-
1
-
-
0026544517
-
Insulin stimulation of phosphatidylinositol 3-kinase activity maps to insulin receptor regions required for endogenous substrate phosphorylation
-
Backer J.M., Schroeder G.G., Kahn C.R., Myers Jr. M.G., Wilden P.A., Cahill D.A., and White M.F. Insulin stimulation of phosphatidylinositol 3-kinase activity maps to insulin receptor regions required for endogenous substrate phosphorylation. J. Biol. Chem. 267 (1992) 1367-1374
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 1367-1374
-
-
Backer, J.M.1
Schroeder, G.G.2
Kahn, C.R.3
Myers Jr., M.G.4
Wilden, P.A.5
Cahill, D.A.6
White, M.F.7
-
2
-
-
0026787592
-
The longitudinal effect of inhibiting fatty acid oxidation in diabetic rats fed a high fat diet
-
Barnett M., Collier G.R., and O'Dea K. The longitudinal effect of inhibiting fatty acid oxidation in diabetic rats fed a high fat diet. Horm. Metab. Res. 24 (1992) 360-362
-
(1992)
Horm. Metab. Res.
, vol.24
, pp. 360-362
-
-
Barnett, M.1
Collier, G.R.2
O'Dea, K.3
-
3
-
-
0036078412
-
Respiratory uncoupling lowers blood pressure through a leptin-dependent mechanism in genetically obese mice
-
Bernal-Mizrachi C., Weng S., Li B., Nolte L.A., Feng C., Coleman T., Holloszy J.O., and Semenkovich C.F. Respiratory uncoupling lowers blood pressure through a leptin-dependent mechanism in genetically obese mice. Arterioscler. Thromb. Vasc. Biol. 22 (2002) 961-968
-
(2002)
Arterioscler. Thromb. Vasc. Biol.
, vol.22
, pp. 961-968
-
-
Bernal-Mizrachi, C.1
Weng, S.2
Li, B.3
Nolte, L.A.4
Feng, C.5
Coleman, T.6
Holloszy, J.O.7
Semenkovich, C.F.8
-
4
-
-
0042967650
-
Dexamethasone induction of hypertension and diabetes is PPAR-α dependent in LDL receptor-null mice
-
Bernal-Mizrachi C., Weng S., Feng C., Finck B.N., Knutsen R.H., Leone T.C., Coleman T., Mecham R.P., Kelly D.P., and Semenkovich C.F. Dexamethasone induction of hypertension and diabetes is PPAR-α dependent in LDL receptor-null mice. Nat. Med. 9 (2003) 1069-1075
-
(2003)
Nat. Med.
, vol.9
, pp. 1069-1075
-
-
Bernal-Mizrachi, C.1
Weng, S.2
Feng, C.3
Finck, B.N.4
Knutsen, R.H.5
Leone, T.C.6
Coleman, T.7
Mecham, R.P.8
Kelly, D.P.9
Semenkovich, C.F.10
-
5
-
-
0347318052
-
The AMP-activated protein kinase cascade-a unifying system for energy control
-
Carling D. The AMP-activated protein kinase cascade-a unifying system for energy control. Trends Biochem. Sci. 29 (2004) 18-24
-
(2004)
Trends Biochem. Sci.
, vol.29
, pp. 18-24
-
-
Carling, D.1
-
6
-
-
0027390523
-
Effect of fatty acid oxidation inhibition on glucose metabolism in diabetic rats
-
Collier G.R., Traianedes K., Macaulay S.L., and O'Dea K. Effect of fatty acid oxidation inhibition on glucose metabolism in diabetic rats. Horm. Metab. Res. 25 (1993) 9-12
-
(1993)
Horm. Metab. Res.
