart, J.3
  • 58
    • 34250358317 scopus 로고    scopus 로고
    • There and back again: a tale of norepinephrine and drug addiction
    • doi:10.1038/sj.npp.1301263
    • Weinshenker D, Schroeder JP. There and back again: a tale of norepinephrine and drug addiction. Neuropsychopharmacology (2007) 32:1433-51. doi:10.1038/sj.npp.1301263.
    • (2007) Neuropsychopharmacology , vol.32 , pp. 1433-1451
    • Weinshenker, D.1    Schroeder, J.P.2
  • 59
    • 69749094506 scopus 로고    scopus 로고
    • Mechanisms of disulfiram-induced cocaine abstinence: antabuse and cocaine relapse
    • doi:10.1124/mi.9.4.6
    • Gaval-Cruz M, Weinshenker D. Mechanisms of disulfiram-induced cocaine abstinence: antabuse and cocaine relapse. Mol Interv (2009) 9:175-87. doi:10.1124/mi.9.4.6.
    • (2009) Mol Interv , vol.9 , pp. 175-187
    • Gaval-Cruz, M.1    Weinshenker, D.2
  • 60
    • 0036662881 scopus 로고    scopus 로고
    • Blockade of stress-induced but not cocaine-induced reinstatement by infusion of noradrenergic antagonists into the bed nucleus of the stria terminalis or the central nucleus of the amygdala
    • Leri F, Flores J, Rodaros D, Stewart J. Blockade of stress-induced but not cocaine-induced reinstatement by infusion of noradrenergic antagonists into the bed nucleus of the stria terminalis or the central nucleus of the amygdala. J Neurosci (2002) 22:5713-8.
    • (2002) J Neurosci , vol.22 , pp. 5713-5718
    • Leri, F.1    Flores, J.2    Rodaros, D.3    Stewart, J.4
  • 61
    • 80053563354 scopus 로고    scopus 로고
    • alpha(2) Adrenergic and imidazoline receptor agonists prevent cue-induced cocaine seeking
    • doi:10.1016/j.biopsych.2011.06.010
    • Smith RJ, Aston-Jones G. alpha(2) Adrenergic and imidazoline receptor agonists prevent cue-induced cocaine seeking. Biol Psychiatry (2011) 70:712-9. doi:10.1016/j.biopsych.2011.06.010.
    • (2011) Biol Psychiatry , vol.70 , pp. 712-719
    • Smith, R.J.1    Aston-Jones, G.2
  • 62
    • 0029657999 scopus 로고    scopus 로고
    • Serotonin1b receptor stimulation enhances dopamine-mediated reinforcement
    • doi:10.1007/s002130050120
    • Parsons LH, Weiss F, Koob GF. Serotonin1b receptor stimulation enhances dopamine-mediated reinforcement. Psychopharmacology (Berl) (1996) 128:150-60. doi:10.1007/s002130050120.
    • (1996) Psychopharmacology (Berl) , vol.128 , pp. 150-160
    • Parsons, L.H.1    Weiss, F.2    Koob, G.F.3
  • 63
    • 0038290732 scopus 로고    scopus 로고
    • Glutamatergic mechanisms in addiction
    • doi:10.1038/sj.mp.4001269
    • Tzschentke TM, Schmidt WJ. Glutamatergic mechanisms in addiction. Mol Psychiatry (2003) 8:373-82. doi:10.1038/sj.mp.4001269.
    • (2003) Mol Psychiatry , vol.8 , pp. 373-382
    • Tzschentke, T.M.1    Schmidt, W.J.2
  • 64
    • 58149099399 scopus 로고    scopus 로고
    • Glutamate transmission in addiction
    • doi:10.1016/j.neuropharm.2008.07.011
    • Kalivas PW, Lalumiere RT, Knackstedt L, Shen H. Glutamate transmission in addiction. Neuropharmacology (2009) 56(Suppl 1):169-73. doi:10.1016/j.neuropharm.2008.07.011.
    • (2009) Neuropharmacology , vol.56 , Issue.SUPPL. 1 , pp. 169-173
    • Kalivas, P.W.1    Lalumiere, R.T.2    Knackstedt, L.3    Shen, H.4
  • 65
    • 34547618436 scopus 로고    scopus 로고
    • Acute cocaine exposure alters spine density and long-term potentiation in the ventral tegmental area
    • doi:10.1111/j.1460-9568.2007.05689.x
    • Sarti F, Borgland SL, Kharazia VN, Bonci A. Acute cocaine exposure alters spine density and long-term potentiation in the ventral tegmental area. Eur J Neurosci (2007) 26:749-56. doi:10.1111/j.1460-9568.2007.05689.x.
    • (2007) Eur J Neurosci , vol.26 , pp. 749-756
    • Sarti, F.1    Borgland, S.L.2    Kharazia, V.N.3    Bonci, A.4
  • 66
    • 53749102062 scopus 로고    scopus 로고
    • Neural plasticity and addiction: integrin-linked kinase and cocaine behavioral sensitization
    • doi:10.1111/j.1471-4159.2008.05619.x
    • Chen Q, Xiong X, Lee TH, Liu Y, Wetsel WC, Zhang X. Neural plasticity and addiction: integrin-linked kinase and cocaine behavioral sensitization. J Neurochem (2008) 107:679-89. doi:10.1111/j.1471-4159.2008.05619.x.
    • (2008) J Neurochem , vol.107 , pp. 679-689
    • Chen, Q.1    Xiong, X.2    Lee, T.H.3    Liu, Y.4    Wetsel, W.C.5    Zhang, X.6
  • 67
    • 59349110023 scopus 로고    scopus 로고
    • Glutamate and reinstatement
    • doi:10.1016/j.coph.2008.12.003
    • Knackstedt LA, Kalivas PW. Glutamate and reinstatement. Curr Opin Pharmacol (2009) 9:59-64. doi:10.1016/j.coph.2008.12.003.
    • (2009) Curr Opin Pharmacol , vol.9 , pp. 59-64
    • Knackstedt, L.A.1    Kalivas, P.W.2
  • 68
    • 77956569789 scopus 로고    scopus 로고
    • Incentive learning underlying cocaine-seeking requires mGluR5 receptors located on dopamine D1 receptor-expressing neurons
    • doi:10.1523/JNEUROSCI.2550-10.2010
    • Novak M, Halbout B, O'Connor EC, Rodriguez Parkitna J, Su T, Chai M, et al. Incentive learning underlying cocaine-seeking requires mGluR5 receptors located on dopamine D1 receptor-expressing neurons. J Neurosci (2010) 30:11973-82. doi:10.1523/JNEUROSCI.2550-10.2010.
    • (2010) J Neurosci , vol.30 , pp. 11973-82
    • Novak, M.1    Halbout, B.2    O'Connor, E.C.3    Rodriguez Parkitna, J.4    Su, T.5    Chai, M.6
  • 69
    • 0037743546 scopus 로고    scopus 로고
    • Neuroadaptation in cystine-glutamate exchange underlie cocaine relapse
    • doi:10.1038/nn1069
    • Baker DA, McFarland K, Lake RW, Shen H, Tang XC, Toda S, et al. Neuroadaptation in cystine-glutamate exchange underlie cocaine relapse. Nat Neurosci (2003) 6:743-9. doi:10.1038/nn1069.
    • (2003) Nat Neurosci , vol.6 , pp. 743-749
    • Baker, D.A.1    McFarland, K.2    Lake, R.W.3    Shen, H.4    Tang, X.C.5    Toda, S.6
  • 70
    • 0037693859 scopus 로고    scopus 로고
    • Prefrontal glutamate release into the core of the nucleus accumbens mediates cocaine-induced reinstatement of drug-seeking behavior
    • McFarland K, Lapish CC, Kalivas PW. Prefrontal glutamate release into the core of the nucleus accumbens mediates cocaine-induced reinstatement of drug-seeking behavior. J Neurosci (2003) 23:3531-7.
    • (2003) J Neurosci , vol.23 , pp. 3531-3537
    • McFarland, K.1    Lapish, C.C.2    Kalivas, P.W.3
  • 71
    • 0034256432 scopus 로고    scopus 로고
    • Glutamate transmission in the nucleus accumbens mediates relapse in cocaine addiction
    • Cornish JL, Kalivas PW. Glutamate transmission in the nucleus accumbens mediates relapse in cocaine addiction. J Neurosci (2000) 20:RC89.
    • (2000) J Neurosci , vol.20
    • Cornish, J.L.1    Kalivas, P.W.2
  • 72
    • 1242341999 scopus 로고    scopus 로고
    • Limbic and motor circuitry underlying footshock-induced reinstatement of cocaine-seeking behavior
    • doi:10.1523/JNEUROSCI.4177-03.2004
    • McFarland K, Davidge SB, Lapish CC, Kalivas PW. Limbic and motor circuitry underlying footshock-induced reinstatement of cocaine-seeking behavior. J Neurosci (2004) 24:1551-60. doi:10.1523/JNEUROSCI.4177-03.2004.
    • (2004) J Neurosci , vol.24 , pp. 1551-1560
    • McFarland, K.1    Davidge, S.B.2    Lapish, C.C.3    Kalivas, P.W.4
  • 73
    • 34249883314 scopus 로고    scopus 로고
    • Involvement of AMPA/kainate, NMDA, and mGlu5 receptors in the nucleus accumbens core in cue-induced reinstatement of cocaine seeking in rats
    • doi:10.1007/s00213-007-0753-8
    • Backstrom P, Hyytia P. Involvement of AMPA/kainate, NMDA, and mGlu5 receptors in the nucleus accumbens core in cue-induced reinstatement of cocaine seeking in rats. Psychopharmacology (Berl) (2007) 192:571-80. doi:10.1007/s00213-007-0753-8.
    • (2007) Psychopharmacology (Berl) , vol.192 , pp. 571-580
    • Backstrom, P.1    Hyytia, P.2
  • 74
    • 4644273156 scopus 로고    scopus 로고
    • Dopamine and drug addiction: the nucleus accumbens shell connection
    • doi:10.1016/j.neuropharm.2004.06.032
    • Di Chiara G, Bassareo V, Fenu S, De Luca MA, Spina L, Cadoni C, et al. Dopamine and drug addiction: the nucleus accumbens shell connection. Neuropharmacology (2004) 47(Suppl 1):227-41. doi:10.1016/j.neuropharm.2004.06.032.
    • (2004) Neuropharmacology , vol.47 , Issue.SUPPL. 1 , pp. 227-241
    • Di Chiara, G.1    Bassareo, V.2    Fenu, S.3    De Luca, M.A.4    Spina, L.5    Cadoni, C.6
  • 75
    • 2442701517 scopus 로고    scopus 로고
    • Modulation of two oscillatory networks in the peripheral olfactory system by gamma-aminobutyric acid, glutamate, and acetylcholine in the terrestrial slug Limax marginatus
    • doi:10.1002/neu.10328
    • Ito I, Kimura T, Watanabe S, Kirino Y, Ito E. Modulation of two oscillatory networks in the peripheral olfactory system by gamma-aminobutyric acid, glutamate, and acetylcholine in the terrestrial slug Limax marginatus. J Neurobiol (2004) 59:304-18. doi:10.1002/neu.10328.
    • (2004) J Neurobiol , vol.59 , pp. 304-318
    • Ito, I.1    Kimura, T.2    Watanabe, S.3    Kirino, Y.4    Ito, E.5
  • 76
    • 0035576117 scopus 로고    scopus 로고
    • Differential involvement of NMDA, AMPA/kainate, and dopamine receptors in the nucleus accumbens core in the acquisition and performance of pavlovian approach behavior
    • Di Ciano P, Cardinal RN, Cowell RA, Little SJ, Everitt BJ. Differential involvement of NMDA, AMPA/kainate, and dopamine receptors in the nucleus accumbens core in the acquisition and performance of pavlovian approach behavior. J Neurosci (2001) 21:9471-7.
    • (2001) J Neurosci , vol.21 , pp. 9471-9477
    • Di Ciano, P.1    Cardinal, R.N.2    Cowell, R.A.3    Little, S.J.4    Everitt, B.J.5
  • 77
    • 0038502133 scopus 로고    scopus 로고
    • Brain circuitry and the reinstatement of cocaine-seeking behavior
    • doi:10.1007/s00213-003-1393-2
    • Kalivas PW, McFarland K. Brain circuitry and the reinstatement of cocaine-seeking behavior. Psychopharmacology (Berl) (2003) 168:44-56. doi:10.1007/s00213-003-1393-2.
    • (2003) Psychopharmacology (Berl) , vol.168 , pp. 44-56
    • Kalivas, P.W.1    McFarland, K.2
  • 78
    • 0029995617 scopus 로고    scopus 로고
    • Neurobehavioural mechanisms of reward and motivation
    • doi:10.1016/S0959-4388(96)80077-8
    • Robbins TW, Everitt BJ. Neurobehavioural mechanisms of reward and motivation. Curr Opin Neurobiol (1996) 6:228-36. doi:10.1016/S0959-4388(96)80077-8.
    • (1996) Curr Opin Neurobiol , vol.6 , pp. 228-236
    • Robbins, T.W.1    Everitt, B.J.2
  • 79
    • 0032693376 scopus 로고    scopus 로고
    • Impulsivity resulting from frontostriatal dysfunction in drug abuse: implications for the control of behavior by reward-related stimuli
    • doi:10.1007/PL00005483
    • Jentsch JD, Taylor JR. Impulsivity resulting from frontostriatal dysfunction in drug abuse: implications for the control of behavior by reward-related stimuli. Psychopharmacology (Berl) (1999) 146:373-90. doi:10.1007/PL00005483.
    • (1999) Psychopharmacology (Berl) , vol.146 , pp. 373-390
    • Jentsch, J.D.1    Taylor, J.R.2
  • 80
    • 1542375848 scopus 로고    scopus 로고
    • Distinct portions of anterior cingulate cortex and medial prefrontal cortex are activated by reward processing in separable phases of decision-making cognition
    • doi:10.1016/j.biopsych.2003.11.012
    • Rogers RD, Ramnani N, Mackay C, Wilson JL, Jezzard P, Carter CS, et al. Distinct portions of anterior cingulate cortex and medial prefrontal cortex are activated by reward processing in separable phases of decision-making cognition. Biol Psychiatry (2004) 55:594-602. doi:10.1016/j.biopsych.2003.11.012.
    • (2004) Biol Psychiatry , vol.55 , pp. 594-602
    • Rogers, R.D.1    Ramnani, N.2    Mackay, C.3    Wilson, J.L.4    Jezzard, P.5    Carter, C.S.6
  • 81
    • 31344469688 scopus 로고    scopus 로고
    • Differences in impulsivity and sensation seeking between early- and late-onsetalcoholics
    • doi:10.1016/j.addbeh.2005.05.009
    • Dom G, Hulstijn W, Sabbe B. Differences in impulsivity and sensation seeking between early- and late-onsetalcoholics. Addict Behav (2006) 31:298-308. doi:10.1016/j.addbeh.2005.05.009.
    • (2006) Addict Behav , vol.31 , pp. 298-308
    • Dom, G.1    Hulstijn, W.2    Sabbe, B.3
  • 82
    • 33847232247 scopus 로고    scopus 로고
    • Neurocognitive and neuroimaging evidence of behavioural dysregulation in human drug addiction: implications for diagnosis, treatment and prevention
    • doi:10.1080/09595230601036978
    • Yucel M, Lubman DI. Neurocognitive and neuroimaging evidence of behavioural dysregulation in human drug addiction: implications for diagnosis, treatment and prevention. Drug Alcohol Rev (2007) 26:33-9. doi:10.1080/09595230601036978.
    • (2007) Drug Alcohol Rev , vol.26 , pp. 33-39
    • Yucel, M.1    Lubman, D.I.2
  • 84
    • 14544299499 scopus 로고    scopus 로고
    • Neural circuits underlying emotional distress in humans
    • doi:10.1196/annals.1314.032
    • Sinha R, Lacadie C, Skudlarski P, Wexler BE. Neural circuits underlying emotional distress in humans. Ann N Y Acad Sci (2004) 1032:254-7. doi:10.1196/annals.1314.032.
    • (2004) Ann N Y Acad Sci , vol.1032 , pp. 254-257
    • Sinha, R.1    Lacadie, C.2    Skudlarski, P.3    Wexler, B.E.4
  • 85
    • 79959746405 scopus 로고    scopus 로고
    • Abnormal structure of frontostriatal brain systems is associated with aspects of impulsivity and compulsivity in cocaine dependence
    • doi:10.1093/brain/awr138
    • Ersche KD, Barnes A, Jones PS, Morein-Zamir S, Robbins TW, Bullmore ET. Abnormal structure of frontostriatal brain systems is associated with aspects of impulsivity and compulsivity in cocaine dependence. Brain (2011) 134:2013-24. doi:10.1093/brain/awr138.
    • (2011) Brain , vol.134 , pp. 2013-2024
    • Ersche, K.D.1    Barnes, A.2    Jones, P.S.3    Morein-Zamir, S.4    Robbins, T.W.5    Bullmore, E.T.6
  • 86
  • 87
    • 0036339410 scopus 로고    scopus 로고
    • Functional neuroanatomy of emotion: a meta-analysis of emotion activation studies in PET and fMRI
    • doi:10.1006/nimg.2002.1087
    • Phan KL, Wager T, Taylor SF, Liberzon I. Functional neuroanatomy of emotion: a meta-analysis of emotion activation studies in PET and fMRI. Neuroimage (2002) 16:331-48. doi:10.1006/nimg.2002.1087.
    • (2002) Neuroimage , vol.16 , pp. 331-348
    • Phan, K.L.1    Wager, T.2    Taylor, S.F.3    Liberzon, I.4
  • 88
    • 0036070782 scopus 로고    scopus 로고
    • Sex differences in depressed substance abusers
    • doi:10.4088/JCP.v63n0715
    • Sinha R, Rounsaville BJ. Sex differences in depressed substance abusers. J Clin Psychiatry (2002) 63:616-27. doi:10.4088/JCP.v63n0715.
    • (2002) J Clin Psychiatry , vol.63 , pp. 616-627
    • Sinha, R.1    Rounsaville, B.J.2
  • 89
    • 35648935483 scopus 로고    scopus 로고
    • Modulation of the endocannabinoid system: therapeutic potential against cocaine dependence
    • doi:10.1016/j.phrs.2007.09.001
    • Tanda G. Modulation of the endocannabinoid system: therapeutic potential against cocaine dependence. Pharmacol Res (2007) 56:406-17. doi:10.1016/j.phrs.2007.09.001.
    • (2007) Pharmacol Res , vol.56 , pp. 406-417
    • Tanda, G.1
  • 90
    • 0342470387 scopus 로고    scopus 로고
    • Therapeutic use of cannabis by crack addicts in Brazil
    • doi:10.1080/02791072.1999.10471776
    • Labigalini E Jr, Rodrigues LR, Da Silveira DX. Therapeutic use of cannabis by crack addicts in Brazil. J Psychoactive Drugs (1999) 31:451-5. doi:10.1080/02791072.1999.10471776.
