Nuclear erythroid 2-related factor 2: A novel potential therapeutic target for liver fibrosis

Food and Chemical Toxicology

Volumn 59, Issue , 2013, Pages 421-427

  Yang, Jing Jing ^a   Tao, Hui ^a   Huang, Cheng ^a   Li, Jun ^a  

^a ANHUI MEDICAL UNIVERSITY   (China)

Author keywords

Hepatic stellate cell; Liver fibrosis; Nuclear erythroid 2 related factor 2; Oxidative stress

Indexed keywords

BUTYLATED HYDROXYANISOLE; GLYCYRRHETINIC ACID; OLEANOLIC ACID; OLTIPRAZ; SULFORAPHANE; TRANSCRIPTION FACTOR NRF2; TRITERPENOID;

CELL ACTIVATION; CELL DIFFERENTIATION; DRUG MECHANISM; DRUG TARGETING; GENE EXPRESSION; HUMAN; INTRAHEPATIC CHOLESTASIS; LIVER FIBROSIS; LIVER INJURY; LIVER PROTECTION; NONHUMAN; OXIDATIVE STRESS; PROTEIN FUNCTION; REVIEW; SIGNAL TRANSDUCTION; STELLATE CELL;

Α-SMA; Α-SMOOTH MUSCLE ACTIN; ACETAMINOPHEN; ANTIOXIDANT RESPONSE ELEMENT; APAP; ARE; ECM; EGF; EPIDERMAL GROWTH FACTOR; ERK; EXTRACELLULAR MATRIX; EXTRACELLULAR SIGNAL-REGULATED KINASE; HCC; HEME OXYGENASE-1; HEPATIC STELLATE CELL; HEPATIC STELLATE CELLS; HEPATOCELLULAR CARCINOMA; HO-1; HSC; ISOTHIOCYANATES; ITC; KEAP1; KELCH-LIKE ECH-ASSOCIATED PROTEIN 1; LIVER FIBROSIS; MAMMALIAN TARGET OF RAPAMYCIN; MAPK; MITOGEN-ACTIVATED PROTEIN KINASE; MTOR; NASH; NF-ΚB; NONALCOHOLIC STEATOHEPATITIS; NOTCH 1; NOTCH HOMOLOG 1; NRF2; NUCLEAR ERYTHROID 2-RELATED FACTOR 2; NUCLEAR FACTOR-ΚB; OXIDATIVE STRESS; PCP; PDGF; PENTACHLOROPHENOL; PERK; PHOSPHOINOSITIDE 3-KINASE INHIBITOR; PI3K; PKC; PKR-LIKE ENDOPLASMIC RETICULUM KINASE; PLATELET-DERIVED GROWTH FACTOR; PROTEIN KINASE C; REACTIVE NITROGEN SPECIES; REACTIVE OXYGEN SPECIES; RNS; ROS; TBARS; TGF-Β1; THIOBARBITURIC- ACID-REACTIVE SUBSTANCES; TRANSFORMING GROWTH FACTOR-Β1;

ANIMALS; ANTIOXIDANTS; GENE EXPRESSION REGULATION; HEPATIC STELLATE CELLS; HUMANS; LIVER CIRRHOSIS; MODELS, BIOLOGICAL; MOLECULAR TARGETED THERAPY; NF-E2-RELATED FACTOR 2; OXIDATIVE STRESS; SIGNAL TRANSDUCTION;

EID: 84880422286     PISSN: 02786915     EISSN: 18736351     Source Type: Journal    
DOI: 10.1016/j.fct.2013.06.018     Document Type: Review

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