Association between the interleukin-1α gene and Alzheimer's disease: A meta-analysis

Neurobiology of Aging

Volumn 25, Issue 10, 2004, Pages 1293-1298

  Rainero, I ^a   Bo, M ^a   Ferrero, M ^a   Valfre W ^a   Vaula, G ^b   Pinessi, L ^a  

^a UNIVERSITY OF TURIN   (Italy)

^b Ospedale di Ivrea   (Italy)

Author keywords

Alzheimer's disease; Interleukin 1 genes; Meta analysis; Polymorphism

Indexed keywords

INTERLEUKIN 1ALPHA; INTERLEUKIN 1;

ALZHEIMER DISEASE; ARTICLE; GENE FREQUENCY; GENETIC ANALYSIS; GENETIC HETEROGENEITY; GENETIC POLYMORPHISM; GENETIC RISK; GENOTYPE; HUMAN; PRIORITY JOURNAL; RISK FACTOR; AGED; CLINICAL TRIAL; COMORBIDITY; FEMALE; GENETIC PREDISPOSITION; GENETICS; MALE; META ANALYSIS; METHODOLOGY; MIDDLE AGED; MUTATION; PHENOTYPE; RISK ASSESSMENT;

AGED; ALZHEIMER DISEASE; COMORBIDITY; FEMALE; GENETIC PREDISPOSITION TO DISEASE; HUMANS; INTERLEUKIN-1; MALE; MIDDLE AGED; MUTATION; PHENOTYPE; RISK ASSESSMENT; RISK FACTORS;

EID: 4644234931     PISSN: 01974580     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neurobiolaging.2004.02.011     Document Type: Article

References (30)

