-
1
-
-
24144494563
-
The let-7 MicroRNA family members mir-48, mir-84, and mir-241 function together to regulate developmental timing in Caenorhabditis elegans
-
Abbott A.L., Alvarez-Saavedra E., Miska E.A., Lau N.C., Bartel D.P., Horvitz H.R., et al. The let-7 MicroRNA family members mir-48, mir-84, and mir-241 function together to regulate developmental timing in Caenorhabditis elegans. Developmental Cell 2005, 9:403-414.
-
(2005)
Developmental Cell
, vol.9
, pp. 403-414
-
-
Abbott, A.L.1
Alvarez-Saavedra, E.2
Miska, E.A.3
Lau, N.C.4
Bartel, D.P.5
Horvitz, H.R.6
-
2
-
-
0031874860
-
Identification of heterochronic mutants in Caenorhabditis elegans: Temporal misexpression of a collagen::green fluorescent protein fusion gene
-
Abrahante J.E., Miller E.A., Rougvie A.E. Identification of heterochronic mutants in Caenorhabditis elegans: Temporal misexpression of a collagen::green fluorescent protein fusion gene. Genetics 1998, 149:1335-1351.
-
(1998)
Genetics
, vol.149
, pp. 1335-1351
-
-
Abrahante, J.E.1
Miller, E.A.2
Rougvie, A.E.3
-
3
-
-
34447635075
-
-
Amador-Noguez D., Dean A., Huang W., Setchell K., Moore D., Darlington G. Alterations in xenobiotic metabolism in the long-lived Little mice. Aging cell 2007, 6:453-470.
-
(2007)
Alterations in xenobiotic metabolism in the long-lived Little mice. Aging cell
, vol.6
, pp. 453-470
-
-
Amador-Noguez, D.1
Dean, A.2
Huang, W.3
Setchell, K.4
Moore, D.5
Darlington, G.6
-
4
-
-
0021771445
-
Heterochronic mutants of the nematode C. elegans
-
Ambros V., Horvitz H.R. Heterochronic mutants of the nematode C. elegans. Science 1984, 226:409-416.
-
(1984)
Science
, vol.226
, pp. 409-416
-
-
Ambros, V.1
Horvitz, H.R.2
-
5
-
-
72449170138
-
Starvation protects germline stem cells and extends reproductive longevity in C. elegans
-
Angelo G., Van Gilst M.R. Starvation protects germline stem cells and extends reproductive longevity in C. elegans. Science 2009, 326:954-958.
-
(2009)
Science
, vol.326
, pp. 954-958
-
-
Angelo, G.1
Van Gilst, M.R.2
-
6
-
-
0031947155
-
Daf-12 regulates developmental age and the dauer alternative in Caenorhabditis elegans
-
Antebi A., Culotti J.G., Hedgecock E.M. daf-12 regulates developmental age and the dauer alternative in Caenorhabditis elegans. Development 1998, 125:1191-1205.
-
(1998)
Development
, vol.125
, pp. 1191-1205
-
-
Antebi, A.1
Culotti, J.G.2
Hedgecock, E.M.3
-
7
-
-
0034659485
-
Daf-12 encodes a nuclear receptor that regulates the dauer diapause and developmental age in C. elegans
-
Antebi A., Yeh W.H., Tait D., Hedgecock E.M., Riddle D.L. daf-12 encodes a nuclear receptor that regulates the dauer diapause and developmental age in C. elegans. Genes & Development 2000, 14:1512-1527.
-
(2000)
Genes & Development
, vol.14
, pp. 1512-1527
-
-
Antebi, A.1
Yeh, W.H.2
Tait, D.3
Hedgecock, E.M.4
Riddle, D.L.5
-
8
-
-
0037127026
-
Regulation of life-span by germ-line stem cells in Caenorhabditis elegans
-
Arantes-Oliveira N., Apfeld J., Dillin A., Kenyon C. Regulation of life-span by germ-line stem cells in Caenorhabditis elegans. Science 2002, 295:502-505.
-
(2002)
Science
, vol.295
, pp. 502-505
-
-
Arantes-Oliveira, N.1
Apfeld, J.2
Dillin, A.3
Kenyon, C.4
-
9
-
-
0033825448
-
The conserved nuclear receptor Ftz-F1 is required for embryogenesis, moulting and reproduction in Caenorhabditis elegans
-
Asahina M., Ishihara T., Jindra M., Kohara Y., Katsura I., Hirose S. The conserved nuclear receptor Ftz-F1 is required for embryogenesis, moulting and reproduction in Caenorhabditis elegans. Genes to Cells 2000, 5(9):711-723.
-
(2000)
Genes to Cells
, vol.5
, Issue.9
, pp. 711-723
-
-
Asahina, M.1
Ishihara, T.2
Jindra, M.3
Kohara, Y.4
Katsura, I.5
Hirose, S.6
-
10
-
-
84868238432
-
Heat shock factor-1 intertwines insulin/IGF-1, TGF-beta and cGMP signaling to control development and aging
-
Barna J., Princz A., Kosztelnik M., Hargitai B., Takacs-Vellai K., Vellai T. Heat shock factor-1 intertwines insulin/IGF-1, TGF-beta and cGMP signaling to control development and aging. BMC Developmental Biology 2012, 12:32.
-
(2012)
BMC Developmental Biology
, vol.12
, pp. 32
-
-
Barna, J.1
Princz, A.2
Kosztelnik, M.3
Hargitai, B.4
Takacs-Vellai, K.5
Vellai, T.6
-
11
-
-
77954956884
-
Co-option of the hormone-signalling module dafachronic acid-DAF-12 in nematode evolution
-
Bento G., Ogawa A., Sommer R.J. Co-option of the hormone-signalling module dafachronic acid-DAF-12 in nematode evolution. Nature 2010, 466:494-497.
-
(2010)
Nature
, vol.466
, pp. 494-497
-
-
Bento, G.1
Ogawa, A.2
Sommer, R.J.3
-
12
-
-
33644772542
-
Germ-cell loss extends C. elegans life span through regulation of DAF-16 by kri-1 and lipophilic-hormone signaling
-
Berman J.R., Kenyon C. Germ-cell loss extends C. elegans life span through regulation of DAF-16 by kri-1 and lipophilic-hormone signaling. Cell 2006, 124:1055-1068.
-
(2006)
Cell
, vol.124
, pp. 1055-1068
-
-
Berman, J.R.1
Kenyon, C.2
-
13
-
-
64249129511
-
Nuclear hormone receptor regulation of microRNAs controls developmental progression
-
Bethke A., Fielenbach N., Wang Z., Mangelsdorf D.J., Antebi A. Nuclear hormone receptor regulation of microRNAs controls developmental progression. Science 2009, 324:95-98.
-
(2009)
Science
, vol.324
, pp. 95-98
-
-
Bethke, A.1
Fielenbach, N.2
Wang, Z.3
Mangelsdorf, D.J.4
Antebi, A.5
-
14
-
-
69049096130
-
Estradiol-regulated microRNAs control estradiol response in breast cancer cells
-
Bhat-Nakshatri P., Wang G., Collins N.R., Thomson M.J., Geistlinger T.R., Carroll J.S., et al. Estradiol-regulated microRNAs control estradiol response in breast cancer cells. Nucleic Acids Research 2009, 37:4850-4861.
-
(2009)
Nucleic Acids Research
, vol.37
, pp. 4850-4861
-
-
Bhat-Nakshatri, P.1
Wang, G.2
Collins, N.R.3
Thomson, M.J.4
Geistlinger, T.R.5
Carroll, J.S.6
-
15
-
-
29344467120
-
A developmental timing microRNA and its target regulate life span in C. elegans
-
Boehm M., Slack F. A developmental timing microRNA and its target regulate life span in C. elegans. Science 2005, 310:1954-1957.
-
(2005)
Science
, vol.310
, pp. 1954-1957
-
-
Boehm, M.1
Slack, F.2
-
16
-
-
34250760886
-
Small-molecule pheromones that control dauer development in Caenorhabditis elegans
-
Butcher R.A., Fujita M., Schroeder F.C., Clardy J. Small-molecule pheromones that control dauer development in Caenorhabditis elegans. Nature Chemical Biology 2007, 3:420-422.
-
(2007)
Nature Chemical Biology
, vol.3
, pp. 420-422
-
-
Butcher, R.A.1
Fujita, M.2
Schroeder, F.C.3
Clardy, J.4
-
17
-
-
0016766716
-
The dauer-larva: A post-embryonic developmental variant of the nematode C. elegans
-
Cassada R., Russell R. The dauer-larva: A post-embryonic developmental variant of the nematode C. elegans. Developmental Biology 1975, 46:326-342.