, vol.25
, pp. 9-12
-
-
Collier, G.R.1
Traianedes, K.2
Macaulay, S.L.3
O'Dea, K.4
-
7
-
-
0029942339
-
Activation of a novel metabolic gene regulatory pathway by chronic stimulation of skeletal muscle
-
Cresci S., Wright L.D., Spratt J.A., Briggs F.N., and Kelly D.P. Activation of a novel metabolic gene regulatory pathway by chronic stimulation of skeletal muscle. Am. J. Physiol. 270 (1996) C1413-C1420
-
(1996)
Am. J. Physiol.
, vol.270
-
-
Cresci, S.1
Wright, L.D.2
Spratt, J.A.3
Briggs, F.N.4
Kelly, D.P.5
-
8
-
-
0026341780
-
Inhibition by salicylic acid of the activation and thus oxidation of long chain fatty acids. Possible role in the development of Reye's syndrome
-
Deschamps D., Fisch C., Fromenty B., Berson A., Degott C., and Pessayre D. Inhibition by salicylic acid of the activation and thus oxidation of long chain fatty acids. Possible role in the development of Reye's syndrome. J. Pharmacol. Exp. Ther. 259 (1991) 894-904
-
(1991)
J. Pharmacol. Exp. Ther.
, vol.259
, pp. 894-904
-
-
Deschamps, D.1
Fisch, C.2
Fromenty, B.3
Berson, A.4
Degott, C.5
Pessayre, D.6
-
9
-
-
0033305213
-
Peroxisome proliferator-activated receptors: Nuclear control of metabolism
-
Desvergne B., and Wahli W. Peroxisome proliferator-activated receptors: Nuclear control of metabolism. Endocr. Rev. 20 (1999) 649-688
-
(1999)
Endocr. Rev.
, vol.20
, pp. 649-688
-
-
Desvergne, B.1
Wahli, W.2
-
10
-
-
0032954778
-
Effects of free fatty acids on glucose transport and IRS-1-associated phosphatidylinositol 3-kinase activity
-
Dresner A., Laurent D., Marcucci M., Griffin M.E., Dufour S., Cline G.W., Slezak L.A., Andersen D.K., Hundal R.S., Rothman D.L., et al. Effects of free fatty acids on glucose transport and IRS-1-associated phosphatidylinositol 3-kinase activity. J. Clin. Invest. 103 (1999) 253-259
-
(1999)
J. Clin. Invest.
, vol.103
, pp. 253-259
-
-
Dresner, A.1
Laurent, D.2
Marcucci, M.3
Griffin, M.E.4
Dufour, S.5
Cline, G.W.6
Slezak, L.A.7
Andersen, D.K.8
Hundal, R.S.9
Rothman, D.L.10
-
11
-
-
2542504498
-
The evolving diabetes burden in the United States
-
Engelgau M.M., Geiss L.S., Saaddine J.B., Boyle J.P., Benjamin S.M., Gregg E.W., Tierney E.F., Rios-Burrows N., Mokdad A.H., Ford E.S., et al. The evolving diabetes burden in the United States. Ann. Intern. Med. 140 (2004) 945-950
-
(2004)
Ann. Intern. Med.
, vol.140
, pp. 945-950
-
-
Engelgau, M.M.1
Geiss, L.S.2
Saaddine, J.B.3
Boyle, J.P.4
Benjamin, S.M.5
Gregg, E.W.6
Tierney, E.F.7
Rios-Burrows, N.8
Mokdad, A.H.9
Ford, E.S.10
-
12
-
-
0036143320
-
The cardiac phenotype induced by PPARα overexpression mimics that caused by diabetes mellitus
-
Finck B., Lehman J.J., Leone T.C., Welch M.J., Bennett M.J., Kovacs A., Han X., Gross R.W., Kozak R., Lopaschuk G.D., and Kelly D.P. The cardiac phenotype induced by PPARα overexpression mimics that caused by diabetes mellitus. J. Clin. Invest. 109 (2002) 121-130
-
(2002)
