Indoxyl sulfate, a uremic toxin, downregulates renal expression of Nrf2 through activation of NF-κB

BMC Nephrology

Volumn 14, Issue 1, 2013, Pages

  Bolati, Dilinaer ^a   Shimizu, Hidehisa ^a   Yisireyili, Maimaiti ^a   Nishijima, Fuyuhiko ^b   Niwa, Toshimitsu ^a  

^a NAGOYA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b KUREHA CORPORATION   (Japan)

Author keywords

8 hydroxydeoxyguanosine (8 OHdG); Heme oxygenase 1 (HO 1); NAD(P)H:quinone oxidoreductase 1 (NQO1); NF B; Proximal tubular cells

Indexed keywords

8 HYDROXYDEOXYGUANOSINE; AST 120; HEME OXYGENASE 1; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDICAN; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE (PHOSPHATE) DEHYDROGENASE (QUINONE); SMALL INTERFERING RNA; TRANSCRIPTION FACTOR NRF2; TRANSCRIPTION FACTOR RELA;

ANIMAL TISSUE; ARTICLE; CHRONIC KIDNEY DISEASE; COMPARATIVE STUDY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DOWN REGULATION; GENE TARGETING; HUMAN; HUMAN CELL; HYPERTENSION; KIDNEY; KIDNEY PROXIMAL TUBULE; MALE; NONHUMAN; PROTEIN ANALYSIS; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; RAT; UPREGULATION;

ANIMALS; CELL LINE; DOWN-REGULATION; HUMANS; INDICAN; KIDNEY; MALE; NF-E2-RELATED FACTOR 2; NF-KAPPA B; RATS; RATS, SPRAGUE-DAWLEY; SIGNAL TRANSDUCTION; UREMIA;

EID: 84874404062     PISSN: None     EISSN: 14712369     Source Type: Journal    
DOI: 10.1186/1471-2369-14-56     Document Type: Article

References (29)

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