-
(1975)
Developmental Biology
, vol.46
, pp. 326-342
-
-
Cassada, R.1
Russell, R.2
-
18
-
-
84863329878
-
Trim71 cooperates with microRNAs to repress Cdkn1a expression and promote embryonic stem cell proliferation
-
Chang H.M., Martinez N.J., Thornton J.E., Hagan J.P., Nguyen K.D., Gregory R.I. Trim71 cooperates with microRNAs to repress Cdkn1a expression and promote embryonic stem cell proliferation. Nature Communications 2012, 3:923.
-
(2012)
Nature Communications
, vol.3
, pp. 923
-
-
Chang, H.M.1
Martinez, N.J.2
Thornton, J.E.3
Hagan, J.P.4
Nguyen, K.D.5
Gregory, R.I.6
-
19
-
-
84859830814
-
Hormonal activation of let-7-C microRNAs via EcR is required for adult Drosophila melanogaster morphology and function
-
Chawla G., Sokol N.S. Hormonal activation of let-7-C microRNAs via EcR is required for adult Drosophila melanogaster morphology and function. Development 2012, 139:1788-1797.
-
(2012)
Development
, vol.139
, pp. 1788-1797
-
-
Chawla, G.1
Sokol, N.S.2
-
20
-
-
0842301558
-
DAF-5 is a Ski oncoprotein homolog that functions in a neuronal TGF beta pathway to regulate C. elegans dauer development
-
da Graca L.S., Zimmerman K.K., Mitchell M.C., Kozhan-Gorodetska M., Sekiewicz K., Morales Y., et al. DAF-5 is a Ski oncoprotein homolog that functions in a neuronal TGF beta pathway to regulate C. elegans dauer development. Development 2004, 131:435-446.
-
(2004)
Development
, vol.131
, pp. 435-446
-
-
da Graca, L.S.1
Zimmerman, K.K.2
Mitchell, M.C.3
Kozhan-Gorodetska, M.4
Sekiewicz, K.5
Morales, Y.6
-
21
-
-
23744492247
-
The developmental timing regulator AIN-1 interacts with miRISCs and may target the argonaute protein ALG-1 to cytoplasmic P bodies in C. elegans
-
Ding L., Spencer A., Morita K., Han M. The developmental timing regulator AIN-1 interacts with miRISCs and may target the argonaute protein ALG-1 to cytoplasmic P bodies in C. elegans. Molecular Cell 2005, 19:437-447.
-
(2005)
Molecular Cell
, vol.19
, pp. 437-447
-
-
Ding, L.1
Spencer, A.2
Morita, K.3
Han, M.4
-
22
-
-
28444441562
-
Post-embryonic expression of C. elegans microRNAs belonging to the lin-4 and let-7 families in the hypodermis and the reproductive system
-
Esquela-Kerscher A., Johnson S.M., Bai L., Saito K., Partridge J., Reinert K.L., et al. Post-embryonic expression of C. elegans microRNAs belonging to the lin-4 and let-7 families in the hypodermis and the reproductive system. Developmental Dynamics 2005, 234:868-877.
-
(2005)
Developmental Dynamics
, vol.234
, pp. 868-877
-
-
Esquela-Kerscher, A.1
Johnson, S.M.2
Bai, L.3
Saito, K.4
Partridge, J.5
Reinert, K.L.6
-
23
-
-
0027373733
-
The daf-4 gene encodes a bone morphogenetic protein receptor controlling C. elegans dauer larva development
-
Estevez M., Attisano L., Wrana J.L., Albert P.S., Massague J., Riddle D.L. The daf-4 gene encodes a bone morphogenetic protein receptor controlling C. elegans dauer larva development. Nature 1993, 365:644-649.
-
(1993)
Nature
, vol.365
, pp. 644-649
-
-
Estevez, M.1
Attisano, L.2
Wrana, J.L.3
Albert, P.S.4
Massague, J.5
Riddle, D.L.6
-
24
-
-
0029813901
-
Reversal of cell fate determination in Caenorhabditis elegans vulval development
-
Euling S., Ambros V. Reversal of cell fate determination in Caenorhabditis elegans vulval development. Development 1996, 122:2507-2515.
-
(1996)
Development
, vol.122
, pp. 2507-2515
-
-
Euling, S.1
Ambros, V.2
-
25
-
-
50049116926
-
C. elegans dauer formation and the molecular basis of plasticity
-
Fielenbach N., Antebi A. C. elegans dauer formation and the molecular basis of plasticity. Genes & Development 2008, 22:2149-2165.
-
(2008)
Genes & Development
, vol.22
, pp. 2149-2165
-
-
Fielenbach, N.1
Antebi, A.2
-
26
-
-
33847221398
-
DRE-1: An evolutionarily conserved F box protein that regulates C. elegans developmental age
-
Fielenbach N., Guardavaccaro D., Neubert K., Chan T., Li D., Feng Q., et al. DRE-1: An evolutionarily conserved F box protein that regulates C. elegans developmental age. Developmental Cell 2007, 12:443-455.
-
(2007)
Developmental Cell
, vol.12
, pp. 443-455
-
-
Fielenbach, N.1
Guardavaccaro, D.2
Neubert, K.3
Chan, T.4
Li, D.5
Feng, Q.6
-
27
-
-
0025281396
-
Daf-1, a C. elegans gene controlling dauer larva development, encodes a novel receptor protein kinase
-
Georgi L.L., Albert P.S., Riddle D.L. daf-1, a C. elegans gene controlling dauer larva development, encodes a novel receptor protein kinase. Cell 1990, 61:635-645.
-
(1990)
Cell
, vol.61
, pp. 635-645
-
-
Georgi, L.L.1
Albert, P.S.2
Riddle, D.L.3
-
28
-
-
2342420089
-
Hormonal signals produced by DAF-9/cytochrome P450 regulate C. elegans dauer diapause in response to environmental cues
-
Gerisch B., Antebi A. Hormonal signals produced by DAF-9/cytochrome P450 regulate C. elegans dauer diapause in response to environmental cues. Development 2004, 131:1765-1776.
-
(2004)
Development
, vol.131
, pp. 1765-1776
-
-
Gerisch, B.1
Antebi, A.2
-
29
-
-
34247563364
-
A bile acid-like steroid modulates Caenorhabditis elegans lifespan through nuclear receptor signaling
-
Gerisch B., Rottiers V., Li D., Motola D.L., Cummins C.L., Lehrach H., et al. A bile acid-like steroid modulates Caenorhabditis elegans lifespan through nuclear receptor signaling. Proceedings of the National Academy of Sciences of the United States of America 2007, 104:5014-5019.
-
(2007)
Proceedings of the National Academy of Sciences of the United States of America
, vol.104
, pp. 5014-5019
-
-
Gerisch, B.1
Rottiers, V.2
Li, D.3
Motola, D.L.4
Cummins, C.L.5
Lehrach, H.6
-
30
-
-
0035656274
-
A hormonal signaling pathway influencing C. elegans metabolism, reproductive development, and life span
-
Gerisch B., Weitzel C., Kober-Eisermann C., Rottiers V., Antebi A. A hormonal signaling pathway influencing C. elegans metabolism, reproductive development, and life span. Developmental Cell 2001, 1:841-851.
-
(2001)
Developmental Cell
, vol.1
, pp. 841-851
-
-
Gerisch, B.1
Weitzel, C.2
Kober-Eisermann, C.3
Rottiers, V.4
Antebi, A.5
-
31
-
-
0347761358
-
Expression and function of conserved nuclear receptor genes in Caenorhabditis elegans
-
Gissendanner C.R., Crossgrove K., Kraus K.A., Maina C.V., Sluder A.E. Expression and function of conserved nuclear receptor genes in Caenorhabditis elegans. Developmental Biology 2004, 266:399-416.
-
(2004)
Developmental Biology
, vol.266
, pp. 399-416
-
-
Gissendanner, C.R.1
Crossgrove, K.2
Kraus, K.A.3
Maina, C.V.4
Sluder, A.E.5
-
32
-
-
0034192430
-
Nhr-25, the Caenorhabditis elegans ortholog of ftz-f1, is required for epidermal and somatic gonad development
-
Gissendanner C.R., Sluder A.E. nhr-25, the Caenorhabditis elegans ortholog of ftz-f1, is required for epidermal and somatic gonad development. Developmental Biology 2000, 221:259-272.
-
(2000)
Developmental Biology
, vol.221
, pp. 259-272
-
-
Gissendanner, C.R.1
Sluder, A.E.2
-
33
-
-
0021418719
-
The C. elegans dauer larva: Developmental effects of pheromone, food, and temperature
-
Golden J.W., Riddle D.L. The C. elegans dauer larva: Developmental effects of pheromone, food, and temperature. Developmental Biology 1984, 102:368-378.
