Icariside II enhances Nrf2 nuclear translocation to upregulate phase II detoxifying enzyme expression coupled with the ERK, Akt and JNK signaling pathways

Molecules

Volumn 16, Issue 11, 2011, Pages 9234-9244

  Gu, Jing ^a   Sun, Xuechao ^a   Wang, Guonian ^a   Li, Mingming ^a   Meng, Chi ^a  

^a HARBIN MEDICAL UNIVERSITY   (China)

Author keywords

Akt; ERK; HepG2 cells; Icariside II; JNK; Nrf2

Indexed keywords

ANTIOXIDANT; ENZYME INHIBITOR; FLAVONOID; GLUTATHIONE; ICARISID II; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN KINASE B; STRESS ACTIVATED PROTEIN KINASE; TRANSCRIPTION FACTOR NRF2;

ACTIVE TRANSPORT; ANIMAL; ARTICLE; CELL PROLIFERATION; CELL STRAIN HEPG2; CHEMICAL STRUCTURE; CHEMISTRY; DRUG DETOXIFICATION; DRUG EFFECT; HUMAN; METABOLISM; PHYSIOLOGY; SIGNAL TRANSDUCTION;

ACTIVE TRANSPORT, CELL NUCLEUS; ANIMALS; ANTIOXIDANTS; CELL PROLIFERATION; ENZYME INHIBITORS; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FLAVONOIDS; GLUTATHIONE; HEP G2 CELLS; HUMANS; JNK MITOGEN-ACTIVATED PROTEIN KINASES; METABOLIC DETOXICATION, PHASE II; MOLECULAR STRUCTURE; NF-E2-RELATED FACTOR 2; PROTO-ONCOGENE PROTEINS C-AKT; SIGNAL TRANSDUCTION;

EID: 82255181679     PISSN: None     EISSN: 14203049     Source Type: Journal    
DOI: 10.3390/molecules16119234     Document Type: Article

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