메뉴 건너뛰기




Volumn , Issue , 2007, Pages 89-114

Genetic and environmental factors in neurodegenerative diseases

Author keywords

[No Author keywords available]

Indexed keywords


EID: 84882552897     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1016/B978-044452809-4/50144-7     Document Type: Chapter
Times cited : (1)

References (163)
  • 1
    • 0034643888 scopus 로고    scopus 로고
    • The molecular and genetic basis of Alzheimer's disease: the end of the beginning
    • RN Rosenberg (2000) The molecular and genetic basis of Alzheimer's disease: the end of the beginning. Neurology 54 2045-2054.
    • (2000) Neurology , vol.54 , pp. 2045-2054
    • Rosenberg, R.N.1
  • 16
    • 0029809528 scopus 로고    scopus 로고
    • Amyotrophic lateral sclerosis: oxidative energy metabolism and calcium homeostasis in peripheral blood lymphocytes
    • D Curti, A Malaspina, G Facchetti, C Camana, L Mazzini, P Tosca, F Zerbi and M Ceroni (1996) Amyotrophic lateral sclerosis: oxidative energy metabolism and calcium homeostasis in peripheral blood lymphocytes. Neurology 47 1060-1064.
    • (1996) Neurology , vol.47 , pp. 1060-1064
    • Curti, D.1    Malaspina, A.2    Facchetti, G.3    Camana, C.4    Mazzini, L.5    Tosca, P.6    Zerbi, F.7    Ceroni, M.8
  • 18
    • 0042632880 scopus 로고    scopus 로고
    • Genetic epidemiology of amyotrophic lateral sclerosis
    • D Majoor-Krakauer, PJ Willems and A Hofman (2003) Genetic epidemiology of amyotrophic lateral sclerosis. Clin Genet. 63 83-101.
    • (2003) Clin Genet. , vol.63 , pp. 83-101
    • Majoor-Krakauer, D.1    Willems, P.J.2    Hofman, A.3
  • 24
    • 1642436839 scopus 로고    scopus 로고
    • Hereditary Creutzfeldt-Jakob disease and fatal familial insomnia
    • P Gambetti, P Parchi and SG Chen (2003) Hereditary Creutzfeldt-Jakob disease and fatal familial insomnia. Clin Lab Med. 23 43-64.
    • (2003) Clin Lab Med. , vol.23 , pp. 43-64
    • Gambetti, P.1    Parchi, P.2    Chen, S.G.3
  • 26
    • 0032829070 scopus 로고    scopus 로고
    • Evidence of active nerve cell degener-ation in the substantia nigra of humans years after 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine exposure
    • JW Langston, LS Forno, J Tetrud, AG Reeves, JA Kaplan and D Karluk (1999) Evidence of active nerve cell degener-ation in the substantia nigra of humans years after 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine exposure. Ann Neurol. 46 598-605.
    • (1999) Ann Neurol. , vol.46 , pp. 598-605
    • Langston, J.W.1    Forno, L.S.2    Tetrud, J.3    Reeves, A.G.4    Kaplan, J.A.5    Karluk, D.6
  • 27
    • 0036075892 scopus 로고    scopus 로고
    • Environmental risk factors and Parkinson's disease: selective degeneration of nigral dopaminergic neurons caused by the herbicide paraquat
    • AL McCormack, M Thiruchelvam, AB Manning-Bog, C Thiffault, JW Langston, DA Cory-Slechta and M.D.A. Di Monte DA (2002) Environmental risk factors and Parkinson's disease: selective degeneration of nigral dopaminergic neurons caused by the herbicide paraquat. Neurobiol Dis. 10 119-127.
    • (2002) Neurobiol Dis. , vol.10 , pp. 119-127
    • McCormack, A.L.1    Thiruchelvam, M.2    Manning-Bog, A.B.3    Thiffault, C.4    Langston, J.W.5    Cory-Slechta, D.A.6    Di, M.D.A.7
  • 28
    • 0037677549 scopus 로고    scopus 로고
    • Parkinson's disease and exposure to infectious agents and pesticides and the occurrence of brain injuries: role of neuroinflammation
    • B Liu, HM Gao and JS Hong (2003) Parkinson's disease and exposure to infectious agents and pesticides and the occurrence of brain injuries: role of neuroinflammation. Environ Health Perspect. 111 1065-1073.
    • (2003) Environ Health Perspect. , vol.111 , pp. 1065-1073
    • Liu, B.1    Gao, H.M.2    Hong, J.S.3
  • 29
    • 25844524877 scopus 로고    scopus 로고
    • Neurodegenerative diseases: an overview of environmental risk factors
    • RC Brown, AH Lockwood and BR Sonawane (2005) Neurodegenerative diseases: an overview of environmental risk factors. Environ Health Perspect. 113 1250-1256.
    • (2005) Environ Health Perspect. , vol.113 , pp. 1250-1256
    • Brown, R.C.1    Lockwood, A.H.2    Sonawane, B.R.3
  • 30
    • 0036714747 scopus 로고    scopus 로고
    • A meta-analysis of coffee drinking, cigarette smoking, and the risk of Parkinson's disease
    • MA Hernan, B Takkouche, F Caamano-Isorna and JJ Gestal-Otero (2002) A meta-analysis of coffee drinking, cigarette smoking, and the risk of Parkinson's disease. Ann Neurol. 52 276-284.
    • (2002) Ann Neurol. , vol.52 , pp. 276-284
    • Hernan, M.A.1    Takkouche, B.2    Caamano-Isorna, F.3    Gestal-Otero, J.J.4
  • 31
    • 0034035616 scopus 로고    scopus 로고
    • Metals and neuroscience
    • AI Bush (2000) Metals and neuroscience. Curr Opin Chem Biol. 4 184-191.
    • (2000) Curr Opin Chem Biol. , vol.4 , pp. 184-191
    • Bush, A.I.1
  • 32
    • 0031126991 scopus 로고    scopus 로고
    • Early manifestations of manganese neurotoxicity in humans: an update
    • D Mergler and M Baldwin (1997) Early manifestations of manganese neurotoxicity in humans: an update. Environ Res. 73 92-100.
    • (1997) Environ Res. , vol.73 , pp. 92-100
    • Mergler, D.1    Baldwin, M.2
  • 34
    • 0031843721 scopus 로고    scopus 로고
    • The risk of Parkinson's disease with exposure to pesticides, farming, well water, and rural living
    • JM Gorell, CC Johnson, BA Rybicki, EL Peterson and RJ Richardson (1998) The risk of Parkinson's disease with exposure to pesticides, farming, well water, and rural living. Neurology 50 1346-1350.
