Higenamine reduces HMGB1 during hypoxia-induced brain injury by induction of heme oxygenase-1 through PI3K/Akt/Nrf-2 signal pathways

Apoptosis

Volumn 17, Issue 5, 2012, Pages 463-474

  Ha, Yu Mi ^a   Kim, Min Young ^a   Park, Min Kyu ^a   Lee, Young Soo ^a   Kim, Young Min ^a   Kim, Hye Jung ^a   Lee, Jae Heun ^a   Chang, Ki Churl ^a  

^a Gyeongsang National University   (South Korea)

Author keywords

Heme oxygenase 1; HMGB1; Ischemic damage; PI3 kinase; Stroke

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; CASPASE; GLUCOSE OXIDASE; HEME OXYGENASE 1; HIGENAMINE; HIGH MOBILITY GROUP B1 PROTEIN; LUCIFERASE; MYELOPEROXIDASE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN BAX; PROTEIN BCL 2; PROTEIN KINASE B; PROTOPORPHYRIN ZINC; RECOMBINANT PROTEIN; SIGNAL PEPTIDE; TRANSCRIPTION FACTOR NRF2;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BRAIN CELL; BRAIN INFARCTION SIZE; CELL NUCLEUS; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INDUCTION; HYPOTHESIS; HYPOXIC ISCHEMIC ENCEPHALOPATHY; IN VITRO STUDY; IN VIVO STUDY; MALE; MIDDLE CEREBRAL ARTERY OCCLUSION; MORTALITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RAT;

ALKALOIDS; ANIMALS; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; CELL HYPOXIA; CELL SURVIVAL; CELLS, CULTURED; CHROMONES; ENZYME INDUCTION; HEME OXYGENASE (DECYCLIZING); HMGB1 PROTEIN; HYPOXIA-ISCHEMIA, BRAIN; INFARCTION, MIDDLE CEREBRAL ARTERY; MALE; MORPHOLINES; NEUROPROTECTIVE AGENTS; NF-E2-RELATED FACTOR 2; OXIDATIVE STRESS; PEROXIDASE; PHOSPHATIDYLINOSITOL 3-KINASES; PROTO-ONCOGENE PROTEINS C-AKT; RATS; RATS, SPRAGUE-DAWLEY; RECOMBINANT PROTEINS; SIGNAL TRANSDUCTION; TETRAHYDROISOQUINOLINES;

RATTUS;

EID: 84862489059     PISSN: 13608185     EISSN: 1573675X     Source Type: Journal    
DOI: 10.1007/s10495-011-0688-8     Document Type: Article

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