-
(1984)
Developmental Biology
, vol.102
, pp. 368-378
-
-
Golden, J.W.1
Riddle, D.L.2
-
34
-
-
79953683136
-
Fatty acid desaturation links germ cell loss to longevity through NHR-80/HNF4 in C. elegans
-
Goudeau J., Bellemin S., Toselli-Mollereau E., Shamalnasab M., Chen Y., Aguilaniu H. Fatty acid desaturation links germ cell loss to longevity through NHR-80/HNF4 in C. elegans. PLoS Biology 2011, 9:e1000599.
-
(2011)
PLoS Biology
, vol.9
-
-
Goudeau, J.1
Bellemin, S.2
Toselli-Mollereau, E.3
Shamalnasab, M.4
Chen, Y.5
Aguilaniu, H.6
-
35
-
-
78049437320
-
PER2 controls lipid metabolism by direct regulation of PPARgamma
-
Grimaldi B., Bellet M.M., Katada S., Astarita G., Hirayama J., Amin R.H., et al. PER2 controls lipid metabolism by direct regulation of PPARgamma. Cell Metabolism 2010, 12:509-520.
-
(2010)
Cell Metabolism
, vol.12
, pp. 509-520
-
-
Grimaldi, B.1
Bellet, M.M.2
Katada, S.3
Astarita, G.4
Hirayama, J.5
Amin, R.H.6
-
36
-
-
17844364875
-
Genes and mechanisms related to RNA interference regulate expression of the small temporal RNAs that control C. elegans developmental timing
-
Grishok A., Pasquinelli A.E., Conte D., Li N., Parrish S., Ha I., et al. Genes and mechanisms related to RNA interference regulate expression of the small temporal RNAs that control C. elegans developmental timing. Cell 2001, 106:23-34.
-
(2001)
Cell
, vol.106
, pp. 23-34
-
-
Grishok, A.1
Pasquinelli, A.E.2
Conte, D.3
Li, N.4
Parrish, S.5
Ha, I.6
-
37
-
-
14644398601
-
The temporal patterning microRNA let-7 regulates several transcription factors at the larval to adult transition in C. elegans
-
Grosshans H., Johnson T., Reinert K.L., Gerstein M., Slack F.J. The temporal patterning microRNA let-7 regulates several transcription factors at the larval to adult transition in C. elegans. Developmental Cell 2005, 8:321-330.
-
(2005)
Developmental Cell
, vol.8
, pp. 321-330
-
-
Grosshans, H.1
Johnson, T.2
Reinert, K.L.3
Gerstein, M.4
Slack, F.J.5
-
38
-
-
84864390119
-
Oestrogen-dependent regulation of miRNA biogenesis: many ways to skin the cat
-
Gupta A., Caffrey E., Callagy G., Gupta S. Oestrogen-dependent regulation of miRNA biogenesis: many ways to skin the cat. Biochemical Society Transactions 2012, 40:752-758.
-
(2012)
Biochemical Society Transactions
, vol.40
, pp. 752-758
-
-
Gupta, A.1
Caffrey, E.2
Callagy, G.3
Gupta, S.4
-
39
-
-
77955270654
-
The nuclear receptor gene nhr-25 plays multiple roles in the Caenorhabditis elegans heterochronic gene network to control the larva-to-adult transition
-
Hada K., Asahina M., Hasegawa H., Kanaho Y., Slack F.J., Niwa R. The nuclear receptor gene nhr-25 plays multiple roles in the Caenorhabditis elegans heterochronic gene network to control the larva-to-adult transition. Developmental Biology 2010, 344(2):1100-1109.
-
(2010)
Developmental Biology
, vol.344
, Issue.2
, pp. 1100-1109
-
-
Hada, K.1
Asahina, M.2
Hasegawa, H.3
Kanaho, Y.4
Slack, F.J.5
Niwa, R.6
-
40
-
-
73249148097
-
A feedback circuit involving let-7-family miRNAs and DAF-12 integrates environmental signals and developmental timing in Caenorhabditis elegans
-
Hammell C.M., Karp X., Ambros V. A feedback circuit involving let-7-family miRNAs and DAF-12 integrates environmental signals and developmental timing in Caenorhabditis elegans. Proceedings of the National Academy of Sciences of the United States of America 2009, 106:18668-18673.
-
(2009)
Proceedings of the National Academy of Sciences of the United States of America
, vol.106
, pp. 18668-18673
-
-
Hammell, C.M.1
Karp, X.2
Ambros, V.3
-
41
-
-
61349169058
-
Nhl-2 Modulates microRNA activity in Caenorhabditis elegans
-
Hammell C.M., Lubin I., Boag P.R., Blackwell T.K., Ambros V. nhl-2 Modulates microRNA activity in Caenorhabditis elegans. Cell 2009, 136:926-938.
-
(2009)
Cell
, vol.136
, pp. 926-938
-
-
Hammell, C.M.1
Lubin, I.2
Boag, P.R.3
Blackwell, T.K.4
Ambros, V.5
-
42
-
-
84872138910
-
Reproduction, fat metabolism, and life span: What is the connection?
-
Hansen M., Flatt T., Aguilaniu H. Reproduction, fat metabolism, and life span: What is the connection?. Cell Metabolism 2013, 17(1):10-19.
-
(2013)
Cell Metabolism
, vol.17
, Issue.1
, pp. 10-19
-
-
Hansen, M.1
Flatt, T.2
Aguilaniu, H.3
-
43
-
-
33846085944
-
The mir-84 and let-7 paralogous microRNA genes of Caenorhabditis elegans direct the cessation of molting via the conserved nuclear hormone receptors NHR-23 and NHR-25
-
Hayes G.D., Frand A.R., Ruvkun G. The mir-84 and let-7 paralogous microRNA genes of Caenorhabditis elegans direct the cessation of molting via the conserved nuclear hormone receptors NHR-23 and NHR-25. Development 2006, 133(23):4631-4641.
-
(2006)
Development
, vol.133
, Issue.23
, pp. 4631-4641
-
-
Hayes, G.D.1
Frand, A.R.2
Ruvkun, G.3
-
44
-
-
66649090056
-
Genome-wide association studies identify loci associated with age at menarche and age at natural menopause
-
He C., Kraft P., Chen C., Buring J.E., Pare G., Hankinson S.E., et al. Genome-wide association studies identify loci associated with age at menarche and age at natural menopause. Nature Genetics 2009, 41:724-728.
-
(2009)
Nature Genetics
, vol.41
, pp. 724-728
-
-
He, C.1
Kraft, P.2
Chen, C.3
Buring, J.E.4
Pare, G.5
Hankinson, S.E.6
-
45
-
-
0021994541
-
Polyploid tissues in the nematode C. elegans
-
Hedgecock E.M., White J.G. Polyploid tissues in the nematode C. elegans. Developmental Biology 1985, 107:128-133.
-
(1985)
Developmental Biology
, vol.107
, pp. 128-133
-
-
Hedgecock, E.M.1
White, J.G.2
-
46
-
-
79960937846
-
DAF-12 regulates a connected network of genes to ensure robust developmental decisions
-
Hochbaum D., Zhang Y., Stuckenholz C., Labhart P., Alexiadis V., Martin R., et al. DAF-12 regulates a connected network of genes to ensure robust developmental decisions. PLoS Genetics 2011, 7(7):e1002179.
-
(2011)
PLoS Genetics
, vol.7
, Issue.7
-
-
Hochbaum, D.1
Zhang, Y.2
Stuckenholz, C.3
Labhart, P.4
Alexiadis, V.5
Martin, R.6
-
47
-
-
33846923049
-
APL-1, a Caenorhabditis elegans protein related to the human beta-amyloid precursor protein, is essential for viability
-
Hornsten A., Lieberthal J., Fadia S., Malins R., Ha L., Xu X., et al. APL-1, a Caenorhabditis elegans protein related to the human beta-amyloid precursor protein, is essential for viability. Proceedings of the National Academy of Sciences of the United States of America 2007, 104(6):1971-1976.
-
(2007)
Proceedings of the National Academy of Sciences of the United States of America
, vol.104
, Issue.6
, pp. 1971-1976
-
-
Hornsten, A.1
Lieberthal, J.2
Fadia, S.3
Malins, R.4
Ha, L.5
Xu, X.6
-
48
-
-
0033609291
-
Signals from the reproductive system regulate the lifespan of C. elegans
-
Hsin H., Kenyon C. Signals from the reproductive system regulate the lifespan of C. elegans. Nature 1999, 399:362-366.
