The expression of the Alzheimer's amyloid precursor protein-like gene is regulated by developmental timing microRNAs and their targets in Caenorhabditis elegans

Developmental Biology

Volumn 315, Issue 2, 2008, Pages 418-425

  Niwa, Ryusuke ^a   Zhou, Feng ^a   Li, Chris ^b   Slack, Frank J ^a  

^a YALE UNIVERSITY   (United States)

^b CITY COLLEGE OF NEW YORK   (United States)

Author keywords

Alzheimer's disease; Amyloid precursor protein; apl 1; Caenorhabditis elegans; Developmental timing; Heterochronic genes; let 7; MicroRNA; Molting

Indexed keywords

AMYLOID BETA PROTEIN; AMYLOID PRECURSOR PROTEIN; MICRORNA; PROTEIN APL 1; UNCLASSIFIED DRUG;

ALZHEIMER DISEASE; ARTICLE; CAENORHABDITIS ELEGANS; CELL FATE; CONTROLLED STUDY; DEGENERATIVE DISEASE; DEMENTIA; DISEASE COURSE; GENE; GENE EXPRESSION REGULATION; GENE INTERACTION; GENETIC TRANSCRIPTION; HBL 1 GENE; LIN 41 GENE; LIN 42 GENE; NONHUMAN; PRIORITY JOURNAL; SENILE PLAQUE; TRANSCRIPTION REGULATION;

CAENORHABDITIS ELEGANS;

EID: 40149088267     PISSN: 00121606     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ydbio.2007.12.044     Document Type: Article

References (36)

