-
1
-
-
0029828493
-
Insulin-like growth factor I and insulin induce adipogenic-related gene expression in fetal brown adipocyte primary cultures
-
Teruel T, Valverde AM, Benito M, Lorenzo M: Insulin-like growth factor I and insulin induce adipogenic-related gene expression in fetal brown adipocyte primary cultures. Biochem J 319:627-632, 1996
-
(1996)
Biochem J
, vol.319
, pp. 627-632
-
-
Teruel, T.1
Valverde, A.M.2
Benito, M.3
Lorenzo, M.4
-
2
-
-
0031836663
-
Inhibition of PI 3-kinase and RAS blocks IGF-I and insulin-induced uncoupling protein 1 gene expression in brown adipocytes
-
Teruel T, Valverde AM, Navarro P, Benito M, Lorenzo M: Inhibition of PI 3-kinase and RAS blocks IGF-I and insulin-induced uncoupling protein 1 gene expression in brown adipocytes. J Cell Physiol 176:99-109, 1998
-
(1998)
J Cell Physiol
, vol.176
, pp. 99-109
-
-
Teruel, T.1
Valverde, A.M.2
Navarro, P.3
Benito, M.4
Lorenzo, M.5
-
3
-
-
0032531221
-
Insulin/IGF-I rescues immortalized brown adipocytes from apoptosis down-regulating Bcl-xS expression, in a PI 3-kinase- and map kinase-dependent manner
-
Navarro P, Valverde AM, Benito M, Lorenzo M: Insulin/IGF-I rescues immortalized brown adipocytes from apoptosis down-regulating Bcl-xS expression, in a PI 3-kinase- and map kinase-dependent manner. Exp Cell Res 243:213-221, 1998
-
(1998)
Exp Cell Res
, vol.243
, pp. 213-221
-
-
Navarro, P.1
Valverde, A.M.2
Benito, M.3
Lorenzo, M.4
-
4
-
-
0033083488
-
Insulin and insulin-like growth factor I up-regulate GLUT4 gene expression in fetal brown adipocytes, in a phosphoinositide 3-kinase-dependent manner
-
Valverde AM, Navarro P, Teruel T, Conejo R, Benito M, Lorenzo M: Insulin and insulin-like growth factor I up-regulate GLUT4 gene expression in fetal brown adipocytes, in a phosphoinositide 3-kinase-dependent manner. Biochem J 337:397-405, 1999
-
(1999)
Biochem J
, vol.337
, pp. 397-405
-
-
Valverde, A.M.1
Navarro, P.2
Teruel, T.3
Conejo, R.4
Benito, M.5
Lorenzo, M.6
-
5
-
-
0033913213
-
Signaling pathways in insulin action: Molecular targets of insulin resistance
-
Pessin JE, Saltiel AR: Signaling pathways in insulin action: molecular targets of insulin resistance. J Clin Invest 106:165-169, 2000
-
(2000)
J Clin Invest
, vol.106
, pp. 165-169
-
-
Pessin, J.E.1
Saltiel, A.R.2
-
6
-
-
0029973135
-
Activated phosphatidylinositol 3-kinase is sufficient to mediate actin rearrangement and GLUT4 translocation in 3T3-L1 adipocytes
-
Martin SS, Haruta T, Morris AJ, Klippel A, Williams LT, Olefsky JM: Activated phosphatidylinositol 3-kinase is sufficient to mediate actin rearrangement and GLUT4 translocation in 3T3-L1 adipocytes. J Biol Chem 271:17605-17608, 1996
-
(1996)
J Biol Chem
, vol.271
, pp. 17605-17608
-
-
Martin, S.S.1
Haruta, T.2
Morris, A.J.3
Klippel, A.4
Williams, L.T.5
Olefsky, J.M.6
-
7
-
-
0029795178
-
Overexpression of a constitutively active form of phosphatidylinositol 3-kinase is sufficient to promote Glut 4 translocation in adipocytes
-
