Inhibition of endocannabinoid catabolic enzymes elicits anxiolytic-like effects in the marble burying assay

Pharmacology Biochemistry and Behavior

Volumn 98, Issue 1, 2011, Pages 21-27

  Kinsey, Steven G ^a   O'Neal, Scott T ^a   Long, Jonathan Z ^b   Cravatt, Benjamin F ^b   Lichtman, Aron H ^a  

^a VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

^b SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

2 Arachidonoylglycerol; Anandamide; Anxiety; Endogenous cannabinoid; Fatty acid amide hydrolase; Marble burying; Monoacylglycerol lipase

Indexed keywords

ACYLGLYCEROL LIPASE; ANXIOLYTIC AGENT; CANNABINOID 1 RECEPTOR; DIAZEPAM; DRONABINOL; FATTY ACID AMIDASE; FATTY ACID AMIDASE INHIBITOR; JZL 184; PF 3845; RIMONABANT; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; DRUG EFFECT; ENZYME INHIBITION; LOCOMOTION; MALE; MOUSE; NONHUMAN; OBSESSIVE COMPULSIVE DISORDER; PRIORITY JOURNAL;

AMIDOHYDROLASES; ANIMALS; ANTI-ANXIETY AGENTS; ANXIETY DISORDERS; BENZODIOXOLES; DIAZEPAM; DISEASE MODELS, ANIMAL; ENDOCANNABINOIDS; ENZYME INHIBITORS; MALE; MICE; MICE, INBRED C57BL; MONOACYLGLYCEROL LIPASES; OBSESSIVE-COMPULSIVE DISORDER; PIPERIDINES; PYRAZOLES; RECEPTOR, CANNABINOID, CB1; TETRAHYDROCANNABINOL;

CANNABIS SATIVA;

EID: 78650619344     PISSN: 00913057     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.pbb.2010.12.002     Document Type: Article

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