1. A.L. Abbott E. Alvarez-Saavedra E.A. Miska N.C. Lau D.P. Bartel H.R. Horvitz V. Ambros The let-7 MicroRNA family members mir-48 , mir-84 , and mir-241 function together to regulate developmental timing in Caenorhabditis elegans Dev. Cell 9 2005 403 414
2. J.E. Abrahante E.A. Miller A.E. Rougvie Identification of heterochronic mutants in Caenorhabditis elegans . Temporal misexpression of a collagen:green fluorescent protein fusion gene Genetics 149 1998 1335 1351
3. J.E. Abrahante A.L. Daul M. Li M.L. Volk J.M. Tennessen E.A. Miller A.E. Rougvie The Caenorhabditis elegans hunchback-like gene lin-57/hbl-1 controls developmental time and is regulated by microRNAs Dev. Cell 4 2003 625 637
4. M.D. Abramoff P.J. Magelhaes S.J. Ram Image processing with image J. Biophoton. Int. 11 2004 36 42
5. V. Ambros Control of developmental timing in Caenorhabditis elegans Curr. Opin. Genet. Dev. 10 2000 428 433
6. V. Ambros H.R. Horvitz Heterochronic mutants of the nematode Caenorhabditis elegans Science 226 1984 409 416
7. D. Banerjee F. Slack Control of developmental timing by small temporal RNAs: a paradigm for RNA-mediated regulation of gene expression BioEssays 24 2002 119 129
8. M. Boehm F. Slack A developmental timing microRNA and its target regulate life span in C. elegans Science 310 2005 1954 1957
9. I. Daigle C. Li apl-1 , a Caenorhabditis elegans gene encoding a protein related to the human beta-amyloid protein precursor Proc. Natl. Acad. Sci. U. S. A. 90 1993 12045 12049
10. A.J. Enright B. John U. Gaul T. Tuschl C. Sander D.S. Marks MicroRNA targets in Drosophila Genome Biol. 5 2003 R1
11. A. Esquela-Kerscher S.M. Johnson L. Bai K. Saito J. Partridge K.L. Reinert F.J. Slack Post-embryonic expression of C. elegans microRNAs belonging to the lin-4 and let-7 families in the hypodermis and the reproductive system Dev. Dyn. 234 2005 868 877
12. A.R. Frand S. Russel G. Ruvkun Functional genomic analysis of C. elegans molting PLoS Biol. 3 2005 e312
13. A.G. Fraser R.S. Kamath P. Zipperlen M. Martinez-Campos M. Sohrmann J. Ahringer Functional genomic analysis of C. elegans chromosome I by systematic RNA interference Nature 408 2000 325 330
14. M. Goedert M.G. Spillantini A century of Alzheimer's disease Science 314 2006 777 781
15. M. Gralle S.T. Ferreira Structure and functions of the human amyloid precursor protein: the whole is more than the sum of its parts Prog. Neurobiol. 82 2007 11 32
16. M.O. Grimm H.S. Grimm T. Hartmann Amyloid beta as a regulator of lipid homeostasis Trends Mol. Med. 13 2007 337 344
17. H. Grosshans T. Johnson K.L. Reinert M. Gerstein F.J. Slack The temporal patterning microRNA let-7 regulates several transcription factors at the larval to adult transition in C. elegans Dev. Cell 8 2005 321 330
18. J. Hardy D.J. Selkoe The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics Science 297 2002 353 356
19. G.D. Hayes A.R. Frand G. Ruvkun The mir-84 and let-7 paralogous microRNA genes of Caenorhabditis elegans direct the cessation of molting via the conserved nuclear hormone receptors NHR-23 and NHR-25 Development 133 2006 4631 4641
20. A. Hornsten J. Lieberthal S. Fadia R. Malins L. Ha X. Xu I. Daigle M. Markowitz G. O'Connor R. Plasterk C. Li APL-1, a Caenorhabditis elegans protein related to the human beta-amyloid precursor protein, is essential for viability Proc. Natl. Acad. Sci. U. S. A. 104 2007 1971 1976
21. B. John A.J. Enright A. Aravin T. Tuschl C. Sander D.S. Marks Human microRNA targets PLoS Biol. 2 2004 e363
22. I.L. Johnstone Y. Shafi J.D. Barry Molecular analysis of mutations in the Caenorhabditis elegans collagen gene dpy-7 EMBO J. 11 1992 3857 3863
23. R.S. Kamath A.G. Fraser Y. Dong G. Poulin R. Durbin M. Gotta A. Kanapin N. Le Bot S. Moreno M. Sohrmann D.P. Welchman P. Zipperlen J. Ahringer Systematic functional analysis of the Caenorhabditis elegans genome using RNAi Nature 421 2003 231 237
24. S. Lall D. Grun A. Krek K. Chen Y.L. Wang C.N. Dewey P. Sood T. Colombo N. Bray P. Macmenamin H.L. Kao K.C. Gunsalus L. Pachter F. Piano N. Rajewsky A genome-wide map of conserved microRNA targets in C. elegans Curr. Biol. 16 2006 460 471
25. D. Levitan I. Greenwald Facilitation of lin-12 -mediated signalling by sel-12 , a Caenorhabditis elegans S182 Alzheimer's disease gene Nature 377 1995 351 354
26. L.P. Lim N.C. Lau E.G. Weinstein A. Abdelhakim S. Yekta M.W. Rhoades C.B. Burge D.P. Bartel The microRNAs of Caenorhabditis elegans Genes Dev. 17 2003 991 1008
27. S.Y. Lin S.M. Johnson M. Abraham M.C. Vella A. Pasquinelli C. Gamberi E. Gottlieb F.J. Slack The C. elegans hunchback homolog, hbl-1 , controls temporal patterning and is a probable microRNA target Dev. Cell 4 2003 639 650
28. C. McKeown V. Praitis J. Austin sma-1 encodes a betaH-spectrin homolog required for Caenorhabditis elegans morphogenesis Development 125 1998 2087 2098
29. B.J. Reinhart F.J. Slack M. Basson A.E. Pasquinelli J.C. Bettinger A.E. Rougvie H.R. Horvitz G. Ruvkun The 21-nucleotide let-7 RNA regulates developmental timing in Caenorhabditis elegans Nature 403 2000 901 906
30. A.E. Rougvie Intrinsic and extrinsic regulators of developmental timing: from miRNAs to nutritional cues Development 132 2005 3787 3798
31. A.E. Rougvie V. Ambros The heterochronic gene lin-29 encodes a zinc finger protein that controls a terminal differentiation event in Caenorhabditis elegans Development 121 1995 2491 2500
32. A. Rovelet-Lecrux D. Hannequin G. Raux N. Le Meur A. Laquerriere A. Vital C. Dumanchin S. Feuillette A. Brice M. Vercelletto F. Dubas T. Frebourg D. Campion APP locus duplication causes autosomal dominant early-onset Alzheimer disease with cerebral amyloid angiopathy Nat. Genet. 38 2006 24 26
33. A. Schmitz R. Tikkanen G. Kirfel V. Herzog The biological role of the Alzheimer amyloid precursor protein in epithelial cells Histochem. Cell Biol. 117 2002 171 180
34. F.J. Slack M. Basson Z. Liu V. Ambros H.R. Horvitz G. Ruvkun The lin-41 RBCC gene acts in the C. elegans heterochronic pathway between the let-7 regulatory RNA and the LIN-29 transcription factor Mol. Cell 5 2000 659 669
35. L. Timmons A. Fire Specific interference by ingested dsRNA Nature 395 1998 854
36. N. Zambrano M. Bimonte S. Arbucci D. Gianni T. Russo P. Bazzicalupo feh-1 and apl-1 , the Caenorhabditis elegans orthologues of mammalian Fe65 and beta-amyloid precursor protein genes, are involved in the same pathway that controls nematode pharyngeal pumping J. Cell. Sci. 115 2002 1411 1422