Tanti JF, Gremeaux T, Grillo S, Calleja V, Klippel A, Williams LT, Van Obberghen E, Le Marchand-Brustel Y: Overexpression of a constitutively active form of phosphatidylinositol 3-kinase is sufficient to promote Glut 4 translocation in adipocytes. J Biol Chem 271:25227-25232, 1996
-
(1996)
J Biol Chem
, vol.271
, pp. 25227-25232
-
-
Tanti, J.F.1
Gremeaux, T.2
Grillo, S.3
Calleja, V.4
Klippel, A.5
Williams, L.T.6
Van Obberghen, E.7
Le Marchand-Brustel, Y.8
-
8
-
-
0028308412
-
Phosphatidylinositol 3-kinase activation is required for insulin stimulation of pp70 S6 kinase, DNA synthesis, and glucose transporter translocation
-
Cheatham B, Vlahos CJ, Cheatham L, Wang L, Blenis J, Kahn CR: Phosphatidylinositol 3-kinase activation is required for insulin stimulation of pp70 S6 kinase, DNA synthesis, and glucose transporter translocation. Mol Cell Biol 14:4902-4911, 1994
-
(1994)
Mol Cell Biol
, vol.14
, pp. 4902-4911
-
-
Cheatham, B.1
Vlahos, C.J.2
Cheatham, L.3
Wang, L.4
Blenis, J.5
Kahn, C.R.6
-
9
-
-
0028875678
-
Insulin-stimulated GLUT4 translocation is mediated by a divergent intracellular signaling pathway
-
Haruta T, Morris AJ, Rose DW, Nelson JG, Mueckler M, Olefsky JM: Insulin-stimulated GLUT4 translocation is mediated by a divergent intracellular signaling pathway. J Biol Chem 270:27991-27994, 1995
-
(1995)
J Biol Chem
, vol.270
, pp. 27991-27994
-
-
Haruta, T.1
Morris, A.J.2
Rose, D.W.3
Nelson, J.G.4
Mueckler, M.5
Olefsky, J.M.6
-
10
-
-
0029908016
-
Expression of a constitutively active Akt Ser/Thr kinase in 3T3-L1 adipocytes stimulates glucose uptake and glucose transporter 4 translocation
-
Kohn AD, Summers SA, Birnbaum MJ, Roth RA: Expression of a constitutively active Akt Ser/Thr kinase in 3T3-L1 adipocytes stimulates glucose uptake and glucose transporter 4 translocation. J Biol Chem 271:31372-31378, 1996
-
(1996)
J Biol Chem
, vol.271
, pp. 31372-31378
-
-
Kohn, A.D.1
Summers, S.A.2
Birnbaum, M.J.3
Roth, R.A.4
-
11
-
-
0032496239
-
Construction and characterization of a conditionally active version of the serine/threonine kinase Akt
-
Kohn AD, Barthel A, Kovacina KS, Boge A, Wallach B, Summers SA, Birnbaum MJ, Scott PH, Lawrence JCJ, Roth RA: Construction and characterization of a conditionally active version of the serine/threonine kinase Akt. J Biol Chem 273:11937-11943, 1998
-
(1998)
J Biol Chem
, vol.273
, pp. 11937-11943
-
-
Kohn, A.D.1
Barthel, A.2
Kovacina, K.S.3
Boge, A.4
Wallach, B.5
Summers, S.A.6
Birnbaum, M.J.7
Scott, P.H.8
Lawrence, J.C.J.9
Roth, R.A.10
-
12
-
-
0034134245
-
Overexpression of wild-type Akt1 promoted insulin-stimulated p70S6 kinase (p70S6K) activity and affected GSK3 beta regulation, but did not promote insulin-stimulated GLUT4 translocation or glucose transport in L6 myotubes
-
Noda S, Kishi K, Yuasa T, Hayashi H, Ohnishi T, Miyata I, Nishitani H, Ebina Y: Overexpression of wild-type Akt1 promoted insulin-stimulated p70S6 kinase (p70S6K) activity and affected GSK3 beta regulation, but did not promote insulin-stimulated GLUT4 translocation or glucose transport in L6 myotubes. J Med Invest 47:47-55, 2000
-
(2000)
J Med Invest
, vol.47
, pp. 47-55
-
-
Noda, S.1
Kishi, K.2
Yuasa, T.3
Hayashi, H.4
Ohnishi, T.5
Miyata, I.6