    • (1998) Neurology , vol.50 , pp. 1346-1350
    • Gorell, J.M.1    Johnson, C.C.2    Rybicki, B.A.3    Peterson, E.L.4    Richardson, R.J.5
  • 37
    • 0029940648 scopus 로고    scopus 로고
    • Risk for neuropathologically confirmed Alzheimer's disease and residual aluminum in municipal drinking water employing weighted residential histories
    • DR McLachlan, C Bergeron, JE Smith, D Boomer and SL Rifat (1996) Risk for neuropathologically confirmed Alzheimer's disease and residual aluminum in municipal drinking water employing weighted residential histories. Neurology 46 401-405.
    • (1996) Neurology , vol.46 , pp. 401-405
    • McLachlan, D.R.1    Bergeron, C.2    Smith, J.E.3    Boomer, D.4    Rifat, S.L.5
  • 38
    • 0030895548 scopus 로고    scopus 로고
    • Aluminum concentrations in drinking water and risk of Alzheimer's disease
    • CN Martyn, DN Coggon, H Inskip, RF Lacey and WF Young (1997) Aluminum concentrations in drinking water and risk of Alzheimer's disease. Epidemiology 8 281-286.
    • (1997) Epidemiology , vol.8 , pp. 281-286
    • Martyn, C.N.1    Coggon, D.N.2    Inskip, H.3    Lacey, R.F.4    Young, W.F.5
  • 40
    • 0031800225 scopus 로고    scopus 로고
    • Imbalances of trace elements related to oxidative damage in Alzheimer's disease brain
    • CR Cornett, WR Markesbery and WD Ehmann (1998) Imbalances of trace elements related to oxidative damage in Alzheimer's disease brain. Neurotoxicology 19 339-345.
    • (1998) Neurotoxicology , vol.19 , pp. 339-345
    • Cornett, C.R.1    Markesbery, W.R.2    Ehmann, W.D.3
  • 41
    • 2942729775 scopus 로고    scopus 로고
    • Metals in our minds: therapeutic implications for neurodegenerative disorders
    • PM Doraiswamy and AE Finefrock (2004) Metals in our minds: therapeutic implications for neurodegenerative disorders. Lancet Neurol. 3 431-434.
    • (2004) Lancet Neurol. , vol.3 , pp. 431-434
    • Doraiswamy, P.M.1    Finefrock, A.E.2
  • 42
  • 43
    • 1542616510 scopus 로고    scopus 로고
    • Traumatic brain injury as a risk factor for Alzheimer's disease
    • KA Jellinger (2004) Traumatic brain injury as a risk factor for Alzheimer's disease. J Neurol Neurosurg Psychiatry 75 511-512.
    • (2004) J Neurol Neurosurg Psychiatry , vol.75 , pp. 511-512
    • Jellinger, K.A.1
  • 45
    • 0026720427 scopus 로고
    • Content of the neurotoxins cycasin (methylazoxymethanol beta-D-glucoside) and BMAA (beta-N-methylamino-L-alanine) in cycad flour prepared by Guam Chamorros
    • GE Kisby, M Ellison and PS Spencer (1992) Content of the neurotoxins cycasin (methylazoxymethanol beta-D-glucoside) and BMAA (beta-N-methylamino-L-alanine) in cycad flour prepared by Guam Chamorros. Neurology 42 1336-1340.
    • (1992) Neurology , vol.42 , pp. 1336-1340
    • Kisby, G.E.1    Ellison, M.2    Spencer, P.S.3
  • 47
    • 3242748968 scopus 로고    scopus 로고
    • Molecular mediators, environmental modulators and experience-dependent synaptic dysfunction in Huntington's disease
    • AJ Hannan (2004) Molecular mediators, environmental modulators and experience-dependent synaptic dysfunction in Huntington's disease. Acta Biochim Pol. 51 415-430.
    • (2004) Acta Biochim Pol. , vol.51 , pp. 415-430
    • Hannan, A.J.1
  • 48
    • 0033608367 scopus 로고    scopus 로고
    • Surgical treatment and risk of sporadic Creutzfeldt-Jakob disease: a case-control study
    • S Collins, MG Law, A Fletcher, A Boyd, J Kaldor and CL Masters (1999) Surgical treatment and risk of sporadic Creutzfeldt-Jakob disease: a case-control study. Lancet 353 693-697.
    • (1999) Lancet , vol.353 , pp. 693-697
    • Collins, S.1    Law, M.G.2    Fletcher, A.3    Boyd, A.4    Kaldor, J.5    Masters, C.L.6
  • 50
    • 11044228082 scopus 로고    scopus 로고
    • Variant Creutzfeldt-Jakob disease: risk of transmission by blood and blood products
    • JW Ironside and MW Head (2004) Variant Creutzfeldt-Jakob disease: risk of transmission by blood and blood products. Haemophilia 10(Suppl. 4), 64-69.
    • (2004) Haemophilia , vol.10 , pp. 64-69
    • Ironside, J.W.1    Head, M.W.2
  • 52
    • 0025978557 scopus 로고
    • Risk of dementia in first-degree relatives of patients with Alzheimer's disease and related disorders
    • R Mayeux, M Sano, J Chen, T Tatemichi and Y Stern (1991) Risk of dementia in first-degree relatives of patients with Alzheimer's disease and related disorders. Arch Neurol. 48 269-273.
    • (1991) Arch Neurol. , vol.48 , pp. 269-273
    • Mayeux, R.1    Sano, M.2    Chen, J.3    Tatemichi, T.4    Stern, Y.5
  • 53
    • 0842347578 scopus 로고    scopus 로고
    • How heritable is Alzheimer's disease late in life? Findings from Swedish twins
    • NL Pedersen, M Gatz, S Berg and B Johansson (2004) How heritable is Alzheimer's disease late in life? Findings from Swedish twins. Ann Neurol. 55 180-185.
    • (2004) Ann Neurol. , vol.55 , pp. 180-185
    • Pedersen, N.L.1    Gatz, M.2    Berg, S.3    Johansson, B.4
  • 54
    • 0030823158 scopus 로고    scopus 로고
    • Effects of age sex ethnicity on the association between apolipoprotein E genotype and Alzheimer disease. A meta-analysis. APOE and Alzheimer Disease Meta Anal
    • LA Farrer, LA Cupples, JL Haines, B Hyman, WA Kukull, R Mayeux, RH Myers, MA Pericak-Vance, N Risch and CM Van Duijn (1997) Effects of age sex ethnicity on the association between apolipoprotein E genotype and Alzheimer disease. A meta-analysis. APOE and Alzheimer Disease Meta Anal. JAMA 278 1349-1356.
