The Rieske oxygenase DAF-36 functions as a cholesterol 7-desaturase in steroidogenic pathways governing longevity

Aging Cell

Volumn 10, Issue 5, 2011, Pages 879-884

  Wollam, Joshua ^a,b   Magomedova, Lilia ^c   Magner, Daniel B ^b   Shen, Yidong ^b   Rottiers, Veerle ^a   Motola, Daniel L ^d   Mangelsdorf, David J ^d   Cummins, Carolyn L ^c   Antebi, Adam ^a,b,e  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

^b MAX PLANCK INSTITUTE FOR BIOLOGY OF AGEING   (Germany)

^c UNIVERSITY OF TORONTO   (Canada)

^d UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^e UNIVERSITY OF COLOGNE   (Germany)

Author keywords

Aging; Bile acid; Development; Endocrine signaling; Hormone; Nuclear receptor

Indexed keywords

7 DEHYDROCHOLESTEROL; BILE ACID; CELL NUCLEUS RECEPTOR; CHOLESTEROL; CHOLESTEROL 7 DESATURASE; DAFACHRONIC ACID; NUCLEAR RECEPTOR DAF 12; OXYGENASE; PROTEIN DAF 36; RIESKE OXYGENASE; STEROID; UNCLASSIFIED DRUG;

ARTICLE; CAENORHABDITIS ELEGANS; DEVELOPMENTAL BIOLOGY; LONGEVITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; REPRODUCTION; STEROIDOGENESIS;

ANIMALS; CAENORHABDITIS ELEGANS; CAENORHABDITIS ELEGANS PROTEINS; CELL LINE; CHOLESTEROL; CHROMATOGRAPHY, LIQUID; DEHYDROCHOLESTEROLS; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; GENE EXPRESSION REGULATION, DEVELOPMENTAL; INSECTS; LONGEVITY; MICROSOMES; NEUROENDOCRINE CELLS; OXYGENASES; PHENOTYPE; RECEPTORS, CYTOPLASMIC AND NUCLEAR; SIGNAL TRANSDUCTION;

CAENORHABDITIS ELEGANS; MAMMALIA; METAZOA;

EID: 80052821900     PISSN: 14749718     EISSN: 14749726     Source Type: Journal    
DOI: 10.1111/j.1474-9726.2011.00733.x     Document Type: Article

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