Nishitani, H.7
Ebina, Y.8
-
13
-
-
0030734345
-
Physiological role of Akt in insulin-stimulated translocation of GLUT4 in transfected rat adipose cells
-
Cong LN, Chen H, Li Y, Zhou L, McGibbon MA, Taylor SI, Quon MJ: Physiological role of Akt in insulin-stimulated translocation of GLUT4 in transfected rat adipose cells. Mol Endocrinol 11:1881-1890, 1997
-
(1997)
Mol Endocrinol
, vol.11
, pp. 1881-1890
-
-
Cong, L.N.1
Chen, H.2
Li, Y.3
Zhou, L.4
McGibbon, M.A.5
Taylor, S.I.6
Quon, M.J.7
-
14
-
-
0031806103
-
Requirement for activation of the serine-threonine kinase Akt (protein kinase B) in insulin stimulation of protein synthesis but not of glucose transport
-
Kitamura T, Ogawa W, Sakaue H, Hino Y, Kuroda S, Takata M, Matsumoto M, Maeda T, Konishi H, Kikkawa U, Kasuga M: Requirement for activation of the serine-threonine kinase Akt (protein kinase B) in insulin stimulation of protein synthesis but not of glucose transport. Mol Cell Biol 18:3708-3717, 1998
-
(1998)
Mol Cell Biol
, vol.18
, pp. 3708-3717
-
-
Kitamura, T.1
Ogawa, W.2
Sakaue, H.3
Hino, Y.4
Kuroda, S.5
Takata, M.6
Matsumoto, M.7
Maeda, T.8
Konishi, H.9
Kikkawa, U.10
Kasuga, M.11
-
15
-
-
0033305091
-
Dependence of insulin-stimulated glucose transporter 4 translocation on 3-phosphoinositide-dependent protein kinase-1 and its target threonine-410 in the activation loop of protein kinase C-zeta
-
Bandyopadhyay G, Standaert ML, Sajan MP, Karnitz LM, Cong L, Quon MJ, Farese RV: Dependence of insulin-stimulated glucose transporter 4 translocation on 3-phosphoinositide-dependent protein kinase-1 and its target threonine-410 in the activation loop of protein kinase C-zeta. Mol Endocrinol 13:1766-1772, 1999
-
(1999)
Mol Endocrinol
, vol.13
, pp. 1766-1772
-
-
Bandyopadhyay, G.1
Standaert, M.L.2
Sajan, M.P.3
Karnitz, L.M.4
Cong, L.5
Quon, M.J.6
Farese, R.V.7
-
16
-
-
0031038052
-
Activation of protein kinase C (alpha, beta, and zeta) by insulin in 3T3/L1 cells: Transfection studies suggest a role for PKC-zeta in glucose transport
-
Bandyopadhyay G, Standaert ML, Zhao L, Yu B, Avignon A, Galloway L, Karnam P, Moscat J, Farese RV: Activation of protein kinase C (alpha, beta, and zeta) by insulin in 3T3/L1 cells: transfection studies suggest a role for PKC-zeta in glucose transport. J Biol Chem 272:2551-2558, 1997
-
(1997)
J Biol Chem
, vol.272
, pp. 2551-2558
-
-
Bandyopadhyay, G.1
Standaert, M.L.2
Zhao, L.3
Yu, B.4
Avignon, A.5
Galloway, L.6
Karnam, P.7
Moscat, J.8
Farese, R.V.9
-
17
-
-
0030982829
-
Phosphatidylinositol 3-kinase is a requirement for insulin-like growth factor I-induced differentiation, but not for mitogenesis, in fetal brown adipocytes
-
Valverde AM, Lorenzo M, Navarro P, Benito M: Phosphatidylinositol 3-kinase is a requirement for insulin-like growth factor I-induced differentiation, but not for mitogenesis, in fetal brown adipocytes. Mol Endocrinol 11:595-607, 1997
-
(1997)
Mol Endocrinol
, vol.11
, pp. 595-607
-
-
Valverde, A.M.1
Lorenzo, M.2
Navarro, P.3
Benito, M.4
-
18
-
-
0034696951
-
