Cardiac lipotoxicity: Molecular pathways and therapeutic implications

Current Heart Failure Reports

Volumn 10, Issue 2, 2013, Pages 109-121

  Drosatos, Konstantinos ^a   Schulze, P Christian ^b  

^a Columbia University ^*  (United States)

^b NewYork Presbyterian Hospital   (United States)

Author keywords

Apoptosis; Ceramide; Diacylglycerol; Endoplasmic reticulum stress; Fatty acid oxidation; Heart failure; Insulin signaling; Lipotoxicity; MAPK; PPAR; Protein kinase C

Indexed keywords

ACYL COENZYME A; ALBUMIN; CARNITINE PALMITOYLTRANSFERASE; CERAMIDE; CHYLOMICRON; COENZYME A; FATTY ACID; FATTY ACID TRANSPORTER; GLUCOSE TRANSPORTER 4; GLYCEROL; INSULIN; MALONYL COENZYME A; MITOGEN ACTIVATED PROTEIN KINASE; OCTANOIC ACID; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PHOSPHOLIPID; PROTEIN KINASE C; SPHINGOMYELIN PHOSPHODIESTERASE; TRIACYLGLYCEROL;

ADIPOSE TISSUE; APOPTOSIS; ARTICLE; CARDIOTOXICITY; CONGESTIVE CARDIOMYOPATHY; ENDOPLASMIC RETICULUM STRESS; ENERGY YIELD; ENZYME ACTIVATION; ENZYME SPECIFICITY; ESTERIFICATION; FATTY ACID TRANSPORT; GLUCOSE UTILIZATION; GLYCOLYSIS; HEART CONTRACTION; HEART VENTRICLE HYPERTROPHY; HYDROLYSIS; HYPERTENSION; HYPERTRIGLYCERIDEMIA; HYPOINSULINEMIA; INSULIN RESISTANCE; LIPID STORAGE; LIPOLYSIS; LIPOTOXICITY; NEGATIVE FEEDBACK; NONHUMAN;

APOPTOSIS; CARDIOMYOPATHIES; DIABETES COMPLICATIONS; FATTY ACIDS; HUMANS; LIPID METABOLISM; OBESITY; OXIDATION-REDUCTION;

EID: 84883054064     PISSN: 15469530     EISSN: 15469549     Source Type: Journal    
DOI: 10.1007/s11897-013-0133-0     Document Type: Article

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