J. Clin. Invest.
, vol.109
, pp. 121-130
-
-
Finck, B.1
Lehman, J.J.2
Leone, T.C.3
Welch, M.J.4
Bennett, M.J.5
Kovacs, A.6
Han, X.7
Gross, R.W.8
Kozak, R.9
Lopaschuk, G.D.10
Kelly, D.P.11
-
13
-
-
0037417725
-
A critical role for PPAR α-mediated lipotoxicity in the pathogenesis of diabetic cardiomyopathy: modulation of phenotype by dietary fat content
-
Finck B., Han X., Courtois M., Aimond F., Nerbonne J.M., Kovacs A., Gross R.W., and Kelly D.P. A critical role for PPAR α-mediated lipotoxicity in the pathogenesis of diabetic cardiomyopathy: modulation of phenotype by dietary fat content. Proc. Natl. Acad. Sci. USA 100 (2003) 1226-1231
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 1226-1231
-
-
Finck, B.1
Han, X.2
Courtois, M.3
Aimond, F.4
Nerbonne, J.M.5
Kovacs, A.6
Gross, R.W.7
Kelly, D.P.8
-
14
-
-
0345086474
-
Free fatty acid-induced insulin resistance is associated with activity of protein kinase C theta and alterations in the insulin signaling cascade
-
Griffin M.E., Marcucci M.J., Cline G.W., Bell K., Barucci N., Lee D., Goodyear L.J., Kraegen E.W., White M.F., and Shulman G.I. Free fatty acid-induced insulin resistance is associated with activity of protein kinase C theta and alterations in the insulin signaling cascade. Diabetes 48 (1999) 1270-1274
-
(1999)
Diabetes
, vol.48
, pp. 1270-1274
-
-
Griffin, M.E.1
Marcucci, M.J.2
Cline, G.W.3
Bell, K.4
Barucci, N.5
Lee, D.6
Goodyear, L.J.7
Kraegen, E.W.8
White, M.F.9
Shulman, G.I.10
-
15
-
-
0034595980
-
Peroxisome proliferator-activated receptor alpha activators improve insulin sensitivity and reduce adiposity
-
Guerre-Millo M., Gervois P., Raspe E., Madsen L., Poulain P., Derudas B., Herbert J.M., Winegar D.A., Willson T.M., Fruchart J.C., et al. Peroxisome proliferator-activated receptor alpha activators improve insulin sensitivity and reduce adiposity. J. Biol. Chem. 275 (2000) 16638-16642
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 16638-16642
-
-
Guerre-Millo, M.1
Gervois, P.2
Raspe, E.3
Madsen, L.4
Poulain, P.5
Derudas, B.6
Herbert, J.M.7
Winegar, D.A.8
Willson, T.M.9
Fruchart, J.C.10
-
16
-
-
0035653490
-
PPAR-alpha-null mice are protected from high-fat diet-induced insulin resistance
-
Guerre-Millo M., Rouault C., Poulain P., Andre J., Poitout V., Peters J.M., Gonzalez F.J., Fruchart J.C., Reach G., and Staels B. PPAR-alpha-null mice are protected from high-fat diet-induced insulin resistance. Diabetes 50 (2001) 2809-2814
-
(2001)
Diabetes
, vol.50
, pp. 2809-2814
-
-
Guerre-Millo, M.1
Rouault, C.2
Poulain, P.3
Andre, J.4
Poitout, V.5
Peters, J.M.6
Gonzalez, F.J.7
Fruchart, J.C.8
Reach, G.9
Staels, B.10
-
17
-
-
1442300773
-
UCP-mediated energy depletion in skeletal muscle increases glucose transport despite lipid accumulation and mitochondrial dysfunction
-
Han D.H., Nolte L.A., Ju J.S., Coleman T., Holloszy J.O., and Semenkovich C.F. UCP-mediated energy depletion in skeletal muscle increases glucose transport despite lipid accumulation and mitochondrial dysfunction. Am. J. Physiol. Endocrinol. Metab. 286 (2004) E347-E353
-
(2004)
Am. J. Physiol. Endocrinol. Metab.