Okadaic acid inhibits insulin-induced glucose transport in fetal brown adipocytes in an Akt-independent and protein kinase C zeta-dependent manner
-
Valverde AM, Lorenzo M, Navarro P, Mur C, Benito M: Okadaic acid inhibits insulin-induced glucose transport in fetal brown adipocytes in an Akt-independent and protein kinase C zeta-dependent manner. FEBS Lett 472:153-158, 2000
-
(2000)
FEBS Lett
, vol.472
, pp. 153-158
-
-
Valverde, A.M.1
Lorenzo, M.2
Navarro, P.3
Mur, C.4
Benito, M.5
-
19
-
-
0035853447
-
Akt mediates insulin induction of glucose uptake and up-regulation of GLUT4 gene expression in brown adipocytes
-
Hernandez R, Teruel T, Lorenzo M: Akt mediates insulin induction of glucose uptake and up-regulation of GLUT4 gene expression in brown adipocytes. FEBS Lett 494:225-231, 2001
-
(2001)
FEBS Lett
, vol.494
, pp. 225-231
-
-
Hernandez, R.1
Teruel, T.2
Lorenzo, M.3
-
20
-
-
0027459878
-
Adipose expression of tumor necrosis factor-alpha: Direct role in obesity-linked insulin resistance
-
Hotamisligil GS, Shargill NS, Spiegelman BM: Adipose expression of tumor necrosis factor-alpha: direct role in obesity-linked insulin resistance. Science 259:87-91, 1993
-
(1993)
Science
, vol.259
, pp. 87-91
-
-
Hotamisligil, G.S.1
Shargill, N.S.2
Spiegelman, B.M.3
-
21
-
-
0032925340
-
Mechanisms of TNF-alpha-induced insulin resistance
-
Hotamisligil GS: Mechanisms of TNF-alpha-induced insulin resistance. Exp Clin Endocrinol Diabetes 107:119-125, 1999
-
(1999)
Exp Clin Endocrinol Diabetes
, vol.107
, pp. 119-125
-
-
Hotamisligil, G.S.1
-
22
-
-
0030756346
-
Protection from obesity-induced insulin resistance in mice lacking TNF-alpha function
-
Uysal KT, Wiesbrock SM, Marino MW, Hotamisligil GS: Protection from obesity-induced insulin resistance in mice lacking TNF-alpha function. Nature 389:610-614, 1997
-
(1997)
Nature
, vol.389
, pp. 610-614
-
-
Uysal, K.T.1
Wiesbrock, S.M.2
Marino, M.W.3
Hotamisligil, G.S.4
-
23
-
-
0028362194
-
Tumor necrosis factor alpha inhibits signaling from the insulin receptor
-
Hotamisligil GS, Murray DL, Choy LN, Spiegelman BM: Tumor necrosis factor alpha inhibits signaling from the insulin receptor. Proc Natl Acad Sci U S A 91:4854-4858, 1994
-
(1994)
Proc Natl Acad Sci U S A
, vol.91
, pp. 4854-4858
-
-
Hotamisligil, G.S.1
Murray, D.L.2
Choy, L.N.3
Spiegelman, B.M.4
-
24
-
-
0041009626
-
Tumor necrosis factor-α acutely inhibits insulin signaling in human adipocytes: Implication of the p80 tumor necrosis factor receptor
-
Liu LS, Spelleken M, Rohrig K, Hauner H, Eckel J: Tumor necrosis factor-α acutely inhibits insulin signaling in human adipocytes: implication of the p80 tumor necrosis factor receptor. Diabetes 47:515-522, 1998
-
(1998)
Diabetes
, vol.47
, pp. 515-522
-
-
Liu, L.S.1
Spelleken, M.2
Rohrig, K.3
Hauner, H.4
Eckel, J.5
-
25
-
-
0030061922
-
IRS-1-mediated inhibition of insulin receptor tyrosine kinase activity in TNF-alpha- and obesity-induced insulin resistance
-
Hotamisligil GS, Peraldi P, Budavari A, Ellis R, White MF, Spiegelman BM: IRS-1-mediated inhibition of insulin receptor tyrosine kinase activity in TNF-alpha- and obesity-induced insulin resistance. Science 271:665-668, 1996