    • (1999) J Psychoactive Drugs , vol.31 , pp. 451-455
    • Labigalini Jr., E.1    Rodrigues, L.R.2    Da Silveira, D.X.3
  • 91
    • 23344435439 scopus 로고    scopus 로고
    • Postdischarge cannabis use and its relationship to cocaine, alcohol, and heroin use: a prospective study
    • doi:10.1176/appi.ajp.162.8.1507
    • Aharonovich E, Liu X, Samet S, Nunes E, Waxman R, Hasin D. Postdischarge cannabis use and its relationship to cocaine, alcohol, and heroin use: a prospective study. Am J Psychiatry (2005) 162:1507-14. doi:10.1176/appi.ajp.162.8.1507.
    • (2005) Am J Psychiatry , vol.162 , pp. 1507-1514
    • Aharonovich, E.1    Liu, X.2    Samet, S.3    Nunes, E.4    Waxman, R.5    Hasin, D.6
  • 92
    • 33748703859 scopus 로고    scopus 로고
    • The endocannabinoid system as an emerging target of pharmacotherapy
    • doi:10.1124/pr.58.3.2
    • Pacher P, Batkai S, Kunos G. The endocannabinoid system as an emerging target of pharmacotherapy. Pharmacol Rev (2006) 58:389-462. doi:10.1124/pr.58.3.2.
    • (2006) Pharmacol Rev , vol.58 , pp. 389-462
    • Pacher, P.1    Batkai, S.2    Kunos, G.3
  • 94
    • 0025106309 scopus 로고
    • The cannabinoid receptor: biochemical, anatomical and behavioral characterization
    • doi:10.1016/0166-2236(90)90124-S
    • Howlett AC, Bidaut-Russell M, Devane WA, Melvin LS, Johnson MR, Herkenham M. The cannabinoid receptor: biochemical, anatomical and behavioral characterization. Trends Neurosci (1990) 13:420-3. doi:10.1016/0166-2236(90)90124-S.
    • (1990) Trends Neurosci , vol.13 , pp. 420-423
    • Howlett, A.C.1    Bidaut-Russell, M.2    Devane, W.A.3    Melvin, L.S.4    Johnson, M.R.5    Herkenham, M.6
  • 95
    • 0025802871 scopus 로고
    • Neuronal localization of cannabinoid receptors in the basal ganglia of the rat
    • doi:10.1016/0006-8993(91)90970-7
    • Herkenham M, Lynn AB, De Costa BR, Richfield EK. Neuronal localization of cannabinoid receptors in the basal ganglia of the rat. Brain Res (1991) 547:267-74. doi:10.1016/0006-8993(91)90970-7.
    • (1991) Brain Res , vol.547 , pp. 267-274
    • Herkenham, M.1    Lynn, A.B.2    De Costa, B.R.3    Richfield, E.K.4
  • 96
    • 0025954862 scopus 로고
    • Characterization and localization of cannabinoid receptors in rat brain: a quantitative in vitro autoradiographic study
    • Herkenham M, Lynn AB, Johnson MR, Melvin LS, De Costa BR, Rice KC. Characterization and localization of cannabinoid receptors in rat brain: a quantitative in vitro autoradiographic study. J Neurosci (1991) 11:563-83.
    • (1991) J Neurosci , vol.11 , pp. 563-583
    • Herkenham, M.1    Lynn, A.B.2    Johnson, M.R.3    Melvin, L.S.4    De Costa, B.R.5    Rice, K.C.6
  • 97
    • 0034928628 scopus 로고    scopus 로고
    • Endocannabinoids acting at vascular CB1 receptors mediate the vasodilated state in advanced liver cirrhosis
    • doi:10.1038/89953
    • Batkai S, Jarai Z, Wagner JA, Goparaju SK, Varga K, Liu J, et al. Endocannabinoids acting at vascular CB1 receptors mediate the vasodilated state in advanced liver cirrhosis. Nat Med (2001) 7:827-32. doi:10.1038/89953.
    • (2001) Nat Med , vol.7 , pp. 827-832
    • Batkai, S.1    Jarai, Z.2    Wagner, J.A.3    Goparaju, S.K.4    Varga, K.5    Liu, J.6
  • 98
    • 0036867665 scopus 로고    scopus 로고
    • Retrograde signaling in the regulation of synaptic transmission: focus on endocannabinoids
    • doi:10.1016/S0301-0082(02)00080-1
    • Alger BE. Retrograde signaling in the regulation of synaptic transmission: focus on endocannabinoids. Prog Neurobiol (2002) 68:247-86. doi:10.1016/S0301-0082(02)00080-1.
    • (2002) Prog Neurobiol , vol.68 , pp. 247-286
    • Alger, B.E.1
  • 99
    • 18844419446 scopus 로고    scopus 로고
    • Effects of cannabinoids on neurotransmission
    • doi:10.1007/3-540-26573-2_11
    • Szabo B, Schlicker E. Effects of cannabinoids on neurotransmission. Handb Exp Pharmacol (2005) 168:327-65. doi:10.1007/3-540-26573-2_11.
    • (2005) Handb Exp Pharmacol , vol.168 , pp. 327-365
    • Szabo, B.1    Schlicker, E.2
  • 100
    • 33645795765 scopus 로고    scopus 로고
    • Retrograde signalling by endocannabinoids
    • doi:10.1007/3-540-26573-2_12
    • Vaughan CW, Christie MJ. Retrograde signalling by endocannabinoids. Handb Exp Pharmacol (2005) 168:367-83. doi:10.1007/3-540-26573-2_12.
    • (2005) Handb Exp Pharmacol , vol.168 , pp. 367-383
    • Vaughan, C.W.1    Christie, M.J.2
  • 101
    • 58649115375 scopus 로고    scopus 로고
    • Radiosurgery for desmoplastic melanoma of the head and neck using the Leksell Gamma Knife Perfexion technology: a case report
    • doi:10.1159/000195721
    • Kano H, Niranjan A, Novotny J Jr, Bhatnagar J, Flickinger JC, Lunsford LD. Radiosurgery for desmoplastic melanoma of the head and neck using the Leksell Gamma Knife Perfexion technology: a case report. Stereotact Funct Neurosurg (2009) 87:61-5. doi:10.1159/000195721.
    • (2009) Stereotact Funct Neurosurg , vol.87 , pp. 61-65
    • Kano, H.1    Niranjan, A.2    Novotny Jr., J.3    Bhatnagar, J.4    Flickinger, J.C.5    Lunsford, L.D.6
  • 102
    • 0027515373 scopus 로고
    • Molecular characterization of a peripheral receptor for cannabinoids
    • doi:10.1038/365061a0
    • Munro S, Thomas KL, Abu-Shaar M. Molecular characterization of a peripheral receptor for cannabinoids. Nature (1993) 365:61-5. doi:10.1038/365061a0.
    • (1993) Nature , vol.365 , pp. 61-65
    • Munro, S.1    Thomas, K.L.2    Abu-Shaar, M.3
  • 103
    • 0029094470 scopus 로고
    • Expression of central and peripheral cannabinoid receptors in human immune tissues and leukocyte subpopulations
    • doi:10.1111/j.1432-1033.1995.tb20780.x
    • Galiegue S, Mary S, Marchand J, Dussossoy D, Carriere D, Carayon P, et al. Expression of central and peripheral cannabinoid receptors in human immune tissues and leukocyte subpopulations. Eur J Biochem (1995) 232:54-61. doi:10.1111/j.1432-1033.1995.tb20780.x.
    • (1995) Eur J Biochem , vol.232 , pp. 54-61
    • Galiegue, S.1    Mary, S.2    Marchand, J.3    Dussossoy, D.4    Carriere, D.5    Carayon, P.6
  • 104
    • 0037423029 scopus 로고    scopus 로고
    • Milk intake and survival in newborn cannabinoid CB1 receptor knockout mice: evidence for a "CB3" receptor
    • doi:10.1016/S0014-2999(03)01295-0
    • Fride E, Foox A, Rosenberg E, Faigenboim M, Cohen V, Barda L, et al. Milk intake and survival in newborn cannabinoid CB1 receptor knockout mice: evidence for a "CB3" receptor. Eur J Pharmacol (2003) 461:27-34. doi:10.1016/S0014-2999(03)01295-0.
    • (2003) Eur J Pharmacol , vol.461 , pp. 27-34
    • Fride, E.1    Foox, A.2    Rosenberg, E.3    Faigenboim, M.4    Cohen, V.5    Barda, L.6
  • 105
    • 33749544716 scopus 로고    scopus 로고
    • Discovery of the presence and functional expression of cannabinoid CB2 receptors in brain
    • doi:10.1196/annals.1369.052
    • Onaivi ES, Ishiguro H, Gong JP, Patel S, Perchuk A, Meozzi PA, et al. Discovery of the presence and functional expression of cannabinoid CB2 receptors in brain. Ann N Y Acad Sci (2006) 1074:514-36. doi:10.1196/annals.1369.052.
    • (2006) Ann N Y Acad Sci , vol.1074 , pp. 514-536
    • Onaivi, E.S.1    Ishiguro, H.2    Gong, J.P.3    Patel, S.4    Perchuk, A.5    Meozzi, P.A.6
  • 106
    • 34347397535 scopus 로고    scopus 로고
    • The cannabinoid CB2 receptor as a target for inflammation-dependent neurodegeneration
    • doi:10.2174/157015907780866884
    • Ashton JC, Glass M. The cannabinoid CB2 receptor as a target for inflammation-dependent neurodegeneration. Curr Neuropharmacol (2007) 5:73-80. doi:10.2174/157015907780866884.
    • (2007) Curr Neuropharmacol , vol.5 , pp. 73-80
    • Ashton, J.C.1    Glass, M.2
  • 107
    • 45749134610 scopus 로고    scopus 로고
    • Brain neuronal CB2 cannabinoid receptors in drug abuse and depression: from mice to human subjects
    • doi:10.1371/journal.pone.0001640
    • Onaivi ES, Ishiguro H, Gong JP, Patel S, Meozzi PA, Myers L, et al. Brain neuronal CB2 cannabinoid receptors in drug abuse and depression: from mice to human subjects. PLoS ONE (2008) 3:e1640. doi:10.1371/journal.pone.0001640.
    • (2008) PLoS ONE , vol.3
    • Onaivi, E.S.1    Ishiguro, H.2    Gong, J.P.3    Patel, S.4    Meozzi, P.A.5    Myers, L.6
  • 108
    • 1542327667 scopus 로고    scopus 로고
    • P2X7 receptors control 2-arachidonoylglycerol production by microglial cells
    • doi:10.1073/pnas.0306707101
    • Witting A, Walter L, Wacker J, Moller T, Stella N. P2X7 receptors control 2-arachidonoylglycerol production by microglial cells. Proc Natl Acad Sci U S A (2004) 101:3214-9. doi:10.1073/pnas.0306707101.
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 3214-3219
    • Witting, A.1    Walter, L.2    Wacker, J.3    Moller, T.4    Stella, N.5
  • 109
    • 34147165471 scopus 로고    scopus 로고
    • Direct suppression of CNS autoimmune inflammation via the cannabinoid receptor CB1 on neurons and CB2 on autoreactive T cells
    • doi:10.1038/nm1561
    • Maresz K, Pryce G, Ponomarev ED, Marsicano G, Croxford JL, Shriver LP, et al. Direct suppression of CNS autoimmune inflammation via the cannabinoid receptor CB1 on neurons and CB2 on autoreactive T cells. Nat Med (2007) 13:492-7. doi:10.1038/nm1561.
    • (2007) Nat Med , vol.13 , pp. 492-497
    • Maresz, K.1    Pryce, G.2    Ponomarev, E.D.3    Marsicano, G.4    Croxford, J.L.5    Shriver, L.P.6
  • 110
    • 38349091098 scopus 로고    scopus 로고
    • CB2 receptors in the brain: role in central immune function
    • doi:10.1038/sj.bjp.0707584
    • Cabral GA, Raborn ES, Griffin L, Dennis J, Marciano-Cabral F. CB2 receptors in the brain: role in central immune function. Br J Pharmacol (2008) 153:240-51. doi:10.1038/sj.bjp.0707584.
    • (2008) Br J Pharmacol , vol.153 , pp. 240-251
    • Cabral, G.A.1    Raborn, E.S.2    Griffin, L.3    Dennis, J.4    Marciano-Cabral, F.5
  • 112
    • 77952623444 scopus 로고    scopus 로고
    • CB2: a cannabinoid receptor with an identity crisis
    • doi:10.1111/j.1476-5381.2010.00729.x
    • Atwood BK, Mackie K. CB2: a cannabinoid receptor with an identity crisis. Br J Pharmacol (2010) 160:467-79. doi:10.1111/j.1476-5381.2010.00729.x.
    • (2010) Br J Pharmacol , vol.160 , pp. 467-479
    • Atwood, B.K.1    Mackie, K.2
  • 113
    • 77954406421 scopus 로고    scopus 로고
    • Cannabinoid and cannabinoid-like receptors in microglia, astrocytes, and astrocytomas
    • doi:10.1002/glia.20983
    • Stella N. Cannabinoid and cannabinoid-like receptors in microglia, astrocytes, and astrocytomas. Glia (2010) 58:1017-30. doi:10.1002/glia.20983.
    • (2010) Glia , vol.58 , pp. 1017-1030
    • Stella, N.1
  • 114
    • 0036488182 scopus 로고    scopus 로고
    • Neuroprotective properties of cannabinoids against oxidative stress: role of the cannabinoid receptor CB1
    • doi:10.1046/j.0022-3042.2001.00716.x
    • Marsicano G, Moosmann B, Hermann H, Lutz B, Behl C. Neuroprotective properties of cannabinoids against oxidative stress: role of the cannabinoid receptor CB1. J Neurochem (2002) 80:448-56. doi:10.1046/j.0022-3042.2001.00716.x.
    • (2002) J Neurochem , vol.80 , pp. 448-456
    • Marsicano, G.1    Moosmann, B.2    Hermann, H.3    Lutz, B.4    Behl, C.5
  • 116
    • 33646571242 scopus 로고    scopus 로고
    • Immunohistochemical localization of cannabinoid type 1 and vanilloid transient receptor potential vanilloid type 1 receptors in the mouse brain
    • doi:10.1016/j.neuroscience.2006.02.074
    • Cristino L, De Petrocellis L, Pryce G, Baker D, Guglielmotti V, Di Marzo V. Immunohistochemical localization of cannabinoid type 1 and vanilloid transient receptor potential vanilloid type 1 receptors in the mouse brain. Neuroscience (2006) 139:1405-15. doi:10.1016/j.neuroscience.2006.02.074.
    • (2006) Neuroscience , vol.139 , pp. 1405-1415
    • Cristino, L.1    De Petrocellis, L.2    Pryce, G.3    Baker, D.4    Guglielmotti, V.5    Di Marzo, V.6
  • 117
    • 33845306782 scopus 로고    scopus 로고
    • Low-carb diets, fasting and euphoria: is there a link between ketosis and gamma-hydroxybutyrate (GHB)?
    • doi:10.1016/j.mehy.2006.07.043
    • Brown AJ. Low-carb diets, fasting and euphoria: is there a link between ketosis and gamma-hydroxybutyrate (GHB)? Med Hypotheses (2007) 68:268-71. doi:10.1016/j.mehy.2006.07.043.
    • (2007) Med Hypotheses , vol.68 , pp. 268-271
    • Brown, A.J.1
  • 118
    • 59149092768 scopus 로고    scopus 로고
    • The endogenous brain constituent N-arachidonoyl L-serine is an activator of large conductance Ca2+-activated K+ channels
    • doi:10.1124/jpet.108.144717
    • Godlewski G, Offertaler L, Osei-Hyiaman D, Mo FM, Harvey-White J, Liu J, et al. The endogenous brain constituent N-arachidonoyl L-serine is an activator of large conductance Ca2+-activated K+ channels. J Pharmacol Exp Ther (2009) 328:351-61. doi:10.1124/jpet.108.144717.
    • (2009) J Pharmacol Exp Ther , vol.328 , pp. 351-361
    • Godlewski, G.1    Offertaler, L.2    Osei-Hyiaman, D.3    Mo, F.M.4    Harvey-White, J.5    Liu, J.6
  • 119
    • 35648959293 scopus 로고    scopus 로고
    • The novel endocannabinoid receptor GPR55 is activated by atypical cannabinoids but does not mediate their vasodilator effects
    • doi:10.1038/sj.bjp.0707419
    • Johns DG, Behm DJ, Walker DJ, Ao Z, Shapland EM, Daniels DA, et al. The novel endocannabinoid receptor GPR55 is activated by atypical cannabinoids but does not mediate their vasodilator effects. Br J Pharmacol (2007) 152:825-31. doi:10.1038/sj.bjp.0707419.
    • (2007) Br J Pharmacol , vol.152 , pp. 825-831
    • Johns, D.G.1    Behm, D.J.2    Walker, D.J.3    Ao, Z.4    Shapland, E.M.5    Daniels, D.A.6
  • 120
    • 34347352212 scopus 로고    scopus 로고
    • Mutation studies of Ser7.39 and Ser2.60 in the human CB1 cannabinoid receptor: evidence for a serine-induced bend in CB1 transmembrane helix 7
    • doi:10.1124/mol.107.034645
    • Kapur A, Hurst DP, Fleischer D, Whitnell R, Thakur GA, Makriyannis A, et al. Mutation studies of Ser7.39 and Ser2.60 in the human CB1 cannabinoid receptor: evidence for a serine-induced bend in CB1 transmembrane helix 7. Mol Pharmacol (2007) 71:1512-24. doi:10.1124/mol.107.034645.
    • (2007) Mol Pharmacol , vol.71 , pp. 1512-1524
    • Kapur, A.1    Hurst, D.P.2    Fleischer, D.3    Whitnell, R.4    Thakur, G.A.5    Makriyannis, A.6
  • 121
    • 35649015179 scopus 로고    scopus 로고
    • The orphan receptor GPR55 is a novel cannabinoid receptor
    • doi:10.1038/sj.bjp.0707460
    • Ryberg E, Larsson N, Sjogren S, Hjorth S, Hermansson NO, Leonova J, et al. The orphan receptor GPR55 is a novel cannabinoid receptor. Br J Pharmacol (2007) 152:1092-101. doi:10.1038/sj.bjp.0707460.
    • (2007) Br J Pharmacol , vol.152 , pp. 1092-1101
    • Ryberg, E.1    Larsson, N.2    Sjogren, S.3    Hjorth, S.4    Hermansson, N.O.5    Leonova, J.6
  • 122
    • 84862870462 scopus 로고    scopus 로고
    • New insights on endocannabinoid transmission in psychomotor disorders
    • doi:10.1016/j.pnpbp.2012.04.002
    • Giuffrida A, Seillier A. New insights on endocannabinoid transmission in psychomotor disorders. Prog Neuropsychopharmacol Biol Psychiatry (2012) 38:51-8. doi:10.1016/j.pnpbp.2012.04.002.
    • (2012) Prog Neuropsychopharmacol Biol Psychiatry , vol.38 , pp. 51-58
    • Giuffrida, A.1    Seillier, A.2
  • 123
    • 84875548200 scopus 로고    scopus 로고
    • Cannabinoid- and lysophosphatidylinositol-sensitive receptor GPR55 boosts neurotransmitter release at central synapses
    • doi:10.1073/pnas.1211204110
    • Sylantyev S, Jensen TP, Ross RA, Rusakov DA. Cannabinoid- and lysophosphatidylinositol-sensitive receptor GPR55 boosts neurotransmitter release at central synapses. Proc Natl Acad Sci U S A (2013) 110:5193-8. doi:10.1073/pnas.1211204110.