, vol.286
-
-
Han, D.H.1
Nolte, L.A.2
Ju, J.S.3
Coleman, T.4
Holloszy, J.O.5
Semenkovich, C.F.6
-
18
-
-
0032540923
-
Dissociation of GLUT4 translocation and insulin-stimulated glucose transport in transgenic mice overexpressing GLUT1 in skeletal muscle
-
Hansen P.A., Wang W., Marshall B.A., Holloszy J.O., and Mueckler M. Dissociation of GLUT4 translocation and insulin-stimulated glucose transport in transgenic mice overexpressing GLUT1 in skeletal muscle. J. Biol. Chem. 273 (1998) 18173-18179
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 18173-18179
-
-
Hansen, P.A.1
Wang, W.2
Marshall, B.A.3
Holloszy, J.O.4
Mueckler, M.5
-
19
-
-
4744371376
-
ERRα directs PPARα signaling in the transcriptional control of energy metabolism in cardiac and skeletal muscle
-
Huss J.M., Pinéda Torra I., Staels B., Giguère V., and Kelly D.P. ERRα directs PPARα signaling in the transcriptional control of energy metabolism in cardiac and skeletal muscle. Mol. Cell. Biol. 24 (2004) 9079-9091
-
(2004)
Mol. Cell. Biol.
, vol.24
, pp. 9079-9091
-
-
Huss, J.M.1
Pinéda Torra, I.2
Staels, B.3
Giguère, V.4
Kelly, D.P.5
-
20
-
-
0842347859
-
Impaired expression of NADH dehydrogenase subunit 1 and PPARγ coactivator-1 in skeletal muscle of ZDF rats: restoration by troglitazone
-
Jové M., Salla J., Planavila A., Cabrero A., Michalik L., Wahli W., Laguna J.C., and Vázquez-Carrera M. Impaired expression of NADH dehydrogenase subunit 1 and PPARγ coactivator-1 in skeletal muscle of ZDF rats: restoration by troglitazone. J. Lipid Res. 45 (2004) 113-123
-
(2004)
J. Lipid Res.
, vol.45
, pp. 113-123
-
-
Jové, M.1
Salla, J.2
Planavila, A.3
Cabrero, A.4
Michalik, L.5
Wahli, W.6
Laguna, J.C.7
Vázquez-Carrera, M.8
-
21
-
-
0024837626
-
The tissue-specific expression and developmental regulation of the two nuclear genes encoding rat mitochondrial proteins: medium-chain acyl-CoA dehydrogenase and mitochondrial malate dehydrogenase
-
Kelly D.P., Gordon J.I., Alpers R., and Strauss A.W. The tissue-specific expression and developmental regulation of the two nuclear genes encoding rat mitochondrial proteins: medium-chain acyl-CoA dehydrogenase and mitochondrial malate dehydrogenase. J. Biol. Chem. 264 (1989) 18921-18925
-
(1989)
J. Biol. Chem.
, vol.264
, pp. 18921-18925
-
-
Kelly, D.P.1
Gordon, J.I.2
Alpers, R.3
Strauss, A.W.4
-
22
-
-
0032699670
-
Peroxisome proliferator-activated receptor α mediates the adaptive response to fasting
-
Kersten S., Seydoux J., Peters J.M., Gonzalez F.J., Desvergne B., and Wahli W. Peroxisome proliferator-activated receptor α mediates the adaptive response to fasting. J. Clin. Invest. 103 (1999) 1489-1498
-
(1999)