-
(1996)
Science
, vol.271
, pp. 665-668
-
-
Hotamisligil, G.S.1
Peraldi, P.2
Budavari, A.3
Ellis, R.4
White, M.F.5
Spiegelman, B.M.6
-
26
-
-
0035144307
-
Insulin/IGF-1 and TNF-alpha stimulate phosphorylation of IRS-1 at inhibitory Ser307 via distinct pathways
-
Rui L, Aguirre V, Kim JK, Shulman GI, Lee A, Corbould A, Dunaif A, White MF: Insulin/IGF-1 and TNF-alpha stimulate phosphorylation of IRS-1 at inhibitory Ser307 via distinct pathways. J Clin Invest 107:181-189, 2001
-
(2001)
J Clin Invest
, vol.107
, pp. 181-189
-
-
Rui, L.1
Aguirre, V.2
Kim, J.K.3
Shulman, G.I.4
Lee, A.5
Corbould, A.6
Dunaif, A.7
White, M.F.8
-
27
-
-
0031793622
-
Tumor necrosis factor-alpha causes insulin receptor substrate-2-mediated insulin resistance and inhibits insulin-induced adipogenesis in fetal brown adipocytes
-
Valverde AM, Teruel T, Navarro P, Benito M, Lorenzo M: Tumor necrosis factor-alpha causes insulin receptor substrate-2-mediated insulin resistance and inhibits insulin-induced adipogenesis in fetal brown adipocytes. Endocrinology 139:1229-1238, 1998
-
(1998)
Endocrinology
, vol.139
, pp. 1229-1238
-
-
Valverde, A.M.1
Teruel, T.2
Navarro, P.3
Benito, M.4
Lorenzo, M.5
-
28
-
-
0028855405
-
Ceramide: An intracellular signal for apoptosis
-
Hannun YA, Obeid LM: Ceramide: an intracellular signal for apoptosis. Trends Biochem Sci 20:73-77, 1995
-
(1995)
Trends Biochem Sci
, vol.20
, pp. 73-77
-
-
Hannun, Y.A.1
Obeid, L.M.2
-
29
-
-
0031841949
-
Regulation of insulin-stimulated glucose transporter GLUT4 translocation and Akt kinase activity by ceramide
-
Summers SA, Garza LA, Zhou H, Birnbaum MJ: Regulation of insulin-stimulated glucose transporter GLUT4 translocation and Akt kinase activity by ceramide. Mol Cell Biol 18:5457-5464, 1998
-
(1998)
Mol Cell Biol
, vol.18
, pp. 5457-5464
-
-
Summers, S.A.1
Garza, L.A.2
Zhou, H.3
Birnbaum, M.J.4
-
30
-
-
0032569026
-
Inhibition of Akt kinase by cell-permeable ceramide and its implications for ceramide-induced apoptosis
-
Zhou H, Summers SA, Birnbaum MJ, Pittman RN: Inhibition of Akt kinase by cell-permeable ceramide and its implications for ceramide-induced apoptosis. J Biol Chem 273:16568-16575, 1998
-
(1998)
J Biol Chem
, vol.273
, pp. 16568-16575
-
-
Zhou, H.1
Summers, S.A.2
Birnbaum, M.J.3
Pittman, R.N.4
-
31
-
-
0033758144
-
Akt mediates insulin rescue from apoptosis in brown adipocytes: Effect of ceramide
-
Navarro P, Valverde AM, Rohn JL, Benito M, Lorenzo M: Akt mediates insulin rescue from apoptosis in brown adipocytes: effect of ceramide. Growth Horm IGF Res 10:256-266, 2000
-
(2000)
Growth Horm IGF Res
, vol.10
, pp. 256-266
-
-
Navarro, P.1
Valverde, A.M.2
Rohn, J.L.3
Benito, M.4
Lorenzo, M.5
-
32
-
-
0029160069
-
Protein kinase B (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction
-
Burgering BM, Coffer PJ: Protein kinase B (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction. Nature 376:599-602, 1995
-
(1995)
Nature
, vol.376
, pp. 599-602
-
-
Burgering, B.M.1
Coffer, P.J.2
-
33
-
-
0033588253
-