-
(1999)
Nature
, vol.399
, pp. 362-366
-
-
Hsin, H.1
Kenyon, C.2
-
49
-
-
0033527724
-
Similarity of the C. elegans developmental timing protein LIN-42 to circadian rhythm proteins
-
Jeon M., Gardner H.F., Miller E.A., Deshler J., Rougvie A.E. Similarity of the C. elegans developmental timing protein LIN-42 to circadian rhythm proteins. Science 1999, 286:1141-1146.
-
(1999)
Science
, vol.286
, pp. 1141-1146
-
-
Jeon, M.1
Gardner, H.F.2
Miller, E.A.3
Deshler, J.4
Rougvie, A.E.5
-
50
-
-
0036333147
-
DAF-9, a cytochrome P450 regulating C. elegans larval development and adult longevity
-
Jia K., Albert P.S., Riddle D.L. DAF-9, a cytochrome P450 regulating C. elegans larval development and adult longevity. Development 2002, 129(1):221-231.
-
(2002)
Development
, vol.129
, Issue.1
, pp. 221-231
-
-
Jia, K.1
Albert, P.S.2
Riddle, D.L.3
-
51
-
-
84861406978
-
Dauer larva quiescence alters the circuitry of microRNA pathways regulating cell fate progression in C. elegans
-
Karp X., Ambros V. Dauer larva quiescence alters the circuitry of microRNA pathways regulating cell fate progression in C. elegans. Development 2012, 139:2177-2186.
-
(2012)
Development
, vol.139
, pp. 2177-2186
-
-
Karp, X.1
Ambros, V.2
-
52
-
-
67349140353
-
Premature aging in vitamin D receptor mutant mice
-
Keisala T., Minasyan A., Lou Y.R., Zou J., Kalueff A.V., Pyykko I., et al. Premature aging in vitamin D receptor mutant mice. In J Steroid Biochem Mol Biol 2009, 115(3-5):91-97.
-
(2009)
In J Steroid Biochem Mol Biol
, vol.115
, Issue.3-5
, pp. 91-97
-
-
Keisala, T.1
Minasyan, A.2
Lou, Y.R.3
Zou, J.4
Kalueff, A.V.5
Pyykko, I.6
-
53
-
-
77950200010
-
The genetics of ageing
-
Kenyon C.J. The genetics of ageing. Nature 2010, 464:504-512.
-
(2010)
Nature
, vol.464
, pp. 504-512
-
-
Kenyon, C.J.1
-
54
-
-
0030813398
-
Daf-2, an insulin receptor-like gene that regulates longevity and diapause in Caenorhabditis elegans
-
Kimura K.D., Tissenbaum H.A., Liu Y., Ruvkun G. daf-2, an insulin receptor-like gene that regulates longevity and diapause in Caenorhabditis elegans. Science 1997, 277:942-946.
-
(1997)
Science
, vol.277
, pp. 942-946
-
-
Kimura, K.D.1
Tissenbaum, H.A.2
Liu, Y.3
Ruvkun, G.4
-
55
-
-
0035912840
-
Nuclear hormone receptor CHR3 is a critical regulator of all four larval molts of the nematode Caenorhabditis elegans
-
Kostrouchova M., Krause M., Kostrouch Z., Rall J.E. Nuclear hormone receptor CHR3 is a critical regulator of all four larval molts of the nematode Caenorhabditis elegans. Proceedings of the National Academy of Sciences of the United States of America 2001, 98:7360-7365.
-
(2001)
Proceedings of the National Academy of Sciences of the United States of America
, vol.98
, pp. 7360-7365
-
-
Kostrouchova, M.1
Krause, M.2
Kostrouch, Z.3
Rall, J.E.4
-
56
-
-
13544263313
-
Structural analyses reveal phosphatidyl inositols as ligands for the NR5 orphan receptors SF-1 and LRH-1
-
Krylova I.N., Sablin E.P., Moore J., Xu R.X., Waitt G.M., MacKay J.A., et al. Structural analyses reveal phosphatidyl inositols as ligands for the NR5 orphan receptors SF-1 and LRH-1. Cell 2005, 120:343-355.
-
(2005)
Cell
, vol.120
, pp. 343-355
-
-
Krylova, I.N.1
Sablin, E.P.2
Moore, J.3
Xu, R.X.4
Waitt, G.M.5
MacKay, J.A.6
-
57
-
-
84255206549
-
Cryptochromes mediate rhythmic repression of the glucocorticoid receptor
-
Lamia K.A., Papp S.J., Yu R.T., Barish G.D., Uhlenhaut N.H., Jonker J.W., et al. Cryptochromes mediate rhythmic repression of the glucocorticoid receptor. Nature 2011, 480:552-556.
-
(2011)
Nature
, vol.480
, pp. 552-556
-
-
Lamia, K.A.1
Papp, S.J.2
Yu, R.T.3
Barish, G.D.4
Uhlenhaut, N.H.5
Jonker, J.W.6
-
58
-
-
80053312481
-
Autophagy and lipid metabolism coordinately modulate life span in germline-less C. elegans
-
Lapierre L.R., Gelino S., Melendez A., Hansen M. Autophagy and lipid metabolism coordinately modulate life span in germline-less C. elegans. Current Biology 2011, 21:1507-1514.
-
(2011)
Current Biology
, vol.21
, pp. 1507-1514
-
-
Lapierre, L.R.1
Gelino, S.2
Melendez, A.3
Hansen, M.4
-
59
-
-
0027751663
-
The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14
-
Lee R.C., Feinbaum R.L., Ambros V. The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14. Cell 1993, 75:843-854.
-
(1993)
Cell
, vol.75
, pp. 843-854
-
-
Lee, R.C.1
Feinbaum, R.L.2
Ambros, V.3
-
60
-
-
79959560633
-
A nuclear-receptor-dependent phosphatidylcholine pathway with antidiabetic effects
-
Lee J.M., Lee Y.K., Mamrosh J.L., Busby S.A., Griffin P.R., Pathak M.C., et al. A nuclear-receptor-dependent phosphatidylcholine pathway with antidiabetic effects. Nature 2011, 474:506-510.
-
(2011)
Nature
, vol.474
, pp. 506-510
-
-
Lee, J.M.1
Lee, Y.K.2
Mamrosh, J.L.3
Busby, S.A.4
Griffin, P.R.5
Pathak, M.C.6
-
61
-
-
10344229417
-
NCR-1 and NCR-2, the C. elegans homologs of the human Niemann-Pick type C1 disease protein, function upstream of DAF-9 in the dauer formation pathways
-
Li J., Brown G., Ailion M., Lee S., Thomas J.H. NCR-1 and NCR-2, the C. elegans homologs of the human Niemann-Pick type C1 disease protein, function upstream of DAF-9 in the dauer formation pathways. Development 2004, 131:5741-5752.
-
(2004)
Development
, vol.131
, pp. 5741-5752
-
-
Li, J.1
Brown, G.2
Ailion, M.3
Lee, S.4
Thomas, J.H.5
-
62
-
-
0037380570
-
Daf-28 encodes a C. elegans insulin superfamily member that is regulated by environmental cues and acts in the DAF-2 signaling pathway
-
Li W., Kennedy S.G., Ruvkun G. daf-28 encodes a C. elegans insulin superfamily member that is regulated by environmental cues and acts in the DAF-2 signaling pathway. Genes & Development 2003, 17:844-858.
-
(2003)
Genes & Development
, vol.17
, pp. 844-858
-
-
Li, W.1
Kennedy, S.G.2
Ruvkun, G.3
-
63
-
-
0030657540
-
Daf-16: An HNF-3/forkhead family member that can function to double the life-span of Caenorhabditis elegans
-
Lin K., Dorman J.B., Rodan A., Kenyon C. daf-16: An HNF-3/forkhead family member that can function to double the life-span of Caenorhabditis elegans. Science 1997, 278:1319-1322.
-
(1997)
Science
, vol.278
, pp. 1319-1322
-
-
Lin, K.1
Dorman, J.B.2
Rodan, A.3
Kenyon, C.4
-
64
-
-
0025764348
-
Alternative temporal control systems for hypodermal cell differentiation in C. elegans
-
Liu Z., Ambros V. Alternative temporal control systems for hypodermal cell differentiation in C. elegans. Nature 1991, 350:162-165.
-
(1991)
Nature
, vol.350
, pp. 162-165
-
-
Liu, Z.1
Ambros, V.2
-
65
-
-
4444304350
-
A novel nuclear receptor/coregulator complex controls C. elegans lipid metabolism, larval development, and aging
-
Ludewig A.H., Kober-Eisermann C., Weitzel C., Bethke A., Neubert K., Gerisch B., et al. A novel nuclear receptor/coregulator complex controls C. elegans lipid metabolism, larval development, and aging. Genes & Development 2004, 18:2120-2133.