    • (2013) Proc Natl Acad Sci U S A , vol.110 , pp. 5193-5198
    • Sylantyev, S.1    Jensen, T.P.2    Ross, R.A.3    Rusakov, D.A.4
  • 124
    • 58149200910 scopus 로고    scopus 로고
    • Transient receptor potential channels: targeting pain at the source
    • doi:10.1038/nrd2757
    • Patapoutian A, Tate S, Woolf CJ. Transient receptor potential channels: targeting pain at the source. Nat Rev Drug Discov (2009) 8:55-68. doi:10.1038/nrd2757.
    • (2009) Nat Rev Drug Discov , vol.8 , pp. 55-68
    • Patapoutian, A.1    Tate, S.2    Woolf, C.J.3
  • 125
    • 0034724402 scopus 로고    scopus 로고
    • Distribution of mRNA for vanilloid receptor subtype 1 (VR1), and VR1-like immunoreactivity, in the central nervous system of the rat and human
    • doi:10.1073/pnas.97.7.3655
    • Mezey E, Toth ZE, Cortright DN, Arzubi MK, Krause JE, Elde R, et al. Distribution of mRNA for vanilloid receptor subtype 1 (VR1), and VR1-like immunoreactivity, in the central nervous system of the rat and human. Proc Natl Acad Sci U S A (2000) 97:3655-60. doi:10.1073/pnas.97.7.3655.
    • (2000) Proc Natl Acad Sci U S A , vol.97 , pp. 3655-3660
    • Mezey, E.1    Toth, Z.E.2    Cortright, D.N.3    Arzubi, M.K.4    Krause, J.E.5    Elde, R.6
  • 126
    • 0034213855 scopus 로고    scopus 로고
    • Anandamide and the question of its functional role for activation of capsaicin receptors
    • doi:10.1016/S0165-6147(00)01484-X
    • Szolcsanyi J. Anandamide and the question of its functional role for activation of capsaicin receptors. Trends Pharmacol Sci (2000) 21:203-4. doi:10.1016/S0165-6147(00)01484-X.
    • (2000) Trends Pharmacol Sci , vol.21 , pp. 203-204
    • Szolcsanyi, J.1
  • 127
    • 0034977496 scopus 로고    scopus 로고
    • The vanilloid receptor (VR1)-mediated effects of anandamide are potently enhanced by the cAMP-dependent protein kinase
    • doi:10.1046/j.1471-4159.2001.00406.x
    • De Petrocellis L, Harrison S, Bisogno T, Tognetto M, Brandi I, Smith GD, et al. The vanilloid receptor (VR1)-mediated effects of anandamide are potently enhanced by the cAMP-dependent protein kinase. J Neurochem (2001) 77:1660-3. doi:10.1046/j.1471-4159.2001.00406.x.
    • (2001) J Neurochem , vol.77 , pp. 1660-1663
    • De Petrocellis, L.1    Harrison, S.2    Bisogno, T.3    Tognetto, M.4    Brandi, I.5    Smith, G.D.6
  • 128
    • 0037062411 scopus 로고    scopus 로고
    • An endogenous capsaicin-like substance with high potency at recombinant and native vanilloid VR1 receptors
    • doi:10.1073/pnas.122196999
    • Huang SM, Bisogno T, Trevisani M, Al-Hayani A, De Petrocellis L, Fezza F, et al. An endogenous capsaicin-like substance with high potency at recombinant and native vanilloid VR1 receptors. Proc Natl Acad Sci U S A (2002) 99:8400-5. doi:10.1073/pnas.122196999.
    • (2002) Proc Natl Acad Sci U S A , vol.99 , pp. 8400-8405
    • Huang, S.M.1    Bisogno, T.2    Trevisani, M.3    Al-Hayani, A.4    De Petrocellis, L.5    Fezza, F.6
  • 129
    • 38649097877 scopus 로고    scopus 로고
    • Anandamide inhibits metabolism and physiological actions of 2-arachidonoylglycerol in the striatum
    • doi:10.1038/nn2042
    • Maccarrone M, Rossi S, Bari M, De Chiara V, Fezza F, Musella A, et al. Anandamide inhibits metabolism and physiological actions of 2-arachidonoylglycerol in the striatum. Nat Neurosci (2008) 11:152-9. doi:10.1038/nn2042.
    • (2008) Nat Neurosci , vol.11 , pp. 152-159
    • Maccarrone, M.1    Rossi, S.2    Bari, M.3    De Chiara, V.4    Fezza, F.5    Musella, A.6
  • 130
    • 0036233834 scopus 로고    scopus 로고
    • Postsynaptic endocannabinoid release is critical to long-term depression in the striatum
    • Gerdeman GL, Ronesi J, Lovinger DM. Postsynaptic endocannabinoid release is critical to long-term depression in the striatum. Nat Neurosci (2002) 5:446-51.
    • (2002) Nat Neurosci , vol.5 , pp. 446-451
    • Gerdeman, G.L.1    Ronesi, J.2    Lovinger, D.M.3
  • 131
    • 0037104758 scopus 로고    scopus 로고
    • Experimental parkinsonism alters endocannabinoid degradation: implications for striatal glutamatergic transmission
    • Gubellini P, Picconi B, Bari M, Battista N, Calabresi P, Centonze D, et al. Experimental parkinsonism alters endocannabinoid degradation: implications for striatal glutamatergic transmission. J Neurosci (2002) 22:6900-7.
    • (2002) J Neurosci , vol.22 , pp. 6900-6907
    • Gubellini, P.1    Picconi, B.2    Bari, M.3    Battista, N.4    Calabresi, P.5    Centonze, D.6
  • 132
    • 0035050883 scopus 로고    scopus 로고
    • Endogenous cannabinoids mediate retrograde signals from depolarized postsynaptic neurons to presynaptic terminals
    • doi:10.1016/S0896-6273(01)00247-1
    • Ohno-Shosaku T, Maejima T, Kano M. Endogenous cannabinoids mediate retrograde signals from depolarized postsynaptic neurons to presynaptic terminals. Neuron (2001) 29:729-38. doi:10.1016/S0896-6273(01)00247-1.
    • (2001) Neuron , vol.29 , pp. 729-738
    • Ohno-Shosaku, T.1    Maejima, T.2    Kano, M.3
  • 133
    • 0035967145 scopus 로고    scopus 로고
    • Endogenous cannabinoids mediate retrograde signalling at hippocampal synapses
    • doi:10.1038/35069076
    • Wilson RI, Nicoll RA. Endogenous cannabinoids mediate retrograde signalling at hippocampal synapses. Nature (2001) 410:588-92. doi:10.1038/35069076.
    • (2001) Nature , vol.410 , pp. 588-592
    • Wilson, R.I.1    Nicoll, R.A.2
  • 134
    • 0035888999 scopus 로고    scopus 로고
    • Cerebellar depolarization-induced suppression of inhibition is mediated by endogenous cannabinoids
    • Kreitzer AC, Regehr WG. Cerebellar depolarization-induced suppression of inhibition is mediated by endogenous cannabinoids. J Neurosci (2001) 21:RC174.
    • (2001) J Neurosci , vol.21
    • Kreitzer, A.C.1    Regehr, W.G.2
  • 135
    • 0027078685 scopus 로고
    • Isolation and structure of a brain constituent that binds to the cannabinoid receptor
    • doi:10.1126/science.1470919
    • Devane WA, Hanus L, Breuer A, Pertwee RG, Stevenson LA, Griffin G, et al. Isolation and structure of a brain constituent that binds to the cannabinoid receptor. Science (1992) 258:1946-9. doi:10.1126/science.1470919.
    • (1992) Science , vol.258 , pp. 1946-1949
    • Devane, W.A.1    Hanus, L.2    Breuer, A.3    Pertwee, R.G.4    Stevenson, L.A.5    Griffin, G.6
  • 136
    • 0028970517 scopus 로고
    • 2-Arachidonoylglycerol: a possible endogenous cannabinoid receptor ligand in brain
    • doi:10.1006/bbrc.1995.2437
    • Sugiura T, Kondo S, Sukagawa A, Nakane S, Shinoda A, Itoh K, et al. 2-Arachidonoylglycerol: a possible endogenous cannabinoid receptor ligand in brain. Biochem Biophys Res Commun (1995) 215:89-97. doi:10.1006/bbrc.1995.2437.
    • (1995) Biochem Biophys Res Commun , vol.215 , pp. 89-97
    • Sugiura, T.1    Kondo, S.2    Sukagawa, A.3    Nakane, S.4    Shinoda, A.5    Itoh, K.6
  • 137
    • 0035957425 scopus 로고    scopus 로고
    • 2-Arachidonyl glyceryl ether, an endogenous agonist of the cannabinoid CB1 receptor
    • doi:10.1073/pnas.061029898
    • Hanus L, Abu-LafiS, Fride E, Breuer A, Vogel Z, Shalev DE, et al. 2-Arachidonyl glyceryl ether, an endogenous agonist of the cannabinoid CB1 receptor. Proc Natl Acad Sci U S A (2001) 98:3662-5. doi:10.1073/pnas.061029898.
    • (2001) Proc Natl Acad Sci U S A , vol.98 , pp. 3662-3665
    • Hanus, L.1    Abu-Lafi, S.2    Fride, E.3    Breuer, A.4    Vogel, Z.5    Shalev, D.E.6
  • 138
    • 0036260823 scopus 로고    scopus 로고
    • Characterization of a novel endocannabinoid, virodhamine, with antagonist activity at the CB1 receptor
    • doi:10.1124/jpet.301.3.1020
    • Porter AC, Sauer JM, Knierman MD, Becker GW, Berna MJ, Bao J, et al. Characterization of a novel endocannabinoid, virodhamine, with antagonist activity at the CB1 receptor. J Pharmacol Exp Ther (2002) 301:1020-4. doi:10.1124/jpet.301.3.1020.
    • (2002) J Pharmacol Exp Ther , vol.301 , pp. 1020-1024
    • Porter, A.C.1    Sauer, J.M.2    Knierman, M.D.3    Becker, G.W.4    Berna, M.J.5    Bao, J.6
  • 139
    • 0035899302 scopus 로고    scopus 로고
    • Presynaptic specificity of endocannabinoid signaling in the hippocampus
    • doi:10.1016/S0896-6273(01)00372-5
    • Wilson RI, Kunos G, Nicoll RA. Presynaptic specificity of endocannabinoid signaling in the hippocampus. Neuron (2001) 31:453-62. doi:10.1016/S0896-6273(01)00372-5.
    • (2001) Neuron , vol.31 , pp. 453-462
    • Wilson, R.I.1    Kunos, G.2    Nicoll, R.A.3
  • 140
    • 34548512479 scopus 로고    scopus 로고
    • Biosynthetic pathways of the endocannabinoid anandamide
    • doi:10.1002/cbdv.200790155
    • Okamoto Y, Wang J, Morishita J, Ueda N. Biosynthetic pathways of the endocannabinoid anandamide. Chem Biodivers (2007) 4:1842-57. doi:10.1002/cbdv.200790155.
    • (2007) Chem Biodivers , vol.4 , pp. 1842-1857
    • Okamoto, Y.1    Wang, J.2    Morishita, J.3    Ueda, N.4
  • 141
    • 75949116246 scopus 로고    scopus 로고
    • The endocannabinoid 2-arachidonoylglycerol produced by diacylglycerol lipase alpha mediates retrograde suppression of synaptic transmission
    • doi:10.1016/j.neuron.2010.01.021
    • Tanimura A, Yamazaki M, Hashimotodani Y, Uchigashima M, Kawata S, Abe M, et al. The endocannabinoid 2-arachidonoylglycerol produced by diacylglycerol lipase alpha mediates retrograde suppression of synaptic transmission. Neuron (2010) 65:320-7. doi:10.1016/j.neuron.2010.01.021.
    • (2010) Neuron , vol.65 , pp. 320-327
    • Tanimura, A.1    Yamazaki, M.2    Hashimotodani, Y.3    Uchigashima, M.4    Kawata, S.5    Abe, M.6
  • 142
    • 28944431521 scopus 로고    scopus 로고
    • Endocannabinoids in the central nervous system: from neuronal networks to behavior
    • doi:10.2174/156800705774933069
    • Fride E. Endocannabinoids in the central nervous system: from neuronal networks to behavior. Curr Drug Targets CNS Neurol Disord (2005) 4:633-42. doi:10.2174/156800705774933069.
    • (2005) Curr Drug Targets CNS Neurol Disord , vol.4 , pp. 633-642
    • Fride, E.1
  • 143
    • 0033998951 scopus 로고    scopus 로고
    • Biochemistry and pharmacology of the endocannabinoids arachidonylethanolamide and 2-arachidonylglycerol
    • doi:10.1016/S0090-6980(00)00051-4
    • Hillard CJ. Biochemistry and pharmacology of the endocannabinoids arachidonylethanolamide and 2-arachidonylglycerol. Prostaglandins Other Lipid Mediat (2000) 61:3-18. doi:10.1016/S0090-6980(00)00051-4.
    • (2000) Prostaglandins Other Lipid Mediat , vol.61 , pp. 3-18
    • Hillard, C.J.1
  • 144
    • 0029904838 scopus 로고    scopus 로고
    • Molecular characterization of an enzyme that degrades neuromodulatory fatty-acid amides
    • doi:10.1038/384083a0
    • Cravatt BF, Giang DK, Mayfield SP, Boger DL, Lerner RA, Gilula NB. Molecular characterization of an enzyme that degrades neuromodulatory fatty-acid amides. Nature (1996) 384:83-7. doi:10.1038/384083a0.
    • (1996) Nature , vol.384 , pp. 83-87
    • Cravatt, B.F.1    Giang, D.K.2    Mayfield, S.P.3    Boger, D.L.4    Lerner, R.A.5    Gilula, N.B.6
  • 145
    • 43749096323 scopus 로고    scopus 로고
    • Activation of the endocannabinoid system by organophosphorus nerve agents
    • doi:10.1038/nchembio.86
    • Nomura DK, Blankman JL, Simon GM, Fujioka K, Issa RS, Ward AM, et al. Activation of the endocannabinoid system by organophosphorus nerve agents. Nat Chem Biol (2008) 4:373-8. doi:10.1038/nchembio.86.
    • (2008) Nat Chem Biol , vol.4 , pp. 373-378
    • Nomura, D.K.1    Blankman, J.L.2    Simon, G.M.3    Fujioka, K.4    Issa, R.S.5    Ward, A.M.6
  • 146
    • 37149013708 scopus 로고    scopus 로고
    • A comprehensive profile of brain enzymes that hydrolyze the endocannabinoid 2-arachidonoylglycerol
    • doi:10.1016/j.chembiol.2007.11.006
    • Blankman JL, Simon GM, Cravatt BF. A comprehensive profile of brain enzymes that hydrolyze the endocannabinoid 2-arachidonoylglycerol. Chem Biol (2007) 14:1347-56. doi:10.1016/j.chembiol.2007.11.006.
    • (2007) Chem Biol , vol.14 , pp. 1347-1356
    • Blankman, J.L.1    Simon, G.M.2    Cravatt, B.F.3
  • 147
    • 77955053537 scopus 로고    scopus 로고
    • The serine hydrolase ABHD6 controls the accumulation and efficacy of 2-AG at cannabinoid receptors
    • doi:10.1038/nn.2601
    • Marrs WR, Blankman JL, Horne EA, Thomazeau A, Lin YH, Coy J, et al. The serine hydrolase ABHD6 controls the accumulation and efficacy of 2-AG at cannabinoid receptors. Nat Neurosci (2010) 13:951-7. doi:10.1038/nn.2601.
    • (2010) Nat Neurosci , vol.13 , pp. 951-957
    • Marrs, W.R.1    Blankman, J.L.2    Horne, E.A.3    Thomazeau, A.4    Lin, Y.H.5    Coy, J.6
  • 148
    • 22244484464 scopus 로고    scopus 로고
    • Structure and function of fatty acid amide hydrolase
    • doi:10.1146/annurev.biochem.74.082803.133450
    • McKinney MK, Cravatt BF. Structure and function of fatty acid amide hydrolase. Annu Rev Biochem (2005) 74:411-32. doi:10.1146/annurev.biochem.74.082803.133450.
    • (2005) Annu Rev Biochem , vol.74 , pp. 411-432
    • McKinney, M.K.1    Cravatt, B.F.2
  • 149
    • 15744385109 scopus 로고    scopus 로고
    • Characterization of the fatty acid amide hydrolase inhibitor cyclohexyl carbamic acid 3-carbamoyl-biphenyl-3-yl ester (URB597): effects on anandamide and oleoylethanolamide deactivation
    • doi:10.1124/jpet.104.078980
    • Fegley D, Gaetani S, Duranti A, Tontini A, Mor M, Tarzia G, et al. Characterization of the fatty acid amide hydrolase inhibitor cyclohexyl carbamic acid 3-carbamoyl-biphenyl-3-yl ester (URB597): effects on anandamide and oleoylethanolamide deactivation. J Pharmacol Exp Ther (2005) 313:352-8. doi:10.1124/jpet.104.078980.
    • (2005) J Pharmacol Exp Ther , vol.313 , pp. 352-358
    • Fegley, D.1    Gaetani, S.2    Duranti, A.3    Tontini, A.4    Mor, M.5    Tarzia, G.6
  • 150
    • 73149104901 scopus 로고    scopus 로고
    • Monoacylglycerol lipase limits the duration of endocannabinoid-mediated depolarization-induced suppression of excitation in autaptic hippocampal neurons
    • doi:10.1124/mol.109.059030
    • Straiker A, Hu SS, Long JZ, Arnold A, Wager-Miller J, Cravatt BF, et al. Monoacylglycerol lipase limits the duration of endocannabinoid-mediated depolarization-induced suppression of excitation in autaptic hippocampal neurons. Mol Pharmacol (2009) 76:1220-7. doi:10.1124/mol.109.059030.
    • (2009) Mol Pharmacol , vol.76 , pp. 1220-1227
    • Straiker, A.1    Hu, S.S.2    Long, J.Z.3    Arnold, A.4    Wager-Miller, J.5    Cravatt, B.F.6
  • 151
    • 64749114255 scopus 로고    scopus 로고
    • Discovery and characterization of a highly selective FAAH inhibitor that reduces inflammatory pain
    • doi:10.1016/j.chembiol.2009.02.013
    • Ahn K, Johnson DS, Mileni M, Beidler D, Long JZ, McKinney MK, et al. Discovery and characterization of a highly selective FAAH inhibitor that reduces inflammatory pain. Chem Biol (2009) 16:411-20. doi:10.1016/j.chembiol.2009.02.013.
    • (2009) Chem Biol , vol.16 , pp. 411-420
    • Ahn, K.1    Johnson, D.S.2    Mileni, M.3    Beidler, D.4    Long, J.Z.5    McKinney, M.K.6
  • 152
    • 33746474287 scopus 로고    scopus 로고
    • Pharmacological profile of the selective FAAH inhibitor KDS-4103 (URB597)
    • doi:10.1111/j.1527-3458.2006.00021.x
    • Piomelli D, Tarzia G, Duranti A, Tontini A, Mor M, Compton TR, et al. Pharmacological profile of the selective FAAH inhibitor KDS-4103 (URB597). CNS Drug Rev (2006) 12:21-38. doi:10.1111/j.1527-3458.2006.00021.x.