Ceramide generation is sufficient to account for the inhibition of the insulin-stimulated PKB pathway in C2C12 skeletal muscle cells pretreated with palmitate
-
Schmitz-Peiffer C, Craig DL, Biden TJ: Ceramide generation is sufficient to account for the inhibition of the insulin-stimulated PKB pathway in C2C12 skeletal muscle cells pretreated with palmitate. J Biol Chem 274:24202-24210, 1999
-
(1999)
J Biol Chem
, vol.274
, pp. 24202-24210
-
-
Schmitz-Peiffer, C.1
Craig, D.L.2
Biden, T.J.3
-
34
-
-
0017184389
-
A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
-
Bradford MM: A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 72:248-254, 1976
-
(1976)
Anal Biochem
, vol.72
, pp. 248-254
-
-
Bradford, M.M.1
-
35
-
-
0032577464
-
Association of the insulin receptor with phospholipase C-gamma (PLCgamma) in 3T3-L1 adipocytes suggests a role for PLCgamma in metabolic signaling by insulin
-
Kayali AG, Eichhorn J, Haruta T, Morris AJ, Nelson JG, Vollenweider P, Olefsky JM, Webster NJ: Association of the insulin receptor with phospholipase C-gamma (PLCgamma) in 3T3-L1 adipocytes suggests a role for PLCgamma in metabolic signaling by insulin. J Biol Chem 273:13808-13818, 1998
-
(1998)
J Biol Chem
, vol.273
, pp. 13808-13818
-
-
Kayali, A.G.1
Eichhorn, J.2
Haruta, T.3
Morris, A.J.4
Nelson, J.G.5
Vollenweider, P.6
Olefsky, J.M.7
Webster, N.J.8
-
36
-
-
0033575320
-
Ceramide induces Bc12 dephosphorylation via a mechanism involving mitochondrial PP2A
-
Ruvolo PP, Deng X, Ito T, Carr BK, May WS: Ceramide induces Bc12 dephosphorylation via a mechanism involving mitochondrial PP2A. J Biol Chem 274:20296-20300, 1999
-
(1999)
J Biol Chem
, vol.274
, pp. 20296-20300
-
-
Ruvolo, P.P.1
Deng, X.2
Ito, T.3
Carr, B.K.4
May, W.S.5
-
37
-
-
0031964986
-
Effects of cell-permeable ceramides and tumor necrosis factor-α on insulin signaling and glucose uptake in 3T3-L1 adipocytes
-
Wang CN, O'Brien L, Brindley DN: Effects of cell-permeable ceramides and tumor necrosis factor-α on insulin signaling and glucose uptake in 3T3-L1 adipocytes. Diabetes 47:24-31, 1998
-
(1998)
Diabetes
, vol.47
, pp. 24-31
-
-
Wang, C.N.1
O'Brien, L.2
Brindley, D.N.3
-
38
-
-
0034737436
-
Cross-talk between phosphatidylinositol 3-kinase and sphingomyelinase pathways as a mechanism for cell survival/death decisions
-
Burow ME, Weldon CB, Collins-Burow BM, Ramsey N, McKee A, Klippel A, McLachlan JA, Clejan S, Beckman BS: Cross-talk between phosphatidylinositol 3-kinase and sphingomyelinase pathways as a mechanism for cell survival/death decisions. J Biol Chem 275:9628-9635, 2000
-
(2000)
J Biol Chem
, vol.275
, pp. 9628-9635
-
-
Burow, M.E.1
Weldon, C.B.2
Collins-Burow, B.M.3
Ramsey, N.4
McKee, A.5
Klippel, A.6
McLachlan, J.A.7
Clejan, S.8
Beckman, B.S.9
-
39
-
-
0033965898
-
Caveolin 1-mediated regulation of receptor tyrosine kinase-associated phosphatidylinositol 3-kinase activity by ceramide
-
Zundel W, Swiersz LM, Giaccia A: Caveolin 1-mediated regulation of receptor tyrosine kinase-associated phosphatidylinositol 3-kinase activity by ceramide. Mol Cell Biol 20:1507-1514, 2000
-
(2000)
Mol Cell Biol
, vol.20
, pp. 1507-1514
-
-
Zundel, W.1
Swiersz, L.M.2