    • (1997) JAMA , vol.278 , pp. 1349-1356
    • Farrer, L.A.1    Cupples, L.A.2    Haines, J.L.3    Hyman, B.4    Kukull, W.A.5    Mayeux, R.6    Myers, R.H.7    Pericak-Vance, M.A.8    Risch, N.9    Van Duijn, C.M.10
  • 55
    • 17044380861 scopus 로고    scopus 로고
    • Genetic association analysis: lessons from the study of Alzheimers disease
    • AJ Brookes and JA Prince (2005) Genetic association analysis: lessons from the study of Alzheimers disease. Mutat Res. 573 152-159.
    • (2005) Mutat Res. , vol.573 , pp. 152-159
    • Brookes, A.J.1    Prince, J.A.2
  • 57
    • 4444302117 scopus 로고    scopus 로고
    • Molecular genetics of late-onset Alzheimer's disease
    • MI Kamboh (2004) Molecular genetics of late-onset Alzheimer's disease. Ann Hum Genet. 68 381-404.
    • (2004) Ann Hum Genet. , vol.68 , pp. 381-404
    • Kamboh, M.I.1
  • 58
    • 2942711631 scopus 로고    scopus 로고
    • APOE-[varepsilon]2 allele associated with higher prevalence of sporadic Parkinson disease
    • X Huang, PC Chen and C Poole (2004) APOE-[varepsilon]2 allele associated with higher prevalence of sporadic Parkinson disease. Neurology 62 2198-2202.
    • (2004) Neurology , vol.62 , pp. 2198-2202
    • Huang, X.1    Chen, P.C.2    Poole, C.3
  • 60
    • 20444504698 scopus 로고    scopus 로고
    • The genetic epidemiology of neurodegenerative disease
    • L Bertram and RE Tanzi (2005) The genetic epidemiology of neurodegenerative disease. J Clin Invest. 115 1449-1457.
    • (2005) J Clin Invest. , vol.115 , pp. 1449-1457
    • Bertram, L.1    Tanzi, R.E.2
  • 62
    • 33750917691 scopus 로고    scopus 로고
    • Is MTHFR polymorphism a risk factor for Alzheimer's disease like APOE?
    • LL Fernandez and RM Scheibe (2005) Is MTHFR polymorphism a risk factor for Alzheimer's disease like APOE? Arq Neuropsiquiatr. 63 1-6.
    • (2005) Arq Neuropsiquiatr. , vol.63 , pp. 1-6
    • Fernandez, L.L.1    Scheibe, R.M.2
  • 63
    • 4644234931 scopus 로고    scopus 로고
    • Association between the interleukin-1alpha gene and Alzheimer's disease: a meta-analysis
    • I Rainero, M Bo, M Ferrero, W Valfre, G Vaula and L Pinessi (2004) Association between the interleukin-1alpha gene and Alzheimer's disease: a meta-analysis. Neurobiol Aging 25 1293-1298.
    • (2004) Neurobiol Aging , vol.25 , pp. 1293-1298
    • Rainero, I.1    Bo, M.2    Ferrero, M.3    Valfre, W.4    Vaula, G.5    Pinessi, L.6
  • 64
    • 1342283131 scopus 로고    scopus 로고
    • Genetics and Parkinson's disease
    • DJ Cordato and DK Chan (2004) Genetics and Parkinson's disease. J Clin Neurosci. 11 119-123.
    • (2004) J Clin Neurosci. , vol.11 , pp. 119-123
    • Cordato, D.J.1    Chan, D.K.2
  • 65
    • 0032564134 scopus 로고    scopus 로고
    • Parkinson's disease, pesticides, and glutathione transferase polymorphisms
    • A Menegon, PG Board, AC Blackburn, GD Mellick and C.D.G. Le Couteur DG (1998) Parkinson's disease, pesticides, and glutathione transferase polymorphisms. Lancet 352 1344-1346.
    • (1998) Lancet , vol.352 , pp. 1344-1346
    • Menegon, A.1    Board, P.G.2    Blackburn, A.C.3    Mellick, G.D.4    Le, C.D.G.5
  • 66
    • 1842636254 scopus 로고    scopus 로고
    • The glutathione S-transferase polymorphisms in a control population and in Alzheimer's disease patients
    • I Zuntar, S Kalanj-Bognar, E Topic, R Petlevski, M Stefanovic and V Demarin (2004) The glutathione S-transferase polymorphisms in a control population and in Alzheimer's disease patients. Clin Chem Lab Med. 42 334-339.
    • (2004) Clin Chem Lab Med. , vol.42 , pp. 334-339
    • Zuntar, I.1    Kalanj-Bognar, S.2    Topic, E.3    Petlevski, R.4    Stefanovic, M.5    Demarin, V.6
  • 68
    • 20344369560 scopus 로고    scopus 로고
    • Increased glutathione S-transferase activity rescues dopaminergic neuron loss in a Drosophila model of Parkinson's disease
    • AJ Whitworth, DA Theodore, JC Greene, H Benes, PD Wes and LJ Pallanck (2005) Increased glutathione S-transferase activity rescues dopaminergic neuron loss in a Drosophila model of Parkinson's disease. Proc Natl Acad Sci USA 102 8024-8029.
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 8024-8029
    • Whitworth, A.J.1    Theodore, D.A.2    Greene, J.C.3    Benes, H.4    Wes, P.D.5    Pallanck, L.J.6
  • 71
    • 19444383616 scopus 로고    scopus 로고
    • Three SNPs in the GSTO1, GSTO2 and PRSS11 genes on chromosome 10 are not associated with age-at-onset of Alzheimer's disease
    • A Ozturk, PP Desai, RL Minster, ST Dekosky and MI Kamboh (2005) Three SNPs in the GSTO1, GSTO2 and PRSS11 genes on chromosome 10 are not associated with age-at-onset of Alzheimer's disease. Neurobiol Aging 26 1161-1165.
    • (2005) Neurobiol Aging , vol.26 , pp. 1161-1165
    • Ozturk, A.1    Desai, P.P.2    Minster, R.L.3    Dekosky, S.T.4    Kamboh, M.I.5
  • 72
    • 2542481935 scopus 로고    scopus 로고
    • Glutathione S-transferase omega 1 variation does not influence age at onset of Huntington's disease
    • L Arning, P Jagiello, S Wieczorek, C Saft, J Andrich and JT Epplen (2004) Glutathione S-transferase omega 1 variation does not influence age at onset of Huntington's disease. BMC Med Genet. 5 7.