    • (2006) CNS Drug Rev , vol.12 , pp. 21-38
    • Piomelli, D.1    Tarzia, G.2    Duranti, A.3    Tontini, A.4    Mor, M.5    Compton, T.R.6
  • 153
    • 78650619344 scopus 로고    scopus 로고
    • Inhibition of endocannabinoid catabolic enzymes elicits anxiolytic-like effects in the marble burying assay
    • doi:10.1016/j.pbb.2010.12.002
    • Kinsey SG, O'Neal ST, Long JZ, Cravatt BF, Lichtman AH. Inhibition of endocannabinoid catabolic enzymes elicits anxiolytic-like effects in the marble burying assay. Pharmacol Biochem Behav (2011) 98:21-7. doi:10.1016/j.pbb.2010.12.002.
    • (2011) Pharmacol Biochem Behav , vol.98 , pp. 21-27
    • Kinsey, S.G.1    O'Neal, S.T.2    Long, J.Z.3    Cravatt, B.F.4    Lichtman, A.H.5
  • 154
    • 77953775181 scopus 로고    scopus 로고
    • Regulation of inflammatory pain by inhibition of fatty acid amide hydrolase
    • doi:10.1124/jpet.109.164806
    • Naidu PS, Kinsey SG, Guo TL, Cravatt BF, Lichtman AH. Regulation of inflammatory pain by inhibition of fatty acid amide hydrolase. J Pharmacol Exp Ther (2010) 334:182-90. doi:10.1124/jpet.109.164806.
    • (2010) J Pharmacol Exp Ther , vol.334 , pp. 182-190
    • Naidu, P.S.1    Kinsey, S.G.2    Guo, T.L.3    Cravatt, B.F.4    Lichtman, A.H.5
  • 155
    • 73949109254 scopus 로고    scopus 로고
    • Dual blockade of FAAH and MAGL identifies behavioral processes regulated by endocannabinoid crosstalk in vivo
    • doi:10.1073/pnas.0909411106
    • Long JZ, Nomura DK, Vann RE, Walentiny DM, Booker L, Jin X, et al. Dual blockade of FAAH and MAGL identifies behavioral processes regulated by endocannabinoid crosstalk in vivo. Proc Natl Acad Sci U S A (2009) 106:20270-5. doi:10.1073/pnas.0909411106.
    • (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 20270-5
    • Long, J.Z.1    Nomura, D.K.2    Vann, R.E.3    Walentiny, D.M.4    Booker, L.5    Jin, X.6
  • 156
    • 77956181836 scopus 로고    scopus 로고
    • Chronic monoacylglycerol lipase blockade causes functional antagonism of the endocannabinoid system
    • doi:10.1038/nn.2616
    • Schlosburg JE, Blankman JL, Long JZ, Nomura DK, Pan B, Kinsey SG, et al. Chronic monoacylglycerol lipase blockade causes functional antagonism of the endocannabinoid system. Nat Neurosci (2010) 13:1113-9. doi:10.1038/nn.2616.
    • (2010) Nat Neurosci , vol.13 , pp. 1113-1119
    • Schlosburg, J.E.1    Blankman, J.L.2    Long, J.Z.3    Nomura, D.K.4    Pan, B.5    Kinsey, S.G.6
  • 157
    • 78649924956 scopus 로고    scopus 로고
    • Monoacylglycerol lipase activity is a critical modulator of the tone and integrity of the endocannabinoid system
    • doi:10.1124/mol.110.068304
    • Chanda PK, Gao Y, Mark L, Btesh J, Strassle BW, Lu P, et al. Monoacylglycerol lipase activity is a critical modulator of the tone and integrity of the endocannabinoid system. Mol Pharmacol (2010) 78:996-1003. doi:10.1124/mol.110.068304.
    • (2010) Mol Pharmacol , vol.78 , pp. 996-1003
    • Chanda, P.K.1    Gao, Y.2    Mark, L.3    Btesh, J.4    Strassle, B.W.5    Lu, P.6
  • 158
    • 80053024234 scopus 로고    scopus 로고
    • Alterations of endocannabinoid signaling, synaptic plasticity, learning, and memory in monoacylglycerol lipase knock-out mice
    • doi:10.1523/JNEUROSCI.2075-11.2011
    • Pan B, Wang W, Zhong P, Blankman JL, Cravatt BF, Liu QS. Alterations of endocannabinoid signaling, synaptic plasticity, learning, and memory in monoacylglycerol lipase knock-out mice. J Neurosci (2011) 31:13420-30. doi:10.1523/JNEUROSCI.2075-11.2011.
    • (2011) J Neurosci , vol.31 , pp. 13420-30
    • Pan, B.1    Wang, W.2    Zhong, P.3    Blankman, J.L.4    Cravatt, B.F.5    Liu, Q.S.6
  • 159
    • 0034087404 scopus 로고    scopus 로고
    • Marijuana and medicine: assessing the science base: a summary of the 1999 Institute of Medicine report
    • doi:10.1001/archpsyc.57.6.547
    • Watson SJ, Benson JA Jr, Joy JE. Marijuana and medicine: assessing the science base: a summary of the 1999 Institute of Medicine report. Arch Gen Psychiatry (2000) 57:547-52. doi:10.1001/archpsyc.57.6.547.
    • (2000) Arch Gen Psychiatry , vol.57 , pp. 547-552
    • Watson, S.J.1    Benson Jr., J.A.2    Joy, J.E.3
  • 160
    • 33645821022 scopus 로고    scopus 로고
    • Cannabidiol, a Cannabis sativa constituent, as an antipsychotic drug
    • doi:10.1590/S0100-879X2006000400001
    • Zuardi AW, Crippa JA, Hallak JE, Moreira FA, Guimaraes FS. Cannabidiol, a Cannabis sativa constituent, as an antipsychotic drug. Braz J Med Biol Res (2006) 39:421-9. doi:10.1590/S0100-879X2006000400001.
    • (2006) Braz J Med Biol Res , vol.39 , pp. 421-429
    • Zuardi, A.W.1    Crippa, J.A.2    Hallak, J.E.3    Moreira, F.A.4    Guimaraes, F.S.5
  • 161
    • 0036399623 scopus 로고    scopus 로고
    • Cognitive and subjective dose-response effects of acute oral Delta 9-tetrahydrocannabinol (THC) in infrequent cannabis users
    • doi:10.1007/s00213-002-1169-0
    • Curran HV, Brignell C, Fletcher S, Middleton P, Henry J. Cognitive and subjective dose-response effects of acute oral Delta 9-tetrahydrocannabinol (THC) in infrequent cannabis users. Psychopharmacology (Berl) (2002) 164:61-70. doi:10.1007/s00213-002-1169-0.
    • (2002) Psychopharmacology (Berl) , vol.164 , pp. 61-70
    • Curran, H.V.1    Brignell, C.2    Fletcher, S.3    Middleton, P.4    Henry, J.5
  • 162
    • 0035077403 scopus 로고    scopus 로고
    • A literature review of the consequences of prenatal marihuana exposure. An emerging theme of a deficiency in aspects of executive function
    • doi:10.1016/S0892-0362(00)00119-7
    • Fried PA, Smith AM. A literature review of the consequences of prenatal marihuana exposure. An emerging theme of a deficiency in aspects of executive function. Neurotoxicol Teratol (2001) 23:1-11. doi:10.1016/S0892-0362(00)00119-7.
    • (2001) Neurotoxicol Teratol , vol.23 , pp. 1-11
    • Fried, P.A.1    Smith, A.M.2
  • 163
    • 0037164390 scopus 로고    scopus 로고
    • Cannabis use in adolescence and risk for adult psychosis: longitudinal prospective study
    • doi:10.1136/bmj.325.7374.1212
    • Arseneault L, Cannon M, Poulton R, Murray R, Caspi A, Moffitt TE. Cannabis use in adolescence and risk for adult psychosis: longitudinal prospective study. BMJ (2002) 325:1212-3. doi:10.1136/bmj.325.7374.1212.
    • (2002) BMJ , vol.325 , pp. 1212-1213
    • Arseneault, L.1    Cannon, M.2    Poulton, R.3    Murray, R.4    Caspi, A.5    Moffitt, T.E.6
  • 164
    • 0037460202 scopus 로고    scopus 로고
    • Does marijuana use cause the use of other drugs?
    • doi:10.1001/jama.289.4.482
    • Kandel DB. Does marijuana use cause the use of other drugs? JAMA (2003) 289:482-3. doi:10.1001/jama.289.4.482.
    • (2003) JAMA , vol.289 , pp. 482-483
    • Kandel, D.B.1
  • 165
    • 28844445679 scopus 로고    scopus 로고
    • Maternal smoking, drinking or cannabis use during pregnancy and neurobehavioral and cognitive functioning in human offspring
    • doi:10.1016/j.neubiorev.2005.04.005
    • Huizink AC, Mulder EJ. Maternal smoking, drinking or cannabis use during pregnancy and neurobehavioral and cognitive functioning in human offspring. Neurosci Biobehav Rev (2006) 30:24-41. doi:10.1016/j.neubiorev.2005.04.005.
    • (2006) Neurosci Biobehav Rev , vol.30 , pp. 24-41
    • Huizink, A.C.1    Mulder, E.J.2
  • 166
    • 3242789385 scopus 로고    scopus 로고
    • The psychotomimetic effects of intravenous delta-9-tetrahydrocannabinol in healthy individuals: implications for psychosis
    • doi:10.1038/sj.npp.1300496
    • D'Souza DC, Perry E, Macdougall L, Ammerman Y, Cooper T, Wu YT, et al. The psychotomimetic effects of intravenous delta-9-tetrahydrocannabinol in healthy individuals: implications for psychosis. Neuropsychopharmacology (2004) 29:1558-72. doi:10.1038/sj.npp.1300496.
    • (2004) Neuropsychopharmacology , vol.29 , pp. 1558-1572
    • D'Souza, D.C.1    Perry, E.2    Macdougall, L.3    Ammerman, Y.4    Cooper, T.5    Wu, Y.T.6
  • 167
    • 44549087417 scopus 로고    scopus 로고
    • Blunted psychotomimetic and amnestic effects of delta-9-tetrahydrocannabinol in frequent users of cannabis
    • doi:10.1038/sj.npp.1301643
    • D'Souza DC, Ranganathan M, Braley G, Gueorguieva R, Zimolo Z, Cooper T, et al. Blunted psychotomimetic and amnestic effects of delta-9-tetrahydrocannabinol in frequent users of cannabis. Neuropsychopharmacology (2008) 33:2505-16. doi:10.1038/sj.npp.1301643.
    • (2008) Neuropsychopharmacology , vol.33 , pp. 2505-2516
    • D'Souza, D.C.1    Ranganathan, M.2    Braley, G.3    Gueorguieva, R.4    Zimolo, Z.5    Cooper, T.6
  • 168
    • 0026592569 scopus 로고
    • Pharmacological profile of a series of bicyclic cannabinoid analogs: classification as cannabimimetic agents
    • Compton DR, Johnson MR, Melvin LS, Martin BR. Pharmacological profile of a series of bicyclic cannabinoid analogs: classification as cannabimimetic agents. J Pharmacol Exp Ther (1992) 260:201-9.
    • (1992) J Pharmacol Exp Ther , vol.260 , pp. 201-209
    • Compton, D.R.1    Johnson, M.R.2    Melvin, L.S.3    Martin, B.R.4
  • 169
    • 0034520712 scopus 로고    scopus 로고
    • Cannabinoids in clinical practice
    • doi:10.2165/00003495-200060060-00005
    • Williamson EM, Evans FJ. Cannabinoids in clinical practice. Drugs (2000) 60:1303-14. doi:10.2165/00003495-200060060-00005.
    • (2000) Drugs , vol.60 , pp. 1303-1314
    • Williamson, E.M.1    Evans, F.J.2
  • 170
    • 0028089295 scopus 로고
    • Anxiolytic effect of cannabidiol derivatives in the elevated plus-maze
    • doi:10.1016/0306-3623(94)90027-2
    • Guimaraes FS, De Aguiar JC, Mechoulam R, Breuer A. Anxiolytic effect of cannabidiol derivatives in the elevated plus-maze. Gen Pharmacol (1994) 25:161-4. doi:10.1016/0306-3623(94)90027-2.
    • (1994) Gen Pharmacol , vol.25 , pp. 161-164
    • Guimaraes, F.S.1    De Aguiar, J.C.2    Mechoulam, R.3    Breuer, A.4
  • 171
    • 27644440716 scopus 로고    scopus 로고
    • Agonistic properties of cannabidiol at 5-HT1a receptors
    • doi:10.1007/s11064-005-6978-1
    • Russo EB, Burnett A, Hall B, Parker KK. Agonistic properties of cannabidiol at 5-HT1a receptors. Neurochem Res (2005) 30:1037-43. doi:10.1007/s11064-005-6978-1.
    • (2005) Neurochem Res , vol.30 , pp. 1037-1043
    • Russo, E.B.1    Burnett, A.2    Hall, B.3    Parker, K.K.4
  • 172
    • 33750292887 scopus 로고    scopus 로고
    • Anxiolytic-like effect of cannabidiol in the rat Vogel conflict test
    • doi:10.1016/j.pnpbp.2006.06.004
    • Moreira FA, Aguiar DC, Guimaraes FS. Anxiolytic-like effect of cannabidiol in the rat Vogel conflict test. Prog Neuropsychopharmacol Biol Psychiatry (2006) 30:1466-71. doi:10.1016/j.pnpbp.2006.06.004.
    • (2006) Prog Neuropsychopharmacol Biol Psychiatry , vol.30 , pp. 1466-1471
    • Moreira, F.A.1    Aguiar, D.C.2    Guimaraes, F.S.3
  • 173
    • 34248160496 scopus 로고    scopus 로고
    • Dorsolateral prefrontal cortex N-acetylaspartate/total creatine (NAA/tCr) loss in male recreational cannabis users
    • doi:10.1016/j.biopsych.2006.08.027
    • Hermann D, Sartorius A, Welzel H, Walter S, Skopp G, Ende G, et al. Dorsolateral prefrontal cortex N-acetylaspartate/total creatine (NAA/tCr) loss in male recreational cannabis users. Biol Psychiatry (2007) 61:1281-9. doi:10.1016/j.biopsych.2006.08.027.
    • (2007) Biol Psychiatry , vol.61 , pp. 1281-1289
    • Hermann, D.1    Sartorius, A.2    Welzel, H.3    Walter, S.4    Skopp, G.5    Ende, G.6
  • 174
    • 77952551436 scopus 로고    scopus 로고
    • Antidepressant-like effect of delta9-tetrahydrocannabinol and other cannabinoids isolated from Cannabis sativa L
    • doi:10.1016/j.pbb.2010.03.004
    • El-Alfy AT, Ivey K, Robinson K, Ahmed S, Radwan M, Slade D, et al. Antidepressant-like effect of delta9-tetrahydrocannabinol and other cannabinoids isolated from Cannabis sativa L. Pharmacol Biochem Behav (2010) 95:434-42. doi:10.1016/j.pbb.2010.03.004.
    • (2010) Pharmacol Biochem Behav , vol.95 , pp. 434-442
    • El-Alfy, A.T.1    Ivey, K.2    Robinson, K.3    Ahmed, S.4    Radwan, M.5    Slade, D.6
  • 175
    • 77957228353 scopus 로고    scopus 로고
    • A behavioural comparison of acute and chronic Delta9-tetrahydrocannabinol and cannabidiol in C57BL/6JArc mice
    • doi:10.1017/S1461145709990605
    • Long LE, Chesworth R, Huang XF, McGregor IS, Arnold JC, Karl T. A behavioural comparison of acute and chronic Delta9-tetrahydrocannabinol and cannabidiol in C57BL/6JArc mice. Int J Neuropsychopharmacol (2010) 13:861-76. doi:10.1017/S1461145709990605.
    • (2010) Int J Neuropsychopharmacol , vol.13 , pp. 861-876
    • Long, L.E.1    Chesworth, R.2    Huang, X.F.3    McGregor, I.S.4    Arnold, J.C.5    Karl, T.6
  • 176
    • 74549165354 scopus 로고    scopus 로고
    • Antidepressant-like effects of cannabidiol in mice: possible involvement of 5-HT1A receptors
    • doi:10.1111/j.1476-5381.2009.00521.x
    • Zanelati TV, Biojone C, Moreira FA, Guimaraes FS, Joca SR. Antidepressant-like effects of cannabidiol in mice: possible involvement of 5-HT1A receptors. Br J Pharmacol (2010) 159:122-8. doi:10.1111/j.1476-5381.2009.00521.x.
    • (2010) Br J Pharmacol , vol.159 , pp. 122-128
    • Zanelati, T.V.1    Biojone, C.2    Moreira, F.A.3    Guimaraes, F.S.4    Joca, S.R.5
  • 177
    • 33847653702 scopus 로고    scopus 로고
    • Cannabidiol displays unexpectedly high potency as an antagonist of CB1 and CB2 receptor agonists in vitro
    • doi:10.1038/sj.bjp.0707133
    • Thomas A, Baillie GL, Phillips AM, Razdan RK, Ross RA, Pertwee RG. Cannabidiol displays unexpectedly high potency as an antagonist of CB1 and CB2 receptor agonists in vitro. Br J Pharmacol (2007) 150:613-23. doi:10.1038/sj.bjp.0707133.
    • (2007) Br J Pharmacol , vol.150 , pp. 613-623
    • Thomas, A.1    Baillie, G.L.2    Phillips, A.M.3    Razdan, R.K.4    Ross, R.A.5    Pertwee, R.G.6
  • 178
    • 38349158960 scopus 로고    scopus 로고
    • The diverse CB1 and CB2 receptor pharmacology of three plant cannabinoids: delta9-tetrahydrocannabinol, cannabidiol and delta9-tetrahydrocannabivarin
    • doi:10.1038/sj.bjp.0707442
    • Pertwee RG. The diverse CB1 and CB2 receptor pharmacology of three plant cannabinoids: delta9-tetrahydrocannabinol, cannabidiol and delta9-tetrahydrocannabivarin. Br J Pharmacol (2008) 153:199-215. doi:10.1038/sj.bjp.0707442.
    • (2008) Br J Pharmacol , vol.153 , pp. 199-215
    • Pertwee, R.G.1
  • 179
    • 46749129338 scopus 로고    scopus 로고
    • TRPV2 is activated by cannabidiol and mediates CGRP release in cultured rat dorsal root ganglion neurons
    • doi:10.1523/JNEUROSCI.0504-08.2008
    • Qin N, Neeper MP, Liu Y, Hutchinson TL, Lubin ML, Flores CM. TRPV2 is activated by cannabidiol and mediates CGRP release in cultured rat dorsal root ganglion neurons. J Neurosci (2008) 28:6231-8. doi:10.1523/JNEUROSCI.0504-08.2008.
    • (2008) J Neurosci , vol.28 , pp. 6231-6238
    • Qin, N.1    Neeper, M.P.2    Liu, Y.3    Hutchinson, T.L.4    Lubin, M.L.5    Flores, C.M.6
  • 180
    • 0034751335 scopus 로고    scopus 로고
    • Molecular targets for cannabidiol and its synthetic analogues: effect on vanilloid VR1 receptors and on the cellular uptake and enzymatic hydrolysis of anandamide
    • doi:10.1038/sj.bjp.0704327
    • Bisogno T, Hanus L, De Petrocellis L, Tchilibon S, Ponde DE, Brandi I, et al. Molecular targets for cannabidiol and its synthetic analogues: effect on vanilloid VR1 receptors and on the cellular uptake and enzymatic hydrolysis of anandamide. Br J Pharmacol (2001) 134:845-52. doi:10.1038/sj.bjp.0704327.