Giaccia, A.3
-
40
-
-
0342265155
-
Secretion of tumor necrosis factor-α shows a strong relationship to insulin-stimulated glucose transport in human adipose tissue
-
Lofgren P, van Harmelen V, Reynisdottir S, Naslund E, Ryden M, Rossner S, Amer P: Secretion of tumor necrosis factor-α shows a strong relationship to insulin-stimulated glucose transport in human adipose tissue. Diabetes 49:688-692, 2000
-
(2000)
Diabetes
, vol.49
, pp. 688-692
-
-
Lofgren, P.1
Van Harmelen, V.2
Reynisdottir, S.3
Naslund, E.4
Ryden, M.5
Rossner, S.6
Amer, P.7
-
41
-
-
0032787346
-
Signaling pathways mediating insulin-stimulated glucose transport
-
Summers SA, Yin VP, Whiteman EL, Garza LA, Cho H, Tuttle RL, Birnbaum MJ: Signaling pathways mediating insulin-stimulated glucose transport. Ann N Y Acad Sci 892:169-186, 1999
-
(1999)
Ann N Y Acad Sci
, vol.892
, pp. 169-186
-
-
Summers, S.A.1
Yin, V.P.2
Whiteman, E.L.3
Garza, L.A.4
Cho, H.5
Tuttle, R.L.6
Birnbaum, M.J.7
-
42
-
-
0033037484
-
Tumor necrosis factor-alpha and ceramides in insulin resistance
-
Brindley DN, Wang CN, Mei J, Xu J, Hanna AN: Tumor necrosis factor-alpha and ceramides in insulin resistance. Lipids 34 (Suppl.):S85-S88, 1999
-
(1999)
Lipids
, vol.34
, Issue.SUPPL.
-
-
Brindley, D.N.1
Wang, C.N.2
Mei, J.3
Xu, J.4
Hanna, A.N.5
-
43
-
-
0035957949
-
Insulin stimulates PKCzeta-mediated phosphorylation of insulin receptor substrate-1 (IRS-1): A self-attenuated mechanism to negatively regulate the function of IRS proteins
-
Liu YF, Paz K, Herschkovitz A, Alt A, Tennenbaum T, Sampson SR, Ohba M, Kuroki T, LeRoith D, Zick Y: Insulin stimulates PKCzeta-mediated phosphorylation of insulin receptor substrate-1 (IRS-1): a self-attenuated mechanism to negatively regulate the function of IRS proteins. J Biol Chem 276:14459-14465, 2001
-
(2001)
J Biol Chem
, vol.276
, pp. 14459-14465
-
-
Liu, Y.F.1
Paz, K.2
Herschkovitz, A.3
Alt, A.4
Tennenbaum, T.5
Sampson, S.R.6
Ohba, M.7
Kuroki, T.8
LeRoith, D.9
Zick, Y.10
-
44
-
-
0035793592
-
Protein kinase C-zeta phosphorylates insulin receptor substrate-1 and impairs its ability to activate phosphatidylinositol 3-kinase in response to insulin
-
Ravichandran LV, Esposito DL, Chen J, Quon MJ: Protein kinase C-zeta phosphorylates insulin receptor substrate-1 and impairs its ability to activate phosphatidylinositol 3-kinase in response to insulin. J Biol Chem 276:3543-3549, 2001
-
(2001)
J Biol Chem
, vol.276
, pp. 3543-3549
-
-
Ravichandran, L.V.1
Esposito, D.L.2
Chen, J.3
Quon, M.J.4
-
45
-
-
0029853098
-
Lipid mediators of insulin resistance: Ceramide signalling down-regulates GLUT4 gene transcription in 3T3-L1 adipocytes
-
Long SD, Pekala PH: Lipid mediators of insulin resistance: ceramide signalling down-regulates GLUT4 gene transcription in 3T3-L1 adipocytes. Biochem J 319:179-184, 1996
-
(1996)
Biochem J
, vol.319
, pp. 179-184
-
-
Long, S.D.1
Pekala, P.H.2
-
46
-
-
0033605420
-
Protein kinase Czeta is a negative regulator of protein kinase B activity
-