    • (2004) BMC Med Genet. , vol.5 , pp. 7
    • Arning, L.1    Jagiello, P.2    Wieczorek, S.3    Saft, C.4    Andrich, J.5    Epplen, J.T.6
  • 74
    • 0032950492 scopus 로고    scopus 로고
    • N-acetyltransferase (NAT2) genotype and susceptibility of sporadic Alzheimer's disease
    • L Rocha, C Garcia, M.A. de Mendonca A, JP Gil, DT Bishop and MC Lechner (1999) N-acetyltransferase (NAT2) genotype and susceptibility of sporadic Alzheimer's disease. Pharmacogenetics 9 9-15.
    • (1999) Pharmacogenetics , vol.9 , pp. 9-15
    • Rocha, L.1    Garcia, C.2    de, M.A.3    Gil, J.P.4    Bishop, D.T.5    Lechner, M.C.6
  • 75
    • 2542482800 scopus 로고    scopus 로고
    • NAT gene polymorphisms and susceptibility to Alzheimer's disease: identification of a novel NAT1 allelic variant
    • N Johnson, P Bell, V Jonovska, M Budge and E Sim (2004.) NAT gene polymorphisms and susceptibility to Alzheimer's disease: identification of a novel NAT1 allelic variant. BMC Med Genet. 5 6.
    • (2004) BMC Med Genet. , vol.5 , pp. 6
    • Johnson, N.1    Bell, P.2    Jonovska, V.3    Budge, M.4    Sim, E.5
  • 76
    • 1042289665 scopus 로고    scopus 로고
    • Serotoninergic polymor-phisms (5-HTTLPR and 5-HT2A) : association studies with psychosis in Alzheimer disease
    • A Rocchi, D Micheli, R Ceravolo, ML Manca, G Tognoni, G Siciliano and L Murri (2003) Serotoninergic polymor-phisms (5-HTTLPR and 5-HT2A) : association studies with psychosis in Alzheimer disease. Genet Test. 7 309-314.
    • (2003) Genet Test. , vol.7 , pp. 309-314
    • Rocchi, A.1    Micheli, D.2    Ceravolo, R.3    Manca, M.L.4    Tognoni, G.5    Siciliano, G.6    Murri, L.7
  • 77
    • 4043174258 scopus 로고    scopus 로고
    • Association of the serotonin transporter and receptor gene polymorphisms in neuropsychiatric symptoms in Alzheimer disease
    • F Assal, M Alarcon, EC Solomon, D Masterman, DH Geschwind and JL Cummings (2004) Association of the serotonin transporter and receptor gene polymorphisms in neuropsychiatric symptoms in Alzheimer disease. Arch Neurol. 61 1249-1253.
    • (2004) Arch Neurol. , vol.61 , pp. 1249-1253
    • Assal, F.1    Alarcon, M.2    Solomon, E.C.3    Masterman, D.4    Geschwind, D.H.5    Cummings, J.L.6
  • 78
    • 0035936804 scopus 로고    scopus 로고
    • Amyotrophic lateral sclerosis. Unfolding the toxicity of the misfolded
    • JP Julien (2001) Amyotrophic lateral sclerosis. Unfolding the toxicity of the misfolded. Cell 104 581-591.
    • (2001) Cell , vol.104 , pp. 581-591
    • Julien, J.P.1
  • 81
    • 13644253800 scopus 로고    scopus 로고
    • Searching for the role and the most suitable biomarkers of oxidative stress in Alzheimer's disease and in other neurodegenerative diseases
    • L Migliore, I Fontana, R Colognato, F Coppedè, G Siciliano and L Murri (2005) Searching for the role and the most suitable biomarkers of oxidative stress in Alzheimer's disease and in other neurodegenerative diseases. Neurobiol Aging 26 587-595.
    • (2005) Neurobiol Aging , vol.26 , pp. 587-595
    • Migliore, L.1    Fontana, I.2    Colognato, R.3    Coppedè, F.4    Siciliano, G.5    Murri, L.6
  • 82
    • 27644485874 scopus 로고    scopus 로고
    • Oxidative stress in brain aging, neurodegenerative and vascular diseases: an overview
    • E Mariani, MC Polidori, A Cherubini and P Mecocci (2005) Oxidative stress in brain aging, neurodegenerative and vascular diseases: an overview. J Chromatogr B 827 65-75.
    • (2005) J Chromatogr B , vol.827 , pp. 65-75
    • Mariani, E.1    Polidori, M.C.2    Cherubini, A.3    Mecocci, P.4
  • 83
    • 0026666996 scopus 로고
    • Concepts of mild cognitive impairment in the elderly and their relationship to dementia: a review
    • B Dawe, A Procter and M Philpot (1992) Concepts of mild cognitive impairment in the elderly and their relationship to dementia: a review. Int J Geriatr Psychiatry 7 473-479.
    • (1992) Int J Geriatr Psychiatry , vol.7 , pp. 473-479
    • Dawe, B.1    Procter, A.2    Philpot, M.3
  • 86
    • 33744935554 scopus 로고    scopus 로고
    • Increased levels of 4-hydroxynonenal and acrolein, neurotoxic markers of lipid peroxidation, in the brain in mild cognitive impairment and early Alzheimer's d
    • TI Williams, BC Lynn, WR Markesbery and MA Lovell (2006) Increased levels of 4-hydroxynonenal and acrolein, neurotoxic markers of lipid peroxidation, in the brain in mild cognitive impairment and early Alzheimer's d. Neurobiol Aging 27 1094-1099.
    • (2006) Neurobiol Aging , vol.27 , pp. 1094-1099
    • Williams, T.I.1    Lynn, B.C.2    Markesbery, W.R.3    Lovell, M.A.4
  • 87
    • 33645106680 scopus 로고    scopus 로고
    • Increased oxidative damage in nuclear and mitochondrial DNA in mild cognitive impairment
    • J Wang, WR Markesbery and MA Lovell (2006) Increased oxidative damage in nuclear and mitochondrial DNA in mild cognitive impairment. J Neurochem. 96 825-832.
    • (2006) J Neurochem. , vol.96 , pp. 825-832
    • Wang, J.1    Markesbery, W.R.2    Lovell, M.A.3
  • 89
    • 27644446857 scopus 로고    scopus 로고
    • Lipid peroxidation is an early event in the brain in amnestic mild cognitive impairment
    • WR Markesbery, RJ Kryscio, MA Lovell and JD Morrow (2005) Lipid peroxidation is an early event in the brain in amnestic mild cognitive impairment. Ann Neurol. 58 730-735.