-
(2004)
Genes & Development
, vol.18
, pp. 2120-2133
-
-
Ludewig, A.H.1
Kober-Eisermann, C.2
Weitzel, C.3
Bethke, A.4
Neubert, K.5
Gerisch, B.6
-
66
-
-
2342428206
-
Intercellular signaling of reproductive development by the C. elegans DAF-9 cytochrome P450
-
Mak H.Y., Ruvkun G. Intercellular signaling of reproductive development by the C. elegans DAF-9 cytochrome P450. Development 2004, 131:1777-1786.
-
(2004)
Development
, vol.131
, pp. 1777-1786
-
-
Mak, H.Y.1
Ruvkun, G.2
-
67
-
-
58049208169
-
The let-7 microRNA target gene, Mlin41/Trim71 is required for mouse embryonic survival and neural tube closure
-
Maller Schulman B.R., Liang X., Stahlhut C., DelConte C., Stefani G., Slack F.J. The let-7 microRNA target gene, Mlin41/Trim71 is required for mouse embryonic survival and neural tube closure. Cell Cycle 2008, 7:3935-3942.
-
(2008)
Cell Cycle
, vol.7
, pp. 3935-3942
-
-
Maller Schulman, B.R.1
Liang, X.2
Stahlhut, C.3
DelConte, C.4
Stefani, G.5
Slack, F.J.6
-
68
-
-
0029562554
-
The RXR heterodimers and orphan receptors
-
Mangelsdorf D.J., Evans R.M. The RXR heterodimers and orphan receptors. Cell 1995, 83:841-850.
-
(1995)
Cell
, vol.83
, pp. 841-850
-
-
Mangelsdorf, D.J.1
Evans, R.M.2
-
69
-
-
0012473279
-
The nuclear receptor superfamily: The second decade
-
Mangelsdorf D.J., Thummel C., Beato M., Herrlich P., Schutz G., Umesono K., et al. The nuclear receptor superfamily: The second decade. Cell 1995, 83:835-839.
-
(1995)
Cell
, vol.83
, pp. 835-839
-
-
Mangelsdorf, D.J.1
Thummel, C.2
Beato, M.3
Herrlich, P.4
Schutz, G.5
Umesono, K.6
-
70
-
-
8844266121
-
Sterol-derived hormone(s) controls entry into diapause in Caenorhabditis elegans by consecutive activation of DAF-12 and DAF-16
-
Matyash V., Entchev E.V., Mende F., Wilsch-Brauninger M., Thiele C., Schmidt A.W., et al. Sterol-derived hormone(s) controls entry into diapause in Caenorhabditis elegans by consecutive activation of DAF-12 and DAF-16. PLoS Biology 2004, 2:e280.
-
(2004)
PLoS Biology
, vol.2
-
-
Matyash, V.1
Entchev, E.V.2
Mende, F.3
Wilsch-Brauninger, M.4
Thiele, C.5
Schmidt, A.W.6
-
71
-
-
84858341125
-
New genes that extend Caenorhabditis elegans' lifespan in response to reproductive signals
-
McCormick M., Chen K., Ramaswamy P., Kenyon C. New genes that extend Caenorhabditis elegans' lifespan in response to reproductive signals. Aging Cell 2012, 11:192-202.
-
(2012)
Aging Cell
, vol.11
, pp. 192-202
-
-
McCormick, M.1
Chen, K.2
Ramaswamy, P.3
Kenyon, C.4
-
72
-
-
34248233488
-
Differential gene expression of Caenorhabditis elegans grown on unmethylated sterols or 4alpha-methylsterols
-
Merris M., Wang T., Soteropoulos P., Lenard J. Differential gene expression of Caenorhabditis elegans grown on unmethylated sterols or 4alpha-methylsterols. Journal of Lipid Research 2007, 48:1159-1166.
-
(2007)
Journal of Lipid Research
, vol.48
, pp. 1159-1166
-
-
Merris, M.1
Wang, T.2
Soteropoulos, P.3
Lenard, J.4
-
73
-
-
81155127507
-
Pkc-1 regulates daf-2 insulin/IGF signalling-dependent control of dauer formation in Caenorhabditis elegans
-
Monje J.M., Brokate-Llanos A.M., Perez-Jimenez M.M., Fidalgo M.A., Munoz M.J. pkc-1 regulates daf-2 insulin/IGF signalling-dependent control of dauer formation in Caenorhabditis elegans. Aging Cell 2011, 10:1021-1031.
-
(2011)
Aging Cell
, vol.10
, pp. 1021-1031
-
-
Monje, J.M.1
Brokate-Llanos, A.M.2
Perez-Jimenez, M.M.3
Fidalgo, M.A.4
Munoz, M.J.5
-
74
-
-
84155171260
-
LIN-42/PERIOD controls cyclical and developmental progression of C. elegans molts
-
Monsalve G.C., Van Buskirk C., Frand A.R. LIN-42/PERIOD controls cyclical and developmental progression of C. elegans molts. Current Biology 2011, 21:2033-2045.
-
(2011)
Current Biology
, vol.21
, pp. 2033-2045
-
-
Monsalve, G.C.1
Van Buskirk, C.2
Frand, A.R.3
-
75
-
-
34250364575
-
Liver X receptor alpha associates with human life span
-
Mooijaart S.P., Kuningas M., Westendorp R.G., Houwing-Duistermaat J.J., Slagboom P.E., Rensen P.C., et al. Liver X receptor alpha associates with human life span. The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences 2007, 62:343-349.
-
(2007)
The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences
, vol.62
, pp. 343-349
-
-
Mooijaart, S.P.1
Kuningas, M.2
Westendorp, R.G.3
Houwing-Duistermaat, J.J.4
Slagboom, P.E.5
Rensen, P.C.6
-
76
-
-
33845709215
-
Multiple mechanisms are involved in regulating the expression of the developmental timing regulator lin-28 in Caenorhabditis elegans
-
Morita K., Han M. Multiple mechanisms are involved in regulating the expression of the developmental timing regulator lin-28 in Caenorhabditis elegans. EMBO Journal 2006, 25:5794-5804.
-
(2006)
EMBO Journal
, vol.25
, pp. 5794-5804
-
-
Morita, K.1
Han, M.2
-
77
-
-
0029768753
-
A phosphatidylinositol-3-OH kinase family member regulating longevity and diapause in Caenorhabditis elegans
-
Morris J.Z., Tissenbaum H.A., Ruvkun G. A phosphatidylinositol-3-OH kinase family member regulating longevity and diapause in Caenorhabditis elegans. Nature 1996, 382:536-539.
-
(1996)
Nature
, vol.382
, pp. 536-539
-
-
Morris, J.Z.1
Tissenbaum, H.A.2
Ruvkun, G.3
-
78
-
-
0030970775
-
The cold shock domain protein LIN-28 controls developmental timing in C. elegans and is regulated by the lin-4 RNA
-
Moss E.G., Lee R.C., Ambros V. The cold shock domain protein LIN-28 controls developmental timing in C. elegans and is regulated by the lin-4 RNA. Cell 1997, 88:637-646.
-
(1997)
Cell
, vol.88
, pp. 637-646
-
-
Moss, E.G.1
Lee, R.C.2
Ambros, V.3
-
79
-
-
33646042547
-
Identification of ligands for DAF-12 that govern dauer formation and reproduction in C. elegans
-
Motola D.L., Cummins C.L., Rottiers V., Sharma K.K., Li T., Li Y., et al. Identification of ligands for DAF-12 that govern dauer formation and reproduction in C. elegans. Cell 2006, 124:1209-1223.
-
(2006)
Cell
, vol.124
, pp. 1209-1223
-
-
Motola, D.L.1
Cummins, C.L.2
Rottiers, V.3
Sharma, K.K.4
Li, T.5
Li, Y.6
-
80
-
-
77957675740
-
Regulation of C. elegans fat uptake and storage by acyl-CoA synthase-3 is dependent on NR5A family nuclear hormone receptor nhr-25
-
Mullaney B.C., Blind R.D., Lemieux G.A., Perez C.L., Elle I.C., Faergeman N.J., et al. Regulation of C. elegans fat uptake and storage by acyl-CoA synthase-3 is dependent on NR5A family nuclear hormone receptor nhr-25. Cell Metabolism 2010, 12:398-410.
-
(2010)
Cell Metabolism
, vol.12
, pp. 398-410
-
-
Mullaney, B.C.1
Blind, R.D.2
Lemieux, G.A.3
Perez, C.L.4
Elle, I.C.5
Faergeman, N.J.6
-
81
-
-
40149088267
-
The expression of the Alzheimer's amyloid precursor protein-like gene is regulated by developmental timing microRNAs and their targets in Caenorhabditis elegans
-
Niwa R., Zhou F., Li C., Slack F.J. The expression of the Alzheimer's amyloid precursor protein-like gene is regulated by developmental timing microRNAs and their targets in Caenorhabditis elegans. Developmental Biology 2008, 315:418-425.
