APL-1, a Caenorhabditis elegans protein related to the human β-amyloid precursor protein, is essential for viability

Proceedings of the National Academy of Sciences of the United States of America

Volumn 104, Issue 6, 2007, Pages 1971-1976

  Hornsten, Angela ^a   Lieberthal, Jason ^a,e   Fadia, Shruti ^a,f   Malins, Richard ^b,g   Ha, Lawrence ^c   Xu, Xiaomeng ^c   Daigle, Isabelle ^b   Markowitz, Mindy ^a,h   O'Connor, Gregory ^a,i   Plasterk, Ronald ^d   Li, Chris ^b,c  

^a BOSTON UNIVERSITY   (United States)

^b Boston University   (United States)

^c CITY COLLEGE OF NEW YORK   (United States)

^d HUBRECHT INSTITUTE   (Netherlands)

^e NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

^f RUTGERS ROBERT WOOD JOHNSON MEDICAL SCHOOL   (United States)

^g UNIVERSITY OF OXFORD   (United Kingdom)

^h LENOX HILL HOSPITAL   (United States)

ⁱ NOVARTIS INSTITUTES FOR BIOMEDICAL RESEARCH   (United States)

Author keywords

Alzheimer's disease; Genetics; Model system

Indexed keywords

AMYLOID BETA PROTEIN; AMYLOID PRECURSOR PROTEIN; CAENORHABDITIS ELEGANS PROTEIN; GAMMA SECRETASE;

ALZHEIMER DISEASE; ANIMAL CELL; ANIMAL EXPERIMENT; APL 1 GENE; ARTICLE; CAENORHABDITIS ELEGANS; CELL TYPE; CELL VIABILITY; DEGENERATIVE DISEASE; DNA SEQUENCE; ENZYME ACTIVITY; GENE; GENE MUTATION; GENE OVEREXPRESSION; GENOTYPE; LARVAL DEVELOPMENT; NEUROLOGIC DISEASE; NONHUMAN; PLASMID; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL;

AMYLOID BETA-PROTEIN PRECURSOR; ANIMALS; CAENORHABDITIS ELEGANS; CAENORHABDITIS ELEGANS PROTEINS; HUMANS; LARVA; MEMBRANE PROTEINS; MOLTING;

CAENORHABDITIS ELEGANS;

EID: 33846923049     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0603997104     Document Type: Article

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