Achyranthes japonica exhibits anti-inflammatory effect via NF-κB suppression and HO-1 induction in macrophages

Journal of Ethnopharmacology

Volumn 144, Issue 1, 2012, Pages 109-117

  Young Bang, Soo ^a   Kim, Ji Hee ^a   Kim, Hee Young ^a   Ji Lee, Young ^a   Young Park, Sun ^a   Joon Lee, Sang ^a   Kim, Younghee ^a  

^a Pusan National University   (South Korea)

Author keywords

Achyranthes japonica; Heme oxygenase 1 (HO 1); Inducible nitric oxide synthase (iNOS); NF E2 related factor 2 (Nrf2); Nitric oxide (NO); Nuclear factor kappaB (NF B)

Indexed keywords

ACHYRANTHES JAPONICA ROOT EXTRACT; HEME OXYGENASE 1; I KAPPA B ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; LIPOPOLYSACCHARIDE; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; PLANT EXTRACT; SMALL INTERFERING RNA; STRESS ACTIVATED PROTEIN KINASE; SYNAPTOPHYSIN; TRANSCRIPTION FACTOR NRF2; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CELL VIABILITY; CONTROLLED STUDY; DRUG MECHANISM; ENZYME ACTIVITY; GEL MOBILITY SHIFT ASSAY; IMMUNOCYTOCHEMISTRY; IMMUNOSUPPRESSIVE TREATMENT; MOUSE; NONHUMAN; PERITONEUM MACROPHAGE; PROTEIN ANALYSIS; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION;

ACHYRANTHES; ANIMALS; ANTI-INFLAMMATORY AGENTS; CELL LINE; HEME OXYGENASE-1; I-KAPPA B PROTEINS; LIPOPOLYSACCHARIDES; MACROPHAGES; MAP KINASE SIGNALING SYSTEM; MEDICINE, KOREAN TRADITIONAL; MEMBRANE PROTEINS; MICE; MICE, INBRED C57BL; NF-E2-RELATED FACTOR 2; NF-KAPPA B; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE II; PLANT EXTRACTS; PLANT ROOTS;

ACHYRANTHES JAPONICA;

EID: 84867517012     PISSN: 03788741     EISSN: 18727573     Source Type: Journal    
DOI: 10.1016/j.jep.2012.08.037     Document Type: Article

References (38)