-
(2008)
Developmental Biology
, vol.315
, pp. 418-425
-
-
Niwa, R.1
Zhou, F.2
Li, C.3
Slack, F.J.4
-
82
-
-
58149145422
-
A conserved endocrine mechanism controls the formation of dauer and infective larvae in nematodes
-
Ogawa A., Streit A., Antebi A., Sommer R.J. A conserved endocrine mechanism controls the formation of dauer and infective larvae in nematodes. Current Biology 2009, 19:67-71.
-
(2009)
Current Biology
, vol.19
, pp. 67-71
-
-
Ogawa, A.1
Streit, A.2
Antebi, A.3
Sommer, R.J.4
-
83
-
-
0030659557
-
The Fork head transcription factor DAF-16 transduces insulin-like metabolic and longevity signals in C. elegans
-
Ogg S., Paradis S., Gottlieb S., Patterson G.I., Lee L., Tissenbaum H.A., et al. The Fork head transcription factor DAF-16 transduces insulin-like metabolic and longevity signals in C. elegans. Nature 1997, 389:994-999.
-
(1997)
Nature
, vol.389
, pp. 994-999
-
-
Ogg, S.1
Paradis, S.2
Gottlieb, S.3
Patterson, G.I.4
Lee, L.5
Tissenbaum, H.A.6
-
84
-
-
66649105485
-
Genetic variation in LIN28B is associated with the timing of puberty
-
Ong K.K., Elks C.E., Li S., Zhao J.H., Luan J., Andersen L.B., et al. Genetic variation in LIN28B is associated with the timing of puberty. Nature Genetics 2009, 41:729-733.
-
(2009)
Nature Genetics
, vol.41
, pp. 729-733
-
-
Ong, K.K.1
Elks, C.E.2
Li, S.3
Zhao, J.H.4
Luan, J.5
Andersen, L.B.6
-
85
-
-
0032529189
-
C. elegans Akt/PKB transduces insulin receptor-like signals from AGE-1 PI3 kinase to the DAF-16 transcription factor
-
Paradis S., Ruvkun G. C. elegans Akt/PKB transduces insulin receptor-like signals from AGE-1 PI3 kinase to the DAF-16 transcription factor. Genes & Development 1998, 12:2488-2498.
-
(1998)
Genes & Development
, vol.12
, pp. 2488-2498
-
-
Paradis, S.1
Ruvkun, G.2
-
86
-
-
48249142372
-
Genetic identification of HSD-1, a conserved steroidogenic enzyme that directs larval development in Caenorhabditis elegans
-
Patel D.S., Fang L.L., Svy D.K., Ruvkun G., Li W. Genetic identification of HSD-1, a conserved steroidogenic enzyme that directs larval development in Caenorhabditis elegans. Development 2008, 135:2239-2249.
-
(2008)
Development
, vol.135
, pp. 2239-2249
-
-
Patel, D.S.1
Fang, L.L.2
Svy, D.K.3
Ruvkun, G.4
Li, W.5
-
87
-
-
0030776478
-
The DAF-3 Smad protein antagonizes TGF-beta-related receptor signaling in the Caenorhabditis elegans dauer pathway
-
Patterson G.I., Koweek A., Wong A., Liu Y., Ruvkun G. The DAF-3 Smad protein antagonizes TGF-beta-related receptor signaling in the Caenorhabditis elegans dauer pathway. Genes & Development 1997, 11:2679-2690.
-
(1997)
Genes & Development
, vol.11
, pp. 2679-2690
-
-
Patterson, G.I.1
Koweek, A.2
Wong, A.3
Liu, Y.4
Ruvkun, G.5
-
88
-
-
2542563401
-
The C. elegans heterochronic gene lin-46 affects developmental timing at two larval stages and encodes a relative of the scaffolding protein gephyrin
-
Pepper A.S., McCane J.E., Kemper K., Yeung D.A., Lee R.C., Ambros V., et al. The C. elegans heterochronic gene lin-46 affects developmental timing at two larval stages and encodes a relative of the scaffolding protein gephyrin. Development 2004, 131:2049-2059.
-
(2004)
Development
, vol.131
, pp. 2049-2059
-
-
Pepper, A.S.1
McCane, J.E.2
Kemper, K.3
Yeung, D.A.4
Lee, R.C.5
Ambros, V.6
-
89
-
-
84864026646
-
The interplay between retinoic acid receptor-related orphan receptors and human diseases
-
Ranhotra H.S. The interplay between retinoic acid receptor-related orphan receptors and human diseases. Journal of Receptor and Signal Transduction Research 2012, 32:181-189.
-
(2012)
Journal of Receptor and Signal Transduction Research
, vol.32
, pp. 181-189
-
-
Ranhotra, H.S.1
-
90
-
-
0034708122
-
The 21-nucleotide let-7 RNA regulates developmental timing in Caenorhabditis elegans
-
Reinhart B.J., Slack F.J., Basson M., Pasquinelli A.E., Bettinger J.C., Rougvie A.E., et al. The 21-nucleotide let-7 RNA regulates developmental timing in Caenorhabditis elegans. Nature 2000, 403:901-906.
-
(2000)
Nature
, vol.403
, pp. 901-906
-
-
Reinhart, B.J.1
Slack, F.J.2
Basson, M.3
Pasquinelli, A.E.4
Bettinger, J.C.5
Rougvie, A.E.6
-
91
-
-
10544256181
-
Control of C. elegans larval development by neuronal expression of a TGF-beta homolog
-
Ren P., Lim C.S., Johnsen R., Albert P.S., Pilgrim D., Riddle D.L. Control of C. elegans larval development by neuronal expression of a TGF-beta homolog. Science 1996, 274:1389-1391.
-
(1996)
Science
, vol.274
, pp. 1389-1391
-
-
Ren, P.1
Lim, C.S.2
Johnsen, R.3
Albert, P.S.4
Pilgrim, D.5
Riddle, D.L.6
-
92
-
-
0019496482
-
Interacting genes in nematode dauer larva formation
-
Riddle D.L., Swanson M.M., Albert P.S. Interacting genes in nematode dauer larva formation. Nature 1981, 290:668-671.
-
(1981)
Nature
, vol.290
, pp. 668-671
-
-
Riddle, D.L.1
Swanson, M.M.2
Albert, P.S.3
-
93
-
-
33645527191
-
Hormonal control of C. elegans dauer formation and life span by a Rieske-like oxygenase
-
Rottiers V., Motola D.L., Gerisch B., Cummins C.L., Nishiwaki K., Mangelsdorf D.J., et al. Hormonal control of C. elegans dauer formation and life span by a Rieske-like oxygenase. Developmental Cell 2006, 10:473-482.
-
(2006)
Developmental Cell
, vol.10
, pp. 473-482
-
-
Rottiers, V.1
Motola, D.L.2
Gerisch, B.3
Cummins, C.L.4
Nishiwaki, K.5
Mangelsdorf, D.J.6
-
94
-
-
0037790917
-
The enzymes, regulation, and genetics of bile acid synthesis
-
Russell D.W. The enzymes, regulation, and genetics of bile acid synthesis. Annual Review of Biochemistry 2003, 72:137-174.
-
(2003)
Annual Review of Biochemistry
, vol.72
, pp. 137-174
-
-
Russell, D.W.1
-
95
-
-
48649103982
-
A feedback loop comprising lin-28 and let-7 controls pre-let-7 maturation during neural stem-cell commitment
-
Rybak A., Fuchs H., Smirnova L., Brandt C., Pohl E.E., Nitsch R., et al. A feedback loop comprising lin-28 and let-7 controls pre-let-7 maturation during neural stem-cell commitment. Nature Cell Biology 2008, 10:987-993.
-
(2008)
Nature Cell Biology
, vol.10
, pp. 987-993
-
-
Rybak, A.1
Fuchs, H.2
Smirnova, L.3
Brandt, C.4
Pohl, E.E.5
Nitsch, R.6
-
96
-
-
84859956529
-
Hormonal signal amplification mediates environmental conditions during development and controls an irreversible commitment to adulthood
-
Schaedel O.N., Gerisch B., Antebi A., Sternberg P.W. Hormonal signal amplification mediates environmental conditions during development and controls an irreversible commitment to adulthood. PLoS Biology 2012, 10:e1001306.
-
(2012)
PLoS Biology
, vol.10
-
-
Schaedel, O.N.1
Gerisch, B.2
Antebi, A.3
Sternberg, P.W.4
-
97
-
-
0037085968
-
Two genetic circuits repress the Caenorhabditis elegans heterochronic gene lin-28 after translation initiation
-
Seggerson K., Tang L., Moss E.G. Two genetic circuits repress the Caenorhabditis elegans heterochronic gene lin-28 after translation initiation. Developmental Biology 2002, 243:215-225.