J. Clin. Invest.
, vol.103
, pp. 1489-1498
-
-
Kersten, S.1
Seydoux, J.2
Peters, J.M.3
Gonzalez, F.J.4
Desvergne, B.5
Wahli, W.6
-
23
-
-
0035912744
-
Tissue-specific overexpression of lipoprotein lipase causes tissue-specific insulin resistance
-
Kim J.K., Fillmore J.J., Chen Y., Yu C., Moore I.K., Pypaert M., Lutz E.P., Kako Y., Velez-Carrasco W., Goldberg I.J., et al. Tissue-specific overexpression of lipoprotein lipase causes tissue-specific insulin resistance. Proc. Natl. Acad. Sci. USA 98 (2001) 7522-7527
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 7522-7527
-
-
Kim, J.K.1
Fillmore, J.J.2
Chen, Y.3
Yu, C.4
Moore, I.K.5
Pypaert, M.6
Lutz, E.P.7
Kako, Y.8
Velez-Carrasco, W.9
Goldberg, I.J.10
-
24
-
-
0034903710
-
Prevention of fat-induced insulin resistance by salicylate
-
Kim J.K., Kim Y.J., Fillmore J.J., Chen Y., Moore I., Lee J., Yuan M., Li Z.W., Karin M., Perret P., et al. Prevention of fat-induced insulin resistance by salicylate. J. Clin. Invest. 108 (2001) 437-446
-
(2001)
J. Clin. Invest.
, vol.108
, pp. 437-446
-
-
Kim, J.K.1
Kim, Y.J.2
Fillmore, J.J.3
Chen, Y.4
Moore, I.5
Lee, J.6
Yuan, M.7
Li, Z.W.8
Karin, M.9
Perret, P.10
-
25
-
-
0038353634
-
Peroxisome proliferator-activated receptor-α agonist treatment in a transgenic model of type 2 diabetes reverses the lipotoxic state and improves glucose homeostasis
-
Kim H., Haluzik M., Asghar Z., Yau D., Joseph J.W., Fernandez A.M., Reitman M.L., Yakar S., Stannard B., Heron-Milhavet L., et al. Peroxisome proliferator-activated receptor-α agonist treatment in a transgenic model of type 2 diabetes reverses the lipotoxic state and improves glucose homeostasis. Diabetes 52 (2003) 1770-1778
-
(2003)
Diabetes
, vol.52
, pp. 1770-1778
-
-
Kim, H.1
Haluzik, M.2
Asghar, Z.3
Yau, D.4
Joseph, J.W.5
Fernandez, A.M.6
Reitman, M.L.7
Yakar, S.8
Stannard, B.9
Heron-Milhavet, L.10
-
26
-
-
0028997684
-
Targeted disruption of the α isoform of the peroxisome proliferator-activated receptor gene in mice results in abolishment of the pleiotropic effects of peroxisome proliferators
-
Lee S.S.T., Pineau T., Drago J., Lee E.J., Owens J.W., Kroetz D.L., Fernandez-Salguero P.M., Westphal H., and Gonzalez F.J. Targeted disruption of the α isoform of the peroxisome proliferator-activated receptor gene in mice results in abolishment of the pleiotropic effects of peroxisome proliferators. Mol. Cell. Biol. 15 (1995) 3012-3022
-
(1995)
Mol. Cell. Biol.
, vol.15
, pp. 3012-3022
-
-
Lee, S.S.T.1
Pineau, T.2
Drago, J.3
Lee, E.J.4
Owens, J.W.5
Kroetz, D.L.6
Fernandez-Salguero, P.M.7
Westphal, H.8
Gonzalez, F.J.9
-
27
-
-
0033594980
-
A critical role for the peroxisome proliferator-activated receptor alpha (PPARα) in the cellular fasting response: The PPARα -null mouse as a model of fatty acid oxidation disorders
-
Leone T.C., Weinheimer C.J., and Kelly D.P. A critical role for the peroxisome proliferator-activated receptor alpha (PPARα) in the cellular fasting response: The PPARα -null mouse as a model of fatty acid oxidation disorders. Proc. Natl. Acad. Sci. USA 96 (1999) 7473-7478
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 7473-7478
-
-
Leone, T.C.1
Weinheimer, C.J.2
Kelly, D.P.3
-
28
-
-
0027731309
-
Development of obesity in transgenic mice after genetic ablation of brown adipose tissue
-
Lowell B.B., Susulic V., Hamann A., Lawitts J.A., Himms-Hagen J., Boyer B.B., Kozak L.P., and Flier J.S. Development of obesity in transgenic mice after genetic ablation of brown adipose tissue. Nature 366 (1993) 740-742
-
(1993)
Nature
, vol.366
, pp. 740-742
-
-
Lowell, B.B.1
Susulic, V.2
Hamann, A.3
Lawitts, J.A.4
Himms-Hagen, J.5
Boyer, B.B.6
Kozak, L.P.7
Flier, J.S.8
-
29
-
-
0021172142
-
Mechanism of hyperglycemia and response to treatment with an inhibitor of fatty acid oxidation in a patient with insulin resistance due to antiinsulin receptor antibodies
-
Mandarino L., Tsalikian E., Bartold S., Marsh H., Carney A., Buerklin E., Tutwiler G., Haymond M., Handwerger B., and Rizza R. Mechanism of hyperglycemia and response to treatment with an inhibitor of fatty acid oxidation in a patient with insulin resistance due to antiinsulin receptor antibodies. J. Clin. Endocrinol. Metab. 59 (1984) 658-664
-
(1984)
