Cardiac-specific deletion of acetyl CoA carboxylase 2 prevents metabolic remodeling during pressure-overload hypertrophy

Circulation Research

Volumn 111, Issue 6, 2012, Pages 728-738

  Kolwicz, Stephen C ^a   Olson, David P ^b   Marney, Luke C ^a   Garcia Menendez, Lorena ^a   Synovec, Robert E ^a   Tian, Rong ^a  

^a UNIVERSITY OF WASHINGTON   (United States)

^b UNIVERSITY OF MICHIGAN SCHOOL OF PUBLIC HEALTH   (United States)

Author keywords

cardiac contractility and energetics; cardiac hypertrophy; cardiac metabolism; cardiovascular physiology; metabolism

Indexed keywords

ACETYL COENZYME A CARBOXYLASE; ACETYL COENZYME A CARBOXYLASE 2; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; AORTA CONSTRICTION; ARTICLE; CONTROLLED STUDY; DISEASE COURSE; ENERGY TRANSFER; FATTY ACID OXIDATION; GLYCOLYSIS; HEART LEFT VENTRICLE FUNCTION; HEART VENTRICLE HYPERTROPHY; MOUSE; NONHUMAN; OXYGEN CONSUMPTION; PHOSPHORUS NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL;

ACETYL-COA CARBOXYLASE; ANIMALS; AORTA; BLOTTING, WESTERN; CARDIOMEGALY; CARNITINE; CONSTRICTION, PATHOLOGIC; FATTY ACIDS; FEMALE; FIBROSIS; HEART; MALE; MALONYL COENZYME A; MICE; MICE, 129 STRAIN; MICE, INBRED C57BL; MICE, KNOCKOUT; MITOCHONDRIA, HEART; MYOCARDIUM; OXIDATION-REDUCTION; PRESSURE; VENTRICULAR REMODELING;

EID: 84865863479     PISSN: 00097330     EISSN: 15244571     Source Type: Journal    
DOI: 10.1161/CIRCRESAHA.112.268128     Document Type: Article

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