    • (2001) Br J Pharmacol , vol.134 , pp. 845-852
    • Bisogno, T.1    Hanus, L.2    De Petrocellis, L.3    Tchilibon, S.4    Ponde, D.E.5    Brandi, I.6
  • 181
    • 79952535110 scopus 로고    scopus 로고
    • Cannabinoids inhibit the synaptic uptake of adenosine and dopamine in the rat and mouse striatum
    • doi:10.1016/j.ejphar.2011.01.013
    • Pandolfo P, Silveirinha V, Dos Santos-Rodrigues A, Venance L, Ledent C, Takahashi RN, et al. Cannabinoids inhibit the synaptic uptake of adenosine and dopamine in the rat and mouse striatum. Eur J Pharmacol (2011) 655:38-45. doi:10.1016/j.ejphar.2011.01.013.
    • (2011) Eur J Pharmacol , vol.655 , pp. 38-45
    • Pandolfo, P.1    Silveirinha, V.2    Dos Santos-Rodrigues, A.3    Venance, L.4    Ledent, C.5    Takahashi, R.N.6
  • 182
    • 79952438369 scopus 로고    scopus 로고
    • Effects on sleep and dopamine levels of microdialysis perfusion of cannabidiol into the lateral hypothalamus of rats
    • doi:10.1016/j.lfs.2011.01.013
    • Murillo-Rodriguez E, Palomero-Rivero M, Millan-Aldaco D, Mechoulam R, Drucker-Colin R. Effects on sleep and dopamine levels of microdialysis perfusion of cannabidiol into the lateral hypothalamus of rats. Life Sci (2011) 88:504-11. doi:10.1016/j.lfs.2011.01.013.
    • (2011) Life Sci , vol.88 , pp. 504-511
    • Murillo-Rodriguez, E.1    Palomero-Rivero, M.2    Millan-Aldaco, D.3    Mechoulam, R.4    Drucker-Colin, R.5
  • 183
    • 33644540495 scopus 로고    scopus 로고
    • Cannabidiol is an allosteric modulator at mu- and delta-opioid receptors
    • doi:10.1007/s00210-006-0033-x
    • Kathmann M, Flau K, Redmer A, Trankle C, Schlicker E. Cannabidiol is an allosteric modulator at mu- and delta-opioid receptors. Naunyn Schmiedebergs Arch Pharmacol (2006) 372:354-61. doi:10.1007/s00210-006-0033-x.
    • (2006) Naunyn Schmiedebergs Arch Pharmacol , vol.372 , pp. 354-361
    • Kathmann, M.1    Flau, K.2    Redmer, A.3    Trankle, C.4    Schlicker, E.5
  • 184
    • 33646734889 scopus 로고    scopus 로고
    • Inhibition of an equilibrative nucleoside transporter by cannabidiol: a mechanism of cannabinoid immunosuppression
    • doi:10.1073/pnas.0511232103
    • Carrier EJ, Auchampach JA, Hillard CJ. Inhibition of an equilibrative nucleoside transporter by cannabidiol: a mechanism of cannabinoid immunosuppression. Proc Natl Acad Sci U S A (2006) 103:7895-900. doi:10.1073/pnas.0511232103.
    • (2006) Proc Natl Acad Sci U S A , vol.103 , pp. 7895-7900
    • Carrier, E.J.1    Auchampach, J.A.2    Hillard, C.J.3
  • 185
    • 0035112869 scopus 로고    scopus 로고
    • Ultrastructural localization of the CB1 cannabinoid receptor in mu-opioid receptor patches of the rat Caudate putamen nucleus
    • Rodriguez JJ, Mackie K, Pickel VM. Ultrastructural localization of the CB1 cannabinoid receptor in mu-opioid receptor patches of the rat Caudate putamen nucleus. J Neurosci (2001) 21:823-33.
    • (2001) J Neurosci , vol.21 , pp. 823-833
    • Rodriguez, J.J.1    Mackie, K.2    Pickel, V.M.3
  • 186
    • 33748160553 scopus 로고    scopus 로고
    • Interactions between CB1 cannabinoid and mu opioid receptors mediating inhibition of neurotransmitter release in rat nucleus accumbens core
    • doi:10.1016/j.neuropharm.2006.05.019
    • Schoffelmeer AN, Hogenboom F, Wardeh G, De Vries TJ. Interactions between CB1 cannabinoid and mu opioid receptors mediating inhibition of neurotransmitter release in rat nucleus accumbens core. Neuropharmacology (2006) 51:773-81. doi:10.1016/j.neuropharm.2006.05.019.
    • (2006) Neuropharmacology , vol.51 , pp. 773-781
    • Schoffelmeer, A.N.1    Hogenboom, F.2    Wardeh, G.3    De Vries, T.J.4
  • 187
    • 0032493197 scopus 로고    scopus 로고
    • Cannabidiol and (-)Delta 9-tetrahydrocannabinol are neuroprotective antioxidants
    • doi:10.1073/pnas.95.14.8268
    • Hampson AJ, Grimaldi M, Axelrod J, Wink D. Cannabidiol and (-)Delta 9-tetrahydrocannabinol are neuroprotective antioxidants. Proc Natl Acad Sci U S A (1998) 95:8268-73. doi:10.1073/pnas.95.14.8268.
    • (1998) Proc Natl Acad Sci U S A , vol.95 , pp. 8268-8273
    • Hampson, A.J.1    Grimaldi, M.2    Axelrod, J.3    Wink, D.4
  • 188
    • 78650961973 scopus 로고    scopus 로고
    • The interplay of cannabinoid and NMDA glutamate receptor systems in humans: preliminary evidence of interactive effects of cannabidiol and ketamine in healthy human subjects
    • doi:10.1016/j.pnpbp.2010.11.002
    • Hallak JE, Dursun SM, Bosi DC, De Macedo LR, Machado-De-Sousa JP, Abrao J, et al. The interplay of cannabinoid and NMDA glutamate receptor systems in humans: preliminary evidence of interactive effects of cannabidiol and ketamine in healthy human subjects. Prog Neuropsychopharmacol Biol Psychiatry (2011) 35:198-202. doi:10.1016/j.pnpbp.2010.11.002.
    • (2011) Prog Neuropsychopharmacol Biol Psychiatry , vol.35 , pp. 198-202
    • Hallak, J.E.1    Dursun, S.M.2    Bosi, D.C.3    De Macedo, L.R.4    Machado-De-Sousa, J.P.5    Abrao, J.6
  • 189
    • 46649094780 scopus 로고    scopus 로고
    • Involvement of 5HT1A receptors in the anxiolytic-like effects of cannabidiol injected into the dorsolateral periaqueductal gray of rats
    • doi:10.1007/s00213-008-1168-x
    • Campos AC, Guimaraes FS. Involvement of 5HT1A receptors in the anxiolytic-like effects of cannabidiol injected into the dorsolateral periaqueductal gray of rats. Psychopharmacology (Berl) (2008) 199:223-30. doi:10.1007/s00213-008-1168-x.
    • (2008) Psychopharmacology (Berl) , vol.199 , pp. 223-230
    • Campos, A.C.1    Guimaraes, F.S.2
  • 190
    • 77954145403 scopus 로고    scopus 로고
    • Cannabidiol injected into the bed nucleus of the stria terminalis modulates baroreflex activity through 5-HT1A receptors
    • doi:10.1016/j.phrs.2010.05.003
    • Alves FH, Crestani CC, Gomes FV, Guimaraes FS, Correa FM, Resstel LB. Cannabidiol injected into the bed nucleus of the stria terminalis modulates baroreflex activity through 5-HT1A receptors. Pharmacol Res (2010) 62:228-36. doi:10.1016/j.phrs.2010.05.003.
    • (2010) Pharmacol Res , vol.62 , pp. 228-236
    • Alves, F.H.1    Crestani, C.C.2    Gomes, F.V.3    Guimaraes, F.S.4    Correa, F.M.5    Resstel, L.B.6
  • 191
    • 77249134168 scopus 로고    scopus 로고
    • Cannabidiol ameliorates cognitive and motor impairments in bile-duct ligated mice via 5-HT1A receptor activation
    • doi:10.1111/j.1476-5381.2009.00589.x
    • Magen I, Avraham Y, Ackerman Z, Vorobiev L, Mechoulam R, Berry EM. Cannabidiol ameliorates cognitive and motor impairments in bile-duct ligated mice via 5-HT1A receptor activation. Br J Pharmacol (2010) 159:950-7. doi:10.1111/j.1476-5381.2009.00589.x.
    • (2010) Br J Pharmacol , vol.159 , pp. 950-957
    • Magen, I.1    Avraham, Y.2    Ackerman, Z.3    Vorobiev, L.4    Mechoulam, R.5    Berry, E.M.6
  • 192
    • 77953917373 scopus 로고    scopus 로고
    • Intra-dorsal periaqueductal gray administration of cannabidiol blocks panic-like response by activating 5-HT1A receptors
    • doi:10.1016/j.bbr.2010.05.004
    • Soares Vde P, Campos AC, Bortoli VC, Zangrossi H Jr, Guimaraes FS, Zuardi AW. Intra-dorsal periaqueductal gray administration of cannabidiol blocks panic-like response by activating 5-HT1A receptors. Behav Brain Res (2010) 213:225-9. doi:10.1016/j.bbr.2010.05.004.
    • (2010) Behav Brain Res , vol.213 , pp. 225-229
    • Soares Vde, P.1    Campos, A.C.2    Bortoli, V.C.3    Zangrossi Jr., H.4    Guimaraes, F.S.5    Zuardi, A.W.6
  • 193
    • 84856432211 scopus 로고    scopus 로고
    • Cannabidiol injected into the bed nucleus of the stria terminalis reduces the expression of contextual fear conditioning via 5-HT1A receptors
    • doi:10.1177/0269881110389095
    • Gomes FV, Reis DG, Alves FH, Correa FM, Guimaraes FS, Resstel LB. Cannabidiol injected into the bed nucleus of the stria terminalis reduces the expression of contextual fear conditioning via 5-HT1A receptors. J Psychopharmacol (2012) 26:104-13. doi:10.1177/0269881110389095.
    • (2012) J Psychopharmacol , vol.26 , pp. 104-113
    • Gomes, F.V.1    Reis, D.G.2    Alves, F.H.3    Correa, F.M.4    Guimaraes, F.S.5    Resstel, L.B.6
  • 195
    • 80051799165 scopus 로고    scopus 로고
    • Effects of intracisternal administration of cannabidiol on the cardiovascular and behavioral responses to acute restraint stress
    • doi:10.1016/j.pbb.2011.06.027
    • Granjeiro EM, Gomes FV, Guimaraes FS, Correa FM, Resstel LB. Effects of intracisternal administration of cannabidiol on the cardiovascular and behavioral responses to acute restraint stress. Pharmacol Biochem Behav (2011) 99:743-8. doi:10.1016/j.pbb.2011.06.027.
    • (2011) Pharmacol Biochem Behav , vol.99 , pp. 743-748
    • Granjeiro, E.M.1    Gomes, F.V.2    Guimaraes, F.S.3    Correa, F.M.4    Resstel, L.B.5
  • 196
    • 58149520644 scopus 로고    scopus 로고
    • Distinct effects of {delta}9-tetrahydrocannabinol and cannabidiol on neural activation during emotional processing
    • doi:10.1001/archgenpsychiatry.2008.519
    • Fusar-Poli P, Crippa JA, Bhattacharyya S, Borgwardt SJ, Allen P, Martin-Santos R, et al. Distinct effects of {delta}9-tetrahydrocannabinol and cannabidiol on neural activation during emotional processing. Arch Gen Psychiatry (2009) 66:95-105. doi:10.1001/archgenpsychiatry.2008.519.
    • (2009) Arch Gen Psychiatry , vol.66 , pp. 95-105
    • Fusar-Poli, P.1    Crippa, J.A.2    Bhattacharyya, S.3    Borgwardt, S.J.4    Allen, P.5    Martin-Santos, R.6
  • 198
    • 78650625479 scopus 로고    scopus 로고
    • Neural basis of anxiolytic effects of cannabidiol (CBD) in generalized social anxiety disorder: a preliminary report
    • doi:10.1177/0269881110379283
    • Crippa JA, Derenusson GN, Ferrari TB, Wichert-Ana L, Duran FL, Martin-Santos R, et al. Neural basis of anxiolytic effects of cannabidiol (CBD) in generalized social anxiety disorder: a preliminary report. J Psychopharmacol (2011) 25:121-30. doi:10.1177/0269881110379283.
    • (2011) J Psychopharmacol , vol.25 , pp. 121-130
    • Crippa, J.A.1    Derenusson, G.N.2    Ferrari, T.B.3    Wichert-Ana, L.4    Duran, F.L.5    Martin-Santos, R.6
  • 199
    • 77953542908 scopus 로고    scopus 로고
    • Modulation of effective connectivity during emotional processing by Delta 9-tetrahydrocannabinol and cannabidiol
    • doi:10.1017/S1461145709990617
    • Fusar-Poli P, Allen P, Bhattacharyya S, Crippa JA, Mechelli A, Borgwardt S, et al. Modulation of effective connectivity during emotional processing by Delta 9-tetrahydrocannabinol and cannabidiol. Int J Neuropsychopharmacol (2010) 13(4): 421-32. doi:10.1017/S1461145709990617.
    • (2010) Int J Neuropsychopharmacol , vol.13 , Issue.4 , pp. 421-32
    • Fusar-Poli, P.1    Allen, P.2    Bhattacharyya, S.3    Crippa, J.A.4    Mechelli, A.5    Borgwardt, S.6
  • 200
    • 38349119146 scopus 로고    scopus 로고
    • On the relationship between emotion and cognition
    • doi:10.1038/nrn2317
    • Pessoa L. On the relationship between emotion and cognition. Nat Rev Neurosci (2008) 9:148-58. doi:10.1038/nrn2317.
    • (2008) Nat Rev Neurosci , vol.9 , pp. 148-158
    • Pessoa, L.1
  • 201
    • 77955168120 scopus 로고    scopus 로고
    • Cannabidiol inhibitory effect on marble-burying behaviour: involvement of CB1 receptors
    • doi:10.1097/FBP.0b013e32833b33c5
    • Casarotto PC, Gomes FV, Resstel LB, Guimaraes FS. Cannabidiol inhibitory effect on marble-burying behaviour: involvement of CB1 receptors. Behav Pharmacol (2010) 21:353-8. doi:10.1097/FBP.0b013e32833b33c5.
    • (2010) Behav Pharmacol , vol.21 , pp. 353-358
    • Casarotto, P.C.1    Gomes, F.V.2    Resstel, L.B.3    Guimaraes, F.S.4
  • 202
    • 84856628201 scopus 로고    scopus 로고
    • Plasma and brain pharmacokinetic profile of cannabidiol (CBD), cannabidivarine (CBDV), Delta(9)-tetrahydrocannabivarin (THCV) and cannabigerol (CBG) in rats and mice following oral and intraperitoneal administration and CBD action on obsessive-compulsive behaviour
    • Deiana S, Watanabe A, Yamasaki Y, Amada N, Arthur M, Fleming S, et al. Plasma and brain pharmacokinetic profile of cannabidiol (CBD), cannabidivarine (CBDV), Delta(9)-tetrahydrocannabivarin (THCV) and cannabigerol (CBG) in rats and mice following oral and intraperitoneal administration and CBD action on obsessive-compulsive behaviour. Psychopharmacology (Berl) (2012) 219(3):859-73.
    • (2012) Psychopharmacology (Berl) , vol.219 , Issue.3 , pp. 859-873
    • Deiana, S.1    Watanabe, A.2    Yamasaki, Y.3    Amada, N.4    Arthur, M.5    Fleming, S.6
  • 203
    • 0036838389 scopus 로고    scopus 로고
    • Cannabidiol: an overview of some pharmacological aspects
    • Mechoulam R, Parker LA, Gallily R. Cannabidiol: an overview of some pharmacological aspects. J Clin Pharmacol (2002) 42:11S-9S.
    • (2002) J Clin Pharmacol , vol.42
    • Mechoulam, R.1    Parker, L.A.2    Gallily, R.3
  • 204
    • 17444370570 scopus 로고    scopus 로고
    • Cannabinoids provide neuroprotection against 6-hydroxydopamine toxicity in vivo and in vitro: relevance to Parkinson's disease
    • doi:10.1016/j.nbd.2004.11.009
    • Lastres-Becker I, Molina-Holgado F, Ramos JA, Mechoulam R, Fernandez-Ruiz J. Cannabinoids provide neuroprotection against 6-hydroxydopamine toxicity in vivo and in vitro: relevance to Parkinson's disease. Neurobiol Dis (2005) 19:96-107. doi:10.1016/j.nbd.2004.11.009.
    • (2005) Neurobiol Dis , vol.19 , pp. 96-107
    • Lastres-Becker, I.1    Molina-Holgado, F.2    Ramos, J.A.3    Mechoulam, R.4    Fernandez-Ruiz, J.5
  • 205
    • 28944437048 scopus 로고    scopus 로고
    • Cannabinoids: between neuroprotection and neurotoxicity
    • doi:10.2174/156800705774933005
    • Sarne Y, Mechoulam R. Cannabinoids: between neuroprotection and neurotoxicity. Curr Drug Targets CNS Neurol Disord (2005) 4:677-84. doi:10.2174/156800705774933005.
    • (2005) Curr Drug Targets CNS Neurol Disord , vol.4 , pp. 677-684
    • Sarne, Y.1    Mechoulam, R.2
  • 206
    • 64849106877 scopus 로고    scopus 로고
    • Modulation of mediotemporal and ventrostriatal function in humans by Delta9-tetrahydrocannabinol: a neural basis for the effects of Cannabis sativa on learning and psychosis
    • doi:10.1001/archgenpsychiatry.2009.17
    • Bhattacharyya S, Fusar-Poli P, Borgwardt S, Martin-Santos R, Nosarti C, O'Carroll C, et al. Modulation of mediotemporal and ventrostriatal function in humans by Delta9-tetrahydrocannabinol: a neural basis for the effects of Cannabis sativa on learning and psychosis. Arch Gen Psychiatry (2009) 66:442-51. doi:10.1001/archgenpsychiatry.2009.17.
    • (2009) Arch Gen Psychiatry , vol.66 , pp. 442-451
    • Bhattacharyya, S.1    Fusar-Poli, P.2    Borgwardt, S.3    Martin-Santos, R.4    Nosarti, C.5    O'Carroll, C.6
  • 207
    • 75749126485 scopus 로고    scopus 로고
    • Opposite effects of delta-9-tetrahydrocannabinol and cannabidiol on human brain function and psychopathology
    • doi:10.1038/npp.2009.184
    • Bhattacharyya S, Morrison PD, Fusar-Poli P, Martin-Santos R, Borgwardt S, Winton-Brown T, et al. Opposite effects of delta-9-tetrahydrocannabinol and cannabidiol on human brain function and psychopathology. Neuropsychopharmacology (2010) 35:764-74. doi:10.1038/npp.2009.184.