1. D.K. Ahn Illustrated Book of Korean Medicinal Herbs 2003 Kyohak Publishing Co pp. 628
2. M. Bonelli, A. Savitskaya, C.W. Steiner, E. Rath, M. Bilban, O. Wagner, F.H. Bach, J.S. Smolen, and C. Scheinecker Heme oxygenase-1 end-products carbon monoxide and biliverdin ameliorate murine collagen induced arthritis Clinical and Experimental Rheumatology 30 2012 73 78
3. J. Brown, H. Wang, G.N. Hajishengallis, and M. Martin TLR-signaling networks: an integration of adaptor molecules, kinases, and cross-talk Journal of Dental Research 90 2011 417 427
4. C. Chen, Y.H. Chen, and W.W. Lin Involvement of p38 mitogen-activated protein kinase in lipopolysaccharide-induced iNOS and COX-2 expression in J774 macrophages Immunology 97 1999 124 129
5. S. Cuzzocrea, P.K. Chatterjee, E. Mazzon, M.C. McDonald, L. Dugo, R. Di Paola, I. Serraino, D. Britti, A.P. Caputi, and C. Thiemermann Beneficial effects of GW274150, a novel, potent and selective inhibitor of iNOS activity, in a rodent model of collagen-induced arthritis European Journal of Pharmacology 453 2002 119 129
6. M.R. Edwards, N.W. Bartlett, D. Clarke, M. Birrell, M. Belvisi, and S.L. Johnston Targeting the NF-kappaB pathway in asthma and chronic obstructive pulmonary disease Pharmacology & Therapeutics 121 2009 1 13
7. P. Fagone, K. Mangano, M. Coco, V. Perciavalle, G. Garotta, C.C. Romao, and F. Nicoletti Therapeutic potential of carbon monoxide in multiple sclerosis Clinical and Experimental Immunology 167 2012 179 187
8. M. Guha, and N. Mackman LPS induction of gene expression in human monocytes Cellular Signalling 13 2001 85 94
9. B.H. Han, H.J. Chi, Y.N. Han, and K.S. Ryu Screening on the anti-inflammatory activity of crude drugs Korean Journal of Pharmacognosy 3 1972 205 208
10. K. Itoh, J. Mimura, and M. Yamamoto Discovery of the negative regulator of Nrf2, Keap1: a historical overview Antioxidants & Redox Signaling 13 2010 1665 1678
11. K. Jarvinen, K. Vuolteenaho, R. Nieminen, T. Moilanen, R.G. Knowles, and E. Moilanen Selective iNOS inhibitor 1400W enhances anti-catabolic IL-10 and reduces destructive MMP-10 in OA cartilage. Survey of the effects of 1400W on inflammatory mediators produced by OA cartilage as detected by protein antibody array Clinical and Experimental Rheumatology 26 2008 275 282
12. S. Jung, J.H. Lee, Y.C. Lee, and H.I. Moon Inhibitory effects of three oleanolic acid glycosides from Achyranthes japonica on the complement classical pathway Immunopharmacology and Immunotoxicology 34 2012 213 215
13. J. Kim, J. Kim, and D. Kang A study on discriminative criteria of 6 kinds of Achyranthis radix using HPLC/DAD: isolation and identification of 20-hydroxyecdysone from Achyranthes japonica NAKAI and comparison of patterns of Achyranthis radix from different locations by HPLC. Korean Journal of Herbology 23 2008 109 116
14. S.H. Kim, J. Kim, and R.P. Sharma Inhibition of p38 and ERK MAP kinases blocks endotoxin-induced nitric oxide production and differentially modulates cytokine expression Pharmacological Research 49 2004 433 439
15. Y. Kim, J.S. Moon, K.S. Lee, S.Y. Park, J. Cheong, H.S. Kang, H.Y. Lee, and H.D. Kim Ca2/calmodulin-dependent protein phosphatase calcineurin mediates the expression of iNOS through IKK and NF-kappaB activity in LPS-stimulated mouse peritoneal macrophages and RAW 264.7 cells Biochemical and Biophysical Research Communications 314 2004 695 703
16. J.C. Kim, G.J. Choi, S.W. Lee, J.S. Kim, K.Y. Chung, and K.Y. Cho Screening extracts of Achyranthes japonica and Rumex crispus for activity against various plant pathogenic fungi and control of powdery mildew Pest Management Science 60 2004 803 808
17. Y.J. Kim, S.Y. Hwang, E.S. Oh, S. Oh, and I.O. Han IL-1beta, an immediate early protein secreted by activated microglia, induces iNOS/NO in C6 astrocytoma cells through p38 MAPK and NF-kappaB pathways Journal of Neuroscience Research 84 2006 1037 1046
18. G. Kronke, V.N. Bochkov, J. Huber, F. Gruber, S. Bluml, A. Furnkranz, A. Kadl, B.R. Binder, and N. Leitinger Oxidized phospholipids induce expression of human heme oxygenase-1 involving activation of cAMP-responsive element-binding protein The Journal of Biological Chemistry 278 2003 51006 51014