J. Clin. Endocrinol. Metab.
, vol.59
, pp. 658-664
-
-
Mandarino, L.1
Tsalikian, E.2
Bartold, S.3
Marsh, H.4
Carney, A.5
Buerklin, E.6
Tutwiler, G.7
Haymond, M.8
Handwerger, B.9
Rizza, R.10
-
30
-
-
0035957375
-
Restoration of insulin-sensitive glucose transporter (GLUT4) gene expression in muscle cells by the transcriptional coactivator PGC-1
-
Michael L.F., Wu Z., Cheatham R.B., Puigserver P., Adelmant G., Lehman J.J., Kelly D.P., and Spiegelman B.M. Restoration of insulin-sensitive glucose transporter (GLUT4) gene expression in muscle cells by the transcriptional coactivator PGC-1. Proc. Natl. Acad. Sci. USA 98 (2001) 3820-3825
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 3820-3825
-
-
Michael, L.F.1
Wu, Z.2
Cheatham, R.B.3
Puigserver, P.4
Adelmant, G.5
Lehman, J.J.6
Kelly, D.P.7
Spiegelman, B.M.8
-
31
-
-
0038054341
-
PGC-1α-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes
-
Mootha V.K., Lindgren C.M., Eriksson K.-F., Subramanian A., Sihag S., Lehar J., Puigserver P., Carlsson E., Ridderstrale M., Laurila E., et al. PGC-1α-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes. Nat. Genet. 34 (2003) 267-273
-
(2003)
Nat. Genet.
, vol.34
, pp. 267-273
-
-
Mootha, V.K.1
Lindgren, C.M.2
Eriksson, K.-F.3
Subramanian, A.4
Sihag, S.5
Lehar, J.6
Puigserver, P.7
Carlsson, E.8
Ridderstrale, M.9
Laurila, E.10
-
32
-
-
0034717280
-
The MEF2A isoform is required for striated muscle-specific expression of the insulin-responsive GLUT4 glucose transporter
-
Mora S., and Pessin J.E. The MEF2A isoform is required for striated muscle-specific expression of the insulin-responsive GLUT4 glucose transporter. J. Biol. Chem. 275 (2000) 16323-16328
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 16323-16328
-
-
Mora, S.1
Pessin, J.E.2
-
33
-
-
0035050229
-
The MEF2A and MEF2D isoforms are differentially regulated in muscle and adipose tissue during states of insulin deficiency
-
Mora S., Yang C., Ryder J.W., Boeglin D., and Pessin J.E. The MEF2A and MEF2D isoforms are differentially regulated in muscle and adipose tissue during states of insulin deficiency. Endocrinology 142 (2001) 1999-2004
-
(2001)
Endocrinology
, vol.142
, pp. 1999-2004
-
-
Mora, S.1
Yang, C.2
Ryder, J.W.3
Boeglin, D.4
Pessin, J.E.5
-
34
-
-
2942702297
-
Role of calcium and AMP kinase in the regulation of mitochondrial biogenesis and GLUT4 levels in muscle
-
Ojuka E.O. Role of calcium and AMP kinase in the regulation of mitochondrial biogenesis and GLUT4 levels in muscle. Proc. Nutr. Soc. 63 (2004) 275-278
-
(2004)
Proc. Nutr. Soc.