    • (2010) Neuropsychopharmacology , vol.35 , pp. 764-774
    • Bhattacharyya, S.1    Morrison, P.D.2    Fusar-Poli, P.3    Martin-Santos, R.4    Borgwardt, S.5    Winton-Brown, T.6
  • 208
    • 55349114694 scopus 로고    scopus 로고
    • Neural basis of delta-9-tetrahydrocannabinol and cannabidiol: effects during response inhibition
    • doi:10.1016/j.biopsych.2008.05.011
    • Borgwardt SJ, Allen P, Bhattacharyya S, Fusar-Poli P, Crippa JA, Seal ML, et al. Neural basis of delta-9-tetrahydrocannabinol and cannabidiol: effects during response inhibition. Biol Psychiatry (2008) 64:966-73. doi:10.1016/j.biopsych.2008.05.011.
    • (2008) Biol Psychiatry , vol.64 , pp. 966-973
    • Borgwardt, S.J.1    Allen, P.2    Bhattacharyya, S.3    Fusar-Poli, P.4    Crippa, J.A.5    Seal, M.L.6
  • 209
    • 39149106108 scopus 로고    scopus 로고
    • Enhanced sensitivity to stress and drug/alcohol craving in abstinent cocaine-dependent individuals compared to social drinkers
    • doi:10.1038/sj.npp.1301470
    • Fox HC, Hong KI, Siedlarz K, Sinha R. Enhanced sensitivity to stress and drug/alcohol craving in abstinent cocaine-dependent individuals compared to social drinkers. Neuropsychopharmacology (2008) 33:796-805. doi:10.1038/sj.npp.1301470.
    • (2008) Neuropsychopharmacology , vol.33 , pp. 796-805
    • Fox, H.C.1    Hong, K.I.2    Siedlarz, K.3    Sinha, R.4
  • 210
    • 51349141952 scopus 로고    scopus 로고
    • Endocannabinoid signaling as a synaptic circuit breaker in neurological disease
    • doi:10.1038/nm.f.1869
    • Katona I, Freund TF. Endocannabinoid signaling as a synaptic circuit breaker in neurological disease. Nat Med (2008) 14:923-30. doi:10.1038/nm.f.1869.
    • (2008) Nat Med , vol.14 , pp. 923-930
    • Katona, I.1    Freund, T.F.2
  • 211
    • 41149089597 scopus 로고    scopus 로고
    • Glutamate release in the nucleus accumbens core is necessary for heroin seeking
    • doi:10.1523/JNEUROSCI.5129-07.2008
    • Lalumiere RT, Kalivas PW. Glutamate release in the nucleus accumbens core is necessary for heroin seeking. J Neurosci (2008) 28:3170-7. doi:10.1523/JNEUROSCI.5129-07.2008.
    • (2008) J Neurosci , vol.28 , pp. 3170-3177
    • Lalumiere, R.T.1    Kalivas, P.W.2
  • 212
    • 39149092685 scopus 로고    scopus 로고
    • Divergent effects of cannabidiol on the discriminative stimulus and place conditioning effects of Delta(9)-tetrahydrocannabinol
    • doi:10.1016/j.drugalcdep.2007.11.017
    • Vann RE, Gamage TF, Warner JA, Marshall EM, Taylor NL, Martin BR, et al. Divergent effects of cannabidiol on the discriminative stimulus and place conditioning effects of Delta(9)-tetrahydrocannabinol. Drug Alcohol Depend (2008) 94:191-8. doi:10.1016/j.drugalcdep.2007.11.017.
    • (2008) Drug Alcohol Depend , vol.94 , pp. 191-198
    • Vann, R.E.1    Gamage, T.F.2    Warner, J.A.3    Marshall, E.M.4    Taylor, N.L.5    Martin, B.R.6
  • 213
    • 67649274432 scopus 로고    scopus 로고
    • Cannabidiol reverses the reduction in social interaction produced by low dose Delta(9)-tetrahydrocannabinol in rats
    • doi:10.1016/j.pbb.2009.04.010
    • Malone DT, Jongejan D, Taylor DA. Cannabidiol reverses the reduction in social interaction produced by low dose Delta(9)-tetrahydrocannabinol in rats. Pharmacol Biochem Behav (2009) 93:91-6. doi:10.1016/j.pbb.2009.04.010.
    • (2009) Pharmacol Biochem Behav , vol.93 , pp. 91-96
    • Malone, D.T.1    Jongejan, D.2    Taylor, D.A.3
  • 214
    • 0016135039 scopus 로고
    • Effects of delta9-tetrahydrocannabinol and cannabinol on operant performance in rats
    • Karniol IG, Takahashi RN, Musty RE. Effects of delta9-tetrahydrocannabinol and cannabinol on operant performance in rats. Arch Int Pharmacodyn Ther (1974) 212:230-7.
    • (1974) Arch Int Pharmacodyn Ther , vol.212 , pp. 230-237
    • Karniol, I.G.1    Takahashi, R.N.2    Musty, R.E.3
  • 215
    • 0020079139 scopus 로고
    • Action of cannabidiol on the anxiety and other effects produced by delta 9-THC in normal subjects
    • doi:10.1007/BF00432554
    • Zuardi AW, Shirakawa I, Finkelfarb E, Karniol IG. Action of cannabidiol on the anxiety and other effects produced by delta 9-THC in normal subjects. Psychopharmacology (Berl) (1982) 76:245-50. doi:10.1007/BF00432554.
    • (1982) Psychopharmacology (Berl) , vol.76 , pp. 245-250
    • Zuardi, A.W.1    Shirakawa, I.2    Finkelfarb, E.3    Karniol, I.G.4
  • 216
    • 12744258029 scopus 로고    scopus 로고
    • Inverse agonism and neutral antagonism at cannabinoid CB1 receptors
    • doi:10.1016/j.lfs.2004.10.025
    • Pertwee RG. Inverse agonism and neutral antagonism at cannabinoid CB1 receptors. Life Sci (2005) 76:1307-24. doi:10.1016/j.lfs.2004.10.025.
    • (2005) Life Sci , vol.76 , pp. 1307-1324
    • Pertwee, R.G.1
  • 217
    • 28844489930 scopus 로고    scopus 로고
    • A tale of two cannabinoids: the therapeutic rationale for combining tetrahydrocannabinol and cannabidiol
    • doi:10.1016/j.mehy.2005.08.026
    • Russo E, Guy GW. A tale of two cannabinoids: the therapeutic rationale for combining tetrahydrocannabinol and cannabidiol. Med Hypotheses (2006) 66:234-46. doi:10.1016/j.mehy.2005.08.026.
    • (2006) Med Hypotheses , vol.66 , pp. 234-246
    • Russo, E.1    Guy, G.W.2
  • 218
    • 72449197981 scopus 로고    scopus 로고
    • Cannabidiol, a nonpsychotropic component of cannabis, inhibits cue-induced heroin seeking and normalizes discrete mesolimbic neuronal disturbances
    • doi:10.1523/JNEUROSCI.4291-09.2009
    • Ren Y, Whittard J, Higuera-Matas A, Morris CV, Hurd YL. Cannabidiol, a nonpsychotropic component of cannabis, inhibits cue-induced heroin seeking and normalizes discrete mesolimbic neuronal disturbances. J Neurosci (2009) 29:14764-9. doi:10.1523/JNEUROSCI.4291-09.2009.
    • (2009) J Neurosci , vol.29 , pp. 14764-9
    • Ren, Y.1    Whittard, J.2    Higuera-Matas, A.3    Morris, C.V.4    Hurd, Y.L.5
  • 219
    • 22944458873 scopus 로고    scopus 로고
    • Comparison of cannabidiol, antioxidants, and diuretics in reversing binge ethanol-induced neurotoxicity
    • doi:10.1124/jpet.105.085779
    • Hamelink C, Hampson A, Wink DA, Eiden LE, Eskay RL. Comparison of cannabidiol, antioxidants, and diuretics in reversing binge ethanol-induced neurotoxicity. J Pharmacol Exp Ther (2005) 314:780-8. doi:10.1124/jpet.105.085779.
    • (2005) J Pharmacol Exp Ther , vol.314 , pp. 780-788
    • Hamelink, C.1    Hampson, A.2    Wink, D.A.3    Eiden, L.E.4    Eskay, R.L.5
  • 220
    • 0021015357 scopus 로고
    • Antagonistic effects of two natural cannabinoids on the isolated heart
    • Trouve R, Nahas G, Stuker O, Latour C. Antagonistic effects of two natural cannabinoids on the isolated heart. C R Seances Acad Sci III (1983) 297:191-4.
    • (1983) C R Seances Acad Sci III , vol.297 , pp. 191-194
    • Trouve, R.1    Nahas, G.2    Stuker, O.3    Latour, C.4
  • 221
    • 0022351916 scopus 로고
    • Effects and interactions of natural cannabinoids on the isolated heart
    • doi:10.3181/00379727-180-42181
    • Nahas G, Trouve R. Effects and interactions of natural cannabinoids on the isolated heart. Proc Soc Exp Biol Med (1985) 180:312-6. doi:10.3181/00379727-180-42181.
    • (1985) Proc Soc Exp Biol Med , vol.180 , pp. 312-316
    • Nahas, G.1    Trouve, R.2
  • 222
    • 1842509987 scopus 로고    scopus 로고
    • Cannabis and other illicit drugs: comorbid use and abuse/dependence in males and females
    • doi:10.1023/B:BEGE.0000017868.07829.45
    • Agrawal A, Neale MC, Prescott CA, Kendler KS. Cannabis and other illicit drugs: comorbid use and abuse/dependence in males and females. Behav Genet (2004) 34:217-28. doi:10.1023/B:BEGE.0000017868.07829.45.
    • (2004) Behav Genet , vol.34 , pp. 217-228
    • Agrawal, A.1    Neale, M.C.2    Prescott, C.A.3    Kendler, K.S.4
  • 223
    • 0025163426 scopus 로고
    • The prevalence of marijuana (cannabis) use and dependence in cocaine dependence
    • Miller NS, Klahr AL, Gold MS, Sweeney K, Cocores JA. The prevalence of marijuana (cannabis) use and dependence in cocaine dependence. N Y State J Med (1990) 90:491-2.
    • (1990) N Y State J Med , vol.90 , pp. 491-492
    • Miller, N.S.1    Klahr, A.L.2    Gold, M.S.3    Sweeney, K.4    Cocores, J.A.5
  • 224
    • 80054990781 scopus 로고    scopus 로고
    • Endocannabinoid influence in drug reinforcement, dependence and addiction-related behaviors
    • doi:10.1016/j.pharmthera.2011.06.005
    • Serrano A, Parsons LH. Endocannabinoid influence in drug reinforcement, dependence and addiction-related behaviors. Pharmacol Ther (2011) 132:215-41. doi:10.1016/j.pharmthera.2011.06.005.
    • (2011) Pharmacol Ther , vol.132 , pp. 215-241
    • Serrano, A.1    Parsons, L.H.2
  • 225
    • 33644863295 scopus 로고    scopus 로고
    • Cannabis use and other illicit drug use: testing the cannabis gateway hypothesis
    • doi:10.1111/j.1360-0443.2005.01322.x
    • Fergusson DM, Boden JM, Horwood LJ. Cannabis use and other illicit drug use: testing the cannabis gateway hypothesis. Addiction (2006) 101:556-69. doi:10.1111/j.1360-0443.2005.01322.x.
    • (2006) Addiction , vol.101 , pp. 556-569
    • Fergusson, D.M.1    Boden, J.M.2    Horwood, L.J.3
  • 226
    • 33644861396 scopus 로고    scopus 로고
    • Testing the gateway hypothesis
    • doi:10.1111/j.1360-0443.2006.01426.x discussion 474-476
    • Kandel DB, Yamaguchi K, Klein LC. Testing the gateway hypothesis. Addiction (2006) 101:470-2. doi:10.1111/j.1360-0443.2006.01426.x discussion 474-476.
    • (2006) Addiction , vol.101 , pp. 470-472
    • Kandel, D.B.1    Yamaguchi, K.2    Klein, L.C.3
  • 227
    • 33646344004 scopus 로고    scopus 로고
    • Early onset cannabis use and progression to other drug use in a sample of Dutch twins
    • doi:10.1007/s10519-005-9023-x
    • Lynskey MT, Vink JM, Boomsma DI. Early onset cannabis use and progression to other drug use in a sample of Dutch twins. Behav Genet (2006) 36:195-200. doi:10.1007/s10519-005-9023-x.
    • (2006) Behav Genet , vol.36 , pp. 195-200
    • Lynskey, M.T.1    Vink, J.M.2    Boomsma, D.I.3
  • 228
    • 33845968072 scopus 로고    scopus 로고
    • Contrasting models of genetic co-morbidity for cannabis and other illicit drugs in adult Australian twins
    • doi:10.1017/S0033291706009287
    • Agrawal A, Lynskey MT, Bucholz KK, Martin NG, Madden PA, Heath AC. Contrasting models of genetic co-morbidity for cannabis and other illicit drugs in adult Australian twins. Psychol Med (2007) 37:49-60. doi:10.1017/S0033291706009287.
    • (2007) Psychol Med , vol.37 , pp. 49-60
    • Agrawal, A.1    Lynskey, M.T.2    Bucholz, K.K.3    Martin, N.G.4    Madden, P.A.5    Heath, A.C.6
  • 229
    • 84867746610 scopus 로고    scopus 로고
    • Proenkephalin mediates the enduring effects of adolescent Cannabis exposure associated with adult opiate vulnerability
    • doi:10.1016/j.biopsych.2012.04.026
    • Tomasiewicz HC, Jacobs MM, Wilkinson MB, Wilson SP, Nestler EJ, Hurd YL. Proenkephalin mediates the enduring effects of adolescent Cannabis exposure associated with adult opiate vulnerability. Biol Psychiatry (2012) 72(10):803-10. doi:10.1016/j.biopsych.2012.04.026.
    • (2012) Biol Psychiatry , vol.72 , Issue.10 , pp. 803-810
    • Tomasiewicz, H.C.1    Jacobs, M.M.2    Wilkinson, M.B.3    Wilson, S.P.4    Nestler, E.J.5    Hurd, Y.L.6
  • 230
    • 0037947438 scopus 로고    scopus 로고
    • Catechol O-methyltransferase val158-met genotype and individual variation in the brain response to amphetamine
    • doi:10.1073/pnas.0931309100
    • Mattay VS, Goldberg TE, Fera F, Hariri AR, Tessitore A, Egan MF, et al. Catechol O-methyltransferase val158-met genotype and individual variation in the brain response to amphetamine. Proc Natl Acad Sci U S A (2003) 100:6186-91. doi:10.1073/pnas.0931309100.
    • (2003) Proc Natl Acad Sci U S A , vol.100 , pp. 6186-6191
    • Mattay, V.S.1    Goldberg, T.E.2    Fera, F.3    Hariri, A.R.4    Tessitore, A.5    Egan, M.F.6
  • 231
    • 0036741356 scopus 로고    scopus 로고
    • The amygdala response to emotional stimuli: a comparison of faces and scenes
    • doi:10.1006/nimg.2002.1179
    • Hariri AR, Tessitore A, Mattay VS, Fera F, Weinberger DR. The amygdala response to emotional stimuli: a comparison of faces and scenes. Neuroimage (2002) 17:317-23. doi:10.1006/nimg.2002.1179.
    • (2002) Neuroimage , vol.17 , pp. 317-323
    • Hariri, A.R.1    Tessitore, A.2    Mattay, V.S.3    Fera, F.4    Weinberger, D.R.5
  • 233
    • 0027336093 scopus 로고
    • Decreased dopamine D2 receptor availability is associated with reduced frontal metabolism in cocaine abusers
    • doi:10.1002/syn.890140210
    • Volkow ND, Fowler JS, Wang GJ, Hitzemann R, Logan J, Schlyer DJ, et al. Decreased dopamine D2 receptor availability is associated with reduced frontal metabolism in cocaine abusers. Synapse (1993) 14:169-77. doi:10.1002/syn.890140210.
    • (1993) Synapse , vol.14 , pp. 169-177
    • Volkow, N.D.1    Fowler, J.S.2    Wang, G.J.3    Hitzemann, R.4    Logan, J.5    Schlyer, D.J.6
  • 234
    • 0035191931 scopus 로고    scopus 로고
    • Low level of brain dopamine D2 receptors in methamphetamine abusers: association with metabolism in the orbitofrontal cortex
    • doi:10.1176/appi.ajp.158.12.2015
    • Volkow ND, Chang L, Wang GJ, Fowler JS, Ding YS, Sedler M, et al. Low level of brain dopamine D2 receptors in methamphetamine abusers: association with metabolism in the orbitofrontal cortex. Am J Psychiatry (2001) 158:2015-21. doi:10.1176/appi.ajp.158.12.2015.
    • (2001) Am J Psychiatry , vol.158 , pp. 2015-2021
    • Volkow, N.D.1    Chang, L.2    Wang, G.J.3    Fowler, J.S.4    Ding, Y.S.5    Sedler, M.6
  • 235
    • 45149098991 scopus 로고    scopus 로고
    • Juvenile methylphenidate modulates reward-related behaviors and cerebral blood flow by decreasing cortical D3 receptors
    • doi:10.1111/j.1460-9568.2008.06254.x
    • Andersen SL, Napierata L, Brenhouse HC, Sonntag KC. Juvenile methylphenidate modulates reward-related behaviors and cerebral blood flow by decreasing cortical D3 receptors. Eur J Neurosci (2008) 27:2962-72. doi:10.1111/j.1460-9568.2008.06254.x.
    • (2008) Eur J Neurosci , vol.27 , pp. 2962-2972
    • Andersen, S.L.1    Napierata, L.2    Brenhouse, H.C.3    Sonntag, K.C.4
  • 237
    • 33645074703 scopus 로고    scopus 로고
    • (AAT)n repeat in the cannabinoid receptor gene (CNR1): association with cocaine addiction in an African-Caribbean population
    • doi:10.1038/sj.tpj.6500352
    • Ballon N, Leroy S, Roy C, Bourdel MC, Charles-Nicolas A, Krebs MO, et al. (AAT)n repeat in the cannabinoid receptor gene (CNR1): association with cocaine addiction in an African-Caribbean population. Pharmacogenomics J (2006) 6:126-30. doi:10.1038/sj.tpj.6500352.
    • (2006) Pharmacogenomics J , vol.6 , pp. 126-130
    • Ballon, N.1    Leroy, S.2    Roy, C.3    Bourdel, M.C.4    Charles-Nicolas, A.5    Krebs, M.O.6
  • 238
    • 2442701496 scopus 로고    scopus 로고
    • Microsatellites within genes: structure, function, and evolution
    • doi:10.1093/molbev/msh073
    • Li YC, Korol AB, Fahima T, Nevo E. Microsatellites within genes: structure, function, and evolution. Mol Biol Evol (2004) 21:991-1007. doi:10.1093/molbev/msh073.
    • (2004) Mol Biol Evol , vol.21 , pp. 991-1007
    • Li, Y.C.1    Korol, A.B.2    Fahima, T.3    Nevo, E.4
  • 239
    • 78649976095 scopus 로고    scopus 로고
    • CNR1 gene polymorphisms in addictive disorders: a systematic review and a meta-analysis
    • doi:10.1111/j.1369-1600.2009.00198.x
    • Benyamina A, Kebir O, Blecha L, Reynaud M, Krebs MO. CNR1 gene polymorphisms in addictive disorders: a systematic review and a meta-analysis. Addict Biol (2011) 16:1-6. doi:10.1111/j.1369-1600.2009.00198.x.
