A crucial role of Nrf2 in in vivo defense against oxidative damage by an environmental pollutant, pentachlorophenol

Toxicological Sciences

Volumn 90, Issue 1, 2006, Pages 111-119

  Umemura, Takashi ^a   Kuroiwa, Yuichi ^a   Kitamura, Yasuki ^a   Ishii, Yuji ^a,b   Kanki, Keita ^a   Kodama, Yukio ^a   Itoh, Ken ^c   Yamamoto, Masayuki ^c   Nishikawa, Akiyoshi ^a   Hirose, Masao ^a  

^a NATIONAL INSTITUTE OF HEALTH SCIENCES   (Japan)

^b HOSHI UNIVERSITY   (Japan)

^c UNIVERSITY OF TSUKUBA   (Japan)

Author keywords

8 hydroxydeoxyguanosine; Cell proliferation; NQO1; Nrf2; Pentachlorophenol

Indexed keywords

8 HYDROXYDEOXYGUANOSINE; ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; BROXURIDINE; CYTOCHROME P450 1A2; DNA; ETHOXYRESORUFIN DEETHYLASE; GLUCURONOSYLTRANSFERASE; MICROSOMAL AMINOPEPTIDASE; PENTACHLOROPHENOL; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE (PHOSPHATE) DEHYDROGENASE (QUINONE); THIOBARBITURIC ACID REACTIVE SUBSTANCE; TRANSCRIPTION FACTOR NRF2;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL FOOD; ANIMAL MODEL; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; CELL LABELING; CELL PROLIFERATION; CELL PROTECTION; CELLULAR IMMUNITY; CHEMICAL CARCINOGENESIS; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME ANALYSIS; HISTOPATHOLOGY; IN VIVO STUDY; LIVER CARCINOGENESIS; LIVER TOXICITY; LIVER WEIGHT; MALE; MOUSE; NECROSIS; NONHUMAN; OXIDATIVE STRESS; PROTEIN FUNCTION;

ALKALINE PHOSPHATASE; ANIMALS; CELL PROLIFERATION; CYTOCHROME P-450 CYP1A2; DEOXYGUANOSINE; DIET; DNA DAMAGE; DOSE-RESPONSE RELATIONSHIP, DRUG; ENVIRONMENTAL POLLUTANTS; GLUCURONOSYLTRANSFERASE; HEPATOCYTES; LIVER; MICE; MICE, INBRED ICR; MICE, KNOCKOUT; NADPH DEHYDROGENASE; NECROSIS; NF-E2-RELATED FACTOR 2; ORGAN SIZE; OXIDATIVE STRESS; PENTACHLOROPHENOL;

ANIMALIA;

EID: 33144488472     PISSN: 10966080     EISSN: None     Source Type: Journal    
DOI: 10.1093/toxsci/kfj076     Document Type: Article

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