    • (2005) Ann Neurol. , vol.58 , pp. 730-735
    • Markesbery, W.R.1    Kryscio, R.J.2    Lovell, M.A.3    Morrow, J.D.4
  • 90
  • 91
    • 0034834620 scopus 로고    scopus 로고
    • Increased oxidative stress in Alzheimer's disease as assessed with 4-hydroxynonenal but not malondialdehyde
    • LT McGrath, BM McGleenon, S Brennan, D McColl, S McILroy and AP Passmore (2001) Increased oxidative stress in Alzheimer's disease as assessed with 4-hydroxynonenal but not malondialdehyde. QJM 94 485-490.
    • (2001) QJM , vol.94 , pp. 485-490
    • McGrath, L.T.1    McGleenon, B.M.2    Brennan, S.3    McColl, D.4    McILroy, S.5    Passmore, A.P.6
  • 92
    • 0036224435 scopus 로고    scopus 로고
    • The effect of increased concentrations of homocysteine on the concentration of (E) -4-hydroxy-2-nonenal in the plasma and cerebrospinal fluid of patients with
    • ML Selley, DR Close and SE Stern (2002) The effect of increased concentrations of homocysteine on the concentration of (E) -4-hydroxy-2-nonenal in the plasma and cerebrospinal fluid of patients with. Neurobiol Aging 23 383-388.
    • (2002) Neurobiol Aging , vol.23 , pp. 383-388
    • Selley, M.L.1    Close, D.R.2    Stern, S.E.3
  • 94
    • 33747687207 scopus 로고    scopus 로고
    • Plasma F2-isoprostane levels are increased in Alzheimer's disease: evidence of increased oxidative stress in vivo
    • E Waddington, K Croft, R Clarnette and R Artins (1999) Plasma F2-isoprostane levels are increased in Alzheimer's disease: evidence of increased oxidative stress in vivo. Alzheimers' Rep. 2 227-282.
    • (1999) Alzheimers' Rep. , vol.2 , pp. 227-282
    • Waddington, E.1    Croft, K.2    Clarnette, R.3    Artins, R.4
  • 95
    • 0035867047 scopus 로고    scopus 로고
    • Sign of lipid peroxidation as measured in the urine of patients with probable Alzheimer's disease
    • EE Tuppo, LJ Forman, BW Spur, RE Cheng-Ting, A Chopra and A Cavalieri (2001) Sign of lipid peroxidation as measured in the urine of patients with probable Alzheimer's disease. Brain Res Bull. 54 565-568.
    • (2001) Brain Res Bull. , vol.54 , pp. 565-568
    • Tuppo, E.E.1    Forman, L.J.2    Spur, B.W.3    Cheng-Ting, R.E.4    Chopra, A.5    Cavalieri, A.6
  • 96
    • 0033762711 scopus 로고    scopus 로고
    • Increased 8, 12-iso-iPF (2 alpha) -IV in Alzheimer's disease: correlation of specific noninvasive index of lipid peroxidation with disease severity
    • D Praticò, C Clark, VM Lee, JQ Trojanowski, J Rokach and GA Fitzgerald (2000) Increased 8, 12-iso-iPF (2 alpha) -IV in Alzheimer's disease: correlation of specific noninvasive index of lipid peroxidation with disease severity. Ann Neurol. 48 809-812.
    • (2000) Ann Neurol. , vol.48 , pp. 809-812
    • Praticò, D.1    Clark, C.2    Lee, V.M.3    Trojanowski, J.Q.4    Rokach, J.5    Fitzgerald, G.A.6
  • 102
    • 4544225426 scopus 로고    scopus 로고
    • Detection of oxidative DNA damage in lymphocytes of patients with Alzheimer's disease
    • E Kadioglu, S Sardas, S Aslan, E Isik and K.A. Esat Karakaya A (2004) Detection of oxidative DNA damage in lymphocytes of patients with Alzheimer's disease. Biomarkers 9 203-209.
    • (2004) Biomarkers , vol.9 , pp. 203-209
    • Kadioglu, E.1    Sardas, S.2    Aslan, S.3    Isik, E.4    Esat, K.A.5
  • 105
    • 0032786731 scopus 로고    scopus 로고
    • Oxidative stress indicators are elevated in de novo Parkinson's disease patients
    • TV Ilic, M Jovanovic, A Jovicic and M Tomovic (1999) Oxidative stress indicators are elevated in de novo Parkinson's disease patients. Funct Neurol. 14 141-147.
    • (1999) Funct Neurol. , vol.14 , pp. 141-147
    • Ilic, T.V.1    Jovanovic, M.2    Jovicic, A.3    Tomovic, M.4
  • 106
    • 0026728880 scopus 로고
    • Oxygen free radical producing activity of polymorphonuclear leukocytes in patients with Parkinson's disease
    • J Kalra, AH Rajput, SV Mantha, AK Chaudhary and K Prasad (1992) Oxygen free radical producing activity of polymorphonuclear leukocytes in patients with Parkinson's disease. Mol Cell Biochem. 112 181-186.
    • (1992) Mol Cell Biochem. , vol.112 , pp. 181-186
    • Kalra, J.1    Rajput, A.H.2    Mantha, S.V.3    Chaudhary, A.K.4    Prasad, K.5
  • 107
    • 0034750776 scopus 로고    scopus 로고
    • Parkinson's disease is associated with oxidative stress: comparison of peripheral antioxidant profiles in living Parkinson's, Alzheimer's and vascular dementi
    • JA Serra, RO Dominguez, L.E.S. de Lustig ES, EM Guareschi, AL Famulari, EL Bartolome and ER Marschoff (2001) Parkinson's disease is associated with oxidative stress: comparison of peripheral antioxidant profiles in living Parkinson's, Alzheimer's and vascular dementi. J Neural Transm. 108 1135-1148.
    • (2001) J Neural Transm. , vol.108 , pp. 1135-1148
    • Serra, J.A.1    Dominguez, R.O.2    de, L.E.S.3    Guareschi, E.M.4    Famulari, A.L.5    Bartolome, E.L.6    Marschoff, E.R.7
  • 109
    • 0032852976 scopus 로고    scopus 로고
    • Determination of hydroxyl free radical forma-tion in human platelets using high-performance liquid chromatography with electrochemical detection
    • F Blandini, E Martignoni, R Ricotti, J.F. di Jeso F and G Nappi (2005) Determination of hydroxyl free radical forma-tion in human platelets using high-performance liquid chromatography with electrochemical detection. J Chromatogr B Biomed Sci Appl. 732 213-220.