Doornbos RP, Theelen M, van der Hoeven PC, van Blitterswijk WJ, Verkleij AJ, van Bergen en Henegouwen PM: Protein kinase Czeta is a negative regulator of protein kinase B activity. J Biol Chem 274:8589-8596, 1999
-
(1999)
J Biol Chem
, vol.274
, pp. 8589-8596
-
-
Doornbos, R.P.1
Theelen, M.2
Van Der Hoeven, P.C.3
Van Blitterswijk, W.J.4
Verkleij, A.J.5
Van Bergen En Henegouwen, P.M.6
-
47
-
-
0032493105
-
Akt2 mRNA is highly expressed in embryonic brown fat and the AKT2 kinase is activated by insulin
-
Altomare DA, Lyons GE, Mitsuuchi Y, Cheng JQ, Testa JR: Akt2 mRNA is highly expressed in embryonic brown fat and the AKT2 kinase is activated by insulin. Oncogene 16:2407-2411, 1998
-
(1998)
Oncogene
, vol.16
, pp. 2407-2411
-
-
Altomare, D.A.1
Lyons, G.E.2
Mitsuuchi, Y.3
Cheng, J.Q.4
Testa, J.R.5
-
48
-
-
0034607914
-
Ceramide inhibits protein kinase B/Akt by promoting dephosphorylation of serine 473
-
Schubert KM, Scheid MP, Duronio V: Ceramide inhibits protein kinase B/Akt by promoting dephosphorylation of serine 473. J Biol Chem 275: 13330-13335, 2000
-
(2000)
J Biol Chem
, vol.275
, pp. 13330-13335
-
-
Schubert, K.M.1
Scheid, M.P.2
Duronio, V.3
-
49
-
-
0342980927
-
Inhibition of PKB/Akt1 by C2-ceramide involves activation of ceramide-activated protein phosphatase in PC12 cells
-
Salinas M, Lopez-Valdaliso R, Martin D, Alvarez A, Cuadrado A: Inhibition of PKB/Akt1 by C2-ceramide involves activation of ceramide-activated protein phosphatase in PC12 cells. Mol Cell Neurosci 15:156-169, 2000
-
(2000)
Mol Cell Neurosci
, vol.15
, pp. 156-169
-
-
Salinas, M.1
Lopez-Valdaliso, R.2
Martin, D.3
Alvarez, A.4
Cuadrado, A.5
-
50
-
-
0034816711
-
Ceramide induces the dephosphorylation and inhibition of constitutively activated Akt in PTEN negative U87mg cells
-
Zinda MJ, Vlahos CJ, Lai MT: Ceramide induces the dephosphorylation and inhibition of constitutively activated Akt in PTEN negative U87mg cells. Biochem Biophys Res Commun 280:1107-1115, 2001
-
(2001)
Biochem Biophys Res Commun
, vol.280
, pp. 1107-1115
-
-
Zinda, M.J.1
Vlahos, C.J.2
Lai, M.T.3
-
51
-
-
0033056079
-
Osmotic shock inhibits insulin signaling by maintaining Akt/protein kinase B in an inactive dephosphorylated state
-
Chen D, Fucini RV, Olson AL, Hemmings BA, Pessin JE: Osmotic shock inhibits insulin signaling by maintaining Akt/protein kinase B in an inactive dephosphorylated state. Mol Cell Biol 19:4684-4694, 1999
-
(1999)
Mol Cell Biol
, vol.19
, pp. 4684-4694
-
-
Chen, D.1
Fucini, R.V.2
Olson, A.L.3
Hemmings, B.A.4
Pessin, J.E.5
-
52
-
-
0032128301
-
Inhibition of the anti-apoptotic PI(3)K/Akt/Bad pathway by stress
-
Zundel W, Giaccia A: Inhibition of the anti-apoptotic PI(3)K/Akt/Bad pathway by stress. Genes Dev 12:1941-1946, 1998
-
(1998)
Genes Dev
, vol.12
, pp. 1941-1946
-
-
Zundel, W.1
Giaccia, A.2
-
53
-
-
0032478314
-
Fatty acid-induced beta cell apoptosis: A link between obesity and diabetes
-
Shimabukuro M, Zhou YT, Levi M, Unger RH: Fatty acid-induced beta cell apoptosis: a link between obesity and diabetes. Proc Natl Acad Sci U S A 95:2498-2502, 1998
-
(1998)
Proc Natl Acad Sci U S A
, vol.95
, pp. 2498-2502
-
-
Shimabukuro, M.1
Zhou, Y.T.2
Levi, M.3
Unger, R.H.4
|