-
(2002)
Developmental Biology
, vol.243
, pp. 215-225
-
-
Seggerson, K.1
Tang, L.2
Moss, E.G.3
-
98
-
-
84871101784
-
A steroid receptor-microRNA switch regulates life span in response to signals from the gonad
-
Shen Y., Wollam J., Magner D., Karalay O., Antebi A. A steroid receptor-microRNA switch regulates life span in response to signals from the gonad. Science 2012, 338:1472-1476.
-
(2012)
Science
, vol.338
, pp. 1472-1476
-
-
Shen, Y.1
Wollam, J.2
Magner, D.3
Karalay, O.4
Antebi, A.5
-
99
-
-
0033634943
-
The lin-41 RBCC gene acts in the C. elegans heterochronic pathway between the let-7 regulatory RNA and the LIN-29 transcription factor
-
Slack F.J., Basson M., Liu Z., Ambros V., Horvitz H.R., Ruvkun G. The lin-41 RBCC gene acts in the C. elegans heterochronic pathway between the let-7 regulatory RNA and the LIN-29 transcription factor. Molecular Cell 2000, 5:659-669.
-
(2000)
Molecular Cell
, vol.5
, pp. 659-669
-
-
Slack, F.J.1
Basson, M.2
Liu, Z.3
Ambros, V.4
Horvitz, H.R.5
Ruvkun, G.6
-
100
-
-
84886601180
-
Steroidogenesis in the skin: Implications for local immune functions
-
Slominski A., Zbytek B., Nikolakis G., Manna P.R., Skobowiat C., Zmijewski M., et al. Steroidogenesis in the skin: Implications for local immune functions. The Journal of Steroid Biochemistry and Molecular Biology 2013, 67:123-128.
-
(2013)
The Journal of Steroid Biochemistry and Molecular Biology
, vol.67
, pp. 123-128
-
-
Slominski, A.1
Zbytek, B.2
Nikolakis, G.3
Manna, P.R.4
Skobowiat, C.5
Zmijewski, M.6
-
101
-
-
66649116283
-
Genome-wide association study identifies sequence variants on 6q21 associated with age at menarche
-
Sulem P., Gudbjartsson D.F., Rafnar T., Holm H., Olafsdottir E.J., Olafsdottir G.H., et al. Genome-wide association study identifies sequence variants on 6q21 associated with age at menarche. Nature Genetics 2009, 41:734-738.
-
(2009)
Nature Genetics
, vol.41
, pp. 734-738
-
-
Sulem, P.1
Gudbjartsson, D.F.2
Rafnar, T.3
Holm, H.4
Olafsdottir, E.J.5
Olafsdottir, G.H.6
-
102
-
-
0017618537
-
Post-embryonic cell lineages of the nematode, C. elegans
-
Sulston J.E., Horvitz H.R. Post-embryonic cell lineages of the nematode, C. elegans. Developmental Biology 1977, 56:110-156.
-
(1977)
Developmental Biology
, vol.56
, pp. 110-156
-
-
Sulston, J.E.1
Horvitz, H.R.2
-
103
-
-
33747195353
-
Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors
-
Takahashi K., Yamanaka S. Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell 2006, 126:663-676.
-
(2006)
Cell
, vol.126
, pp. 663-676
-
-
Takahashi, K.1
Yamanaka, S.2
-
104
-
-
29144439248
-
Novel heterochronic functions of the Caenorhabditis elegans period-related protein LIN-42
-
Tennessen J.M., Gardner H.F., Volk M.L., Rougvie A.E. Novel heterochronic functions of the Caenorhabditis elegans period-related protein LIN-42. Developmental Biology 2006, 289:30-43.
-
(2006)
Developmental Biology
, vol.289
, pp. 30-43
-
-
Tennessen, J.M.1
Gardner, H.F.2
Volk, M.L.3
Rougvie, A.E.4
-
105
-
-
77957663525
-
The C. elegans developmental timing protein LIN-42 regulates diapause in response to environmental cues
-
Tennessen J.M., Opperman K.J., Rougvie A.E. The C. elegans developmental timing protein LIN-42 regulates diapause in response to environmental cues. Development 2010, 137:3501-3511.
-
(2010)
Development
, vol.137
, pp. 3501-3511
-
-
Tennessen, J.M.1
Opperman, K.J.2
Rougvie, A.E.3
-
106
-
-
80053315762
-
Coordinating growth and maturation-Insights from Drosophila
-
Tennessen J.M., Thummel C.S. Coordinating growth and maturation-Insights from Drosophila. Current Biology 2011, 21:R750-R757.
-
(2011)
Current Biology
, vol.21
-
-
Tennessen, J.M.1
Thummel, C.S.2
-
107
-
-
84872074745
-
Identification of microRNA-98 as a therapeutic target inhibiting prostate cancer growth and a biomarker induced by vitamin D
-
Ting H.J., Messing J., Yasmin-Karim S., Lee Y.F. Identification of microRNA-98 as a therapeutic target inhibiting prostate cancer growth and a biomarker induced by vitamin D. Journal of Biological Chemistry 2013, 288:1-9.
-
(2013)
Journal of Biological Chemistry
, vol.288
, pp. 1-9
-
-
Ting, H.J.1
Messing, J.2
Yasmin-Karim, S.3
Lee, Y.F.4
-
108
-
-
33847011721
-
Steroidogenic factor-1 is a sphingolipid binding protein
-
Urs A.N., Dammer E., Kelly S., Wang E., Merrill A.H., Sewer M.B. Steroidogenic factor-1 is a sphingolipid binding protein. Molecular and Cellular Endocrinology 2007, 265-266:174-178.
-
(2007)
Molecular and Cellular Endocrinology
, pp. 174-178
-
-
Urs, A.N.1
Dammer, E.2
Kelly, S.3
Wang, E.4
Merrill, A.H.5
Sewer, M.B.6
-
109
-
-
79952360425
-
LIN-28 co-transcriptionally binds primary let-7 to regulate miRNA maturation in Caenorhabditis elegans
-
Van Wynsberghe P.M., Kai Z.S., Massirer K.B., Burton V.H., Yeo G.W., Pasquinelli A.E. LIN-28 co-transcriptionally binds primary let-7 to regulate miRNA maturation in Caenorhabditis elegans. Nature Structural & Molecular Biology 2011, 18:302-308.
-
(2011)
Nature Structural & Molecular Biology
, vol.18
, pp. 302-308
-
-
Van Wynsberghe, P.M.1
Kai, Z.S.2
Massirer, K.B.3
Burton, V.H.4
Yeo, G.W.5
Pasquinelli, A.E.6
-
110
-
-
84866182143
-
RPN-6 determines C. elegans longevity under proteotoxic stress conditions
-
Vilchez D., Morantte I., Liu Z., Douglas P.M., Merkwirth C., Rodrigues A.P., et al. RPN-6 determines C. elegans longevity under proteotoxic stress conditions. Nature 2012, 489:263-268.
-
(2012)
Nature
, vol.489
, pp. 263-268
-
-
Vilchez, D.1
Morantte, I.2
Liu, Z.3
Douglas, P.M.4
Merkwirth, C.5
Rodrigues, A.P.6
-
111
-
-
40849108663
-
Selective blockade of microRNA processing by Lin28
-
Viswanathan S.R., Daley G.Q., Gregory R.I. Selective blockade of microRNA processing by Lin28. Science 2008, 320:97-100.
-
(2008)
Science
, vol.320
, pp. 97-100
-
-
Viswanathan, S.R.1
Daley, G.Q.2
Gregory, R.I.3
-
112
-
-
77951149298
-
Modulation of retinoic acid receptor-related orphan receptor alpha and gamma activity by 7-oxygenated sterol ligands
-
Wang Y., Kumar N., Solt L.A., Richardson T.I., Helvering L.M., Crumbley C., et al. Modulation of retinoic acid receptor-related orphan receptor alpha and gamma activity by 7-oxygenated sterol ligands. Journal of Biological Chemistry 2010, 285:5013-5025.
-
(2010)
Journal of Biological Chemistry
, vol.285
, pp. 5013-5025
-
-
Wang, Y.1
Kumar, N.2
Solt, L.A.3
Richardson, T.I.4
Helvering, L.M.5
Crumbley, C.6
-
113
-
-
55849101681
-
Fat metabolism links germline stem cells and longevity in C. elegans
-
Wang M.C., O'Rourke E.J., Ruvkun G. Fat metabolism links germline stem cells and longevity in C. elegans. Science 2008, 322:957-960.