    • (2005) J Chromatogr B Biomed Sci Appl. , vol.732 , pp. 213-220
    • Blandini, F.1    Martignoni, E.2    Ricotti, R.3    di, J.F.4    Nappi, G.5
  • 112
    • 0033009113 scopus 로고    scopus 로고
    • Remarkable increase in cerebrospinal fluid 3-nitrotyrosine in patients with sporadic amyotrophic lateral sclerosis
    • H Tohgi, T Abe, K Yamazaki, T Murata, E Ishizaki and C Isobe (1999) Remarkable increase in cerebrospinal fluid 3-nitrotyrosine in patients with sporadic amyotrophic lateral sclerosis. Ann Neurol. 46 129-131.
    • (1999) Ann Neurol. , vol.46 , pp. 129-131
    • Tohgi, H.1    Abe, T.2    Yamazaki, K.3    Murata, T.4    Ishizaki, E.5    Isobe, C.6
  • 113
    • 0031722955 scopus 로고    scopus 로고
    • Presence of 4-hydroxynonenal in cerebrospinal fluid of patients with sporadic amyotrophic lateral sclerosis
    • RG Smith, YK Henry, MP Mattson and SH Appel (1998) Presence of 4-hydroxynonenal in cerebrospinal fluid of patients with sporadic amyotrophic lateral sclerosis. Ann Neurol. 44 696-699.
    • (1998) Ann Neurol. , vol.44 , pp. 696-699
    • Smith, R.G.1    Henry, Y.K.2    Mattson, M.P.3    Appel, S.H.4
  • 114
    • 2442701519 scopus 로고    scopus 로고
    • Increased lipid peroxidation in sera of ALS patients: a potential biomarker of disease burden
    • EP Simpson, YK Henry, JS Henkel, RG Smith and SH Appel (2004) Increased lipid peroxidation in sera of ALS patients: a potential biomarker of disease burden. Neurology 62 1758-1765.
    • (2004) Neurology , vol.62 , pp. 1758-1765
    • Simpson, E.P.1    Henry, Y.K.2    Henkel, J.S.3    Smith, R.G.4    Appel, S.H.5
  • 116
    • 0028788091 scopus 로고
    • Superoxide dismutase and free radicals in sporadic amyotrophic lateral sclerosis: relationship to clinical data
    • Y Ihara, A Mori, T Hayabara, M Kawai, R Namba, K Nobukuni, K Sato and M Kibata (1995) Superoxide dismutase and free radicals in sporadic amyotrophic lateral sclerosis: relationship to clinical data. J Neurol Sci. 134 51-56.
    • (1995) J Neurol Sci. , vol.134 , pp. 51-56
    • Ihara, Y.1    Mori, A.2    Hayabara, T.3    Kawai, M.4    Namba, R.5    Nobukuni, K.6    Sato, K.7    Kibata, M.8
  • 119
    • 0030968429 scopus 로고    scopus 로고
    • Evaluation of antioxidants, pro-tein, and lipid oxidation products in blood from sporadic amyotrophic lateral sclerosis patients
    • PI Oteiza, OD Uchitel, F Carrasquedo, AL Dubrovski, JC Roma and CG Fraga (1997) Evaluation of antioxidants, pro-tein, and lipid oxidation products in blood from sporadic amyotrophic lateral sclerosis patients. Neurochem Res. 22 535-539.
    • (1997) Neurochem Res. , vol.22 , pp. 535-539
    • Oteiza, P.I.1    Uchitel, O.D.2    Carrasquedo, F.3    Dubrovski, A.L.4    Roma, J.C.5    Fraga, C.G.6
  • 121
    • 1842505677 scopus 로고    scopus 로고
    • Proteomics: a new approach to investigate oxidative stress in Alzheimer's disease brain
    • DA Butterfield (2004) Proteomics: a new approach to investigate oxidative stress in Alzheimer's disease brain. Brain Res. 1000 1-7.
    • (2004) Brain Res. , vol.1000 , pp. 1-7
    • Butterfield, D.A.1
  • 122
    • 4444239787 scopus 로고    scopus 로고
    • Proteomic approach to studying Parkinson's disease
    • J Zhang and DR Goodlett (2004) Proteomic approach to studying Parkinson's disease. Mol Neurobiol. 29 271-288.
    • (2004) Mol Neurobiol. , vol.29 , pp. 271-288
    • Zhang, J.1    Goodlett, D.R.2
  • 124
    • 27144494994 scopus 로고    scopus 로고
    • Ribosome dysfunction is an early event in Alzheimer's disease
    • Q Ding, WR Markesbery, Q Chen, F Li and JN Keller (2005) Ribosome dysfunction is an early event in Alzheimer's disease. J Neurosci. 25 9171-9175.
    • (2005) J Neurosci. , vol.25 , pp. 9171-9175
    • Ding, Q.1    Markesbery, W.R.2    Chen, Q.3    Li, F.4    Keller, J.N.5
  • 125
    • 0036224783 scopus 로고    scopus 로고
    • The potential role of aluminium in Alzheimer's disease
    • A Campbell (2002) The potential role of aluminium in Alzheimer's disease. Nephrol Dial Transplant. 2 17-20.
    • (2002) Nephrol Dial Transplant. , vol.2 , pp. 17-20
    • Campbell, A.1
  • 126
    • 0347134484 scopus 로고    scopus 로고
    • The effect of chronic aluminium (III) administration on the nervous system of aged rats: clues to understand its suggested role in Alzheimer's disease
    • P Fattoretti, C Bertoni-Freddari, M Balietti, E Mocchegiani, J Scancar, P Zambenedetti and P Zatta (2003) The effect of chronic aluminium (III) administration on the nervous system of aged rats: clues to understand its suggested role in Alzheimer's disease. J Alzheimers Dis. 5 437-444.
    • (2003) J Alzheimers Dis. , vol.5 , pp. 437-444
    • Fattoretti, P.1    Bertoni-Freddari, C.2    Balietti, M.3    Mocchegiani, E.4    Scancar, J.5    Zambenedetti, P.6    Zatta, P.7
  • 128
    • 27744545492 scopus 로고    scopus 로고
    • Alterations in zinc transporter protein-1 (ZnT-1) in the brain of subjects with mild cognitive impairment, early, and late-stage Alzheimer's disease
    • MA Lovell, JL Smith, S Xiong and WR Markesbery (2005) Alterations in zinc transporter protein-1 (ZnT-1) in the brain of subjects with mild cognitive impairment, early, and late-stage Alzheimer's disease. Neurotox Res. 7 265-271.
