nhl-2 Modulates MicroRNA Activity in Caenorhabditis elegans

Cell

Volumn 136, Issue 5, 2009, Pages 926-938

  Hammell, Christopher M ^a   Lubin, Isabella ^a   Boag, Peter R ^b   Blackwell, T Keith ^b   Ambros, Victor ^a  

^a UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

Author keywords

DEVBIO; RNA; STEMCELL

Indexed keywords

GLYCINE DEHYDROGENASE (DECARBOXYLATING); MICRORNA; NHL 2 PROTEIN; PROTEIN DERIVATIVE; RAS PROTEIN; TRIM NHL PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; BIOGENESIS; CAENORHABDITIS ELEGANS; GENE CONTROL; MUTATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION;

CAENORHABDITIS ELEGANS; METAZOA;

EID: 61349169058     PISSN: 00928674     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cell.2009.01.053     Document Type: Article

References (40)

1. Abbott A.L., Alvarez-Saavedra E., Miska E.A., Lau N.C., Bartel D.P., Horvitz H.R., and Ambros V. The let-7 MicroRNA family members mir-48, mir-84, and mir-241 function together to regulate developmental timing in Caenorhabditis elegans. Dev. Cell 9 (2005) 403-414
2. Behm-Ansmant I., Rehwinkel J., Doerks T., Stark A., Bork P., and Izaurralde E. mRNA degradation by miRNAs and GW182 requires both CCR4:NOT deadenylase and DCP1:DCP2 decapping complexes. Genes Dev. 20 (2006) 1885-1898
3. Beitel G.J., Clark S.G., and Horvitz H.R. Caenorhabditis elegans ras gene let-60 acts as a switch in the pathway of vulval induction. Nature 348 (1990) 503-509
4. Bhattacharyya S.N., Habermacher R., Martine U., Closs E.I., and Filipowicz W. Relief of microRNA-mediated translational repression in human cells subjected to stress. Cell 125 (2006) 1111-1124
5. Boag P.R., Nakamura A., and Blackwell T.K. A conserved RNA-protein complex component involved in physiological germline apoptosis regulation in C. elegans. Development 132 (2005) 4975-4986
6. Boag P.R., Atalay A., Robida S., Reinke V., and Blackwell T.K. Protection of specific maternal messenger RNAs by the P body protein CGH-1 (Dhh1/RCK) during Caenorhabditis elegans oogenesis. J. Cell Biol. 182 (2008) 543-557
7. Brenner S. The genetics of Caenorhabditis elegans. Genetics 77 (1974) 71-94
8. Chu C.Y., and Rana T.M. Translation repression in human cells by microRNA-induced gene silencing requires RCK/p54. PLoS Biol. 4 (2006) e210 10.1371/journal.pbio.0040210
9. Coller J., and Parker R. General translational repression by activators of mRNA decapping. Cell 122 (2005) 875-886
10. Coller J.M., Tucker M., Sheth U., Valencia-Sanchez M.A., and Parker R. The DEAD box helicase, Dhh1p, functions in mRNA decapping and interacts with both the decapping and deadenylase complexes. RNA 7 (2001) 1717-1727
11. Ding L., Spencer A., Morita K., and Han M. The developmental timing regulator AIN-1 interacts with miRISCs and may target the argonaute protein ALG-1 to cytoplasmic P bodies in C. elegans. Mol. Cell 19 (2005) 437-447
12. Eulalio A., Rehwinkel J., Stricker M., Huntzinger E., Yang S.F., Doerks T., Dorner S., Bork P., Boutros M., and Izaurralde E. Target-specific requirements for enhancers of decapping in miRNA-mediated gene silencing. Genes Dev. 21 (2007) 2558-2570
13. Eulalio A., Huntzinger E., and Izaurralde E. Getting to the root of miRNA-mediated gene silencing. Cell 132 (2008) 9-14
14. Eulalio A., Huntzinger E., and Izaurralde E. GW182 interaction with Argonaute is essential for miRNA-mediated translational repression and mRNA decay. Nat. Struct. Mol. Biol. 15 (2008) 346-353
15. Glasscock E., Singhania A., and Tanouye M.A. The mei-P26 gene encodes a RING finger B-box coiled-coil-NHL protein that regulates seizure susceptibility in Drosophilia. Genetics 170 (2005) 1677-1689
16. Grishok A., Pasquinelli A.E., Conte D., Li N., Parrish S., Ha I., Baillie D.L., Fire A., Ruvkun G., and Mello C.C. Genes and mechanisms related to RNA interference regulate expression of the small temporal RNAs that control C. elegans developmental timing. Cell 106 (2001) 23-34
17. Hall T.M. Multiple modes of RNA recognition by zinc finger proteins. Curr. Opin. Struct. Biol. 15 (2005) 367-373
18. Hammell C.M. The microRNA-argonaute complex: A platform for mRNA modulation. RNA Biol. 5 (2008) 8-12
