Induction of cardiac angptl4 by dietary fatty acids is mediated by peroxisome proliferator-activated receptor β/δ and protects against fatty acid-induced oxidative stress

Circulation Research

Volumn 106, Issue 11, 2010, Pages 1712-1721

  Georgiadi, Anastasia ^a   Lichtenstein, Laeticia ^a,b   Degenhardt, Tatjana ^c   Boekschoten, Mark V ^a,b   Van Bilsen, Marc ^d   Desvergne, Beatrice ^e   Müller, Michael ^a,b   Kersten, Sander ^a,b  

^a WAGENINGEN UNIVERSITY   (Netherlands)

^b TOP INSTITUTE FOOD AND NUTRITION   (Netherlands)

^c UNIVERSITY OF EASTERN FINLAND   (Finland)

^d MAASTRICHT UNIVERSITY   (Netherlands)

^e UNIVERSITY OF LAUSANNE   (Switzerland)

Author keywords

Angptl4; Cardiac oxidative stress; Fatty acids; Gene expression; Peroxisome proliferator activated receptor

Indexed keywords

ANGIOPOIETIN RECEPTOR; LINOLENIC ACID; LIPOPROTEIN LIPASE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR DELTA; SMALL INTERFERING RNA; TRIACYLGLYCEROL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; FAT INTAKE; GENE EXPRESSION; GENETIC REGULATION; HEART MUSCLE CELL; LIPID PEROXIDATION; MALE; MOUSE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN FUNCTION; RECEPTOR UPREGULATION;

ALPHA-LINOLENIC ACID; ANGIOPOIETINS; ANIMALS; ANIMALS, NEWBORN; CARDIOMYOPATHIES; CELLS, CULTURED; CYTOPROTECTION; DIETARY FATS; FATTY ACIDS, UNSATURATED; FEEDBACK, PHYSIOLOGICAL; LINOLEIC ACID; LIPID PEROXIDATION; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MYOCARDIUM; OLEIC ACID; OXIDATIVE STRESS; PPAR DELTA; PPAR-BETA; RNA INTERFERENCE; TIME FACTORS; UP-REGULATION;

EID: 77953810264     PISSN: 00097330     EISSN: 15244571     Source Type: Journal    
DOI: 10.1161/CIRCRESAHA.110.217380     Document Type: Article

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