19. C.J. Lowenstein, E.W. Alley, P. Raval, A.M. Snowman, S.H. Snyder, S.W. Russell, and W.J. Murphy Macrophage nitric oxide synthase gene: two upstream regions mediate induction by interferon gamma and lipopolysaccharide Proceedings of the National Academy of Sciences of the United States of America 90 1993 9730 9734
20. J. MacMicking, Q.W. Xie, and C. Nathan Nitric oxide and macrophage function Annual Review of Immunology 15 1997 323 350
21. F. Mercurio, and A.M. Manning Multiple signals converging on NF-kappaB Current Opinion in Cell Biology 11 1999 226 232
22. S. Moncada, R.M. Palmer, and E.A. Higgs Nitric oxide: physiology, pathophysiology, and pharmacology Pharmacological Reviews 43 1991 109 142
23. H. Motohashi, F. Katsuoka, J.D. Engel, and M. Yamamoto Small Maf proteins serve as transcriptional cofactors for keratinocyte differentiation in the Keap1-Nrf2 regulatory pathway Proceedings of the National Academy of Sciences of the United States of America 101 2004 6379 6384
24. L.E. Otterbein, F.H. Bach, J. Alam, M. Soares, Lu, H. Tao, M. Wysk, R.J. Davis, R.A. Flavell, and A.M. Choi Carbon monoxide has anti-inflammatory effects involving the mitogen-activated protein kinase pathway Nature Medicine 6 2000 422 428
25. M. Overhaus, B.A. Moore, J.E. Barbato, F.F. Behrendt, J.G. Doering, and A.J. Bauer Biliverdin protects against polymicrobial sepsis by modulating inflammatory mediators American Journal of Physiology - Gastrointestinal and Liver Physiology 290 2006 G695 G703
26. S.Y. Park, G.Y. Park, W.S. Ko, and Y. Kim Dichroa febrifuga Lour. inhibits the production of IL-1beta and IL-6 through blocking NF-kappaB, MAPK and Akt activation in macrophages Journal of Ethnopharmacology 125 2009 246 251
27. J.P. Pelletier, D. Jovanovic, J.C. Fernandes, P. Manning, J.R. Connor, M.G. Currie, J.A. Di Battista, and J. Martel-Pelletier Reduced progression of experimental osteoarthritis in vivo by selective inhibition of inducible nitric oxide synthase Arthritis and Rheumatism 41 1998 1275 1286
28. J.A. Roman-Blas, and S.A. Jimenez Targeting NF-kappaB: a promising molecular therapy in inflammatory arthritis International Reviews of Immunology 27 2008 351 374
29. S.W. Ryter, J. Alam, and A.M. Choi Heme oxygenase-1/carbon monoxide: from basic science to therapeutic applications Physiological Reviews 86 2006 583 650
30. J.K. Sarady-Andrews, F. Liu, D. Gallo, A. Nakao, M. Overhaus, R. Ollinger, A.M. Choi, and L.E. Otterbein Biliverdin administration protects against endotoxin-induced acute lung injury in rats American Journal of Physiology.Lung Cellular and Molecular Physiology 289 2005 L1131 L1137
31. G.J. Southan, and C. Szabo Selective pharmacological inhibition of distinct nitric oxide synthase isoforms Biochemical Pharmacology 51 1996 383 394
32. K. Srisook, C. Kim, and Y.N. Cha Molecular mechanisms involved in enhancing HO-1 expression: de-repression by heme and activation by Nrf2, the one-two punch Antioxidants & Redox Signaling 7 2005 1674 1687
33. G.Y. Suh, Y. Jin, A.K. Yi, X.M. Wang, and A.M. Choi CCAAT/enhancer- binding protein mediates carbon monoxide-induced suppression of cyclooxygenase-2 American Journal of Respiratory Cell and Molecular Biology 35 2006 220 226
34. T. Takagi, Y. Naito, K. Uchiyama, and T. Yoshikawa The role of heme oxygenase and carbon monoxide in inflammatory bowel disease Redox Report: Communications in Free Radical Research 15 2010 193 201
35. M.L. Wu, Y.C. Ho, C.Y. Lin, and S.F. Yet Heme oxygenase-1 in inflammation and cardiovascular disease American Journal of Cardiovascular Disease 1 2011 150 158
36. Q.W. Xie, Y. Kashiwabara, and C. Nathan Role of transcription factor NF-kappa B/Rel in induction of nitric oxide synthase Journal of Biological Chemistry 269 1994 4705 4708
37. J. Yan, and J.M. Greer NF-kappa B, a potential therapeutic target for the treatment of multiple sclerosis CNS & Neurological Disorders Drug Targets 7 2008 536 557
38. H.S. Yun-Choi, S.O. Kim, J.H. Kim, J.R. Lee, and H.I. Cho Modified smear method for screening potential inhibitors of platelet aggregation from plant sources Journal of Natural Products 48 1985 363 370