    • (2011) Addict Biol , vol.16 , pp. 1-6
    • Benyamina, A.1    Kebir, O.2    Blecha, L.3    Reynaud, M.4    Krebs, M.O.5
  • 240
    • 16344376222 scopus 로고    scopus 로고
    • Depression in Parkinson's disease is related to a genetic polymorphism of the cannabinoid receptor gene (CNR1)
    • doi:10.1038/sj.tpj.6500301
    • Barrero FJ, Ampuero I, Morales B, Vives F, De Dios Luna Del Castillo J, Hoenicka J, et al. Depression in Parkinson's disease is related to a genetic polymorphism of the cannabinoid receptor gene (CNR1). Pharmacogenomics J (2005) 5:135-41. doi:10.1038/sj.tpj.6500301.
    • (2005) Pharmacogenomics J , vol.5 , pp. 135-141
    • Barrero, F.J.1    Ampuero, I.2    Morales, B.3    Vives, F.4    De Dios Luna Del Castillo, J.5    Hoenicka, J.6
  • 241
    • 51249092085 scopus 로고    scopus 로고
    • Marijuana withdrawal and craving: influence of the cannabinoid receptor 1 (CNR1) and fatty acid amide hydrolase (FAAH) genes
    • doi:10.1111/j.1360-0443.2008.02292.x
    • Haughey HM, Marshall E, Schacht JP, Louis A, Hutchison KE. Marijuana withdrawal and craving: influence of the cannabinoid receptor 1 (CNR1) and fatty acid amide hydrolase (FAAH) genes. Addiction (2008) 103:1678-86. doi:10.1111/j.1360-0443.2008.02292.x.
    • (2008) Addiction , vol.103 , pp. 1678-1686
    • Haughey, H.M.1    Marshall, E.2    Schacht, J.P.3    Louis, A.4    Hutchison, K.E.5
  • 242
    • 76749109409 scopus 로고    scopus 로고
    • Individual and additive effects of the CNR1 and FAAH genes on brain response to marijuana cues
    • doi:10.1038/npp.2009.200
    • Filbey FM, Schacht JP, Myers US, Chavez RS, Hutchison KE. Individual and additive effects of the CNR1 and FAAH genes on brain response to marijuana cues. Neuropsychopharmacology (2010) 35:967-75. doi:10.1038/npp.2009.200.
    • (2010) Neuropsychopharmacology , vol.35 , pp. 967-975
    • Filbey, F.M.1    Schacht, J.P.2    Myers, U.S.3    Chavez, R.S.4    Hutchison, K.E.5
  • 243
    • 84856486914 scopus 로고    scopus 로고
    • The genetic basis of the endocannabinoid system and drug addiction in humans
    • doi:10.1177/0269881111416689
    • Lopez-Moreno JA, Echeverry-Alzate V, Buhler KM. The genetic basis of the endocannabinoid system and drug addiction in humans. J Psychopharmacol (2012) 26:133-43. doi:10.1177/0269881111416689.
    • (2012) J Psychopharmacol , vol.26 , pp. 133-143
    • Lopez-Moreno, J.A.1    Echeverry-Alzate, V.2    Buhler, K.M.3
  • 244
    • 84879464553 scopus 로고    scopus 로고
    • Further evidence for association of polymorphisms in the CNR1 gene with cocaine addiction: confirmation in an independent sample and meta-analysis
    • doi:10.1111/j.1369-1600.2011.00346.x
    • Clarke TK, Bloch PJ, Ambrose-Lanci LM, Ferraro TN, Berrettini WH, Kampman KM, et al. Further evidence for association of polymorphisms in the CNR1 gene with cocaine addiction: confirmation in an independent sample and meta-analysis. Addict Biol (2013) 18(4):702-8. doi:10.1111/j.1369-1600.2011.00346.x.
    • (2013) Addict Biol , vol.18 , Issue.4 , pp. 702-708
    • Clarke, T.K.1    Bloch, P.J.2    Ambrose-Lanci, L.M.3    Ferraro, T.N.4    Berrettini, W.H.5    Kampman, K.M.6
  • 245
    • 0037062436 scopus 로고    scopus 로고
    • A missense mutation in human fatty acid amide hydrolase associated with problem drug use
    • doi:10.1073/pnas.082235799
    • Sipe JC, Chiang K, Gerber AL, Beutler E, Cravatt BF. A missense mutation in human fatty acid amide hydrolase associated with problem drug use. Proc Natl Acad Sci U S A (2002) 99:8394-9. doi:10.1073/pnas.082235799.
    • (2002) Proc Natl Acad Sci U S A , vol.99 , pp. 8394-8399
    • Sipe, J.C.1    Chiang, K.2    Gerber, A.L.3    Beutler, E.4    Cravatt, B.F.5
  • 246
    • 33750570881 scopus 로고    scopus 로고
    • The fatty acid amide hydrolase 385 A/A (P129T) variant: haplotype analysis of an ancient missense mutation and validation of risk for drug addiction
    • doi:10.1007/s00439-006-0250-x
    • Flanagan JM, Gerber AL, Cadet JL, Beutler E, Sipe JC. The fatty acid amide hydrolase 385 A/A (P129T) variant: haplotype analysis of an ancient missense mutation and validation of risk for drug addiction. Hum Genet (2006) 120:581-8. doi:10.1007/s00439-006-0250-x.
    • (2006) Hum Genet , vol.120 , pp. 581-588
    • Flanagan, J.M.1    Gerber, A.L.2    Cadet, J.L.3    Beutler, E.4    Sipe, J.C.5
  • 247
    • 27844552398 scopus 로고    scopus 로고
    • Recent cannabis abuse decreased stress-induced BOLD signals in the frontal and cingulate cortices of cocaine dependent individuals
    • doi:10.1016/j.pscychresns.2005.09.002
    • Li CS, Milivojevic V, Constable RT, Sinha R. Recent cannabis abuse decreased stress-induced BOLD signals in the frontal and cingulate cortices of cocaine dependent individuals. Psychiatry Res (2005) 140:271-80. doi:10.1016/j.pscychresns.2005.09.002.
    • (2005) Psychiatry Res , vol.140 , pp. 271-280
    • Li, C.S.1    Milivojevic, V.2    Constable, R.T.3    Sinha, R.4
  • 248
    • 0027231882 scopus 로고
    • Behavioral effects of cocaine alone and in combination with ethanol or marijuana in humans
    • doi:10.1016/0376-8716(93)80001-U
    • Foltin RW, Fischman MW, Pippen PA, Kelly TH. Behavioral effects of cocaine alone and in combination with ethanol or marijuana in humans. Drug Alcohol Depend (1993) 32:93-106. doi:10.1016/0376-8716(93)80001-U.
    • (1993) Drug Alcohol Depend , vol.32 , pp. 93-106
    • Foltin, R.W.1    Fischman, M.W.2    Pippen, P.A.3    Kelly, T.H.4
  • 249
    • 0028338684 scopus 로고
    • Marihuana smoking increases plasma cocaine levels and subjective reports of euphoria in male volunteers
    • doi:10.1016/0091-3057(94)90338-7
    • Lukas SE, Sholar M, Kouri E, Fukuzako H, Mendelson JH. Marihuana smoking increases plasma cocaine levels and subjective reports of euphoria in male volunteers. Pharmacol Biochem Behav (1994) 48:715-21. doi:10.1016/0091-3057(94)90338-7.
    • (1994) Pharmacol Biochem Behav , vol.48 , pp. 715-721
    • Lukas, S.E.1    Sholar, M.2    Kouri, E.3    Fukuzako, H.4    Mendelson, J.H.5
  • 250
    • 43449130829 scopus 로고    scopus 로고
    • Cannabinoid CB1 receptor antagonists attenuate cocaine's rewarding effects: experiments with self-administration and brain-stimulation reward in rats
    • doi:10.1038/sj.npp.1301552
    • Xi ZX, Spiller K, Pak AC, Gilbert J, Dillon C, Li X, et al. Cannabinoid CB1 receptor antagonists attenuate cocaine's rewarding effects: experiments with self-administration and brain-stimulation reward in rats. Neuropsychopharmacology (2008) 33:1735-45. doi:10.1038/sj.npp.1301552.
    • (2008) Neuropsychopharmacology , vol.33 , pp. 1735-1745
    • Xi, Z.X.1    Spiller, K.2    Pak, A.C.3    Gilbert, J.4    Dillon, C.5    Li, X.6
  • 251
    • 0038079373 scopus 로고    scopus 로고
    • WIN 55,212-2 decreases the reinforcing actions of cocaine through CB1 cannabinoid receptor stimulation
    • doi:10.1016/S0166-4328(02)00370-4
    • Vlachou S, Nomikos GG, Panagis G. WIN 55,212-2 decreases the reinforcing actions of cocaine through CB1 cannabinoid receptor stimulation. Behav Brain Res (2003) 141:215-22. doi:10.1016/S0166-4328(02)00370-4.
    • (2003) Behav Brain Res , vol.141 , pp. 215-222
    • Vlachou, S.1    Nomikos, G.G.2    Panagis, G.3
  • 252
    • 53049091088 scopus 로고    scopus 로고
    • Enhancement of endocannabinoid neurotransmission through CB1 cannabinoid receptors counteracts the reinforcing and psychostimulant effects of cocaine
    • doi:10.1017/S1461145708008717
    • Vlachou S, Stamatopoulou F, Nomikos GG, Panagis G. Enhancement of endocannabinoid neurotransmission through CB1 cannabinoid receptors counteracts the reinforcing and psychostimulant effects of cocaine. Int J Neuropsychopharmacol (2008) 11:905-23. doi:10.1017/S1461145708008717.
    • (2008) Int J Neuropsychopharmacol , vol.11 , pp. 905-923
    • Vlachou, S.1    Stamatopoulou, F.2    Nomikos, G.G.3    Panagis, G.4
  • 253
    • 67349137069 scopus 로고    scopus 로고
    • Attenuation of basal and cocaine-enhanced locomotion and nucleus accumbens dopamine in cannabinoid CB1-receptor-knockout mice
    • doi:10.1007/s00213-008-1432-0
    • Li X, Hoffman AF, Peng XQ, Lupica CR, Gardner EL, Xi ZX. Attenuation of basal and cocaine-enhanced locomotion and nucleus accumbens dopamine in cannabinoid CB1-receptor-knockout mice. Psychopharmacology (Berl) (2009) 204:1-11. doi:10.1007/s00213-008-1432-0.
    • (2009) Psychopharmacology (Berl) , vol.204 , pp. 1-11
    • Li, X.1    Hoffman, A.F.2    Peng, X.Q.3    Lupica, C.R.4    Gardner, E.L.5    Xi, Z.X.6
  • 254
    • 33846596719 scopus 로고    scopus 로고
    • Phasic dopamine release evoked by abused substances requires cannabinoid receptor activation
    • doi:10.1523/JNEUROSCI.4152-06.2007
    • Cheer JF, Wassum KM, Sombers LA, Heien ML, Ariansen JL, Aragona BJ, et al. Phasic dopamine release evoked by abused substances requires cannabinoid receptor activation. J Neurosci (2007) 27:791-5. doi:10.1523/JNEUROSCI.4152-06.2007.
    • (2007) J Neurosci , vol.27 , pp. 791-795
    • Cheer, J.F.1    Wassum, K.M.2    Sombers, L.A.3    Heien, M.L.4    Ariansen, J.L.5    Aragona, B.J.6
  • 256
    • 33645034385 scopus 로고    scopus 로고
    • Cannabinoid modulation of opiate reinforcement through the ventral striatopallidal pathway
    • doi:10.1038/sj.npp.1300848
    • Caille S, Parsons LH. Cannabinoid modulation of opiate reinforcement through the ventral striatopallidal pathway. Neuropsychopharmacology (2006) 31:804-13. doi:10.1038/sj.npp.1300848.
    • (2006) Neuropsychopharmacology , vol.31 , pp. 804-813
    • Caille, S.1    Parsons, L.H.2
  • 257
    • 33748158341 scopus 로고    scopus 로고
    • Cannabinoid CB1 receptor antagonist AM251 inhibits cocaine-primed relapse in rats: role of glutamate in the nucleus accumbens
    • doi:10.1523/JNEUROSCI.0726-06.2006
    • Xi ZX, Gilbert JG, Peng XQ, Pak AC, Li X, Gardner EL. Cannabinoid CB1 receptor antagonist AM251 inhibits cocaine-primed relapse in rats: role of glutamate in the nucleus accumbens. J Neurosci (2006) 26:8531-6. doi:10.1523/JNEUROSCI.0726-06.2006.
    • (2006) J Neurosci , vol.26 , pp. 8531-8536
    • Xi, Z.X.1    Gilbert, J.G.2    Peng, X.Q.3    Pak, A.C.4    Li, X.5    Gardner, E.L.6
  • 258
    • 80052213796 scopus 로고    scopus 로고
    • Brain cannabinoid CB(2) receptors modulate cocaine's actions in mice
    • doi:10.1038/nn.2874
    • Xi ZX, Peng XQ, Li X, Song R, Zhang HY, Liu QR, et al. Brain cannabinoid CB(2) receptors modulate cocaine's actions in mice. Nat Neurosci (2011) 14:1160-6. doi:10.1038/nn.2874.
    • (2011) Nat Neurosci , vol.14 , pp. 1160-1166
    • Xi, Z.X.1    Peng, X.Q.2    Li, X.3    Song, R.4    Zhang, H.Y.5    Liu, Q.R.6
  • 259
    • 77953207747 scopus 로고    scopus 로고
    • Effects of fatty acid amide hydrolase inhibition on neuronal responses to nicotine, cocaine and morphine in the nucleus accumbens shell and ventral tegmental area: involvement of PPAR-alpha nuclear receptors
    • doi:10.1111/j.1369-1600.2010.00222.x
    • Luchicchi A, Lecca S, Carta S, Pillolla G, Muntoni AL, Yasar S, et al. Effects of fatty acid amide hydrolase inhibition on neuronal responses to nicotine, cocaine and morphine in the nucleus accumbens shell and ventral tegmental area: involvement of PPAR-alpha nuclear receptors. Addict Biol (2010) 15:277-88. doi:10.1111/j.1369-1600.2010.00222.x.
    • (2010) Addict Biol , vol.15 , pp. 277-288
    • Luchicchi, A.1    Lecca, S.2    Carta, S.3    Pillolla, G.4    Muntoni, A.L.5    Yasar, S.6
  • 260
    • 54349109924 scopus 로고    scopus 로고
    • Fatty acid amide hydrolase inhibition heightens anandamide signaling without producing reinforcing effects in primates
    • doi:10.1016/j.biopsych.2008.08.008
    • Justinova Z, Mangieri RA, Bortolato M, Chefer SI, Mukhin AG, Clapper JR, et al. Fatty acid amide hydrolase inhibition heightens anandamide signaling without producing reinforcing effects in primates. Biol Psychiatry (2008) 64:930-7. doi:10.1016/j.biopsych.2008.08.008.
    • (2008) Biol Psychiatry , vol.64 , pp. 930-937
    • Justinova, Z.1    Mangieri, R.A.2    Bortolato, M.3    Chefer, S.I.4    Mukhin, A.G.5    Clapper, J.R.6
  • 261
    • 70350217362 scopus 로고    scopus 로고
    • The effects of fatty acid amide hydrolase inhibitors on maintenance of cocaine and food self-administration and on reinstatement of cocaine-seeking and food-taking behavior in rats
    • Adamczyk P, McCreary AC, Przegalinski E, Mierzejewski P, Bienkowski P, Filip M. The effects of fatty acid amide hydrolase inhibitors on maintenance of cocaine and food self-administration and on reinstatement of cocaine-seeking and food-taking behavior in rats. J Physiol Pharmacol (2009) 60:119-25.
    • (2009) J Physiol Pharmacol , vol.60 , pp. 119-125
    • Adamczyk, P.1    McCreary, A.C.2    Przegalinski, E.3    Mierzejewski, P.4    Bienkowski, P.5    Filip, M.6
  • 262
    • 0033777338 scopus 로고    scopus 로고
    • Cocaine, but not morphine, induces conditioned place preference and sensitization to locomotor responses in CB1 knockout mice
    • doi:10.1046/j.1460-9568.2000.00287.x
    • Martin M, Ledent C, Parmentier M, Maldonado R, Valverde O. Cocaine, but not morphine, induces conditioned place preference and sensitization to locomotor responses in CB1 knockout mice. Eur J Neurosci (2000) 12:4038-46. doi:10.1046/j.1460-9568.2000.00287.x.
    • (2000) Eur J Neurosci , vol.12 , pp. 4038-4046
    • Martin, M.1    Ledent, C.2    Parmentier, M.3    Maldonado, R.4    Valverde, O.5
  • 263
    • 12344282798 scopus 로고    scopus 로고
    • CB1 receptor knockout mice display reduced ethanol-induced conditioned place preference and increased striatal dopamine D2 receptors
    • doi:10.1038/sj.npp.1300568
    • Houchi H, Babovic D, Pierrefiche O, Ledent C, Daoust M, Naassila M. CB1 receptor knockout mice display reduced ethanol-induced conditioned place preference and increased striatal dopamine D2 receptors. Neuropsychopharmacology (2005) 30:339-49. doi:10.1038/sj.npp.1300568.
    • (2005) Neuropsychopharmacology , vol.30 , pp. 339-349
    • Houchi, H.1    Babovic, D.2    Pierrefiche, O.3    Ledent, C.4    Daoust, M.5    Naassila, M.6
  • 264
    • 58149335562 scopus 로고    scopus 로고
    • Chronic unpredictable stress enhances cocaine-conditioned place preference in type 1 cannabinoid receptor knockout mice
    • doi:10.1097/FBP.0b013e32830ded11
    • Miller LL, Ward SJ, Dykstra LA. Chronic unpredictable stress enhances cocaine-conditioned place preference in type 1 cannabinoid receptor knockout mice. Behav Pharmacol (2008) 19:575-81. doi:10.1097/FBP.0b013e32830ded11.
    • (2008) Behav Pharmacol , vol.19 , pp. 575-581
    • Miller, L.L.1    Ward, S.J.2    Dykstra, L.A.3
  • 265
    • 0031780582 scopus 로고    scopus 로고
    • Involvement of central cannabinoid (CB1) receptors in the establishment of place conditioning in rats
    • doi:10.1007/s002130050518
    • Chaperon F, Soubrie P, Puech AJ, Thiebot MH. Involvement of central cannabinoid (CB1) receptors in the establishment of place conditioning in rats. Psychopharmacology (Berl) (1998) 135:324-32. doi:10.1007/s002130050518.
    • (1998) Psychopharmacology (Berl) , vol.135 , pp. 324-332
    • Chaperon, F.1    Soubrie, P.2    Puech, A.J.3    Thiebot, M.H.4
  • 266
    • 9644299710 scopus 로고    scopus 로고
    • Endogenous cannabinoids are not involved in cocaine reinforcement and development of cocaine-induced behavioural sensitization
    • doi:10.1016/j.euroneuro.2004.04.003
    • Lesscher HM, Hoogveld E, Burbach JP, Van Ree JM, Gerrits MA. Endogenous cannabinoids are not involved in cocaine reinforcement and development of cocaine-induced behavioural sensitization. Eur Neuropsychopharmacol (2005) 15:31-7. doi:10.1016/j.euroneuro.2004.04.003.