    • (2005) Neurotox Res. , vol.7 , pp. 265-271
    • Lovell, M.A.1    Smith, J.L.2    Xiong, S.3    Markesbery, W.R.4
  • 129
    • 28544431728 scopus 로고    scopus 로고
    • 4-Hydroxynonenal disrupts zinc export in primary rat cortical cells
    • in press
    • JL Smith, S Xiong and MA Lovell (2006) 4-Hydroxynonenal disrupts zinc export in primary rat cortical cells. Neurotoxicology in press
    • (2006) Neurotoxicology
    • Smith, J.L.1    Xiong, S.2    Lovell, M.A.3
  • 131
    • 0037087150 scopus 로고    scopus 로고
    • Aggregation of alpha-synuclein induced by the Cu,Zn-superoxide dismutase and hydrogen peroxide system
    • KS Kim, SY Choi, HY Kwon, MH Won, TC Kang and JH Kang (2002) Aggregation of alpha-synuclein induced by the Cu,Zn-superoxide dismutase and hydrogen peroxide system. Free Radic Biol Med. 32 544-550.
    • (2002) Free Radic Biol Med. , vol.32 , pp. 544-550
    • Kim, K.S.1    Choi, S.Y.2    Kwon, H.Y.3    Won, M.H.4    Kang, T.C.5    Kang, J.H.6
  • 133
    • 10644276189 scopus 로고    scopus 로고
    • Mitochondria as a primary target for vascular hypoperfusion and oxidative stress in Alzheimer's disease
    • G Aliev, MA Smith, T.J.C. de la Torre JC and G Perry (2004) Mitochondria as a primary target for vascular hypoperfusion and oxidative stress in Alzheimer's disease. Mitochondrion 4 649-663.
    • (2004) Mitochondrion , vol.4 , pp. 649-663
    • Aliev, G.1    Smith, M.A.2    la de, T.J.C.3    Perry, G.4
  • 134
    • 22144485957 scopus 로고    scopus 로고
    • ROS effects on neurodegeneration in Alzheimer's disease and related disorders: on environmental stresses of ionizing radiation
    • KG Manton, S Volovik and A Kulminski (2004) ROS effects on neurodegeneration in Alzheimer's disease and related disorders: on environmental stresses of ionizing radiation. Curr Alzheimer Res. 1 277-293.
    • (2004) Curr Alzheimer Res. , vol.1 , pp. 277-293
    • Manton, K.G.1    Volovik, S.2    Kulminski, A.3
  • 137
    • 0034641918 scopus 로고    scopus 로고
    • The biochemistry of apoptosis
    • MO Hengartner (2000) The biochemistry of apoptosis. Nature 407 770-776.
    • (2000) Nature , vol.407 , pp. 770-776
    • Hengartner, M.O.1
  • 138
    • 0032437256 scopus 로고    scopus 로고
    • Signal transduction pathways that regulate cell survival and cell death
    • T Dragovich, CM Rudin and CB Thompson (1998) Signal transduction pathways that regulate cell survival and cell death. Oncogene 17 3207-3213.
    • (1998) Oncogene , vol.17 , pp. 3207-3213
    • Dragovich, T.1    Rudin, C.M.2    Thompson, C.B.3
  • 139
    • 27844495164 scopus 로고    scopus 로고
    • Molecular basis of programmed cell death involved in neurodegeneration
    • S Krantic, N Mechawar, S Reix and R Quirion (2005) Molecular basis of programmed cell death involved in neurodegeneration. Trends Neurosci. 28(12), 670-676.
    • (2005) Trends Neurosci. , vol.28 , Issue.12 , pp. 670-676
    • Krantic, S.1    Mechawar, N.2    Reix, S.3    Quirion, R.4
  • 140
    • 0034767382 scopus 로고    scopus 로고
    • Apoptosis and aging: role of the mitochondria
    • M Pollack and C Leeuwenburgh (2001) Apoptosis and aging: role of the mitochondria. J Gerontol A Biol Sci Med Sci. 56(11), B475-B482.
    • (2001) J Gerontol A Biol Sci Med Sci. , vol.56 , Issue.11 , pp. B475-B482
    • Pollack, M.1    Leeuwenburgh, C.2
  • 141
    • 0033929763 scopus 로고    scopus 로고
    • Apoptosis in the aging process
    • Y Higami and I Shimokawa (2000) Apoptosis in the aging process. Cell Tissue Res. 301 125-132.
    • (2000) Cell Tissue Res. , vol.301 , pp. 125-132
    • Higami, Y.1    Shimokawa, I.2
  • 142
    • 0347479366 scopus 로고    scopus 로고
    • Accumulation of caspase cleaved amyloid precursor protein represents an early neurodegenerative event in aging and in Alzheimer's disease
    • M Zhao, J Su, E Head and CW Cotman (2003) Accumulation of caspase cleaved amyloid precursor protein represents an early neurodegenerative event in aging and in Alzheimer's disease. Neurobiol Dis. 14(3), 391-403.
    • (2003) Neurobiol Dis. , vol.14 , Issue.3 , pp. 391-403
    • Zhao, M.1    Su, J.2    Head, E.3    Cotman, C.W.4
  • 144
    • 0030831489 scopus 로고    scopus 로고
    • Correlates of p53-and Fas (CD95) -mediated apoptosis in Alzheimer's disease
    • M.S.M. De la Monte SM, YK Sohn and JR Wands (1997) Correlates of p53-and Fas (CD95) -mediated apoptosis in Alzheimer's disease. J Neurol Sci. 152(1), 73-83.
    • (1997) J Neurol Sci. , vol.152 , Issue.1 , pp. 73-83
    • la De, M.S.M.1    Sohn, Y.K.2    Wands, J.R.3
  • 146
    • 0031013141 scopus 로고    scopus 로고
    • Apoptotic-like changes in Lewy-body-associated disorders and normal aging in substantia nigral neurons
    • MM Tompkins, EJ Basgall, E Zamrini and WD Hill (1997) Apoptotic-like changes in Lewy-body-associated disorders and normal aging in substantia nigral neurons. Am J Pathol. 150(1), 119-131.
    • (1997) Am J Pathol. , vol.150 , Issue.1 , pp. 119-131
    • Tompkins, M.M.1    Basgall, E.J.2    Zamrini, E.3    Hill, W.D.4
  • 147
    • 0031719120 scopus 로고    scopus 로고
    • Autosomal dominant Parkinson's disease and alpha-synuclein
    • MH Polymeropoulos (1998) Autosomal dominant Parkinson's disease and alpha-synuclein. Ann Neurol. 44 S63-S64.