19. Han M., Aroian R.V., and Sternberg P.W. The let-60 locus controls the switch between vulval and nonvulval cell fates in Caenorhabditis elegans. Genetics 126 (1990) 899-913
20. Johnson S.M., Grosshans H., Shingara J., Byrom M., Jarvis R., Cheng A., Labourier E., Reinert K.L., Brown D., and Slack F.J. RAS is regulated by the let-7 microRNA family. Cell 120 (2005) 635-647
21. Johnston R.J., and Hobert O. A microRNA controlling left/right neuronal asymmetry in Caenorhabditis elegans. Nature 426 (2003) 845-849
22. Lee R.C., and Ambros V. An extensive class of small RNAs in Caenorhabditis elegans. Science 294 (2001) 862-864
23. Li M., Jones-Rhoades M.W., Lau N.C., Bartel D.P., and Rougvie A.E. Regulatory mutations of mir-48, a C. elegans let-7 family MicroRNA, cause developmental timing defects. Dev. Cell 9 (2005) 415-422
24. Liu J., Rivas F.V., Wohlschlegel J., Yates III J.R., Parker R., and Hannon G.J. A role for the P-body component GW182 in microRNA function. Nat. Cell Biol. 7 (2005) 1261-1266
25. Mathonnet G., Fabian M.R., Svitkin Y.V., Parsyan A., Huck L., Murata T., Biffo S., Merrick W.C., Darzynkiewicz E., Pillai R.S., et al. MicroRNA inhibition of translation initiation in vitro by targeting the cap-binding complex eIF4F. Science 317 (2007) 1764-1767
26. Matthews J.M., and Sunde M. Zinc fingers-folds for many occasions. IUBMB Life 54 (2002) 351-355
27. Mello C.C., Kramer J.M., Stinchcomb D., and Ambros V. Efficient gene transfer in C.elegans: extrachromosomal maintenance and integration of transforming sequences. EMBO J. 10 (1991) 3959-3970
28. Navarro R.E., Shim E.Y., Kohara Y., Singson A., and Blackwell T.K. cgh-1, a conserved predicted RNA helicase required for gametogenesis and protection from physiological germline apoptosis in C. elegans. Development 128 (2001) 3221-3232
29. Neumuller R.A., Betschinger J., Fischer A., Bushati N., Poernbacher I., Mechtler K., Cohen S.M., and Knoblich J.A. Mei-P26 regulates microRNAs and cell growth in the Drosophila ovarian stem cell lineage. Nature 454 (2008) 241-245
30. Palmer R.E., Inoue T., Sherwood D.R., Jiang L.I., and Sternberg P.W. Caenorhabditis elegans cog-1 locus encodes GTX/Nkx6.1 homeodomain proteins and regulates multiple aspects of reproductive system development. Dev. Biol. 252 (2002) 202-213
31. Parker R., and Sheth U. P bodies and the control of mRNA translation and degradation. Mol. Cell 25 (2007) 635-646
32. Rajyaguru P., and Parker R. CGH-1 and the control of maternal mRNAs. Trends Cell Biol. 19 (2008) 24-28
33. Rehwinkel J., Behm-Ansmant I., Gatfield D., and Izaurralde E. A crucial role for GW182 and the DCP1:DCP2 decapping complex in miRNA-mediated gene silencing. RNA 11 (2005) 1640-1647
34. Sarin S., O'Meara M.M., Flowers E.B., Antonio C., Poole R.J., Didiano D., Johnston Jr. R.J., Chang S., Narula S., and Hobert O. Genetic screens for Caenorhabditis elegans mutants defective in left/right asymmetric neuronal fate specification. Genetics 176 (2007) 2109-2130
35. Slack F.J., Basson M., Liu Z., Ambros V., Horvitz H.R., and Ruvkun G. The lin-41 RBCC gene acts in the C. elegans heterochronic pathway between the let-7 regulatory RNA and the LIN-29 transcription factor. Mol. Cell 5 (2000) 659-669
36. Slack F.J., and Ruvkun G. A novel repeat domain that is often associated with RING finger and B-box motifs. Trends Biochem. Sci. 23 (1998) 474-475
37. Sulston J.E., and Horvitz H.R. Post-embryonic cell lineages of the nematode, Caenorhabditis elegans. Dev. Biol. 56 (1977) 110-156
38. Vasudevan S., Tong Y., and Steitz J.A. Switching from repression to activation: microRNAs can up-regulate translation. Science 318 (2007) 1931-1934
39. Wang B., Love T.M., Call M.E., Doench J.G., and Novina C.D. Recapitulation of short RNA-directed translational gene silencing in vitro. Mol. Cell 22 (2006) 553-560
40. Zhang L., Ding L., Cheung T.H., Dong M.Q., Chen J., Sewell A.K., Liu X., Yates III J.R., and Han M. Systematic identification of C. elegans miRISC proteins, miRNAs, and mRNA targets by their interactions with GW182 proteins AIN-1 and AIN-2. Mol. Cell 28 (2007) 598-613