-
(2008)
Science
, vol.322
, pp. 957-960
-
-
Wang, M.C.1
O'Rourke, E.J.2
Ruvkun, G.3
-
114
-
-
67249153259
-
Identification of the nuclear receptor DAF-12 as a therapeutic target in parasitic nematodes
-
Wang Z., Zhou X.E., Motola D.L., Gao X., Suino-Powell K., Conneely A., et al. Identification of the nuclear receptor DAF-12 as a therapeutic target in parasitic nematodes. Proceedings of the National Academy of Sciences of the United States of America 2009, 106:9138-9143.
-
(2009)
Proceedings of the National Academy of Sciences of the United States of America
, vol.106
, pp. 9138-9143
-
-
Wang, Z.1
Zhou, X.E.2
Motola, D.L.3
Gao, X.4
Suino-Powell, K.5
Conneely, A.6
-
115
-
-
77958478701
-
Intracellular trafficking and synaptic function of APL-1 in Caenorhabditis elegans
-
Wiese M., Antebi A., Zheng H. Intracellular trafficking and synaptic function of APL-1 in Caenorhabditis elegans. PLoS One 2010, 5(9):e12790.
-
(2010)
PLoS One
, vol.5
, Issue.9
-
-
Wiese, M.1
Antebi, A.2
Zheng, H.3
-
116
-
-
0027730383
-
Posttranscriptional regulation of the heterochronic gene lin-14 by lin-4 mediates temporal pattern formation in C. elegans
-
Wightman B., Ha I., Ruvkun G. Posttranscriptional regulation of the heterochronic gene lin-14 by lin-4 mediates temporal pattern formation in C. elegans. Cell 1993, 75:855-862.
-
(1993)
Cell
, vol.75
, pp. 855-862
-
-
Wightman, B.1
Ha, I.2
Ruvkun, G.3
-
117
-
-
84859991779
-
A novel 3-hydroxysteroid dehydrogenase that regulates reproductive development and longevity
-
Wollam J., Magner D.B., Magomedova L., Rass E., Shen Y., Rottiers V., et al. A novel 3-hydroxysteroid dehydrogenase that regulates reproductive development and longevity. PLoS Biology 2012, 10:e1001305.
-
(2012)
PLoS Biology
, vol.10
-
-
Wollam, J.1
Magner, D.B.2
Magomedova, L.3
Rass, E.4
Shen, Y.5
Rottiers, V.6
-
118
-
-
80052821900
-
The Rieske oxygenase DAF-36 functions as a cholesterol 7-desaturase in steroidogenic pathways governing longevity
-
Wollam J., Magomedova L., Magner D.B., Shen Y., Rottiers V., Motola D.L., et al. The Rieske oxygenase DAF-36 functions as a cholesterol 7-desaturase in steroidogenic pathways governing longevity. Aging Cell 2011, 10:879-884.
-
(2011)
Aging Cell
, vol.10
, pp. 879-884
-
-
Wollam, J.1
Magomedova, L.2
Magner, D.B.3
Shen, Y.4
Rottiers, V.5
Motola, D.L.6
-
119
-
-
84863992386
-
Let-7-complex microRNAs regulate the temporal identity of Drosophila mushroom body neurons via chinmo
-
Wu Y.C., Chen C.H., Mercer A., Sokol N.S. Let-7-complex microRNAs regulate the temporal identity of Drosophila mushroom body neurons via chinmo. Developmental Cell 2012, 23:202-209.
-
(2012)
Developmental Cell
, vol.23
, pp. 202-209
-
-
Wu, Y.C.1
Chen, C.H.2
Mercer, A.3
Sokol, N.S.4
-
120
-
-
67651119864
-
The temporally regulated transcription factor sel-7 controls developmental timing in C. elegans
-
Xia D., Huang X., Zhang H. The temporally regulated transcription factor sel-7 controls developmental timing in C. elegans. Developmental Biology 2009, 332:246-257.
-
(2009)
Developmental Biology
, vol.332
, pp. 246-257
-
-
Xia, D.1
Huang, X.2
Zhang, H.3
-
121
-
-
77956821042
-
The somatic reproductive tissues of C. elegans promote longevity through steroid hormone signaling
-
Yamawaki T.M., Berman J.R., Suchanek-Kavipurapu M., McCormick M., Maria Gaglia M., Lee S.J., et al. The somatic reproductive tissues of C. elegans promote longevity through steroid hormone signaling. PLoS Biology 2010, 8(8):e1000468.
-
(2010)
PLoS Biology
, vol.8
, Issue.8
-
-
Yamawaki, T.M.1
Berman, J.R.2
Suchanek-Kavipurapu, M.3
McCormick, M.4
Maria Gaglia, M.5
Lee, S.J.6
-
122
-
-
0033000965
-
A gp330/megalin-related protein is required in the major epidermis of Caenorhabditis elegans for completion of molting
-
Yochem J., Tuck S., Greenwald I., Han M. A gp330/megalin-related protein is required in the major epidermis of Caenorhabditis elegans for completion of molting. Development 1999, 126:597-606.
-
(1999)
Development
, vol.126
, pp. 597-606
-
-
Yochem, J.1
Tuck, S.2
Greenwald, I.3
Han, M.4
-
123
-
-
79960401698
-
The conserved Rieske oxygenase DAF-36/Neverland is a novel cholesterol-metabolizing enzyme
-
Yoshiyama-Yanagawa T., Enya S., Shimada-Niwa Y., Yaguchi S., Haramoto Y., Matsuya T., et al. The conserved Rieske oxygenase DAF-36/Neverland is a novel cholesterol-metabolizing enzyme. Journal of Biological Chemistry 2011, 286:25756-25762.
-
(2011)
Journal of Biological Chemistry
, vol.286
, pp. 25756-25762
-
-
Yoshiyama-Yanagawa, T.1
Enya, S.2
Shimada-Niwa, Y.3
Yaguchi, S.4
Haramoto, Y.5
Matsuya, T.6
-
124
-
-
36749043230
-
Induced pluripotent stem cell lines derived from human somatic cells
-
Yu J., Vodyanik M.A., Smuga-Otto K., Antosiewicz-Bourget J., Frane J.L., Tian S., et al. Induced pluripotent stem cell lines derived from human somatic cells. Science 2007, 318:1917-1920.
-
(2007)
Science
, vol.318
, pp. 1917-1920
-
-
Yu, J.1
Vodyanik, M.A.2
Smuga-Otto, K.3
Antosiewicz-Bourget, J.4
Frane, J.L.5
Tian, S.6
-
125
-
-
77955279152
-
Cell autonomous specification of temporal identity by Caenorhabditis elegans microRNA lin-4
-
Zhang H., Fire A.Z. Cell autonomous specification of temporal identity by Caenorhabditis elegans microRNA lin-4. Developmental Biology 2010, 344:603-610.
-
(2010)
Developmental Biology
, vol.344
, pp. 603-610
-
-
Zhang, H.1
Fire, A.Z.2
-
126
-
-
84863143896
-
Structural conservation of ligand binding reveals a bile acid-like signaling pathway in nematodes
-
Zhi X., Zhou X.E., Melcher K., Motola D.L., Gelmedin V., Hawdon J., et al. Structural conservation of ligand binding reveals a bile acid-like signaling pathway in nematodes. Journal of Biological Chemistry 2012, 287:4894-4903.
-
(2012)
Journal of Biological Chemistry
, vol.287
, pp. 4894-4903
-
-
Zhi, X.1
Zhou, X.E.2
Melcher, K.3
Motola, D.L.4
Gelmedin, V.5
Hawdon, J.6
-
127
-
-
77954144740
-
Lin28a transgenic mice manifest size and puberty phenotypes identified in human genetic association studies
-
Zhu H., Shah S., Shyh-Chang N., Shinoda G., Einhorn W.S., Viswanathan S.R., et al. Lin28a transgenic mice manifest size and puberty phenotypes identified in human genetic association studies. Nature Genetics 2010, 42:626-630.
-
(2010)
Nature Genetics
, vol.42
, pp. 626-630
-
-
Zhu, H.1
Shah, S.2
Shyh-Chang, N.3
Shinoda, G.4
Einhorn, W.S.5
Viswanathan, S.R.6
-
128
-
-
80053481600
-
The Lin28/let-7 axis regulates glucose metabolism
-
Zhu H., Shyh-Chang N., Segre A.V., Shinoda G., Shah S.P., Einhorn W.S., et al. The Lin28/let-7 axis regulates glucose metabolism. Cell 2011, 147:81-94.
-
(2011)
Cell
, vol.147
, pp. 81-94
-
-
Zhu, H.1
Shyh-Chang, N.2
Segre, A.V.3
Shinoda, G.4
Shah, S.P.5
Einhorn, W.S.6
|