    • (1998) Ann Neurol. , vol.44 , pp. S63-S64
    • Polymeropoulos, M.H.1
  • 148
    • 5444249974 scopus 로고    scopus 로고
    • Overexpression of alpha-synuclein in rat substantia nigra results in loss of dopaminergic neurons, phosphorylation of alpha-synuclein and activation of caspas
    • M Yamada, T Iwatsubo, Y Mizuno and H Mochizuki (2004) Overexpression of alpha-synuclein in rat substantia nigra results in loss of dopaminergic neurons, phosphorylation of alpha-synuclein and activation of caspas. J Neurochem. 91 451-461.
    • (2004) J Neurochem. , vol.91 , pp. 451-461
    • Yamada, M.1    Iwatsubo, T.2    Mizuno, Y.3    Mochizuki, H.4
  • 149
    • 0942287085 scopus 로고    scopus 로고
    • Programmed cell death in amyotrophic lateral sclerosis: a mechanism of pathogenic and therapeutic importance
    • S Przedborski (2004) Programmed cell death in amyotrophic lateral sclerosis: a mechanism of pathogenic and therapeutic importance. Neurologist 10(1), 1-7.
    • (2004) Neurologist , vol.10 , Issue.1 , pp. 1-7
    • Przedborski, S.1
  • 150
    • 0028283985 scopus 로고
    • Glutamine repeats as polar zippers: their possible role in inherited neurodegenerative diseases
    • MF Perutz, T Johnson, M Suzuki and JT Finch (1994) Glutamine repeats as polar zippers: their possible role in inherited neurodegenerative diseases. Proc Natl Acad Sci USA 91(12), 5355-5358.
    • (1994) Proc Natl Acad Sci USA , vol.91 , Issue.12 , pp. 5355-5358
    • Perutz, M.F.1    Johnson, T.2    Suzuki, M.3    Finch, J.T.4
  • 151
    • 0034703874 scopus 로고    scopus 로고
    • Intranuclear huntingtin increases the expression of caspase-1 and induces apoptosis
    • SH Li, S Lam, AL Cheng and XJ Li (2000) Intranuclear huntingtin increases the expression of caspase-1 and induces apoptosis. Hum Mol Genet. 9(19), 2859-2867.
    • (2000) Hum Mol Genet. , vol.9 , Issue.19 , pp. 2859-2867
    • Li, S.H.1    Lam, S.2    Cheng, A.L.3    Li, X.J.4
  • 152
  • 153
    • 0141705360 scopus 로고    scopus 로고
    • Mitochondrial dysfunction and reactive oxygen species in excitotoxicity and apoptosis: implications for the pathogenesis of neurodegenerative diseases
    • AC Rego and CR Oliveira (2003) Mitochondrial dysfunction and reactive oxygen species in excitotoxicity and apoptosis: implications for the pathogenesis of neurodegenerative diseases. Neurochem Res. 28(10), 1563-1574.
    • (2003) Neurochem Res. , vol.28 , Issue.10 , pp. 1563-1574
    • Rego, A.C.1    Oliveira, C.R.2
  • 154
    • 17144434775 scopus 로고    scopus 로고
    • Poly (ADP-ribose) polymerase inhi-bition protect neurons and the white matter and regulates the translocation of apoptosis-inducing factor in stroke
    • K Komjati, JG Mabley, L Virag, GJ Southan, AL Salzman and C Szabo (2004) Poly (ADP-ribose) polymerase inhi-bition protect neurons and the white matter and regulates the translocation of apoptosis-inducing factor in stroke. Int J Mol Med. 13 373-382.
    • (2004) Int J Mol Med. , vol.13 , pp. 373-382
    • Komjati, K.1    Mabley, J.G.2    Virag, L.3    Southan, G.J.4    Salzman, A.L.5    Szabo, C.6
  • 156
    • 0031661968 scopus 로고    scopus 로고
    • The cell division cycle and the pathophysiology of Alzheimer's disease
    • Z Nagy, MM Esiri and AD Smith (1998) The cell division cycle and the pathophysiology of Alzheimer's disease. Neuroscience 87(4), 731-739.
    • (1998) Neuroscience , vol.87 , Issue.4 , pp. 731-739
    • Nagy, Z.1    Esiri, M.M.2    Smith, A.D.3
  • 157
    • 0344241479 scopus 로고    scopus 로고
    • Neuronal cell death is preceded by cell cycle events at all stages of Alzheimer's disease
    • Y Yang, EJ Mufson and K Herrup (2003) Neuronal cell death is preceded by cell cycle events at all stages of Alzheimer's disease. J Neurosci. 23(7), 2557-2563.
    • (2003) J Neurosci. , vol.23 , Issue.7 , pp. 2557-2563
    • Yang, Y.1    Mufson, E.J.2    Herrup, K.3
  • 159
    • 9644270708 scopus 로고    scopus 로고
    • Dementia-free centenarians
    • T Perls (2004) Dementia-free centenarians. Exp Gerontol. 39 1587-1593.
    • (2004) Exp Gerontol. , vol.39 , pp. 1587-1593
    • Perls, T.1
  • 160
    • 0345540639 scopus 로고    scopus 로고
    • Centenarians: the older you get, the healthier you have been
    • R Hitt, Y Young-Xu, M Silver and T Perls (1999) Centenarians: the older you get, the healthier you have been. Lancet 354 652.
    • (1999) Lancet , vol.354 , pp. 652
    • Hitt, R.1    Young-Xu, Y.2    Silver, M.3    Perls, T.4
  • 161
    • 1642416504 scopus 로고
    • Evolution of human longevity and the genetic complexity governing aging rate
    • RG Cutler (1975) Evolution of human longevity and the genetic complexity governing aging rate. Proc Natl Acad Sci USA 72 4664-4668.
    • (1975) Proc Natl Acad Sci USA , vol.72 , pp. 4664-4668
    • Cutler, R.G.1
  • 162
    • 0036900066 scopus 로고    scopus 로고
    • Genetic and environmental factors in cancer and neurodegenerative diseases
    • L Migliore and F Coppedè (2002) Genetic and environmental factors in cancer and neurodegenerative diseases. Mutat Res. 512 135-153.
    • (2002) Mutat Res. , vol.512 , pp. 135-153
    • Migliore, L.1    Coppedè, F.2
  • 163
    • 2542427690 scopus 로고    scopus 로고
    • Oligomers on the brain: the emerging role of soluble protein aggregates in neurodegeneration
    • DM Walsh and DJ Selkoe (2004) Oligomers on the brain: the emerging role of soluble protein aggregates in neurodegeneration. Protein Pept Lett. 11 213-228.
    • (2004) Protein Pept Lett. , vol.11 , pp. 213-228
    • Walsh, D.M.1    Selkoe, D.J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.