Modulation of Nrf2/Keap1 system by Wasabi 6-methylthiohexyl isothiocyanate in ARE-mediated NQO1 expression

Molecular Nutrition and Food Research

Volumn 57, Issue 5, 2013, Pages 854-864

  Korenori, Yoshimi ^a   Tanigawa, Shunsuke ^a   Kumamoto, Takuma ^a   Qin, Si ^a   Daikoku, Yosuke ^a   Miyamori, Koji ^a   Nagai, Masashi ^b   Hou, De Xing ^a  

^a KAGOSHIMA UNIVERSITY   (Japan)

^b Kinjirushi Co Ltd   (Japan)

Author keywords

6 MTITC; ARE activation; Keap1 modification; NQO1; Nrf2 ubiquitination

Indexed keywords

6 METHYLTHIOHEXYL ISOTHIOCYANATE; 6-METHYLTHIOHEXYL ISOTHIOCYANATE; ANTIOXIDANT; ISOTHIOCYANIC ACID DERIVATIVE; KEAP1 PROTEIN, HUMAN; NFE2L2 PROTEIN, HUMAN; NQO1 PROTEIN, HUMAN; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE (PHOSPHATE) DEHYDROGENASE (QUINONE); SIGNAL PEPTIDE; TRANSCRIPTION FACTOR NRF2;

ARTICLE; CELL PROTECTION; CELL STRAIN HEPG2; CHEMISTRY; DNA RESPONSIVE ELEMENT; DRUG EFFECT; EUTREMA; GEL MOBILITY SHIFT ASSAY; GENE EXPRESSION REGULATION; GENETICS; HUMAN; METABOLISM; REPORTER GENE; SIGNAL TRANSDUCTION;

ANTIOXIDANTS; CYTOPROTECTION; ELECTROPHORETIC MOBILITY SHIFT ASSAY; GENE EXPRESSION REGULATION; GENES, REPORTER; HEP G2 CELLS; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; ISOTHIOCYANATES; NAD(P)H DEHYDROGENASE (QUINONE); NF-E2-RELATED FACTOR 2; RESPONSE ELEMENTS; SIGNAL TRANSDUCTION; WASABIA;

EUTREMA WASABI;

EID: 84876427732     PISSN: 16134125     EISSN: 16134133     Source Type: Journal    
DOI: 10.1002/mnfr.201200689     Document Type: Article

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