Is oxidative damage the fundamental pathogenic mechanism of Alzheimer's and other neurodegenerative diseases?

Free Radical Biology and Medicine

Volumn 33, Issue 11, 2002, Pages 1475-1479

  Perry, George ^a   Nunomura, Akihiko ^a,b   Hirai, Keisuke ^a,c   Zhu, Xiongwei ^a   Prez, Mar ^d   Avila, Jess ^d   Castellani, Rudolph J ^a   Atwood, Craig S ^a   Aliev, Gjumrakch ^a   Sayre, Lawrence M ^a   Takeda, Atsushi ^a,e   Smith, Mark A ^a  

^a CASE WESTERN RESERVE UNIVERSITY   (United States)

^b ASAHIKAWA MEDICAL COLLEGE   (Japan)

^c TAKEDA PHARMACEUTICAL COMPANY LIMITED   (Japan)

^d UNIVERSIDAD AUTÓNOMA DE MADRID   (Spain)

^e TOHOKU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Alzheimer's disease; Amyloid ; Antioxidants; Free radicals; Homeostasis; Neurofibrillary tangles; Oxidative stress; Redox balance; Senile plaque;

Indexed keywords

AMYLOID BETA PROTEIN; REACTIVE OXYGEN METABOLITE; FREE RADICAL;

ALZHEIMER DISEASE; BRAIN REGION; CLINICAL FEATURE; DEGENERATIVE DISEASE; HUMAN; NEUROFIBRILLARY TANGLE; NEUROPATHOLOGY; OXIDATIVE STRESS; PATHOGENESIS; PRIORITY JOURNAL; REVIEW; ANIMAL; METABOLISM; OXIDATION REDUCTION REACTION; PATHOLOGY;

ALZHEIMER DISEASE; ANIMALS; FREE RADICALS; HUMANS; NEURODEGENERATIVE DISEASES; OXIDATION-REDUCTION; OXIDATIVE STRESS; REACTIVE OXYGEN SPECIES;

EID: 18744374615     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0891-5849(02)01113-9     Document Type: Article

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