Inhibitor of Nrf2 (INrf2 or Keap1) protein degrades Bcl-xL via phosphoglycerate mutase 5 and controls cellular apoptosis

Journal of Biological Chemistry

Volumn 286, Issue 52, 2011, Pages 44542-44556

  Niture, Suryakant K ^a   Jaiswal, Anil K ^a  

^a UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADAPTOR PROTEINS; ANTI-APOPTOTIC FACTOR; CASPASE-3; CO-IMMUNOPRECIPITATION ASSAYS; CYTOCHROME C; CYTOSOLS; DNA FRAGMENTATION; HETERODIMERIZATION; MASTER REGULATORS; OVER-EXPRESSION; UBIQUITINATION;

CELL DEATH; DEGRADATION; GENE EXPRESSION; GENE EXPRESSION REGULATION; MASS SPECTROMETRY; MITOCHONDRIA;

PROTEINS;

CASPASE 3; CASPASE 7; CYTOCHROME C; ETOPOSIDE; KELCH LIKE ECH ASSOCIATED PROTEIN 1; PHOSPHOGLYCERATE MUTASE; PHOSPHOGLYCERATE MUTASE FAMILY 5; PROTEIN BAX; PROTEIN BCL XL; PROTEIN VARIANT; SMALL INTERFERING RNA; TERT BUTYLHYDROQUINONE; UNCLASSIFIED DRUG;

ANIMAL CELL; APOPTOSIS; ARTICLE; CONTROLLED STUDY; CYTOSOL; DIMERIZATION; DNA FRAGMENTATION; ENZYME ACTIVATION; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; MASS SPECTROMETRY; MITOCHONDRION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; PROTEIN SECRETION; PROTEIN STABILITY; REGULATORY MECHANISM; UBIQUITINATION;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; AMINO ACID SUBSTITUTION; ANIMALS; APOPTOSIS; BCL-X PROTEIN; CARRIER PROTEINS; CASPASE 3; CASPASE 7; CELL LINE, TUMOR; CULLIN PROTEINS; CYTOCHROMES C; CYTOSKELETAL PROTEINS; CYTOSOL; DNA FRAGMENTATION; MICE; MITOCHONDRIA; MULTIPROTEIN COMPLEXES; MUTATION, MISSENSE; PHOSPHOGLYCERATE MUTASE; PROTEIN STABILITY; PROTEIN STRUCTURE, TERTIARY; PROTEOLYSIS; UBIQUITINATION;

EID: 84455192645     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.275073     Document Type: Article

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