    • (2005) Eur Neuropsychopharmacol , vol.15 , pp. 31-37
    • Lesscher, H.M.1    Hoogveld, E.2    Burbach, J.P.3    Van Ree, J.M.4    Gerrits, M.A.5
  • 267
    • 34347359741 scopus 로고    scopus 로고
    • Role of cannabinoid type 1 receptors in locomotor activity and striatal signaling in response to psychostimulants
    • doi:10.1523/JNEUROSCI.3936-06.2007
    • Corbille AG, Valjent E, Marsicano G, Ledent C, Lutz B, Herve D, et al. Role of cannabinoid type 1 receptors in locomotor activity and striatal signaling in response to psychostimulants. J Neurosci (2007) 27:6937-47. doi:10.1523/JNEUROSCI.3936-06.2007.
    • (2007) J Neurosci , vol.27 , pp. 6937-6947
    • Corbille, A.G.1    Valjent, E.2    Marsicano, G.3    Ledent, C.4    Lutz, B.5    Herve, D.6
  • 268
    • 51749087269 scopus 로고    scopus 로고
    • Context-specific reversal of cocaine sensitization by the CB1 cannabinoid receptor antagonist rimonabant
    • doi:10.1038/sj.npp.1301648
    • Gerdeman GL, Schechter JB, French ED. Context-specific reversal of cocaine sensitization by the CB1 cannabinoid receptor antagonist rimonabant. Neuropsychopharmacology (2008) 33:2747-59. doi:10.1038/sj.npp.1301648.
    • (2008) Neuropsychopharmacology , vol.33 , pp. 2747-2759
    • Gerdeman, G.L.1    Schechter, J.B.2    French, E.D.3
  • 269
    • 33846323675 scopus 로고    scopus 로고
    • Involvement of cannabinoid CB1 receptors in drug addiction: effects of rimonabant on behavioral responses induced by cocaine
    • Filip M, Golda A, Zaniewska M, McCreary AC, Nowak E, Kolasiewicz W, et al. Involvement of cannabinoid CB1 receptors in drug addiction: effects of rimonabant on behavioral responses induced by cocaine. Pharmacol Rep (2006) 58:806-19.
    • (2006) Pharmacol Rep , vol.58 , pp. 806-819
    • Filip, M.1    Golda, A.2    Zaniewska, M.3    McCreary, A.C.4    Nowak, E.5    Kolasiewicz, W.6
  • 270
    • 21344470462 scopus 로고    scopus 로고
    • WIN 55,212-2-induced reduction of cocaine hyperlocomotion: possible inhibition of 5-HT(3) receptor function
    • doi:10.1016/j.ejphar.2005.05.014
    • Przegalinski E, Gothert M, Frankowska M, Filip M. WIN 55,212-2-induced reduction of cocaine hyperlocomotion: possible inhibition of 5-HT(3) receptor function. Eur J Pharmacol (2005) 517:68-73. doi:10.1016/j.ejphar.2005.05.014.
    • (2005) Eur J Pharmacol , vol.517 , pp. 68-73
    • Przegalinski, E.1    Gothert, M.2    Frankowska, M.3    Filip, M.4
  • 271
  • 272
    • 33847027722 scopus 로고    scopus 로고
    • Previous exposure to THC alters the reinforcing efficacy and anxiety-related effects of cocaine in rats
    • doi:10.1038/sj.npp.1301109
    • Panlilio LV, Solinas M, Matthews SA, Goldberg SR. Previous exposure to THC alters the reinforcing efficacy and anxiety-related effects of cocaine in rats. Neuropsychopharmacology (2007) 32:646-57. doi:10.1038/sj.npp.1301109.
    • (2007) Neuropsychopharmacology , vol.32 , pp. 646-657
    • Panlilio, L.V.1    Solinas, M.2    Matthews, S.A.3    Goldberg, S.R.4
  • 273
    • 0032587994 scopus 로고    scopus 로고
    • Chronic (-)-delta9-tetrahydrocannabinol treatment induces sensitization to the psychomotor effects of amphetamine in rats
    • doi:10.1016/S0014-2999(98)00851-6
    • Gorriti MA, Rodriguez De Fonseca F, Navarro M, Palomo T. Chronic (-)-delta9-tetrahydrocannabinol treatment induces sensitization to the psychomotor effects of amphetamine in rats. Eur J Pharmacol (1999) 365:133-42. doi:10.1016/S0014-2999(98)00851-6.
    • (1999) Eur J Pharmacol , vol.365 , pp. 133-142
    • Gorriti, M.A.1    Rodriguez De Fonseca, F.2    Navarro, M.3    Palomo, T.4
  • 274
    • 43749103518 scopus 로고    scopus 로고
    • The role of CB1 receptors in psychostimulant addiction
    • doi:10.1111/j.1369-1600.2008.00109.x
    • Wiskerke J, Pattij T, Schoffelmeer AN, De Vries TJ. The role of CB1 receptors in psychostimulant addiction. Addict Biol (2008) 13:225-38. doi:10.1111/j.1369-1600.2008.00109.x.
    • (2008) Addict Biol , vol.13 , pp. 225-238
    • Wiskerke, J.1    Pattij, T.2    Schoffelmeer, A.N.3    De Vries, T.J.4
  • 275
    • 0035824948 scopus 로고    scopus 로고
    • Cannabinoid CB1 receptor knockout mice fail to self-administer morphine but not other drugs of abuse
    • doi:10.1016/S0166-4328(00)00311-9
    • Cossu G, Ledent C, Fattore L, Imperato A, Bohme GA, Parmentier M, et al. Cannabinoid CB1 receptor knockout mice fail to self-administer morphine but not other drugs of abuse. Behav Brain Res (2001) 118:61-5. doi:10.1016/S0166-4328(00)00311-9.
    • (2001) Behav Brain Res , vol.118 , pp. 61-65
    • Cossu, G.1    Ledent, C.2    Fattore, L.3    Imperato, A.4    Bohme, G.A.5    Parmentier, M.6
  • 276
    • 84857125721 scopus 로고    scopus 로고
    • Cannabinoid receptor involvement in stress-induced cocaine reinstatement: potential interaction with noradrenergic pathways
    • doi:10.1016/j.neuroscience.2011.08.021
    • Vaughn LK, Mantsch JR, Vranjkovic O, Stroh G, Lacourt M, Kreutter M, et al. Cannabinoid receptor involvement in stress-induced cocaine reinstatement: potential interaction with noradrenergic pathways. Neuroscience (2012) 204:117-24. doi:10.1016/j.neuroscience.2011.08.021.
    • (2012) Neuroscience , vol.204 , pp. 117-124
    • Vaughn, L.K.1    Mantsch, J.R.2    Vranjkovic, O.3    Stroh, G.4    Lacourt, M.5    Kreutter, M.6
  • 277
    • 84857790066 scopus 로고    scopus 로고
    • The effects of cannabinoid CB1, CB2 and vanilloid TRPV1 receptor antagonists on cocaine addictive behavior in rats
    • doi:10.1016/j.brainres.2012.01.030
    • Adamczyk P, Miszkiel J, McCreary AC, Filip M, Papp M, Przegalinski E. The effects of cannabinoid CB1, CB2 and vanilloid TRPV1 receptor antagonists on cocaine addictive behavior in rats. Brain Res (2012) 1444:45-54. doi:10.1016/j.brainres.2012.01.030.
    • (2012) Brain Res , vol.1444 , pp. 45-54
    • Adamczyk, P.1    Miszkiel, J.2    McCreary, A.C.3    Filip, M.4    Papp, M.5    Przegalinski, E.6
  • 278
    • 0035986354 scopus 로고    scopus 로고
    • Inhibition of methamphetamine self-administration in rats by cannabinoid receptor antagonist AM 251
    • doi:10.1177/026988110201600204
    • Vinklerova J, Novakova J, Sulcova A. Inhibition of methamphetamine self-administration in rats by cannabinoid receptor antagonist AM 251. J Psychopharmacol (2002) 16:139-43. doi:10.1177/026988110201600204.
    • (2002) J Psychopharmacol , vol.16 , pp. 139-143
    • Vinklerova, J.1    Novakova, J.2    Sulcova, A.3
  • 279
    • 0033059089 scopus 로고    scopus 로고
    • Blockade of cannabinoid (CB1) receptors by 141716 selectively antagonizes drug-induced reinstatement of exploratory behaviour in gerbils
    • doi:10.1007/s002130050987
    • Poncelet M, Barnouin MC, Breliere JC, Le Fur G, Soubrie P. Blockade of cannabinoid (CB1) receptors by 141716 selectively antagonizes drug-induced reinstatement of exploratory behaviour in gerbils. Psychopharmacology (Berl) (1999) 144:144-50. doi:10.1007/s002130050987.
    • (1999) Psychopharmacology (Berl) , vol.144 , pp. 144-150
    • Poncelet, M.1    Barnouin, M.C.2    Breliere, J.C.3    Le Fur, G.4    Soubrie, P.5
  • 280
    • 0033773866 scopus 로고    scopus 로고
    • Self-administration behavior is maintained by the psychoactive ingredient of marijuana in squirrel monkeys
    • doi:10.1038/80577
    • Tanda G, Munzar P, Goldberg SR. Self-administration behavior is maintained by the psychoactive ingredient of marijuana in squirrel monkeys. Nat Neurosci (2000) 3:1073-4. doi:10.1038/80577.
    • (2000) Nat Neurosci , vol.3 , pp. 1073-1074
    • Tanda, G.1    Munzar, P.2    Goldberg, S.R.3
  • 281
    • 78149233989 scopus 로고    scopus 로고
    • Effects of cannabinoid CB(1) receptor antagonist rimonabant on acquisition and reinstatement of psychostimulant reward memory in mice
    • doi:10.1016/j.bbr.2010.10.008
    • Yu LL, Zhou SJ, Wang XY, Liu JF, Xue YX, Jiang W, et al. Effects of cannabinoid CB(1) receptor antagonist rimonabant on acquisition and reinstatement of psychostimulant reward memory in mice. Behav Brain Res (2011) 217:111-6. doi:10.1016/j.bbr.2010.10.008.
    • (2011) Behav Brain Res , vol.217 , pp. 111-116
    • Yu, L.L.1    Zhou, S.J.2    Wang, X.Y.3    Liu, J.F.4    Xue, Y.X.5    Jiang, W.6
  • 282
    • 70349850984 scopus 로고    scopus 로고
    • The CB1 antagonist rimonabant (SR141716) blocks cue-induced reinstatement of cocaine seeking and other context and extinction phenomena predictive of relapse
    • doi:10.1016/j.drugalcdep.2009.07.002
    • Ward SJ, Rosenberg M, Dykstra LA, Walker EA. The CB1 antagonist rimonabant (SR141716) blocks cue-induced reinstatement of cocaine seeking and other context and extinction phenomena predictive of relapse. Drug Alcohol Depend (2009) 105:248-55. doi:10.1016/j.drugalcdep.2009.07.002.
    • (2009) Drug Alcohol Depend , vol.105 , pp. 248-255
    • Ward, S.J.1    Rosenberg, M.2    Dykstra, L.A.3    Walker, E.A.4
  • 284
    • 65549155289 scopus 로고    scopus 로고
    • A role for the endocannabinoid system in the increased motivation for cocaine in extended-access conditions
    • doi:10.1523/JNEUROSCI.0563-09.2009
    • Orio L, Edwards S, George O, Parsons LH, Koob GF. A role for the endocannabinoid system in the increased motivation for cocaine in extended-access conditions. J Neurosci (2009) 29:4846-57. doi:10.1523/JNEUROSCI.0563-09.2009.
    • (2009) J Neurosci , vol.29 , pp. 4846-4857
    • Orio, L.1    Edwards, S.2    George, O.3    Parsons, L.H.4    Koob, G.F.5
  • 285
    • 80051582610 scopus 로고    scopus 로고
    • Acute blockade of CB1 receptor leads to reinstatement of MDMA-induced conditioned place preference
    • doi:10.1016/j.pbb.2011.07.011
    • Daza-Losada M, Minarro J, Aguilar MA, Valverde O, Rodriguez-Arias M. Acute blockade of CB1 receptor leads to reinstatement of MDMA-induced conditioned place preference. Pharmacol Biochem Behav (2011) 100:33-9. doi:10.1016/j.pbb.2011.07.011.
    • (2011) Pharmacol Biochem Behav , vol.100 , pp. 33-39
    • Daza-Losada, M.1    Minarro, J.2    Aguilar, M.A.3    Valverde, O.4    Rodriguez-Arias, M.5
  • 286
    • 73649118466 scopus 로고    scopus 로고
    • Effect of adolescent exposure to WIN 55212-2 on the acquisition and reinstatement of MDMA-induced conditioned place preference
    • doi:10.1016/j.pnpbp.2009.10.019
    • Rodriguez-Arias M, Manzanedo C, Roger-Sanchez C, Do Couto BR, Aguilar MA, Minarro J. Effect of adolescent exposure to WIN 55212-2 on the acquisition and reinstatement of MDMA-induced conditioned place preference. Prog Neuropsychopharmacol Biol Psychiatry (2010) 34:166-71. doi:10.1016/j.pnpbp.2009.10.019.
    • (2010) Prog Neuropsychopharmacol Biol Psychiatry , vol.34 , pp. 166-171
    • Rodriguez-Arias, M.1    Manzanedo, C.2    Roger-Sanchez, C.3    Do Couto, B.R.4    Aguilar, M.A.5    Minarro, J.6
  • 287
    • 11144316731 scopus 로고    scopus 로고
    • 3,4 Methylenedioxymethamphetamine-induced conditioned place preference (CPP) is mediated by endocannabinoid system
    • doi:10.1016/j.phrs.2004.07.009
    • Braida D, Iosue S, Pegorini S, Sala M. 3,4 Methylenedioxymethamphetamine-induced conditioned place preference (CPP) is mediated by endocannabinoid system. Pharmacol Res (2005) 51:177-82. doi:10.1016/j.phrs.2004.07.009.
    • (2005) Pharmacol Res , vol.51 , pp. 177-182
    • Braida, D.1    Iosue, S.2    Pegorini, S.3    Sala, M.4
  • 288
    • 0036688073 scopus 로고    scopus 로고
    • Role of the endocannabinoid system in MDMA intracerebral self-administration in rats
    • doi:10.1038/sj.bjp.0704825
    • Braida D, Sala M. Role of the endocannabinoid system in MDMA intracerebral self-administration in rats. Br J Pharmacol (2002) 136:1089-92. doi:10.1038/sj.bjp.0704825.
    • (2002) Br J Pharmacol , vol.136 , pp. 1089-1092
    • Braida, D.1    Sala, M.2
  • 289
    • 3242754258 scopus 로고    scopus 로고
    • Endocannabinoid system modulates relapse to methamphetamine seeking: possible mediation by the arachidonic acid cascade
    • doi:10.1038/sj.npp.1300454
    • Anggadiredja K, Nakamichi M, Hiranita T, Tanaka H, Shoyama Y, Watanabe S, et al. Endocannabinoid system modulates relapse to methamphetamine seeking: possible mediation by the arachidonic acid cascade. Neuropsychopharmacology (2004) 29:1470-8. doi:10.1038/sj.npp.1300454.
    • (2004) Neuropsychopharmacology , vol.29 , pp. 1470-1478
    • Anggadiredja, K.1    Nakamichi, M.2    Hiranita, T.3    Tanaka, H.4    Shoyama, Y.5    Watanabe, S.6
  • 290
    • 5444220592 scopus 로고    scopus 로고
    • Effect of low doses of delta9-tetrahydrocannabinol and cannabidiol on the extinction of cocaine-induced and amphetamine-induced conditioned place preference learning in rats
    • doi:10.1007/s00213-004-1825-7
    • Parker LA, Burton P, Sorge RE, Yakiwchuk C, Mechoulam R. Effect of low doses of delta9-tetrahydrocannabinol and cannabidiol on the extinction of cocaine-induced and amphetamine-induced conditioned place preference learning in rats. Psychopharmacology (Berl) (2004) 175:360-6. doi:10.1007/s00213-004-1825-7.
    • (2004) Psychopharmacology (Berl) , vol.175 , pp. 360-366
    • Parker, L.A.1    Burton, P.2    Sorge, R.E.3    Yakiwchuk, C.4    Mechoulam, R.5
  • 291
    • 39149143315 scopus 로고    scopus 로고
    • Augmented acquisition of cocaine self-administration and altered brain glucose metabolism in adult female but not male rats exposed to a cannabinoid agonist during adolescence
    • doi:10.1038/sj.npp.1301467
    • Higuera-Matas A, Soto-Montenegro ML, Del Olmo N, Miguens M, Torres I, Vaquero JJ, et al. Augmented acquisition of cocaine self-administration and altered brain glucose metabolism in adult female but not male rats exposed to a cannabinoid agonist during adolescence. Neuropsychopharmacology (2008) 33:806-13. doi:10.1038/sj.npp.1301467.
    • (2008) Neuropsychopharmacology , vol.33 , pp. 806-813
    • Higuera-Matas, A.1    Soto-Montenegro, M.L.2    Del Olmo, N.3    Miguens, M.4    Torres, I.5    Vaquero, J.J.6
  • 292
    • 0032586334 scopus 로고    scopus 로고
    • CB1 cannabinoid receptor agonist WIN 55,212-2 decreases intravenous cocaine self-administration in rats
    • doi:10.1016/S0166-4328(99)00059-5
    • Fattore L, Martellotta MC, Cossu G, Mascia MS, Fratta W. CB1 cannabinoid receptor agonist WIN 55,212-2 decreases intravenous cocaine self-administration in rats. Behav Brain Res (1999) 104:141-6. doi:10.1016/S0166-4328(99)00059-5.
    • (1999) Behav Brain Res , vol.104 , pp. 141-146
    • Fattore, L.1    Martellotta, M.C.2    Cossu, G.3    Mascia, M.S.4    Fratta, W.5
  • 293
    • 0033770664 scopus 로고    scopus 로고
    • Psychological stress, drug-related cues and cocaine craving
    • doi:10.1007/s002130000499
    • Sinha R, Fuse T, Aubin LR, O'Malley SS. Psychological stress, drug-related cues and cocaine craving. Psychopharmacology (Berl) (2000) 152:140-8. doi:10.1007/s002130000499.
    • (2000) Psychopharmacology (Berl) , vol.152 , pp. 140-148
    • Sinha, R.1    Fuse, T.2    Aubin, L.R.3    O'Malley, S.S.4
  • 294
    • 0017623057 scopus 로고
    • Delta9-THC as a discriminative cue in pigeons: effects of delta8-THC, CBD, and CBN
    • Jarbe TU, Henriksson BG, Ohlin GC. Delta9-THC as a discriminative cue in pigeons: effects of delta8-THC, CBD, and CBN. Arch Int Pharmacodyn Ther (1977) 228:68-72.
    • (1977) Arch Int Pharmacodyn Ther , vol.228 , pp. 68-72
    • Jarbe, T.U.1    Henriksson, B.G.2    Ohlin, G.C.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.