, vol.63
, pp. 275-278
-
-
Ojuka, E.O.1
-
35
-
-
0037477855
-
Coordinated reduction of genes of oxidative metabolism in humans with insulin resistance and diabetes: potential role of PGC1 and NRF1
-
Patti M.E., Butte A.J., Crunkhorn S., Cusi K., Berria R., Kashyap S., Miyazaki Y., Kohane I., Costello M., Saccone R., et al. Coordinated reduction of genes of oxidative metabolism in humans with insulin resistance and diabetes: potential role of PGC1 and NRF1. Proc. Natl. Acad. Sci. USA 100 (2003) 8466-8471
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 8466-8471
-
-
Patti, M.E.1
Butte, A.J.2
Crunkhorn, S.3
Cusi, K.4
Berria, R.5
Kashyap, S.6
Miyazaki, Y.7
Kohane, I.8
Costello, M.9
Saccone, R.10
-
36
-
-
50549202600
-
The glucose fatty-acid cycle. Its role in insulin sensitivity and the metabolic disturbances of diabetes mellitus
-
Randle P.J., Hales C.N., and Garland P.B. The glucose fatty-acid cycle. Its role in insulin sensitivity and the metabolic disturbances of diabetes mellitus. Lancet 1 (1963) 785-789
-
(1963)
Lancet
, vol.1
, pp. 785-789
-
-
Randle, P.J.1
Hales, C.N.2
Garland, P.B.3
-
37
-
-
0035856949
-
Insulin signalling and the regulation of glucose and lipid metabolism
-
Saltiel A.R., and Kahn C.R. Insulin signalling and the regulation of glucose and lipid metabolism. Nature 414 (2001) 799-806
-
(2001)
Nature
, vol.414
, pp. 799-806
-
-
Saltiel, A.R.1
Kahn, C.R.2
-
38
-
-
3042802322
-
Malonyl-CoA decarboxylase (MCD) is differentially regulated in subcellular compartments by 5′ AMP-activated protein kinase (AMPK). Studies using H9c2 cells overexpressing MCD and AMPK by adenoviral gene trasfer technique
-
Sambandam N., Steinmetz M., Chu A., Altarejos J.Y., Dyck J.R., and Lopaschuk G.D. Malonyl-CoA decarboxylase (MCD) is differentially regulated in subcellular compartments by 5′ AMP-activated protein kinase (AMPK). Studies using H9c2 cells overexpressing MCD and AMPK by adenoviral gene trasfer technique. Eur. J. Biochem. 271 (2004) 2831-2840
-
(2004)
Eur. J. Biochem.
, vol.271
, pp. 2831-2840
-
-
Sambandam, N.1
Steinmetz, M.2
Chu, A.3
Altarejos, J.Y.4
Dyck, J.R.5
Lopaschuk, G.D.6
-
39
-
-
0033927667
-
Cellular mechanisms of insulin resistance
-
Shulman G.I. Cellular mechanisms of insulin resistance. J. Clin. Invest. 106 (2000) 171-176
-
(2000)
J. Clin. Invest.
, vol.106
, pp. 171-176
-
-
Shulman, G.I.1
-
40
-
-
0034744590
-
Peroxisome proliferator-activated receptor α deficiency reduces insulin resistance and atherosclerosis in apoE-null mice
-
Tordjman K., Bernal-Mizrachi C., Zemany L., Weng S., Feng C., Zhang F., Leone T.C., Coleman T., Kelly D.P., and Semenkovich C.F. Peroxisome proliferator-activated receptor α deficiency reduces insulin resistance and atherosclerosis in apoE-null mice. J. Clin. Invest. 107 (2001) 1025-1034
-
(2001)