1. Arend W.P. The balance between IL-1 and IL-1Ra in disease. Cytokine Growth Factor Rev. 13:2002;323-340
2. Combarros O., Sanche-Guerra M., Infante J., Llorca J., Berciano J. Gene dose-dependent association of interleukin-1A (-889) allele polymorphism with Alzheimer's disease. J. Neurol. 249:2002;1242-1245
3. Das S., Potter H. Expression of the Alzheimer amyloid-promoting factor antichymotrypsin is induced in human astrocytes by IL-1. Neuron. 14:1995;447-456
4. Dominici R., Cattaneo M., Malferrari G., Archi D., Mariani C., Grimaldi L.M., et al. Cloning and functional analysis of the allelic polymorphism in the transcription regulatory region of interleukin-1 alpha. Immunogenetics. 54:2002;82-86
5. Du Y., Dodel R.C., Eastwood B.J., Bales K.R., Gao F., Muller U., et al. Griffin WS.T., Association of interleukin 1α polymorphism with Alzheimer's disease. Neurology. 55:2000;480-483
6. Eikelenboom P., Veerhuis R. The role of complement and activated microglia in the pathogenesis of Alzheimer's disease. Neurobiol Aging. 17:1996;673-680
7. Goldgaber D., Harris H.W., Hla T., Maciag T., Donnelly R.J., Jacobsen J.S., et al. Interleukin 1 regulates synthesis of amyloid beta-protein precursor mRNA in human endothelial cells. Proc. Natl. Acad. Sci. USA. 86:1989;7606-7610
8. Green E.K., Harris J.M., Lemmon H., Lambert J.C., Chartier-Harlin M.C., St. Clair D., et al. Are interleukin-1 gene polymorphisms risk factors or disease modifiers in AD? Neurology. 58:2002;1566-1568
9. Griffin W.S., Nicoll J.A., Grimaldi L.M., Sheng J.G., Mrak R.E. The pervasiveness of interleukin-1 in Alzheimer pathogenesis: a role for specific polymorphisms in disease risk. Exp. Gerontol. 35:2000;481-487
10. Griffin W.S., Sheng J.G., Roberts G.W., Mrak R.E. Interleukin-1 expression in different plaque types in Alzheimer's disease: significance in plaque evolution. J. Neuropathol. Exp. Neurol. 54:1995;276-281
11. Grimaldi L., Casadei C., Ferri C., Veglia F., Licastro F., Annoni G., et al. Association of early-onset Alzheimer's disease with an interleukin-1α gene polymorphism. Ann. Neurol. 47:2000;361-365
12. Hedley R., Hallmayer J., Groth D.M., Brooks W.S., Gandy S.E., et al. Association of interleukin-1 polymorphisms with Alzheimer's Disease in Australia. Ann. Neurol. 51:2002;795-797
13. Ki C.S., Lyul D., Kwan Kim D., Jin Kim H., Kim J.W. Lack of association of the interleukin-1α gene polymorphism with Alzheimer's Disease in a Korean Population. Ann. Neurol. 49:2001;817-818
14. Kuo Y.M., Liao P.C., Lin C., Wu C.W., Huang H.M., Lin C.C., et al. Lack of association between interleukin-1α polymorphism and Alzheimer disease or vascular dementia. Alzheimer Dis. Associated Disorders. 17:2003;94-97
15. Li Y., Liu L., Kang J., Sheng J.G., Barger S.W., Mrak R.E., et al. Neuronal-glial interactions mediated by interleukin-1 enhance neuronal acetylcholinesterase activity and mRNA expression. J. Neurosci. 20:2000;149-155
16. McKhann G., Drachman D., Folstein M., Katzman R., Price D., Stadlan E.M. Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease. Neurology. 34:1984;939-944
17. Minster R.L., DeKosky S.T., Ganguli M., Belle S., Kamboh M.I. Genetic association studies of interleukin-1 (IL-1A and IL-1B) and interleukin-1 receptor antagonist genes and risk of Alzheimer's disease. Ann. Neurol. 48:2000;817-819
18. Mrak R.E., Griffin W.S.T. Interleukin-1, neuroinflammation, and Alzheimer's disease. Neurobiol. Aging. 22:2001;903-908
19. Nicoll J.A.R., Mrak R.E., Graham D.I., Stewart J., Wilcock G., Mac Gowan S., et al. Association of Interleukin-1 gene polymorphisms with Alzheimer's disease. Ann. Neurol. 47:2000;365-368
20. Patel H.C., Boutin H., Allan S.M. Interleukin-1 in the brain: mechanisms of action in acute neurodegeneration. Ann. NY Acad. Sci. 992:2003;39-47
21. Pirskanen M., Hiltunen M., Mannermaa A., Livonen S., Helisalmi S., Lehtovirta M., et al. Interleukin 1 alpha gene polymorphism as a susceptibility factor in Alzheimer's Disease and its influence on the extent of histopathological hallmark lesions of Alzheimer's Disease. Dement. Geriat. Cogn. Disord. 14:2002;123-127
22. Rebeck G.W. Confirmation of the genetic association of interleukin-1 A with early onset sporadic Alzheimer's disease. Neurosci. Lett. 293:2000;75-77
23. Rogers J., Webster S., Lue L.F., Brachova L., Civin W.H., Emmerling M., et al. Inflammation and Alzheimer's disease pathogenesis. Neurobiol. Aging. 17:1996;681-686
24. Rothwell N.J. Functions and mechanisms of interleukin 1 in the brain. Trends Pharmacol. Sci. 12:1991;430-436
25. Rothwell N.J., Luheshi G.N. Interleukin 1 in the brain: biology, pathology and therapeutic target. Trends Neurosci. 23:2000;618-625
26. Sheng J.G., Griffin W.S., Royston M.C., Mrak R.E. Distribution of interleukin-1-immunoreactive microglia in cerebral cortical layers: implications for neuritic plaque formation in Alzheimer's disease. Neuropathol. Appl. Neurobiol. 24:1998;278-283
27. Shirodaria S., Smith J., McKay I.J., Kennet C.N., Hughes F.J. Polymorphisms in the IL-1A gene are correlated with levels of interlukin-1alpha protein in gingival cervicular fluid of teeth with severe periodontal disease. J. Dent. Res. 79:2000;1864-1869
28. Streit W.J., Conde J.R., Harrison J.K. Chemokines and Alzheimer's disease. Neurobiol. Aging. 22:2001;909-913
29. Taylor S.L., Renshaw B.R., Garka K.E., Smith D.E., Sims J.E. Genomic organization of the interleukin-1 locus. Genomics. 79:2002;726-733
30. Tsai S.J., Liu H.C., Liu T.Y., Wang K.Y., Hong C.J. Lack of association between the interleukin-1 alpha gene C (-889) T polymorphism and Alzheimer's disease in a Chinese population. Neurosci. Lett. 343:2003;93-96