J. Clin. Invest.
, vol.107
, pp. 1025-1034
-
-
Tordjman, K.1
Bernal-Mizrachi, C.2
Zemany, L.3
Weng, S.4
Feng, C.5
Zhang, F.6
Leone, T.C.7
Coleman, T.8
Kelly, D.P.9
Semenkovich, C.F.10
-
41
-
-
0018068529
-
Pharmacologic profile of methyl 2-tetradecylglycidate (McN-3716)-an orally effective hypoglycemic agent
-
Tutwiler G.F., Kirsch T., Mohrbacher R.J., and Ho W. Pharmacologic profile of methyl 2-tetradecylglycidate (McN-3716)-an orally effective hypoglycemic agent. Metabolism 10 (1978) 1539-1556
-
(1978)
Metabolism
, vol.10
, pp. 1539-1556
-
-
Tutwiler, G.F.1
Kirsch, T.2
Mohrbacher, R.J.3
Ho, W.4
-
42
-
-
8844276054
-
Regulation of muscle fiber type and running endurance by PPARdelta
-
10.1371/journal.pbio.0020294
-
Wang Y.-X., Zhang C.L., Yu R.T., Cho H.K., Nelson M.C., Bayuga-Ocampo C.R., Ham J., Kang H., and Evans R.M. Regulation of muscle fiber type and running endurance by PPARdelta. PLoS Biol. 2 (2004) e294 10.1371/journal.pbio.0020294
-
(2004)
PLoS Biol.
, vol.2
-
-
Wang, Y.-X.1
Zhang, C.L.2
Yu, R.T.3
Cho, H.K.4
Nelson, M.C.5
Bayuga-Ocampo, C.R.6
Ham, J.7
Kang, H.8
Evans, R.M.9
-
43
-
-
1442348164
-
Peroxisomal proliferator-activated receptor alpha deficiency diminishes insulin-responsiveness of gluconeogenic/glycolytic/pentose gene expression and substrate cycle flux
-
Xu J., Chang V., Joseph S.B., Trujillo C., Bassilian S., Saad M.F., Lee W.N., and Kurland I.J. Peroxisomal proliferator-activated receptor alpha deficiency diminishes insulin-responsiveness of gluconeogenic/glycolytic/pentose gene expression and substrate cycle flux. Endocrinology 145 (2004) 1087-1095
-
(2004)
Endocrinology
, vol.145
, pp. 1087-1095
-
-
Xu, J.1
Chang, V.2
Joseph, S.B.3
Trujillo, C.4
Bassilian, S.5
Saad, M.F.6
Lee, W.N.7
Kurland, I.J.8
-
44
-
-
0036679129
-
Coordinated patterns of gene expression for substrate and energy metabolism in skeletal muscle of diabetic mice
-
Yechoor V.K., Patti M.E., Saccone R., and Kahn C.R. Coordinated patterns of gene expression for substrate and energy metabolism in skeletal muscle of diabetic mice. Proc. Natl. Acad. Sci. USA 99 (2002) 10587-10592
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 10587-10592
-
-
Yechoor, V.K.1
Patti, M.E.2
Saccone, R.3
Kahn, C.R.4
-
45
-
-
0034773404
-
Role of AMP-activated protein kinase in mechanism of metformin action
-
Zhou G., Myers R., Li Y., Chen Y., Shen X., Fenyk-Melody J., Wu M., Ventre J., Doebber T., Fujii N., et al. Role of AMP-activated protein kinase in mechanism of metformin action. J. Clin. Invest. 108 (2001) 1167-1174
-
(2001)
J. Clin. Invest.
, vol.108
, pp. 1167-1174
-
-
Zhou, G.1
Myers, R.2
Li, Y.3
Chen, Y.4
Shen, X.5
Fenyk-Melody, J.6
Wu, M.7
Ventre, J.8
Doebber, T.9
Fujii, N.10
|